DE69620791D1 - Verfahren zur auswertung polymorpher genetischer sequenzen, und dessen gebrauch zur bestimmung von hla-typen - Google Patents

Verfahren zur auswertung polymorpher genetischer sequenzen, und dessen gebrauch zur bestimmung von hla-typen

Info

Publication number
DE69620791D1
DE69620791D1 DE69620791T DE69620791T DE69620791D1 DE 69620791 D1 DE69620791 D1 DE 69620791D1 DE 69620791 T DE69620791 T DE 69620791T DE 69620791 T DE69620791 T DE 69620791T DE 69620791 D1 DE69620791 D1 DE 69620791D1
Authority
DE
Germany
Prior art keywords
evaluating
genetic sequences
hla types
polymorphic genetic
determining hla
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69620791T
Other languages
English (en)
Other versions
DE69620791T2 (de
Inventor
K Stevens
M Dunn
James Leushner
J Green
Chris Toronto Gabe
D Gilchrist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
Original Assignee
Visible Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visible Genetics Inc filed Critical Visible Genetics Inc
Application granted granted Critical
Publication of DE69620791D1 publication Critical patent/DE69620791D1/de
Publication of DE69620791T2 publication Critical patent/DE69620791T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
DE69620791T 1995-12-22 1996-12-19 Verfahren zur auswertung polymorpher genetischer sequenzen, und dessen gebrauch zur bestimmung von hla-typen Expired - Lifetime DE69620791T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/577,858 US5834189A (en) 1994-07-08 1995-12-22 Method for evaluation of polymorphic genetic sequences, and the use thereof in identification of HLA types
PCT/US1996/020202 WO1997023650A2 (en) 1995-12-22 1996-12-19 Method for evaluation of polymorphic genetic sequences, and the use thereof in identification of hla types

Publications (2)

Publication Number Publication Date
DE69620791D1 true DE69620791D1 (de) 2002-05-23
DE69620791T2 DE69620791T2 (de) 2002-08-14

Family

ID=24310433

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69620791T Expired - Lifetime DE69620791T2 (de) 1995-12-22 1996-12-19 Verfahren zur auswertung polymorpher genetischer sequenzen, und dessen gebrauch zur bestimmung von hla-typen

Country Status (7)

Country Link
US (1) US5834189A (de)
EP (1) EP0870059B1 (de)
JP (1) JP2000502260A (de)
AU (1) AU718670B2 (de)
CA (1) CA2239896C (de)
DE (1) DE69620791T2 (de)
WO (1) WO1997023650A2 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830655A (en) 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US6007983A (en) * 1995-12-22 1999-12-28 Visible Genetics Inc. Method and kit for evaluation of HIV mutations
US6265152B1 (en) 1995-12-22 2001-07-24 Visible Genetics Inc. Method and kit for evaluation of HIV mutations
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
US6830887B2 (en) 1997-03-18 2004-12-14 Bayer Healthcare Llc Method and kit for quantitation and nucleic acid sequencing of nucleic acid analytes in a sample
JP2001518313A (ja) * 1997-09-26 2001-10-16 ビジブル ジェネティクス インコーポレイテッド Ｈｉｖ突然変異の評価方法およびキット
EP0953650A1 (de) 1998-04-20 1999-11-03 Innogenetics N.V. Verfahren für die HLA Typisierung
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6379957B1 (en) * 1998-09-21 2002-04-30 Leslie A. Johnston-Dow Methods for HIV sequencing and genotyping
US6703228B1 (en) 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
EP1001037A3 (de) * 1998-09-28 2003-10-01 Whitehead Institute For Biomedical Research Vorselektion und Isolierung eines Einzelnukleotidpolymorphismus
AU1543000A (en) * 1998-12-11 2000-07-03 Visible Genetics Inc. Method and kit for the characterization of antibiotic-resistance mutations in (mycobacterium) tuberculosis
EP1173610B1 (de) * 1999-04-09 2010-08-25 Innogenetics N.V. Methode zur amplifizierung von hla klasse i allelen
US6573047B1 (en) 1999-04-13 2003-06-03 Dna Sciences, Inc. Detection of nucleotide sequence variation through fluorescence resonance energy transfer label generation
US7655443B1 (en) * 1999-05-07 2010-02-02 Siemens Healthcare Diagnostics, Inc. Nucleic acid sequencing with simultaneous quantitation
US7058517B1 (en) 1999-06-25 2006-06-06 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
DE00941722T1 (de) * 1999-06-25 2004-04-15 Genaissance Pharmaceuticals Inc., New Haven Verfahren für erhaltung und anwendung von haplotype daten
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
US6406854B1 (en) * 1999-09-16 2002-06-18 Mj Research Method and compositions for evaluating resolution of nucleic acid separation systems
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
US6458544B1 (en) 1999-12-02 2002-10-01 Dna Sciences, Inc. Methods for determining single nucleotide variations and genotyping
US20010049102A1 (en) * 2000-02-24 2001-12-06 Huang Xiaohua C. Methods for determining single nucleotide variations
US6760668B1 (en) 2000-03-24 2004-07-06 Bayer Healthcare Llc Method for alignment of DNA sequences with enhanced accuracy and read length
US6931326B1 (en) 2000-06-26 2005-08-16 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
US6397150B1 (en) 2000-07-27 2002-05-28 Visible Genetics Inc. Method and apparatus for sequencing of DNA using an internal calibrant
GB0021286D0 (en) * 2000-08-30 2000-10-18 Gemini Genomics Ab Identification of drug metabolic capacity
CA2387277C (en) 2001-05-25 2015-03-03 Hitachi, Ltd. Information processing system using nucleotide sequence-related information
US7222059B2 (en) * 2001-11-15 2007-05-22 Siemens Medical Solutions Diagnostics Electrophoretic trace simulator
US20040267458A1 (en) * 2001-12-21 2004-12-30 Judson Richard S. Methods for obtaining and using haplotype data
EP1501863A4 (de) * 2002-05-03 2007-01-24 Sequenom Inc Kinaseankerproteinmuteine, peptide davon und damit im zusammenhang stehende verfahren
US20030220844A1 (en) * 2002-05-24 2003-11-27 Marnellos Georgios E. Method and system for purchasing genetic data
EP1396962A1 (de) * 2002-08-05 2004-03-10 Sony International (Europe) GmbH Busdienstschnittstelle
EP2112229A3 (de) 2002-11-25 2009-12-02 Sequenom, Inc. Verfahren zum Identifizieren des Brustkrebsrisikos und zugehörige Behandlungen
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
EP2248911A1 (de) 2004-02-19 2010-11-10 Helicos Biosciences Corporation Verfahren und Zusammensetzungen zur Analyse von Polynukleotidsequenzen
GB0406864D0 (en) 2004-03-26 2004-04-28 Qiagen As Nucleic acid sequencing
CA2574610A1 (en) * 2004-07-22 2006-03-02 Sequenom, Inc. Methods for identifying risk of type ii diabetes and treatments thereof
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
US20070065860A1 (en) * 2005-09-20 2007-03-22 Hildebrand William H Accelerated class I and class II HLA DNA sequence-based typing
US20070207490A1 (en) * 2006-03-06 2007-09-06 Applera Corporation Method and system for generating sample plate layout for validation
WO2007140417A2 (en) 2006-05-31 2007-12-06 Sequenom, Inc. Methods and compositions for the extraction and amplification of nucleic acid from a sample
US8153369B2 (en) 2006-06-05 2012-04-10 Cancer Care Ontario Assessment of risk for colorectal cancer
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
AU2008213634B2 (en) 2007-02-08 2013-09-05 Sequenom, Inc. Nucleic acid-based tests for RhD typing, gender determination and nucleic acid quantification
CA2679954A1 (en) 2007-03-05 2008-09-12 Cancer Care Ontario Assessment of risk for colorectal cancer
AU2008230813B2 (en) 2007-03-26 2014-01-30 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
EP2195452B1 (de) 2007-08-29 2012-03-14 Sequenom, Inc. Verfahren und zusammensetzungen für die universelle grössenspezifische polymerasekettenreaktion
WO2009114543A2 (en) 2008-03-11 2009-09-17 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
AU2009228312B2 (en) 2008-03-26 2015-05-21 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
EP2379748A4 (de) * 2008-12-23 2012-08-29 Illumina Inc Multibase-freisetzung für lange auslesevorgänge bei squenzierungen mittels syntheseprotokollen
EP2396661A4 (de) 2009-02-11 2013-10-30 Caris Mpi Inc Molekulare profilierung von tumoren
EP3211095B1 (de) 2009-04-03 2019-01-02 Sequenom, Inc. Zusammensetzungen und verfahren für die herstellung von nukleinsäuren
GB0916013D0 (en) 2009-09-11 2009-10-28 King S College London Method
US20160186266A1 (en) 2009-10-27 2016-06-30 Carislife Sciences, Inc. Molecular profiling for personalized medicine
US9926593B2 (en) 2009-12-22 2018-03-27 Sequenom, Inc. Processes and kits for identifying aneuploidy
WO2012149339A2 (en) 2011-04-29 2012-11-01 Sequenom, Inc. Quantification of a minority nucleic acid species
ES2930180T3 (es) 2012-03-02 2022-12-07 Sequenom Inc Métodos para enriquecer ácido nucleico canceroso a partir de una muestra biológica
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
CA2878979C (en) 2012-07-13 2021-09-14 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US9896728B2 (en) 2013-01-29 2018-02-20 Arcticrx Ltd. Method for determining a therapeutic approach for the treatment of age-related macular degeneration (AMD)
EP3597774A1 (de) 2013-03-13 2020-01-22 Sequenom, Inc. Primer zur analyse der dna-methylierung
MX367192B (es) 2013-10-30 2019-08-08 Green Life Biotech Llc Sistemas de cuantificacion de patogenesis y metodos de tratamiento para el enverdecimiento de los citricos.
EP3736344A1 (de) 2014-03-13 2020-11-11 Sequenom, Inc. Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen
AU2019389175A1 (en) 2018-11-30 2021-06-10 Caris Mpi, Inc. Next-generation molecular profiling
EP4069865A4 (de) 2019-12-02 2023-12-20 Caris MPI, Inc. Platinresistenztest für pan-krebs

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582788A (en) * 1982-01-22 1986-04-15 Cetus Corporation HLA typing method and cDNA probes used therein
US5171534A (en) * 1984-01-16 1992-12-15 California Institute Of Technology Automated DNA sequencing technique
US5207880A (en) * 1984-03-29 1993-05-04 The Board Of Regents Of The University Of Nebraska DNA sequencing
US4865968A (en) * 1985-04-01 1989-09-12 The Salk Institute For Biological Studies DNA sequencing
US4811218A (en) * 1986-06-02 1989-03-07 Applied Biosystems, Inc. Real time scanning electrophoresis apparatus for DNA sequencing
US4971903A (en) * 1988-03-25 1990-11-20 Edward Hyman Pyrophosphate-based method and apparatus for sequencing nucleic acids
US4962020A (en) * 1988-07-12 1990-10-09 President And Fellows Of Harvard College DNA sequencing
DE3841565C2 (de) * 1988-12-09 1998-07-09 Europ Lab Molekularbiolog Verfahren zur Sequenzierung von Nukleinsäuren
US5547839A (en) * 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US5119316A (en) * 1990-06-29 1992-06-02 E. I. Du Pont De Nemours And Company Method for determining dna sequences
CA2105585A1 (en) * 1991-03-06 1992-09-07 Pedro Santamaria Dna sequence-based hla typing method
US5424184A (en) * 1991-05-08 1995-06-13 Regents Of The University Of Minnesota DNA sequence-based HLA class I typing method
US5365455A (en) * 1991-09-20 1994-11-15 Vanderbilt University Method and apparatus for automatic nucleic acid sequence determination
CA2081582A1 (en) * 1991-11-05 1993-05-06 Teodorica Bugawan Methods and reagents for hla class i dna typing
DE592060T1 (de) * 1992-10-09 1994-12-08 Univ Nebraska Digitale DNS-Typisierung.

Also Published As

Publication number Publication date
AU718670B2 (en) 2000-04-20
AU1426297A (en) 1997-07-17
JP2000502260A (ja) 2000-02-29
WO1997023650A3 (en) 1997-08-21
EP0870059A2 (de) 1998-10-14
US5834189A (en) 1998-11-10
CA2239896A1 (en) 1997-07-03
EP0870059B1 (de) 2002-04-17
WO1997023650A2 (en) 1997-07-03
CA2239896C (en) 2004-11-30
DE69620791T2 (de) 2002-08-14

Similar Documents

Publication Publication Date Title
DE69620791T2 (de) Verfahren zur auswertung polymorpher genetischer sequenzen, und dessen gebrauch zur bestimmung von hla-typen
DE69706430D1 (de) Verfahren zur sequenzierung von dna
DE69939070D1 (de) Verfahren zur quantifizierung von menschlicher wachsamkeit
DE69606794T2 (de) System und Verfahren zur Ermittlung von ähnlichen Zeitsequenzen in Datenbanken
DE69816789D1 (de) Verfahren und system zur gestengesteuerten optionsauswahl
DE69530277T2 (de) Verfahren zur auswahl von übertragungsvorzügen
DE69535554D1 (de) Lumineszente lanthanidenchelate und verfahren zu ihrer verwendung
DE69839778D1 (de) Widerstand und verfahren zu seiner herstellung
DE59609524D1 (de) Verfahren zur Genexpressionsanalyse
DE69719966T2 (de) Verfahren zur gleichzeitigen erkennung von verschiedenen fluorophoren in der in-situ hybridisierung
DE69831519D1 (de) System und Verfahren zur Lageermittlung
DE69739854D1 (de) System und verfahren zur bestimmung von spannungen
DE69624729D1 (de) Verfahren zur selektiven öffnung von naphtalinringen
DE69717413D1 (de) Verfahren zur Gewichtsbestimmung von bogenförmigen Trägern
DE69727395D1 (de) Verfahren zur olefinisomerisierung
DE69822685D1 (de) Verfahren zur Bestimmung von Nukleinsäuresequenzen
DE69602534T2 (de) Verfahren zur verwendung von metallocenkatalysatoren
DE59806044D1 (de) Verfahren zur ermittlung von segmentzeiten
DE69730268D1 (de) Verfahren und System zur Bestimmung von Farbmittelmengen
DE69837575D1 (de) Vorrichtung und Verfahren zur Inkubation von Teststreifen
ATE250472T1 (de) Vorrichtung und verfahren zur herstellung von stahlband
DE69613964D1 (de) Verfahren zur herstellung von pentafluoroethan und tetrafluorochloroethan
DE69839353D1 (de) Stahldraht und verfahren zu dessen herstellung
DE69629021D1 (de) Verfahren und anordnung zur vorhersage von diastrophismus
DE69501893D1 (de) Verfahren zur genetischen prüfung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BAYER HEALTHCARE, LLC, TARRYTOWN, N.Y., US

8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC. (N.D.GES.D, US

8328 Change in the person/name/address of the agent

Representative=s name: MAIER, D., DIPL.-ING. UNIV., PAT.-ASS., 81739 MUEN