DE69623303T2 - Pufferzusammensetzung fur immunologische reagenzien - Google Patents
Pufferzusammensetzung fur immunologische reagenzienInfo
- Publication number
- DE69623303T2 DE69623303T2 DE69623303T DE69623303T DE69623303T2 DE 69623303 T2 DE69623303 T2 DE 69623303T2 DE 69623303 T DE69623303 T DE 69623303T DE 69623303 T DE69623303 T DE 69623303T DE 69623303 T2 DE69623303 T2 DE 69623303T2
- Authority
- DE
- Germany
- Prior art keywords
- composition
- buffer composition
- buffer
- immunological reagents
- biological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 239000000872 buffer Substances 0.000 title abstract 2
- 230000001900 immune effect Effects 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000006177 biological buffer Substances 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000004034 viscosity adjusting agent Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/82—Hepatitis associated antigens and antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/482,710 US5616460A (en) | 1995-06-07 | 1995-06-07 | Buffer composition for reagents for immunoassay |
PCT/US1996/007745 WO1996041164A1 (en) | 1995-06-07 | 1996-05-24 | Buffer composition for reagents for immunoassay |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69623303D1 DE69623303D1 (de) | 2002-10-02 |
DE69623303T2 true DE69623303T2 (de) | 2003-04-17 |
Family
ID=23917128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69623303T Expired - Fee Related DE69623303T2 (de) | 1995-06-07 | 1996-05-24 | Pufferzusammensetzung fur immunologische reagenzien |
Country Status (7)
Country | Link |
---|---|
US (2) | US5616460A (de) |
EP (1) | EP0852009B1 (de) |
JP (2) | JP4101874B2 (de) |
AT (1) | ATE223046T1 (de) |
DE (1) | DE69623303T2 (de) |
ES (1) | ES2184866T3 (de) |
WO (1) | WO1996041164A1 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6171586B1 (en) | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
AU740284B2 (en) * | 1997-06-13 | 2001-11-01 | Genentech Inc. | Stabilized antibody formulation |
US6991790B1 (en) | 1997-06-13 | 2006-01-31 | Genentech, Inc. | Antibody formulation |
US6261764B1 (en) | 1997-09-22 | 2001-07-17 | Chiron Corporation | Buffers for stabilizing antigens |
US6391540B1 (en) | 1997-09-22 | 2002-05-21 | Chiron Corporation | Method for detecting antibodies in a sample |
WO1999054735A1 (en) * | 1998-04-17 | 1999-10-28 | Innogenetics N.V. | Improved immunodiagnostic assays using reducing agents |
CN1274424A (zh) * | 1998-07-30 | 2000-11-22 | 株式会社先端生命科学研究所 | 丙型肝炎病毒的测定方法 |
US6623921B2 (en) | 1998-07-30 | 2003-09-23 | Advanced Life Science Institute, Inc. | Method for measurement of hepatitis C virus |
DE10013794A1 (de) * | 2000-03-15 | 2001-10-11 | Gluesenkamp Karl Heinz | Herstellung, Stabilisierung und Anwendung einer neuen Art von chemisch aktivierten Oberflächen |
WO2002008761A1 (en) * | 2000-07-21 | 2002-01-31 | Cuno Incorporated | Improved blocking chemistries for nylon membrane |
CA2419295A1 (en) * | 2000-08-21 | 2002-02-28 | Queen's University At Kingston | Methods and kits for separation and detection of proteins in biological samples |
US20030170618A1 (en) * | 2001-02-02 | 2003-09-11 | Chien David Y. | Buffers for stabilizing antigens |
AR033448A1 (es) * | 2001-03-28 | 2003-12-17 | Ortho Clinical Diagnostics Inc | Prueba de combinacion antigeno-anticuerpo para hepatitis c para una deteccion temprana de la infeccion |
JP2003066047A (ja) * | 2001-06-14 | 2003-03-05 | Matsushita Electric Ind Co Ltd | 免疫反応測定方法及びそれに用いる免疫反応測定用試薬 |
US7101683B2 (en) | 2001-06-26 | 2006-09-05 | Abbott Laboratories | Methods for the simultaneous detection of HCV antigens and HCV antibodies |
CH698246B1 (de) * | 2001-12-20 | 2009-06-30 | Hoffmann La Roche | Test zur Identifizierung von Inhibitoren von Beta-Sekretasen. |
US20030157556A1 (en) * | 2002-02-13 | 2003-08-21 | Maggiore Jack A. | Biological fluid stabilizing composition and method of use thereof |
US7083912B2 (en) * | 2002-05-31 | 2006-08-01 | Penn State Research Foundation | MAb-based Dot-ELISA method and assay kit for the detection of viruses |
US20040152070A1 (en) * | 2003-02-04 | 2004-08-05 | Shah Dinesh O. | Method of detection of HCV antibodies in combination assay or sole antibody assay |
US20050014136A1 (en) * | 2003-05-28 | 2005-01-20 | Innogenetics N.V. | Modified HCV NS5 |
KR100830723B1 (ko) * | 2003-10-28 | 2008-05-20 | 가부시끼가이샤 센단세메이가가꾸겐큐죠 | C형 간염 바이러스의 검출 방법 |
CN104090097B (zh) * | 2004-02-26 | 2017-04-12 | 康多尔生物技术有限公司 | 一种用作结合对的特异性结合反应培养基的水溶液 |
CN1922487A (zh) | 2004-02-26 | 2007-02-28 | 康多尔生物技术有限公司 | 一种用作结合对的特异性结合反应培养基的水溶液 |
US7867443B2 (en) * | 2004-07-23 | 2011-01-11 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
US20080108147A1 (en) * | 2006-11-03 | 2008-05-08 | Tie Wei | Reduction of non-specific binding in immunoassays |
JP2007084579A (ja) * | 2006-12-28 | 2007-04-05 | Mitsubishi Pharma Corp | ヘパリン溶液入りプレフィルドシリンジ製剤およびその製造方法 |
US8617820B2 (en) * | 2007-08-28 | 2013-12-31 | Ortho-Clinical Diagnostics, Inc. | Use of glycosaminoglycans to reduce non-specific binding in immunoassays |
JP5416159B2 (ja) * | 2011-03-31 | 2014-02-12 | 富士フイルム株式会社 | 高感度なイムノクロマトグラフ方法 |
CN103630690B (zh) * | 2013-12-17 | 2014-08-20 | 朱之炜 | 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法 |
EP3258270B1 (de) * | 2015-02-10 | 2019-05-29 | Shenzhen New Industries Biomedical Engineering Co. Ltd. | Ultrasensitives reagenzienkit zum nachweis von kardialem troponin i und ultraempfindliches nachweisverfahren dafür |
CN114200125B (zh) * | 2021-12-06 | 2024-02-13 | 武汉生之源生物科技股份有限公司 | 一种不含蛋白的碱性磷酸酶-抗体偶联物稀释液及其制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59198999A (ja) * | 1983-04-27 | 1984-11-10 | Denka Seiken Co Ltd | クレアチンキナ−ゼ測定用組成物 |
JPS6339582A (ja) * | 1986-08-04 | 1988-02-20 | Takara Shuzo Co Ltd | 酵素組成物 |
US4956274A (en) * | 1987-04-06 | 1990-09-11 | Microgenics Corporation | Reagent stabilization in enzyme-donor and acceptor assay |
US5075221A (en) * | 1988-10-07 | 1991-12-24 | Eastman Kodak Company | Stabilized extraction composition containing a sulfhydryl-containing reducing agent and its use in chlamydial and gonococcal determinations |
WO1990006127A1 (en) * | 1988-12-06 | 1990-06-14 | Otsuka Pharmaceutical Co., Ltd. | STABILIZED COMPOSITION OF INTERLEUKIN-1$g(b) |
DK0527815T3 (da) * | 1990-04-06 | 2000-11-06 | Genelabs Tech Inc | Hepatitis C-virus-epitop |
WO1993006247A1 (en) * | 1991-09-16 | 1993-04-01 | Abbott Laboratories | Hepatitis c assay |
US5376313A (en) * | 1992-03-27 | 1994-12-27 | Abbott Laboratories | Injection molding a plastic assay cuvette having low birefringence |
GR1001480B (el) * | 1992-12-29 | 1994-02-28 | Eyaggelia Protopapa | Ενζυμικά σκευάσματα περιέχοντα παπαϊνη ή χυμο?ρυψίνη και μέ?οδοι μόνιμης ενζυμικής αποτρίχωσης. |
-
1995
- 1995-06-07 US US08/482,710 patent/US5616460A/en not_active Expired - Lifetime
-
1996
- 1996-05-24 WO PCT/US1996/007745 patent/WO1996041164A1/en active IP Right Grant
- 1996-05-24 EP EP96916655A patent/EP0852009B1/de not_active Expired - Lifetime
- 1996-05-24 DE DE69623303T patent/DE69623303T2/de not_active Expired - Fee Related
- 1996-05-24 JP JP50073897A patent/JP4101874B2/ja not_active Expired - Lifetime
- 1996-05-24 AT AT96916655T patent/ATE223046T1/de not_active IP Right Cessation
- 1996-05-24 ES ES96916655T patent/ES2184866T3/es not_active Expired - Lifetime
- 1996-10-16 US US08/734,435 patent/US5773212A/en not_active Expired - Fee Related
-
2005
- 2005-05-12 JP JP2005139663A patent/JP3930519B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2005300552A (ja) | 2005-10-27 |
US5616460A (en) | 1997-04-01 |
JP4101874B2 (ja) | 2008-06-18 |
JP2001516440A (ja) | 2001-09-25 |
ATE223046T1 (de) | 2002-09-15 |
EP0852009B1 (de) | 2002-08-28 |
WO1996041164A1 (en) | 1996-12-19 |
ES2184866T3 (es) | 2003-04-16 |
US5773212A (en) | 1998-06-30 |
EP0852009A1 (de) | 1998-07-08 |
JP3930519B2 (ja) | 2007-06-13 |
DE69623303D1 (de) | 2002-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |