DE69526225T2 - Zusammensetzung enthaltend morphin, polyvinylpyrrolidon und ein polyalkylenoxid - Google Patents

Zusammensetzung enthaltend morphin, polyvinylpyrrolidon und ein polyalkylenoxid

Info

Publication number
DE69526225T2
DE69526225T2 DE69526225T DE69526225T DE69526225T2 DE 69526225 T2 DE69526225 T2 DE 69526225T2 DE 69526225 T DE69526225 T DE 69526225T DE 69526225 T DE69526225 T DE 69526225T DE 69526225 T2 DE69526225 T2 DE 69526225T2
Authority
DE
Germany
Prior art keywords
morphine
polyvinylpyrrolidone
composition containing
polyalkylene oxide
containing morphine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69526225T
Other languages
English (en)
Other versions
DE69526225D1 (de
Inventor
Sonya Merrill
Atul Devdatt Ayer
Paul Hwang
Anthony L Kuczynski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of DE69526225D1 publication Critical patent/DE69526225D1/de
Application granted granted Critical
Publication of DE69526225T2 publication Critical patent/DE69526225T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
DE69526225T 1994-06-27 1995-06-14 Zusammensetzung enthaltend morphin, polyvinylpyrrolidon und ein polyalkylenoxid Expired - Fee Related DE69526225T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/266,075 US5460826A (en) 1994-06-27 1994-06-27 Morphine therapy
PCT/US1995/007727 WO1996000066A1 (en) 1994-06-27 1995-06-14 Composition comprising morphine, polypyrrolidone and a polyalkyleneoxide

Publications (2)

Publication Number Publication Date
DE69526225D1 DE69526225D1 (de) 2002-05-08
DE69526225T2 true DE69526225T2 (de) 2003-01-09

Family

ID=23013065

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526225T Expired - Fee Related DE69526225T2 (de) 1994-06-27 1995-06-14 Zusammensetzung enthaltend morphin, polyvinylpyrrolidon und ein polyalkylenoxid

Country Status (14)

Country Link
US (3) US5460826A (de)
EP (1) EP0767663B1 (de)
JP (1) JPH10502086A (de)
KR (1) KR100388880B1 (de)
AT (1) ATE215372T1 (de)
AU (1) AU688524B2 (de)
CA (1) CA2186260C (de)
DE (1) DE69526225T2 (de)
ES (1) ES2172587T3 (de)
FI (1) FI965203A (de)
MX (1) MX9700082A (de)
NO (1) NO311326B1 (de)
NZ (1) NZ288509A (de)
WO (1) WO1996000066A1 (de)

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Also Published As

Publication number Publication date
ATE215372T1 (de) 2002-04-15
FI965203A0 (fi) 1996-12-23
CA2186260C (en) 2007-07-31
NO311326B1 (no) 2001-11-19
FI965203A (fi) 1996-12-23
NO965540L (no) 1996-12-27
ES2172587T3 (es) 2002-10-01
WO1996000066A1 (en) 1996-01-04
US5667805A (en) 1997-09-16
KR100388880B1 (ko) 2003-09-19
AU2776195A (en) 1996-01-19
NO965540D0 (no) 1996-12-23
DE69526225D1 (de) 2002-05-08
KR970703769A (ko) 1997-08-09
NZ288509A (en) 1998-07-28
EP0767663A1 (de) 1997-04-16
AU688524B2 (en) 1998-03-12
MX9700082A (es) 1997-04-30
JPH10502086A (ja) 1998-02-24
EP0767663B1 (de) 2002-04-03
CA2186260A1 (en) 1996-01-04
US5460826A (en) 1995-10-24
US5593695A (en) 1997-01-14

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