DE69722391D1 - Gärungs-steuerungssysteme - Google Patents

Gärungs-steuerungssysteme

Info

Publication number
DE69722391D1
DE69722391D1 DE69722391T DE69722391T DE69722391D1 DE 69722391 D1 DE69722391 D1 DE 69722391D1 DE 69722391 T DE69722391 T DE 69722391T DE 69722391 T DE69722391 T DE 69722391T DE 69722391 D1 DE69722391 D1 DE 69722391D1
Authority
DE
Germany
Prior art keywords
pct
microorganism
metabolite
date sep
control systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69722391T
Other languages
English (en)
Other versions
DE69722391T2 (de
Inventor
John Mead
Urk Hendrik Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes Biopharma DK AS
Original Assignee
Delta Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605255.0A external-priority patent/GB9605255D0/en
Priority claimed from GBGB9700027.7A external-priority patent/GB9700027D0/en
Application filed by Delta Biotechnology Ltd filed Critical Delta Biotechnology Ltd
Publication of DE69722391D1 publication Critical patent/DE69722391D1/de
Application granted granted Critical
Publication of DE69722391T2 publication Critical patent/DE69722391T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
DE69722391T 1996-03-13 1997-03-12 Gärungs-steuerungssysteme Expired - Lifetime DE69722391T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9605255.0A GB9605255D0 (en) 1996-03-13 1996-03-13 Fermentation control
GB9605255 1996-03-13
GB9700027 1997-01-02
GBGB9700027.7A GB9700027D0 (en) 1997-01-02 1997-01-02 Fermentation control
PCT/GB1997/000669 WO1997033973A1 (en) 1996-03-13 1997-03-12 Fermentation control

Publications (2)

Publication Number Publication Date
DE69722391D1 true DE69722391D1 (de) 2003-07-03
DE69722391T2 DE69722391T2 (de) 2004-04-22

Family

ID=26308922

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69722391T Expired - Lifetime DE69722391T2 (de) 1996-03-13 1997-03-12 Gärungs-steuerungssysteme

Country Status (12)

Country Link
US (1) US6150133A (de)
EP (1) EP0889949B1 (de)
JP (1) JP4318751B2 (de)
KR (1) KR100447374B1 (de)
AT (1) ATE241695T1 (de)
AU (1) AU702567B2 (de)
CA (1) CA2242323C (de)
DE (1) DE69722391T2 (de)
DK (1) DK0889949T3 (de)
ES (1) ES2200153T3 (de)
PT (1) PT889949E (de)
WO (1) WO1997033973A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US6942962B1 (en) * 1999-03-15 2005-09-13 Benedict George Pacocha Computer monitoring and control of fermentation
US20030118598A1 (en) * 2000-02-08 2003-06-26 Allergan, Inc. Clostridial toxin pharmaceutical compositions
US8632785B2 (en) * 2000-02-08 2014-01-21 Allergan, Inc. Clostridial toxin pharmaceutical composition containing a gelatin fragment
MXPA02007519A (es) * 2000-02-08 2004-10-15 Allergan Inc Composiciones farmaceuticas de toxina botulinica.
US7780967B2 (en) * 2000-02-08 2010-08-24 Allergan, Inc. Reduced toxicity Clostridial toxin pharmaceutical compositions
US20060269575A1 (en) * 2000-02-08 2006-11-30 Allergan, Inc. Botulinum toxin pharmaceutical compositions formulated with recombinant albumin
DE10108211A1 (de) * 2001-02-20 2002-08-22 Aventis Pharma Gmbh Verwendung von Fusionsproteinen, deren N-terminaler Anteil aus einem Hirudinderivat besteht, zur Herstellung rekombinanter Proteine über Sekretion durch Hefen
US7638618B2 (en) 2001-02-20 2009-12-29 Sanofi-Aventis Deutschland Gmbh Nucleic acids encoding a hirudin and pro-insulin as superscretable peptides and for parallel improvement of the exported forms of one or more polypeptides of interest
US20050054051A1 (en) * 2001-04-12 2005-03-10 Human Genome Sciences, Inc. Albumin fusion proteins
US7507413B2 (en) * 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
CN1596268A (zh) * 2001-11-28 2005-03-16 桑多斯有限公司 重组人红细胞生成素的层析纯化
DK1463751T3 (da) 2001-12-21 2013-08-26 Human Genome Sciences Inc Albuminfusionsproteiner.
AU2002364587A1 (en) 2001-12-21 2003-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
DE102004007658B4 (de) * 2004-02-17 2008-12-18 Bioceuticals Arzneimittel Ag Verfahren zur Herstellung von rekombinanten Proteinen in eukaryontischen Wirtszellen
WO2006065272A2 (en) * 2004-05-21 2006-06-22 Idaho Research Foundation, Inc. Methods for altering acetic acid production and enhancing cell death in bacteria
JP5102833B2 (ja) 2006-07-24 2012-12-19 バイオレクシス ファーマシューティカル コーポレーション エキセンディン融合タンパク質
CA2714970C (en) * 2008-02-12 2017-06-20 Bioteq Environmental Technologies Inc. Processes for producing h2s using sulphur-reducing bacteria
DE102008002210A1 (de) 2008-06-04 2009-12-10 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Erythropoietin
CN102057034A (zh) * 2008-06-13 2011-05-11 福斯分析股份公司 生物技术工艺的过程控制
DE102011110638A1 (de) * 2011-08-18 2013-02-21 Olaf Kujawski Anlagenweites Steuerungs- und Regelungsverfahren für Biogasanlagen
SG11201400656SA (en) * 2011-09-16 2014-04-28 Amgen Inc Pre-programmed non-feedback controlled continuous feeding of cell cultures
CN105420417B (zh) * 2015-10-26 2019-04-30 上虞新和成生物化工有限公司 基于在线氧消耗速率和电导率协同控制的辅酶q10发酵生产工艺
CN108431204A (zh) 2015-12-22 2018-08-21 阿尔布梅迪克斯医疗有限公司 改良的表达蛋白质的菌株
WO2018234349A1 (en) 2017-06-20 2018-12-27 Albumedix Ltd IMPROVED STRAINS FOR THE EXPRESSION OF PROTEINS
FR3071612B1 (fr) * 2017-09-22 2021-11-19 Agronomique Inst Nat Rech Procede de controle d’un reacteur de fermentation sombre
KR102441806B1 (ko) * 2020-07-22 2022-09-08 최용석 세포배양액의 이온농도 온라인 모니터링 시스템
CN114350533A (zh) * 2022-01-05 2022-04-15 华东理工大学 提升酿酒酵母对2-pe抗性的适应性进化方法和恒化培养装置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD200894A1 (de) * 1981-11-11 1983-06-22 Konrad Soyez Verfahren zur steuerung der kultivierung von mikroorganismen
GB8516912D0 (en) * 1985-07-04 1985-08-07 Johnson Matthey Plc Detecting growth of micro-organisms
JPS6359838A (ja) * 1986-08-30 1988-03-15 Glyco Kyodo Nyugyo Kk 食品の醗酵管理法
JP2676511B2 (ja) * 1987-03-23 1997-11-17 株式会社日立製作所 酢酸を指標とした培養方法及びその装置
SU1495367A1 (ru) * 1987-06-22 1989-07-23 Всесоюзный Проектно-Конструкторский И Научно-Исследовательский Институт Автоматизации Пищевой Промышленности Научно-Производственного Объединения "Пищепромавтоматика" Способ автоматического управлени процессом производства спиртового уксуса
CA1293217C (en) * 1987-11-09 1991-12-17 Sooyoung Stanford Lee Controlled growth rate fermentation
JP2791418B2 (ja) * 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体
JPH02109973A (ja) * 1988-10-19 1990-04-23 Shimadzu Corp 細胞培養装置
DE3927856A1 (de) * 1989-08-23 1991-02-28 Bat Cigarettenfab Gmbh Verfahren zur prozessfuehrung mindestens eines bioreaktors fuer pflanzliche zellkulturen
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing

Also Published As

Publication number Publication date
DK0889949T3 (da) 2003-09-22
WO1997033973A1 (en) 1997-09-18
AU702567B2 (en) 1999-02-25
CA2242323A1 (en) 1997-09-18
JP2000506387A (ja) 2000-05-30
ATE241695T1 (de) 2003-06-15
ES2200153T3 (es) 2004-03-01
CA2242323C (en) 2002-09-10
US6150133A (en) 2000-11-21
PT889949E (pt) 2003-10-31
KR19990087465A (ko) 1999-12-27
EP0889949A1 (de) 1999-01-13
DE69722391T2 (de) 2004-04-22
KR100447374B1 (ko) 2004-11-03
JP4318751B2 (ja) 2009-08-26
AU2104397A (en) 1997-10-01
EP0889949B1 (de) 2003-05-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVOZYMES DELTA LTD., NOTTINGHAM, GB

8327 Change in the person/name/address of the patent owner

Owner name: NOVOZYMES BIOPHARMA UK LIMITED, NOTTINGHAM, GB

8327 Change in the person/name/address of the patent owner

Owner name: NOVOZYMES BIOPHARMA DK A/S, BAGSVAERD, DK