DE69736239D1 - Magnetisch aktivierte zellsortierung zur herstellung von proteinen - Google Patents
Magnetisch aktivierte zellsortierung zur herstellung von proteinenInfo
- Publication number
- DE69736239D1 DE69736239D1 DE69736239T DE69736239T DE69736239D1 DE 69736239 D1 DE69736239 D1 DE 69736239D1 DE 69736239 T DE69736239 T DE 69736239T DE 69736239 T DE69736239 T DE 69736239T DE 69736239 D1 DE69736239 D1 DE 69736239D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- cells
- virus
- antigen
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2855096P | 1996-10-11 | 1996-10-11 | |
US28550P | 1996-10-11 | ||
US884045 | 1997-06-27 | ||
US08/884,045 US5876925A (en) | 1996-10-11 | 1997-06-27 | Magnetically activated cell sorting for production of proteins |
PCT/US1997/018808 WO1998016541A1 (en) | 1996-10-11 | 1997-10-10 | Magnetically activated cell sorting for production of proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69736239D1 true DE69736239D1 (de) | 2006-08-10 |
DE69736239T2 DE69736239T2 (de) | 2007-05-10 |
Family
ID=26703823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69736239T Expired - Lifetime DE69736239T2 (de) | 1996-10-11 | 1997-10-10 | Magnetisch aktivierte zellsortierung zur herstellung von proteinen |
Country Status (9)
Country | Link |
---|---|
US (1) | US5876925A (de) |
EP (1) | EP0935604B1 (de) |
JP (1) | JP4101298B2 (de) |
AT (1) | ATE331727T1 (de) |
AU (1) | AU722978B2 (de) |
CA (1) | CA2268397C (de) |
DE (1) | DE69736239T2 (de) |
ES (1) | ES2267134T3 (de) |
WO (1) | WO1998016541A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6255455B1 (en) * | 1996-10-11 | 2001-07-03 | The Trustees Of The University Of Pennsylvania | Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof |
DE10129815A1 (de) | 2001-06-24 | 2003-01-09 | Profos Ag | Verfahren zur Aufreinigung von Bakterienzellen und Zellbestandteilen |
CA2469464A1 (en) * | 2001-12-07 | 2003-06-19 | Dyax Corporation | Method and apparatus for washing magnetically responsive particles |
DE60319121T2 (de) * | 2002-09-18 | 2009-02-05 | The Trustees Of The University Of Pennsylvania | Zusammensetzungen, verfahren und kits zum nachweis eines antigens auf einer zelle und in einem biologischen gemisch |
DE102004033811A1 (de) * | 2004-07-12 | 2006-02-02 | Salama, Abdulgabar, Prof. Dr. | Verfahren zum einfachen und schnellen Nachweis von Zellen und Biomolekülen mit Hilfe paramagnetischer Partikel |
WO2006007850A1 (en) * | 2004-07-20 | 2006-01-26 | Symphogen A/S | Anti-rhesus d recombinant polyclonal antibody and methods of manufacture |
US8288109B2 (en) * | 2004-07-20 | 2012-10-16 | Symphogen A/S | Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
WO2007064462A1 (en) | 2005-11-29 | 2007-06-07 | The Trustees Of The University Of Pennsylvania | Phage particle diagnostic reagents |
WO2007128795A2 (en) * | 2006-05-05 | 2007-11-15 | Erysave Ab | Method for separation |
EP2537589A1 (de) | 2011-06-21 | 2012-12-26 | Siemens Aktiengesellschaft | Verfahren zum Trennen eines ersten Stoffes aus einem fließfähigen Primärstoffstrom, Vorrichtung zum Trennen eines ersten Stoffes aus einem fließfähigen Primärstoffstrom und Steuer- und/oder Regeleinrichtung |
ES2920601T3 (es) * | 2013-06-28 | 2022-08-05 | X Body Inc | Descubrimiento de antígenos objetivo, cribados fenotípicos y uso de los mismos para la identificación de epítopos objetivo específicos de células objetivo |
US11591718B2 (en) | 2018-04-27 | 2023-02-28 | Aimed Bio Inc. | Magnetic-based biopanning method through attachment of magnetic bead to cell |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5338689A (en) * | 1987-08-24 | 1994-08-16 | Stiftung Fur Diagnostische Forschung | Method and card for detecting antigens and/or antibodies |
US5663143A (en) * | 1988-09-02 | 1997-09-02 | Dyax Corp. | Engineered human-derived kunitz domains that inhibit human neutrophil elastase |
US5498538A (en) * | 1990-02-15 | 1996-03-12 | The University Of North Carolina At Chapel Hill | Totally synthetic affinity reagents |
DE69233367T2 (de) * | 1991-04-10 | 2005-05-25 | The Scripps Research Institute, La Jolla | Bibliotheken heterodimerer rezeptoren mittels phagemiden |
US5665558A (en) * | 1994-05-17 | 1997-09-09 | Gamma Biologicals, Inc. | Method and apparatus useful for detecting bloodgroup antigens and antibodies |
-
1997
- 1997-06-27 US US08/884,045 patent/US5876925A/en not_active Expired - Lifetime
- 1997-10-10 DE DE69736239T patent/DE69736239T2/de not_active Expired - Lifetime
- 1997-10-10 EP EP97911009A patent/EP0935604B1/de not_active Expired - Lifetime
- 1997-10-10 JP JP51861998A patent/JP4101298B2/ja not_active Expired - Lifetime
- 1997-10-10 ES ES97911009T patent/ES2267134T3/es not_active Expired - Lifetime
- 1997-10-10 AT AT97911009T patent/ATE331727T1/de not_active IP Right Cessation
- 1997-10-10 WO PCT/US1997/018808 patent/WO1998016541A1/en active IP Right Grant
- 1997-10-10 AU AU48247/97A patent/AU722978B2/en not_active Expired
- 1997-10-10 CA CA002268397A patent/CA2268397C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0935604B1 (de) | 2006-06-28 |
JP2002503085A (ja) | 2002-01-29 |
EP0935604A4 (de) | 2004-10-20 |
CA2268397A1 (en) | 1998-04-23 |
DE69736239T2 (de) | 2007-05-10 |
AU4824797A (en) | 1998-05-11 |
ATE331727T1 (de) | 2006-07-15 |
ES2267134T3 (es) | 2007-03-01 |
AU722978B2 (en) | 2000-08-17 |
US5876925A (en) | 1999-03-02 |
EP0935604A1 (de) | 1999-08-18 |
CA2268397C (en) | 2008-02-12 |
JP4101298B2 (ja) | 2008-06-18 |
WO1998016541A1 (en) | 1998-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |