EP2177895A3 - Method and apparatus for detection of multiple analytes - Google Patents

Method and apparatus for detection of multiple analytes Download PDF

Info

Publication number
EP2177895A3
EP2177895A3 EP10150414A EP10150414A EP2177895A3 EP 2177895 A3 EP2177895 A3 EP 2177895A3 EP 10150414 A EP10150414 A EP 10150414A EP 10150414 A EP10150414 A EP 10150414A EP 2177895 A3 EP2177895 A3 EP 2177895A3
Authority
EP
European Patent Office
Prior art keywords
analyte
fluid
sample
patient
analyze
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10150414A
Other languages
German (de)
French (fr)
Other versions
EP2177895A2 (en
Inventor
B. Bernhard
W. Dale Hall
David N. Callicoat
Jennifer H. Gable
James R. Braig
Kenneth G. Witte
Mark Wechsler
Peng Zheng
Peter Rule
Richard Keenan
Richard A. King
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Optiscan Biomedical Corp
Original Assignee
Optiscan Biomedical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optiscan Biomedical Corp filed Critical Optiscan Biomedical Corp
Priority to EP10185762A priority Critical patent/EP2302357A1/en
Publication of EP2177895A2 publication Critical patent/EP2177895A2/en
Publication of EP2177895A3 publication Critical patent/EP2177895A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14557—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted to extracorporeal circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1495—Calibrating or testing of in-vivo probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150213—Venting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221—Valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229—Pumps for assisting the blood sampling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150847—Communication to or from blood sampling device
    • A61B5/150862—Communication to or from blood sampling device intermediate range, e.g. within room or building
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150992—Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/155—Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/201—Glucose concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14232—Roller pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light

Abstract

Disclosed is an apparatus for analyzing the composition of bodily fluid, the apparatus comprising a fluid handling network (10) including a patient end (12) configured to maintain fluid communication with a bodily fluid in a patient and at least one pump (203) intermittently operable to draw a sample (S) of bodily fluid from the patient; and a fluid analyzer (334) positioned to analyze at least a portion of the sample (S), wherein the fluid analyzer (334) is configured to (a) obtain a spectroscopic analysis measurement of at least the portion of the sample (S); (b) analyze the measurement to identify a possible interferent to an analyte, the spectroscopic features of the analyte overlapping with the spectroscopic features of the possible interferent; (c) generate a model for estimating the concentration of the analyte; and (d) estimate a concentration of the analyte in the at least the portion of the sample (S) using the model.
EP10150414A 2005-02-14 2006-02-13 Method and apparatus for detection of multiple analytes Withdrawn EP2177895A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10185762A EP2302357A1 (en) 2005-02-14 2006-02-13 Method and apparatus for detection of multiple analytes

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US65266005P 2005-02-14 2005-02-14
US65800105P 2005-03-02 2005-03-02
US67355105P 2005-04-21 2005-04-21
US72419905P 2005-10-06 2005-10-06
US11/314,803 US20070103678A1 (en) 2005-02-14 2005-12-21 Analyte detection system with interferent identification and correction
US11/314,173 US7722537B2 (en) 2005-02-14 2005-12-21 Method and apparatus for detection of multiple analytes
US11/314,161 US20060200070A1 (en) 2005-02-14 2005-12-21 Method and apparatus for calibrating an analyte detection system with a calibration sample
US11/314,176 US8140140B2 (en) 2005-02-14 2005-12-21 Analyte detection system for multiple analytes
EP06734940A EP1853165B1 (en) 2005-02-14 2006-02-13 Apparatus for detection of multiple analytes

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP06734940.7 Division 2006-02-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP10185762.1 Division-Into 2010-10-01

Publications (2)

Publication Number Publication Date
EP2177895A2 EP2177895A2 (en) 2010-04-21
EP2177895A3 true EP2177895A3 (en) 2010-12-15

Family

ID=36571925

Family Applications (3)

Application Number Title Priority Date Filing Date
EP10185762A Withdrawn EP2302357A1 (en) 2005-02-14 2006-02-13 Method and apparatus for detection of multiple analytes
EP06734940A Not-in-force EP1853165B1 (en) 2005-02-14 2006-02-13 Apparatus for detection of multiple analytes
EP10150414A Withdrawn EP2177895A3 (en) 2005-02-14 2006-02-13 Method and apparatus for detection of multiple analytes

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP10185762A Withdrawn EP2302357A1 (en) 2005-02-14 2006-02-13 Method and apparatus for detection of multiple analytes
EP06734940A Not-in-force EP1853165B1 (en) 2005-02-14 2006-02-13 Apparatus for detection of multiple analytes

Country Status (8)

Country Link
US (5) US20070103678A1 (en)
EP (3) EP2302357A1 (en)
JP (1) JP2008530562A (en)
AT (1) ATE497361T1 (en)
AU (1) AU2006214523B2 (en)
CA (2) CA2597618C (en)
DE (1) DE602006019947D1 (en)
WO (1) WO2006088792A2 (en)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989891B2 (en) 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
EP1620004A2 (en) * 2003-04-15 2006-02-01 Optiscan Biomedical Corporation Dual measurement analyte detection system
AU2004230531A1 (en) * 2003-04-15 2004-10-28 Optiscan Biomedical Corporation Sample element qualification
US7271912B2 (en) * 2003-04-15 2007-09-18 Optiscan Biomedical Corporation Method of determining analyte concentration in a sample using infrared transmission data
AU2005299929A1 (en) * 2004-10-21 2006-05-04 Optiscan Biomedical Corporation Method and apparatus for determining an analyte concentration in a sample having interferents
US7785258B2 (en) * 2005-10-06 2010-08-31 Optiscan Biomedical Corporation System and method for determining a treatment dose for a patient
US20060189926A1 (en) * 2005-02-14 2006-08-24 Hall W D Apparatus and methods for analyzing body fluid samples
US8936755B2 (en) 2005-03-02 2015-01-20 Optiscan Biomedical Corporation Bodily fluid composition analyzer with disposable cassette
US20070081626A1 (en) * 2005-02-14 2007-04-12 Peter Rule Method and apparatus for enhancing accuracy of an analyte detection system
US20060189925A1 (en) 2005-02-14 2006-08-24 Gable Jennifer H Methods and apparatus for extracting and analyzing a component of a bodily fluid
US8251907B2 (en) 2005-02-14 2012-08-28 Optiscan Biomedical Corporation System and method for determining a treatment dose for a patient
US20070103678A1 (en) * 2005-02-14 2007-05-10 Sterling Bernhard B Analyte detection system with interferent identification and correction
US8323194B2 (en) * 2009-12-18 2012-12-04 Inlight Solutions, Inc. Detection of bubbles during hemodynamic monitoring when performing automated measurement of blood constituents
US20080161723A1 (en) * 2006-09-06 2008-07-03 Optiscan Biomedical Corporation Infusion flow interruption method and apparatus
US20080077074A1 (en) * 2006-08-15 2008-03-27 Richard Keenan Method of analyzing the composition of bodily fluids
US9561001B2 (en) 2005-10-06 2017-02-07 Optiscan Biomedical Corporation Fluid handling cassette system for body fluid analyzer
US20070179436A1 (en) * 2005-12-21 2007-08-02 Braig James R Analyte detection system with periodic sample draw and laboratory-grade analyzer
US7367942B2 (en) * 2006-02-02 2008-05-06 Palco Labs, Inc. Method and apparatus for testing blood glucose in a reversible infusion line
WO2007120746A2 (en) * 2006-04-11 2007-10-25 Optiscan Biomedical Corporation Anti-clotting apparatus and methods for fluid handling system
WO2009008892A1 (en) * 2006-08-15 2009-01-15 Optiscan Biomedical Corporation Accurate and timely body fluid analysis
US20080154184A1 (en) * 2006-12-20 2008-06-26 Blight David D Arthroscopic irrigation/aspiration pump system with declogging feature
EP1953527B2 (en) 2007-02-01 2024-01-03 Sysmex Corporation Sample analyzer and computer program product
EP1987762A1 (en) * 2007-05-03 2008-11-05 F.Hoffmann-La Roche Ag Oximeter
EP2152148A2 (en) * 2007-05-07 2010-02-17 Medingo Ltd. Reciprocating delivery of fluids to the body with analyte concentration monitoring
US8412293B2 (en) * 2007-07-16 2013-04-02 Optiscan Biomedical Corporation Systems and methods for determining physiological parameters using measured analyte values
US20090160656A1 (en) * 2007-10-11 2009-06-25 Mahesh Seetharaman Analyte monitoring system alarms
US20090156911A1 (en) * 2007-10-08 2009-06-18 Optiscan Biomedical Corporation Low draw volume analyte detection systems
WO2008144575A2 (en) 2007-05-18 2008-11-27 Optiscan Biomedical Corporation Fluid injection and safety system
US8597190B2 (en) 2007-05-18 2013-12-03 Optiscan Biomedical Corporation Monitoring systems and methods with fast initialization
US8417311B2 (en) 2008-09-12 2013-04-09 Optiscan Biomedical Corporation Fluid component analysis system and method for glucose monitoring and control
US20090018483A1 (en) * 2007-07-13 2009-01-15 Walker Stephen D Infrared Sample Chamber
US20090018416A1 (en) * 2007-07-13 2009-01-15 Walker Stephen D Analyte Concentration Measurement Device
US20090047177A1 (en) * 2007-08-17 2009-02-19 Walker Stephen D Lactate concentration measurement device
US8628311B2 (en) * 2007-09-11 2014-01-14 Boston Scientific Scimed, Inc. Thermal ablation system with dispensable therapeutic agent
EP2695573B1 (en) * 2007-10-10 2021-04-28 Optiscan Biomedical Corporation Fluid component analysis system and method for glucose monitoring and control
US8763892B2 (en) * 2007-12-31 2014-07-01 Oridon Medical 1987 Ltd. Tube verifier
US7835005B2 (en) * 2008-02-21 2010-11-16 Thermo Fisher Scientific Inc. Gas analyzer system
US8523797B2 (en) * 2008-05-08 2013-09-03 Hospira, Inc. Automated point-of-care fluid testing device and method of using the same
ES2715633T3 (en) 2008-05-20 2019-06-05 Univ Health Network Device and method for imaging and fluorescence monitoring
US7959598B2 (en) 2008-08-20 2011-06-14 Asante Solutions, Inc. Infusion pump systems and methods
EP3881874A1 (en) * 2008-09-15 2021-09-22 DEKA Products Limited Partnership Systems and methods for fluid delivery
WO2011011462A1 (en) * 2009-07-20 2011-01-27 Optiscan Biomedical Corporation Adjustable connector and dead space reduction
US10475529B2 (en) 2011-07-19 2019-11-12 Optiscan Biomedical Corporation Method and apparatus for analyte measurements using calibration sets
US9091676B2 (en) 2010-06-09 2015-07-28 Optiscan Biomedical Corp. Systems and methods for measuring multiple analytes in a sample
US9554742B2 (en) 2009-07-20 2017-01-31 Optiscan Biomedical Corporation Fluid analysis system
WO2011014673A1 (en) * 2009-07-31 2011-02-03 Cholestech Corporation Automated lateral flow immunoassay cassette with improved flow properties
US9125603B2 (en) 2009-08-11 2015-09-08 Abbott Diabetes Care Inc. Analyte sensor ports
EP2585165B1 (en) 2010-05-03 2017-06-21 Optiscan Biomedical Corporation Adjustable connector, improved fluid flow and reduced clotting risk
KR102021874B1 (en) 2011-04-06 2019-11-04 클라인 메디칼 리미티드 Spectroscopic analyser
WO2013006716A1 (en) 2011-07-06 2013-01-10 Optiscan Biomedical Corporation Sample cell for fluid analysis system
WO2013062554A1 (en) * 2011-10-27 2013-05-02 Hewlett-Packard Development Company, L.P. Apparatus for filtering species
JP5998471B2 (en) * 2011-12-20 2016-09-28 セイコーエプソン株式会社 adapter
US10640807B2 (en) 2011-12-29 2020-05-05 S.D. Sight Diagnostics Ltd Methods and systems for detecting a pathogen in a biological sample
US9289110B2 (en) * 2012-04-05 2016-03-22 Stryker Corporation Control for surgical fluid management pump system
KR20150021578A (en) 2012-06-19 2015-03-02 클라인 메디칼 리미티드 Spectroscopic analysis
WO2014188405A1 (en) 2013-05-23 2014-11-27 Parasight Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for preparing a monolayer of cells, particularly suitable for diagnosis
US20150133861A1 (en) 2013-11-11 2015-05-14 Kevin P. McLennan Thermal management system and method for medical devices
WO2015095239A1 (en) 2013-12-18 2015-06-25 Optiscan Biomedical Corporation Systems and methods for detecting leaks
GB2523989B (en) 2014-01-30 2020-07-29 Insulet Netherlands B V Therapeutic product delivery system and method of pairing
WO2016014987A2 (en) 2014-07-24 2016-01-28 Thomas Jefferson University Long-term implantable monitoring system & methods of use
EP3957232A1 (en) 2014-07-24 2022-02-23 University Health Network Collection and analysis of data for diagnostic purposes
US10143795B2 (en) 2014-08-18 2018-12-04 Icu Medical, Inc. Intravenous pole integrated power, control, and communication system and method for an infusion pump
US9949673B2 (en) * 2014-08-26 2018-04-24 MAXIM lNTEGRATED PRODUCTS, INC. System, method and apparatus with multiple reservoirs for in situ calibration of implantable sensors
US10482595B2 (en) 2014-08-27 2019-11-19 S.D. Sight Diagnostics Ltd. System and method for calculating focus variation for a digital microscope
EP3258991B1 (en) 2015-02-18 2020-10-21 Insulet Corporation Fluid delivery and infusion devices, and methods of use thereof
ES2809505T3 (en) 2015-05-26 2021-03-04 Icu Medical Inc Disposable infusion fluid delivery device for programmable delivery of high volume drugs
US9498300B1 (en) * 2015-07-30 2016-11-22 Novartis Ag Communication system for surgical devices
CN105079914A (en) * 2015-08-28 2015-11-25 苏州新区明基高分子医疗器械有限公司 Infusion support with function of automatic alarming
EP3859425B1 (en) 2015-09-17 2024-04-17 S.D. Sight Diagnostics Ltd. Methods and apparatus for detecting an entity in a bodily sample
WO2017123525A1 (en) 2016-01-13 2017-07-20 Bigfoot Biomedical, Inc. User interface for diabetes management system
AU2017207484B2 (en) 2016-01-14 2021-05-13 Bigfoot Biomedical, Inc. Adjusting insulin delivery rates
US11733150B2 (en) * 2016-03-30 2023-08-22 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
EP3455610B1 (en) 2016-05-11 2023-01-04 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
EP3455626A1 (en) 2016-05-11 2019-03-20 S.D. Sight Diagnostics Ltd. Performing optical measurements on a sample
US10765807B2 (en) 2016-09-23 2020-09-08 Insulet Corporation Fluid delivery device with sensor
US10413658B2 (en) 2017-03-31 2019-09-17 Capillary Biomedical, Inc. Helical insertion infusion device
JP6967387B2 (en) 2017-07-14 2021-11-17 株式会社堀場製作所 Gas analyzers, programs for gas analyzers, and gas analysis methods
US10466173B2 (en) * 2017-10-06 2019-11-05 Wyatt Technology Corporation Optical flow cell assembly incorporating a replaceable transparent flow cell
US11921272B2 (en) 2017-11-14 2024-03-05 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
US11360065B2 (en) * 2018-03-16 2022-06-14 Teledyne Flir Detection, Inc. Calibration systems and methods for analyte detectors
USD928199S1 (en) 2018-04-02 2021-08-17 Bigfoot Biomedical, Inc. Medication delivery device with icons
CN112236826A (en) 2018-05-04 2021-01-15 英赛罗公司 Safety constraints for drug delivery systems based on control algorithms
JP2022501139A (en) 2018-09-28 2022-01-06 インスレット コーポレイション Activity mode for artificial pancreas system
WO2020077223A1 (en) 2018-10-11 2020-04-16 Insulet Corporation Event detection for drug delivery system
USD920343S1 (en) 2019-01-09 2021-05-25 Bigfoot Biomedical, Inc. Display screen or portion thereof with graphical user interface associated with insulin delivery
USD939079S1 (en) 2019-08-22 2021-12-21 Icu Medical, Inc. Infusion pump
US11801344B2 (en) 2019-09-13 2023-10-31 Insulet Corporation Blood glucose rate of change modulation of meal and correction insulin bolus quantity
US11935637B2 (en) 2019-09-27 2024-03-19 Insulet Corporation Onboarding and total daily insulin adaptivity
WO2021113647A1 (en) 2019-12-06 2021-06-10 Insulet Corporation Techniques and devices providing adaptivity and personalization in diabetes treatment
CA3160695A1 (en) * 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Analyzing an analyte disposed within a medium
US11833329B2 (en) 2019-12-20 2023-12-05 Insulet Corporation Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
US11551802B2 (en) 2020-02-11 2023-01-10 Insulet Corporation Early meal detection and calorie intake detection
US11547800B2 (en) 2020-02-12 2023-01-10 Insulet Corporation User parameter dependent cost function for personalized reduction of hypoglycemia and/or hyperglycemia in a closed loop artificial pancreas system
US11324889B2 (en) 2020-02-14 2022-05-10 Insulet Corporation Compensation for missing readings from a glucose monitor in an automated insulin delivery system
US11607493B2 (en) 2020-04-06 2023-03-21 Insulet Corporation Initial total daily insulin setting for user onboarding
WO2021255726A1 (en) * 2020-06-16 2021-12-23 Ben Bashat Bergman Liron Whole blood sampling and monitoring device, method and software
US11684716B2 (en) 2020-07-31 2023-06-27 Insulet Corporation Techniques to reduce risk of occlusions in drug delivery systems
CN112147186B (en) * 2020-09-23 2023-07-18 深圳市科曼医疗设备有限公司 Specific protein analysis method and control device based on blood cell analyzer
US11904140B2 (en) 2021-03-10 2024-02-20 Insulet Corporation Adaptable asymmetric medicament cost component in a control system for medicament delivery
WO2023049900A1 (en) 2021-09-27 2023-03-30 Insulet Corporation Techniques enabling adaptation of parameters in aid systems by user input
US11439754B1 (en) 2021-12-01 2022-09-13 Insulet Corporation Optimizing embedded formulations for drug delivery

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017318A (en) * 1995-02-07 2000-01-25 Gensia Automedics, Inc. Feedback controlled drug delivery system
WO2000042907A1 (en) * 1999-01-22 2000-07-27 Instrumentation Metrics, Inc. System and method for noninvasive blood analyte measurements
US6157041A (en) * 1998-10-13 2000-12-05 Rio Grande Medical Technologies, Inc. Methods and apparatus for tailoring spectroscopic calibration models
US6470279B1 (en) * 1999-11-23 2002-10-22 James Samsoondar Method for calibrating spectrophotometric apparatus with synthetic fluids to measure plasma and serum analytes
US20030086073A1 (en) * 2001-11-08 2003-05-08 Braig James R. Reagent-less whole-blood glucose meter

Family Cites Families (263)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2797149A (en) * 1953-01-08 1957-06-25 Technicon International Ltd Methods of and apparatus for analyzing liquids containing crystalloid and non-crystalloid constituents
NL287532A (en) 1962-01-23
US3610226A (en) * 1968-02-27 1971-10-05 Anthony M Albisser A double lumen cannula for blood sampling
US3634039A (en) 1969-12-22 1972-01-11 Thomas L Brondy Blood testing machine
US3972614A (en) 1974-07-10 1976-08-03 Radiometer A/S Method and apparatus for measuring one or more constituents of a blood sample
US4119406A (en) * 1976-05-06 1978-10-10 Miles Laboratories, Inc. Calibration apparatus
US4151845A (en) 1977-11-25 1979-05-01 Miles Laboratories, Inc. Blood glucose control apparatus
US4447150A (en) 1981-02-27 1984-05-08 Bentley Laboratories Apparatus and method for measuring blood oxygen saturation
JPS5946854A (en) 1982-09-10 1984-03-16 Fuji Photo Film Co Ltd Multilayered analytical material
US4535786A (en) 1983-07-25 1985-08-20 Kater John A R Measurement of body fluid chemistry
US4573968A (en) * 1983-08-16 1986-03-04 Ivac Corporation Infusion and blood chemistry monitoring system
US4627014A (en) * 1984-04-09 1986-12-02 Eastman Kodak Company Method and apparatus for determination of an analyte and method of calibrating such apparatus
JPH0657250B2 (en) * 1984-06-29 1994-08-03 バクスター・インターナショナル・インコーポレーテッド Blood flow control device for blood extraction and reinfusion
JPS61203947A (en) * 1985-03-05 1986-09-09 工業技術院長 On-line monitoring apparatus for living body
US5164598A (en) 1985-08-05 1992-11-17 Biotrack Capillary flow device
US4756884A (en) 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US5059394A (en) * 1986-08-13 1991-10-22 Lifescan, Inc. Analytical device for the automated determination of analytes in fluids
US5049487A (en) * 1986-08-13 1991-09-17 Lifescan, Inc. Automated initiation of timing of reflectance readings
US4976720A (en) 1987-01-06 1990-12-11 Advanced Cardiovascular Systems, Inc. Vascular catheters
AT391998B (en) * 1987-02-02 1990-12-27 Falko Dr Skrabal Device for determining the concentration of at least one medicinal substance in living organisms
US4849340A (en) 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
GB8710610D0 (en) 1987-05-05 1987-06-10 British Res Agricult Eng Rotor assemblies
US4940527A (en) * 1987-06-01 1990-07-10 Abbott Laboratories Two-part test cartridge for centrifuge
US4781458A (en) 1987-11-30 1988-11-01 The United States Of America As Represented By The United States Department Of Energy Fiber optic apparatus for detecting molecular species by surface enhanced Raman spectroscopy
US4919596A (en) * 1987-12-04 1990-04-24 Pacesetter Infusion, Ltd. Fluid delivery control and monitoring apparatus for a medication infusion system
US5073500A (en) 1988-01-08 1991-12-17 Inax Corporation Method and apparatus for detecting urinary constituents
US5096669A (en) * 1988-09-15 1992-03-17 I-Stat Corporation Disposable sensing device for real time fluid analysis
US4974592A (en) 1988-11-14 1990-12-04 American Sensor Systems Corporation Continuous on-line blood monitoring system
US5204532A (en) * 1989-01-19 1993-04-20 Futrex, Inc. Method for providing general calibration for near infrared instruments for measurement of blood glucose
US6262798B1 (en) * 1992-09-29 2001-07-17 Board Of Regents, The University Of Texas System Method and apparatus for direct spectrophotometric measurements in unaltered whole blood
CA1328359C (en) 1989-03-27 1994-04-12 Michael D. Mintz Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling
US5134079A (en) 1989-03-27 1992-07-28 International Technidyne Corp. Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling
US4976270A (en) 1989-03-28 1990-12-11 Vanderbilt University Apparatus for continuously sampling plasma
JPH0312134A (en) * 1989-06-09 1991-01-21 Terumo Corp Method and instrument for measuring liquid of object or the like
US4975581A (en) * 1989-06-21 1990-12-04 University Of New Mexico Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids
CA2025330C (en) 1989-09-18 2002-01-22 David W. Osten Characterizing biological matter in a dynamic condition using near infrared spectroscopy
JPH0816649B2 (en) 1989-10-13 1996-02-21 富士写真フイルム株式会社 Liquid analysis calibration method
US5149501A (en) 1990-01-29 1992-09-22 Cirrus Diagnostics, Inc. Multichambered container and instrument for performing diagnostic tests
GB2243211A (en) * 1990-04-20 1991-10-23 Philips Electronic Associated Analytical instrument and method of calibrating an analytical instrument
US5066859A (en) 1990-05-18 1991-11-19 Karkar Maurice N Hematocrit and oxygen saturation blood analyzer
US5249584A (en) 1990-05-18 1993-10-05 Karkar Maurice N Syringe for hematocrit and oxygen saturation blood analyzer
US5178603A (en) * 1990-07-24 1993-01-12 Baxter International, Inc. Blood extraction and reinfusion flow control system and method
US5165406A (en) * 1990-09-13 1992-11-24 Via Medical Corporation Electrochemical sensor apparatus and method
US6266546B1 (en) 1990-10-06 2001-07-24 In-Line Diagnostics Corporation System for noninvasive hematocrit monitoring
US6681128B2 (en) * 1990-10-06 2004-01-20 Hema Metrics, Inc. System for noninvasive hematocrit monitoring
US5459677A (en) 1990-10-09 1995-10-17 Board Of Regents Of The University Of Washington Calibration transfer for analytical instruments
JPH04278450A (en) * 1991-03-04 1992-10-05 Adam Heller Biosensor and method for analyzing subject
US5371020A (en) 1991-09-19 1994-12-06 Radiometer A/S Method of photometric in vitro determination of the content of an analyte in a sample
EP0535700B1 (en) * 1991-10-04 1997-03-26 The Perkin-Elmer Corporation Method and apparatus for comparing spectra
EP0549341A1 (en) 1991-12-24 1993-06-30 W.R. Grace & Co.-Conn. Hollow fiber plasma sampler
US5452716A (en) * 1992-02-25 1995-09-26 Novo Nordisk A/S Method and device for in vivo measuring the concentration of a substance in the blood
US5331958A (en) 1992-03-31 1994-07-26 University Of Manitoba Spectrophotometric blood analysis
US5377674A (en) 1992-05-08 1995-01-03 Kuestner; J. Todd Method for non-invasive and in-vitro hemoglobin concentration measurement
US5357953A (en) 1992-05-21 1994-10-25 Puritan-Bennett Corporation Measurement device and method of calibration
US5355880A (en) 1992-07-06 1994-10-18 Sandia Corporation Reliable noninvasive measurement of blood gases
US6411832B1 (en) 1992-07-15 2002-06-25 Optix Lp Method of improving reproducibility of non-invasive measurements
US5434412A (en) 1992-07-15 1995-07-18 Myron J. Block Non-spectrophotometric measurement of analyte concentrations and optical properties of objects
US5330634A (en) * 1992-08-28 1994-07-19 Via Medical Corporation Calibration solutions useful for analyses of biological fluids and methods employing same
US5296706A (en) 1992-12-02 1994-03-22 Critikon, Inc. Shutterless mainstream discriminating anesthetic agent analyzer
US5398681A (en) * 1992-12-10 1995-03-21 Sunshine Medical Instruments, Inc. Pocket-type instrument for non-invasive measurement of blood glucose concentration
US5615672A (en) * 1993-01-28 1997-04-01 Optiscan, Inc. Self-emission noninvasive infrared spectrophotometer with body temperature compensation
US5515847A (en) 1993-01-28 1996-05-14 Optiscan, Inc. Self-emission noninvasive infrared spectrophotometer
US5313941A (en) 1993-01-28 1994-05-24 Braig James R Noninvasive pulsed infrared spectrophotometer
EP0631137B1 (en) * 1993-06-25 2002-03-20 Edward W. Stark Glucose related measurement method and apparatus
DK88893D0 (en) * 1993-07-30 1993-07-30 Radiometer As A METHOD AND APPARATUS FOR DETERMINING THE CONTENT OF A CONSTITUENT OF BLOOD OF AN INDIVIDUAL
US5435309A (en) 1993-08-10 1995-07-25 Thomas; Edward V. Systematic wavelength selection for improved multivariate spectral analysis
WO1995006431A2 (en) 1993-08-24 1995-03-09 Robinson Mark R A robust accurate non-invasive analyte monitor
US5553615A (en) 1994-01-31 1996-09-10 Minnesota Mining And Manufacturing Company Method and apparatus for noninvasive prediction of hematocrit
US5431174A (en) * 1994-04-04 1995-07-11 Via Medical Corporation Method of fluid delivery and collection
WO1995031928A1 (en) 1994-05-20 1995-11-30 Kuenst Hermann Transcutaneous, non-bloody determination of the concentration of substances in the blood
CA2156226C (en) * 1994-08-25 1999-02-23 Takayuki Taguchi Biological fluid analyzing device and method
US5697366A (en) * 1995-01-27 1997-12-16 Optical Sensors Incorporated In situ calibration system for sensors located in a physiologic line
US5697899A (en) 1995-02-07 1997-12-16 Gensia Feedback controlled drug delivery system
US5692503A (en) 1995-03-10 1997-12-02 Kuenstner; J. Todd Method for noninvasive (in-vivo) total hemoglobin, oxyhemogolobin, deoxyhemoglobin, carboxyhemoglobin and methemoglobin concentration determination
US5615673A (en) * 1995-03-27 1997-04-01 Massachusetts Institute Of Technology Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes
US5724268A (en) * 1995-06-29 1998-03-03 Chiron Diagnostics Corporation Apparatus and methods for the analytical determination of sample component concentrations that account for experimental error
US5657754A (en) 1995-07-10 1997-08-19 Rosencwaig; Allan Apparatus for non-invasive analyses of biological compounds
SG38866A1 (en) * 1995-07-31 1997-04-17 Instrumentation Metrics Inc Liquid correlation spectrometry
JPH09159606A (en) * 1995-07-31 1997-06-20 Instrumentation Metrics Inc Liquid-correlation spectrometry
US5606164A (en) * 1996-01-16 1997-02-25 Boehringer Mannheim Corporation Method and apparatus for biological fluid analyte concentration measurement using generalized distance outlier detection
US7016713B2 (en) 1995-08-09 2006-03-21 Inlight Solutions, Inc. Non-invasive determination of direction and rate of change of an analyte
US6240306B1 (en) * 1995-08-09 2001-05-29 Rio Grande Medical Technologies, Inc. Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration
US5636633A (en) * 1995-08-09 1997-06-10 Rio Grande Medical Technologies, Inc. Diffuse reflectance monitoring apparatus
US6152876A (en) * 1997-04-18 2000-11-28 Rio Grande Medical Technologies, Inc. Method for non-invasive blood analyte measurement with improved optical interface
WO1997019340A1 (en) * 1995-11-21 1997-05-29 Cme Telemetrix Inc. Apparatus and method for rapid spectrophotometric pre-test screen of specimen for a blood analyzer
US5747806A (en) * 1996-02-02 1998-05-05 Instrumentation Metrics, Inc Method and apparatus for multi-spectral analysis in noninvasive nir spectroscopy
US6040578A (en) * 1996-02-02 2000-03-21 Instrumentation Metrics, Inc. Method and apparatus for multi-spectral analysis of organic blood analytes in noninvasive infrared spectroscopy
JP3090692B2 (en) 1996-02-28 2000-09-25 株式会社分子バイオホトニクス研究所 Enzyme reaction measuring method and its measuring device
GB9611011D0 (en) * 1996-05-25 1996-07-31 Cme Telemetrix Inc Measurement of bile pigments in serum or plasma
SE9602298D0 (en) 1996-06-11 1996-06-11 Siemens Elema Ab Arrangement for analyzing body fluids
AT404513B (en) 1996-07-12 1998-12-28 Avl Verbrennungskraft Messtech METHOD AND MEASURING ARRANGEMENT FOR THE OPTICAL DETERMINATION OF TOTAL HEMOGLOBIN CONCENTRATION
US5758643A (en) * 1996-07-29 1998-06-02 Via Medical Corporation Method and apparatus for monitoring blood chemistry
US5871442A (en) 1996-09-10 1999-02-16 International Diagnostics Technologies, Inc. Photonic molecular probe
JP3121356B2 (en) * 1997-01-17 2000-12-25 ビア メディカル コーポレイション Calibration methods for sensors used in diagnostic tests
JP3394262B2 (en) 1997-02-06 2003-04-07 セラセンス、インク． Small volume in vitro analyte sensor
US5842979A (en) 1997-02-14 1998-12-01 Ohmeda Inc. Method and apparatus for improved photoplethysmographic monitoring of oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin and methemoglobin
JP2001513675A (en) 1997-02-27 2001-09-04 ミネソタ マイニング アンド マニュファクチャリング カンパニー Cassette for measuring blood parameters
EP0967954B1 (en) * 1997-03-03 2006-07-05 NIR Diagnostics Inc. APPARATUS FOR determining the concentration of INTERFERENTS IN PLASMA
US5900632A (en) 1997-03-12 1999-05-04 Optiscan Biomedical Corporation Subsurface thermal gradient spectrometry
US6161028A (en) * 1999-03-10 2000-12-12 Optiscan Biomedical Corporation Method for determining analyte concentration using periodic temperature modulation and phase detection
TW352335B (en) * 1997-03-25 1999-02-11 Matsushita Electric Works Ltd Method of determining a glucose concentration in a target by using near-infrared spectroscopy
US5891024A (en) * 1997-04-09 1999-04-06 Ohmeda Inc. Two stage calibration and analyte measurement scheme for spectrophotomeric analysis
US6285448B1 (en) 1997-05-05 2001-09-04 J. Todd Kuenstner Clinical analyte determination by infrared spectroscopy
US7267665B2 (en) * 1999-06-03 2007-09-11 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US5963335A (en) * 1997-06-25 1999-10-05 Waters Instruments, Inc. Means and method for measuring absorption of radiation-scattering samples
US5944660A (en) 1997-07-08 1999-08-31 Optical Sensors Incorporated Disposable cartridge assembly with optional integrated temperature control system, and systems containing same
US6066243A (en) 1997-07-22 2000-05-23 Diametrics Medical, Inc. Portable immediate response medical analyzer having multiple testing modules
US6115673A (en) * 1997-08-14 2000-09-05 Instrumentation Metrics, Inc. Method and apparatus for generating basis sets for use in spectroscopic analysis
US7010336B2 (en) * 1997-08-14 2006-03-07 Sensys Medical, Inc. Measurement site dependent data preprocessing method for robust calibration and prediction
US7039446B2 (en) * 2001-01-26 2006-05-02 Sensys Medical, Inc. Indirect measurement of tissue analytes through tissue properties
US6121050A (en) 1997-08-29 2000-09-19 Han; Chi-Neng Arthur Analyte detection systems
GB2329015B (en) * 1997-09-05 2002-02-13 Samsung Electronics Co Ltd Method and device for noninvasive measurement of concentrations of blood components
US6200287B1 (en) * 1997-09-05 2001-03-13 Gambro, Inc. Extracorporeal blood processing methods and apparatus
JP2001515782A (en) 1997-09-12 2001-09-25 ザ、ボード、オブ、トラスティーズ、オブ、ザ、リーランド、スタンフォード、ジュニア、ユニバーシティ Flow-through microcentrifuge
US6117290A (en) 1997-09-26 2000-09-12 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
US5941821A (en) 1997-11-25 1999-08-24 Trw Inc. Method and apparatus for noninvasive measurement of blood glucose by photoacoustics
US6579690B1 (en) * 1997-12-05 2003-06-17 Therasense, Inc. Blood analyte monitoring through subcutaneous measurement
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
US6049762A (en) * 1997-12-18 2000-04-11 Perkin Elmer Llc Standardizing a spectrometric instrument
US6055840A (en) 1998-01-21 2000-05-02 Industrial Scientific Corporation Method and apparatus for determining concentration of a gas
US6694157B1 (en) 1998-02-10 2004-02-17 Daedalus I , L.L.C. Method and apparatus for determination of pH pCO2, hemoglobin, and hemoglobin oxygen saturation
DE69935477D1 (en) 1998-02-10 2007-04-26 Daedalus I Llc DEVICE FOR DETERMINING pH, pCO2, HEMOGLOBIN AND HEMOGLOBINE OXYGEN SATURATION
JP2000116027A (en) * 1998-03-10 2000-04-21 Fiderikkusu:Kk Power supply device
US6122052A (en) * 1998-04-27 2000-09-19 Perkin Elmer Llc Computer operated spectrometric instrument and associated calculator
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6084661A (en) 1998-05-07 2000-07-04 Worcestor Polytechnic Institute Optical method and apparatus for measuring carbon monoxide in non-hemolyzed blood
US6662030B2 (en) * 1998-05-18 2003-12-09 Abbott Laboratories Non-invasive sensor having controllable temperature feature
US6226082B1 (en) * 1998-06-25 2001-05-01 Amira Medical Method and apparatus for the quantitative analysis of a liquid sample with surface enhanced spectroscopy
ES2275246T3 (en) 1998-07-03 2007-06-01 Precisense A/S OPTICAL SENSOR FOR THE MENTION OF ANALYTICS IN SITU.
US6183972B1 (en) 1998-07-27 2001-02-06 Bayer Corporation Method for the determination of analyte concentration in a lateral flow sandwich immunoassay exhibiting high-dose hook effect
US6304766B1 (en) 1998-08-26 2001-10-16 Sensors For Medicine And Science Optical-based sensing devices, especially for in-situ sensing in humans
ES2306525T3 (en) 1998-08-26 2008-11-01 Sensors For Medicine And Science, Inc. OPTICAL-BASED DETECTION DEVICES.
US6087182A (en) 1998-08-27 2000-07-11 Abbott Laboratories Reagentless analysis of biological samples
US6393310B1 (en) 1998-09-09 2002-05-21 J. Todd Kuenstner Methods and systems for clinical analyte determination by visible and infrared spectroscopy
US6064898A (en) 1998-09-21 2000-05-16 Essential Medical Devices Non-invasive blood component analyzer
WO2000018289A1 (en) * 1998-09-30 2000-04-06 Cygnus, Inc. Method and device for predicting physiological values
US6441388B1 (en) * 1998-10-13 2002-08-27 Rio Grande Medical Technologies, Inc. Methods and apparatus for spectroscopic calibration model transfer
US7098037B2 (en) * 1998-10-13 2006-08-29 Inlight Solutions, Inc. Accommodating subject and instrument variations in spectroscopic determinations
US6615061B1 (en) 1998-11-23 2003-09-02 Abbott Laboratories Optical sensor having a selectable sampling distance for determination of analytes
US6496260B1 (en) 1998-12-23 2002-12-17 Molecular Devices Corp. Vertical-beam photometer for determination of light absorption pathlength
US6280381B1 (en) 1999-07-22 2001-08-28 Instrumentation Metrics, Inc. Intelligent system for noninvasive blood analyte prediction
US6512937B2 (en) * 1999-07-22 2003-01-28 Sensys Medical, Inc. Multi-tier method of developing localized calibration models for non-invasive blood analyte prediction
US6697654B2 (en) * 1999-07-22 2004-02-24 Sensys Medical, Inc. Targeted interference subtraction applied to near-infrared measurement of analytes
US6675029B2 (en) 1999-07-22 2004-01-06 Sensys Medical, Inc. Apparatus and method for quantification of tissue hydration using diffuse reflectance spectroscopy
US6196046B1 (en) * 1999-08-25 2001-03-06 Optiscan Biomedical Corporation Devices and methods for calibration of a thermal gradient spectrometer
US6741875B1 (en) * 1999-08-31 2004-05-25 Cme Telemetrix Inc. Method for determination of analytes using near infrared, adjacent visible spectrum and an array of longer near infrared wavelengths
US6261065B1 (en) 1999-09-03 2001-07-17 Baxter International Inc. System and methods for control of pumps employing electrical field sensing
US6504614B1 (en) * 1999-10-08 2003-01-07 Rio Grande Medical Technologies, Inc. Interferometer spectrometer with reduced alignment sensitivity
US6411373B1 (en) 1999-10-08 2002-06-25 Instrumentation Metrics, Inc. Fiber optic illumination and detection patterns, shapes, and locations for use in spectroscopic analysis
US6611777B2 (en) * 1999-11-23 2003-08-26 James Samsoondar Method for calibrating spectrophotometric apparatus
EP1251772B1 (en) 1999-12-22 2012-11-14 Orsense Ltd. A method of optical measurements for determining various parameters of the patient's blood
AU2001238011A1 (en) 2000-01-31 2001-08-07 Board Of Regents, The University Of Texas System System for transferring fluid samples through a sensor array
US6649416B1 (en) 2000-02-18 2003-11-18 Trustees Of Tufts College Intelligent electro-optical sensor array and method for analyte detection
US6751490B2 (en) 2000-03-01 2004-06-15 The Board Of Regents Of The University Of Texas System Continuous optoacoustic monitoring of hemoglobin concentration and hematocrit
US6512577B1 (en) * 2000-03-13 2003-01-28 Richard M. Ozanich Apparatus and method for measuring and correlating characteristics of fruit with visible/near infra-red spectrum
JP3847053B2 (en) * 2000-03-15 2006-11-15 純 菊地 Blood analyzer
US6736783B2 (en) * 2000-04-12 2004-05-18 Merck & Co., Inc. Automated blood sampling apparatus
WO2001088510A2 (en) * 2000-05-18 2001-11-22 Argose, Inc. Pre-and post-processing of spectral data for calibration using multivariate analysis techniques
JP3407006B2 (en) * 2000-11-30 2003-05-19 生物系特定産業技術研究推進機構 Rapid determination of mammalian plasma components using visible and near-infrared spectral information
US6645142B2 (en) * 2000-12-01 2003-11-11 Optiscan Biomedical Corporation Glucose monitoring instrument having network connectivity
US6560471B1 (en) * 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US7244232B2 (en) 2001-03-07 2007-07-17 Biomed Solutions, Llc Process for identifying cancerous and/or metastatic cells of a living organism
US6574490B2 (en) * 2001-04-11 2003-06-03 Rio Grande Medical Technologies, Inc. System for non-invasive measurement of glucose in humans
US7202091B2 (en) * 2001-04-11 2007-04-10 Inlight Solutions, Inc. Optically similar reference samples
US7139598B2 (en) * 2002-04-04 2006-11-21 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using tissue fluorescence
US6862091B2 (en) * 2001-04-11 2005-03-01 Inlight Solutions, Inc. Illumination device and method for spectroscopic analysis
US6865408B1 (en) * 2001-04-11 2005-03-08 Inlight Solutions, Inc. System for non-invasive measurement of glucose in humans
US7756558B2 (en) 2004-05-24 2010-07-13 Trutouch Technologies, Inc. Apparatus and methods for mitigating the effects of foreign interferents on analyte measurements in spectroscopy
US6748250B1 (en) * 2001-04-27 2004-06-08 Medoptix, Inc. Method and system of monitoring a patient
US6890291B2 (en) 2001-06-25 2005-05-10 Mission Medical, Inc. Integrated automatic blood collection and processing unit
US6687620B1 (en) * 2001-08-01 2004-02-03 Sandia Corporation Augmented classical least squares multivariate spectral analysis
US6788965B2 (en) * 2001-08-03 2004-09-07 Sensys Medical, Inc. Intelligent system for detecting errors and determining failure modes in noninvasive measurement of blood and tissue analytes
US20040147034A1 (en) * 2001-08-14 2004-07-29 Gore Jay Prabhakar Method and apparatus for measuring a substance in a biological sample
CA2457753A1 (en) 2001-08-14 2003-02-27 Purdue Research Foundation Measuring a substance in a biological sample
US6678542B2 (en) * 2001-08-16 2004-01-13 Optiscan Biomedical Corp. Calibrator configured for use with noninvasive analyte-concentration monitor and employing traditional measurements
JP4512363B2 (en) 2001-08-22 2010-07-28 インストゥルメンテイション ラボラトリー カンパニー Method and apparatus for calibrating electrochemical sensors
AU2002332915A1 (en) * 2001-09-07 2003-03-24 Argose, Inc. Portable non-invasive glucose monitor
JP2003102710A (en) * 2001-09-30 2003-04-08 Hiroshi Otsuka Blood analysis method and device
FI20011918A0 (en) * 2001-10-01 2001-10-01 Mirhava Ltd Automatic vascular connection control device
US7061593B2 (en) 2001-11-08 2006-06-13 Optiscan Biomedical Corp. Device and method for in vitro determination of analyte concentrations within body fluids
US6989891B2 (en) * 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
US6958809B2 (en) 2001-11-08 2005-10-25 Optiscan Biomedical Corporation Reagent-less whole-blood glucose meter
US6731961B2 (en) * 2001-11-09 2004-05-04 Optiscan Biomedical Corp. Method for transforming phase spectra to absorption spectra
US7009180B2 (en) * 2001-12-14 2006-03-07 Optiscan Biomedical Corp. Pathlength-independent methods for optically determining material composition
US6862534B2 (en) * 2001-12-14 2005-03-01 Optiscan Biomedical Corporation Method of determining an analyte concentration in a sample from an absorption spectrum
DE10163775A1 (en) 2001-12-22 2003-07-03 Roche Diagnostics Gmbh Analysis system for determining an analyte concentration taking into account sample and analyte-independent changes in light intensity
US8858434B2 (en) 2004-07-13 2014-10-14 Dexcom, Inc. Transcutaneous analyte sensor
DE60337038D1 (en) 2002-03-22 2011-06-16 Animas Technologies Llc Performance improvement of an analyte monitoring device
US6684099B2 (en) * 2002-04-04 2004-01-27 Inlight Solutions, Inc. Apparatus and method for reducing spectral complexity in optical sampling
US7725144B2 (en) * 2002-04-04 2010-05-25 Veralight, Inc. Determination of disease state using raman spectroscopy of tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7569184B2 (en) 2002-04-23 2009-08-04 Home Access Health Corporation Quantitative analysis of a biological sample of unknown quantity
US7189314B1 (en) 2002-09-06 2007-03-13 Sensicore, Inc. Method and apparatus for quantitative analysis
US7243030B2 (en) 2002-10-25 2007-07-10 Liposcience, Inc. Methods, systems and computer programs for deconvolving the spectral contribution of chemical constituents with overlapping signals
US7338802B2 (en) * 2002-10-30 2008-03-04 Radiometer Medical Aps Method of performing calibration and quality control of a sensor and apparatus for performing the method
US7248912B2 (en) * 2002-10-31 2007-07-24 The Regents Of The University Of California Tissue implantable sensors for measurement of blood solutes
US6931328B2 (en) 2002-11-08 2005-08-16 Optiscan Biomedical Corp. Analyte detection system with software download capabilities
US6983177B2 (en) 2003-01-06 2006-01-03 Optiscan Biomedical Corporation Layered spectroscopic sample element with microporous membrane
US20040132167A1 (en) * 2003-01-06 2004-07-08 Peter Rule Cartridge lance
US20040132168A1 (en) 2003-01-06 2004-07-08 Peter Rule Sample element for reagentless whole blood glucose meter
US7326573B2 (en) 2003-01-10 2008-02-05 Beckman Coulter, Inc. Assay procedures and apparatus
EP1443780B1 (en) * 2003-01-30 2013-05-29 Accenture Global Services Limited Event data acquisition and transmission system
EP1447665B1 (en) 2003-02-11 2016-06-29 Bayer HealthCare LLC Method for reducing effect of hematocrit on measurement of an analyte in whole blood
EP1613208A1 (en) 2003-04-01 2006-01-11 Glucon Inc. Photoacoustic assay method and apparatus
US8718943B2 (en) 2003-04-01 2014-05-06 Abbott Diabetes Care Inc. Method and device for utilizing analyte levels to assist in the treatment of diabetes
US20040204868A1 (en) * 2003-04-09 2004-10-14 Maynard John D. Reduction of errors in non-invasive tissue sampling
CA2522484A1 (en) 2003-04-15 2004-10-28 Optiscan Biomedical Corporation Sample element with barrier material
EP1620715A1 (en) 2003-04-15 2006-02-01 Optiscan Biomedical Corporation Sample element for use in material analysis
EP1620004A2 (en) 2003-04-15 2006-02-01 Optiscan Biomedical Corporation Dual measurement analyte detection system
US7271912B2 (en) 2003-04-15 2007-09-18 Optiscan Biomedical Corporation Method of determining analyte concentration in a sample using infrared transmission data
AU2004230531A1 (en) 2003-04-15 2004-10-28 Optiscan Biomedical Corporation Sample element qualification
US20040241736A1 (en) 2003-05-21 2004-12-02 Hendee Shonn P. Analyte determinations
US7544503B2 (en) 2003-06-06 2009-06-09 Koninklijke Philips Electronics N.V. Apparatus for the pH determination of blood and method therefor
US7867369B2 (en) 2003-06-20 2011-01-11 Roche Diagnostics Operations, Inc. Biosensor with multiple electrical functionalities
US7424318B2 (en) 2003-12-05 2008-09-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7460898B2 (en) 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7366556B2 (en) 2003-12-05 2008-04-29 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7467003B2 (en) 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US6931327B2 (en) * 2003-08-01 2005-08-16 Dexcom, Inc. System and methods for processing analyte sensor data
KR20110041579A (en) 2003-08-15 2011-04-21 애니머스 테크놀로지스 엘엘씨 Microprocessors, devices, and methods for use in monitoring of physiological analytes
US20050073690A1 (en) * 2003-10-03 2005-04-07 Abbink Russell E. Optical spectroscopy incorporating a vertical cavity surface emitting laser (VCSEL)
EP1711790B1 (en) 2003-12-05 2010-09-08 DexCom, Inc. Calibration techniques for a continuous analyte sensor
EP1711791B1 (en) 2003-12-09 2014-10-15 DexCom, Inc. Signal processing for continuous analyte sensor
US7092832B2 (en) * 2003-12-11 2006-08-15 Inlight Solutions, Inc. Adaptive compensation for measurement distortions in spectroscopy
EP2659831B1 (en) 2003-12-18 2016-11-30 Metronom Health, Inc. Stabilized oxygen transport matrix
US8948836B2 (en) 2003-12-26 2015-02-03 Medtronic Minimed, Inc. Implantable apparatus for sensing multiple parameters
US20050187438A1 (en) 2004-02-24 2005-08-25 Skymoon Research & Development, Llc Anti-stokes raman in vivo probe of analyte concentrations through the human nail
US20050227370A1 (en) 2004-03-08 2005-10-13 Ramel Urs A Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays
CA2460898A1 (en) 2004-03-09 2005-09-09 James Samsoondar Apparatus and method for combining in vivo and in vitro testing
US7066777B2 (en) * 2004-03-12 2006-06-27 Maselter John F Marine inboard/outboard system
US20060009727A1 (en) * 2004-04-08 2006-01-12 Chf Solutions Inc. Method and apparatus for an extracorporeal control of blood glucose
WO2005110601A1 (en) 2004-05-07 2005-11-24 Optiscan Biomedical Corporation Sample element with separator
US7277210B2 (en) 2005-07-21 2007-10-02 C8 Medisensors Inc. Measuring spectral lines from an analyte using multiplexed holograms and polarization manipulation
US7608042B2 (en) 2004-09-29 2009-10-27 Intellidx, Inc. Blood monitoring system
US20060229531A1 (en) 2005-02-01 2006-10-12 Daniel Goldberger Blood monitoring system
AU2005299929A1 (en) * 2004-10-21 2006-05-04 Optiscan Biomedical Corporation Method and apparatus for determining an analyte concentration in a sample having interferents
GB0426822D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
US20060142720A1 (en) * 2004-12-23 2006-06-29 Zander Teresa M Package and dispensing system for personal care articles
US20060167350A1 (en) * 2005-01-27 2006-07-27 Monfre Stephen L Multi-tier method of developing localized calibration models for non-invasive blood analyte prediction
US20070083160A1 (en) 2005-10-06 2007-04-12 Hall W D System and method for assessing measurements made by a body fluid analyzing device
US7785258B2 (en) 2005-10-06 2010-08-31 Optiscan Biomedical Corporation System and method for determining a treatment dose for a patient
US7364562B2 (en) 2005-10-06 2008-04-29 Optiscan Biomedical Corp. Anti-clotting apparatus and methods for fluid handling system
US20060189926A1 (en) 2005-02-14 2006-08-24 Hall W D Apparatus and methods for analyzing body fluid samples
US20070081626A1 (en) 2005-02-14 2007-04-12 Peter Rule Method and apparatus for enhancing accuracy of an analyte detection system
US20060189925A1 (en) 2005-02-14 2006-08-24 Gable Jennifer H Methods and apparatus for extracting and analyzing a component of a bodily fluid
US20070103678A1 (en) 2005-02-14 2007-05-10 Sterling Bernhard B Analyte detection system with interferent identification and correction
US7616303B2 (en) 2005-04-25 2009-11-10 University Of Massachusetts Systems and methods for correcting optical reflectance measurements
US9103793B2 (en) 2005-07-22 2015-08-11 Massachusetts Institute Of Technology Intrinsic Raman spectroscopy
MX2008004520A (en) 2005-10-06 2008-09-04 Optiscan Biomedical Corp Fluid handling cassette system for body fluid analyzer.
CA2630094A1 (en) 2005-11-15 2007-05-24 Luminous Medical, Inc. Blood analyte determinations
EP1963832A2 (en) 2005-12-16 2008-09-03 Bayer Healthcare, LLC Dual transdermal analyte sensor assembly and methods of using the same
US20070179436A1 (en) 2005-12-21 2007-08-02 Braig James R Analyte detection system with periodic sample draw and laboratory-grade analyzer
WO2007100677A2 (en) 2006-02-22 2007-09-07 Vivum Nexus Llc Method and device for analyte measurement
WO2007120746A2 (en) 2006-04-11 2007-10-25 Optiscan Biomedical Corporation Anti-clotting apparatus and methods for fluid handling system
US20070258083A1 (en) 2006-04-11 2007-11-08 Optiscan Biomedical Corporation Noise reduction for analyte detection systems
US20070235346A1 (en) 2006-04-11 2007-10-11 Popovich Natasha D System and methods for providing corrected analyte concentration measurements
US20070278384A1 (en) 2006-06-01 2007-12-06 Optiscan Biomedical Corporation Method and apparatus for driving a radiation source
US7699973B2 (en) 2006-06-30 2010-04-20 Abbott Diabetes Care Inc. Rapid analyte measurement assay
CA2661904A1 (en) 2006-08-08 2008-02-21 Shaklee Corporation Systems and methods for measuring and improving blood chemistry
US7751863B2 (en) 2007-02-06 2010-07-06 Glumetrics, Inc. Optical determination of ph and glucose

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017318A (en) * 1995-02-07 2000-01-25 Gensia Automedics, Inc. Feedback controlled drug delivery system
US6157041A (en) * 1998-10-13 2000-12-05 Rio Grande Medical Technologies, Inc. Methods and apparatus for tailoring spectroscopic calibration models
WO2000042907A1 (en) * 1999-01-22 2000-07-27 Instrumentation Metrics, Inc. System and method for noninvasive blood analyte measurements
US6470279B1 (en) * 1999-11-23 2002-10-22 James Samsoondar Method for calibrating spectrophotometric apparatus with synthetic fluids to measure plasma and serum analytes
US20030086073A1 (en) * 2001-11-08 2003-05-08 Braig James R. Reagent-less whole-blood glucose meter

Also Published As

Publication number Publication date
US20070103678A1 (en) 2007-05-10
CA2951271C (en) 2019-05-21
EP2177895A2 (en) 2010-04-21
EP2302357A1 (en) 2011-03-30
US20060189858A1 (en) 2006-08-24
AU2006214523A1 (en) 2006-08-24
CA2597618C (en) 2017-01-10
US8140140B2 (en) 2012-03-20
DE602006019947D1 (en) 2011-03-17
JP2008530562A (en) 2008-08-07
US20060200070A1 (en) 2006-09-07
US20060200071A1 (en) 2006-09-07
EP1853165A2 (en) 2007-11-14
AU2006214523A2 (en) 2006-08-24
US20100234703A1 (en) 2010-09-16
ATE497361T1 (en) 2011-02-15
CA2951271A1 (en) 2006-08-24
CA2597618A1 (en) 2006-08-24
US7722537B2 (en) 2010-05-25
WO2006088792A3 (en) 2007-03-01
EP1853165B1 (en) 2011-02-02
WO2006088792A2 (en) 2006-08-24
AU2006214523B2 (en) 2011-11-17

Similar Documents

Publication Publication Date Title
EP2177895A3 (en) Method and apparatus for detection of multiple analytes
EP1738689A3 (en) System and method for non-invasive glucose monitoring
ATE332667T1 (en) METHOD AND DEVICE FOR COLLECTING PHYSIOLOGICAL SAMPLES
ATE490729T1 (en) DEVICE FOR MEASURING AN ANALYTE IN A BODY FLUID
WO2006091426A3 (en) Methods and apparatus for extracting and analyzing a bodily fluid
EP1598011A3 (en) Physiological sample collection devices and methods of using the same
EP1266625A3 (en) Percutaneous biological fluid sampling and analyte measurement device
DE60238914D1 (en) INTEGRATED BLOOD SAMPLE ANALYSIS SYSTEM WITH MULTI-USE SAMPLING MODULE
EP3432002A8 (en) Blood coagulation analyzer, blood coagulation analysis method, and computer program
EP2145684A3 (en) Microfluidic device, sample analyzing method using the same, and dilution ration measuring method
WO2005054811A3 (en) Method and apparatus for ultrasonic determination of hematocrit and hemoglobin concentrations
EP1069427A3 (en) Initiation of an analytical measurement procedure for blood
PL355356A1 (en) Method of taking a physiological sample as well as skin puncturing element, test strip and apparatus for determining concentration of analyte in a physiological sample
EP2278330A3 (en) Method and apparatus for rapid electrochemical analysis
WO2008040990A3 (en) Methods for determining an analyte concentration using signal processing algorithms
WO2011008581A3 (en) Devices, methods, and kits for determining analyte concentrations
TW200745543A (en) System and methods for providing corrected analyte concentration measurements
EP1775587A3 (en) A system and method of processing a current sample for calculating a glucose concentration
EP1164530A3 (en) System, method and biosensor apparatus for data communications with a personal data assistant
EP1312919A3 (en) Sample volume metering apparatus
EP2202511A3 (en) Quantitative analyzing method and quantitative analyzer using sensor
EP2494921A3 (en) Processing analyte sensor data
EP1975625A3 (en) Sample analyzer, sample analyzing method, and computer program product
WO2008022047A3 (en) Method of analyzing the composition of bodily fluids
EP1445329A3 (en) Method and test strip for determining glucose in blood

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AC Divisional application: reference to earlier application

Ref document number: 1853165

Country of ref document: EP

Kind code of ref document: P

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

RIN1 Information on inventor provided before grant (corrected)

Inventor name: GABLE, JENNIFER, H.

Inventor name: HALL, W., DALE

Inventor name: WITTE, KENNETH, G.

Inventor name: RULE, PETER

Inventor name: CALLICOAT, DAVID, N.

Inventor name: BRAIG, JAMES, R.

Inventor name: BERNHARD, B.

Inventor name: ZHENG, PENG

Inventor name: WECHSLER, MARK

Inventor name: KING, RICHARD, A.

Inventor name: KEENAN, RICHARD

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: OPTISCAN BIOMEDICAL CORPORATION

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

17P Request for examination filed

Effective date: 20101224

17Q First examination report despatched

Effective date: 20110119

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20110802