|Publication number||US20050143651 A1|
|Application number||US 11/068,342|
|Publication date||Jun 30, 2005|
|Filing date||Feb 28, 2005|
|Priority date||Aug 19, 2002|
|Also published as||EP1391181A1, EP1913893A2, EP1913893A3, EP1913893B1, US6892090, US20040034300|
|Publication number||068342, 11068342, US 2005/0143651 A1, US 2005/143651 A1, US 20050143651 A1, US 20050143651A1, US 2005143651 A1, US 2005143651A1, US-A1-20050143651, US-A1-2005143651, US2005/0143651A1, US2005/143651A1, US20050143651 A1, US20050143651A1, US2005143651 A1, US2005143651A1|
|Inventors||Laurent Verard, Paul Kessman, Mark Hunter|
|Original Assignee||Laurent Verard, Paul Kessman, Mark Hunter|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (105), Non-Patent Citations (1), Referenced by (37), Classifications (19), Legal Events (1)|
|External Links: USPTO, USPTO Assignment, Espacenet|
This application is a continuation of U.S. patent application Ser. No. 10/223,847 filed on Aug. 19, 2002. The disclosure of the above application is incorporated herein by reference.
The present teachings relates generally to surgical instrument navigation systems and, more particularly, to a system that visually simulates a virtual volumetric scene of a body cavity from a point of view of a surgical instrument residing in a patient.
Precise imaging of portions of the anatomy is an increasingly important technique in the medical and surgical fields. In order to lessen the trauma to a patient caused by invasive surgery, techniques have been developed for performing surgical procedures within the body through small incisions with minimal invasion. These procedures generally require the surgeon to operate on portions of the anatomy that are not directly visible, or can be seen only with difficulty. Furthermore, some parts of the body contain extremely complex or small structures and it is necessary to enhance the visibility of these structures to enable the surgeon to perform more delicate procedures. In addition, planning such procedures required the evaluation of the location and orientation of these structures within the body in order to determine the optimal surgical trajectory.
Endoscopy is one commonly employed technique for visualizing internal regions of interest within a patient. Flexible endoscopes enable surgeons to visually inspect a region prior to or during surgery. However, flexible endoscopes are relatively expensive, limited in flexibility due to construction and obscured by blood and other biological materials.
Therefore, it is desirable to provide a cost effective alternative technique for visualizing an internal regions of interest within a patient.
A surgical instrument navigation system is provided that visually simulates a virtual volumetric scene of a body cavity of a patient from a point of view of a surgical instrument residing in the patient. The surgical instrument navigation system generally includes: a surgical instrument, such as a guide wire or catheter; a tracking subsystem that captures real-time position data indicative of the position (location and/or orientation) of the surgical instrument; a data processor which is operable to render a volumetric image of the internal region of interest from a point of view of the surgical instrument; and a display which is operable to display the volumetric image of the patient. The surgical instrument navigation system may also include an imaging device which is operable to capture 2D and/or 3D volumetric scan data representative of an internal region of interest within a given patient.
For a more complete understanding of the present teachings, reference may be made to the following specification and to the accompanying drawings.
The surgical instrument 12 is preferably a relatively inexpensive, flexible and/or steerable catheter that may be of a disposable type. The surgical instrument 12 is modified to include one or more tracking sensors that are detectable by the tracking subsystem 20. It is readily understood that other types of surgical instruments (e.g., a guide wire, a pointer probe, a stent, a seed, an implant, an endoscope, etc.) are also within the scope of the present teachings. It is also envisioned that at least some of these surgical instruments may be wireless or have wireless communications links. It is also envisioned that the surgical instruments may encompass medical devices which are used for exploratory purposes, testing purposes or other types of medical procedures.
A dynamic reference frame 19 is attached to the patient proximate to the region of interest within the patient 13. To the extent that the region of interest is a vessel or a cavity within the patient, it is readily understood that the dynamic reference frame 19 may be placed within the patient 13. To determine its location, the dynamic reference frame 19 is also modified to include tracking sensors detectable by the tracking subsystem 20. The tracking subsystem 20 is operable to determine position data for the dynamic reference frame 19 as further described below.
The volumetric scan data is then registered as shown at 34. Registration of the dynamic reference frame 19 generally relates information in the volumetric scan data to the region of interest associated with the patient. This process is referred to as registering image space to patient space. Often, the image space must also be registered to another image space. Registration is accomplished through knowledge of the coordinate vectors of at least three non-collinear points in the image space and the patient space.
Registration for image guided surgery can be completed by different known techniques. First, point-to-point registration is accomplished by identifying points in an image space and then touching the same points in patient space. These points are generally anatomical landmarks that are easily identifiable on the patient. Second, surface registration involves the user's generation of a surface in patient space by either selecting multiple points or scanning, and then accepting the best fit to that surface in image space by iteratively calculating with the data processor until a surface match is identified. Third, repeat fixation devices entail the user repeatedly removing and replacing a device (i.e., dynamic reference frame, etc.) in known relation to the patient or image fiducials of the patient. Fourth, automatic registration by first attaching the dynamic reference frame to the patient prior to acquiring image data. It is envisioned that other known registration procedures are also within the scope of the present teachings, such as that disclosed in U.S. Ser. No. 09/274,972, filed on Mar. 23, 1999, entitled “NAVIGATIONAL GUIDANCE VIA COMPUTER-ASSISTED FLUOROSCOPIC IMAGING”, which is hereby incorporated by reference.
During surgery, the surgical instrument 12 is directed by the surgeon to the region of interest within the patient 13. The tracking subsystem 20 preferably employs electromagnetic sensing to capture position data 37 indicative of the location and/or orientation of the surgical instrument 12 within the patient. The tracking subsystem 20 may be defined as a localizing device 22 and one or more electromagnetic sensors 24 may be integrated into the items of interest, such as the surgical instrument 12. In one embodiment, the localizing device 22 is comprised of three or more field generators (transmitters) mounted at known locations on a plane surface and the electro-magnetic sensor (receivers) 24 is further defined as a single coil of wire. The positioning of the field generators (transmitter), and the sensors (receivers) may also be reversed, such that the generators are associated with the surgical instrument 12 and the receivers are positioned elsewhere. Although not limited thereto, the localizing device 22 may be affixed to an underneath side of the operating table that supports the patient.
In operation, the field generators generate magnetic fields which are detected by the sensor. By measuring the magnetic fields generated by each field generator at the sensor, the location and orientation of the sensor may be computed, thereby determining position data for the surgical instrument 12. Although not limited thereto, exemplary electromagnetic tracking subsystems are further described in U.S. Pat. Nos. 5,913,820; 5,592,939; and 6,374,134 which are incorporated herein by reference. In addition, it is envisioned that other types of position tracking devices are also within the scope of the present teachings. For instance, non line-of-sight tracking subsystem 20 may be based on sonic emissions or radio frequency emissions. In another instance, a rigid surgical instrument, such as a rigid endoscope may be tracked using a line-of-sight optical-based tracking subsystem (i.e., LED's, passive markers, reflective markers, etc).
Position data such as location and/or orientation data from the tracking subsystem 20 is in turn relayed to the data processor 16. The data processor 16 is adapted to receive position/orientation data from the tracking subsystem 20 and operable to render a volumetric perspective image and/or a surface rendered image of the region of interest. The volumetric perspective and/or surface image is rendered 36 from the scan data 32 using rendering techniques well known in the art. The image data may be further manipulated 38 based on the position/orientation data for the surgical instrument 12 received from tracking subsystem 20. Specifically, the volumetric perspective or surface rendered image is rendered from a point of view which relates to position of the surgical instrument 12. For instance, at least one electromagnetic sensor 24 may be positioned at the tip of the surgical instrument 12, such that the image is rendered from a leading point on the surgical instrument. In this way, the surgical instrument navigation system 10 according to various embodiments is able, for example, to visually simulate a virtual volumetric scene of an internal cavity from the point of view of the surgical instrument 12 residing in the cavity without the use of an endoscope. It is readily understood that tracking two or more electromagnetic sensors 24 which are embedded in the surgical instrument 12 enables orientation of the surgical instrument 12 to be determined by the system 10.
As the surgical instrument 12 is moved by the surgeon within the region of interest, its position and orientation are tracked and reported on a real-time basis by the tracking subsystem 20. The volumetric perspective image may then be updated by manipulating 38 the rendered image data 36 based on the position of the surgical instrument 12. The manipulated volumetric perspective image is displayed 40 on a display device 18 associated with the data processor 16. The display 18 is preferably located such that it can be easily viewed by the surgeon during the medical procedure. In one embodiment, the display 18 may be further defined as a heads-up display or any other appropriate display. The image may also be stored by data processor 16 for later playback, should this be desired.
It is envisioned that the primary perspective image 38 of the region of interest may be supplemented by other secondary images. For instance, known image processing techniques may be employed to generate various multi-planar images of the region of interest. Alternatively, images may be generated from different view points as specified by a user 39, including views from outside of the vessel or cavity or views that enable the user to see through the walls of the vessel using different shading or opacity. In another instance, the location data of the surgical instrument may be saved and played back in a movie format. It is envisioned that these various secondary images may be displayed simultaneously with or in place of the primary perspective image.
In addition, the surgical instrument 12 may be used to generate real-time maps corresponding to an internal path traveled by the surgical instrument or an external boundary of an internal cavity. Real-time maps are generated by continuously recording the position of the instrument's localized tip and its full extent. A real-time map is generated by the outermost extent of the instrument's position and minimum extrapolated curvature as is known in the art. The map may be continuously updated as the instrument is moved within the patient, thereby creating a path or a volume representing the internal boundary of the cavity. It is envisioned that the map may be displayed in a wire frame form, as a shaded surface or other three-dimensional computer display modality independent from or superimposed on the volumetric perspective image 38 of the region of interest. It is further envisioned that the map may include data collected from a sensor embedded into the surgical instrument, such as pressure data, temperature data or electro-physiological data. In this case, the map may be color coded to represent the collected data.
To eliminate the flutter of the indicia on the displayed image 40, position data for the surgical instrument 12 is acquired at a repetitive point within each cycle of either the cardiac cycle or the respiratory cycle of the patient. As described above, the imaging device 14 is used to capture volumetric scan data 42 representative of an internal region of interest within a given patient. A secondary image may then be rendered 44 from the volumetric scan data by the data processor 16.
In order to synchronize the acquisition of position data for the surgical instrument 12, the surgical instrument navigation system 10 may further include a timing signal generator 26. The timing signal generator 26 is operable to generate and transmit a timing signal 46 that correlates to at least one of (or both) the cardiac cycle or the respiratory cycle of the patient 13. For a patient having a consistent rhythmic cycle, the timing signal might be in the form of a periodic clock signal. Alternatively, the timing signal may be derived from an electrocardiogram signal from the patient 13. One skilled in the art will readily recognize other techniques for deriving a timing signal that correlate to at least one of the cardiac or respiratory cycle or other anatomical cycle of the patient.
As described above, the indicia of the surgical instrument 12 tracks the movement of the surgical instrument 12 as it is moved by the surgeon within the patient 13. Rather than display the indicia of the surgical instrument 12 on a real-time basis, the display of the indicia of the surgical instrument 12 is periodically updated 48 based on the timing signal from the timing signal generator 26. In one exemplary embodiment, the timing generator 26 is electrically connected to the tracking subsystem 20. The tracking subsystem 20 is in turn operable to report position data for the surgical instrument 12 in response to a timing signal received from the timing signal generator 26. The position of the indicia of the surgical instrument 12 is then updated 50 on the display of the image data. It is readily understood that other techniques for synchronizing the display of an indicia of the surgical instrument 12 based on the timing signal are within the scope of the present teachings, thereby eliminating any flutter or jitter which may appear on the displayed image 52. It is also envisioned that a path (or projected path) of the surgical instrument 12 may also be illustrated on the displayed image data 52.
According to various embodiments the surgical instrument navigation system 10 may be further adapted to display four-dimensional image data for a region of interest as shown in
In order to synchronize the display of the volumetric perspective view in real-time with the cardiac or respiratory cycle of the patient, the data processor 16 is adapted to receive a timing signal from the timing signal generator 26. As described above, the timing signal generator 26 is operable to generate and transmit a timing signal that correlates to either the cardiac cycle or the respiratory cycle of the patient 13. In this way, the volumetric perspective image may be synchronized 66 with the cardiac or respiratory cycle of the patient 13. The synchronized image 66 is then displayed 68 on the display 18 of the system. The four-dimensional synchronized image may be either (or both of) the primary image rendered from the point of view of the surgical instrument or the secondary image depicting the indicia of the position of the surgical instrument 12 within the patient 13. It is readily understood that the synchronization process is also applicable to two-dimensional image data acquire over time.
To enhance visualization and refine accuracy of the displayed image data, the surgical navigation system can use prior knowledge such as the segmented vessel structure to compensate for error in the tracking subsystem or for inaccuracies caused by an anatomical shift occurring since acquisition of scan data. For instance, it is known that the surgical instrument 12 being localized is located within a given vessel and, therefore should be displayed within the vessel. Statistical methods can be used to determine the most likely location within the vessel with respect to the reported location and then compensate so the display accurately represents the instrument 12 within the center of the vessel. The center of the vessel can be found by segmenting the vessels from the three-dimensional datasets and using commonly known imaging techniques to define the centerline of the vessel tree. Statistical methods may also be used to determine if the surgical instrument 12 has potentially punctured the vessel. This can be done by determining the reported location is too far from the centerline or the trajectory of the path traveled is greater than a certain angle (worse case 90 degrees) with respect to the vessel. Reporting this type of trajectory (error) is very important to the clinicians. The tracking along the center of the vessel may also be further refined by correcting for motion of the respiratory or cardiac cycle, as described above.
The surgical instrument navigation system according to various embodiments may also incorporate atlas maps. It is envisioned that three-dimensional or four-dimensional atlas maps may be registered with patient specific scan data or generic anatomical models. Atlas maps may contain kinematic information (e.g., heart models) that can be synchronized with four-dimensional image data, thereby supplementing the real-time information. In addition, the kinematic information may be combined with localization information from several instruments to provide a complete four-dimensional model of organ motion. The atlas maps may also be used to localize bones or soft tissue which can assist in determining placement and location of implants.
While the teachings has been described in its presently preferred form, it will be understood that the teachings is capable of modification without departing from the spirit of the teachings as set forth in the appended claims.
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|International Classification||A61B17/00, A61B19/00|
|Cooperative Classification||A61B19/50, A61B19/5244, A61B19/52, A61B2019/5295, A61B2019/505, A61B19/5212, A61B2019/501, A61B2019/5291, A61B2019/566, A61B2019/5255, A61B2017/00703, A61B2019/5251, A61B2019/507, A61B2019/5272|
|European Classification||A61B19/52H12, A61B19/52|
|Jun 2, 2014||AS||Assignment|
Owner name: SURGICAL NAVIGATION TECHNOLOGIES, INC., COLORADO
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:VERARD, LAURENT;KESSMAN, PAUL;HUNTER, MARK;REEL/FRAME:033010/0373
Effective date: 20020814
Owner name: MEDTRONIC NAVIGATION, INC., COLORADO
Free format text: CHANGE OF NAME;ASSIGNOR:SURGICAL NAVIGATION TECHNOLOGIES, INC.;REEL/FRAME:033075/0772
Effective date: 20041220