DE69736911D1 - Kontrazeptives Implantat für Männer - Google Patents

Kontrazeptives Implantat für Männer

Info

Publication number
DE69736911D1
DE69736911D1 DE69736911T DE69736911T DE69736911D1 DE 69736911 D1 DE69736911 D1 DE 69736911D1 DE 69736911 T DE69736911 T DE 69736911T DE 69736911 T DE69736911 T DE 69736911T DE 69736911 D1 DE69736911 D1 DE 69736911D1
Authority
DE
Germany
Prior art keywords
men
implant
androgen
vinyl acetate
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69736911T
Other languages
English (en)
Other versions
DE69736911T2 (de
Inventor
I Saleh
J Moo-Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Population Council Inc
Original Assignee
Population Council Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Population Council Inc filed Critical Population Council Inc
Application granted granted Critical
Publication of DE69736911D1 publication Critical patent/DE69736911D1/de
Publication of DE69736911T2 publication Critical patent/DE69736911T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
DE69736911T 1996-02-23 1997-02-21 Kontrazeptives Implantat für Männer Expired - Lifetime DE69736911T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US606063 1996-02-23
US08/606,063 US5733565A (en) 1996-02-23 1996-02-23 Male contraceptive implant

Publications (2)

Publication Number Publication Date
DE69736911D1 true DE69736911D1 (de) 2006-12-14
DE69736911T2 DE69736911T2 (de) 2007-06-14

Family

ID=24426375

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69732176T Expired - Lifetime DE69732176T2 (de) 1996-02-23 1997-02-21 Kontrazeptives implantat für männer
DE69736911T Expired - Lifetime DE69736911T2 (de) 1996-02-23 1997-02-21 Kontrazeptives Implantat für Männer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69732176T Expired - Lifetime DE69732176T2 (de) 1996-02-23 1997-02-21 Kontrazeptives implantat für männer

Country Status (12)

Country Link
US (1) US5733565A (de)
EP (2) EP1488784B1 (de)
JP (1) JP2000505419A (de)
AT (2) ATE286370T1 (de)
AU (1) AU1969697A (de)
BR (1) BR9707637A (de)
CA (1) CA2243274C (de)
DE (2) DE69732176T2 (de)
DK (2) DK0881891T3 (de)
ES (2) ES2274367T3 (de)
PT (2) PT1488784E (de)
WO (1) WO1997030656A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306426B1 (en) 1997-08-11 2001-10-23 Allergan Sales, Inc. Implant device with a retinoid for improved biocompatibility
US6767902B2 (en) 1997-09-17 2004-07-27 The Population Council, Inc. Androgen as a male contraceptive and non-contraceptive androgen replacement
US20020012694A1 (en) * 1997-09-17 2002-01-31 Alfred J. Moo-Young Transdermal administration of ment
US5952319A (en) 1997-11-26 1999-09-14 Research Triangle Institute Androgenic steroid compounds and a method of making and using the same
US6117441A (en) * 1998-07-02 2000-09-12 The Population Council, Inc. Silicone core long term androgen delivery implant
NZ331201A (en) * 1998-07-30 2001-02-23 Bomac Lab Ltd Slow release implants comprising an insoluble polymeric material in the form of a porous network containing vitamin B12 dispersed within
US6117442A (en) * 1998-11-12 2000-09-12 Leiras Oy Drug delivery device, especially for the delivery of androgens
PT2561860T (pt) * 2002-05-31 2018-05-08 Titan Pharmaceuticals Inc Dispositivo polimérico implantável para a libertação prolongada de buprenorfina
FR2842421B1 (fr) * 2002-07-16 2004-10-15 Besins Int Belgique Nouvelles compositions pharmaceutiques a base d'inhibiteurs de la 5-alpha-reductase et leurs utilisations
WO2004016083A1 (ja) * 2002-08-19 2004-02-26 Nagoya Industrial Science Research Institute 球脊髄性筋萎縮症の病態を再現する非ヒト動物、及び球脊髄性筋萎縮症治療剤
ZA200507877B (en) 2003-03-31 2007-01-31 Titan Pharmaceuticals Inc Implantable polymeric device for sustained release of dopamine agonist
JO2492B1 (en) 2003-04-28 2009-10-05 شيرينج ايه جي A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
ZA200509063B (en) * 2003-05-30 2007-03-28 Titan Pharmaceuticals Inc Impiantable polymeric device for sustained release of nalmefene
US20060093639A1 (en) * 2004-10-29 2006-05-04 Starkebaum Warren L Method and device for destroying body tissue
JP2008543863A (ja) * 2005-06-15 2008-12-04 ハイドラ バイオサイエンシズ インコーポレイテッド 精子の運動亢進のモジュレーター及びその利用
LT2547332T (lt) * 2010-03-16 2018-12-10 Titan Pharmaceuticals, Inc. Heterogeninės implantuojamos priemonės, skirtos vaisto pristatymui
DE102010014113A1 (de) * 2010-04-07 2011-10-13 Acino Ag Freisetzungsverfahren für Implantate
EP2476409A1 (de) * 2011-01-14 2012-07-18 Université Catholique De Louvain Implantat mit einem Kern und einer den Kern umschliessenden Röhre
WO2017027376A1 (en) 2015-08-07 2017-02-16 Massachusetts Institute Of Technology Subcutaneous drug delivery device with manual activation and deactivation of drug release
SG11202005949UA (en) 2018-05-24 2020-07-29 Celanese Eva Performance Polymers Corp Implantable device for sustained release of a macromolecular drug compound
EP3801462A4 (de) 2018-05-24 2022-03-16 Celanese EVA Performance Polymers LLC Implantierbare vorrichtung zur verzögerten freisetzung einer makromolekularen wirkstoffverbindung
US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11338119B2 (en) 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11173291B2 (en) * 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4052505A (en) * 1975-05-30 1977-10-04 Alza Corporation Ocular therapeutic system manufactured from copolymer
US4451253A (en) * 1980-12-18 1984-05-29 Harman Sherman M Means and method for administering medicinals
US5028430A (en) * 1987-05-08 1991-07-02 Syntex (U.S.A.) Inc. Delivery systems for the controlled administration of LHRH analogs
DE3879031T2 (de) * 1987-08-08 1993-06-24 Akzo Nv Kontrazeptives implantat.
US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
US5266325A (en) * 1990-09-28 1993-11-30 Hydro Med Science Division Of National Patent Development Corp. Preparation of homogeneous hydrogel copolymers
AU651654B2 (en) * 1992-01-14 1994-07-28 Endo Pharmaceuticals Solutions Inc. Manufacture of water-swellable hydrophilic articles and drug delivery devices
US5660848A (en) * 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device

Also Published As

Publication number Publication date
WO1997030656A1 (en) 1997-08-28
DE69736911T2 (de) 2007-06-14
ATE286370T1 (de) 2005-01-15
DK0881891T3 (da) 2005-05-23
EP1488784B1 (de) 2006-11-02
DK1488784T3 (da) 2007-03-05
PT881891E (pt) 2005-04-29
EP0881891A4 (de) 2000-02-02
CA2243274C (en) 2003-07-22
EP1488784A1 (de) 2004-12-22
ES2236793T3 (es) 2005-07-16
BR9707637A (pt) 1999-07-27
AU1969697A (en) 1997-09-10
ATE344018T1 (de) 2006-11-15
DE69732176T2 (de) 2006-05-11
JP2000505419A (ja) 2000-05-09
DE69732176D1 (de) 2005-02-10
ES2274367T3 (es) 2007-05-16
US5733565A (en) 1998-03-31
PT1488784E (pt) 2006-12-29
EP0881891B1 (de) 2005-01-05
CA2243274A1 (en) 1997-08-28
EP0881891A1 (de) 1998-12-09

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Legal Events

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8364 No opposition during term of opposition