DE69930379D1 - Oligonukleotide mit pyrazolä3,4-dü pyrimidin zur hybridisierung und unterscheidung von fehlpaarungen - Google Patents

Oligonukleotide mit pyrazolä3,4-dü pyrimidin zur hybridisierung und unterscheidung von fehlpaarungen

Info

Publication number
DE69930379D1
DE69930379D1 DE69930379T DE69930379T DE69930379D1 DE 69930379 D1 DE69930379 D1 DE 69930379D1 DE 69930379 T DE69930379 T DE 69930379T DE 69930379 T DE69930379 T DE 69930379T DE 69930379 D1 DE69930379 D1 DE 69930379D1
Authority
DE
Germany
Prior art keywords
oligonucleotides
hybridization
pyrazolo
pyrazolä3
pyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69930379T
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English (en)
Other versions
DE69930379T2 (de
Inventor
B Meyer
A Afonina
V Kutyavin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanogen Inc
Original Assignee
Epoch Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epoch Biosciences Inc filed Critical Epoch Biosciences Inc
Publication of DE69930379D1 publication Critical patent/DE69930379D1/de
Application granted granted Critical
Publication of DE69930379T2 publication Critical patent/DE69930379T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69930379T 1998-04-03 1999-04-05 Oligonukleotide mit pyrazolä3,4-dü pyrimidin zur hybridisierung und unterscheidung von fehlpaarungen Expired - Lifetime DE69930379T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54830 1998-04-03
US09/054,830 US6127121A (en) 1998-04-03 1998-04-03 Oligonucleotides containing pyrazolo[3,4-D]pyrimidines for hybridization and mismatch discrimination
PCT/US1999/007492 WO1999051775A1 (en) 1998-04-03 1999-04-05 Oligonucleotides containing pyrazolo[3,4-d]pyrimidines for hybridization and mismatch discrimination

Publications (2)

Publication Number Publication Date
DE69930379D1 true DE69930379D1 (de) 2006-05-11
DE69930379T2 DE69930379T2 (de) 2006-10-05

Family

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Family Applications (1)

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DE69930379T Expired - Lifetime DE69930379T2 (de) 1998-04-03 1999-04-05 Oligonukleotide mit pyrazolä3,4-dü pyrimidin zur hybridisierung und unterscheidung von fehlpaarungen

Country Status (8)

Country Link
US (4) US6127121A (de)
EP (1) EP1068358B1 (de)
JP (1) JP4558932B2 (de)
AT (1) ATE320508T1 (de)
AU (1) AU759944B2 (de)
CA (1) CA2327547C (de)
DE (1) DE69930379T2 (de)
WO (1) WO1999051775A1 (de)

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AU3472499A (en) 1999-10-25
CA2327547A1 (en) 1999-10-14
JP4558932B2 (ja) 2010-10-06
US6485906B2 (en) 2002-11-26
WO1999051775A1 (en) 1999-10-14
AU759944B2 (en) 2003-05-01
EP1068358B1 (de) 2006-03-15
DE69930379T2 (de) 2006-10-05
US6127121A (en) 2000-10-03
JP2002510507A (ja) 2002-04-09
US20020146690A1 (en) 2002-10-10
US20030143602A1 (en) 2003-07-31
CA2327547C (en) 2009-10-27
EP1068358A1 (de) 2001-01-17
ATE320508T1 (de) 2006-04-15

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