DE69523044D1 - Block- und pfropfcopolymere und dazu gehöriges verfahren - Google Patents
Block- und pfropfcopolymere und dazu gehöriges verfahrenInfo
- Publication number
- DE69523044D1 DE69523044D1 DE69523044T DE69523044T DE69523044D1 DE 69523044 D1 DE69523044 D1 DE 69523044D1 DE 69523044 T DE69523044 T DE 69523044T DE 69523044 T DE69523044 T DE 69523044T DE 69523044 D1 DE69523044 D1 DE 69523044D1
- Authority
- DE
- Germany
- Prior art keywords
- polymer component
- treatment area
- sensitive polymer
- block
- graft copolymers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229920001400 block copolymer Polymers 0.000 title abstract 4
- 229920000578 graft copolymer Polymers 0.000 title abstract 4
- 229920000642 polymer Polymers 0.000 abstract 6
- 239000003814 drug Substances 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 230000036571 hydration Effects 0.000 abstract 2
- 238000006703 hydration reaction Methods 0.000 abstract 2
- 239000000017 hydrogel Substances 0.000 abstract 2
- 230000008961 swelling Effects 0.000 abstract 2
- 238000013270 controlled release Methods 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
- C08F265/02—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of acids, salts or anhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/45—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the shape
- A61F13/49—Absorbent articles specially adapted to be worn around the waist, e.g. diapers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/90—Block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/91—Graft copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/52—Amides or imides
- C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
- C08F220/56—Acrylamide; Methacrylamide
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
- C08F265/10—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of amides or imides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/54—Polymers characterized by specific structures/properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20571294A | 1994-03-04 | 1994-03-04 | |
PCT/US1995/002638 WO1995024430A2 (en) | 1994-03-04 | 1995-03-03 | Block and graft copolymers and methods relating thereto |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69523044D1 true DE69523044D1 (de) | 2001-11-08 |
DE69523044T2 DE69523044T2 (de) | 2002-06-20 |
Family
ID=22763329
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69523044T Expired - Fee Related DE69523044T2 (de) | 1994-03-04 | 1995-03-03 | Block- und pfropfcopolymere und dazu gehöriges verfahren |
Country Status (11)
Country | Link |
---|---|
US (1) | US6486213B1 (de) |
EP (1) | EP0748342B1 (de) |
JP (1) | JPH10500148A (de) |
KR (1) | KR970701739A (de) |
CN (1) | CN1145080A (de) |
AT (1) | ATE206441T1 (de) |
AU (1) | AU692852B2 (de) |
CA (1) | CA2184814A1 (de) |
DE (1) | DE69523044T2 (de) |
MX (1) | MX9603858A (de) |
WO (1) | WO1995024430A2 (de) |
Families Citing this family (119)
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US5843470A (en) | 1995-10-06 | 1998-12-01 | Mdv Technologies, Inc. | Method and composition for inhibiting post-surgical adhesions |
EP0986402A2 (de) | 1997-06-06 | 2000-03-22 | Battelle Memorial Institute | Reversibles gelbindendes copolymer und verfahren |
WO1999032151A1 (en) * | 1997-12-23 | 1999-07-01 | Alliance Pharmaceutical Corporation | Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions |
WO1999034831A1 (en) | 1998-01-05 | 1999-07-15 | University Of Washington | Enhanced transport using membrane disruptive agents |
DE19812688A1 (de) | 1998-03-23 | 1999-09-30 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
US6296831B1 (en) | 1998-04-10 | 2001-10-02 | Battelle Memorial Institute | Stimulus sensitive gel with radioisotope and methods of making |
US5968480A (en) * | 1998-07-09 | 1999-10-19 | Colgate Palmolive Company | Oral composition exhibiting enhanced antiplaque efficacy |
EP1109563A4 (de) | 1998-08-04 | 2009-07-22 | Madash Llp | Am ende modifizierte hydrogele mit temperaturabhängigen eigenschaften |
JP2002538949A (ja) | 1999-03-17 | 2002-11-19 | フォスター−ミラー・インコーポレーテッド | 反応性ゲル及びその使用方法 |
WO2001051092A2 (en) * | 2000-01-07 | 2001-07-19 | University Of Washington | Enhanced transport of agents using membrane disruptive agents |
US7160931B2 (en) | 2000-03-15 | 2007-01-09 | Yu-Ling Cheng | Thermally reversible implant and filler |
WO2001068768A1 (en) * | 2000-03-15 | 2001-09-20 | Cheng Yu Ling | Environment responsive gelling copolymer |
US7193007B2 (en) | 2000-03-15 | 2007-03-20 | Yu-Ling Cheng | Environment responsive gelling copolymer |
FR2811995B1 (fr) | 2000-07-21 | 2003-06-06 | Oreal | Polymere comprenant des unites hydrosolubles et des unites a lcst, et composition aqueuse le comprenant |
US7186419B2 (en) * | 2000-08-25 | 2007-03-06 | Contura Sa | Polyacrylamide hydrogel for arthritis |
MY130475A (en) | 2000-08-25 | 2007-06-29 | Contura As | Polyacrylamide hydrogel and its use as an endoprosthesis |
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FR2819416B1 (fr) | 2001-01-15 | 2004-12-17 | Oreal | Composition moussante tehrmogelifiante et mousse obtenue |
FR2819415B1 (fr) | 2001-01-15 | 2003-11-21 | Oreal | Dispersions stabilisees a des temperatures des 4 a 50 au moyen d'un polymere comportant des unites hydrosolubles et des unites a lcst |
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JP2003089752A (ja) * | 2001-03-23 | 2003-03-28 | Canon Inc | 刺激応答性ポリマーを含む組成物、それを含むインク組成物、並びに該インク組成物を用いた画像形成方法および装置 |
FR2823439A1 (fr) * | 2001-04-13 | 2002-10-18 | Oreal | Composition de bain gelifiantes, relaxantes |
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-
1995
- 1995-03-03 AT AT95913533T patent/ATE206441T1/de not_active IP Right Cessation
- 1995-03-03 DE DE69523044T patent/DE69523044T2/de not_active Expired - Fee Related
- 1995-03-03 KR KR1019960704956A patent/KR970701739A/ko not_active Application Discontinuation
- 1995-03-03 AU AU20932/95A patent/AU692852B2/en not_active Ceased
- 1995-03-03 EP EP95913533A patent/EP0748342B1/de not_active Expired - Lifetime
- 1995-03-03 JP JP7523531A patent/JPH10500148A/ja active Pending
- 1995-03-03 MX MX9603858A patent/MX9603858A/es unknown
- 1995-03-03 CN CN95192454A patent/CN1145080A/zh active Pending
- 1995-03-03 CA CA002184814A patent/CA2184814A1/en not_active Abandoned
- 1995-03-03 WO PCT/US1995/002638 patent/WO1995024430A2/en active IP Right Grant
- 1995-06-07 US US08/483,475 patent/US6486213B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2184814A1 (en) | 1995-09-14 |
EP0748342A1 (de) | 1996-12-18 |
AU2093295A (en) | 1995-09-25 |
KR970701739A (ko) | 1997-04-12 |
ATE206441T1 (de) | 2001-10-15 |
CN1145080A (zh) | 1997-03-12 |
MX9603858A (es) | 1997-12-31 |
DE69523044T2 (de) | 2002-06-20 |
JPH10500148A (ja) | 1998-01-06 |
EP0748342B1 (de) | 2001-10-04 |
WO1995024430A2 (en) | 1995-09-14 |
US6486213B1 (en) | 2002-11-26 |
WO1995024430A3 (en) | 1995-12-21 |
AU692852B2 (en) | 1998-06-18 |
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