DE69739996D1 - Methoden und Zusammensetzungen zur Herstellung von Polypeptiden - Google Patents

Methoden und Zusammensetzungen zur Herstellung von Polypeptiden

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Publication number
DE69739996D1
DE69739996D1 DE69739996T DE69739996T DE69739996D1 DE 69739996 D1 DE69739996 D1 DE 69739996D1 DE 69739996 T DE69739996 T DE 69739996T DE 69739996 T DE69739996 T DE 69739996T DE 69739996 D1 DE69739996 D1 DE 69739996D1
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Germany
Prior art keywords
methods
compositions
polypeptides
production
evolution
Prior art date
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Expired - Lifetime
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DE69739996T
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English (en)
Inventor
Phillip Andrew Patten
Willem Peter Christiaan Stemmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Codexis Mayflower Holdings LLC
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Maxygen Inc
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Application filed by Maxygen Inc filed Critical Maxygen Inc
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Publication of DE69739996D1 publication Critical patent/DE69739996D1/de
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    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1031—Mutagenizing nucleic acids mutagenesis by gene assembly, e.g. assembly by oligonucleotide extension PCR
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N9/0004—Oxidoreductases (1.)
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    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • C12N2795/00011—Details
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    • C12N2795/14141—Use of virus, viral particle or viral elements as a vector
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    • C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
DE69739996T 1996-12-18 1997-12-17 Methoden und Zusammensetzungen zur Herstellung von Polypeptiden Expired - Lifetime DE69739996D1 (de)

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Application Number Priority Date Filing Date Title
US08/769,062 US6335160B1 (en) 1995-02-17 1996-12-18 Methods and compositions for polypeptide engineering

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DE69739996D1 true DE69739996D1 (de) 2010-10-28

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US (20) US6335160B1 (de)
EP (5) EP1149905B1 (de)
JP (2) JP5008784B2 (de)
KR (1) KR20000069591A (de)
AT (1) ATE481480T1 (de)
AU (1) AU732146B2 (de)
CA (2) CA2274319C (de)
DE (1) DE69739996D1 (de)
DK (2) DK1149905T3 (de)
ES (1) ES2351673T3 (de)
IL (1) IL130190A0 (de)
WO (1) WO1998027230A1 (de)

Families Citing this family (428)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7150982B2 (en) 1991-09-09 2006-12-19 Third Wave Technologies, Inc. RNA detection assays
US6759226B1 (en) 2000-05-24 2004-07-06 Third Wave Technologies, Inc. Enzymes for the detection of specific nucleic acid sequences
US7045289B2 (en) 1991-09-09 2006-05-16 Third Wave Technologies, Inc. Detection of RNA Sequences
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US20060084091A1 (en) 2006-04-20
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CA2589337A1 (en) 1998-06-25
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