DE69718438T2 - Verfahren und vorrichtung zur maldi analyse - Google Patents

Verfahren und vorrichtung zur maldi analyse

Info

Publication number
DE69718438T2
DE69718438T2 DE69718438T DE69718438T DE69718438T2 DE 69718438 T2 DE69718438 T2 DE 69718438T2 DE 69718438 T DE69718438 T DE 69718438T DE 69718438 T DE69718438 T DE 69718438T DE 69718438 T2 DE69718438 T2 DE 69718438T2
Authority
DE
Germany
Prior art keywords
analyte
specimen
matrix
compartment
desorbed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69718438T
Other languages
English (en)
Other versions
DE69718438D1 (de
Inventor
Franz Hillenkamp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sequenom Inc
Original Assignee
Sequenom Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sequenom Inc filed Critical Sequenom Inc
Publication of DE69718438D1 publication Critical patent/DE69718438D1/de
Application granted granted Critical
Publication of DE69718438T2 publication Critical patent/DE69718438T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H01J49/0418—Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00387—Applications using probes
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
DE69718438T 1996-09-19 1997-09-19 Verfahren und vorrichtung zur maldi analyse Expired - Lifetime DE69718438T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/710,565 US5777324A (en) 1996-09-19 1996-09-19 Method and apparatus for maldi analysis
PCT/US1997/016115 WO1998012734A1 (en) 1996-09-19 1997-09-19 Method and apparatus for maldi analysis

Publications (2)

Publication Number Publication Date
DE69718438D1 DE69718438D1 (de) 2003-02-20
DE69718438T2 true DE69718438T2 (de) 2003-10-23

Family

ID=24854565

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69718438T Expired - Lifetime DE69718438T2 (de) 1996-09-19 1997-09-19 Verfahren und vorrichtung zur maldi analyse

Country Status (8)

Country Link
US (4) US5777324A (de)
EP (2) EP0868740B1 (de)
JP (1) JP3601834B2 (de)
AT (1) ATE231284T1 (de)
AU (1) AU724884B2 (de)
CA (1) CA2237946C (de)
DE (1) DE69718438T2 (de)
WO (1) WO1998012734A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102021105327B3 (de) 2021-03-05 2022-05-12 Bruker Daltonics GmbH & Co. KG Desorptions-Ionenquelle mit Postdesorptions-Ionisierung in Transmissionsgeometrie

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