DE69601637T2 - Nichttrennender chemilumineszenzassay durch spezifische bindung - Google Patents
Nichttrennender chemilumineszenzassay durch spezifische bindungInfo
- Publication number
- DE69601637T2 DE69601637T2 DE69601637T DE69601637T DE69601637T2 DE 69601637 T2 DE69601637 T2 DE 69601637T2 DE 69601637 T DE69601637 T DE 69601637T DE 69601637 T DE69601637 T DE 69601637T DE 69601637 T2 DE69601637 T2 DE 69601637T2
- Authority
- DE
- Germany
- Prior art keywords
- solid phase
- tracer
- specific binding
- analyte
- bound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/496,549 US5783453A (en) | 1995-06-29 | 1995-06-29 | Non-separation specific binding chemiluminescent assay |
PCT/IB1996/000617 WO1997001763A1 (en) | 1995-06-29 | 1996-06-27 | Non-separation specific binding chemiluminescent assay |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69601637D1 DE69601637D1 (de) | 1999-04-08 |
DE69601637T2 true DE69601637T2 (de) | 1999-09-16 |
Family
ID=23973125
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69601637T Expired - Fee Related DE69601637T2 (de) | 1995-06-29 | 1996-06-27 | Nichttrennender chemilumineszenzassay durch spezifische bindung |
Country Status (11)
Country | Link |
---|---|
US (1) | US5783453A (de) |
EP (1) | EP0835451B1 (de) |
JP (1) | JPH11508682A (de) |
KR (1) | KR19990028561A (de) |
AT (1) | ATE177208T1 (de) |
AU (1) | AU700057B2 (de) |
BR (1) | BR9609390A (de) |
CA (1) | CA2224825A1 (de) |
DE (1) | DE69601637T2 (de) |
PL (1) | PL324312A1 (de) |
WO (1) | WO1997001763A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6087088A (en) * | 1997-01-31 | 2000-07-11 | Bayer Corporation | Binding assays using more than one label for determining analyte in the presence of interfering factors |
US6146836A (en) * | 1997-05-19 | 2000-11-14 | Bayer Corporation | Immunoassays using anti-allotypic monoclonal antibodies |
US6056923A (en) * | 1997-06-25 | 2000-05-02 | Clmp, Inc. | Dual injector for chemiluminescence immunoanalyzing system |
DE69940433D1 (de) * | 1998-08-11 | 2009-04-02 | Siemens Healthcare Diagnostics | Im nahen infrarot chemilumineszente akridinium derivate und ihre verwendung |
GB2359625B (en) * | 1999-12-10 | 2004-10-20 | Molecular Light Tech Res Ltd | Monitoring oligonucleotide binding process using chemiluminescence quenching |
AU2001293232A1 (en) * | 2000-08-29 | 2002-03-13 | The Rockefeller University | Methods employing fluorescence quenching by metal surfaces |
US6723851B2 (en) | 2001-10-31 | 2004-04-20 | Quest Diagnostics Investment Incorporated | Chemiluminescent compounds and use thereof |
US20090196852A1 (en) * | 2008-02-04 | 2009-08-06 | Watkinson D Tobin | Compositions and methods for diagnosing and treating immune disorders |
JP5539958B2 (ja) * | 2008-04-02 | 2014-07-02 | アボット ポイント オブ ケア インコーポレイテッド | 薄膜状体液試料において実施される血清学的凝集イムノアッセイ及び他のイムノアッセイのための方法 |
CN107478824A (zh) * | 2017-08-11 | 2017-12-15 | 太原瑞盛生物科技有限公司 | 一种莱克多巴胺的磁微粒化学发光检测试剂盒及制备方法 |
CN107356746A (zh) * | 2017-08-23 | 2017-11-17 | 太原瑞盛生物科技有限公司 | 一种特布他林的磁微粒化学发光检测试剂盒及制备方法 |
CN107478827A (zh) * | 2017-08-23 | 2017-12-15 | 太原瑞盛生物科技有限公司 | 一种伏马毒素的化学发光检测试剂盒及其制备方法 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3352791A (en) * | 1965-01-22 | 1967-11-14 | American Cyanamid Co | Generation of light by the reaction of peroxide with heterocyclic derivatives |
US3689391A (en) * | 1970-05-13 | 1972-09-05 | Synvar Ass | Method for chemically initiating photochemical reactions |
US4277437A (en) * | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
US4576912A (en) * | 1978-11-30 | 1986-03-18 | Technicon Instruments Corporation | Fluoroimmunoassaying |
IL64574A (en) * | 1981-04-27 | 1986-01-31 | Syva Co | Method for determining the presence of an analyte by determination of the amount of fluorescence in competitive protein binding assays |
FI63596C (fi) * | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
GB2129553B (en) * | 1982-09-10 | 1986-06-18 | Welsh Nat School Med | Immunological procedure for detecting or quantifying substances |
DE3310337A1 (de) * | 1983-03-22 | 1984-09-27 | Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg | Verfahren zur durchfuehrung von hybridisierungsreaktionen |
US4695392A (en) * | 1983-05-12 | 1987-09-22 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
US4554088A (en) * | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
US4698302A (en) * | 1983-05-12 | 1987-10-06 | Advanced Magnetics, Inc. | Enzymatic reactions using magnetic particles |
US4628037A (en) * | 1983-05-12 | 1986-12-09 | Advanced Magnetics, Inc. | Binding assays employing magnetic particles |
US4695393A (en) * | 1983-05-12 | 1987-09-22 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
US4672040A (en) * | 1983-05-12 | 1987-06-09 | Advanced Magnetics, Inc. | Magnetic particles for use in separations |
JPS61217766A (ja) * | 1985-03-23 | 1986-09-27 | Tadashi Hara | 蛋白質の定量方法および定量装置 |
US5017473A (en) * | 1987-05-26 | 1991-05-21 | Becton, Dickinson And Company | Homogeneous chemiluminescence immunoassay using a light absorbing material |
US4927769A (en) * | 1987-07-08 | 1990-05-22 | Ciba Corning Diagnostics Corp. | Method for enhancement of chemiluminescence |
EP0638807B1 (de) * | 1987-09-21 | 2002-07-17 | Gen-Probe Incorporated | Schutztest |
PT88665B (pt) * | 1987-10-05 | 1992-12-31 | Ml Tecnology Ventures Lp | Metodo para a marcacao com ester de acridinio e purificacao de sondas nucleotidicas |
US5321136A (en) * | 1987-12-31 | 1994-06-14 | London Diagnostics, Inc. | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom |
US5241070A (en) * | 1988-09-26 | 1993-08-31 | Ciba Corning Diagnostics Corp. | Nucleophilic polysubstituted aryl acridinium esters and uses thereof |
US5093270A (en) * | 1989-05-24 | 1992-03-03 | Ciba Corning Diagnostics Corp. | Method for enhancing signal release from liposomes using water-miscible alcohols |
CA2028012A1 (en) * | 1989-10-23 | 1991-04-24 | Randall Dimond | Hybridization assay for campylobacter rrna |
EP0476545B1 (de) * | 1990-09-14 | 1997-05-07 | Tosoh Corporation | Verfahren und Kit für Immunoassay |
CA2046713A1 (en) * | 1990-10-16 | 1992-04-17 | Richard M. Martinelli | Amplification of midivariant dna templates |
DE69233146T2 (de) * | 1991-05-22 | 2004-04-29 | Dade Behring Marburg Gmbh | Partikel, die eine Zusammensetzung beinhalten, die eine chemilumineszierende Verbindung umfassen |
ATE184320T1 (de) * | 1991-07-10 | 1999-09-15 | Igen Int Inc | Verfahren für verbesserte lumineszenz-assays unter verwendung von teilchenkonzentration und chemilumineszenznachweis |
US5395752A (en) * | 1993-03-19 | 1995-03-07 | Ciba Corning Diagnostics Corp. | Long emission wavelength chemiluminescent compounds and their use in test assays |
-
1995
- 1995-06-29 US US08/496,549 patent/US5783453A/en not_active Expired - Fee Related
-
1996
- 1996-06-27 EP EP96917616A patent/EP0835451B1/de not_active Expired - Lifetime
- 1996-06-27 JP JP9504283A patent/JPH11508682A/ja active Pending
- 1996-06-27 KR KR1019970709881A patent/KR19990028561A/ko not_active Application Discontinuation
- 1996-06-27 AT AT96917616T patent/ATE177208T1/de not_active IP Right Cessation
- 1996-06-27 WO PCT/IB1996/000617 patent/WO1997001763A1/en not_active Application Discontinuation
- 1996-06-27 PL PL96324312A patent/PL324312A1/xx unknown
- 1996-06-27 CA CA002224825A patent/CA2224825A1/en not_active Abandoned
- 1996-06-27 AU AU60133/96A patent/AU700057B2/en not_active Ceased
- 1996-06-27 BR BR9609390A patent/BR9609390A/pt not_active Application Discontinuation
- 1996-06-27 DE DE69601637T patent/DE69601637T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR19990028561A (ko) | 1999-04-15 |
AU700057B2 (en) | 1998-12-17 |
BR9609390A (pt) | 1999-05-18 |
EP0835451A1 (de) | 1998-04-15 |
CA2224825A1 (en) | 1997-01-16 |
US5783453A (en) | 1998-07-21 |
JPH11508682A (ja) | 1999-07-27 |
PL324312A1 (en) | 1998-05-25 |
ATE177208T1 (de) | 1999-03-15 |
MX9710410A (es) | 1998-07-31 |
WO1997001763A1 (en) | 1997-01-16 |
EP0835451B1 (de) | 1999-03-03 |
DE69601637D1 (de) | 1999-04-08 |
AU6013396A (en) | 1997-01-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |