DE69739295D1 - Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor - Google Patents

Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor

Info

Publication number
DE69739295D1
DE69739295D1 DE69739295T DE69739295T DE69739295D1 DE 69739295 D1 DE69739295 D1 DE 69739295D1 DE 69739295 T DE69739295 T DE 69739295T DE 69739295 T DE69739295 T DE 69739295T DE 69739295 D1 DE69739295 D1 DE 69739295D1
Authority
DE
Germany
Prior art keywords
recombinant
soluble
adhesion receptor
alphav beta3
alphav
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739295T
Other languages
English (en)
Inventor
Simon L Goodman
Raj Mehta
Beate Diefenbach
Eilish Cullen
Detlev Guessow
Alex Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of DE69739295D1 publication Critical patent/DE69739295D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70557—Integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
DE69739295T 1996-12-09 1997-11-27 Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor Expired - Lifetime DE69739295D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96119700 1996-12-09

Publications (1)

Publication Number Publication Date
DE69739295D1 true DE69739295D1 (de) 2009-04-23

Family

ID=8223479

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69739295T Expired - Lifetime DE69739295D1 (de) 1996-12-09 1997-11-27 Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor

Country Status (5)

Country Link
US (2) US20020055136A1 (de)
EP (1) EP0846702B1 (de)
JP (1) JP4349662B2 (de)
DE (1) DE69739295D1 (de)
ES (1) ES2321991T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268215B1 (en) * 1998-11-04 2001-07-31 The Research Foundation Of State University Of New York Recombinant keratinocytes
BR9916518A (pt) 1998-12-23 2002-01-29 Searle & Co Método para tratar ou prevenir um distúrbio de neoplasia em um mamìfero em necessidade de tal tratamento ou prevenção, e, combinação compreendendo um inibidor de ciclooxigenase-2 e um ou mais agentes anti-neoplásticos
WO2002008280A2 (en) * 2000-07-26 2002-01-31 The Burnham Institute SCREENING METHODS BASED ON SUPERACTIVATED αVβ3 INTEGRIN

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5212071A (en) * 1988-04-01 1993-05-18 The Johns Hopkins University Nucleic acids encoding a human C3b/C4b receptor (CR1)
US4223002A (en) * 1978-08-28 1980-09-16 Hoffmann-La Roche Inc. Isolation of alpha1 -fetoprotein
US4745051A (en) * 1983-05-27 1988-05-17 The Texas A&M University System Method for producing a recombinant baculovirus expression vector
EP1201757A3 (de) * 1988-12-22 2002-09-11 Genentech, Inc. Verfahren zur Herstellung von wasserlöslichen Polypeptiden
US5298418A (en) * 1991-09-16 1994-03-29 Boyce Thompson Institute For Plant Research, Inc. Cell line isolated from larval midgut tissue of Trichoplusia ni
DE69322860T2 (de) * 1992-04-03 1999-07-01 Genentech Inc Antikörper gegen alpha v beta 3 integrin
US5753230A (en) * 1994-03-18 1998-05-19 The Scripps Research Institute Methods and compositions useful for inhibition of angiogenesis
DE69531187T2 (de) * 1994-12-20 2004-04-22 Merck Patent Gmbh Monoklonaler Antikörper gegen das Alpha-V-Integrin
WO1997008316A1 (en) * 1995-08-31 1997-03-06 Merck & Co., Inc. Mouse integrin subunits
US5854205A (en) * 1995-10-23 1998-12-29 The Children's Medical Center Corporation Therapeutic antiangiogenic compositions and methods

Also Published As

Publication number Publication date
US8067197B2 (en) 2011-11-29
US20020055136A1 (en) 2002-05-09
JPH10174591A (ja) 1998-06-30
EP0846702A3 (de) 2001-07-18
EP0846702B1 (de) 2009-03-11
EP0846702A2 (de) 1998-06-10
JP4349662B2 (ja) 2009-10-21
ES2321991T3 (es) 2009-06-15
US20050130137A1 (en) 2005-06-16

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Legal Events

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