ZA9811162B
(en)
|
1997-12-12 |
2000-06-07 |
Genentech Inc |
Treatment with anti-ERBB2 antibodies.
|
IL139035A0
(en)
*
|
1998-05-06 |
2001-11-25 |
Genentech Inc |
Protein purification by ion exchange chromatography
|
EP1500661A1
(de)
|
1998-06-01 |
2005-01-26 |
Genetech, Inc. |
Trennung von Protein-Monomeren von Aggregaten mittels Ionaustausch-Chromatographie
|
US20040013667A1
(en)
*
|
1999-06-25 |
2004-01-22 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
US20030086924A1
(en)
*
|
1999-06-25 |
2003-05-08 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
WO2001083781A2
(en)
*
|
2000-04-28 |
2001-11-08 |
Millennium Pharmaceuticals, Inc. |
14094, a novel human trypsin family member and uses thereof
|
US6790709B2
(en)
*
|
2001-11-30 |
2004-09-14 |
Intel Corporation |
Backside metallization on microelectronic dice having beveled sides for effective thermal contact with heat dissipation devices
|
AU2002351353A1
(en)
|
2001-12-19 |
2003-09-02 |
Genentech, Inc. |
Stabilizing polypeptides which have been exposed to urea
|
FR2840695B1
(fr)
*
|
2002-06-07 |
2004-10-08 |
Chevrillon Philippe Ind |
Procede de fabrication de ceintures d'impression
|
US7998705B2
(en)
*
|
2002-08-06 |
2011-08-16 |
FUJIFILM Diosynth Biotechnologies U.S.A., Inc |
Increased dynamic binding capacity in ion exchange chromatography by addition of polyethylene glycol
|
EP1543038B2
(de)
|
2002-09-11 |
2020-08-05 |
Genentech, Inc. |
Proteinaufreinigung
|
TW201319088A
(zh)
*
|
2003-07-18 |
2013-05-16 |
Amgen Inc |
對肝細胞生長因子具專一性之結合劑
|
US9259573B2
(en)
|
2003-10-15 |
2016-02-16 |
Rmx, Llc |
Device and method for manipulating exhalation
|
US8140164B2
(en)
|
2003-10-15 |
2012-03-20 |
Rmx, Llc |
Therapeutic diaphragm stimulation device and method
|
US8160711B2
(en)
|
2003-10-15 |
2012-04-17 |
Rmx, Llc |
Multimode device and method for controlling breathing
|
US7979128B2
(en)
|
2003-10-15 |
2011-07-12 |
Rmx, Llc |
Device and method for gradually controlling breathing
|
US8244358B2
(en)
|
2003-10-15 |
2012-08-14 |
Rmx, Llc |
Device and method for treating obstructive sleep apnea
|
US7970475B2
(en)
|
2003-10-15 |
2011-06-28 |
Rmx, Llc |
Device and method for biasing lung volume
|
US8265759B2
(en)
|
2003-10-15 |
2012-09-11 |
Rmx, Llc |
Device and method for treating disorders of the cardiovascular system or heart
|
US8467876B2
(en)
|
2003-10-15 |
2013-06-18 |
Rmx, Llc |
Breathing disorder detection and therapy delivery device and method
|
PL1692182T3
(pl)
|
2003-11-05 |
2010-09-30 |
Roche Glycart Ag |
Przeciwciała CD20 o zwiększonym powinowactwie wiązania z receptorem Fc oraz zwiększonej funkcji efektorowej
|
WO2005074908A1
(en)
|
2004-02-06 |
2005-08-18 |
Borody, Thomas, Julius |
Use of aminosalicylates in diarrhoea-predominent irritable bowel syndrome
|
US20060234907A1
(en)
*
|
2004-02-13 |
2006-10-19 |
Werner Gehringer |
Albumin solution and process for the production thereof
|
US7713629B2
(en)
*
|
2004-03-26 |
2010-05-11 |
Florida State University Research Foundation |
Hydrophobic fluorinated polyelectrolyte complex films and associated methods
|
US9056125B2
(en)
*
|
2004-05-17 |
2015-06-16 |
Florida State University Research Foundation, Inc. |
Films for controlled cell growth and adhesion
|
SV2006002143A
(es)
*
|
2004-06-16 |
2006-01-26 |
Genentech Inc |
Uso de un anticuerpo para el tratamiento del cancer resistente al platino
|
ES2521140T3
(es)
*
|
2004-07-22 |
2014-11-12 |
Genentech, Inc. |
Composición de anticuerpos de HER2
|
JO3000B1
(ar)
*
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
KR20070085855A
(ko)
*
|
2004-12-07 |
2007-08-27 |
제넨테크, 인크. |
Her 억제제를 이용한 치료를 위한 환자 선택 방법
|
CN101141981A
(zh)
|
2005-01-21 |
2008-03-12 |
健泰科生物技术公司 |
Her抗体的固定剂量给药
|
CN101115836A
(zh)
*
|
2005-02-09 |
2008-01-30 |
健泰科生物技术公司 |
用基质金属蛋白酶拮抗剂抑制her2脱落
|
DK1850874T3
(da)
|
2005-02-23 |
2013-11-11 |
Genentech Inc |
Forlængelse af tid til sygdomsprogression eller overlevelse for ovariecancer ved anvendelse af pertuzumab
|
US7585955B2
(en)
*
|
2005-03-03 |
2009-09-08 |
Florida State University Research Foundation, Inc |
Protein separation from a protein mixture
|
WO2006096861A2
(en)
*
|
2005-03-08 |
2006-09-14 |
Genentech, Inc. |
METHODS FOR IDENTIFYING TUMORS RESPONSIVE TO TREATMENT WITH HER DIMERIZATION INHIBITORS (HDIs)
|
US7459542B2
(en)
*
|
2005-03-10 |
2008-12-02 |
Florida State University Research Foundation, Inc. |
Separation of albumin from protein samples
|
JP2006316040A
(ja)
|
2005-05-13 |
2006-11-24 |
Genentech Inc |
Herceptin(登録商標)補助療法
|
TWI391399B
(zh)
|
2005-05-25 |
2013-04-01 |
Hoffmann La Roche |
測定溶離多肽之鹽濃度之方法
|
PE20070207A1
(es)
|
2005-07-22 |
2007-03-09 |
Genentech Inc |
Tratamiento combinado de los tumores que expresan el her
|
US7452872B2
(en)
|
2005-08-24 |
2008-11-18 |
Salix Pharmaceuticals, Inc. |
Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
|
US8921344B2
(en)
|
2006-11-03 |
2014-12-30 |
Salix Pharmaceuticals, Inc. |
Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
|
KR20090005315A
(ko)
*
|
2006-04-05 |
2009-01-13 |
애보트 바이오테크놀로지 리미티드 |
항체 정제
|
AU2007321877B2
(en)
*
|
2006-08-01 |
2011-11-03 |
Kineta Two, Llc |
Pharmaceutical manufacturing methods
|
CA2661872A1
(en)
*
|
2006-08-28 |
2008-03-06 |
Ares Trading S.A. |
Process for the purification of fc-fusion proteins
|
PT2061803T
(pt)
|
2006-08-28 |
2019-11-21 |
Ares Trading Sa |
Processo de purificação de proteinas contendo fc
|
TW201516149A
(zh)
|
2006-09-13 |
2015-05-01 |
Abbvie Inc |
細胞培養改良
|
US8911964B2
(en)
|
2006-09-13 |
2014-12-16 |
Abbvie Inc. |
Fed-batch method of making human anti-TNF-alpha antibody
|
US8280513B2
(en)
|
2006-12-22 |
2012-10-02 |
Rmx, Llc |
Device and method to treat flow limitations
|
WO2008091740A2
(en)
*
|
2007-01-22 |
2008-07-31 |
Genentech, Inc. |
Polyelectrolyte precipitation and purification of antibodies
|
EP2132573B1
(de)
|
2007-03-02 |
2014-04-23 |
Genentech, Inc. |
Voraussage der reaktion auf einen her-dimerisationshemmer auf basis niedriger her3-expression
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
EP2152745B2
(de)
*
|
2007-06-01 |
2023-03-15 |
F. Hoffmann-La Roche AG |
Immunglobulinreinigung
|
PL2171090T3
(pl)
|
2007-06-08 |
2013-09-30 |
Genentech Inc |
Markery ekspresji genów odporności guza na leczenie hamujące HER2
|
US9551033B2
(en)
|
2007-06-08 |
2017-01-24 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
PL2565206T3
(pl)
*
|
2007-10-30 |
2017-08-31 |
Genentech, Inc. |
Oczyszczanie przeciwciał za pomocą chromatografii kationowymiennej
|
AU2012227163B2
(en)
*
|
2007-10-30 |
2015-07-16 |
Genentech, Inc. |
Antibody purification by cation exchange chromatography
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
EP2769991B1
(de)
|
2008-01-03 |
2018-08-22 |
The Scripps Research Institute |
Antikörper-targeting mittels modularer erkennungsdomäne
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
EP2644204B1
(de)
|
2008-03-18 |
2017-04-19 |
Genentech, Inc. |
Kombination aus einem Anti-HER2-Antikörperwirkstoffkonjugat und Pertuzumab
|
EP2282769A4
(de)
|
2008-04-29 |
2012-04-25 |
Abbott Lab |
Dual-variable- domain-immunglobuline und ihre verwendungen
|
KR20110016959A
(ko)
|
2008-06-03 |
2011-02-18 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
JP2011523853A
(ja)
|
2008-06-03 |
2011-08-25 |
アボット・ラボラトリーズ |
二重可変ドメイン免疫グロブリン及びその使用
|
BRPI0812682A2
(pt)
|
2008-06-16 |
2010-06-22 |
Genentech Inc |
tratamento de cáncer de mama metastático
|
WO2010009271A2
(en)
|
2008-07-15 |
2010-01-21 |
Academia Sinica |
Glycan arrays on ptfe-like aluminum coated glass slides and related methods
|
ES2527943T5
(es)
|
2008-08-14 |
2019-03-07 |
Genentech Inc |
Métodos para eliminar un contaminante usando cromatografía de membrana de intercambio iónico de desplazamiento de proteínas
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
AU2008221604B2
(en)
*
|
2008-09-22 |
2010-04-22 |
Commonwealth Scientific And Industrial Research Organisation |
Temperature-responsive polymer particles in protein separation applications
|
JP5913980B2
(ja)
|
2008-10-14 |
2016-05-11 |
ジェネンテック, インコーポレイテッド |
免疫グロブリン変異体及びその用途
|
CN105111309A
(zh)
|
2008-10-20 |
2015-12-02 |
Abbvie公司 |
使用a蛋白亲和层析分离和纯化抗体
|
CN102257005A
(zh)
|
2008-10-20 |
2011-11-23 |
雅培制药有限公司 |
在抗体纯化过程中的病毒灭活
|
MX2011004558A
(es)
*
|
2008-10-29 |
2011-06-01 |
Wyeth Llc |
Procedimientos para la purificacion de moleculas de union a antigeno de un unico dominio.
|
WO2010099186A1
(en)
*
|
2009-02-25 |
2010-09-02 |
Merck Sharp & Dohme Corp. |
Her2 antibody compositions
|
TWI461211B
(zh)
|
2009-03-20 |
2014-11-21 |
Genentech Inc |
抗-her抗體
|
JP5863640B2
(ja)
*
|
2009-04-29 |
2016-02-16 |
バイオ−ラッド ラボラトリーズ インコーポレーティッド |
免疫複合体の精製
|
SG176073A1
(en)
|
2009-05-29 |
2011-12-29 |
Hoffmann La Roche |
Modulators for her2 signaling in her2 expressing patients with gastric cancer
|
BRPI1010068A2
(pt)
|
2009-07-24 |
2016-03-15 |
Hoffmann La Roche |
"sistema agitador, dispositivo, método para cultivo de células animais, método para produzir um polipeptídeo, uso de um sistema agitador e dispositivos para cultivar células animais"
|
BRPI1010119A2
(pt)
*
|
2009-07-24 |
2016-03-15 |
Hoffmann La Roche |
"método de produção de composição de anticorpo e uso de cromatografia de troca de íons analítica"
|
US9345661B2
(en)
|
2009-07-31 |
2016-05-24 |
Genentech, Inc. |
Subcutaneous anti-HER2 antibody formulations and uses thereof
|
SG178478A1
(en)
*
|
2009-08-20 |
2012-04-27 |
Baxter Int |
Purification of vwf for increased removal of non-lipid enveloped viruses
|
SG178602A1
(en)
|
2009-09-01 |
2012-04-27 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
CN103980346A
(zh)
|
2009-10-01 |
2014-08-13 |
弗·哈夫曼-拉罗切有限公司 |
多步骤的最终过滤
|
BR112012008833A2
(pt)
|
2009-10-15 |
2015-09-08 |
Abbott Lab |
imunoglobulinas de dominio variavel duplo e usos das mesmas
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
US8304248B2
(en)
|
2009-11-16 |
2012-11-06 |
Torres Anthony R |
Protein separation via ion-exchange chromatography and associated methods, systems, and devices
|
US8697844B2
(en)
*
|
2009-11-24 |
2014-04-15 |
Novo Nordisk A/S |
Method of purifying pegylated proteins
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
US20110165155A1
(en)
*
|
2009-12-04 |
2011-07-07 |
Genentech, Inc. |
Methods of treating metastatic breast cancer with trastuzumab-mcc-dm1
|
KR20120123299A
(ko)
*
|
2009-12-04 |
2012-11-08 |
제넨테크, 인크. |
다중특이적 항체, 항체 유사체, 조성물 및 방법
|
RU2564569C2
(ru)
|
2009-12-18 |
2015-10-10 |
Новартис Аг |
Промывочный раствор и способ промывки для аффинной хроматографии
|
US9556249B2
(en)
|
2010-02-18 |
2017-01-31 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
KR101152036B1
(ko)
|
2010-04-27 |
2012-06-08 |
(주)셀트리온 |
컬럼 순환 및 시료 연속주입법을 이용한 단백질 a 크로마토그래피 정제 방법
|
DK2568976T3
(en)
|
2010-05-10 |
2016-01-11 |
Academia Sinica |
Zanamivir-phosphonate congener with the anti-influenza activity, and determining the sensitivity oseltamivir in influenza viruses
|
US20110301342A1
(en)
*
|
2010-05-18 |
2011-12-08 |
Abbott Laboratories, Inc. |
Apparatus and process for purification of proteins
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
CA2799915C
(en)
*
|
2010-05-25 |
2023-09-26 |
Genentech, Inc. |
Methods of purifying polypeptides
|
BR112012030179A8
(pt)
*
|
2010-05-27 |
2023-03-14 |
Merck Sharp & Dohme |
Polipeptídeo contendo fc
|
US20120100166A1
(en)
|
2010-07-15 |
2012-04-26 |
Zyngenia, Inc. |
Ang-2 Binding Complexes and Uses Thereof
|
GB201012603D0
(en)
|
2010-07-27 |
2010-09-08 |
Ucb Pharma Sa |
Protein purification
|
MX341579B
(es)
|
2010-08-03 |
2016-08-25 |
Abbvie Inc * |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
NZ604510A
(en)
|
2010-08-17 |
2013-10-25 |
Csl Ltd |
Dilutable biocidal compositions and methods of use
|
AU2011293253B2
(en)
|
2010-08-26 |
2014-12-11 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
JPWO2012029990A1
(ja)
*
|
2010-09-01 |
2013-10-31 |
株式会社バイオマトリックス研究所 |
大腸がんマーカーに対する抗体
|
BR112013007293A2
(pt)
|
2010-10-05 |
2016-06-14 |
Hoffmann La Roche |
anticorpos contra a tweak de seres humanos e suas utilizações
|
JP6023715B2
(ja)
*
|
2010-10-11 |
2016-11-09 |
アッヴィ・バハマズ・リミテッド |
タンパク質の精製方法
|
EP2643353A1
(de)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispezifische moleküle
|
US20120149878A1
(en)
*
|
2010-12-08 |
2012-06-14 |
Gillespie Ronald |
Protein purification
|
RU2586515C2
(ru)
|
2010-12-21 |
2016-06-10 |
Ф.Хоффманн-Ля Рош Аг |
Препарат антитела, обогащенного изоформами и способ его получения
|
WO2012085111A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
KR101940829B1
(ko)
|
2011-03-03 |
2019-01-21 |
아를라 푸즈 에이엠비에이 |
Cmp 또는 카제인 종을 함유하는 원료를 이용한 오스테오폰틴의 단리 방법
|
EP2686016B1
(de)
|
2011-03-14 |
2019-05-01 |
Cellmid Limited |
Antikörper zur erkennung der n-domäne von midkin
|
EP2702077A2
(de)
|
2011-04-27 |
2014-03-05 |
AbbVie Inc. |
Verfahren zur steuerung des galactosylierungsprofil von rekombinant exprimierten proteinen
|
ES2704038T3
(es)
|
2011-05-24 |
2019-03-13 |
Zyngenia Inc |
Complejos multiespecíficos multivalentes y monovalentes y sus usos
|
CA2838246C
(en)
|
2011-06-13 |
2018-07-10 |
Csl Limited |
Antibodies against g-csfr and uses thereof
|
EP2744824A1
(de)
|
2011-08-17 |
2014-06-25 |
F.Hoffmann-La Roche Ag |
Neuregulin-antikörper und verwendungen davon
|
US9365881B2
(en)
|
2011-10-05 |
2016-06-14 |
Hoffmann-La Roche Inc. |
Process for antibody G1 glycoform production
|
UA123092C2
(uk)
*
|
2011-10-14 |
2021-02-17 |
Дженентек, Інк. |
Спосіб неоад'ювантного лікування her2-позитивного раку молочної залози на ранній стадії у пацієнта
|
WO2013063229A1
(en)
|
2011-10-25 |
2013-05-02 |
The Regents Of The University Of Michigan |
Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells
|
US9265817B2
(en)
|
2011-10-28 |
2016-02-23 |
Patrys Limited |
PAT-LM1 epitopes and methods for using same
|
US20140288278A1
(en)
*
|
2011-10-31 |
2014-09-25 |
Joseph Nti-Gyabaah |
Chromatography process for resolving heterogeneous antibody aggregates
|
RU2014121884A
(ru)
*
|
2011-11-02 |
2015-12-10 |
Дженентек, Инк. |
Хроматография перегрузки и элюирования
|
CA2857114A1
(en)
|
2011-11-30 |
2013-06-06 |
Genentech, Inc. |
Erbb3 mutations in cancer
|
US9376715B2
(en)
|
2011-12-09 |
2016-06-28 |
Roche Molecular Systems, Inc |
Methods for detecting mutations in the catalytic subunit of the phosphoinositol-3 kinase (PIK3CA) gene
|
WO2013096812A1
(en)
|
2011-12-23 |
2013-06-27 |
Genentech, Inc. |
Articles of manufacture and methods for co-administration of antibodies
|
CA2861610A1
(en)
|
2011-12-30 |
2013-07-04 |
Abbvie Inc. |
Dual specific binding proteins directed against il-13 and/or il-17
|
EP2831115A1
(de)
|
2012-03-27 |
2015-02-04 |
F. Hoffmann-La Roche AG |
Diagnose und behandlungen im zusammenhang mit her3-hemmern
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
WO2013158273A1
(en)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Methods to modulate c-terminal lysine variant distribution
|
WO2013158279A1
(en)
*
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Protein purification methods to reduce acidic species
|
WO2013176754A1
(en)
|
2012-05-24 |
2013-11-28 |
Abbvie Inc. |
Novel purification of antibodies using hydrophobic interaction chromatography
|
US9738724B2
(en)
|
2012-06-08 |
2017-08-22 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
EP2863955B1
(de)
*
|
2012-06-26 |
2016-11-23 |
Sutro Biopharma, Inc. |
Modifizierte fc-proteine mit nichtnatürlichen ortsspezifische aminosäureresten, konjugate daraus, verfahren zu deren herstellung und verfahren zu deren verwendung
|
JP6302909B2
(ja)
|
2012-08-18 |
2018-03-28 |
アカデミア シニカAcademia Sinica |
シアリダーゼの同定および画像化のための細胞透過性プローブ
|
CA2883168A1
(en)
|
2012-08-21 |
2014-02-27 |
Academia Sinica |
Benzocyclooctyne compounds and uses thereof
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
AU2013309506A1
(en)
|
2012-09-02 |
2015-03-12 |
Abbvie Inc. |
Methods to control protein heterogeneity
|
TW202210507A
(zh)
|
2012-11-01 |
2022-03-16 |
美商艾伯維有限公司 |
抗-vegf/dll4雙重可變區域免疫球蛋白及其用途
|
JP6998646B2
(ja)
|
2012-11-30 |
2022-02-04 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Pd-l1阻害剤併用療法を必要とする患者の同定
|
WO2014118685A2
(en)
*
|
2013-01-29 |
2014-08-07 |
Dr. Reddy's Laboratories Limited |
Method of altering the acidic variant content of antibody
|
CN104995211B
(zh)
|
2013-02-07 |
2019-09-13 |
Csl有限公司 |
Il-11r结合蛋白及其应用
|
CN105377874A
(zh)
|
2013-03-08 |
2016-03-02 |
建新公司 |
治疗性蛋白药物物质的整合连续制造
|
SG11201507230PA
(en)
|
2013-03-12 |
2015-10-29 |
Abbvie Inc |
Human antibodies that bind human tnf-alpha and methods of preparing the same
|
US10023608B1
(en)
|
2013-03-13 |
2018-07-17 |
Amgen Inc. |
Protein purification methods to remove impurities
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
WO2014159579A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
|
JP6285532B2
(ja)
|
2013-03-14 |
2018-02-28 |
イー・エム・デイー・ミリポア・コーポレイシヨン |
タンパク質aに基づくクロマトグラフィを使用するタンパク質純度を増加させる方法
|
WO2014151878A2
(en)
|
2013-03-14 |
2014-09-25 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
|
US9062108B2
(en)
|
2013-03-15 |
2015-06-23 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-1 and/or IL-17
|
BR112015023752B1
(pt)
|
2013-03-15 |
2023-11-14 |
Zyngenia, Inc. |
Domínio de reconhecimento modular (mrd), complexo compreendendo mrd e cetuximabe, usos do complexo para inibir a angiogênese e tratar câncer e composição farmacêutica compreendendo o dito complexo
|
EP3800204A1
(de)
|
2013-04-16 |
2021-04-07 |
F. Hoffmann-La Roche AG |
Pertuzumab-varianten und evaluierung davon
|
AR096713A1
(es)
|
2013-06-25 |
2016-01-27 |
Cadila Healthcare Ltd |
Proceso de purificación para anticuerpos monoclonales
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
WO2014210564A1
(en)
|
2013-06-27 |
2014-12-31 |
Academia Sinica |
Glycan conjugates and use thereof
|
ES2658039T3
(es)
|
2013-07-10 |
2018-03-08 |
Sutro Biopharma, Inc. |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
EP3536699A1
(de)
|
2013-07-12 |
2019-09-11 |
F. Hoffmann-La Roche AG |
Darstellung einer eingabeoptimierung in der ionenaustauschchromatografie
|
CA2923579C
(en)
|
2013-09-06 |
2023-09-05 |
Academia Sinica |
Human inkt cell activation using glycolipids with altered glycosyl groups
|
SG11201602061YA
(en)
*
|
2013-09-17 |
2016-04-28 |
Kaneka Corp |
Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom
|
EP3052640A2
(de)
|
2013-10-04 |
2016-08-10 |
AbbVie Inc. |
Verwendung von metallionen zur modulation von proteinglykosylierungsprofilen rekombinanter proteine
|
KR102356757B1
(ko)
*
|
2013-10-18 |
2022-02-03 |
노바셉 이큅먼트 솔루션즈 |
단백질 정제
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
WO2015064971A1
(ko)
*
|
2013-10-30 |
2015-05-07 |
(주)셀트리온 |
양이온 교환 크로마토그래피를 이용한 항체의 아형 분리 방법
|
CN104628846B
(zh)
*
|
2013-11-06 |
2019-12-06 |
三生国健药业(上海)股份有限公司 |
重组蛋白质的纯化方法
|
WO2015073884A2
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
CA2937123A1
(en)
|
2014-01-16 |
2015-07-23 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
TWI709569B
(zh)
|
2014-01-17 |
2020-11-11 |
美商健臻公司 |
無菌層析樹脂及其用於製造方法的用途
|
TWI709570B
(zh)
|
2014-01-17 |
2020-11-11 |
美商健臻公司 |
無菌層析法及製法
|
CN106415244B
(zh)
|
2014-03-27 |
2020-04-24 |
中央研究院 |
反应性标记化合物及其用途
|
WO2015164665A1
(en)
|
2014-04-25 |
2015-10-29 |
Genentech, Inc. |
Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab
|
EP3149036A4
(de)
|
2014-05-27 |
2017-12-27 |
Academia Sinica |
Anti-cd20-glycoantikörper und verwendungen davon
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
EP4116329A1
(de)
*
|
2014-05-27 |
2023-01-11 |
Academia Sinica |
Anti-her2-glykoantikörper und verwendungen davon
|
TWI717319B
(zh)
|
2014-05-27 |
2021-02-01 |
中央研究院 |
得自類桿菌屬之岩藻糖苷酶及其用途
|
TWI732738B
(zh)
|
2014-05-28 |
2021-07-11 |
中央研究院 |
抗TNF-α醣抗體及其用途
|
MX2016017115A
(es)
*
|
2014-06-25 |
2018-01-12 |
Jhl Biotech Inc |
Metodos y reactivos para la purificacion de proteinas.
|
CN105315369B
(zh)
*
|
2014-07-25 |
2020-03-13 |
山东博安生物技术有限公司 |
利用阳离子交换层析纯化蛋白质
|
WO2016033245A1
(en)
|
2014-08-26 |
2016-03-03 |
Rmx, Llc |
Devices and methods for reducing intrathoracic pressure
|
CA2960712A1
(en)
|
2014-09-08 |
2016-03-17 |
Academia Sinica |
Human inkt cell activation using glycolipids
|
JP2017528468A
(ja)
|
2014-09-10 |
2017-09-28 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ガラクトース操作型免疫グロブリン1抗体
|
JP2021006540A
(ja)
*
|
2014-09-10 |
2021-01-21 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ガラクトース操作型免疫グロブリン1抗体
|
ES2830385T3
(es)
|
2014-09-12 |
2021-06-03 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-HER2
|
BR112017004953A2
(pt)
|
2014-09-17 |
2017-12-05 |
Genentech Inc |
imunoconjugado, formulação farmacêutica, método de tratamento e método de inibição da proliferação de uma célula
|
US10584175B2
(en)
|
2014-10-23 |
2020-03-10 |
La Trobe University |
FN14-binding proteins and uses thereof
|
MX2017005148A
(es)
|
2014-11-06 |
2017-08-08 |
Hoffmann La Roche |
Variantes de region fc con union del receptor fc neonatal (fcrn) modificado y metodos de uso.
|
KR101531479B1
(ko)
*
|
2014-11-21 |
2015-06-26 |
세원셀론텍(주) |
의료용 재료로 사용하기 위한 고농도 콜라겐 제조방법
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
AU2015367224B2
(en)
|
2014-12-19 |
2020-12-10 |
Monash University |
IL-21 antibodies
|
CN110658340B
(zh)
*
|
2015-01-08 |
2023-10-31 |
苏州康宁杰瑞生物科技有限公司 |
具有共同轻链的双特异性抗体或抗体混合物
|
SG10202111844VA
(en)
|
2015-01-09 |
2021-12-30 |
Adalta Ltd |
Cxcr4 binding molecules
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
WO2016118707A1
(en)
*
|
2015-01-21 |
2016-07-28 |
Oncobiologics, Inc. |
Modulation of charge variants in a monoclonal antibody composition
|
CA2972072A1
(en)
|
2015-01-24 |
2016-07-28 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
CA2978095C
(en)
*
|
2015-03-13 |
2022-02-15 |
Bristol-Myers Squibb Company |
Use of alkaline washes during chromatography to remove impurities
|
US11406715B2
(en)
|
2015-05-30 |
2022-08-09 |
Genentech, Inc. |
Methods of treating HER2-positive metastatic breast cancer
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
WO2016205176A1
(en)
|
2015-06-15 |
2016-12-22 |
Genentech, Inc. |
Antibodies and immunoconjugates
|
ES2731377T3
(es)
|
2015-07-07 |
2019-11-15 |
Hoffmann La Roche |
Politerapia con un conjugado anticuerpo anti-HER2-fármaco y un inhibidor de bcl-2
|
WO2017087280A1
(en)
|
2015-11-16 |
2017-05-26 |
Genentech, Inc. |
Methods of treating her2-positive cancer
|
SG11201804083QA
(en)
*
|
2015-11-18 |
2018-06-28 |
Merck Patent Gmbh |
Opposite ph-salt gradients for improved protein separations
|
AU2016355739A1
(en)
*
|
2015-11-18 |
2018-07-05 |
Merck Patent Gmbh |
Improved protein separation in ion exchange chromatography
|
CA3011455A1
(en)
|
2016-01-27 |
2017-08-03 |
Sutro Biopharma, Inc. |
Anti-cd74 antibody conjugates, compositions comprising anti-cd74 antibody conjugates and methods of using anti-cd74 antibody conjugates
|
EP3411401A1
(de)
|
2016-02-03 |
2018-12-12 |
Oncobiologics, Inc. |
Pufferformulierungen für verstärkte antikörperstabilität
|
CA3016170A1
(en)
|
2016-03-08 |
2017-09-14 |
Academia Sinica |
Methods for modular synthesis of n-glycans and arrays thereof
|
EP3454863A1
(de)
|
2016-05-10 |
2019-03-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Kombinationstherapien zur behandlung von krebs
|
PL3484911T3
(pl)
*
|
2016-07-15 |
2021-03-08 |
F. Hoffmann-La Roche Ag |
Sposób oczyszczania PEGylowanej erytropoetyny
|
CA3034057A1
(en)
|
2016-08-22 |
2018-03-01 |
CHO Pharma Inc. |
Antibodies, binding fragments, and methods of use
|
JP7424727B2
(ja)
|
2016-09-29 |
2024-01-30 |
ベイジン・ハンミ・ファーマシューティカル・カンパニー・リミテッド |
ヘテロダイマー免疫グロブリン構造体及びその製造方法
|
KR20190075114A
(ko)
|
2016-11-04 |
2019-06-28 |
제넨테크, 인크. |
Her2-양성 유방암의 치료
|
KR102247704B1
(ko)
*
|
2016-11-18 |
2021-05-03 |
북경한미약품 유한공사 |
항 pd-1/항 her2 천연항체 구조 형태의 헤테로다이머 계의 이중특이성 항체 및 그 제조방법
|
CA3046092A1
(en)
|
2016-12-28 |
2018-07-05 |
Genentech, Inc. |
Treatment of advanced her2 expressing cancer
|
UA123292C2
(uk)
|
2017-01-17 |
2021-03-10 |
Дженентек, Інк. |
Рідка фармацевтична композиція, яка містить пертузумаб та трастузумаб
|
US11077189B2
(en)
|
2017-03-02 |
2021-08-03 |
Genentech Inc. |
Adjuvant treatment of HER2-positive breast cancer
|
AU2018258263A1
(en)
|
2017-04-24 |
2019-10-24 |
Genentech, Inc. |
ErbB2/Her2 mutations in the transmembrane or juxtamembrane domain
|
CN107602702A
(zh)
|
2017-09-22 |
2018-01-19 |
生标(上海)医疗器械科技有限公司 |
一种同时靶向人p185和血管内皮生长因子的抗体及其应用
|
CN108101987A
(zh)
*
|
2017-11-17 |
2018-06-01 |
安徽未名生物医药有限公司 |
一种重组抗TNF-α全人源单克隆抗体的纯化方法
|
US20210179721A1
(en)
|
2017-11-29 |
2021-06-17 |
Csl Limited |
Method of treating or preventing ischemia-reperfusion injury
|
WO2019153200A1
(zh)
|
2018-02-08 |
2019-08-15 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
TW202003561A
(zh)
|
2018-03-13 |
2020-01-16 |
瑞士商赫孚孟拉羅股份公司 |
使用靶向4-1bb (cd137)之促效劑的組合療法
|
EA202092335A1
(ru)
|
2018-04-02 |
2021-01-22 |
Эмджен Инк. |
Композиции на основе эренумаба и пути их применения
|
MX2020010732A
(es)
|
2018-04-13 |
2020-11-09 |
Hoffmann La Roche |
Moleculas de union a antigeno dirigidas a her2 que comprenden 4-1bbl.
|
SG11202101860UA
(en)
|
2018-08-31 |
2021-03-30 |
Genzyme Corp |
Sterile chromatography resin and use thereof in manufacturing processes
|
US20210340279A1
(en)
|
2018-08-31 |
2021-11-04 |
Yale University |
Compositions and methods of using cell-penetrating antibodies in combination with immune checkpoint modulators
|
CN112867736A
(zh)
|
2018-10-15 |
2021-05-28 |
豪夫迈·罗氏有限公司 |
用曲妥珠单抗美坦新治疗残存乳腺癌的方法
|
CN111196856A
(zh)
*
|
2018-11-19 |
2020-05-26 |
三生国健药业(上海)股份有限公司 |
抗her2/pd1双特异性抗体
|
WO2020208049A1
(en)
|
2019-04-12 |
2020-10-15 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecules comprising lipocalin muteins
|
WO2020234742A1
(en)
|
2019-05-20 |
2020-11-26 |
Lupin Limited |
Granulocyte colony stimulating factor purification
|
WO2020252294A1
(en)
|
2019-06-13 |
2020-12-17 |
Bolt Biotherapeutics, Inc. |
Aminobenzazepine compounds, immunoconjugates, and uses thereof
|
US11266838B1
(en)
|
2019-06-21 |
2022-03-08 |
Rmx, Llc |
Airway diagnostics utilizing phrenic nerve stimulation device and method
|
CN110339209B
(zh)
*
|
2019-07-18 |
2023-06-06 |
上海泰坦科技股份有限公司 |
一种去甲状腺结合蛋白的小牛血清的制备方法
|
JP2022546110A
(ja)
|
2019-09-03 |
2022-11-02 |
ボルト バイオセラピューティクス、インコーポレーテッド |
アミノキノリン化合物、免疫複合体、及びそれらの使用
|
EP4038053A1
(de)
|
2019-09-30 |
2022-08-10 |
Bolt Biotherapeutics, Inc. |
Amid-verbundene, aminobenzazepin-immunkonjugate und verwendungen davon
|
US20220396598A1
(en)
*
|
2019-10-14 |
2022-12-15 |
Pierce Biotechnology, Inc. |
Peptide purification formulations and methods
|
MX2022004875A
(es)
|
2019-10-25 |
2022-06-17 |
Bolt Biotherapeutics Inc |
Inmunoconjugados de tienoazepina, inmunoconjugados y usos de estos.
|
CA3159770A1
(en)
|
2019-11-15 |
2021-05-20 |
Seagen Inc. |
Methods of treating her2 positive breast cancer with tucatinib in combination with an anti-her2 antibody-drug conjugate
|
EP4077385A4
(de)
|
2019-12-20 |
2023-12-13 |
Hudson Institute of Medical Research |
Cxcl10-bindende proteine und verwendungen davon
|
US20230293716A1
(en)
|
2020-05-08 |
2023-09-21 |
Bolt Biotherapeutics, Inc. |
Elastase-substrate, peptide linker immunoconjugates, and uses thereof
|
TW202216769A
(zh)
|
2020-06-23 |
2022-05-01 |
瑞士商赫孚孟拉羅股份公司 |
靶向her2的激動性cd28抗原結合分子
|
IL299376A
(en)
|
2020-06-29 |
2023-02-01 |
Genentech Inc |
Fixed dose combination of pertuzumab plus transtuzumab
|
MX2023000622A
(es)
|
2020-07-14 |
2023-02-22 |
Genentech Inc |
Ensayos para combinaciones de dosis fija.
|
EP4182475A2
(de)
|
2020-07-17 |
2023-05-24 |
Onena Medicines S.L. |
Antikörper gegen linksprotein
|
EP4196168A1
(de)
|
2020-08-13 |
2023-06-21 |
Bolt Biotherapeutics, Inc. |
Pyrazoloazepin-immunkonjugate und verwendungen davon
|
CN112430252B
(zh)
*
|
2020-11-13 |
2022-09-02 |
宜昌东阳光长江药业股份有限公司 |
一种提高目标蛋白回收率的层析方法
|
CN116744978A
(zh)
|
2020-12-11 |
2023-09-12 |
博尔特生物治疗药物有限公司 |
抗her2免疫缀合物及其用途
|
JP2023552791A
(ja)
|
2020-12-11 |
2023-12-19 |
ボルト バイオセラピューティクス、インコーポレーテッド |
抗her2免疫複合体、及びその使用
|
JP2024501445A
(ja)
|
2020-12-11 |
2024-01-12 |
ジェネンテック, インコーポレイテッド |
Her2がんの処置のための併用療法
|
JP2024511088A
(ja)
|
2021-03-26 |
2024-03-12 |
ボルト バイオセラピューティクス、インコーポレーテッド |
2-アミノ-4-カルボキサミド-ベンゾアゼピン免疫複合体、及びその使用
|
JP2024512056A
(ja)
|
2021-03-26 |
2024-03-18 |
ボルト バイオセラピューティクス、インコーポレーテッド |
2-アミノ-4-カルボキサミド-ベンゾアゼピン免疫複合体、及びその使用
|
AU2022249371A1
(en)
|
2021-04-01 |
2023-10-26 |
Vestaron Corporation |
Av3 mutant polypeptides for pest control
|
CN113769794B
(zh)
*
|
2021-07-06 |
2024-04-05 |
沁浩膜技术(厦门)有限公司 |
一种连续脱除胞磷胆碱钠中杂质的离子交换系统及方法
|
CA3234604A1
(en)
|
2021-10-29 |
2023-05-04 |
Shelley Erin ACKERMAN |
Tlr agonist immunoconjugates with cysteine-mutant antibodies, and uses thereof
|
WO2023122805A1
(en)
|
2021-12-20 |
2023-06-29 |
Vestaron Corporation |
Sorbitol driven selection pressure method
|
CN114230641B
(zh)
*
|
2021-12-29 |
2024-03-26 |
内蒙古必威安泰生物科技有限公司 |
一种去除口蹄疫抗原液中内毒素的方法
|
WO2023192924A1
(en)
|
2022-03-30 |
2023-10-05 |
Vestaron Corporation |
Combinations of av3 mutant polypeptides and bt toxins for pest control
|
WO2023225555A1
(en)
|
2022-05-18 |
2023-11-23 |
Vestaron Corporation |
Pesticidal actx peptide variants
|
WO2023245100A1
(en)
|
2022-06-17 |
2023-12-21 |
Vestaron Corporation |
Antimicrobial ncr13 variant peptides
|
WO2024026406A2
(en)
|
2022-07-29 |
2024-02-01 |
Vestaron Corporation |
Next Generation ACTX Peptides
|
WO2024038198A1
(en)
|
2022-08-18 |
2024-02-22 |
Immunocore Limited |
Multi-domain binding molecules
|
WO2024038183A1
(en)
|
2022-08-18 |
2024-02-22 |
Immunocore Limited |
Multi-domain binding molecules
|
WO2024038193A1
(en)
|
2022-08-18 |
2024-02-22 |
Immunocore Limited |
Multi-domain binding molecules
|