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Publication numberUS1718595 A
Publication typeGrant
Publication dateJun 25, 1929
Filing dateMar 25, 1927
Priority dateMar 25, 1927
Publication numberUS 1718595 A, US 1718595A, US-A-1718595, US1718595 A, US1718595A
InventorsSmith Arthur E
Original AssigneeSmith Arthur E
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Ampul
US 1718595 A
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Description  (OCR text may contain errors)

June 25, 1929.

A. E. SMITH AMPUL Original Filed March 25, 1927 000,JJIIIIIII'IIII'IJIIIIJIM INVENTOR. ARTHUR E. SMITH A TTORNEY.

atented June 25, 1929.

ARTHUR E. SMITH, or LOS ANGELES, CALIFORNIA. AMPUL.

.Applicati on filed March This invention relates to a medicinal container or ainpul.

The main object of this invention is to provide an improved drug containing ampul wherein the drug in the ampul is hermetically sealed therein.

Another object of the invention'is to provide a drug containing ampul having an improved form of stopper therein for ejecting the contents of the ampul.

Another object of the invention is to provide an ampul having novel means thereon for coacting with a syringe to form a fluid tight seal between the syringe and the ampul.

A further object of the invention is'to provide a novel method of placing a fluid in an ampul.

Other objects of the invention will be apparent from the following description taken in connection with the accompanying drawing wherein Fig. 1 is a central longitudinal section through my improved medicinal container or ampul.

Fig. 2 is a side elevation on a reduced scale of the tube from which a single ampul is made.

Fig. 8 illustrates the first step in the forming of an ampul.

Fig. 4 illustrates the second step.

Fig. 5 illustrates the third step.

Fig. 6 is a fragmentary section showing the fourth step or the manner in which the fluid is placed in the ampul.

Fig. 7 is a side elevation of a completed ampul, and r Fig. 8 is a side elevation of an ampul showing it prepared for use in a syringe.

eferring to the drawings by reference characters I have indicated my improved ampul generally at 10. This ampul is adapted for use in a hypodermic syringe. The ampul may be of any desired size and is preferably of a size to hold the amount of drug necessary for one injection. d

The ampul 10 comprises an elongated body portion 11 terminating at one end in a reduced in a breakable tip 13. The other endof the body portion 11 merges into a constricted throat .14 which terminates in a breakable tip 15. The

tips 13 and 15 may be rendered readily separa- V ble from the ampul by scoring, notching, etching, or otherwise weakening them as indicated at 16 and 17 Y 25, 1927, Serial No. 178,388. Renewed May 10, 1929.

Within the ampul body 11 and adjacent the throat 14 I provide "astoppcr 18 which is preferably made of a good grade of rubber and fits the inner side walls of the ampul bod v rather tightly, enabling to expel the contents of the ampul through the tapered end 12 after the tip 13 has been broken therefrom. The stopper 18 is preferably provided on 1ts face ad acent the throat 14, as shown in the drawing, with a washer 19 having a tapered hub-20 thereon which is adapted to lit in a recess 21 of the stopper. The recess 21 has undercut ends 21. The hub 20 is provided with a. tapered aperture 22 extending therethrough. The hub 20 has a rolled terminal edge 20 which fits in the undercut portion 21 to unite the parts.

The tapered aperture ceive the tapered end of a plunger rod of of the stopper 18 may be concave as" at 23 so h t at when the Stopper 1S acting as a Piston to eject the contents of the ampul the peripheral edges of the concavity will be forced into tight engagement with the inner walls of the body port1on, thus preventing any of the fluid from leaking past the stopper as it is moved.

or forming a fluid tight seal between the ampul 10 and a syringe with which the ampul is used I provide on the tapered neck 12 j ust above the fracture 16, a resilient collar 24 which is preferably made of rubber.

.he foregoing ainpul is preferably made of a good grade of glass and is preferably formed from a length of glass tubing 25 as shown in Fig. 1. This tubing is first heated an has been formed and closed by the tip 13 the ampul is ready to be filled other fluid. To fill theampul 10 I insert through the with a drug or stopper 18 and into the interior of the ampul employed and I weakened at 16 and 17.

syringe the tip body 11 a pair of hollow needles 28 and 29 as shown in Fig. 6. The needle 28 is shown as having attached thereto a flexible hose 30 which is adapted to communicate with a source of drug supply (not shown).. As the drugenters the ampul body 11 through the needle 28 the air it displaces will pass out through the other hollow needle 29.

I have-described one manner in which the drug may be placed in the ampul body 11 and the air is removed therefrom by the needles 28 and 29 but various other methods may be do not wish to be held to any single method of accomplishing this. Upon the withdrawal of the needles 28 and 29 the elasticity of the stopper 18 will close the minute apertures madeby the needles and thus the fluid will not leak out through the needle punctures.

After the ampul has been filled with the desired drug the open end 26 is heated and drawn down to form the closed tip 15 and then it may be etched, scored, notched, or otherwise The collar 2& is then placed on the tapered neck 12 and the ampul is complete and ready for use (see Fig. 7)

To prepare the ampul 10 for use in a 13 is broken off at 16 and the tip 15 is broken off at 17 as clearly shown in Fig. 8. The ampul is .then placed in the syringe, the plunger of the syringe engages the stopper 18 and as the syringe plunger is moved towards the tapered end 12 the stopper 18 is caused to act as a piston to expel the contents of the ampul out through the tapered neck 12.

From the foregoing description it will be apparent that I have provided an improved form of container or ampul having therem a movable fluid restricting stopper, and wherein means is provided for filling the ampul afterthe stopper is in position, and wherein in the finished ampul the fluid contained in the ampul and the stopperare hermetically sealed within the ampul.

\Vhat I claim is:

1. An ampul comprising a body portion I having a stopper therein, said stopper having .both ends comprising a recess therein and having a washer on one face, said washer including a hub portion adapted to be positioned in said recess in said stopper, said hub having therethrough an aperture and said aperture being tapered.

2. An ampul adapted for use in a syringe having means or engaging the ampul at a body portion-constricted at one end to form a throat and a closed tip, means adjacent the narrow portion of said constricted throat toweaken it and make the tip bodily removable from said ampul by breaking, the opposite end of said body portion being constricted to form a tapered neck portion, said neck terminating in a closed tip and means adjacent said neck body portion to act as a for weakening it to make the tip readily removable by breaking, a resilient collar surrounding a portion of said tapered neck, said collar being positioned on said neck adj aeent to said weakening means, a stopper in said body portion adjacent said constricted throat, said stop er having engagement with the inner sur ace of said body portion to form a fluid tight seal between said ampul and said stopper, said constricted throat and said tapered neck being adapted to be engaged by the syringe to hold the ampul therein.

3. An ampul comprising a body portion having a stopper therein, said body portion being constricted at one end to form a tapered neck portion, a resilient collar arranged on said tapered neck, said stopper having engagement with the inner surface of said body portion to form a seal between said am 111 and said stopper said stopper being a apted to be moved within said body portion to act as a piston to expel the contents of said ampul out through said previously mentioned neck after said tip has been removed from said ampul, said stopper having a recess therein and having a washer on one face, said washer including a hub portion adapted to be positioned in said recess in said stopper.

4. An ampul comprising a body portion constricted at one end to form a throat and a closed tip, means adjacent the narrow portion of said constricted throat to weaken it and make the tip readily removable from said ampul by breaking, the opposite end of said body portion being constricted to forma tapered neck portion, said neck terminating in a closed tip and means adjacent said neck for weakening it to make the tip readily removable by breaking, a resilient collar surrounding a portion of said tapered neck, said collar being positioned on said neck between said weakening means and said neck, a stopper in said body portion adjacent said constricted throat, said stopper having tight engagement with the inner surface of said body portion to form a fluid tight seal between said ampul and said stopper, said stopper being adapted to be forcibly moved within said piston to expel the contents of said ampul out through said neck after both of said previously mentioned closed tips have been removed from said ampul, said stopper having a recess therein and having a washer on its face adjacent the constricted throat, said washer including a hub portion adapted to be positioned in said recess in said stopper, said hub having an aperture therethrough and said aperture being tapered, said stopper having a concave recess in its opposite face whereby when said stopper is actuated as a piston to expel the contents of said ampul the outer peripheral edges of said face will be forced by the pressure into tight engagement with the interior of said said neck terminating 1n a tip,

body portion, thereby forming a fluid tight joint between said stopper and said body portion.

a throat to be engaged by one portion of the syringe, a stopportion adjacent to said constricted portion, the opposite end of said engaged by another portion both ends of the ampul being provided With closed tips having weakened portions.

6. n ampul adapted for use in a syringe having means for engaging the ampul at both ends, said ampul comprising a hollow body constricted at the rear end to form a throat to be engaged by one portion of the syringe,

of the syringe,

a movable stopper in said body portion adjaoent to said constricted portion, thefront end of said body portion being tapered and adapted to be engaged by another portion of the syringe, said front end of the ampul being provided With a closed tip having Weakened portions.

embedded in said stopper, said washer having a recess therein, said recess being adapted to receive the syringe plunger.

In testimony whereof, I hereunto afiiX my signature.

ARTHUR E. SMITH

Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US5196001 *Mar 5, 1991Mar 23, 1993Ti KaoDevices and methods for preparing pharmaceutical solutions
US5213860 *Oct 31, 1990May 25, 1993Confab Guy Lamarre Inc.Plastic ampul
US7032590 *Jan 5, 2004Apr 25, 2006Aerogen, Inc.Fluid filled ampoules and methods for their use in aerosolizers
EP0458337A1 *May 23, 1991Nov 27, 1991Spacelabs, Inc.Ampule having a fracturing outlet end, a swellable piston and a breakable end for gaining access to the piston
EP1370316A1 *Mar 19, 2002Dec 17, 2003AeroGen, Inc.Fluid filled ampoules and methods for their use in aerosolizers
WO1992006664A1 *Oct 18, 1991Apr 30, 1992Confab Guy Lamarre IncPlastic ampul
WO1998013084A1 *Sep 25, 1997Apr 2, 1998Abbott LabPharmaceutical ampul
Classifications
U.S. Classification604/403
International ClassificationA61J1/06
Cooperative ClassificationA61J1/065
European ClassificationA61J1/06C