US 1438057 A
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Description (OCR text may contain errors)
P. Sv. P'ITTENGER.
APPLlcATloN FILED Dsc. 2, 1920.
1,438,057., Patent@ 1560.519221 l Patente-d Dec. 5, 1922. l
luNrifsn -srATiEs 'PAUL STEWART PITT-ENGER, 'OF PHILADELPHIA, BENNSYLVANIA, ASSIGNOR TO H., K.
MULFO'BD COMPANY, on rHrLAnnnrHIn, PENNSYLVANIA, n conreaAfrroN or PENNSYLVANIA. 7
Application led December 2, 1(9270. Serial No. 427,733.
To all wkom'it mayconcera:
Be it known thatI, UL VS'. PITTENGER, a citizen of the United States, residing in Philadelphia, Pennsylvania, have invented lVIedic'i'nal47 Packages, of'. which the following isa specification. I l
` In making tests vto ascertain the susceptibility of a patient to the proteins known` to cause various painful .lor distressing symptoms such'as those of. hay fever, rose cold, or the like, it is customary to note the skin reactions occurring when a small quantity of each of several proteins is applied to the previously scarified skin surface there being a peculiar and characteristic inflammation which occurs if the patient is susceptible to its action, within a definite. time after the protein has been administered.
One object of the present invention therefore, is to provide a convenient package for holding a small amount of a protein, together. with la scarifying needle for use in conveniently and' quickly carrying out the above tests ;-it being particularly desired that said package shall be of such a nature as will contain a relatively minute quantity of the protein, such as will be sufficient for a single test, and which by virtue of its inexpensive nature may be discarded afteruse.
These objects and other advantageous ends I attain as hereinafter set forth, reference being had to the accompanying drawin s, in which,
41g. l is a longitudinal vertical section on an enlarged scale, illustrating a medicinal package constructed in accordance with my invention;
Figs. 2 and 3 are longitudinal sections similar to Fig. l, illustrating modified forms of the invention; and
Fig. 4 is a longitudinal section of a glass tube from which one form of my package ma be conveniently made.
n Fig. 4 of the above drawings, l represents a suitable length of glass tubing, which in a typical case, is about two inches long and has through it a passage in the neighborhood of one thirty-second to one-sixteenth of an inch in diameter.
To prepare this tube for use l heat it in a suitable llame at a point near one end until it has so-,far softened that its walls come together fora short length and close off the passage 2 by a solid barrier 3, thereby ydividing said passage into two chambers 4' and 5I of which `the first is relatively short and' of small capacity and the second. is com- Y paratively long.
ordinary pointed sewing needle 6 having adjacent itsfblunt end Va flattened* portion such asis formedin connection with the customary thread eye 7. The `open end of the large chamber 5 is now heated in a suitable gas flame so that it is sealed as indicated at of the length of the chamber 5.
The tube with its contained needle 1s then.
"Ithen insert in the latter or longer cham-` ber v5 a scariier preferably in the form of an The package is now ready for '8 and at any suitable stage in the operation,- the tube is nicked at 9 by means of a file, preferably at a point about the middle use, and it may be storedor safely trans ported Without deterioration.
lWhen desired for use, the tube is broken by be-ing bent adjacent its middle and the break naturally occurs at the nicked point 9. The sterile needle 6 is then `used for scarifying a previously sterilized skin area to which the test is to be applied and thereafter is employed asa spoon or spatulafor transferring a minute quantity of the protein from the chamber 4 to the scariiied area. For this purpose the cap lOis removed and the blunt end of the needle isinserted in said protein which is usually in the form *y of a powder, whereupon a Small quantity of the latter enters and is retained bythe eye v or flattened portion of the needle lfrom whiohit may be delivered as desired to the and form in onerend thereof a small cavity l for holding` the desired small amount of protein. As before, this tubular chamber or recess may be made in any suitable manner and When filled with the protein is closed by a rubber or other suitable Cap or closure 10. The opposite end of the rod 11 in this form or my invention has fixed in it a steel seari- Atying` needle or point 129 although if desired it may be drawn out into a sharp soarifying point 18 as shown in Fig. 3.
ln any Case however, the package itself carries a scarifying point and is also provided with a chamber of relatively minute Capacity for containing `the small amount of protein required tor single test. Obviously other materials besides proteins may be placed in the Chamber 4 and While for the purpose oit making the tests above noted, said chamber is of relatively small capacity, it may be made larger and employed to con- 2L The combination oi a tubular body of f glass having its Walls fused together immediately adjacent one end to provide two elianibersoi1 which one is of relatively small capacity; cap removably closing said latter chamber; a subst-ance to be administered Within the-smaller chamber; and a sterile needle hermetieally sealed Within the larger Chamber.
. Peur erm/vani rrrrnNeEn.