DE69633668D1 - Allogene zelltherapie für krebs infolge allogener stammzellen transplantation - Google Patents
Allogene zelltherapie für krebs infolge allogener stammzellen transplantationInfo
- Publication number
- DE69633668D1 DE69633668D1 DE69633668T DE69633668T DE69633668D1 DE 69633668 D1 DE69633668 D1 DE 69633668D1 DE 69633668 T DE69633668 T DE 69633668T DE 69633668 T DE69633668 T DE 69633668T DE 69633668 D1 DE69633668 D1 DE 69633668D1
- Authority
- DE
- Germany
- Prior art keywords
- allogenic
- consequent
- cancer
- stem cell
- cell therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 238000002659 cell therapy Methods 0.000 title 1
- 238000011476 stem cell transplantation Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46434—Antigens related to induction of tolerance to non-self
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/26—Universal/off- the- shelf cellular immunotherapy; Allogenic cells or means to avoid rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/49—Breast
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44976495A | 1995-05-25 | 1995-05-25 | |
US449764 | 1995-05-25 | ||
PCT/US1996/007652 WO1996037208A1 (en) | 1995-05-25 | 1996-05-24 | Allogeneic cell therapy for cancer following allogeneic stem cell transplantation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69633668D1 true DE69633668D1 (de) | 2004-11-25 |
DE69633668T2 DE69633668T2 (de) | 2006-03-09 |
Family
ID=23785397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69633668T Expired - Lifetime DE69633668T2 (de) | 1995-05-25 | 1996-05-24 | Allogene zelltherapie für krebs infolge allogener stammzellen transplantation |
Country Status (8)
Country | Link |
---|---|
US (1) | US6143292A (de) |
EP (1) | EP0831860B1 (de) |
JP (1) | JPH11511746A (de) |
AU (1) | AU5930396A (de) |
CA (1) | CA2220971A1 (de) |
DE (1) | DE69633668T2 (de) |
IL (1) | IL118418A (de) |
WO (1) | WO1996037208A1 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6447767B1 (en) | 1997-05-23 | 2002-09-10 | Hadasit Medical Research Services And Development Ltd. | Non-myeloablative tolerogenic treatment |
US6428782B1 (en) | 1997-05-23 | 2002-08-06 | Hadasit Medical Research Services And Development Ltd. | Non-myeloablative tolerogenic treatment |
AU7798198A (en) * | 1997-05-23 | 1998-12-11 | Baxter International Inc. | Non-myeloablative tolerogenic treatment |
JP4389039B2 (ja) * | 1998-04-09 | 2009-12-24 | 株式会社リンフォテック | アロジェニックな活性化cd4陽性細胞を主成分とする医薬組成物、およびその製造方法、ならびに該医薬組成物調製用キット |
WO1999058977A1 (en) | 1998-05-11 | 1999-11-18 | Miltenyi Biotec Gmbh | Method of direct selection of antigen-specific t cells |
CA2244554A1 (en) * | 1998-07-30 | 2000-01-30 | Vasogen Inc. | Inhibition of graft versus host disease |
US6544506B2 (en) * | 2000-01-05 | 2003-04-08 | Yeda Research & Development Co. Ltd. | Veto cells effective in preventing graft rejection and devoid of graft versus host potential |
EP1427813A2 (de) * | 2000-10-24 | 2004-06-16 | Immunex Corporation | Methode zur auf dendritische zellen beruhenden immunotherapie von tumoren unter verwendung einer kombinationstherapie |
IL155941A0 (en) * | 2000-11-30 | 2003-12-23 | Yeda Res & Dev | Methods of utilizing cultured non-gvhd inducing t lymphocytes to treat disease |
DE10112851C1 (de) | 2001-03-16 | 2002-10-10 | Gsf Forschungszentrum Umwelt | Semi-allogene Antitumor-Vakzine mit HLA-haplo-identischen Antigen-präsentierenden Zellen |
EP1450828B1 (de) | 2001-08-17 | 2015-04-01 | Roger Williams Hospital | In situ-immunisierung |
US20050064587A1 (en) * | 2001-09-07 | 2005-03-24 | Lawrence Rosenberg | Pancreatic small cells and uses thereof |
JP4562353B2 (ja) * | 2002-04-08 | 2010-10-13 | 株式会社リンフォテック | Hla一致他人由来活性化リンパ球を含有してなる腫瘍・感染症および自己免疫疾患の予防・治療用製剤 |
US20050084967A1 (en) | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
AU2004227204B2 (en) | 2003-04-08 | 2010-06-03 | Yeda Research And Development Co. Ltd | Stem cells having increased sensitivity to SDF-1 and methods of generating and using same |
FR2853551B1 (fr) | 2003-04-09 | 2006-08-04 | Lab Francais Du Fractionnement | Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee |
US7435592B2 (en) * | 2003-05-13 | 2008-10-14 | Immunovative Therapies, Ltd. | Compositions for allogeneic cell therapy |
WO2005021734A2 (en) * | 2003-09-02 | 2005-03-10 | University Of Massachussets | Generation of hematopoietic chimerism and induction of central tolerance |
IL158868A0 (en) | 2003-11-13 | 2004-05-12 | Yeda Res & Dev | Methods of generating and using stem cells enriched with immature primitive progenitor |
WO2006004592A2 (en) * | 2004-05-28 | 2006-01-12 | Mayo Foundation For Medical Education And Research | Methods for autologous stem cell transplantation |
WO2006012416A2 (en) | 2004-07-20 | 2006-02-02 | Isogenis, Inc. | Specific inhibition of autoimmunity and diseases associated with autoantigens |
PL2068930T3 (pl) | 2006-08-07 | 2013-02-28 | Abbvie Biotherapeutics Inc | Kompozycje i sposoby wykorzystujące przeciwciało anty-CS1 do leczenia szpiczaka mnogiego |
LT2641601T (lt) | 2006-08-07 | 2016-10-10 | Abbvie Biotherapeutics Inc. | Daugybinės mielomos, naudojant kombinuotas terapijas, pagrįstas huluc63 su bortezomibu, gydymo būdai |
EP2069478A2 (de) * | 2006-08-07 | 2009-06-17 | PDL BioPharma, Inc. | Verwendung von allogenetischen effektorzellen und anti-cs1-antikörpern zur selektiven tötung von mehrfach-myelom-zellen |
WO2010058023A1 (en) | 2008-11-24 | 2010-05-27 | Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt Gmbh | High affinity t cell receptor and use thereof |
CA2799516C (en) * | 2010-08-06 | 2016-01-05 | Canine-Lab.Inc. | Immunological function enhancing agent |
CN104906139B (zh) * | 2011-01-10 | 2020-10-23 | 小利兰·斯坦福大学托管委员会 | 异源造血干细胞移植的增强 |
WO2013167136A1 (en) | 2012-05-08 | 2013-11-14 | Herlev Hospital | Improving adoptive cell therapy with interferon gamma |
US9868939B2 (en) | 2013-06-12 | 2018-01-16 | Wisconsin Alumni Research Foundation | Generating vasculogenic cell populations |
US10365280B2 (en) | 2014-10-02 | 2019-07-30 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating malignancies |
WO2016073184A1 (en) | 2014-11-04 | 2016-05-12 | Dana Farber Cancer Institute, Inc. | Compositions and methods for treating multiple myeloma |
JP6691921B2 (ja) | 2015-02-20 | 2020-05-13 | ウィスコンシン アラムニ リサーチ ファンデーション | 動脈内皮細胞集団の生成 |
JP7185530B2 (ja) | 2016-06-13 | 2022-12-07 | トルク セラピューティクス, インコーポレイテッド | 免疫細胞機能を促進するための方法および組成物 |
CN111432836A (zh) | 2017-09-05 | 2020-07-17 | 转矩医疗股份有限公司 | 治疗性蛋白质组合物及其制备和使用方法 |
WO2020051453A1 (en) | 2018-09-07 | 2020-03-12 | Wisconsin Alumni Research Foundation | Generation of hematopoietic progenitor cells from human pluripotent stem cells |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991012849A1 (en) * | 1990-02-27 | 1991-09-05 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Engrafting allogeneic tissues or organs using interleukin |
IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
-
1996
- 1996-05-24 WO PCT/US1996/007652 patent/WO1996037208A1/en active IP Right Grant
- 1996-05-24 AU AU59303/96A patent/AU5930396A/en not_active Abandoned
- 1996-05-24 JP JP8535902A patent/JPH11511746A/ja not_active Ceased
- 1996-05-24 CA CA002220971A patent/CA2220971A1/en not_active Abandoned
- 1996-05-24 US US08/930,071 patent/US6143292A/en not_active Expired - Fee Related
- 1996-05-24 DE DE69633668T patent/DE69633668T2/de not_active Expired - Lifetime
- 1996-05-24 EP EP96916613A patent/EP0831860B1/de not_active Expired - Lifetime
- 1996-05-26 IL IL118418A patent/IL118418A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL118418A0 (en) | 1996-09-12 |
JPH11511746A (ja) | 1999-10-12 |
IL118418A (en) | 2006-12-31 |
CA2220971A1 (en) | 1996-11-28 |
US6143292A (en) | 2000-11-07 |
MX9708989A (es) | 1998-03-31 |
EP0831860B1 (de) | 2004-10-20 |
DE69633668T2 (de) | 2006-03-09 |
EP0831860A1 (de) | 1998-04-01 |
AU5930396A (en) | 1996-12-11 |
WO1996037208A1 (en) | 1996-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |