DE69825495D1 - Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo - Google Patents
Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivoInfo
- Publication number
- DE69825495D1 DE69825495D1 DE69825495T DE69825495T DE69825495D1 DE 69825495 D1 DE69825495 D1 DE 69825495D1 DE 69825495 T DE69825495 T DE 69825495T DE 69825495 T DE69825495 T DE 69825495T DE 69825495 D1 DE69825495 D1 DE 69825495D1
- Authority
- DE
- Germany
- Prior art keywords
- less
- pores
- formulation
- amount
- case
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP1998/008421 WO2000038653A1 (en) | 1998-12-23 | 1998-12-23 | Improved formulation for topical non-invasive application in vivo |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69825495D1 true DE69825495D1 (de) | 2004-09-09 |
DE69825495T2 DE69825495T2 (de) | 2005-07-28 |
Family
ID=8167168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69825495T Expired - Lifetime DE69825495T2 (de) | 1998-12-23 | 1998-12-23 | Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo |
Country Status (22)
Country | Link |
---|---|
US (2) | US7175850B2 (de) |
EP (1) | EP1140021B1 (de) |
JP (1) | JP2002533379A (de) |
KR (1) | KR100638150B1 (de) |
CN (1) | CN1320880C (de) |
AT (1) | ATE272391T1 (de) |
AU (1) | AU770803B2 (de) |
BR (1) | BR9816113A (de) |
CA (1) | CA2356080C (de) |
CZ (1) | CZ20012038A3 (de) |
DE (1) | DE69825495T2 (de) |
EE (1) | EE200100342A (de) |
ES (1) | ES2226203T3 (de) |
HK (1) | HK1040629B (de) |
HR (1) | HRP20010309B1 (de) |
HU (1) | HUP0104424A3 (de) |
MX (1) | MXPA01006424A (de) |
NO (1) | NO20013164L (de) |
PL (1) | PL193824B1 (de) |
RU (1) | RU2207844C2 (de) |
TR (1) | TR200101790T2 (de) |
WO (1) | WO2000038653A1 (de) |
Families Citing this family (109)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
KR100464601B1 (ko) * | 1998-10-23 | 2004-12-31 | 이데아 악티엔게젤샤프트 | 페이로드를 증가시키고, 분리/결합율을 제어하기 위한 거대 분자 결합체 및 복합응집체의 생장, 시험 및 사용방법 |
JP2002533379A (ja) * | 1998-12-23 | 2002-10-08 | イデア アクチェンゲゼルシャフト | 生体内における局所的に非侵襲性である用途のための改善された製剤 |
DK1031346T3 (da) | 1999-01-27 | 2002-08-12 | Idea Ag | Ikke-invasiv vaccination gennem huden |
SI1031347T1 (en) | 1999-01-27 | 2002-10-31 | Idea Ag | Transnasal transport/immunisation with highly adaptable carriers |
MXPA02000053A (es) * | 1999-07-05 | 2003-07-21 | Idea Ag | Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables. |
US20030077301A1 (en) * | 1999-12-16 | 2003-04-24 | Maibach Howard I. | Topical pharmaceutical composition for the treatment of inflammatory dermatoses |
JP2004504357A (ja) * | 2000-07-26 | 2004-02-12 | アルコン,インコーポレイテッド | ポリマー性懸濁化剤を含有しない薬学的懸濁組成物 |
DE60117858T2 (de) | 2000-12-07 | 2006-11-30 | Universiteit Utrecht Holding B.V. | Zusammensetzung zur behandlung von entzündlichen erkrankungen |
US8246969B2 (en) | 2001-11-16 | 2012-08-21 | Skinmedica, Inc. | Compositions containing aromatic aldehydes and their use in treatments |
US7763663B2 (en) | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
ES2411656T3 (es) * | 2002-03-13 | 2013-07-08 | Thomas SKÖLD | Sistemas de administración a base de agua |
US8367098B2 (en) | 2002-04-30 | 2013-02-05 | The Population Council, Inc. | Unique combinations of antimicrobial compositions |
EP1371362A1 (de) * | 2002-06-12 | 2003-12-17 | Universiteit Utrecht Holding B.V. | Zusammensetzung zur Behandlung entzündlicher Erkrankungen |
IL165910A0 (en) * | 2002-07-03 | 2006-01-15 | Pericor Science Inc | Compositions of hyaluronic acid and methods of use |
US20040105881A1 (en) * | 2002-10-11 | 2004-06-03 | Gregor Cevc | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
ES2298566T3 (es) * | 2002-10-11 | 2008-05-16 | Idea Ag | Agregado con deformabilidad incrementada, que comprende por lo menos tres componentes anfipaticos, para un transporte mejorado a traves de barreras semipermeables y para la aplicacion de farmacos no invasiva in vivo, especialmente a traves de la piel. |
AU2003293500A1 (en) * | 2002-12-12 | 2004-07-09 | Agennix Incorporated | Lactoferrin in the reduction of pain |
WO2004103285A2 (en) * | 2003-05-14 | 2004-12-02 | Agennix Incorporated | Lactoferrin in the treatment of diabetes mellitus |
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KR100772327B1 (ko) * | 2004-04-22 | 2007-10-31 | 주식회사유한양행 | 하이드로코티손 또는 그 염을 함유하는 나노에멀젼 조성물 |
DE102004021992A1 (de) * | 2004-05-03 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Topische Zubereitung enthaltend Ambroxol |
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US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
CN102772396B (zh) * | 2012-07-25 | 2013-12-18 | 杭州普瑞美克生物科技有限公司 | 用于动物抓咬伤后皮肤清洁抗菌且配合使用的组合型制剂 |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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- 1998-12-23 PL PL98349467A patent/PL193824B1/pl not_active IP Right Cessation
- 1998-12-23 RU RU2001120008/14A patent/RU2207844C2/ru not_active IP Right Cessation
- 1998-12-23 EP EP98966846A patent/EP1140021B1/de not_active Revoked
- 1998-12-23 MX MXPA01006424A patent/MXPA01006424A/es not_active IP Right Cessation
- 1998-12-23 CA CA002356080A patent/CA2356080C/en not_active Expired - Fee Related
- 1998-12-23 ES ES98966846T patent/ES2226203T3/es not_active Expired - Lifetime
- 1998-12-23 EE EEP200100342A patent/EE200100342A/xx unknown
- 1998-12-23 AT AT98966846T patent/ATE272391T1/de not_active IP Right Cessation
- 1998-12-23 KR KR1020017006708A patent/KR100638150B1/ko not_active IP Right Cessation
- 1998-12-23 CZ CZ20012038A patent/CZ20012038A3/cs unknown
- 1998-12-23 TR TR2001/01790T patent/TR200101790T2/xx unknown
- 1998-12-23 WO PCT/EP1998/008421 patent/WO2000038653A1/en not_active Application Discontinuation
- 1998-12-23 DE DE69825495T patent/DE69825495T2/de not_active Expired - Lifetime
- 1998-12-23 AU AU25137/99A patent/AU770803B2/en not_active Ceased
- 1998-12-23 CN CNB988143690A patent/CN1320880C/zh not_active Expired - Fee Related
- 1998-12-23 BR BR9816113-0A patent/BR9816113A/pt not_active Application Discontinuation
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- 2001-06-22 US US09/887,493 patent/US7175850B2/en not_active Expired - Fee Related
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2002
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