DE69609084T2 - Verfahren zur behandlung von verletzungen retinaler ganglione mit neurotrophischem faktor aus der glialzellinie (gdnf) - Google Patents

Verfahren zur behandlung von verletzungen retinaler ganglione mit neurotrophischem faktor aus der glialzellinie (gdnf)

Info

Publication number
DE69609084T2
DE69609084T2 DE69609084T DE69609084T DE69609084T2 DE 69609084 T2 DE69609084 T2 DE 69609084T2 DE 69609084 T DE69609084 T DE 69609084T DE 69609084 T DE69609084 T DE 69609084T DE 69609084 T2 DE69609084 T2 DE 69609084T2
Authority
DE
Germany
Prior art keywords
gdnf
cell line
neurotrophic factor
glial cell
treating injuries
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69609084T
Other languages
English (en)
Other versions
DE69609084D1 (de
Inventor
Qiao Yang
Jean-Claude Marcel Louis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of DE69609084D1 publication Critical patent/DE69609084D1/de
Application granted granted Critical
Publication of DE69609084T2 publication Critical patent/DE69609084T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
DE69609084T 1995-11-29 1996-11-22 Verfahren zur behandlung von verletzungen retinaler ganglione mit neurotrophischem faktor aus der glialzellinie (gdnf) Expired - Lifetime DE69609084T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/564,458 US5641749A (en) 1995-11-29 1995-11-29 Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product
PCT/US1996/018851 WO1997019695A1 (en) 1995-11-29 1996-11-22 Method for treating retinal ganglion cell injury using glial cell line-derived neurotrophic factor (gdnf) protein product

Publications (2)

Publication Number Publication Date
DE69609084D1 DE69609084D1 (de) 2000-08-03
DE69609084T2 true DE69609084T2 (de) 2000-11-16

Family

ID=24254557

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69609084T Expired - Lifetime DE69609084T2 (de) 1995-11-29 1996-11-22 Verfahren zur behandlung von verletzungen retinaler ganglione mit neurotrophischem faktor aus der glialzellinie (gdnf)

Country Status (20)

Country Link
US (1) US5641749A (de)
EP (1) EP0866719B1 (de)
JP (1) JP4066201B2 (de)
KR (1) KR19990071541A (de)
CN (1) CN1203531A (de)
AT (1) ATE194081T1 (de)
BR (1) BR9611748A (de)
CA (1) CA2236158C (de)
CZ (1) CZ149998A3 (de)
DE (1) DE69609084T2 (de)
DK (1) DK0866719T3 (de)
ES (1) ES2148826T3 (de)
GR (1) GR3034194T3 (de)
HU (1) HUP0001078A2 (de)
IL (1) IL124600A0 (de)
MX (1) MX9803968A (de)
NO (1) NO982276L (de)
PT (1) PT866719E (de)
SK (1) SK65898A3 (de)
WO (1) WO1997019695A1 (de)

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Also Published As

Publication number Publication date
ATE194081T1 (de) 2000-07-15
ES2148826T3 (es) 2000-10-16
IL124600A0 (en) 1998-12-06
CA2236158A1 (en) 1997-06-05
DE69609084D1 (de) 2000-08-03
PT866719E (pt) 2000-11-30
BR9611748A (pt) 1999-06-01
EP0866719B1 (de) 2000-06-28
KR19990071541A (ko) 1999-09-27
HUP0001078A2 (hu) 2000-08-28
MX9803968A (es) 1998-09-30
NO982276D0 (no) 1998-05-19
DK0866719T3 (da) 2000-08-28
EP0866719A1 (de) 1998-09-30
US5641749A (en) 1997-06-24
JP2000501393A (ja) 2000-02-08
SK65898A3 (en) 1999-01-11
CA2236158C (en) 2002-07-16
CZ149998A3 (cs) 1998-08-12
WO1997019695A1 (en) 1997-06-05
AU1163197A (en) 1997-06-19
NO982276L (no) 1998-07-29
GR3034194T3 (en) 2000-11-30
AU696772B2 (en) 1998-09-17
JP4066201B2 (ja) 2008-03-26
CN1203531A (zh) 1998-12-30

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