DE69942975D1 - Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern - Google Patents

Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern

Info

Publication number
DE69942975D1
DE69942975D1 DE69942975T DE69942975T DE69942975D1 DE 69942975 D1 DE69942975 D1 DE 69942975D1 DE 69942975 T DE69942975 T DE 69942975T DE 69942975 T DE69942975 T DE 69942975T DE 69942975 D1 DE69942975 D1 DE 69942975D1
Authority
DE
Germany
Prior art keywords
warmers
apparent
probe
object carrier
independent object
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69942975T
Other languages
English (en)
Inventor
William Richards
Charles D Lemme
Kimberly Christensen
Ethel R Macrea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ventana Medical Systems Inc
Original Assignee
Ventana Medical Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Medical Systems Inc filed Critical Ventana Medical Systems Inc
Application granted granted Critical
Publication of DE69942975D1 publication Critical patent/DE69942975D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
DE69942975T 1998-02-27 1999-02-26 Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern Expired - Lifetime DE69942975D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7619898P 1998-02-27 1998-02-27
PCT/US1999/004181 WO1999044030A1 (en) 1998-02-27 1999-02-26 Automated molecular pathology apparatus having independent slide heaters

Publications (1)

Publication Number Publication Date
DE69942975D1 true DE69942975D1 (de) 2011-01-05

Family

ID=22130540

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69942975T Expired - Lifetime DE69942975D1 (de) 1998-02-27 1999-02-26 Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern

Country Status (10)

Country Link
US (1) US6296809B1 (de)
EP (3) EP1056541B1 (de)
JP (5) JP2002504694A (de)
CN (1) CN100403008C (de)
AT (1) ATE489613T1 (de)
AU (3) AU763354B2 (de)
CA (2) CA2321836C (de)
DE (1) DE69942975D1 (de)
ES (1) ES2354598T3 (de)
WO (2) WO1999043434A1 (de)

Families Citing this family (238)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040191128A1 (en) * 1992-05-11 2004-09-30 Cytologix Corporation Slide stainer with heating
US6180061B1 (en) 1992-05-11 2001-01-30 Cytologix Corporation Moving platform slide stainer with heating elements
US6735531B2 (en) 1996-10-07 2004-05-11 Lab Vision Corporation Method and apparatus for automatic tissue staining
JP3750772B2 (ja) * 1998-01-27 2006-03-01 富士写真フイルム株式会社 生化学分析装置
GB9803684D0 (en) * 1998-02-24 1998-04-15 Genevac Ltd Method and apparatus for controlling temperature during evaporation of samples
US6582962B1 (en) * 1998-02-27 2003-06-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US6183693B1 (en) * 1998-02-27 2001-02-06 Cytologix Corporation Random access slide stainer with independent slide heating regulation
US7396508B1 (en) 2000-07-12 2008-07-08 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US7188001B2 (en) * 1998-03-23 2007-03-06 Cepheid System and method for temperature control
US6495106B1 (en) * 1998-03-24 2002-12-17 Biogenex Laboratories Automated staining apparatus
US6620620B1 (en) * 1998-04-27 2003-09-16 Era Systems, Inc. Micro liquid evaporator
US7550298B2 (en) * 1998-09-03 2009-06-23 Ventana Medical Systems, Inc. Automated immunohistochemical and in situ hybridization assay formulations
US6855552B2 (en) * 1998-09-03 2005-02-15 Ventana Medical Systems Automated immunohistochemical and in situ hybridization assay formulations
US6649128B1 (en) * 1998-09-23 2003-11-18 Randox Laboratories Ltd Assay device processing instrument
US6544798B1 (en) * 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6706519B1 (en) * 1999-06-22 2004-03-16 Tecan Trading Ag Devices and methods for the performance of miniaturized in vitro amplification assays
US7897106B2 (en) 1999-07-08 2011-03-01 Lee Angros Situ heat induced antigen recovery and staining apparatus and method
US8298485B2 (en) * 1999-07-08 2012-10-30 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
US7951612B2 (en) * 1999-07-08 2011-05-31 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
WO2001004634A1 (en) * 1999-07-08 2001-01-18 Lee Angros Antigen recovery and/or staining apparatus and method
EP1135680A4 (de) * 1999-09-24 2004-12-15 Ventana Med Syst Inc Hochdurchsatzsystem zum bewerten des klinischen nutzens von molekularen zielmolekülen in gewebeproben
US6403931B1 (en) 1999-10-07 2002-06-11 Ventana Medical Systems, Inc. Slide heater calibrator and temperature converter apparatus and method
DE10006084B4 (de) * 2000-02-11 2009-01-02 Leica Biosystems Nussloch Gmbh Färbeautomat mit einer Heizstation
US6824738B1 (en) * 2000-04-14 2004-11-30 Discovery Partners International, Inc. System and method for treatment of samples on solid supports
DE10041227B4 (de) * 2000-08-22 2011-12-29 Leica Biosystems Nussloch Gmbh Vorrichtung zur Behandlung von Objekten
US6656685B2 (en) * 2001-01-29 2003-12-02 Ventana Medical Systems, Inc. Hybridization buffers using low molecular weight dextran sulfate and methods for their use
GB0117706D0 (en) * 2001-02-16 2001-09-12 Aventis Pharm Prod Inc Automated semi-solid matrix assay and liquid handler apparatus for the same
US7888060B2 (en) * 2001-03-30 2011-02-15 Nanoprobes, Inc. Method for detecting a target using enzyme directed deposition of elemental metal
US7691598B2 (en) * 2001-03-30 2010-04-06 Nanoprobes, Inc. Method for detecting a target molecule by metal deposition
US6662136B2 (en) * 2001-04-10 2003-12-09 International Business Machines Corporation Digital temperature sensor (DTS) system to monitor temperature in a memory subsystem
WO2002088396A2 (en) * 2001-04-30 2002-11-07 Ventana Medical Systems, Inc. Reagents and methods for automated in situ or microarray hybridization
US7425306B1 (en) 2001-09-11 2008-09-16 Ventana Medical Systems, Inc. Slide heater
US7270785B1 (en) * 2001-11-02 2007-09-18 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms
US6936474B2 (en) * 2001-11-05 2005-08-30 Industrial Technology Research Institute Method and apparatus for manufacturing biochip
WO2003042788A2 (en) 2001-11-13 2003-05-22 Chromavision Medical Systems, Inc. A system for tracking biological samples
US6998270B2 (en) * 2001-11-26 2006-02-14 Lab Vision Corporation Automated tissue staining system and reagent container
US20040033163A1 (en) * 2001-11-26 2004-02-19 Lab Vision Corporation Automated tissue staining system and reagent container
US6889468B2 (en) * 2001-12-28 2005-05-10 3M Innovative Properties Company Modular systems and methods for using sample processing devices
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
EP1494808B1 (de) 2002-04-15 2013-07-03 Ventana Medical Systems, Inc. Automatisiertes objektträgeranfärbesystem mit hohem durchsatz
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
WO2003091710A1 (en) * 2002-04-26 2003-11-06 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms
US6833536B2 (en) * 2002-05-22 2004-12-21 Applera Corporation Non-contact radiant heating and temperature sensing device for a chemical reaction chamber
WO2003099222A2 (en) * 2002-05-23 2003-12-04 Invitrogen Corporation Pseudo-tissues and uses thereof
JP2005533255A (ja) * 2002-07-16 2005-11-04 ベンタナ・メデイカル・システムズ・インコーポレーテツド 自動化された組織化学処理用トレイ
KR20040023999A (ko) * 2002-09-12 2004-03-20 엘지전자 주식회사 의류건조기의 모터축 구조
US7850912B2 (en) * 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
US7648678B2 (en) 2002-12-20 2010-01-19 Dako Denmark A/S Method and system for pretreatment of tissue slides
US7584019B2 (en) 2003-12-15 2009-09-01 Dako Denmark A/S Systems and methods for the automated pre-treatment and processing of biological samples
US7875245B2 (en) * 2003-05-14 2011-01-25 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
US20060073074A1 (en) * 2004-10-06 2006-04-06 Lars Winther Enhanced sample processing system and methods of biological slide processing
US20050074890A1 (en) * 2003-05-19 2005-04-07 Ventana Medical Systems, Inc. Electrophoretic in situ tissue staining
ES2920892T3 (es) * 2003-06-12 2022-08-11 Accupath Diagnostic Laboratories Inc Método para formar matrices de células
US7642064B2 (en) 2003-06-24 2010-01-05 Ventana Medical Systems, Inc. Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest
US7767152B2 (en) 2003-08-11 2010-08-03 Sakura Finetek U.S.A., Inc. Reagent container and slide reaction retaining tray, and method of operation
US9518899B2 (en) 2003-08-11 2016-12-13 Sakura Finetek U.S.A., Inc. Automated reagent dispensing system and method of operation
US7501283B2 (en) 2003-08-11 2009-03-10 Sakura Finetek U.S.A., Inc. Fluid dispensing apparatus
US7744817B2 (en) 2003-08-11 2010-06-29 Sakura Finetek U.S.A., Inc. Manifold assembly
US7273591B2 (en) * 2003-08-12 2007-09-25 Idexx Laboratories, Inc. Slide cartridge and reagent test slides for use with a chemical analyzer, and chemical analyzer for same
AU2004271210A1 (en) * 2003-09-09 2005-03-17 Biogenex Laboratories Sample processing system
US7588733B2 (en) 2003-12-04 2009-09-15 Idexx Laboratories, Inc. Retaining clip for reagent test slides
US8012693B2 (en) * 2003-12-16 2011-09-06 3M Innovative Properties Company Analysis of chemically crosslinked cellular samples
US8026106B1 (en) 2003-12-18 2011-09-27 Ventana Medical Systems, Inc. Removal of mercuric chloride crystals from fixed tissues
EP1697719B1 (de) * 2003-12-23 2018-09-19 Ventana Medical Systems, Inc. Verfahren und vorrichtung für effiziente dünnfilmfluid-bearbeitung auf ebenen flächen
CA2556772A1 (en) * 2004-03-02 2005-09-15 Dako Denmark A/S Reagent delivery system, dispensing device and container for a biological staining apparatus
AU2005254782A1 (en) 2004-06-18 2005-12-29 Biolipox Ab Indoles useful in the treatment of inflammation
AU2005259981B2 (en) * 2004-06-29 2012-01-12 Dako Denmark A/S Method of pre-treatment and staining of and support device for a biological sample
US7867443B2 (en) 2004-07-23 2011-01-11 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
EP1771730B1 (de) * 2004-07-23 2014-08-20 Ventana Medical Systems, Inc. Verfahren und vorrichtung zum aufbringen von flüssigkeiten auf eine biologische probe
US7514041B2 (en) * 2004-07-28 2009-04-07 N-Solv Corporation Method and apparatus for testing heavy oil production processes
DE602005026867D1 (de) 2005-01-19 2011-04-21 Biolipox Ab Entzündungshemmende indol-derivate
GB0501590D0 (en) * 2005-01-25 2005-03-02 Ceres Power Ltd Processing of enhanced performance LSCF fuel cell cathode microstructure and a fuel cell cathode
CA2623241A1 (en) * 2005-04-21 2006-11-02 Celerus Diagnostics, Inc. Parallel processing fluidic method and apparatus for automated rapid immunohistochemistry
DE102005020426B4 (de) * 2005-04-29 2017-05-04 Leica Biosystems Nussloch Gmbh Eindeckautomat
WO2006127852A2 (en) * 2005-05-24 2006-11-30 Angros Lee H In situ heat induced antigen recovery and staining apparatus and method
CN100406874C (zh) * 2005-06-20 2008-07-30 北京源德生物医学工程有限公司 半自动微孔板单光子计数仪的门组件
EP1904670B1 (de) * 2005-06-28 2011-09-28 The Board of Regents of the University of Oklahoma Verfahren zur züchtung und entnahme von kohlenstoffnanoröhren
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
GB0521851D0 (en) * 2005-10-26 2005-12-07 Genial Genetic Solutions Ltd Biological apparatus
US9551635B2 (en) * 2006-03-09 2017-01-24 Biogenex Laboratories Inc. Sample processing system
US8459509B2 (en) 2006-05-25 2013-06-11 Sakura Finetek U.S.A., Inc. Fluid dispensing apparatus
CA2549614C (en) * 2006-06-07 2014-11-25 N-Solv Corporation Methods and apparatuses for sagd hydrocarbon production
CA2552482C (en) * 2006-07-19 2015-02-24 N-Solv Corporation Methods and apparatuses for enhanced in situ hydrocarbon production
US20090321263A1 (en) * 2006-09-22 2009-12-31 Fujifilm Corporation Clinical analysis apparatus
ES2663080T3 (es) 2006-11-01 2018-04-11 Ventana Medical Systems, Inc. Haptenos, conjugados de haptenos, composiciones de los mismos y método para su preparación y uso
US9116129B2 (en) 2007-05-08 2015-08-25 Idexx Laboratories, Inc. Chemical analyzer
ES2731432T3 (es) 2007-05-23 2019-11-15 Ventana Med Syst Inc Transportadores poliméricos para inmunohistoquímica e hibridación in situ
ES2435666T3 (es) * 2007-07-10 2013-12-20 Ventana Medical Systems, Inc. Aparato y método para el tratamiento de muestras biológicas
US8440425B2 (en) * 2007-12-18 2013-05-14 Abbott Laboratories Method of preparing a biological specimen slide
WO2009106081A1 (en) 2008-02-29 2009-09-03 Dako Denmark A/S Systems and methods for tracking and providing workflow information
US9802022B2 (en) * 2008-03-06 2017-10-31 Resmed Limited Humidification of respiratory gases
WO2009149013A2 (en) 2008-06-05 2009-12-10 Ventana Medical Systems, Inc. Compositions comprising nanomaterials and method for using such compositions for histochemical processes
CA2734783C (en) 2008-08-22 2016-04-19 Ventana Medical Systems, Inc. Method for chromogenic detection of two or more target molecules in a single sample
GB2477648B (en) 2008-08-29 2013-02-20 Lee H Angros In situ heat induced antigen recovery and staining apparatus and method
WO2010048631A2 (en) * 2008-10-24 2010-04-29 Biomicro, Inc. Modular system for performing laboratory protocols and associated methods
AU2009313985B2 (en) 2008-11-12 2014-07-31 Ventana Medical Systems, Inc. Methods and apparatuses for heating slides carrying specimens
AU2010253978B2 (en) 2009-05-29 2014-12-11 Ventana Medical Systems, Inc. Methods of scoring gene copy number in a biological sample using in situ hybridization
WO2010138908A1 (en) 2009-05-29 2010-12-02 Ventana Medical Systems, Inc. Igfir gene copy number as a prognostic marker in a non-small cell lung cancer
DE102010010975B4 (de) 2009-09-14 2012-05-31 Dcs Innovative Diagnostik-Systeme Dr. Christian Sartori Gmbh & Co. Kg Objektträgerhalter
USD638550S1 (en) 2009-11-13 2011-05-24 3M Innovative Properties Company Sample processing disk cover
US9498791B2 (en) 2009-11-13 2016-11-22 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
US10746752B2 (en) 2009-11-13 2020-08-18 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
USD667561S1 (en) 2009-11-13 2012-09-18 3M Innovative Properties Company Sample processing disk cover
KR101358549B1 (ko) * 2009-11-13 2014-02-05 벤타나 메디컬 시스템즈, 인코포레이티드 조절 가능한 체적 수용을 위한 박막 프로세싱 장치
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
USD638951S1 (en) 2009-11-13 2011-05-31 3M Innovative Properties Company Sample processing disk cover
US20120295279A1 (en) 2010-02-05 2012-11-22 Nichirei Biosciences Inc. Pretreatment solution for immunohistochemical staining and condensed solution thereof
EP2539466A4 (de) 2010-02-26 2013-08-07 Ventana Med Syst Inc Zytogene analyse von metaphasen-chromosomen
WO2011106583A1 (en) 2010-02-26 2011-09-01 Ventana Medical Systems, Inc. Polytag probes
US10539487B2 (en) 2010-03-04 2020-01-21 Ventana Medical Systems, Inc. Systems and methods for monitoring tissue sample processing
US10126216B2 (en) 2011-02-17 2018-11-13 Ventana Medical Systems, Inc. Method for tissue sample fixation
CA2788664C (en) 2010-03-04 2023-04-11 Ventana Medical Systems, Inc. Processing system for processing specimens using acoustic energy
EP2564203B1 (de) 2010-04-27 2017-06-07 Ventana Medical Systems, Inc. Mit antikörpern konjugierte nanopartikel, deren produktion und deren verwendung
US10697990B2 (en) 2010-04-29 2020-06-30 Leica Biosystems Richmond, Inc. Analytical system for performing laboratory protocols and associated methods
WO2011149943A1 (en) 2010-05-24 2011-12-01 Ventana Midical Systems, Inc. Method for differentiation of non-small cellung carcinoma
CN103540518B (zh) * 2010-07-23 2015-07-08 贝克曼考尔特公司 化验盒
JP5393610B2 (ja) * 2010-07-28 2014-01-22 株式会社日立ハイテクノロジーズ 核酸分析装置
DK2625502T3 (en) 2010-10-06 2018-12-17 Biocare Medical Llc Method and system for efficient processing of biological samples
BR112013014360B8 (pt) 2010-12-30 2020-12-15 Ventana Med Syst Inc método para detectar um alvo em uma amostra e kit
US20130302852A1 (en) 2011-01-10 2013-11-14 Ventana Medical Systems, Inc. Hematoxylin Staining Method
US8752732B2 (en) 2011-02-01 2014-06-17 Sakura Finetek U.S.A., Inc. Fluid dispensing system
US9945763B1 (en) 2011-02-18 2018-04-17 Biocare Medical, Llc Methods and systems for immunohistochemistry heat retrieval of biological samples
EP2686662B1 (de) 2011-02-28 2022-01-19 Agilent Technologies, Inc. Zweistufiges unmischbares system zur vorbehandlung eingebetteter biologischer proben
CN103534359B (zh) 2011-03-14 2016-07-06 文塔纳医疗系统公司 分析染色体易位的方法及其系统
USD672467S1 (en) 2011-05-18 2012-12-11 3M Innovative Properties Company Rotatable sample processing disk
ES2755078T3 (es) 2011-05-18 2020-04-21 Diasorin S P A Sistemas y métodos para medición volumétrica en un dispositivo de procesamiento de muestra
WO2012158988A1 (en) 2011-05-18 2012-11-22 3M Innovative Properties Company Systems and methods for valving on a sample processing device
ES2870874T3 (es) 2011-05-18 2021-10-27 Diasorin S P A Sistemas y métodos para detectar la presencia de un volumen seleccionado de material en un dispositivo de procesamiento de muestra
US8932543B2 (en) 2011-09-21 2015-01-13 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
US8580568B2 (en) 2011-09-21 2013-11-12 Sakura Finetek U.S.A., Inc. Traceability for automated staining system
WO2013079606A1 (en) 2011-12-01 2013-06-06 Ventana Medical Systems, Inc. Automated dual stain of mirna and protein targets
US20130171642A1 (en) 2011-12-30 2013-07-04 Ventana Medical Systems, Inc. Automated analysis of circulating tumor cells
US20130203109A1 (en) 2012-01-26 2013-08-08 Leica Biosystems Richmond, Inc. Methods and Compositions for Hematoxylin and Eosin Staining
WO2013110574A1 (en) 2012-01-27 2013-08-01 Ventana Medical Systems, Inc. Devices and methods for detecting bio-analytes using optically decipherable patterns
AU2013214345B2 (en) 2012-02-01 2016-09-15 Ventana Medical Systems, Inc. System for detecting genes in tissue samples
EP2823281B1 (de) 2012-03-09 2018-11-28 Leica Biosystems Richmond, Inc. Vorrichtung und verfahren zur regelung der temperatur in einer strömenden flüssigkeit in einem laborprobenverarbeitungssystem
WO2013139554A1 (en) 2012-03-19 2013-09-26 Ventana Medical Systems, Inc. Gram staining method with improved decolorization of the crystal violet-iodine complex from gram negative bacteria
CN104321442B (zh) * 2012-04-27 2018-06-05 塞弗德公司 具有多类处理模块的装置
AU2013329655B2 (en) 2012-10-08 2017-01-12 Ventana Medical Systems, Inc. Methods, kits, and systems for clarifying pigmented samples
WO2014074456A1 (en) 2012-11-06 2014-05-15 Biodot, Inc. Controlled printing of a cell sample for karyotyping
WO2014079802A2 (en) 2012-11-20 2014-05-30 Ventana Medical Systems, Inc. Laser ablation inductively-coupled plasma mass spectral tissue diagnostics
WO2014085854A1 (en) * 2012-12-03 2014-06-12 Leica Biosystems Melbourne Pty Ltd Thermal module for a sample processing assembly
SG11201505019WA (en) * 2012-12-26 2015-07-30 Ventana Med Syst Inc Specimen processing systems and methods for holding slides
US11274998B2 (en) 2012-12-26 2022-03-15 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
US9989448B2 (en) 2012-12-26 2018-06-05 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
CN104870974B (zh) * 2012-12-26 2017-07-18 文塔纳医疗系统公司 标本处理系统和用于制备试剂的方法
CN103149070B (zh) * 2013-03-11 2014-10-08 黄石市第一医院 一种自动染片机
USD728120S1 (en) 2013-03-15 2015-04-28 Ventana Medical Systems, Inc. Arcuate member for moving liquids along a microscope slide
US10429279B2 (en) 2013-07-28 2019-10-01 Xmd, Llc Devices and cartridges for extracting bio-sample regions and molecules of interest
JP6232138B2 (ja) 2013-12-13 2017-11-15 ベンタナ メディカル システムズ， インコーポレイテッド 生物学的試料の組織学的処理のための染色試薬および他の液体ならびに関連技術
EP4113097A1 (de) 2013-12-13 2023-01-04 Ventana Medical Systems, Inc. Automatisierte verarbeitungssysteme und verfahren zur thermischen verarbeitung von mikroskopobjektträgern
AU2014363717B2 (en) * 2013-12-13 2016-12-22 Ventana Medical Systems, Inc. Automated histological processing of biological specimens and associated technology
EP3080577B1 (de) 2013-12-13 2021-07-28 Ventana Medical Systems, Inc. Wärmeverwaltung im kontext der automatisierten histologischen verarbeitung biologischer proben und entsprechende technologie
WO2015106008A1 (en) 2014-01-10 2015-07-16 Idexx Laboratories, Inc. Chemical analyzer
WO2015124703A1 (en) 2014-02-24 2015-08-27 Ventana Medical Systems, Inc. Quinone methide analog signal amplification
JP6825915B2 (ja) 2014-02-24 2021-02-03 ヴェンタナ メディカル システムズ， インク． 標識された２’−ｏ−メチルｒｎａオリゴヌクレオチドプローブ及びシグナル増幅系を使用する自動ｒｎａ検出
DK3152577T3 (en) 2014-06-06 2018-10-01 Ventana Med Syst Inc SIGNIFICANCE OF INTRATUMORAL HER2 HETEROGENITY IN BREAST CANCER AND APPLICATIONS HEFAR
EP3160648B1 (de) 2014-06-30 2024-04-03 Ventana Medical Systems, Inc. Probenverarbeitungssysteme, pipettenanordnungen und verfahren zur zubereitung von reagenzien
CA2957783C (en) 2014-10-02 2023-02-28 Ventana Medical Systems, Inc. Polymers and conjugates comprising the same
CN107111874B (zh) 2014-12-30 2022-04-08 文塔纳医疗系统公司 用于共表达分析的系统和方法
JP6908531B2 (ja) 2015-01-27 2021-07-28 ベンタナ メディカル システムズ， インコーポレイテッド アルデヒドに基づく固定溶液における長時間浸漬を用いる、組織試料固定法
EP3251087B1 (de) 2015-01-29 2018-11-28 Ventana Medical Systems, Inc. Punkterkennung, farbklassifizierung von punkten und zählung von farbklassifizierten punkten
WO2016120442A1 (en) 2015-01-30 2016-08-04 Ventana Medical Systems, Inc. Foreground segmentation and nucleus ranking for scoring dual ish images
WO2016120441A2 (en) 2015-01-30 2016-08-04 Ventana Medical Systems, Inc. Quality metrics for automatic evaluation of dual ish images
WO2016146616A1 (en) 2015-03-16 2016-09-22 Ventana Medical Systems, Inc. Control slides for immunohistochemistry generated from three-dimensional cell line cultures
ES2939352T3 (es) * 2015-04-13 2023-04-21 Ventana Med Syst Inc Procedimientos y sistemas de inactivación de anticuerpo con base termoquímica
CA2984701C (en) 2015-05-10 2023-09-26 Ventana Medical Systems, Inc. Compositions and methods for simultaneous inactivation of alkaline phosphatase and peroxidase enzymes during automated multiplex tissue staining assays
WO2016189065A1 (en) 2015-05-26 2016-12-01 Ventana Medical Systems, Inc. Method and system for assessing stain quality for in-situ hybridization and immunohistochemistry
CN107923915B (zh) 2015-08-28 2021-05-04 文塔纳医疗系统公司 使用经掩蔽的半抗原在福尔马林固定石蜡包埋的组织中的蛋白质邻近测定
CN105400692B (zh) * 2015-12-15 2017-06-27 上海海洋大学 等温核酸扩增装置及等温核酸扩增实验方法
CN105400693B (zh) * 2015-12-15 2017-06-06 上海海洋大学 平板等温核酸扩增芯片
WO2017132276A1 (en) 2016-01-26 2017-08-03 Ventana Medical Systems, Inc. Predictive diagnostic workflow for tumors usnig automated dissection, next generation sequencing, and automated slide stainers
WO2017155996A1 (en) 2016-03-08 2017-09-14 Ventana Medical Systems, Inc. Multiplexed immunohistochemistry using recombinant antibodies with epitope tags
US11460383B2 (en) 2016-06-16 2022-10-04 Nanocytomics, LLC Automated staining system
JP7128121B2 (ja) 2016-06-28 2022-08-30 ヴェンタナ メディカル システムズ， インク． Ｉｈｃ及びｉｓｈアッセイにおけるシグナル増幅のためのクリックケミストリーの応用
WO2018002015A1 (en) 2016-06-28 2018-01-04 Ventana Medical Systems, Inc. New colors for chromogenic ihc and ish staining with multi-dye quinone methide and tyramide conjugates
WO2018044280A1 (en) * 2016-08-30 2018-03-08 Qdaisat Sadeem Z S Automated slide dropping system
WO2018055014A1 (en) 2016-09-23 2018-03-29 Ventana Medical Systems, Inc. Methods and systems for scoring extracellular matrix biomarkers in tumor samples
CN106370830A (zh) * 2016-11-14 2017-02-01 漯河医学高等专科学校 一种具有单独滑片加热器的分子病理学装置
EP3555634B1 (de) 2016-12-16 2023-09-06 Ventana Medical Systems, Inc. Reduzierung von pipettenrückständen
ES2869903T3 (es) 2016-12-19 2021-10-26 Ventana Med Syst Inc Sistema pasivo accionado por gravedad para el tratamiento de un efluente en un sistema de diagnóstico
WO2018118759A1 (en) 2016-12-19 2018-06-28 Ventana Medical Systems, Inc. Peptide nucleic acid conjugates
CN110337588B (zh) 2016-12-19 2023-02-17 文塔纳医疗系统公司 用于定量免疫组织化学的方法和系统
CN110073222A (zh) 2016-12-21 2019-07-30 文塔纳医疗系统公司 用于试剂递送的方法、系统和固体组合物
EP3559902A1 (de) 2016-12-22 2019-10-30 Ventana Medical Systems, Inc. Computerwertung auf der basis von primärfärbung und immunhistochemischen bildern
EP3559271A1 (de) 2016-12-22 2019-10-30 Ventana Medical Systems, Inc. Vollautomatisches nukleinsäureextraktionsverfahren für gewebeproben
JP7193466B2 (ja) * 2017-01-19 2022-12-20 アジレント・テクノロジーズ・インク 複数温度光学分光計モジュール、システム、及びそれを使用する方法
JP2020510196A (ja) * 2017-03-16 2020-04-02 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． 診断分析装置におけるインキュベーションシステムの温度制御のためのシステム及び方法
WO2018189039A1 (en) 2017-04-14 2018-10-18 Ventana Medical Systems, Inc. Local tile-based registration and global placement for stitching
JP6940626B2 (ja) 2017-05-10 2021-09-29 ヴェンタナ メディカル システムズ， インク． ｐＨ調整を利用する安定化した２パートヘマトキシリン溶液
CN110637222A (zh) 2017-05-26 2019-12-31 文塔纳医疗系统公司 非接触式、在载玻片上的流体混合
WO2019002281A1 (en) 2017-06-28 2019-01-03 Ventana Medical Systems, Inc. CALIBRATION OF SYSTEM LEVEL
WO2019020556A1 (en) 2017-07-24 2019-01-31 Ventana Medical Systems, Inc. METHODS AND SYSTEMS FOR ASSESSING INFILTRAT OF IMMUNE CELLS IN TUMOR SAMPLES
EP4300424A3 (de) 2017-08-04 2024-03-06 Ventana Medical Systems, Inc. Automatische assay-beurteilung und normalisierung für bildverarbeitung
JP7216707B2 (ja) 2017-08-04 2023-02-01 ベンタナ メディカル システムズ， インコーポレイテッド 散乱補正を用いた色分離
CN111356912B (zh) 2017-11-21 2023-09-05 文塔纳医疗系统公司 使用调制气体射流的非接触式混合
JP7231631B2 (ja) 2017-12-05 2023-03-01 ベンタナ メディカル システムズ， インコーポレイテッド 腫瘍空間異質性およびインターマーカ異質性の計算方法
EP3721372A1 (de) 2017-12-06 2020-10-14 Ventana Medical Systems, Inc. Verfahren zum speichern und abrufen von digitalen pathologieanalyseergebnissen
JP7250793B2 (ja) 2017-12-07 2023-04-03 ベンタナ メディカル システムズ， インコーポレイテッド 生体画像における連帯的細胞および領域分類のための深層学習システムならびに方法
CN111491667A (zh) 2017-12-18 2020-08-04 文塔纳医疗系统公司 肽核酸缀合物
EP3729369A2 (de) 2017-12-24 2020-10-28 Ventana Medical Systems, Inc. Rechnerischer pathologieansatz zur retrospektiven analyse von auf gewebe basierenden begleitdiagnostischen klinischen studien
WO2019122057A2 (en) 2017-12-24 2019-06-27 Ventana Medical Systems, Inc. Eosin staining techniques
CN111492225A (zh) 2017-12-24 2020-08-04 文塔纳医疗系统公司 无酚抗酸染色组合物及其用途
WO2019137980A1 (en) 2018-01-11 2019-07-18 Ventana Medical Systems, Inc. Anti-fogging barcode reader
WO2019149817A1 (en) 2018-01-31 2019-08-08 Ventana Medical Systems, Inc. Methods and systems for evaluation of immune cell infiltrate in stage iii colorectal cancer
WO2019197509A1 (en) 2018-04-13 2019-10-17 Ventana Medical Systems, Inc. Systems for cell shape estimation
EP3794548A1 (de) 2018-05-15 2021-03-24 Ventana Medical Systems, Inc. Quantifizierung des signals in fleckenaggregaten
WO2019224153A1 (en) 2018-05-21 2019-11-28 Genentech, Inc. Her2 heterogeneity as a biomarker in cancer
EP3824288A1 (de) 2018-07-17 2021-05-26 Ventana Medical Systems, Inc. Materialien und verfahren zur detektion von fusionsproteinen
JP2021531790A (ja) 2018-07-27 2021-11-25 ベンタナ メディカル システムズ， インコーポレイテッド 自動化された原位置ハイブリッド形成分析のためのシステム
CN112839710A (zh) 2018-08-09 2021-05-25 霍夫曼-拉罗奇有限公司 帕金森氏病的确定
WO2020053376A1 (en) 2018-09-13 2020-03-19 Ventana Medical Systems, Inc. Histochemical and cytochemical methods for detecting ntrk fusion proteins
WO2020058339A1 (en) 2018-09-20 2020-03-26 Ventana Medical Systems, Inc. Coumarin-based crosslinking reagents
CN112789684A (zh) 2018-10-01 2021-05-11 文塔纳医疗系统公司 用于预测对pd-1轴导向疗法的应答的方法和系统
WO2020081343A1 (en) 2018-10-15 2020-04-23 Ventana Medical Systems, Inc. Systems and methods for cell classification
CN112823376A (zh) 2018-10-15 2021-05-18 文塔纳医疗系统公司 图像增强以实现改善的核检测和分割
EP3884259A1 (de) 2018-11-20 2021-09-29 Ventana Medical Systems, Inc. Verfahren und systeme zur herstellung und analyse von zellulären proben für morphologische merkmale und biomarkerexpression
JP7411667B2 (ja) 2019-02-05 2024-01-11 ヴェンタナ メディカル システムズ， インク． ステージｉｖの結腸直腸がんにおける免疫細胞浸潤の評価のための方法及びシステム
JP2022533577A (ja) 2019-05-14 2022-07-25 ヴェンタナ メディカル システムズ， インク． 生物学的試料処理チャンバを含むシステム
JP2022546058A (ja) 2019-08-28 2022-11-02 ベンタナ メディカル システムズ， インコーポレイテッド 振動分光法を使用して検体固定の持続時間および品質を評価するためのシステムおよび方法
CN114303203A (zh) 2019-08-28 2022-04-08 文塔纳医疗系统公司 使用振动光谱法评估抗原修复和靶标修复进展定量
WO2021173674A1 (en) 2020-02-26 2021-09-02 A2 Biotherapeutics, Inc. Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof
WO2021180108A1 (en) * 2020-03-11 2021-09-16 Guizhou Meixinda Medical Technologies Co., Ltd. Devices and components for automated tissue processing and staining and uses thereof
CN114207403B (zh) * 2020-03-11 2022-11-22 贵州美鑫达医疗科技有限公司 用于自动组织处理和染色的装置和组件及其使用
WO2021186902A1 (ja) * 2020-03-17 2021-09-23 株式会社日立ハイテク 自動分析装置
CN115552248A (zh) 2020-05-07 2022-12-30 文塔纳医疗系统公司 用于评价肿瘤样品中egfr和egfr配体表达的组织化学系统和方法
WO2021224361A2 (en) 2020-05-08 2021-11-11 Ventana Medical Systems, Inc. Semi-synthesis and use of racemic hematoxylin
CN116710131A (zh) 2020-09-22 2023-09-05 文塔纳医疗系统公司 使用表皮调节素和双调蛋白来预测对表皮生长因子受体定向疗法的反应
CN112799444A (zh) * 2020-12-27 2021-05-14 北京工业大学 一种基于51单片机的血液寄生虫检测温控加热仪
WO2022152777A1 (en) 2021-01-15 2022-07-21 F. Hoffmann-La Roche Ag Storage stable caged haptens
CN116868054A (zh) 2021-01-25 2023-10-10 文塔纳医疗系统公司 包括用一个或多个可检测部分标记的一种或多种生物标志物的染色生物学样本
WO2022223137A1 (en) 2021-04-18 2022-10-27 Ventana Medical Systems, Inc. Morphological marker staining
KR20230091463A (ko) * 2021-12-16 2023-06-23 (주)레보스케치 회전형 다채널 형광스캐너
WO2023147252A1 (en) 2022-01-25 2023-08-03 Ventana Medical Systems, Inc. Materials and methods for bleaching melanin-pigmented tissues
WO2023192946A1 (en) 2022-03-31 2023-10-05 Ventana Medical Systems, Inc. Methods and systems for predicting response to pd-1 axis directed therapeutics in colorectal tumors with deficient mismatch repair
WO2023239529A2 (en) 2022-06-09 2023-12-14 Ventana Medical Systems, Inc. On-slide synthesis of a schiff reagent

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE373963B (de) 1973-06-14 1975-02-17 Janson Sven Olof
GB1445389A (en) * 1973-10-16 1976-08-11 Chemlab Mfg Ltd Sampling arrangements
US3853092A (en) 1973-10-25 1974-12-10 Corning Glass Works Apparatus for nutating and staining a microscope slide
US4043292A (en) * 1975-07-21 1977-08-23 Corning Glass Works Microscope slide staining apparatus having temperature control
US4092952A (en) 1977-08-19 1978-06-06 Wilkie Ronald N Automatic slide stainer
SE7801564L (sv) 1978-02-10 1979-08-11 Lkb Produkter Ab Anordning for infergning av biologiska preparat
DE2915248C3 (de) 1979-04-14 1982-01-14 Gise, Frhr. von, Hardo, Dr.med., 7400 Tübingen Einrichtung zum automatischen wahlweisen u. exakten Behandeln von Präparaten
AT364439B (de) * 1980-02-12 1981-10-27 List Hans Einrichtung zur anordnung an einer probeneingabeoeffnung eines analysengeraetes
US4647431A (en) 1980-05-31 1987-03-03 Fuji Photo Film Co., Ltd. Device for maintaining a constant temperature for chemical analysis
US4384193A (en) * 1981-06-09 1983-05-17 Immulok, Inc. Incubating device for specimen mounted on glass slides in immunoassays
US4430299A (en) 1981-06-18 1984-02-07 Coulter Electronics, Inc. Apparatus for monitoring chemical reactions
DK536881A (da) * 1981-12-04 1983-06-05 Radiometer As Proevebaeger
SE451164B (sv) * 1982-03-22 1987-09-07 Erik Ohlin Apparat och sett for serieutspedning av en provvetska
AT381794B (de) * 1984-02-02 1986-11-25 Avl Verbrennungskraft Messtech Analysengeraet zur messung fluessiger oder gasfoermiger proben
US4629862A (en) 1984-03-28 1986-12-16 Olympus Optical Company Ltd. Sample heater for use in microscopes
US4644807A (en) * 1985-02-21 1987-02-24 Dionex Corporation Fluid sample delivery apparatus
US4731335A (en) 1985-09-13 1988-03-15 Fisher Scientific Company Method for treating thin samples on a surface employing capillary flow
JPH0640054B2 (ja) * 1985-09-20 1994-05-25 株式会社千代田製作所 電子顕微鏡標本作成用包埋装置
US4695430A (en) 1985-10-31 1987-09-22 Bio/Data Corporation Analytical apparatus
US4858155A (en) 1985-12-24 1989-08-15 Beckman Instruments, Inc. Reaction temperature control system
US4933146A (en) 1986-07-11 1990-06-12 Beckman Instruments, Inc. Temperature control apparatus for automated clinical analyzer
US4888998A (en) * 1986-07-11 1989-12-26 Beckman Instruments, Inc. Sample handling system
DE3773562D1 (de) * 1986-07-11 1991-11-14 Beckman Instruments Inc Probenhandhabungsvorrichtung.
US5154889A (en) 1986-08-07 1992-10-13 Fuji Photo Film Co., Ltd. Chemical analysis apparatus
US4721680A (en) * 1986-08-11 1988-01-26 Multi-Technology, Inc. Methods of using micro pipette tips
FR2606885B1 (fr) * 1986-11-14 1989-08-04 Abx Sarl Dispositif de nettoyage d'une aiguille de prelevement d'un liquide
US4847208A (en) 1987-07-29 1989-07-11 Bogen Steven A Apparatus for immunohistochemical staining and method of rinsing a plurality of slides
GB8722902D0 (en) 1987-09-30 1987-11-04 Shandon Southern Prod Tissue &c processing
US4927765A (en) * 1988-02-29 1990-05-22 Pharmacia Eni Diagnostics, Inc. Automatic reagent dispenser
FI80147C (fi) * 1988-04-15 1990-04-10 Kone Oy Foerfarande foer foerverkligande av val av vaetska vid vaetskedosering i en analysator samt provtagningsanordning.
US5597733A (en) 1988-07-25 1997-01-28 Precision Systems, Inc. Automatic multiple-sample multiple-reagent dispensing method in chemical analyzer
JPH0718785B2 (ja) * 1988-09-19 1995-03-06 株式会社日立製作所 フローセル装置
US4865986A (en) 1988-10-06 1989-09-12 Coy Corporation Temperature control apparatus
US4962041A (en) * 1988-10-06 1990-10-09 Medical Automation Specialities, Inc. Method and apparatus for automatic processing and analyzing of blood serum
FR2641436A1 (de) 1988-12-30 1990-07-06 Labo Electronique Physique
US5429803A (en) * 1991-04-18 1995-07-04 Lamina, Inc. Liquid specimen container and attachable testing modules
US5264182A (en) * 1989-04-12 1993-11-23 Olympus Optical Co., Ltd. Sample and reagent delivery device with a probe and probe supporting member for preventing contamination
US5093557A (en) 1989-05-16 1992-03-03 Microscience, Inc. Substrate heater and heating element
CA2017111C (en) * 1989-06-01 1995-10-31 Andreas Greter Pipetting insert
FR2649018B1 (fr) * 1989-06-30 1991-09-13 Degremont Dispositif pour l'introduction d'un liquide dans un milieu constitue par un materiau granulaire, en vue de la fluidisation de ce materiau
GB8919145D0 (en) 1989-08-23 1989-10-04 Royal Postgrad Med School Apparatus for the in situ hybridisation of slide-mounted cell samples
US5089229A (en) 1989-11-22 1992-02-18 Vettest S.A. Chemical analyzer
US4989623A (en) * 1989-12-01 1991-02-05 Akzo N.V. Apparatus and method for cleaning reagent delivery probes
CA2035067C (en) * 1990-02-22 1995-06-27 William M. Blough, Jr. Fluid mixing device
JPH05506096A (ja) 1990-03-02 1993-09-02 テクマー　カンパニー 分析装置の移送装置
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US5075079A (en) * 1990-05-21 1991-12-24 Technicon Instruments Corporation Slide analysis system
US5207987A (en) 1990-05-21 1993-05-04 Pb Diagnostic Systems Inc. Temperature controlled chamber for diagnostic analyzer
US5425918A (en) 1990-07-18 1995-06-20 Australian Biomedical Corporation Apparatus for automatic tissue staining for immunohistochemistry
JP2530738Y2 (ja) * 1990-11-13 1997-03-26 株式会社明電舎 ノズル洗浄ポート
KR100236506B1 (ko) 1990-11-29 2000-01-15 퍼킨-엘머시터스인스트루먼츠 폴리머라제 연쇄 반응 수행 장치
DE69130205T2 (de) 1990-12-25 1999-03-25 Ngk Insulators Ltd Heizungsapparat für eine Halbleiterscheibe und Verfahren zum Herstellen desselben
US5273905A (en) 1991-02-22 1993-12-28 Amoco Corporation Processing of slide mounted material
US5246665A (en) 1991-06-03 1993-09-21 Abbott Laboratories Heat and air flow control for assay carrier
CA2218875C (en) * 1991-07-23 2000-11-07 The Research Foundation Of State University Of New York Improvements in the in situ pcr
GB9123463D0 (en) 1991-11-05 1991-12-18 Hybaid Ltd Reaction temperature control device
FI915731A0 (fi) 1991-12-05 1991-12-05 Derek Henry Potter Foerfarande och anordning foer reglering av temperaturen i ett flertal prov.
FR2688313A1 (fr) * 1992-03-04 1993-09-10 Marteau D Autry Eric Filtration et identification automatique d'echantillons.
US5947167A (en) * 1992-05-11 1999-09-07 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps
US5316452A (en) 1992-05-11 1994-05-31 Gilbert Corporation Dispensing assembly with interchangeable cartridge pumps
US5645114A (en) * 1992-05-11 1997-07-08 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps
US5314825A (en) * 1992-07-16 1994-05-24 Schiapparelli Biosystems, Inc. Chemical analyzer
US5601141A (en) * 1992-10-13 1997-02-11 Intelligent Automation Systems, Inc. High throughput thermal cycler
US5408891A (en) 1992-12-17 1995-04-25 Beckman Instruments, Inc. Fluid probe washing apparatus and method
US5364790A (en) * 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
JP3323294B2 (ja) * 1993-09-14 2002-09-09 富士写真フイルム株式会社 点着チップおよびこの点着チップを用いた液体濃縮防止方法
US5439649A (en) 1993-09-29 1995-08-08 Biogenex Laboratories Automated staining apparatus
JP3051626B2 (ja) 1993-12-09 2000-06-12 富士写真フイルム株式会社 インキュベータ
US5523056A (en) 1994-04-29 1996-06-04 Johnson & Johnson Clinical Diagnostics, Inc. Twin rotor incubator assembly
JP3387649B2 (ja) 1994-09-16 2003-03-17 富士写真フイルム株式会社 点着チップ
EP0729021A1 (de) * 1995-02-25 1996-08-28 Roche Diagnostics GmbH Vorrichtung zur Bearbeitung von Proben auf Objektträgern
US5645144A (en) * 1995-08-22 1997-07-08 A-Dec, Inc. Control mechanism for sliding panel
EP0835452B1 (de) * 1996-04-26 2005-08-10 Dade Behring Inc. Verfahren und vorrichtung zur vorbehandlung von proben in einem chemischen analysator
US6183693B1 (en) 1998-02-27 2001-02-06 Cytologix Corporation Random access slide stainer with independent slide heating regulation
US6096271A (en) * 1998-02-27 2000-08-01 Cytologix Corporation Random access slide stainer with liquid waste segregation
US7009471B2 (en) * 2002-12-09 2006-03-07 Corridor Systems, Inc. Method and apparatus for launching a surfacewave onto a single conductor transmission line using a slohed flared cone
US20100128351A1 (en) * 2008-11-21 2010-05-27 3M Innovative Properties Company Curved sided cone structures for controlling gain and viewing angle in an optical film

Also Published As

Publication number Publication date
CA2321836C (en) 2004-09-28
JP4505547B2 (ja) 2010-07-21
JP2006304806A (ja) 2006-11-09
AU2879699A (en) 1999-09-15
CN1297529A (zh) 2001-05-30
JP2009216714A (ja) 2009-09-24
ES2354598T3 (es) 2011-03-16
AU2003255169A1 (en) 2003-11-13
AU2883499A (en) 1999-09-15
CA2321836A1 (en) 1999-09-02
JP4091960B2 (ja) 2008-05-28
CA2320750A1 (en) 1999-09-02
AU763354B2 (en) 2003-07-17
CA2320750C (en) 2004-08-24
EP1073892A4 (de) 2005-10-12
JP2002505089A (ja) 2002-02-19
ATE489613T1 (de) 2010-12-15
US6296809B1 (en) 2001-10-02
CN100403008C (zh) 2008-07-16
WO1999044030A1 (en) 1999-09-02
WO1999043434A1 (en) 1999-09-02
JP3847559B2 (ja) 2006-11-22
EP1056541A1 (de) 2000-12-06
EP1056541B1 (de) 2017-10-25
EP1056541A4 (de) 2005-11-30
EP2284543A2 (de) 2011-02-16
JP2010091579A (ja) 2010-04-22
EP2284543A3 (de) 2015-05-27
WO1999044030A9 (en) 1999-12-16
JP2002504694A (ja) 2002-02-12
EP1073892B1 (de) 2010-11-24
JP4505538B2 (ja) 2010-07-21
EP1073892A1 (de) 2001-02-07

Similar Documents

Publication Publication Date Title
DE69942975D1 (de) Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern
JP3256818B2 (ja) 試料液体分析装置及び試料液体分析法
CA1081994A (en) Liquid dispenser with improved aspirating probe
US5079959A (en) Analyzing system using sheath flow of sample
FI922477A (fi) Anordning och foerfarande foer rengoering av matningssonder foer reagens.
US20100051060A1 (en) Nozzle cleaning method, nozzle cleaning device, and automatic analyzer
CA2321739A1 (en) Random access slide stainer with liquid waste segregation
JPS62118258A (ja) 自動分析装置
EP1450163A3 (de) Spritze mit Vermeidung der Blasenbildung
DK160730B (da) Kontinuert stroemningsanlaeg for vaesker
DE68928695T2 (de) Saug- und spendevorrichtung für flüssigmuster
JPH05307043A (ja) 分取用チップの使用モードが選択可能な分注装置
ATE274925T1 (de) Ausgabevorrichtung
US4179932A (en) Supply apparatus
CN212008321U (zh) 一种一体化多功能快速检测设备
WO1996008725A1 (en) Method for analysis and device for carrying out the method
US4471297A (en) Multi-sample particle analysis apparatus and method
DE59804407D1 (de) Einrichtung zum Dosieren einer Beschichtungsflüssigkeit für Bedruckstoffe in einer Druckmaschine
ATE113927T1 (de) Vorrichtung zum befüllen von underdruckfesten behältern mit flüssigkeiten.
JPH06213906A (ja) 自動試薬ノズル洗浄機構
JPS5654357A (en) Dispensing method
ATE275361T1 (de) Behälter versehen mit einem durchflussmesser zur dosierung von regenerationsflüssigkeit in einer spülmaschine
JPS62167482A (ja) 多項目自動分析装置の制御方法
JPH0316060Y2 (de)
JPH025415Y2 (de)