DE69536051D1 - Vorrichtung und Verfahren zum In-vivo-Züchten von verschiedenen Gewebezellen - Google Patents

Vorrichtung und Verfahren zum In-vivo-Züchten von verschiedenen Gewebezellen

Info

Publication number
DE69536051D1
DE69536051D1 DE69536051T DE69536051T DE69536051D1 DE 69536051 D1 DE69536051 D1 DE 69536051D1 DE 69536051 T DE69536051 T DE 69536051T DE 69536051 T DE69536051 T DE 69536051T DE 69536051 D1 DE69536051 D1 DE 69536051D1
Authority
DE
Germany
Prior art keywords
vivo
tissue cells
various tissue
growing various
growing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69536051T
Other languages
English (en)
Inventor
John H Brekke
Timothy Ringeisen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Biomedical Inc
Original Assignee
Kensey Nash Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/367,510 external-priority patent/US5855608A/en
Application filed by Kensey Nash Corp filed Critical Kensey Nash Corp
Application granted granted Critical
Publication of DE69536051D1 publication Critical patent/DE69536051D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
DE69536051T 1994-05-13 1995-05-15 Vorrichtung und Verfahren zum In-vivo-Züchten von verschiedenen Gewebezellen Expired - Lifetime DE69536051D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/242,557 US5981825A (en) 1994-05-13 1994-05-13 Device and methods for in vivo culturing of diverse tissue cells
US08/367,510 US5855608A (en) 1994-05-13 1994-12-30 Device and methods for in vivo culturing of diverse tissue cells

Publications (1)

Publication Number Publication Date
DE69536051D1 true DE69536051D1 (de) 2010-04-08

Family

ID=22915268

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69536051T Expired - Lifetime DE69536051D1 (de) 1994-05-13 1995-05-15 Vorrichtung und Verfahren zum In-vivo-Züchten von verschiedenen Gewebezellen

Country Status (2)

Country Link
US (2) US5981825A (de)
DE (1) DE69536051D1 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7963997B2 (en) * 2002-07-19 2011-06-21 Kensey Nash Corporation Device for regeneration of articular cartilage and other tissue
US8795242B2 (en) * 1994-05-13 2014-08-05 Kensey Nash Corporation Resorbable polymeric device for localized drug delivery
US6528483B2 (en) 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
DE19803673A1 (de) 1998-01-30 1999-08-05 Norbert M Dr Meenen Biohybrider Gelenkflächenersatz
US6660301B1 (en) 1998-03-06 2003-12-09 Biosphere Medical, Inc. Injectable microspheres for dermal augmentation and tissue bulking
US6551355B1 (en) * 1998-08-14 2003-04-22 Cambridge Scientific, Inc. Tissue transplant coated with biocompatible biodegradable polymer
US20030114936A1 (en) * 1998-10-12 2003-06-19 Therics, Inc. Complex three-dimensional composite scaffold resistant to delimination
US6702821B2 (en) 2000-01-14 2004-03-09 The Bonutti 2003 Trust A Instrumentation for minimally invasive joint replacement and methods for using same
US7635390B1 (en) * 2000-01-14 2009-12-22 Marctec, Llc Joint replacement component having a modular articulating surface
ATE327783T1 (de) 2000-03-20 2006-06-15 Biosphere Medical Inc Injizierbare mikrokügelchen für den gewebeaufbau
EP1274472A2 (de) 2000-03-20 2003-01-15 Biosphere Medical, Inc. Injizierbare und schwellfähige mikrokügelchen zur gewebeverstärkung
US7338657B2 (en) * 2001-03-15 2008-03-04 Biosphere Medical, Inc. Injectable microspheres for tissue construction
US6436424B1 (en) * 2000-03-20 2002-08-20 Biosphere Medical, Inc. Injectable and swellable microspheres for dermal augmentation
US6719970B1 (en) 2000-07-10 2004-04-13 Alkermes Controlled Therapeutics, Inc. Method of generating cartilage
US6440141B1 (en) 2000-07-24 2002-08-27 Oratec Interventions, Inc. Method and apparatus for treating osteochondral pathologies
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
WO2002083194A1 (en) * 2001-04-12 2002-10-24 Therics, Inc. Method and apparatus for engineered regenerative biostructures
US20050177237A1 (en) * 2001-04-12 2005-08-11 Ben Shappley Spinal cage insert, filler piece and method of manufacturing
US20070038244A1 (en) * 2001-06-08 2007-02-15 Morris Edward J Method and apparatus for sealing access
US20060004408A1 (en) * 2001-06-08 2006-01-05 Morris Edward J Method and apparatus for sealing access
US7993365B2 (en) * 2001-06-08 2011-08-09 Morris Innovative, Inc. Method and apparatus for sealing access
EP1416888A4 (de) 2001-07-16 2007-04-25 Depuy Products Inc Vorrichtung und verfahren zur regeneration des meniskus
WO2003007790A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
EP1416886A4 (de) * 2001-07-16 2007-04-18 Depuy Products Inc Gerüst und verfahren für die knorpelreparatur und regeneration
AU2002313694B2 (en) * 2001-07-16 2007-08-30 Depuy Products, Inc. Cartilage repair apparatus and method
US7819918B2 (en) 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
EP1416866A4 (de) 2001-07-16 2007-04-18 Depuy Products Inc Vorrichtungen aus natürlich vorkommenden mitteln biologischer herkunft
US7201917B2 (en) 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
US7708741B1 (en) 2001-08-28 2010-05-04 Marctec, Llc Method of preparing bones for knee replacement surgery
CA2467252C (en) * 2001-10-25 2008-12-02 Japan Science And Technology Agency Composite biomaterials
US20040062753A1 (en) * 2002-09-27 2004-04-01 Alireza Rezania Composite scaffolds seeded with mammalian cells
WO2004037311A2 (en) 2002-10-21 2004-05-06 Kensey Nash Corporation Device and methods for sequential, regional delivery of multiple cytotoxic agents
US20050085922A1 (en) * 2003-10-17 2005-04-21 Shappley Ben R. Shaped filler for implantation into a bone void and methods of manufacture and use thereof
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US7513866B2 (en) 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US20060111778A1 (en) * 2004-10-29 2006-05-25 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
EP1883398A4 (de) * 2005-02-01 2012-06-06 Osteobiologics Inc Verfahren und vorrichtung zur selektiven zugabe eines bioaktiven wirkstoffes zu einem mehrphasenimplantat
US20070038299A1 (en) * 2005-08-12 2007-02-15 Arthrotek, Inc Multilayer microperforated implant
US20070148144A1 (en) * 2005-10-27 2007-06-28 Mason James M Gene-enhanced tissue engineering
US20090208586A1 (en) * 2006-03-20 2009-08-20 Jms. Co., Ltd. porous bioabsorbable material and method of producing the same
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20090024106A1 (en) * 2007-07-17 2009-01-22 Morris Edward J Method and apparatus for maintaining access
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
US8118832B1 (en) 2008-06-16 2012-02-21 Morris Innovative, Inc. Method and apparatus for sealing access
KR101016372B1 (ko) 2008-12-09 2011-02-21 이진호 선택적 투과성 및 골 점착성을 가지는 다공성 골유도재생막및 그 제조방법
US9744123B2 (en) * 2009-06-30 2017-08-29 Kensey Nash Corporation Biphasic implant device providing gradient
US20100331998A1 (en) * 2009-06-30 2010-12-30 Ringeisen Timothy A Electrokinetic device for tissue repair
US10016278B2 (en) * 2009-06-30 2018-07-10 Dsm Ip Assets B.V. Biphasic implant device providing joint fluid therapy
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
CN103313733A (zh) 2010-11-15 2013-09-18 捷迈整形外科生物材料有限公司 骨空隙填充剂
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
US10207027B2 (en) 2012-06-11 2019-02-19 Globus Medical, Inc. Bioactive bone graft substitutes
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
US9539286B2 (en) 2013-10-18 2017-01-10 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
US9486483B2 (en) 2013-10-18 2016-11-08 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
US9579421B2 (en) 2014-02-07 2017-02-28 Globus Medical Inc. Bone grafts and methods of making and using bone grafts
US9463264B2 (en) 2014-02-11 2016-10-11 Globus Medical, Inc. Bone grafts and methods of making and using bone grafts
US11426489B2 (en) 2015-06-10 2022-08-30 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
US10016529B2 (en) 2015-06-10 2018-07-10 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
US11896736B2 (en) 2020-07-13 2024-02-13 Globus Medical, Inc Biomaterial implants and methods of making the same

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2465357A (en) * 1944-08-14 1949-03-29 Upjohn Co Therapeutic sponge and method of making
US2610625A (en) * 1947-10-14 1952-09-16 Armour & Co Surgical sponge and the preparation thereof
US2621145A (en) * 1949-08-17 1952-12-09 Machteld E Sano Bone mat compositions
US2703316A (en) * 1951-06-05 1955-03-01 Du Pont Polymers of high melting lactide
US2758987A (en) * 1952-06-05 1956-08-14 Du Pont Optically active homopolymers containing but one antipodal species of an alpha-monohydroxy monocarboxylic acid
US3463158A (en) * 1963-10-31 1969-08-26 American Cyanamid Co Polyglycolic acid prosthetic devices
US3739773A (en) * 1963-10-31 1973-06-19 American Cyanamid Co Polyglycolic acid prosthetic devices
GB1147072A (en) * 1965-07-09 1969-04-02 Braun Internat Gmbh B Process for preparing a wound covering
US4419340A (en) * 1969-03-24 1983-12-06 University Of Delaware Controlled release of anticancer agents from biodegradable polymers
BE758156R (fr) * 1970-05-13 1971-04-28 Ethicon Inc Element de suture absorbable et sa
US3688317A (en) * 1970-08-25 1972-09-05 Sutures Inc Vascular prosthetic
US3902497A (en) * 1974-03-25 1975-09-02 American Cyanamid Co Body absorbable sponge and method of making
US3937223A (en) * 1974-04-19 1976-02-10 American Cyanamid Company Compacted surgical hemostatic felt
US4186448A (en) * 1976-04-16 1980-02-05 Brekke John H Device and method for treating and healing a newly created bone void
US4164560A (en) * 1977-01-05 1979-08-14 Folkman Moses J Systems for the controlled release of macromolecules
US4181983A (en) * 1977-08-29 1980-01-08 Kulkarni R K Assimilable hydrophilic prosthesis
FR2439003A1 (fr) * 1978-10-20 1980-05-16 Anvar Nouvelles pieces d'osteosynthese, leur preparation et leur application
US4553272A (en) * 1981-02-26 1985-11-19 University Of Pittsburgh Regeneration of living tissues by growth of isolated cells in porous implant and product thereof
US4442655A (en) * 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
US4357312A (en) * 1981-07-16 1982-11-02 The Children's Hospital Medical Center Method of making prolonged release body
US4505266A (en) * 1981-10-26 1985-03-19 Massachusetts Institute Of Technology Method of using a fibrous lattice
IL68218A (en) * 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
US4578384A (en) * 1984-02-15 1986-03-25 The United States Of America As Represented By The Secretary Of The Army Polylactic-polyglycolic acids combined with an acidic phospholipid-lysozyme complex for healing osseous tissue
US4609551A (en) * 1984-03-20 1986-09-02 Arnold Caplan Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites
US4608199A (en) * 1984-03-20 1986-08-26 Arnold Caplan Bone protein purification process
DE3414924A1 (de) * 1984-04-19 1985-10-31 Klaus Dr.med. Dr.med.habil. 8000 München Draenert Beschichtetes verankerungsteil fuer implantate
US4596574A (en) * 1984-05-14 1986-06-24 The Regents Of The University Of California Biodegradable porous ceramic delivery system for bone morphogenetic protein
US4620327A (en) * 1984-07-05 1986-11-04 Caplan Arnold I Process of adapting soluble bone protein for use in stimulating osteoinduction
NL8402178A (nl) * 1984-07-10 1986-02-03 Rijksuniversiteit Entstuk, geschikt voor behandeling door reconstructieve chirurgie van beschadigingen van beenachtig materiaal.
DK153828C (da) * 1984-09-05 1989-02-06 Mayo Odense V Faltum & Soenner Skaalformet beholder med markeringsmidler, isaer til opbevaring af foedevare
US4563350A (en) * 1984-10-24 1986-01-07 Collagen Corporation Inductive collagen based bone repair preparations
SE450623B (sv) * 1984-11-07 1987-07-13 Dan Lundgren Element for kontrollerad vevnadsinvext i kirurgiskt intervenerade omraden
US4636526A (en) * 1985-02-19 1987-01-13 The Dow Chemical Company Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics
US4627853A (en) * 1985-05-29 1986-12-09 American Hospital Supply Corporation Method of producing prostheses for replacement of articular cartilage and prostheses so produced
US4964868A (en) * 1985-07-25 1990-10-23 Harrington Arthritis Research Center Knee prosthesis
US5061281A (en) * 1985-12-17 1991-10-29 Allied-Signal Inc. Bioresorbable polymers and implantation devices thereof
US5133755A (en) * 1986-01-28 1992-07-28 Thm Biomedical, Inc. Method and apparatus for diodegradable, osteogenic, bone graft substitute device
US4749585A (en) * 1986-04-11 1988-06-07 University Of Medicine And Dentistry Of New Jersey Antibiotic bonded prosthesis and process for producing same
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
CA1274179A (en) * 1986-04-30 1990-09-18 Patricia D'amore Bioerodible articles useful as implants and prostheses having predictable degradation rates
US4962091A (en) * 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
CA1340581C (en) * 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
US5041138A (en) * 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
NL8700113A (nl) * 1987-01-19 1988-08-16 Groningen Science Park Entstuk, geschikt voor behandeling door reconstructieve chirurgie, met weefsel specifieke porositeit, alsmede werkwijze ter vervaardiging van het entstuk.
JPH0773601B2 (ja) 1987-03-27 1995-08-09 柳沢 定勝 生体の補填補綴材料
US4846835A (en) * 1987-06-15 1989-07-11 Grande Daniel A Technique for healing lesions in cartilage
US5078744A (en) * 1987-09-04 1992-01-07 Bio-Products, Inc. Method of using tendon/ligament substitutes composed of long, parallel, non-antigenic tendon/ligament fibers
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
JP2820415B2 (ja) * 1988-03-14 1998-11-05 ティーエイチエム・バイオメディカル・インコーポレイテッド 生分解性および骨形成性を有する移植骨片代用組成体
JP2706467B2 (ja) * 1988-05-27 1998-01-28 住友大阪セメント株式会社 骨移植用人工骨構造体
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
DE3841397A1 (de) * 1988-12-08 1990-06-21 Melzer Wolfgang Poroeser resorbierbarer arzneistofftraeger
WO1990009783A1 (en) * 1989-02-22 1990-09-07 Massachusetts Institute Of Technology Delivery system for controlled release of bioactive factors
US5376118A (en) * 1989-05-10 1994-12-27 United States Surgical Corporation Support material for cell impregnation
CA2056384C (en) * 1989-06-05 1998-06-23 Tobin N. Gerhart Bioerodible polymers for drug delivery in bone
JP2805086B2 (ja) 1989-06-20 1998-09-30 グンゼ株式会社 生体組織用充填材
US5324519A (en) * 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5077049A (en) * 1989-07-24 1991-12-31 Vipont Pharmaceutical, Inc. Biodegradable system for regenerating the periodontium
WO1991001720A1 (en) * 1989-08-07 1991-02-21 Herman Wade Schlameus Composition and method of promoting hard tissue healing
US5152791A (en) * 1989-12-07 1992-10-06 Olympus Optical Co., Ltd. Prosthetic artificial bone having ceramic layers of different porosity
US5288496A (en) * 1990-05-15 1994-02-22 Stolle Research & Development Corporation Growth promoters for animals
AU7998091A (en) * 1990-05-17 1991-12-10 Harbor Medical Devices, Inc. Medical device polymer
JP3007903B2 (ja) * 1991-03-29 2000-02-14 京セラ株式会社 人工椎間板
US5356429A (en) * 1991-05-16 1994-10-18 Seare William J Jr Body pocket maintenance prosthesis
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
CA2117379C (en) * 1992-02-14 1999-11-16 Kypriacos A. Athanasiou Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5326357A (en) * 1992-03-18 1994-07-05 Mount Sinai Hospital Corporation Reconstituted cartridge tissue
WO1993020859A1 (en) * 1992-04-20 1993-10-28 Board Of Regents Of The University Of Washington Sustained release compositions for delivery of growth factors
CA2093836A1 (en) * 1992-04-24 1993-10-25 Wayne Gombotz Biodegradable tgf-.beta. delivery system for bone regeneration
US5478739A (en) * 1992-10-23 1995-12-26 Advanced Tissue Sciences, Inc. Three-dimensional stromal cell and tissue culture system
US5447725A (en) * 1993-06-11 1995-09-05 The Procter & Gamble Company Methods for aiding periodontal tissue regeneration
US5736160A (en) 1993-10-28 1998-04-07 Thm Biomedical, Inc. Process and device for treating and healing a bone void
US5425639A (en) * 1994-05-03 1995-06-20 Anders; Irving Dental implant with shock absorbent cushioned interface
US5665114A (en) * 1994-08-12 1997-09-09 Meadox Medicals, Inc. Tubular expanded polytetrafluoroethylene implantable prostheses
US5520923A (en) * 1994-09-19 1996-05-28 Genetics Institute, Inc. Formulations for delivery of osteogenic proteins
TW369414B (en) * 1994-09-30 1999-09-11 Yamanouchi Pharma Co Ltd Bone formation transplant
US5645084A (en) * 1995-06-07 1997-07-08 Danek Medical, Inc. Method for spinal fusion without decortication

Also Published As

Publication number Publication date
US6264701B1 (en) 2001-07-24
US5981825A (en) 1999-11-09

Similar Documents

Publication Publication Date Title
DE69536051D1 (de) Vorrichtung und Verfahren zum In-vivo-Züchten von verschiedenen Gewebezellen
DE69829336D1 (de) Vorrichtung und Verfahren zur Behandlung von Körpergewebe
DE69524278T2 (de) Verfahren und Vorrichtung zum Querschneiden
DE69535992D1 (de) Verfahren zum Fixieren von kultiviertem Gewebe und fixierte Kunsthaut
DE69519604D1 (de) Verfahren und Vorrichtung zum Herstellen von Tabletten
DE69730109D1 (de) Verfahren und Vorrichtung zum Herstellen von Wasserzeichen
DE69515381T2 (de) Verfahren und Vorrichtung zum Herstellen von Tabletten
DE59809751D1 (de) Verfahren und Vorrichtung zum Herstellen von Packungen
DE69529342T2 (de) Verfahren und vorrichtung zum herstellen von kurbelwellen
DE69724886D1 (de) Verfahren und Vorrichtung zum Kristallziehen
DE69401932D1 (de) Verfahren zum behandeln von tabak und vorrichtung für das verfahren
DE69534698D1 (de) Verfahren und Vorrichtung zum Vermittlen von Zellen
DE69719181D1 (de) Aufgerollte taschen und verfahren und vorrichtung zum herstellen von endlos aufgerollten taschen
DE59506572D1 (de) Vorrichtung und Verfahren zum Herstellen von Rohren
DE69418177D1 (de) Verfahren und Vorrichtung zum Herstellen von Dünnfilmen
DE69821825D1 (de) Vorrichtung und Verfahren zum Sterilisieren
DE69503633T2 (de) Verfahren und vorrichtung für das kristallwachstum
ATA194694A (de) Verfahren und vorrichtung zum herstellen von hohlbausteinen
DE69729237D1 (de) Verfahren und Vorrichtung zum Herstellen von Laminaten
DE69621106T2 (de) Verfahren und Vorrichtung zum Herstellen von Rakeln für elektrophotographische Geräte
DE69501694T2 (de) Vorrichtung und Verfahren zum Sterilisieren von Lebensmitteln
DE59700775D1 (de) Verfahren und Vorrichtung zur elektrolytischen Behandlung von durchlaufendem Gut
DE59804600D1 (de) Verfahren und vorrichtung zum herstellen von schraubverbindungen
DE59704132D1 (de) Verfahren und vorrichtung zum gefrieren von zellsuspensionen
DE69716967T2 (de) Verfahren zum herstellen von heftchen und die vorrichtung dafür

Legal Events

Date Code Title Description
8364 No opposition during term of opposition