DE69636289D1 - Vernetzten polymerisatmassen und verfahren für ihre verwendung - Google Patents

Vernetzten polymerisatmassen und verfahren für ihre verwendung

Info

Publication number
DE69636289D1
DE69636289D1 DE69636289T DE69636289T DE69636289D1 DE 69636289 D1 DE69636289 D1 DE 69636289D1 DE 69636289 T DE69636289 T DE 69636289T DE 69636289 T DE69636289 T DE 69636289T DE 69636289 D1 DE69636289 D1 DE 69636289D1
Authority
DE
Germany
Prior art keywords
groups
synthetic polymer
polymerisate
networked
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69636289T
Other languages
English (en)
Other versions
DE69636289T2 (de
Inventor
M Rhee
A Delustro
A Berg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angiodevice International GmbH
Original Assignee
Angiotech Biomaterials Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24293438&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69636289(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Angiotech Biomaterials Corp filed Critical Angiotech Biomaterials Corp
Application granted granted Critical
Publication of DE69636289D1 publication Critical patent/DE69636289D1/de
Publication of DE69636289T2 publication Critical patent/DE69636289T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043Mixtures of macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/041Mixtures of macromolecular compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08HDERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00Macromolecular products derived from proteins
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08HDERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00Macromolecular products derived from proteins
    • C08H1/06Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23Carbohydrates
    • A61L2300/232Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/90Stent for heart valve
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901Method of manufacturing prosthetic device
DE69636289T 1995-12-18 1996-12-18 Vernetzten polymerisatmassen und verfahren für ihre verwendung Expired - Lifetime DE69636289T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57379995A 1995-12-18 1995-12-18
US573799 1995-12-18
PCT/US1996/019975 WO1997022371A1 (en) 1995-12-18 1996-12-18 Crosslinked polymer compositions and methods for their use

Publications (2)

Publication Number Publication Date
DE69636289D1 true DE69636289D1 (de) 2006-08-03
DE69636289T2 DE69636289T2 (de) 2007-05-10

Family

ID=24293438

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69636289T Expired - Lifetime DE69636289T2 (de) 1995-12-18 1996-12-18 Vernetzten polymerisatmassen und verfahren für ihre verwendung

Country Status (11)

Country Link
US (14) US5874500A (de)
EP (3) EP2111876B1 (de)
JP (4) JP4193917B2 (de)
AT (2) ATE523211T1 (de)
AU (1) AU717660B2 (de)
CA (1) CA2239775C (de)
DE (1) DE69636289T2 (de)
DK (3) DK2111876T3 (de)
ES (3) ES2420106T3 (de)
PT (3) PT1704878E (de)
WO (1) WO1997022371A1 (de)

Families Citing this family (1003)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100361933B1 (ko) * 1993-09-08 2003-02-14 라 졸라 파마슈티칼 컴파니 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
US6551574B2 (en) * 1995-06-07 2003-04-22 Rhomed Incorporated Tuftsin metallopeptide analogs and uses thereof
US6458889B1 (en) * 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US6833408B2 (en) * 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
JP4193917B2 (ja) * 1995-12-18 2008-12-10 アンジオデバイス インターナショナル ゲーエムベーハー 架橋ポリマー組成物およびその使用方法
US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
US6126682A (en) 1996-08-13 2000-10-03 Oratec Interventions, Inc. Method for treating annular fissures in intervertebral discs
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) * 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US20020064546A1 (en) * 1996-09-13 2002-05-30 J. Milton Harris Degradable poly(ethylene glycol) hydrogels with controlled half-life and precursors therefor
WO1998012274A1 (en) 1996-09-23 1998-03-26 Chandrashekar Pathak Methods and devices for preparing protein concentrates
US8003705B2 (en) * 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
US20090324721A1 (en) * 1996-09-23 2009-12-31 Jack Kennedy Hydrogels Suitable For Use In Polyp Removal
US7009034B2 (en) * 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US6258351B1 (en) 1996-11-06 2001-07-10 Shearwater Corporation Delivery of poly(ethylene glycol)-modified molecules from degradable hydrogels
EP0873145A2 (de) 1996-11-15 1998-10-28 Advanced Bio Surfaces, Inc. Biomaterialsystem für in-situ gewebewiederherstellung
US6743248B2 (en) 1996-12-18 2004-06-01 Neomend, Inc. Pretreatment method for enhancing tissue adhesion
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US20040176801A1 (en) * 1997-03-12 2004-09-09 Neomend, Inc. Pretreatment method for enhancing tissue adhesion
US6371975B2 (en) 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
US20030191496A1 (en) 1997-03-12 2003-10-09 Neomend, Inc. Vascular sealing device with microwave antenna
US8172897B2 (en) 1997-04-15 2012-05-08 Advanced Cardiovascular Systems, Inc. Polymer and metal composite implantable medical devices
US6240616B1 (en) 1997-04-15 2001-06-05 Advanced Cardiovascular Systems, Inc. Method of manufacturing a medicated porous metal prosthesis
US10028851B2 (en) 1997-04-15 2018-07-24 Advanced Cardiovascular Systems, Inc. Coatings for controlling erosion of a substrate of an implantable medical device
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
EP1011690A4 (de) * 1997-07-03 2006-08-23 Depuy Spine Inc Vernetzte poysaccharide als arzneistoffträger
GB2328443B (en) 1997-08-21 2001-09-05 Reckitt & Colmann Prod Ltd In situ formation of pharmaceutically acceptable polymeric material
US6229009B1 (en) * 1997-08-29 2001-05-08 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Polycarboxylic based cross-linked copolymers
EP1056413A4 (de) * 1998-02-27 2003-08-20 Bioelastics Res Ltd Injizierbare implantate zur vergrösserung und wiederherstellung von gewebe
MXPA00011312A (es) * 1998-05-20 2003-04-22 Expression Genetics Inc Un vehiculo de gen polimerico de poli-l.lisina injertada con polietilenglicol con porcion de enfoque hepatocitos.
MXPA00000009A (es) 1998-06-22 2005-09-08 Autologous Wound Therapy Inc Solicitud para patente de utilidad para curativo de heridas mejorado enriquecido con plaquetas.
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
US6152943A (en) 1998-08-14 2000-11-28 Incept Llc Methods and apparatus for intraluminal deposition of hydrogels
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
US7790192B2 (en) 1998-08-14 2010-09-07 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US7347850B2 (en) 1998-08-14 2008-03-25 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
US6703047B2 (en) * 2001-02-02 2004-03-09 Incept Llc Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use
US6605294B2 (en) * 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
JP4860817B2 (ja) * 1998-08-26 2012-01-25 ネオメンド、インク. 化学的に架橋した機械的障壁または被覆構造体をインサイチュ作成するための組成物、システムおよび方法
US6458147B1 (en) 1998-11-06 2002-10-01 Neomend, Inc. Compositions, systems, and methods for arresting or controlling bleeding or fluid leakage in body tissue
US6994686B2 (en) 1998-08-26 2006-02-07 Neomend, Inc. Systems for applying cross-linked mechanical barriers
WO2000015117A1 (en) 1998-09-17 2000-03-23 Focal, Inc. Self-cleaning fluid delivery device for medical applications
US7662409B2 (en) 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US7087577B2 (en) * 1998-10-16 2006-08-08 Zimmer Orthobiologies, Inc. Method of promoting natural bypass
US6992066B2 (en) * 1998-10-16 2006-01-31 Zimmer Orthobiologics, Inc. Povidone-containing carriers for polypeptide growth factors
US7351249B2 (en) * 1998-11-06 2008-04-01 Neomend, Inc. Systems, methods, and compositions for achieving closure of suture sites
US6830756B2 (en) 1998-11-06 2004-12-14 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US6949114B2 (en) 1998-11-06 2005-09-27 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US7279001B2 (en) * 1998-11-06 2007-10-09 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US6899889B1 (en) * 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
GB9824562D0 (en) * 1998-11-09 1999-01-06 Cole Polytechnique Fudurale De Materials and methods relating to surface functioning polymers for tissue engineering
US20080114092A1 (en) * 1998-12-04 2008-05-15 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
WO2000033764A1 (en) 1998-12-04 2000-06-15 Pathak Chandrashekhar P Biocompatible crosslinked polymers
US6458953B1 (en) * 1998-12-09 2002-10-01 La Jolla Pharmaceutical Company Valency platform molecules comprising carbamate linkages
US7449019B2 (en) * 1999-01-25 2008-11-11 Smith & Nephew, Inc. Intervertebral decompression
CA2359318C (en) 1999-02-01 2009-06-30 Donald Elbert Biomaterials formed by nucleophilic addition reaction to conjugated unsaturated groups
US6958212B1 (en) 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
US6416776B1 (en) * 1999-02-18 2002-07-09 St. Francis Medical Technologies, Inc. Biological disk replacement, bone morphogenic protein (BMP) carriers, and anti-adhesion materials
US6656496B1 (en) * 1999-03-01 2003-12-02 The Uab Research Foundation Porous tissue scaffolding materials and uses thereof
US6340465B1 (en) 1999-04-12 2002-01-22 Edwards Lifesciences Corp. Lubricious coatings for medical devices
WO2000063268A1 (en) 1999-04-16 2000-10-26 Wm. Marsh Rice University Poly(propylene fumarate) cross linked with poly(ethylene glycol)
US6312725B1 (en) 1999-04-16 2001-11-06 Cohesion Technologies, Inc. Rapid gelling biocompatible polymer composition
WO2000075105A1 (en) * 1999-06-08 2000-12-14 La Jolla Pharmaceutical Company Valency platform molecules comprising aminooxy groups
KR100698559B1 (ko) 1999-06-11 2007-03-21 넥타르 테라퓨틱스 에이엘, 코포레이션 키토산 및 폴리(에틸렌 글리콜) 또는 관련 폴리머로부터유래되는 하이드로겔
ATE341345T1 (de) 1999-06-11 2006-10-15 Cytyc Corp Flüssige gelformulierung zum detektieren von milchkanälen in der brust vor einer chirurgischen ablation des brustgewebes
WO2000078285A1 (en) * 1999-06-18 2000-12-28 University Of Medicine And Dentistry Of New Jersey Controlled release of therapeutics by in-situ entrapment by matrix cross-linking
US6521431B1 (en) * 1999-06-22 2003-02-18 Access Pharmaceuticals, Inc. Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments
US6309660B1 (en) 1999-07-28 2001-10-30 Edwards Lifesciences Corp. Universal biocompatible coating platform for medical devices
JP2003508564A (ja) 1999-08-27 2003-03-04 コヒージョン テクノロジーズ, インコーポレイテッド 高強度の医療用シーラントとして使用するための相互侵入ポリマー網目構造を形成する組成物
US7807211B2 (en) 1999-09-03 2010-10-05 Advanced Cardiovascular Systems, Inc. Thermal treatment of an implantable medical device
US7682647B2 (en) * 1999-09-03 2010-03-23 Advanced Cardiovascular Systems, Inc. Thermal treatment of a drug eluting implantable medical device
US20040029952A1 (en) * 1999-09-03 2004-02-12 Yung-Ming Chen Ethylene vinyl alcohol composition and coating
US6759054B2 (en) 1999-09-03 2004-07-06 Advanced Cardiovascular Systems, Inc. Ethylene vinyl alcohol composition and coating
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US20070032853A1 (en) * 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
CN2389638Y (zh) * 1999-09-07 2000-08-02 曹孟君 聚丙烯酰胺水凝胶乳房假体
US7008635B1 (en) 1999-09-10 2006-03-07 Genzyme Corporation Hydrogels for orthopedic repair
US6371984B1 (en) * 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6783546B2 (en) * 1999-09-13 2004-08-31 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US20080299213A2 (en) * 1999-11-05 2008-12-04 Donald Kleinsek Augmentation and repair of spincter defects with cells including adipocytic cells
US20090074729A2 (en) * 1999-11-05 2009-03-19 Donald Kleinsek Augmentation and repair of spincter defects with cells including fibroblasts
US20080286242A2 (en) * 1999-11-05 2008-11-20 Donald Kleinsek Augmentation and repair of spincter defects with cells including mesenchymal cells
ES2491866T3 (es) * 1999-11-15 2014-09-08 Piramal Healthcare (Canada) Limited Disolución biopolimérica acuosa autogelificante controlada por la temperatura y dependiente del pH
DK1244388T3 (da) 1999-12-06 2007-05-14 Warsaw Orthopedic Inc Indretning til behandling af mellemhvirvelskiver
US20050238686A1 (en) * 1999-12-23 2005-10-27 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6908624B2 (en) * 1999-12-23 2005-06-21 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
AU778318B2 (en) * 2000-02-03 2004-11-25 Tissuemed Limited Device for the closure of a surgical puncture
AU2001257577A1 (en) 2000-02-28 2001-09-03 Shearwater Corporation Water-soluble polymer conjugates of artelinic acid
DE60130544T2 (de) 2000-03-13 2008-06-26 Biocure, Inc. Embolische zusammensetzungen
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
ATE310752T1 (de) * 2000-03-13 2005-12-15 Biocure Inc Biomedizinische artikel aus hydrogel
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
CA2400319C (en) * 2000-03-15 2008-09-16 Orbus Medical Technologies Inc. Coating that promotes endothelial cell adherence
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8460367B2 (en) 2000-03-15 2013-06-11 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US6730763B1 (en) * 2000-03-29 2004-05-04 Toagosei Co., Ltd. Composition
US6723335B1 (en) * 2000-04-07 2004-04-20 Jeffrey William Moehlenbruck Methods and compositions for treating intervertebral disc degeneration
US6527801B1 (en) * 2000-04-13 2003-03-04 Advanced Cardiovascular Systems, Inc. Biodegradable drug delivery material for stent
US7875283B2 (en) * 2000-04-13 2011-01-25 Advanced Cardiovascular Systems, Inc. Biodegradable polymers for use with implantable medical devices
US8109994B2 (en) 2003-01-10 2012-02-07 Abbott Cardiovascular Systems, Inc. Biodegradable drug delivery material for stent
US6884778B2 (en) * 2000-04-14 2005-04-26 William Marsh Rice University Biocompatible macromers
JP5090604B2 (ja) 2000-04-25 2012-12-05 オシリス セラピューティクス,インコーポレイテッド 動物の関節修復のための医薬組成物調製への間葉幹細胞の使用法
US6800298B1 (en) 2000-05-11 2004-10-05 Clemson University Biological lubricant composition and method of applying lubricant composition
US7682648B1 (en) 2000-05-31 2010-03-23 Advanced Cardiovascular Systems, Inc. Methods for forming polymeric coatings on stents
US7291673B2 (en) 2000-06-02 2007-11-06 Eidgenossiche Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
AU2001268228A1 (en) 2000-06-08 2001-12-17 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
US20020076443A1 (en) * 2000-06-19 2002-06-20 Stanley Stein Multiple phase cross-linked compositions and uses thereof
DK1295611T3 (da) * 2000-06-20 2010-10-04 Dainippon Sumitomo Pharma Co Oligonukleotid-transformerende forbindelser
DK1294414T3 (da) * 2000-06-29 2006-07-24 Biosyntech Canada Inc Præparat og fremgangsmåde til heling og regenerering af brusk og andre væv
KR20030032977A (ko) * 2000-07-12 2003-04-26 그리폰 테라퓨틱스, 인코포레이티드 키모카인 수용체 조절제, 제조 및 사용
US6451373B1 (en) 2000-08-04 2002-09-17 Advanced Cardiovascular Systems, Inc. Method of forming a therapeutic coating onto a surface of an implantable prosthesis
US7118737B2 (en) 2000-09-08 2006-10-10 Amylin Pharmaceuticals, Inc. Polymer-modified synthetic proteins
RU2003109746A (ru) * 2000-09-08 2005-01-27 Грифон Терапьютикс, Инк. (Us) Синтетические белки, стимулирующие эритропоэз
EP1324802B1 (de) * 2000-09-12 2006-11-15 Peter K. Law Katheter für den myogenen zelltransfer
US20050165428A1 (en) * 2000-09-25 2005-07-28 Franco Kenneth L. Absorable surgical structure
WO2002024114A2 (en) * 2000-09-25 2002-03-28 Cohesion Technologies, Inc. Resorbable anastomosis stents and plugs
US6953560B1 (en) 2000-09-28 2005-10-11 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
JP4070605B2 (ja) * 2000-10-19 2008-04-02 アイトゲノッシスシェ・テヒニッシュ・ホーホシューレ・ツューリヒ 多官能性自己集成系のためのブロックコポリマー
DE60108258T2 (de) * 2000-10-23 2006-03-16 Tissuemed Ltd. Selbstklebende, hydratierbare matrix für therapeutische anwendungen
AU1538702A (en) * 2000-10-24 2002-05-06 Cryolife Inc In situ bioprosthetic filler and methods, particularly for the in situ formationof vertebral disc bioprosthetics
US7807210B1 (en) 2000-10-31 2010-10-05 Advanced Cardiovascular Systems, Inc. Hemocompatible polymers on hydrophobic porous polymers
US20090130066A1 (en) * 2000-11-06 2009-05-21 Gerigene Medical Corporation Augmentation and repair of sphincter defects with cells including muscle cells
EP1416946B1 (de) * 2000-11-07 2017-12-20 CryoLife, Inc. Expandierbare schaumähnliche biomaterialien und verfahren
US20040091540A1 (en) * 2000-11-15 2004-05-13 Desrosiers Eric Andre Method for restoring a damaged or degenerated intervertebral disc
US6824559B2 (en) * 2000-12-22 2004-11-30 Advanced Cardiovascular Systems, Inc. Ethylene-carboxyl copolymers as drug delivery matrices
US7504125B1 (en) 2001-04-27 2009-03-17 Advanced Cardiovascular Systems, Inc. System and method for coating implantable devices
US6663662B2 (en) * 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
TWI246524B (en) 2001-01-19 2006-01-01 Shearwater Corp Multi-arm block copolymers as drug delivery vehicles
US7265186B2 (en) * 2001-01-19 2007-09-04 Nektar Therapeutics Al, Corporation Multi-arm block copolymers as drug delivery vehicles
US8038708B2 (en) 2001-02-05 2011-10-18 Cook Medical Technologies Llc Implantable device with remodelable material and covering material
WO2002067908A1 (en) * 2001-02-26 2002-09-06 Duke University Novel dendritic polymers and their biomedical uses
US20020177223A1 (en) * 2001-03-12 2002-11-28 Ogle Mathew F. Methods and compositions for crosslinking tissue
MXPA03008498A (es) * 2001-03-20 2005-06-30 Univ Zuerich Procesamiento en dos fases de polimeros termosensibles para uso como biomateriales.
US6780424B2 (en) * 2001-03-30 2004-08-24 Charles David Claude Controlled morphologies in polymer drug for release of drugs from polymer films
US7615593B2 (en) 2001-04-23 2009-11-10 Wisconsin Alumni Research Foundation Bifunctional-modified hydrogels
US20050276858A1 (en) * 2001-04-23 2005-12-15 Kao Weiyuan J Bifunctional-modified hydrogels
US6712845B2 (en) * 2001-04-24 2004-03-30 Advanced Cardiovascular Systems, Inc. Coating for a stent and a method of forming the same
WO2002089676A2 (en) * 2001-05-04 2002-11-14 Concentric Medical Hydrogel filament vaso-occlusive device
EP1392182A1 (de) * 2001-05-04 2004-03-03 Concentric Medical Hydrogel-vorrichtung zum verschluss eines blutgefässes
AU2002340749A1 (en) * 2001-05-04 2002-11-18 Concentric Medical Coated combination vaso-occlusive device
US6656506B1 (en) * 2001-05-09 2003-12-02 Advanced Cardiovascular Systems, Inc. Microparticle coated medical device
US20030166197A1 (en) * 2001-05-10 2003-09-04 Ecker Joseph R. Ethylene insensitive plants
US6743462B1 (en) 2001-05-31 2004-06-01 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating implantable devices
US20070078435A1 (en) * 2001-06-14 2007-04-05 Corbett Stone Tissue augmentation methods using a medical injection apparatus
US6702744B2 (en) * 2001-06-20 2004-03-09 Advanced Cardiovascular Systems, Inc. Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery
ES2324525T3 (es) * 2001-06-20 2009-08-10 Dainippon Sumitomo Pharma Co., Ltd. Metodo para promover transferencia de acidos nucleicos.
US8741378B1 (en) 2001-06-27 2014-06-03 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device
US6695920B1 (en) 2001-06-27 2004-02-24 Advanced Cardiovascular Systems, Inc. Mandrel for supporting a stent and a method of using the mandrel to coat a stent
US7247313B2 (en) * 2001-06-27 2007-07-24 Advanced Cardiovascular Systems, Inc. Polyacrylates coatings for implantable medical devices
US7175873B1 (en) 2001-06-27 2007-02-13 Advanced Cardiovascular Systems, Inc. Rate limiting barriers for implantable devices and methods for fabrication thereof
US20040077835A1 (en) * 2001-07-12 2004-04-22 Robin Offord Chemokine receptor modulators, production and use
US7246321B2 (en) * 2001-07-13 2007-07-17 Anoto Ab Editing data
US7682669B1 (en) 2001-07-30 2010-03-23 Advanced Cardiovascular Systems, Inc. Methods for covalently immobilizing anti-thrombogenic material into a coating on a medical device
US6663596B2 (en) * 2001-08-13 2003-12-16 Scimed Life Systems, Inc. Delivering material to a patient
US7022135B2 (en) * 2001-08-17 2006-04-04 Medtronic, Inc. Film with highly porous vascular graft prostheses
JP4230135B2 (ja) * 2001-08-21 2009-02-25 独立行政法人科学技術振興機構 多官能性架橋剤によって架橋したグリコサミノグリカン−コラーゲン複合体の製造法
JP4302518B2 (ja) 2001-08-31 2009-07-29 ケラテク リミテッド 可溶性s−スルホン化ケラチン誘導体からの生体高分子材料の薄膜、繊維、発泡体又は接着剤の製造
US8303651B1 (en) * 2001-09-07 2012-11-06 Advanced Cardiovascular Systems, Inc. Polymeric coating for reducing the rate of release of a therapeutic substance from a stent
US7989018B2 (en) 2001-09-17 2011-08-02 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US7285304B1 (en) 2003-06-25 2007-10-23 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US6863683B2 (en) 2001-09-19 2005-03-08 Abbott Laboratoris Vascular Entities Limited Cold-molding process for loading a stent onto a stent delivery system
US6753071B1 (en) 2001-09-27 2004-06-22 Advanced Cardiovascular Systems, Inc. Rate-reducing membrane for release of an agent
US7223282B1 (en) 2001-09-27 2007-05-29 Advanced Cardiovascular Systems, Inc. Remote activation of an implantable device
DK1435877T3 (da) 2001-10-15 2009-08-03 Hemoteq Ag Overtrækning af stents for at forhindre restenose
WO2003034925A2 (en) 2001-10-23 2003-05-01 Tyco Healthcare Group Lp Surgical fasteners
DE10152407A1 (de) * 2001-10-24 2003-05-08 Aesculap Ag & Co Kg Zusammensetzung aus mindestens zwei biokompatiblen chemisch vernetzbaren Komponenten
US20030093111A1 (en) * 2001-10-26 2003-05-15 Concentric Medical Device for vaso-occlusion and interventional therapy
US7799833B2 (en) * 2001-11-01 2010-09-21 Spine Wave, Inc. System and method for the pretreatment of the endplates of an intervertebral disc
AU2002336694A1 (en) 2001-11-01 2003-05-12 Lawrence M. Boyd Devices and methods for the restoration of a spinal disc
US20070264227A1 (en) * 2001-11-07 2007-11-15 Eidgenossische Technische Hochschule Zurich Synthetic Matrix for Controlled Cell Ingrowth and Tissue Regeneration
US7026440B2 (en) 2001-11-07 2006-04-11 Nektar Therapeutics Al, Corporation Branched polymers and their conjugates
KR101054023B1 (ko) * 2001-11-07 2011-08-04 아이드게노시셰 테크시셰 호흐쉘 취리히 세포 내증식 및 조직 재생을 제어하기 위한 합성 매트릭스
US7585516B2 (en) 2001-11-12 2009-09-08 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices
US7629388B2 (en) * 2001-11-20 2009-12-08 William Marsh Rice University Synthesis and characterization of biodegradable cationic poly(propylene fumarate-co-ethylene glycol) copolymer hydrogels modified with agmatine for enhanced cell adhesion
US8608661B1 (en) 2001-11-30 2013-12-17 Advanced Cardiovascular Systems, Inc. Method for intravascular delivery of a treatment agent beyond a blood vessel wall
US20040010251A1 (en) * 2001-12-10 2004-01-15 Shahar Pitaru Methods, devices, and preparations for intervertebral disc treatment
US7232802B2 (en) * 2001-12-21 2007-06-19 Zimmer Orthobiologics, Inc. Compositions and methods for promoting myocardial and peripheral angiogenesis
US20030181371A1 (en) * 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
US6709514B1 (en) * 2001-12-28 2004-03-23 Advanced Cardiovascular Systems, Inc. Rotary coating apparatus for coating implantable medical devices
WO2003063926A1 (de) * 2002-02-01 2003-08-07 Sustech Gmbh & Co. Kg Sternförmige präpolymere für die herstellung ultradünner, hydrogel-bildender beschichtungen
US20030229333A1 (en) * 2002-02-22 2003-12-11 Control Delivery Systems, Inc. Methods for treating otic disorders
US20040131582A1 (en) * 2002-02-26 2004-07-08 Grinstaff Mark W. Novel dendritic polymers and their biomedical uses
US7630403B2 (en) * 2002-03-08 2009-12-08 Texas Instruments Incorporated MAC aggregation frame with MSDU and fragment of MSDU
US6812211B2 (en) * 2002-03-19 2004-11-02 Michael Andrew Slivka Method for nonsurgical treatment of the intervertebral disc and kit therefor
US20030179692A1 (en) * 2002-03-19 2003-09-25 Yoshitaka Ohotomo Storage medium
US7022334B1 (en) 2002-03-20 2006-04-04 Advanced Cardiovascular Systems, Inc. Therapeutic composition and a method of coating implantable medical devices
US7919075B1 (en) 2002-03-20 2011-04-05 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices
US8282912B2 (en) 2002-03-22 2012-10-09 Kuros Biosurgery, AG Compositions for tissue augmentation
EP1494730B1 (de) * 2002-03-22 2012-01-18 Kuros Biosurgery AG Zusammensetzung für die verstärkung von hartem gewebe
US6953465B2 (en) 2002-03-25 2005-10-11 Concentric Medical, Inc. Containers and methods for delivering vaso-occluding filaments and particles
EP1364663A1 (de) * 2002-05-21 2003-11-26 Commonwealth Scientific And Industrial Research Organisation Okulare Vorrichtungen mit funktionalisierter Oberfläche mit adhäsiven Eigenschaften
CA2488721A1 (en) * 2002-06-10 2003-12-18 Keratec Limited Orthopaedic materials derived from keratin
US7037983B2 (en) 2002-06-14 2006-05-02 Kimberly-Clark Worldwide, Inc. Methods of making functional biodegradable polymers
US20030232088A1 (en) * 2002-06-14 2003-12-18 Kimberly-Clark Worldwide, Inc. Materials with both bioadhesive and biodegradable components
US7794743B2 (en) * 2002-06-21 2010-09-14 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of making the same
US7217426B1 (en) 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
US20040115271A1 (en) * 2002-06-21 2004-06-17 Alex Sacharoff Hydration compositions for corneal pre-surgery treatment
US7396539B1 (en) * 2002-06-21 2008-07-08 Advanced Cardiovascular Systems, Inc. Stent coatings with engineered drug release rate
US8506617B1 (en) 2002-06-21 2013-08-13 Advanced Cardiovascular Systems, Inc. Micronized peptide coated stent
US7033602B1 (en) 2002-06-21 2006-04-25 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of coating implantable medical devices
US7056523B1 (en) 2002-06-21 2006-06-06 Advanced Cardiovascular Systems, Inc. Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine
EP1536746B1 (de) * 2002-06-24 2013-05-08 Incept, LLC Füllstoffe und verfahren zur verdrängung von gewebe zur verbesserung des radiologischen resultats
US7361368B2 (en) 2002-06-28 2008-04-22 Advanced Cardiovascular Systems, Inc. Device and method for combining a treatment agent and a gel
WO2004002469A1 (de) * 2002-06-29 2004-01-08 Aquanova German Solubilisate Technologies (Agt) Gmbh Isoflavonkonzentrate sowie verfahren zu ihrer herstellung
US20060094643A1 (en) * 2002-07-03 2006-05-04 Yuri Svirkin Compositions of hyaluronic acid and methods of use
US7294329B1 (en) 2002-07-18 2007-11-13 Advanced Cardiovascular Systems, Inc. Poly(vinyl acetal) coatings for implantable medical devices
US7622146B2 (en) * 2002-07-18 2009-11-24 Advanced Cardiovascular Systems, Inc. Rate limiting barriers for implantable devices and methods for fabrication thereof
MXPA05001570A (es) * 2002-08-09 2005-08-19 Ottawa Health Research Inst Matriz biosintetica y sus usos.
US7363074B1 (en) 2002-08-20 2008-04-22 Advanced Cardiovascular Systems, Inc. Coatings comprising self-assembled molecular structures and a method of delivering a drug using the same
US7598224B2 (en) * 2002-08-20 2009-10-06 Biosurface Engineering Technologies, Inc. Dual chain synthetic heparin-binding growth factor analogs
US20040037866A1 (en) * 2002-08-20 2004-02-26 Semertzides John N. Composition and method for the treatment and prevention of adhesions
US7166574B2 (en) 2002-08-20 2007-01-23 Biosurface Engineering Technologies, Inc. Synthetic heparin-binding growth factor analogs
US8227411B2 (en) * 2002-08-20 2012-07-24 BioSurface Engineering Technologies, Incle FGF growth factor analogs
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
US20040054104A1 (en) * 2002-09-05 2004-03-18 Pacetti Stephen D. Coatings for drug delivery devices comprising modified poly(ethylene-co-vinyl alcohol)
US7732535B2 (en) * 2002-09-05 2010-06-08 Advanced Cardiovascular Systems, Inc. Coating for controlled release of drugs from implantable medical devices
AR047712A1 (es) * 2002-09-07 2006-02-15 Royal Veterinary College Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas
JP5156890B2 (ja) 2002-09-11 2013-03-06 独立行政法人物質・材料研究機構 高分子架橋体及びその製造方法
CA2498717A1 (en) 2002-09-13 2004-03-25 Ocular Sciences, Inc. Devices and methods for improving vision
US7201935B1 (en) 2002-09-17 2007-04-10 Advanced Cardiovascular Systems, Inc. Plasma-generated coatings for medical devices and methods for fabricating thereof
US20040054414A1 (en) 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
US20040063805A1 (en) * 2002-09-19 2004-04-01 Pacetti Stephen D. Coatings for implantable medical devices and methods for fabrication thereof
US7217254B2 (en) 2002-09-20 2007-05-15 Genzyme Corporation Multi-pressure biocompatible agent delivery device and method
US7438722B1 (en) 2002-09-20 2008-10-21 Advanced Cardiovascular Systems, Inc. Method for treatment of restenosis
US7232573B1 (en) * 2002-09-26 2007-06-19 Advanced Cardiovascular Systems, Inc. Stent coatings containing self-assembled monolayers
US8202530B2 (en) * 2002-09-27 2012-06-19 Advanced Cardiovascular Systems, Inc. Biocompatible coatings for stents
US7404979B1 (en) 2002-09-30 2008-07-29 Advanced Cardiovascular Systems Inc. Spin coating apparatus and a method for coating implantable devices
US8337937B2 (en) * 2002-09-30 2012-12-25 Abbott Cardiovascular Systems Inc. Stent spin coating method
US7087263B2 (en) * 2002-10-09 2006-08-08 Advanced Cardiovascular Systems, Inc. Rare limiting barriers for implantable medical devices
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
US7497859B2 (en) * 2002-10-29 2009-03-03 Kyphon Sarl Tools for implanting an artificial vertebral disk
US6966929B2 (en) * 2002-10-29 2005-11-22 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with a spacer
KR100794289B1 (ko) * 2002-11-08 2008-01-11 아이진 주식회사 Bmp-7 폴리펩타이드를 포함하는 흉터 형성 억제제
US6896965B1 (en) 2002-11-12 2005-05-24 Advanced Cardiovascular Systems, Inc. Rate limiting barriers for implantable devices
US8034361B2 (en) * 2002-11-12 2011-10-11 Advanced Cardiovascular Systems, Inc. Stent coatings incorporating nanoparticles
US7022372B1 (en) 2002-11-12 2006-04-04 Advanced Cardiovascular Systems, Inc. Compositions for coating implantable medical devices
US6833467B2 (en) * 2002-11-12 2004-12-21 Chung-Shan Institute Of Science & Technology Method for preparing pentaerythritol phosphate alcohol by mechanochemical synthesis
CN100394989C (zh) 2002-11-15 2008-06-18 华沙整形外科股份有限公司 包含微粒状基于胶原材料的组合物的制药应用和包含所述组合物的滑膜关节
US6761651B2 (en) * 2002-11-22 2004-07-13 Chin-Dong Pai Aluminum tennis racket
US6992543B2 (en) * 2002-11-22 2006-01-31 Raytheon Company Mems-tuned high power, high efficiency, wide bandwidth power amplifier
US6982004B1 (en) * 2002-11-26 2006-01-03 Advanced Cardiovascular Systems, Inc. Electrostatic loading of drugs on implantable medical devices
JP2004173941A (ja) * 2002-11-27 2004-06-24 Olympus Corp カルシウム傾斜材料とその製造方法
AU2003283894B2 (en) * 2002-11-28 2009-01-08 Keratec Limited Personal care formulations containing keratin
US7211150B1 (en) 2002-12-09 2007-05-01 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating and drying multiple stents
US7468210B1 (en) 2002-12-10 2008-12-23 Biosurface Engineering Technologies, Inc. Cross-linked heparin coatings and methods
US7776926B1 (en) 2002-12-11 2010-08-17 Advanced Cardiovascular Systems, Inc. Biocompatible coating for implantable medical devices
US7758880B2 (en) * 2002-12-11 2010-07-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications
US7074276B1 (en) 2002-12-12 2006-07-11 Advanced Cardiovascular Systems, Inc. Clamp mandrel fixture and a method of using the same to minimize coating defects
US8435550B2 (en) 2002-12-16 2013-05-07 Abbot Cardiovascular Systems Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US7758881B2 (en) 2004-06-30 2010-07-20 Advanced Cardiovascular Systems, Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US20060002968A1 (en) 2004-06-30 2006-01-05 Gordon Stewart Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders
US20040115164A1 (en) * 2002-12-17 2004-06-17 Pierce Ryan K. Soft filament occlusive device delivery system
US20040192658A1 (en) * 2002-12-27 2004-09-30 Angiotech International Ag Compositions and methods of using collajolie
WO2004061094A1 (en) 2002-12-30 2004-07-22 Gryphon Therapeutics, Inc. Water-soluble thioester and selenoester compounds and methods for making and using the same
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
WO2004060405A2 (en) * 2002-12-30 2004-07-22 Angiotech International Ag Tissue reactive compounds and compositions and uses thereof
JP4585743B2 (ja) * 2003-02-13 2010-11-24 独立行政法人物質・材料研究機構 生体内分解吸収性粘着性医用材料
WO2004081055A1 (ja) * 2003-02-21 2004-09-23 Terumo Kabushiki Kaisha 架橋性多糖誘導体、その製造方法、架橋性多糖組成物および医療用処置材
US8715771B2 (en) * 2003-02-26 2014-05-06 Abbott Cardiovascular Systems Inc. Coated stent and method of making the same
US7255891B1 (en) 2003-02-26 2007-08-14 Advanced Cardiovascular Systems, Inc. Method for coating implantable medical devices
US6926919B1 (en) * 2003-02-26 2005-08-09 Advanced Cardiovascular Systems, Inc. Method for fabricating a coating for a medical device
US7563483B2 (en) * 2003-02-26 2009-07-21 Advanced Cardiovascular Systems Inc. Methods for fabricating a coating for implantable medical devices
US7288609B1 (en) 2003-03-04 2007-10-30 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices based on poly (orthoesters)
KR20060003872A (ko) * 2003-04-04 2006-01-11 티슈메드 리미티드 조직-부착성 제형물
US7273896B2 (en) 2003-04-10 2007-09-25 Angiotech Pharmaceuticals (Us), Inc. Compositions and methods of using a transient colorant
US8383158B2 (en) 2003-04-15 2013-02-26 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
US8821473B2 (en) 2003-04-15 2014-09-02 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
US8038991B1 (en) 2003-04-15 2011-10-18 Abbott Cardiovascular Systems Inc. High-viscosity hyaluronic acid compositions to treat myocardial conditions
US8791171B2 (en) * 2003-05-01 2014-07-29 Abbott Cardiovascular Systems Inc. Biodegradable coatings for implantable medical devices
US7563454B1 (en) * 2003-05-01 2009-07-21 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices
US7279174B2 (en) * 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
EP1624935B1 (de) * 2003-05-15 2016-09-28 The University of Utah Research Foundation Anti-adhäsions-verbundstoffe und anwenungsverfahren dafür
US7323209B1 (en) * 2003-05-15 2008-01-29 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating stents
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7186789B2 (en) * 2003-06-11 2007-03-06 Advanced Cardiovascular Systems, Inc. Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings
US8465537B2 (en) 2003-06-17 2013-06-18 Gel-Del Technologies, Inc. Encapsulated or coated stent systems
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US7645504B1 (en) 2003-06-26 2010-01-12 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophobic and hydrophilic polymers
US7875285B1 (en) 2003-07-15 2011-01-25 Advanced Cardiovascular Systems, Inc. Medicated coatings for implantable medical devices having controlled rate of release
US20050021127A1 (en) * 2003-07-21 2005-01-27 Kawula Paul John Porous glass fused onto stent for drug retention
US7169404B2 (en) * 2003-07-30 2007-01-30 Advanced Cardiovasular Systems, Inc. Biologically absorbable coatings for implantable devices and methods for fabricating the same
US7056591B1 (en) * 2003-07-30 2006-06-06 Advanced Cardiovascular Systems, Inc. Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same
US7645474B1 (en) 2003-07-31 2010-01-12 Advanced Cardiovascular Systems, Inc. Method and system of purifying polymers for use with implantable medical devices
US7431959B1 (en) 2003-07-31 2008-10-07 Advanced Cardiovascular Systems Inc. Method and system for irradiation of a drug eluting implantable medical device
US7785512B1 (en) 2003-07-31 2010-08-31 Advanced Cardiovascular Systems, Inc. Method and system of controlled temperature mixing and molding of polymers with active agents for implantable medical devices
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
JP2007503222A (ja) * 2003-08-20 2007-02-22 ヒストジェニックス コーポレイション 延長された重合時間を有するよう改変した生分解性高分子によって保護された、非細胞軟骨又は骨軟骨病変部位内に埋め込まれる非細胞基質、その調製方法及び使用方法
US7217294B2 (en) * 2003-08-20 2007-05-15 Histogenics Corp. Acellular matrix implants for treatment of articular cartilage, bone or osteochondral defects and injuries and method for use thereof
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
WO2005023181A2 (en) * 2003-08-22 2005-03-17 Vista Scientific Polymeric systems for controlled drug therapy
US7767756B2 (en) * 2003-09-19 2010-08-03 Keraplast Technologies, Ltd. Composite materials containing keratin
US7441513B1 (en) 2003-09-26 2008-10-28 Advanced Cardiovascular Systems, Inc. Plasma-generated coating apparatus for medical devices and a method of coating deposition
US7318932B2 (en) * 2003-09-30 2008-01-15 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same
US7198675B2 (en) 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
US7704544B2 (en) * 2003-10-07 2010-04-27 Advanced Cardiovascular Systems, Inc. System and method for coating a tubular implantable medical device
WO2005039641A2 (en) * 2003-10-15 2005-05-06 The Regents Of The University Of California Biomacromolecule polymer conjugates
US7320707B2 (en) * 2003-11-05 2008-01-22 St. Francis Medical Technologies, Inc. Method of laterally inserting an artificial vertebral disk replacement implant with crossbar spacer
US7329413B1 (en) 2003-11-06 2008-02-12 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
US20050148512A1 (en) * 2003-11-10 2005-07-07 Angiotech International Ag Medical implants and fibrosis-inducing agents
US7943388B2 (en) * 2003-11-14 2011-05-17 3M Innovative Properties Company Acoustic sensors and methods
US7261946B2 (en) 2003-11-14 2007-08-28 Advanced Cardiovascular Systems, Inc. Block copolymers of acrylates and methacrylates with fluoroalkenes
US9066912B2 (en) * 2003-11-17 2015-06-30 Ethicon, Inc. Drug-enhanced adhesion prevention
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
US20050208095A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
US8192752B2 (en) * 2003-11-21 2012-06-05 Advanced Cardiovascular Systems, Inc. Coatings for implantable devices including biologically erodable polyesters and methods for fabricating the same
US7670377B2 (en) 2003-11-21 2010-03-02 Kyphon Sarl Laterally insertable artifical vertebral disk replacement implant with curved spacer
US7560492B1 (en) * 2003-11-25 2009-07-14 Advanced Cardiovascular Systems, Inc. Polysulfone block copolymers as drug-eluting coating material
US7807722B2 (en) * 2003-11-26 2010-10-05 Advanced Cardiovascular Systems, Inc. Biobeneficial coating compositions and methods of making and using thereof
US7503935B2 (en) * 2003-12-02 2009-03-17 Kyphon Sarl Method of laterally inserting an artificial vertebral disk replacement with translating pivot point
CA2549295C (en) * 2003-12-04 2016-05-03 University Of Utah Research Foundation Modified macromolecules and methods of making and using thereof
US20100330143A1 (en) 2003-12-04 2010-12-30 University Of Utah Research Foundation Modified macromolecules and methods of making and using thereof
US20080176205A1 (en) * 2003-12-04 2008-07-24 University Of Utah Research Foundation Process and Formulation to Improve Viability of Stored Cells and Tissue
US8529939B2 (en) 2003-12-08 2013-09-10 Gel-Del Technologies, Inc. Mucoadhesive drug delivery devices and methods of making and using thereof
ES2396689T3 (es) 2003-12-11 2013-02-25 Isto Technologies Inc. Sistema de cartílago particulado
JP4912565B2 (ja) * 2003-12-15 2012-04-11 独立行政法人物質・材料研究機構 生体内分解吸収性粘着性医用材料
US7220816B2 (en) * 2003-12-16 2007-05-22 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same
WO2005058380A1 (en) * 2003-12-19 2005-06-30 Keratec Limited Wound care products containing keratin
EP1696034A4 (de) * 2003-12-19 2006-12-27 Dainippon Sumitomo Pharma Co Neues verfahren zum nukleinsäuretransfer
US7435788B2 (en) * 2003-12-19 2008-10-14 Advanced Cardiovascular Systems, Inc. Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
US8309112B2 (en) * 2003-12-24 2012-11-13 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same
CA2550872C (en) * 2003-12-30 2016-05-03 Stig Bengmark Surface protection of exposed biological tissues
US7342082B2 (en) * 2004-12-17 2008-03-11 3M Innovative Properties Company Soluble polymers as amine capture agents and methods
SE0303588D0 (sv) 2003-12-30 2003-12-30 Bioactive Polymers Ab C O Lund Surface protection of exposed biological tissues
US7402678B2 (en) 2004-12-17 2008-07-22 3M Innovative Properties Company Multifunctional amine capture agents
US20050142161A1 (en) * 2003-12-30 2005-06-30 Freeman Lynetta J. Collagen matrix for soft tissue augmentation
US7803178B2 (en) 2004-01-30 2010-09-28 Trivascular, Inc. Inflatable porous implants and methods for drug delivery
US7414028B1 (en) * 2004-02-04 2008-08-19 Biosurface Engineering Technologies, Inc. Growth factor analogs
US7671012B2 (en) 2004-02-10 2010-03-02 Biosurface Engineering Technologies, Inc. Formulations and methods for delivery of growth factor analogs
US20080227696A1 (en) * 2005-02-22 2008-09-18 Biosurface Engineering Technologies, Inc. Single branch heparin-binding growth factor analogs
US20060024347A1 (en) * 2004-02-10 2006-02-02 Biosurface Engineering Technologies, Inc. Bioactive peptide coatings
US7528105B1 (en) 2004-02-10 2009-05-05 Biosurface Engineering Technologies Heterodimeric chain synthetic heparin-binding growth factor analogs
US8277831B2 (en) * 2004-02-17 2012-10-02 Advanced Technologies And Regenerative Medicine, Llc. Drug-enhanced adhesion prevention
US7709439B2 (en) * 2004-02-20 2010-05-04 Boston Scientific Scimed, Inc. Biomaterials for enhanced healing
WO2005082005A2 (en) 2004-02-20 2005-09-09 Biosurface Engineering Technologies, Inc., Et Al. Positive modulator of bone morphogenic protein-2
US7737214B2 (en) * 2004-03-15 2010-06-15 Terumo Kabushiki Kaisha Adhesion preventive material
US8685431B2 (en) * 2004-03-16 2014-04-01 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on copolymers having ester bonds and methods for fabricating the same
US20060135959A1 (en) * 2004-03-22 2006-06-22 Disc Dynamics, Inc. Nuclectomy method and apparatus
US20050208093A1 (en) * 2004-03-22 2005-09-22 Thierry Glauser Phosphoryl choline coating compositions
US8029511B2 (en) * 2004-03-22 2011-10-04 Disc Dynamics, Inc. Multi-stage biomaterial injection system for spinal implants
US8551512B2 (en) 2004-03-22 2013-10-08 Advanced Cardiovascular Systems, Inc. Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
US20050214339A1 (en) * 2004-03-29 2005-09-29 Yiwen Tang Biologically degradable compositions for medical applications
US8778014B1 (en) 2004-03-31 2014-07-15 Advanced Cardiovascular Systems, Inc. Coatings for preventing balloon damage to polymer coated stents
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8024036B2 (en) 2007-03-19 2011-09-20 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
US9801527B2 (en) 2004-04-19 2017-10-31 Gearbox, Llc Lumen-traveling biological interface device
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US8092549B2 (en) * 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US8000784B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling device
US7998060B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling delivery device
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US7850676B2 (en) 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
BRPI0510477B1 (pt) 2004-04-28 2023-01-17 Angiotech Biomaterials Corporation Método para formar um gel e dispositivo para uso em aplicações médicas
US7820732B2 (en) * 2004-04-30 2010-10-26 Advanced Cardiovascular Systems, Inc. Methods for modulating thermal and mechanical properties of coatings on implantable devices
US8293890B2 (en) * 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
JP4722837B2 (ja) * 2004-05-07 2011-07-13 生化学工業株式会社 髄核充填剤
US20050255045A1 (en) * 2004-05-13 2005-11-17 Woltering Eugene A Surgical marking composition and method
US7758654B2 (en) 2004-05-20 2010-07-20 Kensey Nash Corporation Anti-adhesion device
WO2005115489A2 (en) * 2004-05-24 2005-12-08 Genzyme Corporation Adherent polymeric compositions
US9561309B2 (en) * 2004-05-27 2017-02-07 Advanced Cardiovascular Systems, Inc. Antifouling heparin coatings
ATE385423T1 (de) * 2004-06-16 2008-02-15 Straumann Holding Ag Abdeckmembran
US7282584B2 (en) 2004-06-16 2007-10-16 Straumann Holding Ag Methylene blue
US7563780B1 (en) * 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
AU2005258231A1 (en) * 2004-06-23 2006-01-05 Angiotech Pharmaceuticals (Us), Inc. Methods and crosslinked polymer compositions for cartilage repair
US8568469B1 (en) 2004-06-28 2013-10-29 Advanced Cardiovascular Systems, Inc. Stent locking element and a method of securing a stent on a delivery system
US8241554B1 (en) 2004-06-29 2012-08-14 Advanced Cardiovascular Systems, Inc. Method of forming a stent pattern on a tube
US20050287184A1 (en) * 2004-06-29 2005-12-29 Hossainy Syed F A Drug-delivery stent formulations for restenosis and vulnerable plaque
US20050287218A1 (en) * 2004-06-29 2005-12-29 Hassan Chaouk Biomaterial
AU2005260592B2 (en) 2004-06-29 2011-08-18 Spine Wave, Inc. Methods for treating defects and injuries of an intervertebral disc
DE102004031258A1 (de) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen
EP1761244A4 (de) * 2004-06-30 2009-12-09 Tyco Healthcare Zusammensetzungen auf isocyanatbasis und ihre verwendung
US7654956B2 (en) 2004-07-13 2010-02-02 Dexcom, Inc. Transcutaneous analyte sensor
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US8206448B2 (en) 2004-10-29 2012-06-26 Spinal Restoration, Inc. Injection of fibrin sealant using reconstituted components in spinal applications
US7597687B2 (en) * 2004-10-29 2009-10-06 Spinal Restoration, Inc. Injection of fibrin sealant including an anesthetic in spinal applications
US8357147B2 (en) * 2005-08-17 2013-01-22 Spinal Restoration, Inc. Method for repairing intervertebral discs
US7971333B2 (en) 2006-05-30 2011-07-05 Advanced Cardiovascular Systems, Inc. Manufacturing process for polymetric stents
US8747879B2 (en) * 2006-04-28 2014-06-10 Advanced Cardiovascular Systems, Inc. Method of fabricating an implantable medical device to reduce chance of late inflammatory response
US7731890B2 (en) 2006-06-15 2010-06-08 Advanced Cardiovascular Systems, Inc. Methods of fabricating stents with enhanced fracture toughness
US8747878B2 (en) 2006-04-28 2014-06-10 Advanced Cardiovascular Systems, Inc. Method of fabricating an implantable medical device by controlling crystalline structure
US8778256B1 (en) 2004-09-30 2014-07-15 Advanced Cardiovascular Systems, Inc. Deformation of a polymer tube in the fabrication of a medical article
US7494665B1 (en) * 2004-07-30 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymers containing siloxane monomers
US8357391B2 (en) 2004-07-30 2013-01-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable devices comprising poly (hydroxy-alkanoates) and diacid linkages
KR20070051297A (ko) * 2004-08-03 2007-05-17 티슈메드 리미티드 조직-접착성 물질
US20060040894A1 (en) * 2004-08-13 2006-02-23 Angiotech International Ag Compositions and methods using hyaluronic acid
CA2569736A1 (en) * 2004-08-20 2006-03-02 Russell Anderson Methods of administering microparticles combined with autologous body components
US20060041102A1 (en) * 2004-08-23 2006-02-23 Advanced Cardiovascular Systems, Inc. Implantable devices comprising biologically absorbable polymers having constant rate of degradation and methods for fabricating the same
US9283099B2 (en) 2004-08-25 2016-03-15 Advanced Cardiovascular Systems, Inc. Stent-catheter assembly with a releasable connection for stent retention
US7648727B2 (en) 2004-08-26 2010-01-19 Advanced Cardiovascular Systems, Inc. Methods for manufacturing a coated stent-balloon assembly
US7244443B2 (en) 2004-08-31 2007-07-17 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrophilic monomers
US20060045902A1 (en) * 2004-09-01 2006-03-02 Serbousek Jon C Polymeric wrap for in vivo delivery of osteoinductive formulations
CA2577033A1 (en) * 2004-09-10 2006-03-16 Stichting Dutch Polymer Institute Radiopaque prosthetic intervertebral disc nucleus
US7229471B2 (en) * 2004-09-10 2007-06-12 Advanced Cardiovascular Systems, Inc. Compositions containing fast-leaching plasticizers for improved performance of medical devices
US8303973B2 (en) 2004-09-17 2012-11-06 Angiotech Pharmaceuticals (Us), Inc. Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
US8110211B2 (en) * 2004-09-22 2012-02-07 Advanced Cardiovascular Systems, Inc. Medicated coatings for implantable medical devices including polyacrylates
US20060069438A1 (en) * 2004-09-29 2006-03-30 Zucherman James F Multi-piece artificial spinal disk replacement device with multi-segmented support plates
US8173062B1 (en) 2004-09-30 2012-05-08 Advanced Cardiovascular Systems, Inc. Controlled deformation of a polymer tube in fabricating a medical article
US7875233B2 (en) 2004-09-30 2011-01-25 Advanced Cardiovascular Systems, Inc. Method of fabricating a biaxially oriented implantable medical device
US8043553B1 (en) 2004-09-30 2011-10-25 Advanced Cardiovascular Systems, Inc. Controlled deformation of a polymer tube with a restraining surface in fabricating a medical article
WO2006038866A1 (en) * 2004-10-01 2006-04-13 Bio Polymer Products Of Sweden Ab Improved coating comprising a bioadhesive polyphenolic protein derived from a byssus-forming mussel
US7166680B2 (en) * 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
US8790632B2 (en) 2004-10-07 2014-07-29 Actamax Surgical Materials, Llc Polymer-based tissue-adhesive form medical use
DE602005027862D1 (de) 2004-10-07 2011-06-16 Du Pont Polymer auf basis von polysaccharide für gewebekleber zur medizinischen verwendung
US7235592B2 (en) 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
US7938307B2 (en) 2004-10-18 2011-05-10 Tyco Healthcare Group Lp Support structures and methods of using the same
US7845536B2 (en) 2004-10-18 2010-12-07 Tyco Healthcare Group Lp Annular adhesive structure
US20060089485A1 (en) * 2004-10-27 2006-04-27 Desnoyer Jessica R End-capped poly(ester amide) copolymers
US8603634B2 (en) * 2004-10-27 2013-12-10 Abbott Cardiovascular Systems Inc. End-capped poly(ester amide) copolymers
WO2006050110A2 (en) * 2004-10-28 2006-05-11 Surmodics, Inc. Pro-fibrotic coatings comprising collagen for medical implants
US20060095122A1 (en) * 2004-10-29 2006-05-04 Advanced Cardiovascular Systems, Inc. Implantable devices comprising biologically absorbable star polymers and methods for fabricating the same
US7390497B2 (en) * 2004-10-29 2008-06-24 Advanced Cardiovascular Systems, Inc. Poly(ester amide) filler blends for modulation of coating properties
US20110213464A1 (en) * 2004-10-29 2011-09-01 Whitlock Steven I Injection of fibrin sealant in the absence of corticosteroids in spinal applications
US7201918B2 (en) * 2004-11-16 2007-04-10 Microvention, Inc. Compositions, systems and methods for treatment of defects in blood vessels
US7214759B2 (en) * 2004-11-24 2007-05-08 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
US7588642B1 (en) 2004-11-29 2009-09-15 Advanced Cardiovascular Systems, Inc. Abluminal stent coating apparatus and method using a brush assembly
US8609123B2 (en) * 2004-11-29 2013-12-17 Advanced Cardiovascular Systems, Inc. Derivatized poly(ester amide) as a biobeneficial coating
US7892592B1 (en) 2004-11-30 2011-02-22 Advanced Cardiovascular Systems, Inc. Coating abluminal surfaces of stents and other implantable medical devices
US20060115449A1 (en) * 2004-11-30 2006-06-01 Advanced Cardiovascular Systems, Inc. Bioabsorbable, biobeneficial, tyrosine-based polymers for use in drug eluting stent coatings
SE0403014D0 (sv) * 2004-12-10 2004-12-10 Straumann Holding Ag New protein formulation
WO2006064381A2 (en) 2004-12-10 2006-06-22 Straumann Holding Ag Protein formulation
EP1862170B1 (de) 2004-12-10 2012-03-14 Straumann Holding AG Emailleformulierung mit Amelogenin
US20090264939A9 (en) * 2004-12-16 2009-10-22 Martz Erik O Instrument set and method for performing spinal nuclectomy
US7854944B2 (en) 2004-12-17 2010-12-21 Advanced Cardiovascular Systems, Inc. Tissue regeneration
WO2006069344A2 (en) * 2004-12-22 2006-06-29 Rutgers, The State University Of New Jersey Controlled release hydrogels
EP1828244A2 (de) * 2004-12-22 2007-09-05 Kuros Biosurgery AG Synthetische biologische materialien mit darin über enzymatisch abbaubare bindungen eingearbeiteten biologisch aktiven faktoren
US7604818B2 (en) * 2004-12-22 2009-10-20 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrocarbon monomers
US7419504B2 (en) * 2004-12-27 2008-09-02 Advanced Cardiovascular Systems, Inc. Poly(ester amide) block copolymers
US8007775B2 (en) 2004-12-30 2011-08-30 Advanced Cardiovascular Systems, Inc. Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
WO2006073711A2 (en) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
KR20070108170A (ko) * 2005-01-06 2007-11-08 쿠로스 바이오서저리 아게 골절 복구용 보충된 매트릭스
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
US7202325B2 (en) * 2005-01-14 2007-04-10 Advanced Cardiovascular Systems, Inc. Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles
US7611494B2 (en) 2005-02-08 2009-11-03 Confluent Surgical, Inc. Spray for fluent materials
AU2006213822B2 (en) 2005-02-09 2011-05-26 Covidien Lp Synthetic sealants
CA2596506C (en) 2005-02-09 2021-04-06 Avi Biopharma, Inc. Antisense composition and method for treating muscle atrophy
EP1858955A1 (de) * 2005-02-23 2007-11-28 E.I. Dupont De Nemours And Company Verfahren mit alpha-, omega-difunktionellen aldaramiden als monomere und vernetzer
JP2008531769A (ja) * 2005-02-23 2008-08-14 ズィマー・テクノロジー・インコーポレーテッド ブレンドヒドロゲルおよびその製造方法
WO2006099137A1 (en) * 2005-03-10 2006-09-21 Uab Research Foundation Endothelial predecessor cell seeded wound healing scaffold
US7579317B2 (en) * 2005-03-11 2009-08-25 Keratec, Ltd. Nutraceutical composition comprising soluble keratin or derivative thereof
US9364229B2 (en) 2005-03-15 2016-06-14 Covidien Lp Circular anastomosis structures
US20090062184A1 (en) * 2005-03-24 2009-03-05 Dainippon Sumitomo Pharma Co., Ltd. Fine particulate preparation comprising complex of nucleic acid molecule and collagen
US20060222596A1 (en) * 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
JP2008534640A (ja) 2005-04-05 2008-08-28 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー タンパク質の機能部位またはエピトープの遮蔽方法
US7381048B2 (en) * 2005-04-12 2008-06-03 Advanced Cardiovascular Systems, Inc. Stents with profiles for gripping a balloon catheter and molds for fabricating stents
US8303972B2 (en) * 2005-04-19 2012-11-06 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US8187621B2 (en) 2005-04-19 2012-05-29 Advanced Cardiovascular Systems, Inc. Methods and compositions for treating post-myocardial infarction damage
US8828433B2 (en) 2005-04-19 2014-09-09 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US20080125745A1 (en) 2005-04-19 2008-05-29 Shubhayu Basu Methods and compositions for treating post-cardial infarction damage
US9539410B2 (en) 2005-04-19 2017-01-10 Abbott Cardiovascular Systems Inc. Methods and compositions for treating post-cardial infarction damage
US7795467B1 (en) 2005-04-26 2010-09-14 Advanced Cardiovascular Systems, Inc. Bioabsorbable, biobeneficial polyurethanes for use in medical devices
US8414907B2 (en) 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US9119901B2 (en) 2005-04-28 2015-09-01 Warsaw Orthopedic, Inc. Surface treatments for promoting selective tissue attachment to medical impants
US8778375B2 (en) 2005-04-29 2014-07-15 Advanced Cardiovascular Systems, Inc. Amorphous poly(D,L-lactide) coating
US20060253199A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Lordosis creating nucleus replacement method and apparatus
US20060253198A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Multi-lumen mold for intervertebral prosthesis and method of using same
US7291166B2 (en) * 2005-05-18 2007-11-06 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
US9505867B2 (en) * 2005-05-31 2016-11-29 Ecole Polytechmique Fédérale De Lausanne Triblock copolymers for cytoplasmic delivery of gene-based drugs
US7823533B2 (en) 2005-06-30 2010-11-02 Advanced Cardiovascular Systems, Inc. Stent fixture and method for reducing coating defects
US8021676B2 (en) 2005-07-08 2011-09-20 Advanced Cardiovascular Systems, Inc. Functionalized chemically inert polymers for coatings
EP2412744B1 (de) * 2005-07-18 2014-01-22 Nektar Therapeutics Verfahren zur Herstellung von verzweigten funktionalisierten Polymeren mithilfe von verzweigten Polyol-Kernen
US7785647B2 (en) 2005-07-25 2010-08-31 Advanced Cardiovascular Systems, Inc. Methods of providing antioxidants to a drug containing product
US7735449B1 (en) 2005-07-28 2010-06-15 Advanced Cardiovascular Systems, Inc. Stent fixture having rounded support structures and method for use thereof
US7658880B2 (en) 2005-07-29 2010-02-09 Advanced Cardiovascular Systems, Inc. Polymeric stent polishing method and apparatus
US7297758B2 (en) * 2005-08-02 2007-11-20 Advanced Cardiovascular Systems, Inc. Method for extending shelf-life of constructs of semi-crystallizable polymers
WO2007016622A2 (en) * 2005-08-02 2007-02-08 Wright Medical Technolody, Inc. Gel composition for inhibiting cellular adhesion
US20070031467A1 (en) * 2005-08-04 2007-02-08 Abrahams John M Composition and method for vascular embolization
US20070031468A1 (en) * 2005-08-04 2007-02-08 Endomedix, Inc. Modified chitosan for vascular embolization
US20070038290A1 (en) * 2005-08-15 2007-02-15 Bin Huang Fiber reinforced composite stents
US7476245B2 (en) * 2005-08-16 2009-01-13 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
US9248034B2 (en) * 2005-08-23 2016-02-02 Advanced Cardiovascular Systems, Inc. Controlled disintegrating implantable medical devices
US8679537B2 (en) * 2005-08-24 2014-03-25 Actamaz Surgical Materials, LLC Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive
US8679536B2 (en) * 2005-08-24 2014-03-25 Actamax Surgical Materials, Llc Aldol-crosslinked polymeric hydrogel adhesives
US8480757B2 (en) * 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
EP1937701A4 (de) * 2005-09-02 2009-09-16 Colbar Lifescience Ltd Quervernetzte polysaccharid- und proteinmatrizen und verfahren zu ihrer herstellung
CA2518298A1 (fr) * 2005-09-06 2007-03-06 Chaimed Technologies Inc. Polymeres biodegradables, leur preparation et leur usage pour la fabrication de pansements
CN101305052B (zh) * 2005-09-09 2012-10-10 渥太华健康研究所 互穿网络和相关方法及组合物
EP1764117A1 (de) * 2005-09-20 2007-03-21 Zimmer GmbH Implantat zur Wiederherstellung von Knorpeldefekten und Verfahren zu seiner Herstellung
US20070071790A1 (en) * 2005-09-28 2007-03-29 Northwestern University Biodegradable nanocomposites with enhance mechanical properties for soft tissue
US8083726B1 (en) 2005-09-30 2011-12-27 Advanced Cardiovascular Systems, Inc. Encapsulating cells and lumen
US7544754B2 (en) 2005-09-30 2009-06-09 3M Innovative Properties Company Crosslinked polymers with amine binding groups
US7544755B2 (en) * 2005-09-30 2009-06-09 3M Innovative Properties Company Crosslinked polymers with amine binding groups
US7544756B2 (en) * 2005-09-30 2009-06-09 3M Innovative Properties Company Crosslinked polymers with amine binding groups
AU2006321914B2 (en) 2005-12-06 2012-01-19 Covidien Lp Bioabsorbable compounds and compositions containing them
CA2632120C (en) * 2005-12-07 2014-07-08 Zimmer, Inc. Methods of bonding or modifying hydrogels using irradiation
US20070135909A1 (en) * 2005-12-08 2007-06-14 Desnoyer Jessica R Adhesion polymers to improve stent retention
CA2629932C (en) * 2005-12-08 2014-07-08 Tyco Healthcare Group Lp Viscosity-reduced sprayable compositions
EP1960447A4 (de) * 2005-12-08 2010-12-01 Tyco Healthcare Biokompatible chirurgische zusammensetzungen
US7976891B1 (en) 2005-12-16 2011-07-12 Advanced Cardiovascular Systems, Inc. Abluminal stent coating apparatus and method of using focused acoustic energy
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
US20070142287A1 (en) * 2005-12-20 2007-06-21 Biomed Solutions, Llc Compositions And Methods For Treatment Of Cancer
CN1985778B (zh) * 2005-12-20 2010-10-13 广东冠昊生物科技股份有限公司 生物型人工角膜
US8017107B2 (en) 2005-12-22 2011-09-13 Zimmer, Inc. Perfluorocyclobutane crosslinked hydrogels
US8801790B2 (en) * 2005-12-27 2014-08-12 Warsaw Orthopedic, Inc. Intervertebral disc augmentation and rehydration with superabsorbent polymers
US20070149641A1 (en) * 2005-12-28 2007-06-28 Goupil Dennis W Injectable bone cement
US20070156230A1 (en) 2006-01-04 2007-07-05 Dugan Stephen R Stents with radiopaque markers
US7951185B1 (en) 2006-01-06 2011-05-31 Advanced Cardiovascular Systems, Inc. Delivery of a stent at an elevated temperature
CA2635374C (en) 2006-01-11 2015-12-08 Hyperbranch Medical Technology, Inc. Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices
US20070179219A1 (en) * 2006-01-31 2007-08-02 Bin Huang Method of fabricating an implantable medical device using gel extrusion and charge induced orientation
CA2640629A1 (en) 2006-02-03 2007-08-09 Tissuemed Limited Tissue-adhesive materials
EP1988847B1 (de) 2006-02-08 2014-08-13 Northwestern University Funktionalisierende implantierbare vorrichtungen mit einem poly-(diol-ko-zitrat)-polymer
US20070191931A1 (en) * 2006-02-16 2007-08-16 Jan Weber Bioerodible endoprostheses and methods of making the same
US20070196428A1 (en) 2006-02-17 2007-08-23 Thierry Glauser Nitric oxide generating medical devices
US20090018575A1 (en) * 2006-03-01 2009-01-15 Tissuemed Limited Tissue-adhesive formulations
US7713637B2 (en) 2006-03-03 2010-05-11 Advanced Cardiovascular Systems, Inc. Coating containing PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid polymer
US8110242B2 (en) 2006-03-24 2012-02-07 Zimmer, Inc. Methods of preparing hydrogel coatings
US8795709B2 (en) * 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
US7964210B2 (en) * 2006-03-31 2011-06-21 Abbott Cardiovascular Systems Inc. Degradable polymeric implantable medical devices with a continuous phase and discrete phase
US7883520B2 (en) 2006-04-10 2011-02-08 Forsight Labs, Llc Corneal epithelial pocket formation systems, components and methods
US20120035437A1 (en) 2006-04-12 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Navigation of a lumen traveling device toward a target
US20070243130A1 (en) * 2006-04-18 2007-10-18 Weiliam Chen Biopolymer system for tissue sealing
US20080075657A1 (en) * 2006-04-18 2008-03-27 Abrahams John M Biopolymer system for tissue sealing
US7854923B2 (en) 2006-04-18 2010-12-21 Endomedix, Inc. Biopolymer system for tissue sealing
US8747870B2 (en) 2006-04-20 2014-06-10 University Of Utah Research Foundation Polymeric compositions and methods of making and using thereof
AU2007240613B2 (en) * 2006-04-20 2013-11-28 University Of Utah Research Foundation Polymeric compositions and methods of making and using thereof
CA2650473C (en) 2006-04-24 2013-06-18 Incept, Llc Protein crosslinkers, crosslinking methods and applications thereof
US8069814B2 (en) 2006-05-04 2011-12-06 Advanced Cardiovascular Systems, Inc. Stent support devices
US7985441B1 (en) 2006-05-04 2011-07-26 Yiwen Tang Purification of polymers for coating applications
US8304012B2 (en) 2006-05-04 2012-11-06 Advanced Cardiovascular Systems, Inc. Method for drying a stent
US7761968B2 (en) * 2006-05-25 2010-07-27 Advanced Cardiovascular Systems, Inc. Method of crimping a polymeric stent
US7775178B2 (en) 2006-05-26 2010-08-17 Advanced Cardiovascular Systems, Inc. Stent coating apparatus and method
US7951194B2 (en) 2006-05-26 2011-05-31 Abbott Cardiovascular Sysetms Inc. Bioabsorbable stent with radiopaque coating
US20130325107A1 (en) 2006-05-26 2013-12-05 Abbott Cardiovascular Systems Inc. Stents With Radiopaque Markers
US20070282434A1 (en) * 2006-05-30 2007-12-06 Yunbing Wang Copolymer-bioceramic composite implantable medical devices
US7872068B2 (en) * 2006-05-30 2011-01-18 Incept Llc Materials formable in situ within a medical device
US7959940B2 (en) 2006-05-30 2011-06-14 Advanced Cardiovascular Systems, Inc. Polymer-bioceramic composite implantable medical devices
US7842737B2 (en) 2006-09-29 2010-11-30 Abbott Cardiovascular Systems Inc. Polymer blend-bioceramic composite implantable medical devices
US8343530B2 (en) * 2006-05-30 2013-01-01 Abbott Cardiovascular Systems Inc. Polymer-and polymer blend-bioceramic composite implantable medical devices
US20080058916A1 (en) * 2006-05-31 2008-03-06 Bin Huang Method of fabricating polymeric self-expandable stent
US8568764B2 (en) * 2006-05-31 2013-10-29 Advanced Cardiovascular Systems, Inc. Methods of forming coating layers for medical devices utilizing flash vaporization
WO2007137839A2 (en) 2006-05-31 2007-12-06 Baxter International Inc. Method for directed cell in-growth and controlled tissue regeneration in spinal surgery
US9561351B2 (en) * 2006-05-31 2017-02-07 Advanced Cardiovascular Systems, Inc. Drug delivery spiral coil construct
US7820172B1 (en) 2006-06-01 2010-10-26 Biosurface Engineering Technologies, Inc. Laminin-derived multi-domain peptides
US8034287B2 (en) 2006-06-01 2011-10-11 Abbott Cardiovascular Systems Inc. Radiation sterilization of medical devices
US20070281073A1 (en) * 2006-06-01 2007-12-06 Gale David C Enhanced adhesion of drug delivery coatings on stents
US8486135B2 (en) 2006-06-01 2013-07-16 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from branched polymers
US8703167B2 (en) 2006-06-05 2014-04-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
US8778376B2 (en) 2006-06-09 2014-07-15 Advanced Cardiovascular Systems, Inc. Copolymer comprising elastin pentapeptide block and hydrophilic block, and medical device and method of treating
US8603530B2 (en) 2006-06-14 2013-12-10 Abbott Cardiovascular Systems Inc. Nanoshell therapy
US8114150B2 (en) 2006-06-14 2012-02-14 Advanced Cardiovascular Systems, Inc. RGD peptide attached to bioabsorbable stents
US8048448B2 (en) 2006-06-15 2011-11-01 Abbott Cardiovascular Systems Inc. Nanoshells for drug delivery
US8535372B1 (en) 2006-06-16 2013-09-17 Abbott Cardiovascular Systems Inc. Bioabsorbable stent with prohealing layer
US8333000B2 (en) 2006-06-19 2012-12-18 Advanced Cardiovascular Systems, Inc. Methods for improving stent retention on a balloon catheter
EP2046350A4 (de) 2006-06-22 2011-09-14 Biosurface Eng Tech Inc Zusammensetzungen und verfahren zur freisetzung eines bmp-2-amplifikators/coaktivators für verstärkte osteogenese
US8017237B2 (en) 2006-06-23 2011-09-13 Abbott Cardiovascular Systems, Inc. Nanoshells on polymers
US9072820B2 (en) 2006-06-26 2015-07-07 Advanced Cardiovascular Systems, Inc. Polymer composite stent with polymer particles
US8128688B2 (en) 2006-06-27 2012-03-06 Abbott Cardiovascular Systems Inc. Carbon coating on an implantable device
US7794776B1 (en) 2006-06-29 2010-09-14 Abbott Cardiovascular Systems Inc. Modification of polymer stents with radiation
US7960498B2 (en) * 2006-06-30 2011-06-14 Actamax Surgical Materials, Llc Tissue adhesives with modified elasticity
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US7740791B2 (en) 2006-06-30 2010-06-22 Advanced Cardiovascular Systems, Inc. Method of fabricating a stent with features by blow molding
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
US20080009938A1 (en) * 2006-07-07 2008-01-10 Bin Huang Stent with a radiopaque marker and method for making the same
US7823263B2 (en) 2006-07-11 2010-11-02 Abbott Cardiovascular Systems Inc. Method of removing stent islands from a stent
EP2038309A2 (de) * 2006-07-11 2009-03-25 University of Utah Research Foundation Mit elektrophilen gruppen modifizierte makromoleküle sowie verfahren zu ihrer herstellung und verwendung
US20080014244A1 (en) * 2006-07-13 2008-01-17 Gale David C Implantable medical devices and coatings therefor comprising physically crosslinked block copolymers
US7757543B2 (en) * 2006-07-13 2010-07-20 Advanced Cardiovascular Systems, Inc. Radio frequency identification monitoring of stents
US7998404B2 (en) 2006-07-13 2011-08-16 Advanced Cardiovascular Systems, Inc. Reduced temperature sterilization of stents
US8685430B1 (en) 2006-07-14 2014-04-01 Abbott Cardiovascular Systems Inc. Tailored aliphatic polyesters for stent coatings
US7794495B2 (en) 2006-07-17 2010-09-14 Advanced Cardiovascular Systems, Inc. Controlled degradation of stents
US7886419B2 (en) 2006-07-18 2011-02-15 Advanced Cardiovascular Systems, Inc. Stent crimping apparatus and method
US7732190B2 (en) * 2006-07-31 2010-06-08 Advanced Cardiovascular Systems, Inc. Modified two-component gelation systems, methods of use and methods of manufacture
US8016879B2 (en) 2006-08-01 2011-09-13 Abbott Cardiovascular Systems Inc. Drug delivery after biodegradation of the stent scaffolding
WO2008015319A1 (fr) 2006-08-02 2008-02-07 Khorionyx Preparation implantable, utilisable notamment pour le complement tissulaire et la cicatrisation
TWI436793B (zh) * 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
US8129445B2 (en) * 2006-08-09 2012-03-06 Ethicon, Inc. Moisture activated latent curing adhesive or sealant
US7947758B2 (en) * 2006-08-09 2011-05-24 Ethicon, Inc. Moisture activated latent curing adhesive or sealant
US8703169B1 (en) 2006-08-15 2014-04-22 Abbott Cardiovascular Systems Inc. Implantable device having a coating comprising carrageenan and a biostable polymer
US9173733B1 (en) 2006-08-21 2015-11-03 Abbott Cardiovascular Systems Inc. Tracheobronchial implantable medical device and methods of use
US9242005B1 (en) 2006-08-21 2016-01-26 Abbott Cardiovascular Systems Inc. Pro-healing agent formulation compositions, methods and treatments
US7923022B2 (en) * 2006-09-13 2011-04-12 Advanced Cardiovascular Systems, Inc. Degradable polymeric implantable medical devices with continuous phase and discrete phase
US7985783B2 (en) 2006-09-21 2011-07-26 The Regents Of The University Of California Aldehyde tags, uses thereof in site-specific protein modification
US8557929B2 (en) 2006-09-29 2013-10-15 Nof Corporation Method for producing biodegradable polyoxyalkylene derivative
US7592009B2 (en) * 2006-10-10 2009-09-22 Ecole Polytechnique Federale De Lausanne (Epfl) Polypeptide ligands for targeting cartilage and methods of use thereof
JP2008093230A (ja) * 2006-10-13 2008-04-24 Kanagawa Acad Of Sci & Technol ゲル形成用組成物
US7845533B2 (en) 2007-06-22 2010-12-07 Tyco Healthcare Group Lp Detachable buttress material retention systems for use with a surgical stapling device
EP2077718B2 (de) 2006-10-27 2022-03-09 Edwards Lifesciences Corporation Biologisches gewebe für chirurgische implantation
US8580192B2 (en) 2006-10-31 2013-11-12 Ethicon, Inc. Sterilization of polymeric materials
US8741326B2 (en) * 2006-11-17 2014-06-03 Abbott Cardiovascular Systems Inc. Modified two-component gelation systems, methods of use and methods of manufacture
US9005672B2 (en) 2006-11-17 2015-04-14 Abbott Cardiovascular Systems Inc. Methods of modifying myocardial infarction expansion
US8282959B2 (en) * 2006-11-27 2012-10-09 Actamax Surgical Materials, Llc Branched end reactants and polymeric hydrogel tissue adhesives therefrom
US8080593B2 (en) * 2006-11-29 2011-12-20 University Of Southern California Reversible thermoresponsive adhesives for implants
US8192760B2 (en) 2006-12-04 2012-06-05 Abbott Cardiovascular Systems Inc. Methods and compositions for treating tissue using silk proteins
DK2099400T3 (da) * 2006-12-06 2014-10-20 Weber Jeffrey A Knoglehulrumsfyldstof og fremgangsmåde til fremstilling deraf
CA2672529A1 (en) * 2006-12-11 2008-06-19 Keratec, Ltd. Porous keratin construct and method of making the same
US8597673B2 (en) 2006-12-13 2013-12-03 Advanced Cardiovascular Systems, Inc. Coating of fast absorption or dissolution
US8099849B2 (en) 2006-12-13 2012-01-24 Abbott Cardiovascular Systems Inc. Optimizing fracture toughness of polymeric stent
US20080159975A1 (en) * 2006-12-20 2008-07-03 Sunbio, Inc. Hair treatment composition, hair treatment agent and method for treating hair by using the same
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US20080154233A1 (en) * 2006-12-20 2008-06-26 Zimmer Orthobiologics, Inc. Apparatus for delivering a biocompatible material to a surgical site and method of using same
US7720533B2 (en) * 2006-12-20 2010-05-18 Zimmer Orthobiologicals, Inc. Apparatus and method for delivering a biocompatible material to a surgical site
US8105375B2 (en) * 2007-01-19 2012-01-31 The Cleveland Clinic Foundation Method for implanting a cardiovascular valve
WO2008094663A2 (en) * 2007-01-31 2008-08-07 Adam Heller Electrochemical management of pain
WO2008097901A1 (en) * 2007-02-02 2008-08-14 Tornier, Inc. System and method for repairing tendons and ligaments
CA2677532A1 (en) * 2007-02-06 2008-08-14 Incept, Llc Polymerization with precipitation of proteins for elution in physiological solution
US20080220047A1 (en) 2007-03-05 2008-09-11 Sawhney Amarpreet S Low-swelling biocompatible hydrogels
US20090227689A1 (en) 2007-03-05 2009-09-10 Bennett Steven L Low-Swelling Biocompatible Hydrogels
US20090227981A1 (en) 2007-03-05 2009-09-10 Bennett Steven L Low-Swelling Biocompatible Hydrogels
CA2680148C (en) 2007-03-06 2015-09-01 Tyco Healthcare Group Lp Surgical stapling apparatus
US20080243228A1 (en) * 2007-03-28 2008-10-02 Yunbing Wang Implantable medical devices fabricated from block copolymers
CA2682190C (en) * 2007-03-29 2015-01-27 Tyrx Pharma, Inc. Biodegradable, polymer coverings for breast implants
US9693841B2 (en) 2007-04-02 2017-07-04 Ension, Inc. Surface treated staples, sutures and dental floss and methods of manufacturing the same
US8262723B2 (en) 2007-04-09 2012-09-11 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from polymer blends with star-block copolymers
US8093039B2 (en) * 2007-04-10 2012-01-10 The Trustees Of The Stevens Institute Of Technology Surfaces differentially adhesive to eukaryotic cells and non-eukaryotic cells
WO2008128075A1 (en) 2007-04-12 2008-10-23 Isto Technologies, Inc. Compositions and methods for tissue repair
PL2136850T3 (pl) * 2007-04-13 2012-07-31 Kuros Biosurgery Ag Polimeryczny uszczelniacz tkankowy
US8147769B1 (en) 2007-05-16 2012-04-03 Abbott Cardiovascular Systems Inc. Stent and delivery system with reduced chemical degradation
US20080287633A1 (en) * 2007-05-18 2008-11-20 Drumheller Paul D Hydrogel Materials
US20080287986A1 (en) * 2007-05-18 2008-11-20 Possis Medical, Inc. Closure device
EP2152743A2 (de) * 2007-05-23 2010-02-17 Allergan, Inc. Quervernetztes collagen und anwendungen davon
US20080317826A1 (en) * 2007-05-24 2008-12-25 Robert James Kelly Porous keratin constructs, wound healing assemblies and methods using the same
US9199002B2 (en) * 2007-05-24 2015-12-01 The Trustees Of Columbia University In The City Of New York Hybrid soft tissue implants from progenitor cells and biomaterials
US9056155B1 (en) 2007-05-29 2015-06-16 Abbott Cardiovascular Systems Inc. Coatings having an elastic primer layer
US7829008B2 (en) * 2007-05-30 2010-11-09 Abbott Cardiovascular Systems Inc. Fabricating a stent from a blow molded tube
US7959857B2 (en) 2007-06-01 2011-06-14 Abbott Cardiovascular Systems Inc. Radiation sterilization of medical devices
US8202528B2 (en) * 2007-06-05 2012-06-19 Abbott Cardiovascular Systems Inc. Implantable medical devices with elastomeric block copolymer coatings
US20080306582A1 (en) * 2007-06-05 2008-12-11 Yunbing Wang Implantable medical devices with elastomeric copolymer coatings
US8293260B2 (en) 2007-06-05 2012-10-23 Abbott Cardiovascular Systems Inc. Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices
US8425591B1 (en) 2007-06-11 2013-04-23 Abbott Cardiovascular Systems Inc. Methods of forming polymer-bioceramic composite medical devices with bioceramic particles
US8133553B2 (en) 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US7665646B2 (en) 2007-06-18 2010-02-23 Tyco Healthcare Group Lp Interlocking buttress material retention system
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
US8048441B2 (en) 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
US8109904B1 (en) 2007-06-25 2012-02-07 Abbott Cardiovascular Systems Inc. Drug delivery medical devices
US8933290B2 (en) * 2007-06-26 2015-01-13 Sofradim Production Sas Mesh implant
US7901452B2 (en) 2007-06-27 2011-03-08 Abbott Cardiovascular Systems Inc. Method to fabricate a stent having selected morphology to reduce restenosis
US7955381B1 (en) 2007-06-29 2011-06-07 Advanced Cardiovascular Systems, Inc. Polymer-bioceramic composite implantable medical device with different types of bioceramic particles
US9125807B2 (en) * 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
CA2696996C (en) 2007-07-16 2016-03-22 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Antimicrobial constructs
JP2010534515A (ja) * 2007-07-23 2010-11-11 ハイパーブランチ メディカル テクノロジー, インコーポレイテッド 創傷部位を被覆するための重合マスキング材料、およびその使用方法
ES2365290T3 (es) * 2007-07-25 2011-09-28 Alcon, Inc. Materiales para dispositivo oftálmico de alto índice de refracción.
US20090035249A1 (en) * 2007-08-02 2009-02-05 Bhatia Sujata K Method of inhibiting proliferation of Escherichia coli
US7731988B2 (en) 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
GB0715514D0 (en) * 2007-08-10 2007-09-19 Tissuemed Ltd Coated medical devices
US8067028B2 (en) * 2007-08-13 2011-11-29 Confluent Surgical Inc. Drug delivery device
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US8608049B2 (en) 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
EP2214734B1 (de) 2007-10-30 2017-12-13 Baxter International Inc. Verwendung einer regenerativen biofunktionalen kollagen-biomatrix zur behandlung von viszeralen oder parietalen defekten
US20090123519A1 (en) * 2007-11-12 2009-05-14 Surmodics, Inc. Swellable hydrogel matrix and methods
EP2214731B1 (de) * 2007-11-14 2014-05-14 Actamax Surgical Materials LLC Auf oxidiertem kationischem polysaccharid basierendes polymergewebehaftmittel zur medizinischen verwendung
US7947784B2 (en) 2007-11-16 2011-05-24 Zimmer, Inc. Reactive compounding of hydrogels
EP2987510B1 (de) 2007-11-21 2020-10-28 T.J. Smith & Nephew Limited Saugvorrichtung und verband
CN101868203B (zh) 2007-11-21 2014-10-22 史密夫及内修公开有限公司 伤口包敷物
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
US8299316B2 (en) 2007-12-18 2012-10-30 Ethicon, Inc. Hemostatic device
US8629314B2 (en) * 2007-12-18 2014-01-14 Ethicon, Inc. Surgical barriers having adhesion inhibiting properties
US8211489B2 (en) 2007-12-19 2012-07-03 Abbott Cardiovascular Systems, Inc. Methods for applying an application material to an implantable device
US8361538B2 (en) 2007-12-19 2013-01-29 Abbott Laboratories Methods for applying an application material to an implantable device
EP2237770A4 (de) 2007-12-26 2011-11-09 Gel Del Technologies Inc Biokompatible proteinteilchen, teilchenvorrichtungen und verfahren dafür
JP2012512812A (ja) * 2007-12-28 2012-06-07 クロス・バイオサージェリー・アクチェンゲゼルシャフト フィブリンフォームに組込まれたpdgf融合タンパク質
US8034362B2 (en) * 2008-01-04 2011-10-11 Zimmer, Inc. Chemical composition of hydrogels for use as articulating surfaces
US7862538B2 (en) * 2008-02-04 2011-01-04 Incept Llc Surgical delivery system for medical sealant
US9034002B2 (en) 2008-02-18 2015-05-19 Covidien Lp Lock bar spring and clip for implant deployment device
US8808314B2 (en) 2008-02-18 2014-08-19 Covidien Lp Device and method for deploying and attaching an implant to a biological tissue
US8317808B2 (en) 2008-02-18 2012-11-27 Covidien Lp Device and method for rolling and inserting a prosthetic patch into a body cavity
EP2247245B1 (de) 2008-02-18 2017-06-28 Covidien LP Vorrichtung zur ablage und befestigung eines pflasters auf biologischem gewebe
US9398944B2 (en) 2008-02-18 2016-07-26 Covidien Lp Lock bar spring and clip for implant deployment device
US9301826B2 (en) 2008-02-18 2016-04-05 Covidien Lp Lock bar spring and clip for implant deployment device
US9044235B2 (en) 2008-02-18 2015-06-02 Covidien Lp Magnetic clip for implant deployment device
US9393002B2 (en) 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
US9393093B2 (en) 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
US8758373B2 (en) 2008-02-18 2014-06-24 Covidien Lp Means and method for reversibly connecting a patch to a patch deployment device
US9833240B2 (en) 2008-02-18 2017-12-05 Covidien Lp Lock bar spring and clip for implant deployment device
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
JP5569398B2 (ja) 2008-02-29 2014-08-13 フェッローサン メディカル ディバイス エー/エス 止血および/または創傷治癒を促進するための装置
US8293813B2 (en) * 2008-03-05 2012-10-23 Biomet Manufacturing Corporation Cohesive and compression resistant demineralized bone carrier matrix
DK2280720T3 (en) 2008-03-27 2019-06-11 Purdue Research Foundation COLLAGEN BINDING SYNTHETIC PEPTIDOGLYCANES, MANUFACTURING AND PROCEDURE FOR USE
DE202008005131U1 (de) 2008-04-14 2008-08-28 Eidgenössische Technische Hochschule Zürich Synthetische Matrix für das gesteuerte Einwachsen von Zellen und Geweberegeneration
EP2285866A2 (de) * 2008-04-22 2011-02-23 Angiotech Pharmaceuticals, Inc. Biokompatible vernetzte hydrogele, arzneistoffbeladene hydrogele und herstellungsverfahren dafür
EP2310002B1 (de) 2008-04-24 2016-11-02 Medtronic, Inc Schutzgel auf basis von chitosan und oxidiertem polysaccharid
JP2011518837A (ja) * 2008-04-24 2011-06-30 メドトロニック,インコーポレイテッド 再水和可能なチオール化多糖粒子およびスポンジ
JP5653342B2 (ja) 2008-04-24 2015-01-14 メドトロニック,インコーポレイテッド 冷間電離放射線滅菌
JP5711113B2 (ja) * 2008-04-24 2015-04-30 メドトロニック,インコーポレイテッド チオール化キトサンゲル
KR101464983B1 (ko) 2008-05-01 2014-11-25 스파인셀 프러프라이어테리 리미티드 조직 보형물의 형성 및 삽입기구 및 그의 시스템 및 방법
TW201000155A (en) 2008-05-06 2010-01-01 Alcon Inc High refractive index ophthalmic device materials
US8207264B2 (en) * 2008-07-11 2012-06-26 Tyco Healthcare Group Lp Functionalized inclusion complexes as crosslinkers
US8551136B2 (en) 2008-07-17 2013-10-08 Actamax Surgical Materials, Llc High swell, long-lived hydrogel sealant
US20100015231A1 (en) * 2008-07-17 2010-01-21 E.I. Du Pont De Nemours And Company Low swell, long-lived hydrogel sealant
US9271706B2 (en) 2008-08-12 2016-03-01 Covidien Lp Medical device for wound closure and method of use
US9943302B2 (en) 2008-08-12 2018-04-17 Covidien Lp Medical device for wound closure and method of use
WO2010043979A2 (en) * 2008-10-17 2010-04-22 Sofradim Production Auto-sealant matrix for tissue repair
US20100100123A1 (en) * 2008-10-17 2010-04-22 Confluent Surgical, Inc. Hemostatic implant
US9889230B2 (en) * 2008-10-17 2018-02-13 Covidien Lp Hemostatic implant
CA2730547C (en) 2008-10-20 2013-08-06 Polytouch Medical Ltd. A device for attaching a patch to a biological tissue
US8466327B2 (en) 2008-11-19 2013-06-18 Actamax Surgical Materials, Llc Aldehyde-functionalized polyethers and method of making same
US9044529B2 (en) * 2008-11-19 2015-06-02 Actamax Surgical Materials, Llc Hydrogel tissue adhesive formed from aminated polysaccharide and aldehyde-functionalized multi-arm polyether
JP5814793B2 (ja) 2008-11-25 2015-11-17 エコール ポリテクニク フェデラル ド ローザンヌ(エーペーエフエル) ブロックコポリマーおよびその使用
US20100147921A1 (en) 2008-12-16 2010-06-17 Lee Olson Surgical Apparatus Including Surgical Buttress
WO2010070775A1 (ja) * 2008-12-19 2010-06-24 株式会社ネクスト21 超高強度インジェクタブルハイドロゲル及びその製造方法
US20100160960A1 (en) * 2008-12-19 2010-06-24 E. I. Du Pont De Nemours And Company Hydrogel tissue adhesive having increased degradation time
EP2396070A4 (de) 2009-02-12 2012-09-19 Incept Llc Wirkstofffreisetzung mit hydrogel-plugs
CN102123652B (zh) 2009-02-18 2013-09-11 奥林巴斯医疗株式会社 内窥镜插入装置
US9486215B2 (en) 2009-03-31 2016-11-08 Covidien Lp Surgical stapling apparatus
US20100261652A1 (en) * 2009-04-08 2010-10-14 California Institute Of Technology Tissue Adhesive Using Engineered Proteins
EP2416811B1 (de) 2009-04-09 2015-09-09 Actamax Surgical Materials LLC Hydrogel-gewebekleber mit verringerter zerfallszeit
EP2424447A2 (de) 2009-05-01 2012-03-07 Endologix, Inc. Perkutanes verfahren und vorrichtung zur behandlung von dissektionen
US10772717B2 (en) 2009-05-01 2020-09-15 Endologix, Inc. Percutaneous method and device to treat dissections
CA2760704C (en) * 2009-05-04 2017-10-03 Incept, Llc Biomaterials for track and puncture closure
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
KR101699992B1 (ko) * 2009-06-16 2017-01-26 백스터 인터내셔널 인코포레이티드 지혈용 스펀지
US8796242B2 (en) 2009-07-02 2014-08-05 Actamax Surgical Materials, Llc Hydrogel tissue adhesive for medical use
EP2448604B1 (de) 2009-07-02 2016-03-23 Actamax Surgical Materials LLC Hydrogel-gewebekleber zum medizinischen gebrauch
WO2011002956A1 (en) 2009-07-02 2011-01-06 E. I. Du Pont De Nemours And Company Aldehyde-functionalized polysaccharides
US8580950B2 (en) 2009-07-02 2013-11-12 Actamax Surgical Materials, Llc Aldehyde-functionalized polysaccharides
JP5588511B2 (ja) 2009-07-27 2014-09-10 エンドロジックス、インク ステントグラフト
AU2010276574B2 (en) 2009-07-30 2015-08-20 Carbylan Therapeutics, Inc. Modified hyaluronic acid polymer compositions and related methods
US20110033515A1 (en) * 2009-08-04 2011-02-10 Rst Implanted Cell Technology Tissue contacting material
US8906045B2 (en) 2009-08-17 2014-12-09 Covidien Lp Articulating patch deployment device and method of use
WO2011021082A1 (en) 2009-08-17 2011-02-24 PolyTouch Medical, Inc. Means and method for reversibly connecting an implant to a deployment device
WO2011025893A1 (en) 2009-08-28 2011-03-03 The Trustees Of Columbia University In The City Of New York Systems, methods, and devices for production of gas-filled microbubbles
JP2011052051A (ja) * 2009-08-31 2011-03-17 Jsr Corp 接着剤組成物、それを用いた基材の加工または移動方法および半導体素子
US20110081398A1 (en) 2009-10-01 2011-04-07 Tyco Healthcare Group Lp Multi-mechanism surgical compositions
US8470355B2 (en) * 2009-10-01 2013-06-25 Covidien Lp Mesh implant
US20110081701A1 (en) * 2009-10-02 2011-04-07 Timothy Sargeant Surgical compositions
US20110091427A1 (en) * 2009-10-02 2011-04-21 Baxter International Inc. Methods for treating a kidney injury
US8968785B2 (en) * 2009-10-02 2015-03-03 Covidien Lp Surgical compositions
US8617206B2 (en) 2009-10-08 2013-12-31 Covidien Lp Wound closure device
US20110087274A1 (en) 2009-10-08 2011-04-14 Tyco Healtcare Group LP, New Haven, Ct Wound Closure Device
US20110087273A1 (en) * 2009-10-08 2011-04-14 Tyco Healthcare Group Lp Wound Closure Device
US9833225B2 (en) 2009-10-08 2017-12-05 Covidien Lp Wound closure device
US10293553B2 (en) 2009-10-15 2019-05-21 Covidien Lp Buttress brachytherapy and integrated staple line markers for margin identification
US20150231409A1 (en) 2009-10-15 2015-08-20 Covidien Lp Buttress brachytherapy and integrated staple line markers for margin identification
US20110093057A1 (en) * 2009-10-16 2011-04-21 Confluent Surgical, Inc. Mitigating Thrombus Formation On Medical Devices By Influencing pH Microenvironment Near The Surface
US9445795B2 (en) 2009-10-16 2016-09-20 Confluent Surgical, Inc. Prevention of premature gelling of delivery devices for pH dependent forming materials
US9132207B2 (en) * 2009-10-27 2015-09-15 Spine Wave, Inc. Radiopaque injectable nucleus hydrogel compositions
US8138236B2 (en) * 2009-10-29 2012-03-20 Ethicon, Inc. Solvent-free moisture activated latent curing surgical adhesive or sealant
CN102695500A (zh) 2009-11-09 2012-09-26 聚光灯技术合伙有限责任公司 多糖基水凝胶
JP2013509963A (ja) 2009-11-09 2013-03-21 スポットライト テクノロジー パートナーズ エルエルシー 断片化ヒドロゲル
US8858592B2 (en) 2009-11-24 2014-10-14 Covidien Lp Wound plugs
JP5820815B2 (ja) 2009-12-15 2015-11-24 インセプト・リミテッド・ライアビリティ・カンパニーIncept,Llc インプラントおよび生体分解性基準マーカー
AU2010339045B2 (en) 2009-12-16 2014-06-05 Baxter Healthcare S.A. Hemostatic sponge
US10010709B2 (en) 2009-12-16 2018-07-03 The Trustees Of Columbia University In The City Of New York Composition for on-demand ultrasound-triggered drug delivery
US9925140B2 (en) * 2009-12-22 2018-03-27 National Cheng Kung University Cell tissue gel containing collagen and hyaluronan
US8994666B2 (en) * 2009-12-23 2015-03-31 Colin J. Karpfinger Tactile touch-sensing interface system
FR2955258A1 (fr) * 2010-01-20 2011-07-22 Biopharmex Holding Ltd Composition injectable
US8568471B2 (en) 2010-01-30 2013-10-29 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds
US8808353B2 (en) 2010-01-30 2014-08-19 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds having a low crossing profile
US8592364B2 (en) * 2010-02-11 2013-11-26 Ecole Polytechnique Federale de Lausanne (“EPFL”) CCR7 ligand delivery and co-delivery in immunotherapy
US10065030B2 (en) 2010-02-23 2018-09-04 Viaderm Llc Vacuum assisted percutaneous appliance
US8679404B2 (en) 2010-03-05 2014-03-25 Edwards Lifesciences Corporation Dry prosthetic heart valve packaging system
CA2730598C (en) 2010-03-16 2018-03-13 Confluent Surgical, Inc. Modulating drug release rate by controlling the kinetics of the ph transition in hydrogels
JP5839814B2 (ja) * 2010-03-17 2016-01-06 グンゼ株式会社 Danceタンパク質含有徐放基材及び該徐放基材の製造方法
US8685433B2 (en) 2010-03-31 2014-04-01 Abbott Cardiovascular Systems Inc. Absorbable coating for implantable device
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
US8362177B1 (en) 2010-05-05 2013-01-29 Novartis Ag High refractive index ophthalmic device materials with reduced tack
WO2011140519A2 (en) 2010-05-07 2011-11-10 Medicus Biosciences, Llc In vivo gelling pharmaceutical pre-formulation
US8697111B2 (en) 2010-05-12 2014-04-15 Covidien Lp Osteochondral implant comprising osseous phase and chondral phase
US8945156B2 (en) 2010-05-19 2015-02-03 University Of Utah Research Foundation Tissue fixation
US8858577B2 (en) 2010-05-19 2014-10-14 University Of Utah Research Foundation Tissue stabilization system
US8968783B2 (en) 2010-05-27 2015-03-03 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8591950B2 (en) 2010-05-27 2013-11-26 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8754564B2 (en) 2010-05-27 2014-06-17 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8734824B2 (en) 2010-05-27 2014-05-27 Covidien LLP Hydrogel implants with varying degrees of crosslinking
US8591929B2 (en) 2010-05-27 2013-11-26 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8883185B2 (en) 2010-05-27 2014-11-11 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8734930B2 (en) 2010-05-27 2014-05-27 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8940335B2 (en) 2010-06-01 2015-01-27 Baxter International Inc. Process for making dry and stable hemostatic compositions
JP6289096B2 (ja) 2010-06-01 2018-03-07 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 乾燥した安定な止血組成物を作製するためのプロセス
CN103037847B (zh) 2010-06-01 2016-01-20 巴克斯特国际公司 用于制备干燥、稳定的止血组合物的方法
US9125633B2 (en) 2010-06-25 2015-09-08 Baxter International Inc. Device for mixing and dispensing of two-component reactive surgical sealant
US8672237B2 (en) 2010-06-25 2014-03-18 Baxter International Inc. Device for mixing and dispensing of two-component reactive surgical sealant
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
US8716204B2 (en) 2010-07-27 2014-05-06 Zimmer, Inc. Synthetic synovial fluid compositions and methods for making the same
KR102139022B1 (ko) 2010-07-30 2020-07-29 알콘 인코포레이티드 가교된 친수성 코팅을 갖는 실리콘 히드로겔 렌즈
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
JP5846404B2 (ja) * 2010-10-14 2016-01-20 国立研究開発法人産業技術総合研究所 光分解性ゲル、細胞培養器具、細胞配列・分別装置、細胞配列方法および細胞分別方法
US20140086975A1 (en) 2010-10-15 2014-03-27 Rutgers, The State University Of New Jersey Hydrogel formulation for dermal and ocular delivery
US9393100B2 (en) 2010-11-17 2016-07-19 Endologix, Inc. Devices and methods to treat vascular dissections
MX337627B (es) 2010-11-25 2016-03-10 Smith & Nephew Composiciones i-ii y productos y usos de la misma.
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
US9498317B2 (en) 2010-12-16 2016-11-22 Edwards Lifesciences Corporation Prosthetic heart valve delivery systems and packaging
US8518440B2 (en) 2010-12-21 2013-08-27 Confluent Surgical, Inc. Biodegradable osmotic pump implant for drug delivery
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
AU2012202543B9 (en) * 2011-01-04 2017-11-02 Gatt Technologies B.V. Cross-linked polymers and implants derived from electrophilically activated polyoxazoline
US8360765B2 (en) 2011-01-07 2013-01-29 Covidien Lp Systems and method for forming a coaxial implant
US8608775B2 (en) 2011-01-24 2013-12-17 Covidien Lp Two part tape adhesive for wound closure
US9084602B2 (en) 2011-01-26 2015-07-21 Covidien Lp Buttress film with hemostatic action for surgical stapling apparatus
US8852214B2 (en) 2011-02-04 2014-10-07 University Of Utah Research Foundation System for tissue fixation to bone
US8479968B2 (en) 2011-03-10 2013-07-09 Covidien Lp Surgical instrument buttress attachment
EP2686027B1 (de) 2011-03-16 2021-05-05 Kuros Biosurgery AG Pharmazeutische formulierung zur verwendung für die wirbelsäulenfusion
DE102011007528A1 (de) 2011-04-15 2012-10-18 Aesculap Aktiengesellschaft Thixotrope Zusammensetzung, insbesondere zur postchirurgischen Adhäsionsprophylaxe
KR102006036B1 (ko) 2011-05-24 2019-07-31 시믹 아이피, 엘엘씨 히알루론산-결합 합성 펩티도글리칸 및 이의 제조 및 이용 방법
US20120328557A1 (en) * 2011-06-23 2012-12-27 Excel Med, Llc Adhesive cell tissue gels
CN103619886B (zh) 2011-06-29 2016-09-14 柯惠Lp公司 氧化纤维素的溶解
AU2012278944B2 (en) 2011-07-05 2015-09-17 Bioasis Technologies Inc. p97-antibody conjugates and methods of use
US10865383B2 (en) 2011-07-12 2020-12-15 Lineage Cell Therapeutics, Inc. Methods and formulations for orthopedic cell therapy
US20130023736A1 (en) 2011-07-21 2013-01-24 Stanley Dale Harpstead Systems for drug delivery and monitoring
US8726483B2 (en) 2011-07-29 2014-05-20 Abbott Cardiovascular Systems Inc. Methods for uniform crimping and deployment of a polymer scaffold
US11083821B2 (en) 2011-08-10 2021-08-10 C.P. Medical Corporation Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
US10111985B2 (en) 2011-08-10 2018-10-30 Medicus Biosciences, Llc Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
EP2760431A1 (de) 2011-09-30 2014-08-06 Sofradim Production Mehrschichtige implantate zur verabreichung therapeutischer wirkstoffe
US10849931B2 (en) 2011-09-30 2020-12-01 Depuy Synthes Products, Inc Compositions and methods for platelet enriched fibrin constructs
US20130085139A1 (en) 2011-10-04 2013-04-04 Royal Holloway And Bedford New College Oligomers
CN103957949B (zh) 2011-10-11 2017-07-18 巴克斯特国际公司 止血组合物
CN103957948B (zh) 2011-10-11 2016-10-26 巴克斯特国际公司 止血组合物
HUE029018T2 (en) 2011-10-12 2017-02-28 Novartis Ag A method for producing UV absorbing contact lenses by coating
KR101975624B1 (ko) 2011-10-27 2019-05-07 백스터 인터내셔널 인코포레이티드 지혈 조성물
US8584920B2 (en) 2011-11-04 2013-11-19 Covidien Lp Surgical stapling apparatus including releasable buttress
RU2521194C2 (ru) * 2011-11-16 2014-06-27 Общество с ограниченной ответственностью предприятие "Репер" Матрица для клеточной трансплантологии
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
WO2013082548A1 (en) 2011-11-30 2013-06-06 Sarepta Therapeutics, Inc. Oligonucleotides for treating expanded repeat diseases
AU2012345638C1 (en) 2011-11-30 2018-10-18 Sarepta Therapeutics, Inc. Induced exon inclusion in spinal muscle atrophy
US9205150B2 (en) 2011-12-05 2015-12-08 Incept, Llc Medical organogel processes and compositions
US9113885B2 (en) 2011-12-14 2015-08-25 Covidien Lp Buttress assembly for use with surgical stapling device
US8967448B2 (en) 2011-12-14 2015-03-03 Covidien Lp Surgical stapling apparatus including buttress attachment via tabs
US9351731B2 (en) 2011-12-14 2016-05-31 Covidien Lp Surgical stapling apparatus including releasable surgical buttress
US9237892B2 (en) 2011-12-14 2016-01-19 Covidien Lp Buttress attachment to the cartridge surface
KR101444877B1 (ko) 2011-12-30 2014-10-01 주식회사 삼양바이오팜 감마폴리글루탐산으로 구성된 현장 가교 수화겔 및 그의 제조 방법
US9549812B2 (en) * 2012-01-13 2017-01-24 Lifecell Corporation Breast prostheses, methods of manufacturing breast prostheses, and methods of treatment using breast prostheses
US9480747B2 (en) 2012-01-24 2016-11-01 Bvw Holding Ag Class of anti-adhesion hydrogels with healing aspects
US9326773B2 (en) 2012-01-26 2016-05-03 Covidien Lp Surgical device including buttress material
US9010612B2 (en) 2012-01-26 2015-04-21 Covidien Lp Buttress support design for EEA anvil
US9010609B2 (en) 2012-01-26 2015-04-21 Covidien Lp Circular stapler including buttress
BR112014020127A2 (pt) 2012-02-14 2020-06-30 The Regents Of The University Of Calefornia métodos para tratamento, melhoramento ou proteção (prevenção) de um indivíduo ou um paciente, e de uma disfunção, uma doença, uma infecção ou uma condição, e, método para suprimir o ganho de peso, ou suprimir o apepite, ou estimular ou iniciar a perda de peso
WO2013126590A2 (en) 2012-02-21 2013-08-29 Baxter International Inc. Pharmaceutical composition comprising cd34+ cells
US8820606B2 (en) 2012-02-24 2014-09-02 Covidien Lp Buttress retention system for linear endostaplers
EP2822474B1 (de) 2012-03-06 2018-05-02 Ferrosan Medical Devices A/S Druckbehälter mit einer blutstillenden paste
JP6153292B2 (ja) * 2012-05-09 2017-06-28 学校法人 関西大学 化合物連結糖タンパク質
JP6206987B2 (ja) * 2012-05-11 2017-10-04 メディカス バイオサイエンシーズ,エルエルシー 網膜剥離の処置のための生体適合性ヒドロゲル製剤
US9168227B2 (en) 2012-05-31 2015-10-27 Covidien Lp Multi-encapsulated microspheres made with oxidized cellulose for in-situ reactions
US9271937B2 (en) 2012-05-31 2016-03-01 Covidien Lp Oxidized cellulose microspheres
AU2013275758B2 (en) 2012-06-12 2015-03-12 Ferrosan Medical Devices A/S Dry haemostatic composition
US8864892B2 (en) * 2012-06-21 2014-10-21 Empire Technology Development Llc Tailorable lignosulfonate carbonate adhesives
BR112014031707A2 (pt) 2012-06-21 2017-06-27 Lifecell Corp prótese; método para fabricar uma prótese implantável; e método para tratamento
US9499636B2 (en) 2012-06-28 2016-11-22 Covidien Lp Dissolution of oxidized cellulose and particle preparation by cross-linking with multivalent cations
US11253252B2 (en) 2012-07-30 2022-02-22 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US10835241B2 (en) 2012-07-30 2020-11-17 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US10390935B2 (en) 2012-07-30 2019-08-27 Conextions, Inc. Soft tissue to bone repair devices, systems, and methods
US10219804B2 (en) 2012-07-30 2019-03-05 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11944531B2 (en) 2012-07-30 2024-04-02 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11957334B2 (en) 2012-07-30 2024-04-16 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US9427309B2 (en) 2012-07-30 2016-08-30 Conextions, Inc. Soft tissue repair devices, systems, and methods
US9629632B2 (en) 2012-07-30 2017-04-25 Conextions, Inc. Soft tissue repair devices, systems, and methods
JP6433424B2 (ja) 2012-07-31 2018-12-05 バイオアシス テクノロジーズ インコーポレイテッド 脱リン酸化されたリソソーム蓄積症タンパク質およびその使用方法
US20140048580A1 (en) 2012-08-20 2014-02-20 Covidien Lp Buttress attachment features for surgical stapling apparatus
US9395468B2 (en) 2012-08-27 2016-07-19 Ocular Dynamics, Llc Contact lens with a hydrophilic layer
US20140067082A1 (en) 2012-09-06 2014-03-06 Xinyin Liu Bioresorbable ceramic composition for forming a three dimensional scaffold
CA2826786A1 (en) 2012-09-17 2014-03-17 Confluent Surgical, Inc. Multi-encapsulated formulations made with oxidized cellulose
US9161753B2 (en) 2012-10-10 2015-10-20 Covidien Lp Buttress fixation for a circular stapler
US20140131418A1 (en) 2012-11-09 2014-05-15 Covidien Lp Surgical Stapling Apparatus Including Buttress Attachment
AU2013341711A1 (en) 2012-11-12 2015-05-21 Redwood Bioscience, Inc. Compounds and methods for producing a conjugate
JP2016505528A (ja) 2012-11-16 2016-02-25 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア タンパク質の化学修飾のためのピクテ−スペングラーライゲーション
US9310374B2 (en) 2012-11-16 2016-04-12 Redwood Bioscience, Inc. Hydrazinyl-indole compounds and methods for producing a conjugate
US8859705B2 (en) 2012-11-19 2014-10-14 Actamax Surgical Materials Llc Hydrogel tissue adhesive having decreased gelation time and decreased degradation time
DE102012222365A1 (de) 2012-12-05 2014-06-05 Aesculap Ag Zusammensetzung zur Anwendung bei der Prophylaxe von post-chirurgischen Adhäsionen
WO2014095690A1 (en) 2012-12-17 2014-06-26 Novartis Ag Method for making improved uv-absorbing ophthalmic lenses
US9792935B2 (en) * 2012-12-21 2017-10-17 Seagate Technology Llc Magnetic devices with variable overcoats
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
WO2014113540A1 (en) 2013-01-16 2014-07-24 Iowa State University Research Foundation, Inc. A deep intronic target for splicing correction on spinal muscular atrophy gene
US9597426B2 (en) 2013-01-25 2017-03-21 Covidien Lp Hydrogel filled barbed suture
US20140212355A1 (en) 2013-01-28 2014-07-31 Abbott Cardiovascular Systems Inc. Trans-arterial drug delivery
US20140239047A1 (en) 2013-02-28 2014-08-28 Covidien Lp Adherence concepts for non-woven absorbable felt buttresses
EA201591621A1 (ru) 2013-03-04 2015-12-30 ДЕРМЕЛЛ, ЭлЭлСи ди/би/эй ИТЕРНОДЖЕН, ЭлЭлСи Пригодная для инъекции способная к полимеризации in situ коллагеновая композиция
US9782173B2 (en) 2013-03-07 2017-10-10 Covidien Lp Circular stapling device including buttress release mechanism
WO2014160438A1 (en) 2013-03-13 2014-10-02 Bioasis Technologies Inc. Fragments of p97 and uses thereof
US9364199B2 (en) 2013-03-14 2016-06-14 Covidien Lp Medical devices
US10624865B2 (en) 2013-03-14 2020-04-21 Pathak Holdings Llc Methods, compositions, and devices for drug/live cell microarrays
JP6525952B2 (ja) 2013-03-14 2019-06-05 メディカス バイオサイエンシーズ エルエルシー 細胞送達のための生体適合性ヒドロゲルポリマーマトリックス
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
US10328095B2 (en) 2013-03-15 2019-06-25 Covidien Lp Resorbable oxidized cellulose embolization microspheres
US9782430B2 (en) 2013-03-15 2017-10-10 Covidien Lp Resorbable oxidized cellulose embolization solution
JP6603650B2 (ja) 2013-03-15 2019-11-06 パーデュー・リサーチ・ファウンデーション 細胞外マトリックス結合性合成ペプチドグリカン
US10413566B2 (en) 2013-03-15 2019-09-17 Covidien Lp Thixotropic oxidized cellulose solutions and medical applications thereof
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
AU2014283170B2 (en) 2013-06-21 2017-11-02 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US9371423B2 (en) 2013-07-09 2016-06-21 General Electric Company Methods and apparatus for crosslinking a silicon carbide fiber precursor polymer
WO2015013510A1 (en) 2013-07-25 2015-01-29 Ecole Polytechnique Federale De Lausanne Epfl High aspect ratio nanofibril materials
EP3027659B1 (de) 2013-07-29 2020-12-09 Actamax Surgical Materials LLC Gewebeklebstoff mit niedriger schwellung und dichtungsmittelzusammensetzungen
US20150093399A1 (en) 2013-08-28 2015-04-02 Bioasis Technologies, Inc. Cns-targeted conjugates having modified fc regions and methods of use thereof
US20150197534A1 (en) 2013-09-05 2015-07-16 Sarepta Therapeutics, Inc. Antisense-induced exon2 inclusion in acid alpha-glucosidase
CA2930552C (en) 2013-11-15 2022-12-13 Ocular Dynamics, Llc Contact lens with a hydrophilic layer
WO2015081282A1 (en) 2013-11-27 2015-06-04 Redwood Bioscience, Inc. Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ/エス 押し出し増強因子を含んでいる乾燥組成物
US9708087B2 (en) 2013-12-17 2017-07-18 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
RU2699811C1 (ru) 2014-03-07 2019-09-11 Айконлаб Инк. Многоцелевой имплантат с заданной структурой поверхности для реконструкции мягких тканей
US10588732B2 (en) 2014-03-07 2020-03-17 IconLab USA, Inc. Multipurpose implant with modeled surface structure for soft tissue reconstruction
US11583384B2 (en) 2014-03-12 2023-02-21 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US20170182129A1 (en) 2014-04-03 2017-06-29 The Regents Of The University Of California Systemic delivery of virus vectors encoding urocortin-2 and related genes to treat diabetes-related cardiac dysfunctions and congestive heart failure
US10772931B2 (en) 2014-04-25 2020-09-15 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
US9844378B2 (en) 2014-04-29 2017-12-19 Covidien Lp Surgical stapling apparatus and methods of adhering a surgical buttress thereto
EP3143141B1 (de) 2014-05-16 2019-10-02 Oregon State University Antibakterielle antisense-verbindungen und verfahren
AU2015264449B2 (en) 2014-05-19 2022-05-05 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods
EP3169394A4 (de) 2014-05-23 2018-04-25 Viaderm, LLC Vakuumgestützte perkutane anwendung
US10052400B2 (en) 2014-05-30 2018-08-21 Sofradim Production Method for preparing neutralized matrix of non-antigenic collagenous material
WO2016015007A1 (en) 2014-07-25 2016-01-28 Recellerate, Inc. Methods of treating exercise-induced pulmonary hemorrhage
CN106715101B (zh) 2014-08-26 2019-11-05 诺华股份有限公司 用于在硅酮水凝胶接触镜片上施用稳定的涂层的方法
CN105412975B (zh) 2014-09-18 2019-05-31 苏州安德佳生物科技有限公司 一种生物相容性止血制品及其制备方法
EP3000489B1 (de) 2014-09-24 2017-04-05 Sofradim Production Verfahren zur Herstellung einer Antihaft-Sperrschicht
US10449152B2 (en) 2014-09-26 2019-10-22 Covidien Lp Drug loaded microspheres for post-operative chronic pain
BR112017007466B1 (pt) 2014-10-13 2021-03-02 Ferrosan Medical Devices A/S método para preparar uma composição seca, método para reconstituir a composição seca, pasta, composição seca, recipiente, kit homeostático, e, uso de uma composição seca
CN107206119B (zh) 2014-12-09 2021-01-29 实体科学公司 具有生物相容性层的医疗设备涂层
US10653837B2 (en) 2014-12-24 2020-05-19 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
US10835216B2 (en) 2014-12-24 2020-11-17 Covidien Lp Spinneret for manufacture of melt blown nonwoven fabric
CA2972653A1 (en) 2014-12-31 2016-07-07 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods
CN105561405B (zh) * 2015-01-07 2019-07-26 北京赛奇科科技有限公司 一种用于输卵管栓塞的医用材料及其制备方法
CN105561404B (zh) * 2015-01-07 2019-07-26 北京赛奇科科技有限公司 一种用于妇产科防粘连的医用材料及其制备方法
US10470767B2 (en) 2015-02-10 2019-11-12 Covidien Lp Surgical stapling instrument having ultrasonic energy delivery
US9999527B2 (en) 2015-02-11 2018-06-19 Abbott Cardiovascular Systems Inc. Scaffolds having radiopaque markers
US11382731B2 (en) 2015-02-27 2022-07-12 Covidien Lp Medical devices with sealing properties
MA41795A (fr) 2015-03-18 2018-01-23 Sarepta Therapeutics Inc Exclusion d'un exon induite par des composés antisens dans la myostatine
US11020578B2 (en) 2015-04-10 2021-06-01 Covidien Lp Surgical stapler with integrated bladder
CA2925606A1 (en) 2015-04-23 2016-10-23 Covidien Lp Resorbable oxidized cellulose embolization solution
US10376536B2 (en) 2015-05-11 2019-08-13 Murdoch University Multiple sclerosis treatment
JP2018515529A (ja) 2015-05-12 2018-06-14 インセプト・リミテッド・ライアビリティ・カンパニーIncept,Llc ハイドロゲルからの薬物送達
WO2016187426A1 (en) 2015-05-19 2016-11-24 Amorphex Therapeutics Llc A device that delivers a sustained low-dose of a myopia-suppressing drug
EP3851531A1 (de) 2015-06-01 2021-07-21 Sarepta Therapeutics, Inc. Antisense-induzierte exonexklusion in typ-vii-kollagen
US9700443B2 (en) 2015-06-12 2017-07-11 Abbott Cardiovascular Systems Inc. Methods for attaching a radiopaque marker to a scaffold
US10918796B2 (en) 2015-07-03 2021-02-16 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
CN106337037A (zh) * 2015-07-08 2017-01-18 中国科学院上海生命科学研究院 一种诱导成纤维细胞直接向神经细胞转化的药物组合物及其用途
AU2016297642A1 (en) 2015-07-22 2018-02-15 Incept, Llc Coated punctal plug
JP2018530560A (ja) 2015-10-09 2018-10-18 サレプタ セラピューティクス, インコーポレイテッド デュシェンヌ型筋ジストロフィーおよび関連障害の処置のための組成物および方法
EP3391101B1 (de) 2015-12-15 2020-07-08 Alcon Inc. Verfahren zum auftragen einer stabilen beschichtung auf silikonhydrogelkontaktlinsen
AU2016379402B2 (en) 2015-12-23 2023-01-12 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods
EP3394261A4 (de) 2015-12-23 2019-11-27 Oregon State University Antibakterielle antisense-verbindungen und verfahren
KR102522059B1 (ko) 2016-04-18 2023-04-14 사렙타 쎄러퓨틱스 인코퍼레이티드 안티센스 올리고머, 및 산성 알파-글루코시다제 유전자와 연관된 질환을 치료하기 위한 이의 사용 방법
WO2017192753A1 (en) 2016-05-03 2017-11-09 Bvw Holding Ag Multiphase gel
US10959731B2 (en) 2016-06-14 2021-03-30 Covidien Lp Buttress attachment for surgical stapling instrument
AU2017204280A1 (en) 2016-08-12 2018-03-01 Covidien Lp Thixotropic oxidized cellulose solutions and medical applications thereof
WO2018039721A1 (en) 2016-08-31 2018-03-08 Commonwealth Scientific And Industrial Research Organisation Polymer coatings
WO2018055433A1 (en) 2016-09-21 2018-03-29 Peter Law Autonomously controllable pull wire injection catheter, robotic system comprising said catheter and method for operating the same
US11696822B2 (en) 2016-09-28 2023-07-11 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11026686B2 (en) 2016-11-08 2021-06-08 Covidien Lp Structure for attaching buttress to anvil and/or cartridge of surgical stapling instrument
US10874768B2 (en) 2017-01-20 2020-12-29 Covidien Lp Drug eluting medical device
EP3577224A4 (de) 2017-02-03 2020-11-25 The University Of Western Australia Neuartige behandlung von neat1-assoziierten erkrankungen
CN108498879B (zh) 2017-02-28 2021-12-28 苏州安德佳生物科技有限公司 黏膜下注射用组合物和试剂组合及其应用
US10925607B2 (en) 2017-02-28 2021-02-23 Covidien Lp Surgical stapling apparatus with staple sheath
US11202848B2 (en) 2017-03-08 2021-12-21 Baxter International Inc. Surgical adhesive able to glue in wet conditions
US10912859B2 (en) 2017-03-08 2021-02-09 Baxter International Inc. Additive able to provide underwater adhesion
US10368868B2 (en) 2017-03-09 2019-08-06 Covidien Lp Structure for attaching buttress material to anvil and cartridge of surgical stapling instrument
US11096610B2 (en) 2017-03-28 2021-08-24 Covidien Lp Surgical implants including sensing fibers
EP3648774A4 (de) 2017-07-07 2021-04-21 Symic IP, LLC Synthetische biokonjugate
US10849625B2 (en) 2017-08-07 2020-12-01 Covidien Lp Surgical buttress retention systems for surgical stapling apparatus
US20200254232A1 (en) 2017-08-16 2020-08-13 Cardiac Assist Holdings Percutaneous appliance with transdermal collapsible flanges
US10945733B2 (en) 2017-08-23 2021-03-16 Covidien Lp Surgical buttress reload and tip attachment assemblies for surgical stapling apparatus
US11847932B2 (en) 2017-09-07 2023-12-19 Intuitive Surgical Operations, Inc. Modified animal organs for use in surgical simulators
CN111065344B (zh) * 2017-09-08 2023-09-22 三养控股公司 密封剂注射器总成
WO2019079637A2 (en) 2017-10-18 2019-04-25 Sarepta Therapeutics, Inc. ANTISENSE OLIGOMERIC COMPOUNDS
US11141151B2 (en) 2017-12-08 2021-10-12 Covidien Lp Surgical buttress for circular stapling
CN111386478B (zh) 2017-12-13 2023-11-14 爱尔康公司 周抛和月抛水梯度接触镜片
US11547397B2 (en) 2017-12-20 2023-01-10 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
CN111094462A (zh) 2017-12-26 2020-05-01 贝克顿·迪金森公司 深紫外线可激发的水溶剂化聚合物染料
WO2019164853A1 (en) 2018-02-20 2019-08-29 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11065000B2 (en) 2018-02-22 2021-07-20 Covidien Lp Surgical buttresses for surgical stapling apparatus
US10980913B2 (en) 2018-03-05 2021-04-20 Ethicon Llc Sealant foam compositions for lung applications
JP2021519841A (ja) 2018-03-30 2021-08-12 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company ペンダントクロモフォアを有する水溶性ポリマー色素
US10758237B2 (en) 2018-04-30 2020-09-01 Covidien Lp Circular stapling apparatus with pinned buttress
AU2019266529A1 (en) 2018-05-09 2020-12-03 Ethicon Inc. Method for preparing a haemostatic composition
US11426163B2 (en) 2018-05-09 2022-08-30 Covidien Lp Universal linear surgical stapling buttress
US11432818B2 (en) 2018-05-09 2022-09-06 Covidien Lp Surgical buttress assemblies
US11284896B2 (en) 2018-05-09 2022-03-29 Covidien Lp Surgical buttress loading and attaching/detaching assemblies
US11219460B2 (en) 2018-07-02 2022-01-11 Covidien Lp Surgical stapling apparatus with anvil buttress
EP3813867A1 (de) 2018-07-22 2021-05-05 Bioasis Technologies Inc. Behandlung von lymphatischen metastasen
CN112957518B (zh) * 2018-08-20 2022-10-25 稳得希林(杭州)生物科技有限公司 多糖基组织粘合医用胶及其应用
US10806459B2 (en) 2018-09-14 2020-10-20 Covidien Lp Drug patterned reinforcement material for circular anastomosis
US10952729B2 (en) 2018-10-03 2021-03-23 Covidien Lp Universal linear buttress retention/release assemblies and methods
US10517988B1 (en) 2018-11-19 2019-12-31 Endomedix, Inc. Methods and compositions for achieving hemostasis and stable blood clot formation
US11730472B2 (en) 2019-04-25 2023-08-22 Covidien Lp Surgical system and surgical loading units thereof
WO2020227095A1 (en) 2019-05-03 2020-11-12 Lifecell Corporation Breast treatment device
US11478245B2 (en) 2019-05-08 2022-10-25 Covidien Lp Surgical stapling device
US11596403B2 (en) 2019-05-08 2023-03-07 Covidien Lp Surgical stapling device
SG11202112144RA (en) 2019-05-14 2021-11-29 Univ Monash Modulators and modulation of the receptor for advanced glycation end-products rna
US11571208B2 (en) 2019-10-11 2023-02-07 Covidien Lp Surgical buttress loading units
US11523824B2 (en) 2019-12-12 2022-12-13 Covidien Lp Anvil buttress loading for a surgical stapling apparatus
US11964075B2 (en) 2020-01-17 2024-04-23 University Of Florida Research Foundation, Incorporated Injectable composite inks and methods for making and using thereof
US11547407B2 (en) 2020-03-19 2023-01-10 Covidien Lp Staple line reinforcement for surgical stapling apparatus
EP4129353A1 (de) 2020-03-25 2023-02-08 Fukuoka University Mittel zur verwendung in der intraokularen membranablösungschirurgie
US11337699B2 (en) 2020-04-28 2022-05-24 Covidien Lp Magnesium infused surgical buttress for surgical stapler
US20210355468A1 (en) 2020-05-18 2021-11-18 Bioasis Technologies, Inc. Compositions and methods for treating lewy body dementia
US11826028B2 (en) * 2020-06-10 2023-11-28 Ethicon, Inc. Two component sealing systems including synthetic matrices and biosynthetic adhesives for sealing resected surfaces of organs to control bleeding, fluid leaks and air leaks
US20210393787A1 (en) 2020-06-17 2021-12-23 Bioasis Technologies, Inc. Compositions and methods for treating frontotemporal dementia
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
CN111840631A (zh) * 2020-07-23 2020-10-30 青岛大学附属医院 可注射型抗菌止血水凝胶粘合剂及其制备方法和应用
US11707276B2 (en) 2020-09-08 2023-07-25 Covidien Lp Surgical buttress assemblies and techniques for surgical stapling
US11399833B2 (en) 2020-10-19 2022-08-02 Covidien Lp Anvil buttress attachment for surgical stapling apparatus
US11534170B2 (en) 2021-01-04 2022-12-27 Covidien Lp Anvil buttress attachment for surgical stapling apparatus
JP7454880B2 (ja) * 2021-03-22 2024-03-25 ソンバイオ・インコーポレイテッド ポリエチレングリコール誘導体を有効成分として含む口腔乾燥症緩和用口腔リンス組成物
US11510670B1 (en) 2021-06-23 2022-11-29 Covidien Lp Buttress attachment for surgical stapling apparatus
US11596399B2 (en) 2021-06-23 2023-03-07 Covidien Lp Anvil buttress attachment for surgical stapling apparatus
US11672538B2 (en) 2021-06-24 2023-06-13 Covidien Lp Surgical stapling device including a buttress retention assembly
US11678879B2 (en) 2021-07-01 2023-06-20 Covidien Lp Buttress attachment for surgical stapling apparatus
US11684368B2 (en) 2021-07-14 2023-06-27 Covidien Lp Surgical stapling device including a buttress retention assembly
US11801052B2 (en) 2021-08-30 2023-10-31 Covidien Lp Assemblies for surgical stapling instruments
EP4155349A1 (de) 2021-09-24 2023-03-29 Becton, Dickinson and Company Wasserlösliche gelbe grünabsorbierende farbstoffe
CA3233242A1 (en) 2021-09-30 2023-04-06 Sarepta Therapeutics, Inc. Antisense oligonucleotides having one or more abasic units
US11751875B2 (en) 2021-10-13 2023-09-12 Coviden Lp Surgical buttress attachment assemblies for surgical stapling apparatus
US11806017B2 (en) 2021-11-23 2023-11-07 Covidien Lp Anvil buttress loading system for surgical stapling apparatus
CN115177779B (zh) * 2022-06-14 2023-12-05 深圳凡旻生物科技有限公司 一种生物胶及其制备方法与应用
WO2024007016A2 (en) 2022-07-01 2024-01-04 Beckman Coulter, Inc. Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
WO2024044327A1 (en) 2022-08-26 2024-02-29 Beckman Coulter, Inc. Dhnt monomers and polymer dyes with modified photophysical properties

Family Cites Families (187)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB697334A (en) 1950-04-29 1953-09-23 Wingfoot Corp Preparation of polyesters, polyamides or polyesteramides of high molecular weight
NL83472C (de) * 1950-10-30
NL126192C (de) 1964-07-16
US3619371A (en) * 1967-07-03 1971-11-09 Nat Res Dev Production of a polymeric matrix having a biologically active substance bound thereto
SE343210B (de) * 1967-12-20 1972-03-06 Pharmacia Ab
US4008341A (en) 1968-10-11 1977-02-15 W. R. Grace & Co. Curable liquid polymer compositions
US3742955A (en) * 1970-09-29 1973-07-03 Fmc Corp Fibrous collagen derived product having hemostatic and wound binding properties
US3810473A (en) * 1972-12-04 1974-05-14 Avicon Inc Liquid-laid, non-woven, fibrous collagen derived surgical web having hemostatic and wound sealing properties
US3876501A (en) * 1973-05-17 1975-04-08 Baxter Laboratories Inc Binding enzymes to activated water-soluble carbohydrates
GB1479268A (en) * 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
DE2360794C2 (de) * 1973-12-06 1984-12-06 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung von Peptiden
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
CH596313A5 (de) * 1975-05-30 1978-03-15 Battelle Memorial Institute
US4237229A (en) 1975-06-10 1980-12-02 W. R. Grace & Co. Immobilization of biological material with polyurethane polymers
IL47468A (en) * 1975-06-12 1979-05-31 Rehovot Res Prod Process for the cross-linking of proteins using water soluble cross-linking agents
US4488911A (en) * 1975-10-22 1984-12-18 Luck Edward E Non-antigenic collagen and articles of manufacture
US4002531A (en) * 1976-01-22 1977-01-11 Pierce Chemical Company Modifying enzymes with polyethylene glycol and product produced thereby
AT352867B (de) * 1976-05-12 1979-10-10 Battelle Institut E V Knochenersatz-knochenverbund-oder prothesen- verankerungswerkstoff und verfahren zu seiner herstellung
GB1578348A (en) * 1976-08-17 1980-11-05 Pharmacia Ab Products and a method for the therapeutic suppression of reaginic antibodies responsible for common allergic
SE431758B (sv) * 1977-03-04 1984-02-27 Pharmacia Fine Chemicals Ab Som tioleringsreagens eller berarmatris for enzymer anvendbart derivat av en sh-grupphaltig polymer
US4164559A (en) * 1977-09-21 1979-08-14 Cornell Research Foundation, Inc. Collagen drug delivery device
US4238480A (en) * 1978-05-19 1980-12-09 Sawyer Philip Nicholas Method for preparing an improved hemostatic agent and method of employing the same
US4390519A (en) * 1978-05-19 1983-06-28 Sawyer Philip Nicholas Bandage with hemostatic agent and methods for preparing and employing the same
US4404970A (en) * 1978-05-19 1983-09-20 Sawyer Philip Nicholas Hemostatic article and methods for preparing and employing the same
FR2449610A1 (fr) 1979-01-02 1980-09-19 Remy Ets Pierre Procede de bouchage inviolable pour bouteille a goulot a vis
JPS6023084B2 (ja) * 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4279812A (en) * 1979-09-12 1981-07-21 Seton Company Process for preparing macromolecular biologically active collagen
US4412947A (en) * 1979-09-12 1983-11-01 Seton Company Collagen sponge
DE2943520C2 (de) * 1979-10-27 1982-05-19 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von Kollagenschwamm für medizinische oder kosmetische Zwecke
CA1156529A (en) 1980-06-12 1983-11-08 Fred A. Serravallo Fibrous collagenous hemostatic-adhesive webs
CS216992B1 (en) * 1980-07-21 1982-12-31 Miroslav Stol Composite polymere material for the biological and medicinal utilitation and method of preparation thereof
US4314380A (en) * 1980-09-26 1982-02-09 Koken Co., Ltd. Artificial bone
US4415665A (en) * 1980-12-12 1983-11-15 Pharmacia Fine Chemicals Ab Method of covalently binding biologically active organic substances to polymeric substances
US4414147A (en) * 1981-04-17 1983-11-08 Massachusetts Institute Of Technology Methods of decreasing the hydrophobicity of fibroblast and other interferons
JPS57206622A (en) * 1981-06-10 1982-12-18 Ajinomoto Co Inc Blood substitute
GB2108517B (en) * 1981-06-12 1985-06-12 Nat Res Dev Hydrogels
US4451568A (en) * 1981-07-13 1984-05-29 Battelle Memorial Institute Composition for binding bioactive substances
US4357274A (en) * 1981-08-06 1982-11-02 Intermedicat Gmbh Process for the manufacture of sclero protein transplants with increased biological stability
US4415628A (en) * 1981-10-26 1983-11-15 Seton Company Moisture vapor permeable sheet materials
JPS5896026A (ja) * 1981-10-30 1983-06-07 Nippon Chemiphar Co Ltd 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤
US4424208A (en) * 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4578067A (en) * 1982-04-12 1986-03-25 Alcon (Puerto Rico) Inc. Hemostatic-adhesive, collagen dressing for severed biological surfaces
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
US4461298A (en) 1982-07-26 1984-07-24 Ethicon, Inc. Composite sutures of silk and hydrophobic thermoplastic elastomers
US4544516A (en) * 1982-07-28 1985-10-01 Battelle Development Corporation Collagen orientation
US4737544A (en) * 1982-08-12 1988-04-12 Biospecific Technologies, Inc. Biospecific polymers
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
JPS6028936A (ja) * 1983-07-27 1985-02-14 Koken:Kk アテロコラ−ゲン水溶液およびその製造方法
US4563351A (en) * 1983-08-01 1986-01-07 Forsyth Dental Infirmary For Children Self-gelling therapeutic compositions for topical application
US4515637A (en) * 1983-11-16 1985-05-07 Seton Company Collagen-thrombin compositions
US4496689A (en) * 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
US4745098A (en) 1984-02-24 1988-05-17 The Regents Of The University Of California Compositions and method for improving wound healing
CA1295796C (en) * 1984-03-27 1992-02-18 Conrad Whyne Biodegradable matrix and methods for producing same
AU4041685A (en) 1984-04-02 1985-10-10 National Jewish Hospital And Research Center Collagen matrix
CA1259914A (en) 1984-07-06 1989-09-26 Donald G. Wallace Methods of bone repair using collagen
US4789663A (en) * 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
JPS6145765A (ja) * 1984-08-07 1986-03-05 宇部興産株式会社 血管補綴物及びその製造方法
US4553974A (en) * 1984-08-14 1985-11-19 Mayo Foundation Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor
US4687820A (en) * 1984-08-22 1987-08-18 Cuno Incorporated Modified polypeptide supports
US4557764A (en) * 1984-09-05 1985-12-10 Collagen Corporation Process for preparing malleable collagen and the product thereof
US4563350A (en) * 1984-10-24 1986-01-07 Collagen Corporation Inductive collagen based bone repair preparations
GB8430252D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
US4600533A (en) * 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
US4732863A (en) * 1984-12-31 1988-03-22 University Of New Mexico PEG-modified antibody with reduced affinity for cell surface Fc receptors
US4695602A (en) 1985-02-28 1987-09-22 Lnp Corporation Fiber reinforced thermoplastics containing silicone interpenetrating polymer networks
US4839345A (en) 1985-03-09 1989-06-13 Nippon Oil And Fats Co., Ltd. Hydrated adhesive gel and method for preparing the same
US4642117A (en) * 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
CA1260391A (en) * 1985-03-28 1989-09-26 Karl A. Piez Xenogeneic collagen/mineral preparations in bone repair
DE3521684A1 (de) * 1985-06-18 1986-12-18 Dr. Müller-Lierheim KG, Biologische Laboratorien, 8033 Planegg Verfahren zur beschichtung von polymeren
DE3675588D1 (de) * 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
US4766106A (en) * 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
US4851513A (en) * 1985-09-06 1989-07-25 Minnesota Mining And Manufacturing Company Viscoelastic collagen solution for opthalmic use and method of preparation
EP0250571B1 (de) * 1986-01-06 1991-05-22 The University Of Melbourne Niederschlag von kollagen in taktoidform
US4774227A (en) * 1986-02-14 1988-09-27 Collagen Corporation Collagen compositions for bone repair containing autogeneic marrow
US4983580A (en) * 1986-04-04 1991-01-08 Allergan, Inc. Methods and materials for use in corneal wound healing
CA1294546C (en) 1986-04-23 1992-01-21 John S. Sundsmo Wound healing composition containing collagen
US4745180A (en) * 1986-06-27 1988-05-17 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using heparin fragments
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US4829099A (en) 1987-07-17 1989-05-09 Bioresearch, Inc. Metabolically acceptable polyisocyanate adhesives
US6030958A (en) 1987-09-18 2000-02-29 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5017229A (en) 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US4937270A (en) 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US6174999B1 (en) * 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6235726B1 (en) 1987-09-18 2001-05-22 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5364622A (en) * 1987-12-04 1994-11-15 Dr. Karl Thomae Gmbh Methods for preventing adhesions to organs and parts of organs by application of tissue plasminogen activator and hydroxyethylcellulose hydrogel
US4886866A (en) 1987-12-21 1989-12-12 W. R. Grace & Co.-Conn. Contact lenses based on biocompatible polyurethane and polyurea-urethane hydrated polymers
US4950699A (en) * 1988-01-11 1990-08-21 Genetic Laboratories, Inc. Wound dressing incorporating collagen in adhesive layer
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
US5192316A (en) * 1988-02-16 1993-03-09 Allergan, Inc. Ocular device
US4969912A (en) 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US5024742A (en) * 1988-02-24 1991-06-18 Cedars-Sinai Medical Center Method of crosslinking amino acid containing polymers using photoactivatable chemical crosslinkers
FR2628634B1 (fr) 1988-03-15 1990-07-13 Imedex Patch de chirurgie viscerale
ATE111360T1 (de) 1988-05-02 1994-09-15 Project Hear Chirurgisches klebstoffmaterial.
US5290552A (en) * 1988-05-02 1994-03-01 Matrix Pharmaceutical, Inc./Project Hear Surgical adhesive material
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5167960A (en) * 1988-08-03 1992-12-01 New England Deaconess Hospital Corporation Hirudin-coated biocompatible substance
JPH0270749A (ja) * 1988-09-07 1990-03-09 Nippon Shokubai Kagaku Kogyo Co Ltd 硬化性組成物
US5565519A (en) 1988-11-21 1996-10-15 Collagen Corporation Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
US5614587A (en) 1988-11-21 1997-03-25 Collagen Corporation Collagen-based bioadhesive compositions
US5306500A (en) * 1988-11-21 1994-04-26 Collagen Corporation Method of augmenting tissue with collagen-polymer conjugates
US5475052A (en) 1988-11-21 1995-12-12 Collagen Corporation Collagen-synthetic polymer matrices prepared using a multiple step reaction
US5643464A (en) 1988-11-21 1997-07-01 Collagen Corporation Process for preparing a sterile, dry crosslinking agent
US5527856A (en) * 1988-11-21 1996-06-18 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5936035A (en) 1988-11-21 1999-08-10 Cohesion Technologies, Inc. Biocompatible adhesive compositions
US5264214A (en) * 1988-11-21 1993-11-23 Collagen Corporation Composition for bone repair
US5304595A (en) * 1988-11-21 1994-04-19 Collagen Corporation Collagen-polymer conjugates
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5550187A (en) 1988-11-21 1996-08-27 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
DE3903672C1 (de) 1989-02-08 1990-02-01 Lohmann Gmbh & Co Kg
US5324844A (en) * 1989-04-19 1994-06-28 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
US5141747A (en) * 1989-05-23 1992-08-25 Minnesota Mining And Manufacturing Company Denatured collagen membrane
NZ234718A (en) * 1989-08-11 1992-05-26 Saint Gobain Isover Decomposable glass fibres
JPH0790241B2 (ja) 1989-09-01 1995-10-04 日本鋼管株式会社 条鋼の圧延方法
JPH0832784B2 (ja) * 1990-04-25 1996-03-29 東レチオコール株式会社 ポリサルファイドポリマー、その製造方法、及びその硬化型組成物
AU633152B2 (en) * 1989-10-18 1993-01-21 Toray Thiokol Company Limited Polysulfide polyether, method of producing same, polymer composition and curable composition
JPH03176064A (ja) 1989-12-05 1991-07-31 Hoechst Japan Ltd 創面被覆材
US5104957A (en) 1990-02-28 1992-04-14 Autogenesis Technologies, Inc. Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
US5201764A (en) * 1990-02-28 1993-04-13 Autogenesis Technologies, Inc. Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
US5275838A (en) * 1990-02-28 1994-01-04 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
CA2079452C (en) 1990-04-02 1997-04-15 Donald Carroll Roe A particulate, absorbent, polymeric compositions containing interparticle crosslinked aggregates
US5204110A (en) 1990-05-02 1993-04-20 Ndm Acquisition Corp. High absorbency hydrogel wound dressing
US5219564A (en) * 1990-07-06 1993-06-15 Enzon, Inc. Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
EP0466383A1 (de) 1990-07-09 1992-01-15 BAUSCH & LOMB INCORPORATED Medizinischer Kollagenleim und seine Verwendungen
US5209776A (en) * 1990-07-27 1993-05-11 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
SE466754B (sv) * 1990-09-13 1992-03-30 Berol Nobel Ab Saett att kovalent binda biopolymerer till hydrofila ytor
US5410016A (en) * 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5626863A (en) 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5169754A (en) * 1990-10-31 1992-12-08 Coulter Corporation Biodegradable particle coatings having a protein covalently immobilized by means of a crosslinking agent and processes for making same
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
US5219895A (en) * 1991-01-29 1993-06-15 Autogenesis Technologies, Inc. Collagen-based adhesives and sealants and methods of preparation and use thereof
US5156613A (en) * 1991-02-13 1992-10-20 Interface Biomedical Laboratories Corp. Collagen welding rod material for use in tissue welding
AU3124793A (en) 1991-10-29 1993-06-07 Clover Consolidated, Limited Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
WO1993010163A2 (en) 1991-11-12 1993-05-27 Nepera, Inc. Adhesive hydrogels having extended use lives and process for the preparation of same
US5147374A (en) 1991-12-05 1992-09-15 Alfredo Fernandez Prosthetic mesh patch for hernia repair
US5176692A (en) 1991-12-09 1993-01-05 Wilk Peter J Method and surgical instrument for repairing hernia
FR2692582B1 (fr) 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
WO1994001483A1 (en) * 1992-07-02 1994-01-20 Collagen Corporation Biocompatible polymer conjugates
US5428022A (en) * 1992-07-29 1995-06-27 Collagen Corporation Composition of low type III content human placental collagen
US5514379A (en) 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
US5614549A (en) 1992-08-21 1997-03-25 Enzon, Inc. High molecular weight polymer-based prodrugs
AU675252B2 (en) 1992-12-18 1997-01-30 Tremco, Inc. Fast-curing, high strength, two-part sealants using acetoacetate-amine cure chemistry
US5298643A (en) * 1992-12-22 1994-03-29 Enzon, Inc. Aryl imidate activated polyalkylene oxides
US5349001A (en) * 1993-01-19 1994-09-20 Enzon, Inc. Cyclic imide thione activated polyalkylene oxides
US5667839A (en) 1993-01-28 1997-09-16 Collagen Corporation Human recombinant collagen in the milk of transgenic animals
US5321095A (en) * 1993-02-02 1994-06-14 Enzon, Inc. Azlactone activated polyalkylene oxides
WO1994025503A1 (en) * 1993-04-27 1994-11-10 Cytotherapeutics, Inc. Membrane formed by an acrylonitrile-based polymer
US5549904A (en) 1993-06-03 1996-08-27 Orthogene, Inc. Biological adhesive composition and method of promoting adhesion between tissue surfaces
FR2707878A1 (fr) 1993-07-21 1995-01-27 Imedex Nouvelles compositions adhésives à usage chirurgical.
FR2707992B1 (fr) * 1993-07-21 1995-10-13 Flamel Tech Sa Nouveaux produits organiques contenant des fonctions thiols réactives, l'un de leurs procédés de préparation et les biomatériaux les contenant.
US5939385A (en) 1993-08-13 1999-08-17 Zymogenetics, Inc. Transglutaminase cross-linkable polypeptides and methods relating thereto
CA2130295A1 (en) * 1993-08-26 1995-02-27 Richard A. Berg Ionically crosslinked glycosaminoglycan gels for soft tissue augmentation and drug delivery
WO1995007719A1 (fr) 1993-09-16 1995-03-23 Sunao Kubota Materiau pour pansement et composition de pansement
US5605976A (en) 1995-05-15 1997-02-25 Enzon, Inc. Method of preparing polyalkylene oxide carboxylic acids
US5643575A (en) 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
EP0705298B1 (de) * 1993-12-01 2002-03-27 Bioartificial Gel Technologies Inc. Hydrogel auf basis von albumin
US5578661A (en) 1994-03-31 1996-11-26 Nepera, Inc. Gel forming system for use as wound dressings
US5505952A (en) * 1994-04-19 1996-04-09 United States Surgical Corporation Modified synthetic cross-linked amino acid polymers and medical devices formed therefrom
US5583114A (en) * 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
FR2726571B1 (fr) 1994-11-03 1997-08-08 Izoret Georges Colle biologique, procede de preparation et dispositif d'application pour colle biologique, et durcisseurs pour colle biologique
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
CA2167455A1 (en) 1995-01-19 1996-07-20 Kevin Cooper Absorbable polyalkylene diglycolates
US5550172A (en) 1995-02-07 1996-08-27 Ethicon, Inc. Utilization of biocompatible adhesive/sealant materials for securing surgical devices
US5464929A (en) 1995-03-06 1995-11-07 Ethicon, Inc. Absorbable polyoxaesters
US5580923A (en) 1995-03-14 1996-12-03 Collagen Corporation Anti-adhesion films and compositions for medical use
CA2165728A1 (en) 1995-03-14 1996-09-15 Woonza M. Rhee Use of hydrophobic crosslinking agents to prepare crosslinked biomaterial compositions
US5900245A (en) 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
US5612052A (en) * 1995-04-13 1997-03-18 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US5817303A (en) 1995-05-05 1998-10-06 Protein Polymer Technologies, Inc. Bonding together tissue with adhesive containing polyfunctional crosslinking agent and protein polymer
JP4193917B2 (ja) * 1995-12-18 2008-12-10 アンジオデバイス インターナショナル ゲーエムベーハー 架橋ポリマー組成物およびその使用方法
US5752974A (en) 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
US6833408B2 (en) * 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
US6458889B1 (en) 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US5681904A (en) 1996-04-01 1997-10-28 Minnesota Mining And Manufacturing Company Azido polymers having improved burn rate
US6162241A (en) 1997-08-06 2000-12-19 Focal, Inc. Hemostatic tissue sealants
US5854382A (en) 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses
CA2305349A1 (en) 1997-10-27 1999-05-06 Alexander R. Irvine Methods and pharmaceutical compositions for the closure of retinal breaks
WO2000033764A1 (en) 1998-12-04 2000-06-15 Pathak Chandrashekhar P Biocompatible crosslinked polymers
CA2359318C (en) 1999-02-01 2009-06-30 Donald Elbert Biomaterials formed by nucleophilic addition reaction to conjugated unsaturated groups
US6312725B1 (en) * 1999-04-16 2001-11-06 Cohesion Technologies, Inc. Rapid gelling biocompatible polymer composition
US6258124B1 (en) 1999-05-10 2001-07-10 C. R. Bard, Inc. Prosthetic repair fabric
JP2003508564A (ja) 1999-08-27 2003-03-04 コヒージョン テクノロジーズ, インコーポレイテッド 高強度の医療用シーラントとして使用するための相互侵入ポリマー網目構造を形成する組成物
JP4227265B2 (ja) 1999-10-18 2009-02-18 キヤノン株式会社 レーザー光量制御装置
US6296607B1 (en) 2000-10-20 2001-10-02 Praxis, Llc. In situ bulking device

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US5874500A (en) 1999-02-23
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