|Publication number||US1547562 A|
|Publication date||Jul 28, 1925|
|Filing date||Jul 21, 1924|
|Priority date||Jul 21, 1924|
|Publication number||US 1547562 A, US 1547562A, US-A-1547562, US1547562 A, US1547562A|
|Inventors||Byrd Thomas Luther|
|Original Assignee||Byrd Thomas Luther|
|Export Citation||BiBTeX, EndNote, RefMan|
|Referenced by (18), Classifications (11)|
|External Links: USPTO, USPTO Assignment, Espacenet|
T. L. BYRD PIPETTE July 28, 1925.
Filed July 21, 1924 Quoru Patented July 28, 1925.
- UNITED STATES,
, PATENT OFFIQE.
momsrmrnnn BYBD, or MILWAUKEE, wrsoolvsnv.
Application filed July 21, 1824. Serial No. 727,248.
, kee and State of Wisconsin, have, invented certain new and useful Improvements in Pipettes, of which the following is a specification, reference beiiigvhad therein to the accompanying drawing.
- This invention relates to pipettes and the principal object of the invention is to provide a device of this character, which may be conveniently used for obtaining and diluting small quantities of blood to be subsequently patients. r
It has been found in actual. practice that the ordinary ipette, commonly used for obtaining blood fof' counting tests of the red and white corpuscles, is entirely unsuited to the .work of 0 taining blood for-su ar tests. In a pipette constructed for oitaining blood for counting the white cells, its usual used for sugar testsof diabetic capacity is about-.250 (30., whereas the red.
blood cell counting pipettes total capacity is approximately .425 cc. or a fraction over 1; cc. The adherence of blood to a capillary tube, which would'hold sufiicient for the process for which the resent device has beenconceived, would ma e a tube so long as to be totally impracticable, also the cleaning of a tube of this clfaracter, after each use, would be extremely tedious and costly.
It is, therefore, one of the objects of this invention to provide adevice which overcomes the difiiculties heretofore encountered and in which the blood can be conveniently retained and accurately diluted in an instrument whichmay be held at its ends between the thumb and forefinger.
In'the process of obtaining blood from a patient, the operator very often has to pause in the process toexpress more blood from the bleeding point, when only a small part of the required amount of blood necessary has been originally obtained and it is, therefore, another object of this invention to rovide a pipette having a substantially siform blood containing chamber, which will contain the required amount of blood and yet prevent the same from running out of the pipette and thus being lost.
Still another object of the invention is the provision of a pipette of relatively small dimensions longitudinally so that an elastic band may be stretched over the pi ette lengthwise and close both ends thereo effectively, thus permitting proper agitation of the diluted fluid without the possibility of losing an Further objectsof the invention will ap pear as the following specific description is read in connection with the accompanying drawing, which forms part of this application and in which:
Figure 1 is an elevation, showing the com plete pipette with the suction tube attached thereto; Fig. 2 is an enlarged longitudinal sectional view-with the suction tube removed;
' Fig. 3 is an elevation of the pipette with the suction tube removed and the end-closin band sprung. thereover;
igs. 4, 5, 6 and 7 are sections taken at various points throughout the length of the pipette, their position being indicated by the dotted lines in Fi 2.
' The pipette, as sIiown'in Fig. 1, comprises an-elongated tube of glass,fused quartz, or
similar transparent material, generally indicated at 1. The upper end of the pipette is provided with a flange 2, over which one end of a flexible and resilient tube 3 is adapted to be removably secured.
The opposite end of the tube 3 is similarly secured over a mouthpiece 4, which is utilized by the operator to produce a suction in the tube and ipette, so as to draw the blood from the b eeding point into the pipette in a well-known manner.
As shown in Fig.2, the bore 5 of the pipette is variously diametered. The lower portion or inlet end of the pipette is provided with a filiform passage 6 leading mto a substantially fusiform chamber 7 of somewhat larger diameter than the bore 6. The upper end of this chamber merges gradually into a second filiform passage 8, which in turn merges into a diluting chamber 9 of relatively large capacity compared with the chamber 7 and also fusiform in shape. This upper chamber also merges at its upper end into an attenuated passage 10 and, as
shown, contains a glass 'or fused quartz cube 11, which is utilized to facilitate the agitation and proper cominingling of the blood with the diluting fluid. Intermediate the chambers 7 and 9, the outer surface of the pipette is provided --'with a graduation mark 12, and. above the chamber 9 there is provided a second graduation'13. The lower graduation indicates that the bore up to this point contains cc. of blood, wl'iile the up per graduation indicates that t obtained to fill the bore of the pipette to the graduation 12. After this is done, end 6 is inserted in a suitable diluted fluid, such as distilled water or the like, and a sufiiclent quantity drawn into the tube to fill the bore up to the graduation 13. The tube 3 is then removed and a band, similar to that indicated at 14, is placed over the ends of the tube and the same grasped between the middle finger and thumb and shaken thoroughly 4 so that the cube 11 will effectively agitate and cause a thorou h intermingling of the two fluids. This uid may then. be expelled from the pipette and placed in a test tube. for making the usual tests for diabetes. What I claim is: 1. A ipettehavin spaced chambers, one of whic 1s substantia y fusiform.
2. A ipette having spaced chambers, one
' of whic 1s fusiform and a filiform passage connecting said chambers.
3. A pipette having a variousl diametered bore, including spaced 'cham rs.
4; A pipette having a variously diametered bore, including spaced connected chambers, one of which is substantially fusiform.
5. A pipette having a variously diametered bore, including spaced connected chambers, one of which is substantially fusiform and an agitating element in the other of said chambers.
6. A pipette constructed of transparent material and having a variously diametered bore intersected by spaced chambers, one of which is fusiform and a filiform entrance passage into said chamber.
7. pipette, constructed of transparent material and having a variously diametered bore intersected by spaced chambers, one of which is fusiform and a filiform passage 8. A pipette comprising a transparent body having a .variously diametered bore intersected by enlarged spaced chambers, a filiform inlet into said bore and a filiform outlet from one of said chambers.
9. A pipette comprising a transparent body having a variously diametered bore intersected by enlarged spaced chambers, a
filiform inlet into said bore and a filiform outlet from both of said chambers.
e bore to nuance i 10. A pipette comprising atrans arent body having a variously diametere bore including spaced chambers and graduations on opposite sides of one of said chambers. Y
11. A. pipette comprising a transparent body having a various diametered bore including spaced chambers and filiform asssages on opposite sides of said cha n, rs and graduatlons on said tube arranged -ad= jacent said filiform passages.
12. A pipette oomprislng a transparent body having a longltudinal bore and relmovable means for. closing the ends of said ore.
13. A pipette comprising a transparent body having a longitudinal bore and a flexible band for closing the ends of said bore.
14.. A ipette comprising a transparent body havmg a central bore including spaced chambers, one of which is fusiform and a loosely mounted a itating element in the other of said cham ers.
15. A pipette comprising a transparent body having acentral bore including spaced chambers, one of which is fusiform and a loosely mounted cubical agitating element in the other of said chambers.
- 16. A pipette com rising a transparent body have a central ore including spaced fusiform chambers, and a loosely mounted agitating element in one of said chambers. 17. A pipette of transparent material, havingtwo spaced fusiform chambers connected by a scaled neck with filiform bore, the opposite ends of 'said chambers terminating in tubular extensions of filiform bore, the upper of which is scaled and expands into a tube of indefinite contents constructed to receive a rubber tube, the lower having a capillary tube and tapering to a dull point. V
18. A pipette of transparent material, having a variously diametered bore including two fusiform chambers connected by a scaled tubular neck of minute bore, one of which chambers is one-tenth cc. capacity and terminates'in a tapering tube of minute bore, and'the other chamber being seven-tenths cc. capacity, tapering into a scaled tube of minute bore which expands into a tube ofindefinite capacity.
19. A- pipette consisting material and having a variously diametered bore that expands into fusif orm chambers of specific capacity, the inlet to one of said chambers being of capillary bore, the connecting neck'of said chambers also being of minute bore and scaled, and the outlet of the other chamber being contracted into a taperof transparent I form distention of one-tenth cc. cato receive and retain a rubber tube which pacity, converging into a scaled neck of terminates with a mouth iece. tubular form' with minute bore, which con- In testimony whereof affix my signature nects with and expands into another fusiin the presence of two witnesses.
5 form chamber of seven-tenths cc. ca- THOMAS LUTHER BYRD.
pacity, terminating in a scaled tube of mi- Witnesses: nute bore which expands into a tube of in-- CHARLES M. SCANLAN,
definite capacity whose end is constructed CARL KEMPF.
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US2893710 *||Nov 6, 1957||Jul 7, 1959||Henry Goodman||Tube container for paint|
|US3215500 *||Jun 12, 1961||Nov 2, 1965||Donald L Bittner||Laboratory mixer-separator|
|US3580686 *||Mar 17, 1969||May 25, 1971||Coulter Electronics||Vessel having intersample anticontamination construction|
|US3794035 *||Mar 7, 1972||Feb 26, 1974||Brenner N||Suction system for skin treatment|
|US4877585 *||Dec 9, 1987||Oct 31, 1989||Brandeis University||Dilution pipette device|
|US5174162 *||Jul 10, 1990||Dec 29, 1992||Hitachi, Ltd.||Pipetter, pipette tube, sample analyzing apparatus including them and method of mixing and pipetting liquids|
|US5544960 *||Aug 11, 1995||Aug 13, 1996||Sommovigo; Christopher V.||Faceted stirring object for solid and liquid food substances|
|US5773305 *||May 2, 1996||Jun 30, 1998||Bayer Corp.||Sample dilution module|
|US5823046 *||Jul 18, 1997||Oct 20, 1998||Schagerstroem; Tonie||Measuring vessel|
|US6261847||Jul 10, 1998||Jul 17, 2001||Bayer Corporation||Sample dilution module with offset mixing chamber|
|US6296452||Apr 28, 2000||Oct 2, 2001||Agilent Technologies, Inc.||Microfluidic pumping|
|US6533553||Oct 1, 2001||Mar 18, 2003||Agilent Technologies, Inc.||Microfluidic pumping|
|US7182915 *||Nov 27, 2002||Feb 27, 2007||Bristol-Myers Squibb Company||Pipette configurations and arrays thereof for measuring cellular electrical properties|
|US7452508 *||Nov 6, 2001||Nov 18, 2008||Jacobs Merrit N||Aspirating and mixing of liquids within a probe tip|
|US20020076826 *||Nov 6, 2001||Jun 20, 2002||Jacobs Merrit N.||Aspirating and mixing of liquids within a probe tip|
|US20030132109 *||Nov 27, 2002||Jul 17, 2003||Andrew Bullen||Pipette configurations and arrays thereof for measuring cellular electrical properties|
|US20080080302 *||Sep 29, 2007||Apr 3, 2008||Fujifilm Corporation||Droplet mixing method and apparatus|
|US20110189059 *||May 14, 2009||Aug 4, 2011||Andreas Johannes Boehm||Mixer for mixing a dental composition|
|U.S. Classification||422/514, 366/143, 366/241, 422/922, 366/130, 73/426, 366/342, 73/864.1|