DE69620182D1 - Polymere lamellare substratpartikel zur arzneistoffverabreichung - Google Patents

Polymere lamellare substratpartikel zur arzneistoffverabreichung

Info

Publication number
DE69620182D1
DE69620182D1 DE69620182T DE69620182T DE69620182D1 DE 69620182 D1 DE69620182 D1 DE 69620182D1 DE 69620182 T DE69620182 T DE 69620182T DE 69620182 T DE69620182 T DE 69620182T DE 69620182 D1 DE69620182 D1 DE 69620182D1
Authority
DE
Germany
Prior art keywords
pct
particles
administration
medicinal products
substrate particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69620182T
Other languages
English (en)
Other versions
DE69620182T2 (de
Inventor
Gerald Coombes
Stewart Davis
Lisa Major
Michael Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NOTTINGHAM NOTTINGHAM GB, University of
Original Assignee
West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd filed Critical West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd
Application granted granted Critical
Publication of DE69620182D1 publication Critical patent/DE69620182D1/de
Publication of DE69620182T2 publication Critical patent/DE69620182T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/795—Composed of biological material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/895—Manufacture, treatment, or detection of nanostructure having step or means utilizing chemical property
    • Y10S977/896—Chemical synthesis, e.g. chemical bonding or breaking
    • Y10S977/897—Polymerization
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y10S977/917—Vaccine
DE69620182T 1995-07-13 1996-07-15 Polymere lamellare substratpartikel zur arzneistoffverabreichung Expired - Fee Related DE69620182T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514285.7A GB9514285D0 (en) 1995-07-13 1995-07-13 Polymeric lamellar substrate particles for drug delivery
PCT/GB1996/001695 WO1997002810A2 (en) 1995-07-13 1996-07-15 Polymeric lamellar substrate particles for drug delivery

Publications (2)

Publication Number Publication Date
DE69620182D1 true DE69620182D1 (de) 2002-05-02
DE69620182T2 DE69620182T2 (de) 2003-01-16

Family

ID=10777561

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69620182T Expired - Fee Related DE69620182T2 (de) 1995-07-13 1996-07-15 Polymere lamellare substratpartikel zur arzneistoffverabreichung

Country Status (13)

Country Link
US (1) US6001395A (de)
EP (1) EP0837673B1 (de)
JP (1) JPH11508912A (de)
AT (1) ATE214918T1 (de)
AU (1) AU709031B2 (de)
CA (1) CA2223884A1 (de)
DE (1) DE69620182T2 (de)
DK (1) DK0837673T3 (de)
ES (1) ES2175109T3 (de)
GB (1) GB9514285D0 (de)
NO (1) NO315406B1 (de)
PT (1) PT837673E (de)
WO (1) WO1997002810A2 (de)

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WO2000006123A1 (en) * 1998-07-29 2000-02-10 Chiron Corporation Microparticles with adsorbent surfaces, methods of making same, and uses thereof
US6884435B1 (en) 1997-01-30 2005-04-26 Chiron Corporation Microparticles with adsorbent surfaces, methods of making same, and uses thereof
EP1275380A1 (de) * 1997-01-30 2003-01-15 Chiron Corporation Verwendung von Mikropartikeln mit adsorbiertem Antigen zur Stimulierung der Immunabwehr
US7135191B2 (en) * 1997-09-04 2006-11-14 Zsolt Istvan Hertelendy Urogenital or anorectal transmucosal vaccine delivery system
GB9722682D0 (en) * 1997-10-27 1997-12-24 Scherer Ltd R P Pharmaceutical products
US20030059471A1 (en) * 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
DE69804671T2 (de) 1997-12-16 2002-11-21 Chiron Corp Verwendung von mikropartikeln mit submikron öl/wasser emulsionen
US7393630B2 (en) * 1997-12-16 2008-07-01 Novartis Vaccines And Diagnostics, Inc. Use of microparticles combined with submicron oil-in-water emulsions
SE9801288D0 (sv) * 1998-04-14 1998-04-14 Astra Ab Vaccine delivery system and metod of production
ES2243082T3 (es) 1998-10-01 2005-11-16 Powderject Research Limited Microparticulas con revestimiento aplicado por pulverizacion utilizadaen una jeringa sin aguja.
FR2786098B1 (fr) 1998-11-20 2003-05-30 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
US6365173B1 (en) 1999-01-14 2002-04-02 Efrat Biopolymers Ltd. Stereocomplex polymeric carriers for drug delivery
EP1156812A4 (de) * 1999-02-23 2004-09-29 Isis Pharmaceuticals Inc Multipartikuläre formulierung
ES2242604T3 (es) 1999-02-26 2005-11-16 Chiron Corporation Microemulsiones con macroparticulas y microparticulas adsorbidas.
GB9905136D0 (en) 1999-03-06 1999-04-28 Danbiosyst Uk Surface modification of lamellar particles
US20050214227A1 (en) * 1999-03-08 2005-09-29 Powderject Research Limited Microparticle formulations for sustained-release of bioactive compounds
US7713739B1 (en) 2000-11-17 2010-05-11 Novartis Vaccines And Diagnostics, Inc. Microparticle-based transfection and activation of dendritic cells
FR2801226B1 (fr) 1999-11-23 2002-01-25 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation
FR2814952B1 (fr) 2000-10-06 2004-01-02 Flamel Tech Sa Suspension colloidale de particules submicromiques de vectorisation de principes actifs et leur mode de preparation
WO2002019989A2 (en) * 2000-09-08 2002-03-14 Powderject Research Limited Alginate particle formulation
JP2004509914A (ja) 2000-09-28 2004-04-02 カイロン　コーポレイション 微粒子組成物およびその製造方法
US7266687B2 (en) * 2001-02-16 2007-09-04 Motorola, Inc. Method and apparatus for storing and distributing encryption keys
ES2607431T3 (es) * 2002-02-20 2017-03-31 Glaxosmithkline Biologicals Sa Micropartículas con moléculas que contienen polipéptidos adsorbidos
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
US7285289B2 (en) * 2002-04-12 2007-10-23 Nagy Jon O Nanoparticle vaccines
JP2003342196A (ja) * 2002-05-31 2003-12-03 Mukku:Kk 静脈注射用組成物、その製造法およびその製剤
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
US7649023B2 (en) 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
CN1780555A (zh) * 2003-05-01 2006-05-31 韦斯特制药服务药物输送和临床研究中心有限公司 Lh－rh类似物亮丙瑞林的鼻部给药
CA2528007C (en) 2003-06-02 2012-03-27 Chiron Corporation Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen
FR2859909B1 (fr) 2003-09-22 2007-09-07 Biomerieux Sa Procede de preparation de microparticules bioresorbables, microparticules obtenues et utilisation
US20060263350A1 (en) * 2003-09-26 2006-11-23 Fairfield Clinical Trials Llc Combination antihistamine medication
JP5026956B2 (ja) * 2004-05-12 2012-09-19 サーモディクス，インコーポレイティド 医療用具のための天然生分解性多糖コーティング
CA2621657C (en) * 2005-09-21 2014-06-17 Surmodics, Inc. In situ occluding compositions comprising natural biodegradable polysaccharides polymerized by a redox pair
US20070065483A1 (en) * 2005-09-21 2007-03-22 Chudzik Stephen J In vivo formed matrices including natural biodegradable polysaccharides and uses thereof
JP5806444B2 (ja) 2005-12-02 2015-11-10 ノバルティス アーゲー 免疫原性組成物で使用するためのナノ粒子
CN103494661B (zh) * 2006-07-20 2016-03-30 奥巴斯尼茨医学公司 可生物吸收的聚合物医疗器械
EP3009477B1 (de) 2006-07-20 2024-01-24 Orbusneich Medical Pte. Ltd Bioresorbierbare polymerzusammensetzung für eine medizinische vorrichtung
US8460364B2 (en) * 2006-07-20 2013-06-11 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
EP2073754A4 (de) * 2006-10-20 2012-09-26 Orbusneich Medical Inc Bioresorbierbare polymerzusammensetzung und hintergrund für eine medizinische vorrichtung
US7959942B2 (en) * 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
US20090246155A1 (en) * 2006-12-05 2009-10-01 Landec Corporation Compositions and methods for personal care
US8399007B2 (en) * 2006-12-05 2013-03-19 Landec Corporation Method for formulating a controlled-release pharmaceutical formulation
EP2500015A1 (de) * 2006-12-05 2012-09-19 Landec Corporation Verabreichung von Arzneimitteln
US20090263346A1 (en) * 2006-12-05 2009-10-22 David Taft Systems and methods for delivery of drugs
US20100004124A1 (en) * 2006-12-05 2010-01-07 David Taft Systems and methods for delivery of materials for agriculture and aquaculture
WO2008073295A2 (en) * 2006-12-07 2008-06-19 Surmodics, Inc. Latent stabilization of bioactive agents releasable from implantable medical articles
US20110130822A1 (en) * 2007-07-20 2011-06-02 Orbusneich Medical, Inc. Bioabsorbable Polymeric Compositions and Medical Devices
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Also Published As

Publication number Publication date
DK0837673T3 (da) 2002-07-22
US6001395A (en) 1999-12-14
NO315406B1 (no) 2003-09-01
WO1997002810A3 (en) 1997-02-20
ATE214918T1 (de) 2002-04-15
PT837673E (pt) 2002-09-30
AU709031B2 (en) 1999-08-19
WO1997002810A2 (en) 1997-01-30
EP0837673A2 (de) 1998-04-29
AU6466596A (en) 1997-02-10
EP0837673B1 (de) 2002-03-27
CA2223884A1 (en) 1997-01-30
NO976018L (no) 1997-12-22
ES2175109T3 (es) 2002-11-16
DE69620182T2 (de) 2003-01-16
JPH11508912A (ja) 1999-08-03
GB9514285D0 (en) 1995-09-13
NO976018D0 (no) 1997-12-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: THE UNIVERSITY OF NOTTINGHAM, NOTTINGHAM, GB

8339 Ceased/non-payment of the annual fee