DE69718148D1 - Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz - Google Patents

Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz

Info

Publication number
DE69718148D1
DE69718148D1 DE69718148T DE69718148T DE69718148D1 DE 69718148 D1 DE69718148 D1 DE 69718148D1 DE 69718148 T DE69718148 T DE 69718148T DE 69718148 T DE69718148 T DE 69718148T DE 69718148 D1 DE69718148 D1 DE 69718148D1
Authority
DE
Germany
Prior art keywords
outlet tube
enriched fraction
centrifuge
enriched
fraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69718148T
Other languages
English (en)
Other versions
DE69718148T2 (de
Inventor
Peter Unger
Eric Westberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Gambro Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Inc filed Critical Gambro Inc
Publication of DE69718148D1 publication Critical patent/DE69718148D1/de
Application granted granted Critical
Publication of DE69718148T2 publication Critical patent/DE69718148T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3698—Expressing processed fluid out from the turning rotor using another fluid compressing the treatment chamber; Variable volume rotors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0427—Platelets; Thrombocytes
DE69718148T 1996-02-26 1997-02-17 Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz Expired - Fee Related DE69718148T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9600713A SE9600713L (sv) 1996-02-26 1996-02-26 Metod för separering av celler, speciellt blodplättar och pås-set därför
PCT/SE1997/000257 WO1997030715A1 (en) 1996-02-26 1997-02-17 Method for separating cells, especially platelets, and bag assembly therefor

Publications (2)

Publication Number Publication Date
DE69718148D1 true DE69718148D1 (de) 2003-02-06
DE69718148T2 DE69718148T2 (de) 2003-10-02

Family

ID=20401543

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69718148T Expired - Fee Related DE69718148T2 (de) 1996-02-26 1997-02-17 Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz

Country Status (8)

Country Link
US (2) US6315706B1 (de)
EP (1) EP0885007B1 (de)
JP (1) JP4112619B2 (de)
AT (1) ATE230271T1 (de)
AU (1) AU713297B2 (de)
DE (1) DE69718148T2 (de)
SE (1) SE9600713L (de)
WO (1) WO1997030715A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9600713L (sv) 1996-02-26 1997-10-17 Omega Medicinteknik Ab Metod för separering av celler, speciellt blodplättar och pås-set därför
SE9700495D0 (sv) 1997-02-12 1997-02-12 Omega Medicinteknik Ab Metod och rundpåsesystem samt centrifug för behandling av blod
DE19846535C2 (de) * 1998-10-09 2000-12-07 Westfalia Separator Ag Zentrifuge
SE516321C2 (sv) * 1999-05-31 2001-12-17 Gambro Inc Centrifug för behandling av blod och blodkomponenter
SE517032C2 (sv) 1999-10-26 2002-04-02 Gambro Inc Sätt och anordning för behandling av blod och blodkomponenter
JP2004536794A (ja) * 2001-04-09 2004-12-09 メドトロニック、インコーポレイテッド マイクロ遠心機を用いる血液成分の分離方法及びその使用法
US6994790B2 (en) * 2002-02-01 2006-02-07 Gambro, Inc. Whole blood collection and processing method
US7241281B2 (en) 2002-04-08 2007-07-10 Thermogenesis Corporation Blood component separation method and apparatus
US7211191B2 (en) * 2004-09-30 2007-05-01 Thermogenesis Corp. Blood component separation method and apparatus
CA2642653A1 (en) * 2002-04-16 2003-10-30 Gambro Bct, Inc. Blood component processing system, apparatus and method
EP1627651B1 (de) * 2002-08-23 2012-04-18 CaridianBCT, Inc. Verfahren und Gerät zur Trennung von Blutkomponenten
US7347932B2 (en) * 2003-08-25 2008-03-25 Gambro Bct, Inc. Apparatus and method for separating a volume of composite liquid into at least two components
JP4705098B2 (ja) * 2004-06-22 2011-06-22 カリディアンビーシーティー、インコーポレーテッド 複合液体分離のためのバッグアセンブリとその製造方法
ATE452668T1 (de) 2004-12-28 2010-01-15 Caridianbct Inc Apparat und methode zur separation einer menge blut in vier komponenten
US7442178B2 (en) * 2005-03-09 2008-10-28 Jacques Chammas Automated system and method for blood components separation and processing
US7473216B2 (en) * 2005-04-21 2009-01-06 Fresenius Hemocare Deutschland Gmbh Apparatus for separation of a fluid with a separation channel having a mixer component
AU2006262692B2 (en) * 2005-06-22 2010-12-09 Caridianbct, Inc. Apparatus and method for separating discrete volumes of a composite liquid
US20100210441A1 (en) * 2005-06-22 2010-08-19 Caridianbct, Inc. Apparatus And Method For Separating Discrete Volumes Of A Composite Liquid
WO2007024518A2 (en) * 2005-08-22 2007-03-01 Gambro Inc. Apparatus and method for separating a composite liquid into at least two components
WO2007120962A2 (en) * 2006-01-30 2007-10-25 Gambro Bct, Inc. Adjusting ph in a method of separating whole blood
CN101460254B (zh) * 2006-06-07 2011-08-24 科安比司特公司 用于将复合液体分成至少两种成分的设备和方法
CN101511406B (zh) * 2006-09-06 2012-08-22 泰尔茂比司特公司 用来将复合液体分离成至少两种成分的设备和方法
WO2008051847A2 (en) * 2006-10-20 2008-05-02 Caridianbct Biotechnologies, Llc Methods for washing a red blood cell component and for removing prions therefrom
US20080147240A1 (en) * 2006-12-19 2008-06-19 Gambro Bct Inc. Apparatus for separating a composite liquid with process control on a centrifuge rotor
EP2091593B1 (de) * 2006-12-20 2012-09-19 Terumo BCT, Inc. Vorrichtung und Verfahren zum Trennen eines Flüssigkeitsgemischs in mindestens zwei Bestandteile
US20080234622A1 (en) * 2007-03-20 2008-09-25 Gambro Bct Inc. Methods and Systems for Preparing Blood Products
WO2008140561A1 (en) * 2007-05-14 2008-11-20 Caridianbct, Inc. Apparatus and method for separating a composite liquid into at least two components
WO2009134521A1 (en) * 2008-05-02 2009-11-05 Caridianbct, Inc. Centrifuge apparatus and method for selectively reducing forces on a biologic fluid
US8120760B2 (en) * 2008-07-31 2012-02-21 Caridianbct, Inc. Method and apparatus for separating a composite liquid into at least two components and for determining the yield of at least one component
EP2451501B1 (de) * 2009-07-06 2013-05-01 Terumo BCT, Inc. Verfahren und system zur zur automatischen ladung einer waschlösung in einen blutprozessor mit mehreren einheiten
DE102010000752A1 (de) * 2010-01-08 2011-07-14 Andreas Hettich GmbH & Co. KG, 78532 Kassette und Systemteil, das in Zusammenwirkung mit der Kassette in einer Zentrifuge einsetzbar ist
MX341634B (es) 2010-03-18 2016-08-08 Syngen Inc Sistema para purificar ciertas poblaciones celulares en sangre o medula osea por agotamiento.
WO2011149614A1 (en) 2010-05-27 2011-12-01 Caridianbct, Inc. Multi-unit blood processor with temperature sensing
WO2011156068A1 (en) 2010-06-07 2011-12-15 Caridianbct, Inc. Multi-unit blood processor with volume prediction
JP5876047B2 (ja) * 2010-07-19 2016-03-02 テルモ ビーシーティー、インコーポレーテッド 血液及び血液成分を処理するための遠心分離器
US9733805B2 (en) 2012-06-26 2017-08-15 Terumo Bct, Inc. Generating procedures for entering data prior to separating a liquid into components
US9804070B2 (en) 2013-03-26 2017-10-31 Alliance Partners, Llc Biological fluids concentration assembly
US10004841B2 (en) 2013-12-09 2018-06-26 Michael C. Larson Blood purifier device and method
CN106572650B (zh) 2014-06-10 2021-08-31 生物马特里卡公司 在环境温度下稳定凝血细胞
SG11201802159UA (en) * 2015-10-14 2018-04-27 Megakaryon Corp Method for producing purified platelets
EP3295973B1 (de) * 2016-09-16 2020-08-26 Fenwal, Inc. Systeme und verfahren zur ableitung und zum sammeln von thrombozytenprodukten
IT201900015707A1 (it) * 2019-09-05 2021-03-05 Emotec Srl "dispositivo medico ed apparato per la produzione, a circuito chiuso, di plasma ricco di piastrine e derivati, ad uso non trasfusionale"

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326458A (en) * 1965-05-28 1967-06-20 Harold T Meryman Container and process of storing blood
US3489145A (en) * 1966-08-08 1970-01-13 Surgeon General Of The Public Method and apparatus for continuous separation of blood in vivo
US3519201A (en) * 1968-05-07 1970-07-07 Us Health Education & Welfare Seal means for blood separator and the like
SE332906B (de) * 1969-08-11 1971-02-22 Aga Ab
JPS50107565A (de) * 1974-01-29 1975-08-25
US4010894A (en) * 1975-11-21 1977-03-08 International Business Machines Corporation Centrifuge fluid container
US4419089A (en) * 1977-07-19 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Blood cell separator
US4387848A (en) * 1977-10-03 1983-06-14 International Business Machines Corporation Centrifuge assembly
US4386730A (en) * 1978-07-21 1983-06-07 International Business Machines Corporation Centrifuge assembly
SE412528B (sv) * 1978-07-25 1980-03-10 Separex Sa Centrifugrotor och kollaberbar separationsbehallare
JPS59500340A (ja) 1982-03-08 1984-03-01 モトロ−ラ・インコ−ポレ−テツド 集積回路のリ−ドフレ−ム
US4530691A (en) * 1983-12-13 1985-07-23 Baxter Travenol Laboratories, Inc. Centrifuge with movable mandrel
WO1987006844A1 (en) 1986-05-16 1987-11-19 Omega Medicinteknik Ab Method and apparatus for plasmapheresis
SE459791B (sv) * 1986-05-16 1989-08-07 Omega Medicinteknik Ab Ringcentrifug
SE454413B (sv) * 1986-09-12 1988-05-02 Alfa Laval Separation Ab Centrifugalseparator med en rotor, vari ett bojligt organ strecker sig ett stycke lengs rotorns omkrets
SE458342B (sv) 1987-07-06 1989-03-20 Alfa Laval Ab Centrifugalseparator innefattande en rotor med en separeringskammare bestaaende av tvaa avdelningar
SE462015B (sv) 1987-09-15 1990-04-30 Omega Medicinteknik Ab Saett och anordning foer tvaettning av blodceller
DE3815645A1 (de) * 1988-05-07 1989-11-16 Biotest Pharma Gmbh Verfahren zur herstellung eines reinen thrombozytenkonzentrates aus gesamtblut
US5116308A (en) * 1989-01-13 1992-05-26 Terumo Kabushiki Kaisha Apparatus for processing fluid and method of driving the same
US5209800A (en) * 1990-08-20 1993-05-11 Denco, Inc. Total containment welding of plastic tubes
SE9302369D0 (sv) * 1993-07-08 1993-07-08 Omega Medicinteknik Ab Paassystem avsett foer centrifugalseparationsamt an vaendning av detta paassystem
US5674173A (en) * 1995-04-18 1997-10-07 Cobe Laboratories, Inc. Apparatus for separating particles
SE9600713L (sv) 1996-02-26 1997-10-17 Omega Medicinteknik Ab Metod för separering av celler, speciellt blodplättar och pås-set därför
SE9700495D0 (sv) * 1997-02-12 1997-02-12 Omega Medicinteknik Ab Metod och rundpåsesystem samt centrifug för behandling av blod
SE9701423D0 (sv) * 1997-04-16 1997-04-16 Omega Medicinteknik Ab Behållarset och anordning för blodseparation

Also Published As

Publication number Publication date
EP0885007A1 (de) 1998-12-23
AU2107997A (en) 1997-09-10
ATE230271T1 (de) 2003-01-15
SE9600713D0 (sv) 1996-02-26
SE9600713L (sv) 1997-10-17
WO1997030715A1 (en) 1997-08-28
EP0885007B1 (de) 2003-01-02
US6315706B1 (en) 2001-11-13
AU713297B2 (en) 1999-11-25
JP4112619B2 (ja) 2008-07-02
US6855102B2 (en) 2005-02-15
DE69718148T2 (de) 2003-10-02
US20020016244A1 (en) 2002-02-07
JP2001517200A (ja) 2001-10-02

Similar Documents

Publication Publication Date Title
DE69718148D1 (de) Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz
Kurnick et al. A rapid method for the separation of functional lymphoid cell populations of human and animal origin on PVP‐silica (Percoll) density gradients
CA1306985C (en) Separation of materials from a liquid dispersion by sedimentation
WO2004030826A3 (en) Buffy coat separator float system and method
EP1391244A3 (de) Verfahren und Vorrichtung zum Trennen von Blutkomponenten
AU4421896A (en) Separator float for blood collection tubes
WO1992007656A3 (en) System and method for processing biological fluids
NO972493D0 (no) Fremgangsmåte og anordning for separering av fibrin fra blodplasma
EP1005909A3 (de) Zentrifugen-Röhrchen mit rundem Trennelement, Verkleidung und Schutzkappe
US4854933A (en) Plasma separator
EP2116609A3 (de) Verfahren zur Isolierung von Zellen und Verwendungen dafür
AU3755200A (en) Platelet collection system
EP1351773A2 (de) Rotorkern für blutbehandlungseinrichtung
AU3671389A (en) Method for separating blood into blood components, and blood components separator unit
BR9806231A (pt) Sistemas e métodos para coletar células mononucleares empregando controle de hematócrito de hemácia agrupada
SE8206767D0 (sv) Sett och anordning for satsvis centrifugalseparering av blod
CA2024892A1 (en) Blood collection method
EP1214982A3 (de) Selbstgetriebene Wegwerfzentrifuge
EP0368621A3 (de) Methode zur Abtrennung lebender Zellen
ES2032846T3 (es) Papel a base de fibras de vidrio.
EP1075844A3 (de) Vorrichtung und Verfahren zur autologenen Transfusion von Blut
ES8405622A1 (es) Sistema colector de componentes sanguineos.
EP0199470A3 (de) Verfahren und Vorrichtung zur Trennung von komplexen Gemischen von bioorganischen Stoffen
EP0882465A3 (de) Methode und Gerät zur Gewinnung einer Plättchensuspension mit reduziertem Leukozytenanteil
CN101306404B (zh) 血液成分制备装置及制备方法

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GAMBRO BCT, INC., LAKEWOOD, COL., US

8327 Change in the person/name/address of the patent owner

Owner name: CARIDIANBCT, INC., LAKEWOOD, COL., US

8339 Ceased/non-payment of the annual fee