DE69604600T2 - Neue Zuckerbeschichtungszusammensetzung zum Auftragen auf komprimierte Wirkstofftabletten - Google Patents

Neue Zuckerbeschichtungszusammensetzung zum Auftragen auf komprimierte Wirkstofftabletten

Info

Publication number
DE69604600T2
DE69604600T2 DE69604600T DE69604600T DE69604600T2 DE 69604600 T2 DE69604600 T2 DE 69604600T2 DE 69604600 T DE69604600 T DE 69604600T DE 69604600 T DE69604600 T DE 69604600T DE 69604600 T2 DE69604600 T2 DE 69604600T2
Authority
DE
Germany
Prior art keywords
application
coating composition
sugar coating
new sugar
active tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69604600T
Other languages
English (en)
Other versions
DE69604600D1 (de
Inventor
Reginald Joseph Barcomb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23473354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69604600(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of DE69604600D1 publication Critical patent/DE69604600D1/de
Publication of DE69604600T2 publication Critical patent/DE69604600T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
DE69604600T 1995-01-17 1996-01-15 Neue Zuckerbeschichtungszusammensetzung zum Auftragen auf komprimierte Wirkstofftabletten Expired - Lifetime DE69604600T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/373,667 US5547948A (en) 1995-01-17 1995-01-17 Controlled release of steroids from sugar coatings

Publications (2)

Publication Number Publication Date
DE69604600D1 DE69604600D1 (de) 1999-11-18
DE69604600T2 true DE69604600T2 (de) 2000-02-24

Family

ID=23473354

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69604600T Expired - Lifetime DE69604600T2 (de) 1995-01-17 1996-01-15 Neue Zuckerbeschichtungszusammensetzung zum Auftragen auf komprimierte Wirkstofftabletten

Country Status (35)

Country Link
US (2) US5547948A (de)
EP (1) EP0722720B1 (de)
JP (1) JP3833292B2 (de)
KR (1) KR100338581B1 (de)
CN (1) CN1106839C (de)
AR (1) AR002019A1 (de)
AT (1) ATE185482T1 (de)
AU (1) AU705879B2 (de)
BR (1) BR9600100B1 (de)
CA (1) CA2167254A1 (de)
CO (1) CO4370096A1 (de)
CZ (1) CZ286102B6 (de)
DE (1) DE69604600T2 (de)
DK (1) DK0722720T3 (de)
EE (1) EE03802B1 (de)
EG (1) EG23687A (de)
ES (1) ES2137627T3 (de)
FI (1) FI117592B (de)
GR (1) GR3031920T3 (de)
HK (1) HK1009935A1 (de)
HU (1) HU223781B1 (de)
ID (1) ID23996A (de)
IL (1) IL116772A (de)
IS (1) IS1878B (de)
MY (1) MY115786A (de)
NO (1) NO315307B1 (de)
NZ (1) NZ280826A (de)
PL (1) PL183330B1 (de)
RU (1) RU2152207C1 (de)
SI (1) SI0722720T1 (de)
SK (1) SK280484B6 (de)
TR (1) TR199600038A2 (de)
TW (1) TW460301B (de)
UA (1) UA37236C2 (de)
ZA (1) ZA96301B (de)

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Also Published As

Publication number Publication date
HU223781B1 (hu) 2005-01-28
CZ286102B6 (cs) 2000-01-12
IL116772A0 (en) 1996-05-14
US5547948A (en) 1996-08-20
JP3833292B2 (ja) 2006-10-11
DE69604600D1 (de) 1999-11-18
CN1106839C (zh) 2003-04-30
EP0722720A1 (de) 1996-07-24
IS1878B (is) 2003-06-20
FI117592B (fi) 2006-12-15
FI960210A0 (fi) 1996-01-16
TW460301B (en) 2001-10-21
EP0722720B1 (de) 1999-10-13
NO960191L (no) 1996-07-18
ID23996A (id) 1996-07-25
IL116772A (en) 1999-08-17
US5759576A (en) 1998-06-02
AU4098296A (en) 1996-07-25
SK280484B6 (sk) 2000-02-14
AR002019A1 (es) 1998-01-07
UA37236C2 (uk) 2001-05-15
SK4996A3 (en) 1997-04-09
HUP9600090A3 (en) 1997-05-28
CA2167254A1 (en) 1996-07-18
KR960028919A (ko) 1996-08-17
HK1009935A1 (en) 1999-06-11
IS4318A (is) 1996-07-18
DK0722720T3 (da) 2000-01-03
GR3031920T3 (en) 2000-03-31
KR100338581B1 (ko) 2002-11-23
NO960191D0 (no) 1996-01-16
PL183330B1 (pl) 2002-06-28
PL312336A1 (en) 1996-07-22
NZ280826A (en) 1996-12-20
EE03802B1 (et) 2002-08-15
MY115786A (en) 2003-09-30
NO315307B1 (no) 2003-08-18
ZA96301B (en) 1997-07-15
CO4370096A1 (es) 1996-10-07
TR199600038A2 (tr) 1996-08-21
FI960210A (fi) 1996-07-18
EG23687A (en) 2007-05-13
RU2152207C1 (ru) 2000-07-10
CN1141168A (zh) 1997-01-29
CZ12896A3 (en) 1996-08-14
ES2137627T3 (es) 1999-12-16
AU705879B2 (en) 1999-06-03
HUP9600090A2 (en) 1996-12-30
ATE185482T1 (de) 1999-10-15
JPH08231436A (ja) 1996-09-10
BR9600100B1 (pt) 2009-01-13
BR9600100A (pt) 1998-01-27
SI0722720T1 (en) 1999-12-31
EE9600002A (et) 1996-08-15

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Owner name: WYETH (N.D.GES.D. STAATES DELAWARE), MADISON, N.J.