DE69526108D1 - Zusammensetzungen enthaltend lazaroide und ihre verwendung zur vorbeugung von adhäsionen - Google Patents

Zusammensetzungen enthaltend lazaroide und ihre verwendung zur vorbeugung von adhäsionen

Info

Publication number
DE69526108D1
DE69526108D1 DE69526108T DE69526108T DE69526108D1 DE 69526108 D1 DE69526108 D1 DE 69526108D1 DE 69526108 T DE69526108 T DE 69526108T DE 69526108 T DE69526108 T DE 69526108T DE 69526108 D1 DE69526108 D1 DE 69526108D1
Authority
DE
Germany
Prior art keywords
compound
lazaroids
compositions containing
lipid
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69526108T
Other languages
English (en)
Other versions
DE69526108T2 (de
Inventor
E Rodgers
S Dizerega
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southern California USC
Original Assignee
University of Southern California USC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Southern California USC filed Critical University of Southern California USC
Publication of DE69526108D1 publication Critical patent/DE69526108D1/de
Application granted granted Critical
Publication of DE69526108T2 publication Critical patent/DE69526108T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
DE69526108T 1994-11-17 1995-11-15 Zusammensetzungen enthaltend lazaroide und ihre verwendung zur vorbeugung von adhäsionen Expired - Lifetime DE69526108T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/341,651 US5614515A (en) 1994-11-17 1994-11-17 Lazaroid-based compositions and method for preventing adhesion formation using the same
PCT/US1995/014938 WO1996015795A1 (en) 1994-11-17 1995-11-15 Compositions containing lazaroids and their use for preventing adhesions

Publications (2)

Publication Number Publication Date
DE69526108D1 true DE69526108D1 (de) 2002-05-02
DE69526108T2 DE69526108T2 (de) 2002-11-21

Family

ID=23338469

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526108T Expired - Lifetime DE69526108T2 (de) 1994-11-17 1995-11-15 Zusammensetzungen enthaltend lazaroide und ihre verwendung zur vorbeugung von adhäsionen

Country Status (9)

Country Link
US (1) US5614515A (de)
EP (1) EP0792153B1 (de)
JP (1) JPH10511645A (de)
AT (1) ATE214932T1 (de)
AU (1) AU692641B2 (de)
CA (2) CA2205347C (de)
DE (1) DE69526108T2 (de)
ES (1) ES2171203T3 (de)
WO (1) WO1996015795A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69507493T2 (de) * 1994-09-01 1999-06-10 Upjohn Co Tirilazad parentale formulierung mit einem co-lösungsmittel
US5866554A (en) * 1996-07-19 1999-02-02 Shalaby; Shalaby W. Compositions for prevention of inflammation and adhesion formation and uses thereof
US6515016B2 (en) * 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
ATE208218T1 (de) * 1997-04-22 2001-11-15 Hans Georg Graeber Membransystem zur gesteuerten geweberegeneration bei erkrankungen des zahnhalteapparates
AU3077299A (en) 1998-03-11 1999-09-27 University Of Southern California Method of promoting production of living tissue equivalents
DE69924715T2 (de) 1998-05-11 2006-01-26 University Of Southern California, Los Angeles Verwendung von angiotensin-analoga zur herstellung eines arzneimittels zur steigerung des ueberlebens von weissen blutzellen und mobilisierung von haematopoetischen stammzellen nach einer chemotherapeutischen behandlung
US6762167B1 (en) 1998-05-11 2004-07-13 University Of Southern California Methods for treating a patient undergoing chemotherapy
GB9810127D0 (en) 1998-05-13 1998-07-08 Ml Lab Plc Prevention of surgical adhesions
PL194109B1 (pl) * 1998-05-13 2007-04-30 Innovata Plc Kompozycja do zapobiegania albo zmniejszania występowania zrostów pooperacyjnych oraz jej zastosowanie
DE69911609T2 (de) 1998-07-13 2004-07-01 University Of Southern California, Los Angeles Verfahren zur beschleunigen den zuwachs und heilen von knochen und knorpel
US6916783B2 (en) 1998-07-13 2005-07-12 University Of Southern California Methods for accelerating bone and cartilage growth and repair
US6730775B1 (en) 1999-03-23 2004-05-04 University Of Southern California Methods for limiting scar and adhesion formation
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US7338938B2 (en) 1999-05-10 2008-03-04 University Of Southern California Methods for treating a patient undergoing chemotherapy
US6800298B1 (en) * 2000-05-11 2004-10-05 Clemson University Biological lubricant composition and method of applying lubricant composition
CN1537018A (zh) * 2001-05-23 2004-10-13 田边制药株式会社 一种用于软骨疾病再生治疗的组合物
KR20040007596A (ko) * 2001-05-23 2004-01-24 다나베 세이야꾸 가부시키가이샤 골절 치료 촉진용 조성물
WO2009114461A2 (en) * 2008-03-10 2009-09-17 University Of Southern California Angiotensin (1-7) dosage forms and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987001706A2 (en) * 1985-09-12 1987-03-26 The Upjohn Company C20 through c26 amino steroids
IN166447B (de) * 1985-11-27 1990-05-12 Ethicon Inc
US4968675A (en) * 1988-10-28 1990-11-06 Upjohn Non-hemolytic lazaroid parenteral formulation
US5256408A (en) * 1990-06-12 1993-10-26 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use

Also Published As

Publication number Publication date
AU692641B2 (en) 1998-06-11
CA2205347C (en) 2008-10-21
ATE214932T1 (de) 2002-04-15
ES2171203T3 (es) 2002-09-01
CA2625906A1 (en) 1996-05-30
US5614515A (en) 1997-03-25
WO1996015795A1 (en) 1996-05-30
CA2625906C (en) 2010-02-09
CA2205347A1 (en) 1996-05-30
JPH10511645A (ja) 1998-11-10
EP0792153B1 (de) 2002-03-27
EP0792153A1 (de) 1997-09-03
AU4110796A (en) 1996-06-17
DE69526108T2 (de) 2002-11-21

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803