DE69922489D1 - Rekombinantes aktives humänes zona pellucida protein 3 (hzp3) - Google Patents

Rekombinantes aktives humänes zona pellucida protein 3 (hzp3)

Info

Publication number
DE69922489D1
DE69922489D1 DE69922489T DE69922489T DE69922489D1 DE 69922489 D1 DE69922489 D1 DE 69922489D1 DE 69922489 T DE69922489 T DE 69922489T DE 69922489 T DE69922489 T DE 69922489T DE 69922489 D1 DE69922489 D1 DE 69922489D1
Authority
DE
Germany
Prior art keywords
zona pellucida
humanese
hzp3
human
pellucida protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69922489T
Other languages
English (en)
Other versions
DE69922489T2 (de
Inventor
Ke-Wen Dong
Sergio Oehninger
E Gibbons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eastern Virginia Medical School
Original Assignee
Eastern Virginia Medical School
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastern Virginia Medical School filed Critical Eastern Virginia Medical School
Publication of DE69922489D1 publication Critical patent/DE69922489D1/de
Application granted granted Critical
Publication of DE69922489T2 publication Critical patent/DE69922489T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
DE69922489T 1998-02-19 1999-02-19 Rekombinantes aktives humanes Zona Pellucida Expired - Fee Related DE69922489T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7507998P 1998-02-19 1998-02-19
US75079P 1998-02-19
PCT/US1999/003273 WO1999042581A1 (en) 1998-02-19 1999-02-19 RECOMBINANT ACTIVE HUMAN ZONA PELLUCIDA PROTEIN 3 (hZP3)

Publications (2)

Publication Number Publication Date
DE69922489D1 true DE69922489D1 (de) 2005-01-13
DE69922489T2 DE69922489T2 (de) 2005-12-15

Family

ID=22123416

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69922489T Expired - Fee Related DE69922489T2 (de) 1998-02-19 1999-02-19 Rekombinantes aktives humanes Zona Pellucida

Country Status (13)

Country Link
US (1) US7019114B2 (de)
EP (1) EP1056858B1 (de)
JP (1) JP2002504330A (de)
CN (1) CN1291229A (de)
AT (1) ATE284443T1 (de)
AU (1) AU763247C (de)
BR (1) BR9908096A (de)
CA (1) CA2321196A1 (de)
DE (1) DE69922489T2 (de)
ES (1) ES2234274T3 (de)
HK (1) HK1032608A1 (de)
TW (1) TWI229085B (de)
WO (1) WO1999042581A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE284443T1 (de) 1998-02-19 2004-12-15 Eastern Virginia Med School Rekombinantes aktives humänes zona pellucida protein 3 (hzp3)
US7037663B2 (en) * 1998-02-19 2006-05-02 Eastern Virginia Medical School Human zona pellucida protein 3 and uses thereof
EP1421104A4 (de) * 2001-08-02 2005-08-24 Trinity Biomedical Technology Humane zona-pellucida-proteine und verfahren zu deren verwendung bei der diagnose männlicher unfruchtbarkeit
CN103169949A (zh) * 2005-11-16 2013-06-26 潘塔希生物科学股份有限公司 用于治疗或预防卵巢癌的药物组合物
CA2630175C (en) 2005-11-16 2018-10-23 Pantarhei Bioscience B.V. Immunotherapeutic method for treating and/or preventing ovarian cancer
US20080187549A1 (en) * 2007-02-07 2008-08-07 Morey William A Polyantigenic-based (multiple antigens) modi or set of methods for developing infertility vaccines
BR112013004389A2 (pt) 2010-08-27 2016-05-17 Pantarhei Bioscience Bv método imunoterapêutico para tratamento do câncer de próstata
WO2016080830A2 (en) 2014-11-18 2016-05-26 Pantarhei Bioscience B.V. Immunotherapeutic method for treating pancreatic cancer
KR102594453B1 (ko) 2018-08-24 2023-10-25 스페르모센스 에이비 남성 불임을 위한 바이오센서
CN110170044A (zh) * 2019-06-22 2019-08-27 江西省妇幼保健院 Tat-tdrg1在制备治疗弱精子症药物中的应用

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634665A (en) * 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5179017A (en) * 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4444879A (en) 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US5034322A (en) * 1983-01-17 1991-07-23 Monsanto Company Chimeric genes suitable for expression in plant cells
US5352605A (en) * 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
US4960704A (en) * 1983-07-22 1990-10-02 Eli Lilly And Company Modified antibiotic resistance gene
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
IL71691A (en) * 1984-04-27 1991-04-15 Yeda Res & Dev Production of interferon-ypsilon
EP0176971A3 (de) * 1984-09-29 1987-12-02 Wakamoto Pharmaceutical Co., Ltd. Für ein thermostabiles Beta-Galaktosidase, kodierendes Gen, dieses Gen enthaltender Bacillus-subtilis, das durch dieses Gen kodiertes Enzym und Verfahren zu dessen Herstellung
US4996297A (en) 1987-10-07 1991-02-26 Zonagen, Inc. Recombinantly expressed rabbit zona pellucida polypeptides
US5869053A (en) * 1988-03-04 1999-02-09 Cancer Research Campaign Technology, Ltd. 5T4 antigen from human trophoblasts
US5641487A (en) 1989-06-12 1997-06-24 The Government Of The United States Of America As Represented By The Secretary Department Of Health And Human Services Contraceptive vaccine based on alloimmunization with zona pellucida polypeptides
JPH05500654A (ja) 1989-06-12 1993-02-12 アメリカ合衆国 クローン化透明帯遺伝子を基本とする避妊ワクチン
US5272071A (en) 1989-12-22 1993-12-21 Applied Research Systems Ars Holding N.V. Method for the modification of the expression characteristics of an endogenous gene of a given cell line
HUT64394A (en) * 1990-08-27 1993-12-28 Akzo Nv Protein of human zona pellucida zp3
ATE153695T1 (de) 1990-11-26 1997-06-15 Akzo Nobel Nv Verfahren zur herstellung von antikörpern
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
WO1993014786A1 (en) 1992-02-04 1993-08-05 Colorado State University Research Foundation Composition and method to prevent conception or to cause sterility in animals
US5851763A (en) * 1992-09-17 1998-12-22 Institut Pasteur Rapid detection of antibiotic resistance in mycobacterium tuberculosis
DE69322166T2 (de) * 1992-08-28 1999-04-22 Tufts College Prüfung auf ein vielfache resistenz gegen antibiotika verursachendes operon
US5744345A (en) * 1992-10-05 1998-04-28 Takara Shuzo Co., Ltd. Hyperthermostable β-galactosidase gene, enzyme encoded thereby, and process for production
WO1994010304A1 (en) 1992-11-02 1994-05-11 Akzo Nobel N.V. Marmoset zona pellucida protein zp3
AU675269B2 (en) * 1992-11-09 1997-01-30 Zonagen, Inc. Materials and methods for immunocontraception
US6001599A (en) 1992-11-09 1999-12-14 Zonagen, Inc. DNAs encoding mammalian ZPBs
US5888981A (en) * 1993-06-14 1999-03-30 Basf Aktiengesellschaft Methods for regulating gene expression
CA2165162C (en) * 1993-06-14 2000-05-23 Hermann Bujard Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters
WO1995027206A1 (en) 1994-03-31 1995-10-12 Board Of Regents, The University Of Texas System Mannose in vitro binding assay and uses thereof in sperm evaluation
US5851817A (en) * 1994-07-19 1998-12-22 Board Of Regents, The University Of Texas System Species specific egg-binding proteins of sperm
WO1996005305A1 (en) 1994-08-11 1996-02-22 Duke University Use of zrk peptide sequences in contraception
CN1158623A (zh) 1994-08-22 1997-09-03 阿克佐诺贝尔公司 新的免疫避孕肽
US5710038A (en) * 1994-11-25 1998-01-20 Universite De Montreal Primary cultures of normal and tumoral human ovarian epithelium
US5650321A (en) * 1995-01-27 1997-07-22 Trustees Of Tufts College Identification and isolation of new genes of a bacterial multiple antibiotic resistance regulon
US5703057A (en) * 1995-04-07 1997-12-30 Board Of Regents The University Of Texas System Expression library immunization
US5851796A (en) * 1995-06-07 1998-12-22 Yale University Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes
US5821350A (en) * 1995-11-01 1998-10-13 Nexia Biotechnologies, Inc. Aspergillus niger beta-galactosidase gene
US5891718A (en) * 1996-03-27 1999-04-06 Vical Incorporated Tetracycline inducible/repressible systems
US5925541A (en) * 1996-09-11 1999-07-20 New York Blood Center, Inc. Endo-β-galactosidase
WO1998037185A2 (en) 1997-02-20 1998-08-27 The Board Of Regents Of The University Of Texas System Vectors for controlled gene expression
US6132952A (en) 1997-05-30 2000-10-17 Saint Barnabas Medical Center Storage system comprising an emptied zona pellucida and spermatozoa placed therein and a method of cryopreservation
US5968773A (en) * 1997-11-14 1999-10-19 Heddle; John A. System and method for regulation of gene expression
AU2096199A (en) 1998-01-02 1999-07-26 University Of Georgia Research Foundation, Inc., The Fertility impairing vaccine and method of use
ATE284443T1 (de) 1998-02-19 2004-12-15 Eastern Virginia Med School Rekombinantes aktives humänes zona pellucida protein 3 (hzp3)
US7037663B2 (en) * 1998-02-19 2006-05-02 Eastern Virginia Medical School Human zona pellucida protein 3 and uses thereof
US6300311B1 (en) 1998-04-14 2001-10-09 Texas Tech University Regulation of vertebrate ovarian maturation and function using growth factors
WO1999064626A2 (en) 1998-06-06 1999-12-16 Genostic Pharma Limited Probes used for genetic profiling
WO1999064627A2 (en) 1998-06-06 1999-12-16 Genostic Pharma Limited Probes used for genetic profiling
WO1999065520A1 (en) 1998-06-19 1999-12-23 University Of Virginia Patent Foundation Egg surface proteins and methods for use for modulating fertility
WO1999065928A2 (en) 1998-06-19 1999-12-23 Genzyme Corporation Polynucleotide population isolated from non-metastatic and metastatic breast tumor tissues
EP1421104A4 (de) * 2001-08-02 2005-08-24 Trinity Biomedical Technology Humane zona-pellucida-proteine und verfahren zu deren verwendung bei der diagnose männlicher unfruchtbarkeit

Also Published As

Publication number Publication date
AU763247B2 (en) 2003-07-17
AU763247C (en) 2005-05-19
CA2321196A1 (en) 1999-08-26
WO1999042581A1 (en) 1999-08-26
ATE284443T1 (de) 2004-12-15
BR9908096A (pt) 2000-10-31
HK1032608A1 (en) 2001-07-27
EP1056858A1 (de) 2000-12-06
CN1291229A (zh) 2001-04-11
DE69922489T2 (de) 2005-12-15
ES2234274T3 (es) 2005-06-16
JP2002504330A (ja) 2002-02-12
US20020172982A1 (en) 2002-11-21
AU3294699A (en) 1999-09-06
TWI229085B (en) 2005-03-11
US7019114B2 (en) 2006-03-28
EP1056858B1 (de) 2004-12-08

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