US20070087094A1 - Process for improving the durability of, and/or stabilizing, microbially perishable products - Google Patents
Process for improving the durability of, and/or stabilizing, microbially perishable products Download PDFInfo
- Publication number
- US20070087094A1 US20070087094A1 US11/522,667 US52266706A US2007087094A1 US 20070087094 A1 US20070087094 A1 US 20070087094A1 US 52266706 A US52266706 A US 52266706A US 2007087094 A1 US2007087094 A1 US 2007087094A1
- Authority
- US
- United States
- Prior art keywords
- gras
- alcohol
- acid
- aldehyde
- acetate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 117
- 230000008569 process Effects 0.000 title claims abstract description 89
- 230000000087 stabilizing effect Effects 0.000 title abstract description 7
- 239000000463 material Substances 0.000 claims abstract description 15
- 238000004806 packaging method and process Methods 0.000 claims abstract description 12
- 238000004519 manufacturing process Methods 0.000 claims abstract description 10
- 238000012545 processing Methods 0.000 claims abstract description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 201
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 134
- 239000002253 acid Substances 0.000 claims description 107
- 150000001299 aldehydes Chemical class 0.000 claims description 98
- 238000005520 cutting process Methods 0.000 claims description 91
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 64
- 229940022663 acetate Drugs 0.000 claims description 64
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 57
- 150000003505 terpenes Chemical class 0.000 claims description 49
- 235000007586 terpenes Nutrition 0.000 claims description 49
- 150000002148 esters Chemical class 0.000 claims description 48
- 150000001241 acetals Chemical class 0.000 claims description 38
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 claims description 37
- 230000003641 microbiacidal effect Effects 0.000 claims description 24
- 238000005507 spraying Methods 0.000 claims description 23
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 21
- 239000000796 flavoring agent Substances 0.000 claims description 21
- ZRSNZINYAWTAHE-UHFFFAOYSA-N p-methoxybenzaldehyde Chemical compound COC1=CC=C(C=O)C=C1 ZRSNZINYAWTAHE-UHFFFAOYSA-N 0.000 claims description 19
- -1 rhodinol Chemical compound 0.000 claims description 17
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 claims description 16
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 claims description 15
- 150000001298 alcohols Chemical class 0.000 claims description 14
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 14
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 14
- 235000013824 polyphenols Nutrition 0.000 claims description 14
- ROWKJAVDOGWPAT-UHFFFAOYSA-N Acetoin Chemical compound CC(O)C(C)=O ROWKJAVDOGWPAT-UHFFFAOYSA-N 0.000 claims description 12
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims description 12
- 235000021474 generally recognized As safe (food) Nutrition 0.000 claims description 11
- 235000021473 generally recognized as safe (food ingredients) Nutrition 0.000 claims description 11
- SCCDQYPEOIRVGX-UHFFFAOYSA-N Acetyleugenol Chemical compound COC1=CC(CC=C)=CC=C1OC(C)=O SCCDQYPEOIRVGX-UHFFFAOYSA-N 0.000 claims description 10
- NBBJYMSMWIIQGU-UHFFFAOYSA-N Propionic aldehyde Chemical compound CCC=O NBBJYMSMWIIQGU-UHFFFAOYSA-N 0.000 claims description 10
- RDOXTESZEPMUJZ-UHFFFAOYSA-N anisole Chemical compound COC1=CC=CC=C1 RDOXTESZEPMUJZ-UHFFFAOYSA-N 0.000 claims description 10
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 10
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 10
- ZFMSMUAANRJZFM-UHFFFAOYSA-N Estragole Chemical compound COC1=CC=C(CC=C)C=C1 ZFMSMUAANRJZFM-UHFFFAOYSA-N 0.000 claims description 9
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 9
- JARKCYVAAOWBJS-UHFFFAOYSA-N hexanal Chemical compound CCCCCC=O JARKCYVAAOWBJS-UHFFFAOYSA-N 0.000 claims description 9
- BBMCTIGTTCKYKF-UHFFFAOYSA-N 1-heptanol Chemical compound CCCCCCCO BBMCTIGTTCKYKF-UHFFFAOYSA-N 0.000 claims description 8
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 8
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 claims description 8
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 claims description 8
- FXHGMKSSBGDXIY-UHFFFAOYSA-N heptanal Chemical compound CCCCCCC=O FXHGMKSSBGDXIY-UHFFFAOYSA-N 0.000 claims description 8
- 235000001510 limonene Nutrition 0.000 claims description 8
- 229940087305 limonene Drugs 0.000 claims description 8
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 claims description 8
- RUMOYJJNUMEFDD-UHFFFAOYSA-N perillyl aldehyde Chemical compound CC(=C)C1CCC(C=O)=CC1 RUMOYJJNUMEFDD-UHFFFAOYSA-N 0.000 claims description 8
- 150000002989 phenols Chemical class 0.000 claims description 8
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims description 8
- OOCCDEMITAIZTP-QPJJXVBHSA-N (E)-cinnamyl alcohol Chemical compound OC\C=C\C1=CC=CC=C1 OOCCDEMITAIZTP-QPJJXVBHSA-N 0.000 claims description 7
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 7
- 241000723346 Cinnamomum camphora Species 0.000 claims description 7
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 7
- 229930008380 camphor Natural products 0.000 claims description 7
- 229960000846 camphor Drugs 0.000 claims description 7
- HFJRKMMYBMWEAD-UHFFFAOYSA-N dodecanal Chemical compound CCCCCCCCCCCC=O HFJRKMMYBMWEAD-UHFFFAOYSA-N 0.000 claims description 7
- OIGWAXDAPKFNCQ-UHFFFAOYSA-N 4-isopropylbenzyl alcohol Chemical compound CC(C)C1=CC=C(CO)C=C1 OIGWAXDAPKFNCQ-UHFFFAOYSA-N 0.000 claims description 6
- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 claims description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 6
- 239000005844 Thymol Substances 0.000 claims description 6
- QUKGYYKBILRGFE-UHFFFAOYSA-N benzyl acetate Chemical compound CC(=O)OCC1=CC=CC=C1 QUKGYYKBILRGFE-UHFFFAOYSA-N 0.000 claims description 6
- NEHNMFOYXAPHSD-UHFFFAOYSA-N citronellal Chemical compound O=CCC(C)CCC=C(C)C NEHNMFOYXAPHSD-UHFFFAOYSA-N 0.000 claims description 6
- WTWBUQJHJGUZCY-UHFFFAOYSA-N cuminaldehyde Chemical compound CC(C)C1=CC=C(C=O)C=C1 WTWBUQJHJGUZCY-UHFFFAOYSA-N 0.000 claims description 6
- MWKFXSUHUHTGQN-UHFFFAOYSA-N decan-1-ol Chemical compound CCCCCCCCCCO MWKFXSUHUHTGQN-UHFFFAOYSA-N 0.000 claims description 6
- ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 claims description 6
- 230000006872 improvement Effects 0.000 claims description 6
- MLFHJEHSLIIPHL-UHFFFAOYSA-N isoamyl acetate Chemical compound CC(C)CCOC(C)=O MLFHJEHSLIIPHL-UHFFFAOYSA-N 0.000 claims description 6
- PHTQWCKDNZKARW-UHFFFAOYSA-N isoamylol Chemical compound CC(C)CCO PHTQWCKDNZKARW-UHFFFAOYSA-N 0.000 claims description 6
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims description 6
- UWKAYLJWKGQEPM-LBPRGKRZSA-N linalyl acetate Chemical compound CC(C)=CCC[C@](C)(C=C)OC(C)=O UWKAYLJWKGQEPM-LBPRGKRZSA-N 0.000 claims description 6
- ZWRUINPWMLAQRD-UHFFFAOYSA-N nonan-1-ol Chemical compound CCCCCCCCCO ZWRUINPWMLAQRD-UHFFFAOYSA-N 0.000 claims description 6
- GYHFUZHODSMOHU-UHFFFAOYSA-N nonanal Chemical compound CCCCCCCCC=O GYHFUZHODSMOHU-UHFFFAOYSA-N 0.000 claims description 6
- FBUKVWPVBMHYJY-UHFFFAOYSA-N nonanoic acid Chemical compound CCCCCCCCC(O)=O FBUKVWPVBMHYJY-UHFFFAOYSA-N 0.000 claims description 6
- NUJGJRNETVAIRJ-UHFFFAOYSA-N octanal Chemical compound CCCCCCCC=O NUJGJRNETVAIRJ-UHFFFAOYSA-N 0.000 claims description 6
- SCVFZCLFOSHCOH-UHFFFAOYSA-M potassium acetate Chemical compound [K+].CC([O-])=O SCVFZCLFOSHCOH-UHFFFAOYSA-M 0.000 claims description 6
- 229960000790 thymol Drugs 0.000 claims description 6
- RUVINXPYWBROJD-ONEGZZNKSA-N trans-anethole Chemical compound COC1=CC=C(\C=C\C)C=C1 RUVINXPYWBROJD-ONEGZZNKSA-N 0.000 claims description 6
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 claims description 6
- MSHFRERJPWKJFX-UHFFFAOYSA-N 4-Methoxybenzyl alcohol Chemical compound COC1=CC=C(CO)C=C1 MSHFRERJPWKJFX-UHFFFAOYSA-N 0.000 claims description 5
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims description 5
- GFAZHVHNLUBROE-UHFFFAOYSA-N hydroxymethyl propionaldehyde Natural products CCC(=O)CO GFAZHVHNLUBROE-UHFFFAOYSA-N 0.000 claims description 5
- 239000004310 lactic acid Substances 0.000 claims description 5
- 235000014655 lactic acid Nutrition 0.000 claims description 5
- UZKWTJUDCOPSNM-UHFFFAOYSA-N methoxybenzene Substances CCCCOC=C UZKWTJUDCOPSNM-UHFFFAOYSA-N 0.000 claims description 5
- LCPDWSOZIOUXRV-UHFFFAOYSA-N phenoxyacetic acid Chemical compound OC(=O)COC1=CC=CC=C1 LCPDWSOZIOUXRV-UHFFFAOYSA-N 0.000 claims description 5
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 claims description 4
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 claims description 4
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 claims description 4
- SWTCCCJQNPGXLQ-UHFFFAOYSA-N 1-(1-butoxyethoxy)butane Chemical compound CCCCOC(C)OCCCC SWTCCCJQNPGXLQ-UHFFFAOYSA-N 0.000 claims description 4
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 claims description 4
- KBPLFHHGFOOTCA-UHFFFAOYSA-N 1-Octanol Chemical compound CCCCCCCCO KBPLFHHGFOOTCA-UHFFFAOYSA-N 0.000 claims description 4
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 claims description 4
- 239000001263 FEMA 3042 Substances 0.000 claims description 4
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 claims description 4
- ZYEMGPIYFIJGTP-UHFFFAOYSA-N O-methyleugenol Chemical compound COC1=CC=C(CC=C)C=C1OC ZYEMGPIYFIJGTP-UHFFFAOYSA-N 0.000 claims description 4
- IWYDHOAUDWTVEP-UHFFFAOYSA-N R-2-phenyl-2-hydroxyacetic acid Natural products OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 claims description 4
- 150000001242 acetic acid derivatives Chemical class 0.000 claims description 4
- 150000007513 acids Chemical class 0.000 claims description 4
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims description 4
- OOCCDEMITAIZTP-UHFFFAOYSA-N allylic benzylic alcohol Natural products OCC=CC1=CC=CC=C1 OOCCDEMITAIZTP-UHFFFAOYSA-N 0.000 claims description 4
- IGODOXYLBBXFDW-UHFFFAOYSA-N alpha-Terpinyl acetate Chemical compound CC(=O)OC(C)(C)C1CCC(C)=CC1 IGODOXYLBBXFDW-UHFFFAOYSA-N 0.000 claims description 4
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 claims description 4
- DKPFZGUDAPQIHT-UHFFFAOYSA-N butyl acetate Chemical compound CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 claims description 4
- 229940043350 citral Drugs 0.000 claims description 4
- 235000000484 citronellol Nutrition 0.000 claims description 4
- JOZKFWLRHCDGJA-UHFFFAOYSA-N citronellol acetate Chemical compound CC(=O)OCCC(C)CCC=C(C)C JOZKFWLRHCDGJA-UHFFFAOYSA-N 0.000 claims description 4
- 238000004140 cleaning Methods 0.000 claims description 4
- KSMVZQYAVGTKIV-UHFFFAOYSA-N decanal Chemical compound CCCCCCCCCC=O KSMVZQYAVGTKIV-UHFFFAOYSA-N 0.000 claims description 4
- CBOQJANXLMLOSS-UHFFFAOYSA-N ethyl vanillin Chemical compound CCOC1=CC(C=O)=CC=C1O CBOQJANXLMLOSS-UHFFFAOYSA-N 0.000 claims description 4
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims description 4
- 239000001530 fumaric acid Substances 0.000 claims description 4
- 235000011087 fumaric acid Nutrition 0.000 claims description 4
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 claims description 4
- 239000001087 glyceryl triacetate Substances 0.000 claims description 4
- 235000013773 glyceryl triacetate Nutrition 0.000 claims description 4
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims description 4
- 229930007744 linalool Natural products 0.000 claims description 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 claims description 4
- YLYBTZIQSIBWLI-UHFFFAOYSA-N octyl acetate Chemical compound CCCCCCCCOC(C)=O YLYBTZIQSIBWLI-UHFFFAOYSA-N 0.000 claims description 4
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 claims description 4
- MDHYEMXUFSJLGV-UHFFFAOYSA-N phenethyl acetate Chemical compound CC(=O)OCCC1=CC=CC=C1 MDHYEMXUFSJLGV-UHFFFAOYSA-N 0.000 claims description 4
- SATCULPHIDQDRE-UHFFFAOYSA-N piperonal Chemical compound O=CC1=CC=C2OCOC2=C1 SATCULPHIDQDRE-UHFFFAOYSA-N 0.000 claims description 4
- 230000007480 spreading Effects 0.000 claims description 4
- 238000003892 spreading Methods 0.000 claims description 4
- 229940033123 tannic acid Drugs 0.000 claims description 4
- 229920002258 tannic acid Polymers 0.000 claims description 4
- 235000015523 tannic acid Nutrition 0.000 claims description 4
- 239000011975 tartaric acid Substances 0.000 claims description 4
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- 229960001367 tartaric acid Drugs 0.000 claims description 4
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 4
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- NPNUFJAVOOONJE-ZIAGYGMSSA-N β-(E)-Caryophyllene Chemical compound C1CC(C)=CCCC(=C)[C@H]2CC(C)(C)[C@@H]21 NPNUFJAVOOONJE-ZIAGYGMSSA-N 0.000 claims description 4
- FQTLCLSUCSAZDY-UHFFFAOYSA-N (+) E(S) nerolidol Natural products CC(C)=CCCC(C)=CCCC(C)(O)C=C FQTLCLSUCSAZDY-UHFFFAOYSA-N 0.000 claims description 3
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims description 3
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- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 3
- RADIRXJQODWKGQ-HWKANZROSA-N 2-Ethoxy-5-(1-propenyl)phenol Chemical compound CCOC1=CC=C(\C=C\C)C=C1O RADIRXJQODWKGQ-HWKANZROSA-N 0.000 claims description 3
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- YGCZTXZTJXYWCO-UHFFFAOYSA-N 3-phenylpropanal Chemical compound O=CCCC1=CC=CC=C1 YGCZTXZTJXYWCO-UHFFFAOYSA-N 0.000 claims description 3
- FQTLCLSUCSAZDY-ATGUSINASA-N Nerolidol Chemical compound CC(C)=CCC\C(C)=C\CC[C@](C)(O)C=C FQTLCLSUCSAZDY-ATGUSINASA-N 0.000 claims description 3
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 claims description 3
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- GWYFCOCPABKNJV-UHFFFAOYSA-N beta-methyl-butyric acid Natural products CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 claims description 3
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims description 3
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- HHTWOMMSBMNRKP-UHFFFAOYSA-N carvacrol Natural products CC(=C)C1=CC=C(C)C(O)=C1 HHTWOMMSBMNRKP-UHFFFAOYSA-N 0.000 claims description 3
- 235000007746 carvacrol Nutrition 0.000 claims description 3
- GTZCVFVGUGFEME-IWQZZHSRSA-N cis-aconitic acid Chemical compound OC(=O)C\C(C(O)=O)=C\C(O)=O GTZCVFVGUGFEME-IWQZZHSRSA-N 0.000 claims description 3
- 229930003633 citronellal Natural products 0.000 claims description 3
- 235000000983 citronellal Nutrition 0.000 claims description 3
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims description 3
- 230000001804 emulsifying effect Effects 0.000 claims description 3
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
- A23B4/00—General methods for preserving meat, sausages, fish or fish products
- A23B4/14—Preserving with chemicals not covered by groups A23B4/02 or A23B4/12
- A23B4/18—Preserving with chemicals not covered by groups A23B4/02 or A23B4/12 in the form of liquids or solids
- A23B4/20—Organic compounds; Microorganisms; Enzymes
- A23B4/22—Microorganisms; Enzymes; Antibiotics
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
- A23B4/00—General methods for preserving meat, sausages, fish or fish products
- A23B4/14—Preserving with chemicals not covered by groups A23B4/02 or A23B4/12
- A23B4/18—Preserving with chemicals not covered by groups A23B4/02 or A23B4/12 in the form of liquids or solids
- A23B4/20—Organic compounds; Microorganisms; Enzymes
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/34635—Antibiotics
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3472—Compounds of undetermined constitution obtained from animals or plants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/90—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in food processing or handling, e.g. food conservation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S426/00—Food or edible material: processes, compositions, and products
- Y10S426/805—Pet food for dog, cat, bird, or fish
Definitions
- the present invention relates to a process for improving the durability of, and/or stabilizing, microbially perishable products, to a process adjuvant for implementing this process, and also to the use of the process adjuvant for impacting the surfaces of microbially perishable products and/or their environment.
- fungi and/or bacteria would be able to multiply in an unhindered manner, at best restricted by refrigeration, on a nutrient medium which was ideal for them.
- Typical examples are the spoilage of bread by moulds, e.g. Aspergillus niger , of meat products (e.g. sausage) by enterobacteria or lactobacilli and the contamination of poultry by salmonellas, among many others.
- fungi including yeast and/or their spores, and also Gram-positive and Gram-negative bacteria, are ubiquitous wherever a sterile environment has not been created by special procedures which are expensive and not applicable industrially for economic reasons, suitable countermeasures have to be taken.
- preservatives which, according to the Codex Alimentarius List of the Food and Agriculture Organization (FAO/WHO Food Standard Programme) are listed, as “synthetic preservatives”, in Division 3 Food Additives Preservatives 3.73 and mainly employed in the form of single chemical substances or combinations of these substances.
- the preservatives which are included in the abovementioned list possess bacteriostatic and/or fungistatic activity and substantially improve durability. However, they are rejected by many consumers since their effects on the health of the consumer are not known and/or harmful influences cannot be excluded, in particular in association with repeated intake over a long period of time.
- thermo inactivation of microorganisms for example by pasteurization.
- Pasteurization means a thermal treatment at from 70 to 85° C. for an exposure time of from 30 to 120 minutes.
- pasteurization substantially improves the durability of products which have been treated in this way, it is nevertheless technically elaborate and consumes a very large amount of energy. Over and above this, the viability of spores is often either not impaired or only impaired to a very limited extent. Furthermore, pasteurization is not applicable to temperature-sensitive products or leads to a not inconsiderable loss of quality, since the “degree of freshness” of the pasteurized product declines, at the very latest, as a result of the second thermization (up to 85° C.) which is often required. In addition, it is precisely the valuable constituents of foodstuffs, cosmetics or pharmaceuticals, for example vitamins, amino acids and many pharmaceutical active compounds, which are thermolabile, so that thermal treatment under the customary conditions of pasteurization is out of the question.
- the object of the invention is, therefore, to provide a process for improving the durability of, and/or stabilizing, microbially perishable products, in which, during the process for preparing, processing or packaging the products, their surfaces and/or their environment, in particular the environmental air and/or the surfaces of the utensils or other materials which come directly or indirectly into contact with the products, are impacted with one or more process adjuvants.
- it is intended, in particular, to make it possible to improve the durability of, and stabilize, foodstuffs, animal feeds, cosmetics, pharmaceuticals and other products which are endangered by spoilage without having to mix synthetic preservatives into these treated substances or use pasteurization at temperatures of from 70 to 85° C.
- the intention is also to achieve a reduction in the quantity of the agents employed for the improvement in durability and the stabilization.
- this object is achieved by a process adjuvant which comprises at least one microbicidally active flavouring substance, preferably at least two flavouring substances.
- the invention furthermore relates to a process adjuvant which is characterized in that it comprises at least one microbicidally active flavouring substance, preferably at least two flavouring substances.
- the present invention also relates to the use of the process adjuvant for impacting the surfaces of microbially perishable products and/or their environment for the purpose of spreading, lubricating, emulsifying, separating, cleansing, spraying, nebulizing, gasifying and cutting.
- flavouring substances which are contained in the novel process adjuvants are exclusively natural or identical-to-nature flavouring substances which are recognized, under FEMA, as being safe (GRAS—generally recognized as safe).
- FEMA GRAS Flavouring Substances List GRAS 3-16 Nos. 2001-3834 (as of 1993), which lists natural and identical-to-nature flavouring substances which are authorized by the American Public Health Authority FDA for use in foodstuffs (FDA Regulation 21 CFR 172.515 for identical-to-nature flavouring substances (Synthetic Flavouring Substances and Adjuvants) and FDA Regulation 21 CFR 182.20 for natural flavouring substances (Natural Flavouring Substances and Adjuvants).
- Flavouring substances which meet these FDA standards can be employed in a “quantum satis” manner, i.e. they may be present in the foodstuff up to the highest concentration at which they still do not impair the smell or taste of the foodstuff to which they have been added.
- the flavouring substances listed under FEMA coincide, to a large extent, with the substances contained in the corresponding European standard COE.
- NAT4 the flavouring substances classified as “NAT4” according to Article V of European Community Directive Flavourings (22.06.88) may also be used provided that they are regarded as being safe in accordance with the abovementioned FEMA GRAS list.
- NAT4 substances are substances which can be declared to be identical-to-nature under certain conditions, for example when the substances are employed in combination with, and as a constituent of, a natural or identical-to-nature flavouring substance.
- novel process adjuvants are that, owing to their constituents being listed in the FEMA GRAS list and being recognized by the US Public Health Authority FDA, which is probably the most critical health authority of all, as being harmless, they can readily be added to foodstuffs in the “quantum satis” concentration range.
- a further particular advantage is that the process adjuvants do not affect the taste and smell of the treated products.
- novel process adjuvants are employed, for example, in the form of lubricants, emulsifiers, washing agents, sprays, nebulizing agents, gas-phase-active agents, heat-transferring agents and also cutting agents or separating agents.
- the process adjuvants may also be employed as additives which are included in the said agents.
- the process adjuvants are not added to the foodstuffs or mixed with them. Rather, it is only the surfaces or cut surfaces of the foodstuffs which are impacted with the process adjuvants. This can take place by the foodstuff surfaces or cut surfaces being impacted directly with the process adjuvants. However, it is also possible to treat the surfaces of utensils, production machines, packaging equipment, transport equipment, packaging materials and the environmental air with the process adjuvant.
- the microbicidal effect of the process adjuvants is seen even when low concentrations are used. Only from 0.01 to 5 g, preferably from 0.05 to 1 g per kg of foodstuff is used when the process adjuvants are impacted. In a preferred embodiment, 0.01 to 1.0 g/kg of process adjuvant per food stuff is used, more preferred 0.01 to 0.5 g/kg, and most preferably 0.05 to 0.5 g/kg. When they are used for the environmental air, only from 0.001 to 10 g are employed, for example, per M3 of air. Indeed, only from 0.000001 g to 0.1 g/cm2 of surface is used for the surfaces of utensils.
- flavouring substances employed in accordance with the invention exert their microbicidal effect is less than 24 hours, preferably less than 12 hours. It is very particularly preferred to select process adjuvants and concentrations such that the time for the microbicidal effect is less than 1 hour, preferably less than 15 minutes.
- the aim of the conventional preservatives is to be active in the foodstuff for as long as possible, i.e. over weeks and months.
- the durability is significantly increased as compared with that of foodstuffs which have been treated in accordance with the state of the art with conventional preservatives or preservation processes.
- the novel process adjuvant comprises flavouring substances which are selected from the group of the alcohols, aldehydes, phenols, acetates, acids, esters, terpenes, acetals, and their physiologically tolerated salts, ethereal oils and plant extracts.
- Acetoin acetylmethylcarbinol
- ethyl alcohol ethanol
- propyl alcohol (1-propanol)
- isopropyl alcohol (2-propanol, isopropanol
- propylene glycol glycerol
- benzyl alcohol n-butyl alcohol (n-propylcarbinol)
- iso-butyl alcohol (2-methyl-1 propanol)
- hexyl alcohol hexanol
- L-menthol octyl alcohol (n-octanol), phenyl ethyl alcohol (2-phenylethanol), cinnamyl alcohol (3-phenyl-2-propen-1-ol), a-methylbenzyl alcohol (1-phenylethanol), heptyl alcohol (heptanol), n-amyl alcohol (1-pentanol), iso-amyl alcohol (3-methyl-1-butanol), anise alcohol (4-me
- Thymol methyleugenol, acetyleugenol, safrole, eugenol, isocugenol, anethole, phenol, methyl chavicol (estragole; 3-(4-methoxyphenyl)-1-propene), carvacrol, ⁇ -bisabolol, fornesol, anisole, (methoxybenzene) and propenylguaethol (5-propenyl-2-ethoxyphenol).
- Isoamyl acetate (3-methyl-1-butyl acetate), benzyl acetate, benzylphenyl acetate, n-butyl acetate, cinnamyl acetate (3-phenylpropenyl acetate), citronellyl acetate, ethyl acetate, eugenol acetate, (acetyleugenol), geranyl acetate, hexyl acetate (hexanyl ethanoate), hydrocinnamyl acetate (3-phenylpropyl acetate), linalyl acetate, octyl acetate, phenylethyl acetate, terpinyl acetate, triacetin (glyceryl triacetate), potassium acetate, sodium acetate, and calcium acetate.
- Camphor, limonene and)i-caryophyRene Camphor, limonene and)i-caryophyRene.
- Oils or extracts containing a high proportion of alcohols balm, coriander, cardamom, eucalyptus;
- Oils or extracts containing a high proportion of phenols oreganum, thyme, rosemary, orange, carnation, fennel, camphor, tangerine, anise, cascarilla, tarragon and allspice;
- flavouring substances Isopropanol and ethanol are not used if the process adjuvant comprises only one of the said flavouring substances. Surprisingly, it has been found that a combination of at least two of the given flavouring substances has a far greater effect than that produced by one single substance.
- flavouring substances listed in the GRAS FEMA list are not water-soluble, i.e. they are hydrophobic. If they are employed in foodstuffs which primarily contain fat, they can be used directly without solvents owing to their lypophilic character. However, the proportion of lypophilic foodstuffs is relatively small. In order to ensure that they can exert their effect in foodstuffs, animal feeds, cosmetics or pharmaceuticals which are in the main hydrophilic, they are preferably employed in combination with a water-soluble solubilizer. In order to do justice to the claim of this invention—to make available process adjuvants which are harmless from the point of health—use is made exclusively of solubilizer-flavouring substances, e.g. alcohols, which are authorized for food stuffs.
- solubilizer-flavouring substances e.g. alcohols
- the process adjuvants are used undiluted and/or in water-soluble dilutions with water and/or solvents (e.g. alcohols) which are authorized for food stuffs and/or in fat-soluble dilutions with vegetable (fatty) oils.
- solvents e.g. alcohols
- the process adjuvant comprises a GRAS flavoring compound that is an alcohol, and an additional different GRAS flavoring compound.
- the additional GRAS flavoring compound is at least 0.001% by weight of the processing adjuvant, more preferably at least 0.01% by weight, and most preferably at least 0.05% by weight.
- the novel process adjuvants preferably comprise less than 50% by weight of ethanol, isopropanol or benzyl alcohol, or of a mixture of these compounds.
- the proportion of the said alcohols is less than 30% by weight, in particular less than 20% by weight.
- Provided process adjuvants are employed which comprise benzyl alcohol and at least one further flavouring substance, the proportion of benzyl alcohol can also be more than 50% by weight.
- the process adjuvants which comprise, for example, only 20% by weight of ethanol or isopropanol in combination with flavour aldehydes and flavour phenols in concentrations which are in the per 1000 range possess a very powerful fungicidal and bactericidal effect; even process adjuvants which comprise 1% by weight of the said water-soluble alcohols in combination with less than 3% of flavour aldehyde and flavour phenol exhibit a 70 to 100% microbicidal effect.
- novel process adjuvants possess surprising microbicidal effects in the production environment or in the production process environment.
- the process adjuvants are used for improving the durability of, and stabilizing, foodstuffs selected from the following group:
- the novel process adjuvant exerts its effect in the environment of the product, for example a foodstuff or animal feed, which is susceptible to spoilage, e.g. on machine parts which are in contact with the product to be worked or processed, or in the air.
- a foodstuff or animal feed which is susceptible to spoilage
- novel process adjuvant is, therefore, that on the one hand it decontaminates in a dependable manner, with its activity against Gram-positive and Gram-negative bacteria, fungi, including yeast, and viruses having been proved, while, on the other hand, it does not constitute any danger for the consumer of the foodstuff since it is completely harmless to this consumer and does not possess any microbicidal, technological after effect in the foodstuff, since the microbicidal activity relates to the production environment, which is freed from contaminating microorganisms by the novel measures.
- the novel process adjuvant can be a lubricant which is used simultaneously for lubrication, for decontamination of the lubricated parts and consequently, indirectly, for stabilizing the durability of the products which are in contact with these parts.
- the process adjuvant can also be an emulsifier, a separating agent or a cleansing agent.
- agents are used for emulsification and/or cleansing and consequently also for decontaminating surfaces, articles, machines, equipment, utensils, cutting surfaces and cutting devices, transport devices and the like.
- the adjuvant can furthermore be used for decontaminating and cleansing foodstuffs, raw materials, cosmetics, pharmaceuticals, paints, paper, cellulose, livestock, poultry, fish and garbage.
- the novel process adjuvant can be a spray.
- a spray enables the decontaminating active compounds to be finely distributed on all machine parts, transport devices, cutting devices, working surfaces, etc., and can simultaneously result in foodstuffs which are packed immediately after the cutting or separating procedure and/or packaging/portioning procedure being stored in a climate which possesses decontaminating and/or durability-stabilizing properties as the result of enclosed spray.
- nebulizable or sprayable embodiments are very economical owing to the comparatively small amounts required.
- the spray can also be blown or sprayed/nebulized into and/or onto packaging, for example packets, cartons or the like, in order thereby to preserve the product which is packed therein for a longer period.
- the sprays can also be nebulized in the production environment (surroundings, refrigeration, ventilation, fresh air) at hygienic weak spots (e.g. cooling sections), in order thereby to reduce the number of organisms without the personnel operating in this environment being harmed.
- hygienic weak spots e.g. cooling sections
- the process adjuvants may also be employed for spraying onto foodstuff surfaces or cut surfaces in order to eliminate or reduce the spoilage causing agents which are present on the foodstuffs.
- these sprays can be employed in transport equipment, stores and coldrooms, and the like.
- the process adjuvant may also be employed by dipping the foodstuff, packaging materials, all machine parts, transport devices, cutting devices, working surfaces, etc., into the process adjuvant.
- the novel process adjuvant is a gas-phase active agent which is used for active decontamination and/or deodorizing in the gas phase in systems, such as packages, waste systems, container systems, transport spaces, storage spaces and the like, which are more or less closed.
- gas-phase active agent which is used for active decontamination and/or deodorizing in the gas phase in systems, such as packages, waste systems, container systems, transport spaces, storage spaces and the like, which are more or less closed.
- the packed goods which are contained, transported or stored in the container, as well as the air and the particular environment, profit from the effect of the gas-phase agent.
- the novel process adjuvant has also proved to be a good heat transferring agent.
- heat-transferring agents are meant cooling agents, heating agents and warming agents which can be used as decontaminating additives in circulating circulatory systems of liquid cooling systems, heating systems and warming systems.
- they are added to aqueous or oily systems to prevent the growth of microorganisms in the liquids in order, for example, to prevent contamination occurring in association with the leakage of refrigeration systems.
- the novel process adjuvant is a cutting agent or separating agent for cutting knives and/or cutting devices of every kind and for all perishable products which are to be cut, in order to prevent contamination of the cutting sites.
- contaminations with Gram-negative or Gram-positive pathogens, moulds, yeasts and other possible spoilage-causing agents often occur at the cutting sites or separation sites of foodstuffs, which contaminations can impair, sometimes substantially, the durability of the cut or separated products and consequently cause both economic damage and damage to health.
- the contaminations are introduced by raw materials, product/raw material residues and personnel and also by machine parts or operationally associated processes or by the air.
- the cut or separated foodstuffs, or the foodstuffs which are to be cut or separated are still either pasteurized or treated technically in order to decontaminate them, and thereby preserve them, or are treated with preservatives.
- a thermal treatment is not possible or admissible in every case and can lead to a diminution in the quality of the product in some circumstances.
- a flanking measure for improving the durability of foodstuffs is the purification or even disinfection of the environment using chemical disinfectants which are subject to the biocide regulation. These substances are more or less poisonous and should not be transferred to foodstuffs.
- chemical disinfection is a discontinuous measure which can, in practice, only be applied to machine parts and to the environment at particular times during production and after whose implementation it is subsequently necessary. to flush with water in order to remove the residual substances.
- the direct and permanent elimination of spoilage-causing agents is not ensured.
- Synthetic polyester wrappings enclosing an introduced nitrogen-containing atmosphere result in even longer durability.
- all these measures are either very costly or can only be employed for expensive special products and special markets and sometimes lead to substantial losses in the quality of the sliced bread, for example as the result of condensate formation in the bread bag, as the result of a bread consistency which is too soft, or as the result of premature drying out. None of these measures solves the real causes of the contamination by the cutting or separating process, which process, by means of the cutting device, for example the cutting blades, introduces both the possible spoilage-causing agents which are present in the environment, and those which are present in a product or on the machine, into the foodstuff and distribute them therein.
- novel cutting agent or separating agent can be employed wherever cutting or separating is taking place on an industrial scale and the material which is being cut can be subject to spoilage by bacteria or fungi or contamination with viruses. While this applies to celluloses and paper, for example, it also applies, in particular to foodstuffs and animal feeds.
- the novel process adjuvant is suitable for cutting or separating bread, baked goods, fish and fish products, potatoes and products based on potatoes, fruit and vegetable and products based on fruit and vegetable, confectionary, starch products, pastas, meat and meat products, cheese products, poultry and poultry products.
- the novel process adjuvant is a cutting agent or separating agent (for example for cutting bread)
- this agent can then be prepared on a customary vegetable oil/fat/wax basis while adding microbicidal process adjuvants which are based on flavouring substances.
- the cutting agent or separating agent (for example for use in the meat products industry) can preferably, according to the invention, consist exclusively of one or more flavouring substances.
- Natural emulsifiers for example lecithins at a concentration of from 1 to 25% by weight, can be added to the vegetable oils, vegetable waxes and vegetable fats, in correspondence with the state of the art.
- emulsifiers are lecithins, citric acid monoglycerides, diacetyl tartaric acid, N-acetylphosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidic acids and phosphatidylcholine.
- novel cutting agent or separating agent is prepared as a water-based emulsion
- vegetable oils, vegetable fats and vegetable waxes having unsaturated and saturated C 16 -C 18 fatty acids which also have a viscosity of from about 10 mPas (20° C.) to about 500 mPas (20° C.) are then used.
- the cutting/separating agent which has been assembled, for example, from the abovementioned fatty acids or oils and emulsifiers, can then be used as a cutting emulsion or separating emulsion (milk).
- the novel cutting agent or separating agent is applied at least to the machine parts which are in contact with the material which is being cut in order to decontaminate these parts.
- the agents are employed in doses of 1-20 g/kg of foodstuff with the dose depending on the cutting or separating device used and the material being cut.
- the cutting/separating agents are usually applied to the cutting or separating devices, for example sprayed onto circular dish wheel cutting machines when slicing bread, which are then used to cut sliced bread, for example.
- parts of the cutting devices for example circular dish knives, band slicers (rotating band-saws), electrical or mechanical knives or knife devices, electrical or mechanical saws or sawing devices, and electrical or mechanical chain saws or devices, are wetted in this context such that the cutting or separating agent can exert a decontaminating or microbicidal effect on the corresponding machine part and also on the surface which results from the cutting or separating.
- the advantageous effect of the novel cutting/ separating agents is expressed in an extended durability of the material which is being cut, for example sliced bread. It is based, not least, on the fact that the cutting and separating agent penetrates the surface of the material which is being cut and also decontaminates tile deeper layers of the cut foodstuff, specifically using the flavouring substances contained in the cutting oil.
- flavouring substances described here also exert a microbicidal effect in the vapour phase, since most flavouring substances volatilize readily. They therefore exert their effect in the so-called environment of the foodstuff, for example in packaging the foodstuff, when the latter is packed, for example, in a film wrapping after the cutting process.
- This process of decontaminating the cut material after the actual cutting procedure can be supported by a mild thermal aftertreatment of the foodstuff without the latter losing any quality in its packaging.
- bread for example, is packed in polyethylene films and then brought, for example by means of microwave treatment, within from 10 seconds to 5 minutes, to a core temperature of between 300 and 50° C., or treated thermally for up to 1 hour at a core temperature of from 30° to 50° C., which reinforces the decontaminating effect of the cutting at separating agent.
- the advantageous effect of the cutting/separating agents can in some cases be substantially increased if the application and cutting or separating techniques are improved, or freshly developed, such that the foodstuff is intensely wetted with cutting or separating agent.
- the circular dish cutting blade was provided with separate slot guides and grooves, thereby rendering possible a more thorough and intense application of cutting or separating agent.
- ethanol and isopropanol are microbicidal in high concentrations (75% by weight to more than 90% by weight).
- additives containing such a high concentration of ethanol or isopropanol are more likely to be undesirable owing, on the one hand, to the dangers in handling them, in particular their ready flammability, and, on the other hand, from considerations of principle, for example with regard to children or former alcoholics.
- the ethanol or isopropanol concentration is reduced to 20% by weight, or less, based on the process adjuvant, there is no longer any detectable bactericidal or fungicidal effect, as is demonstrated in the table below.
- a)-c) investigates the organism number of acid-formers such as lactobacilli.
- the number of organisms was determined beforehand, after an exposure time of 10 minutes (after spraying with HIQProSlice, registered trade mark of Schür in Process GmbH), after cooling and prior to packaging.
- Nutrient medium for the total number of organisms RODAC containing TSA, TW 80 and lecithin.
- the Table demonstrates that the addition of HIQProSlice, even in substantial quantities, has no effect on the extension of durability.
- the HIQProSlice has no preserving effect when added as an additive.
- the table demonstrates that an improvement in durability is obtained by spraying the sausage with 1 g per 1000 g of product.
- the Table demonstrates that an improvement in durability is obtained by spraying the surfaces and utensils.
- a reduction in the number of microorganisms of an RF log of at least two is obtained within 10 minutes by spraying the sausage surface.
- the plates containing the Bacillus spores were incubated at 30° C. for 3 days and then checked for inhibition haloes.
- a small antibiotic plate served as positive control for the Bacillus strain, while an agar sample which was only treated with spores was used as the growth control.
- HIQ Pro Chick was examined, both in the above quantities and as a concentrated, 10% and 1% solution, without protein contact, for an inhibitory effect against Bacillus subtilis .
- This batch was implemented on 2 different days.
- HIQ Pro Chick without protein No inhibitory haloes with 10, 50 and 100 ml sample volumes and 100%, 10% and 1% solution.
- the HIQ Pro Chick sample has any bactericidal or bacteriostatic effect, i.e. any microbiological/technological aftereffect with chicken muscle extract either, in any of the experimental mixtures, even at a 10-fold dosage.
- Process adjuvant for spraying cutting knives, as a cutting agent, and for spraying transport devices using the example of sliced sausage and considering the reduction of spoilage-causing agents (enterobactetia/lactobacilli) on cutting knives, transport devices and cut sausage surfaces, and improvement/extension of durability.
- MB Sample during continuous spraying of the belt and the knife Total no. Spore Date Sample of orgs. Entero Lacto Staph. Yeast Moulds formation Week 1 V ⁇ 10 2 ⁇ 10 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 M ⁇ 10 2 ⁇ 10 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 R ⁇ 10 2 ⁇ 10 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 MB ⁇ 10 2 ⁇ 10 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 ⁇ 10 2 Week 2 V 7.2 * 10 3 ⁇ 10 >3 * 10 6 ⁇ 10 ⁇ 10 ⁇ 10 ⁇ 10 2 M 3.2 * 10 2 ⁇ 10 2 * 10 2 ⁇ 10 ⁇ 10 ⁇ 10 ⁇ 10 2 R 1.4 * 10 3 ⁇ 10 1.5 * ⁇ 10 3 ⁇ 10 ⁇ 10 ⁇ 10 ⁇ 10 2 MB 1.8 * 10 4 ⁇ 10 1.7 *
- the durability of sausage is significantly improved by using the cutting agent which is applied to the cutting devices. At the same time, there is surprisingly good cleaning of the cutting surfaces of the cutting devices. Furthermore, the cuttability of the sausage is improved. The durability is substantially improved despite the high dilution of the substances employed. Outstanding results can be obtained with vegetable oils in dilutions of from 1:10 to 1:100.
- Process adjuvant for cutting by means of spraying on cutting knives (band slicer) and circular dish cutting machine, and spray for spraying the surfaces of the foodstuff, using toast bread as an example and considering the reduction of spoilage-causing agents on the machine parts and bread surfaces and/or cutting surfaces (moulds/ Aspergillus niger ) while at the same time improving/extending durability.
- Fog Without preservative and using the nebulizing agent in the air
- Test E. coli ATCC11229 organisms Staph. aureus ATCC6538 Ps. aeruginosa ATCC15442 C. albicans ATCC10231 A. niger ATCC16404 Cladosporium herbarum (our own isolate) 2. Nutrient CSA (Tryptone Soya Agar Oxoid CM media: 131) CSB (Tryptone Soya Broth Oxoid CM 129) YGC agar (Merck 16000) Tween 80 (Merck) 3. Implementation of the Tests 3.1. In-Vivo Test for Determining the Shortest Durability
- the fungi and bacteria are taken up with a swab (stroke across the grown plate with turning movements) and spread uniformly, e.g. over the cut surface of a sliced bread sample so that a concentration of 10 3 -10 4 spores or microorganisms is achieved per 100 cm 2 .
- test bread samples are packed in plastic bags (polyethylene or polypropylene) and the plastic bags are closed and stored at room temperature in the light.
- the growth of microorganisms on the contaminated bread samples is compared with that on control bread.
- the number of days after which a growth of microorganisms can be recognized with the naked eye for the first time is taken as the shortest durability.
- An exposure time of from 5 min to 1 hour is chosen for organisms such as Staph. aureus, Pseudomonas and E. coli, while an exposure time of 1.6 and 24 hours is chosen for A. niger and C. albicans . During the exposure time, the suspensions are shaken regularly.
- CSB oxoid
- CSB oxoid
- substances which inactivate the flavouring substance(s) which has/have been tested in each case For example, 0.1% by weight of histidine is added for inactivating aldehydes, 1% by weight of Tween 80® is added for inactivating phenols, 0.2% by weight of Tween® is added for inactivating alcohols, and 0.03% by weight of lecithin is added for inactivating acids, esters, inter alia.
- CSA oxoid
- A. niger/C. albicans YGC Agar Merck
- the destruction factor is determined as the reduction factor (RF) in relation to a growth control of 10 5 -10 7 CFU/ml.
- the gas-phase test method is used to determine the destruction factor when using gas-phase-active process adjuvants.
- the determination is carried out in a so-called double petri dish.
- 0.5 ml of the gas-phase-active agent is added to, for example, bread or small urea/formaldehyde foam blocks (0.5′1′3 cm) which are located on an absorbing surface.
- the bread or the small foam blocks are placed in one compartment of a subdivided petri dish.
- a filter paper disc (diameter: 13 mm) which is inoculated with from approx. 10 8 to 10 9 organisms is placed in another compartment of the same petri dish.
- the dish is sealed in an airtight manner and incubated at a temperature of 30° C. for 24 hours.
- the filter paper disc is suspended in 9 ml of CSB and a dilution series is prepared in CSB.
- the tubes are incubated at 30° C. and evaluated. The destruction factor is determined in comparison with the control.
- the gas-phase suspension method is used to carry out a first investigation for bactericidal and/or fungicidal properties.
- melt molten nutrient media corresponding to the particular test microorganism concerned are inoculated with from 10 5 to 10 6 organisms per ml.
- the nutrient media are poured into petri dishes and cooled.
- 80 ml of the agent to be tested (additive or process adjuvant) are loaded onto a filter paper disc (diameter: 13 mm; Schleicher & Schüll, Article 601/2) and four of the filters prepared in this way are distributed uniformly on the surface of a prepared petri dish. The plates are subsequently incubated at 37° C. for 24 hours.
- the preservation test was determined in accordance with USP XXII/NF XVII, US Pharmacopeia, United States Pharmacopeial Convention, Rockville, Md. 20852.
- aureus Anisaldehyde 0.2% by weight 0 3.3 Oreganum oil, 0.04% by weight (Active compound combination 5E) 20% by weight of ethanol 0 3.4 20% by weight of isopropanol 0.5 0.3 20% by weight of ethanol + 5E 5.4 7.7 20% by weight of isopropanol + 5E 5.4 7.7 1% by weight of ethanol 0 0 1% by weight of isopropanol 0 0 1% by weight of ethanol + 5E 0.9 7.7 1% by weight of isopropanol + 5E 0.1 5.5 Growth control log CFU: log CFU: 7.7 5.4
- the durability of sliced bread was investigated a) on bread which was sliced using conventional cutting agents and which was not inoculated with microorganisms, and on bread which was sliced using the novel cutting agent and which was artificially contaminated after having been sliced.
- Durability of the sliced bread in days % by Control Cladosporium Staph. weight bread, herbarum A. niger aureus based on sliced 5 ′ 10 5 CFU/ 2 ′ 10 4 CFU/ 4 ′ 10 4 CFU/ the ready- bread, 100 cm 2 100 cm 2 100-cm 2 Cutting/separating to-use untreated of of of agent agent 20° C. bread 20° C. bread 20° C. bread 20° C.
- the following table shows the durability of sliced bread which, on the one hand, was sliced using conventional cutting oil and, on the other, using cutting/separating agents according to Table 6, and which was not subjected to any thermal aftertreatment, and, subsequently, of such bread which was sliced using novel cutting/separating agents and subsequently subjected to a mild thermal after treatment.
- TABLE 8 Durability of sliced bread in days Bread sliced using a cutting/ Control bread Control bread separating agent according to sliced using sliced using a Table 6 and subjected to a cutting oil cutting/separating thermal aftertreatment without a agent Exposure Core Durability Cutting/separating novel process according to time in temp. in agent adjuvant Table 6 s/min in ° C. days a 3 11 10 s 30° C.
- Example 11 11 Cutting agent 12 Heat/cold transferring agent 13 Emulsifier, separating agent and cleansing agent 14 Lubricant 15 Gas-phase-active agent 16 Nebulizing agent 17 Spray
- the recipe examples consist, by way of example, of individual and/or several flavour function groups combined amongst themselves and/or combined synergistically.
- the process adjuvants are used either undiluted or following dilution with water and/or foodstuff-admissible solvents and/or vegetable (fatty) oils and/or emulsifiers of from 0.01% by weight to 99.99% by weight, preferably in a mixing ratio of from 1:1 to 1:100.
- Process adjuvant Example employed No.: Toast bread Nebulizing agent 16 Cutting agent 11 Spray 17 Fancy cakes and pastries Nebulizing agent 16 Sliced sausage Cutting agent 11 Emulsifier, separating 13 agent, cleansing agent Grilling sausage Spray 17 Boiler water for heating chocolate Heat transferring agent, 12 mass cold transferring agent Conveyor belt Lubricant 14 Waste container Gas-phase-active agent 15
- Example % Function group FDA flavour by weight 1 Alcohol Glycerol 100 2 Alcohol/ Glycerol/ 92 aldehyde hexyl aldehyde 8 3 Alcohol/ Acetoin/ 71 aldehyde/ anisaldehyde/anisole 20 phenol 9 4 Alcohol/ Propyl alcohol/thymol 95 phenol 5 5 Aldehyde- Acetaldehyde/ 84 phenol eugenol 16 6 Alcohol/ Citronellol/ 76 acid tartaric acid 24 7 Alcohol/ Anise 62 aldehyde/ alcohol/hydrocinnamaldehyde/ 28 acid citric acid 10 8 Alcohol/aldehyde/ Glycerol/ 40 phenol/ citral/ 14 acid estragole/ 18 tannic acid 28 9 Aldehyde Perillaldehyde 100 10 Aldehyde/ Perillaldehyde/
- ethanol and benzyl alcohol do not possess any microbiocidal capabilities. In contrast to ethanol (and similarly isopropanol), once having formed appropriate synergisms benzyl alcohol is capable of reducing bacterial growth and the growth of molds.
Abstract
The present invention relates to a process for improving the durability of, and/or stabilizing, microbially perishable products, in which, during the process for preparing, processing or packaging the products, their surfaces and/or their environment, in particular the environmental air and/or the surfaces of the utensils or other materials which come directly or indirectly into contact with the products, are impacted with one or more process adjuvants, the process adjuvant comprising at least one microbicidally active flavouring substance.
Description
- This application is a continuation-in-part application of U.S. application Ser. No. 08/737,655, filed 19 Feb. 1997, entitled “Process for improving the durability of, and/or stabilizing, microbially perishable products”, which is the US National Phase of PCT application PCT/EP96/01364, filed 28 Mar. 1996. This application also claims priority under U.S.C. § 119(a) from German Patent No. 195 12 147.3, filed 31 Mar. 1995. The entire disclosures of all the above identified applications are incorporated by reference herein.
- The present invention relates to a process for improving the durability of, and/or stabilizing, microbially perishable products, to a process adjuvant for implementing this process, and also to the use of the process adjuvant for impacting the surfaces of microbially perishable products and/or their environment.
- Industrially processed foodstuffs, animal feeds, cosmetics, pharmaceuticals and other products which are susceptible to microbial spoilage must keep for a certain period of time, which is not too short, in order, following transport and marketing by the usual routes, to reach the consumer in unspoiled condition. In addition to this, the consumer does not expect the product he has bought to perish immediately after purchase but, on the contrary, that it will be possible to keep it in storage for some days or weeks, depending on the product.
- Without being treated, most foodstuffs and animal feeds would perish within a few days since fungi and/or bacteria would be able to multiply in an unhindered manner, at best restricted by refrigeration, on a nutrient medium which was ideal for them. Typical examples are the spoilage of bread by moulds, e.g. Aspergillus niger, of meat products (e.g. sausage) by enterobacteria or lactobacilli and the contamination of poultry by salmonellas, among many others. Since fungi, including yeast and/or their spores, and also Gram-positive and Gram-negative bacteria, are ubiquitous wherever a sterile environment has not been created by special procedures which are expensive and not applicable industrially for economic reasons, suitable countermeasures have to be taken.
- Conventionally, therefore, foodstuffs, animal feeds, cosmetics, pharmaceuticals, paints, paper and celluloses and other perishable products are preserved using preservatives which, according to the Codex Alimentarius List of the Food and Agriculture Organization (FAO/WHO Food Standard Programme) are listed, as “synthetic preservatives”, in Division 3 Food Additives Preservatives 3.73 and mainly employed in the form of single chemical substances or combinations of these substances.
- The preservatives which are included in the abovementioned list possess bacteriostatic and/or fungistatic activity and substantially improve durability. However, they are rejected by many consumers since their effects on the health of the consumer are not known and/or harmful influences cannot be excluded, in particular in association with repeated intake over a long period of time.
- A particular disadvantage of these preservatives is that they are added to the foodstuff regularly. As a result, relatively high concentrations of these preservatives also enter the human body during consumption. The reactions in the form of allergic diseases which are seen much more frequently nowadays are the consequence.
- An alternative to preservation by adding synthetic preservatives is thermal inactivation of microorganisms, for example by pasteurization. Pasteurization means a thermal treatment at from 70 to 85° C. for an exposure time of from 30 to 120 minutes.
- While pasteurization substantially improves the durability of products which have been treated in this way, it is nevertheless technically elaborate and consumes a very large amount of energy. Over and above this, the viability of spores is often either not impaired or only impaired to a very limited extent. Furthermore, pasteurization is not applicable to temperature-sensitive products or leads to a not inconsiderable loss of quality, since the “degree of freshness” of the pasteurized product declines, at the very latest, as a result of the second thermization (up to 85° C.) which is often required. In addition, it is precisely the valuable constituents of foodstuffs, cosmetics or pharmaceuticals, for example vitamins, amino acids and many pharmaceutical active compounds, which are thermolabile, so that thermal treatment under the customary conditions of pasteurization is out of the question.
- Another possibility for improving durability is to pack the product which is endangered by spoilage under nitrogen or CO2 in an airtight manner, or to supply it in vacuum packs as is the case, for example, with ground coffee. However, these processes are expensive and elaborate and therefore not applicable to many foodstuffs.
- The object of the invention is, therefore, to provide a process for improving the durability of, and/or stabilizing, microbially perishable products, in which, during the process for preparing, processing or packaging the products, their surfaces and/or their environment, in particular the environmental air and/or the surfaces of the utensils or other materials which come directly or indirectly into contact with the products, are impacted with one or more process adjuvants. By these means, it is intended, in particular, to make it possible to improve the durability of, and stabilize, foodstuffs, animal feeds, cosmetics, pharmaceuticals and other products which are endangered by spoilage without having to mix synthetic preservatives into these treated substances or use pasteurization at temperatures of from 70 to 85° C. The intention is also to achieve a reduction in the quantity of the agents employed for the improvement in durability and the stabilization.
- According to the invention, this object is achieved by a process adjuvant which comprises at least one microbicidally active flavouring substance, preferably at least two flavouring substances.
- The invention furthermore relates to a process adjuvant which is characterized in that it comprises at least one microbicidally active flavouring substance, preferably at least two flavouring substances.
- Finally the present invention also relates to the use of the process adjuvant for impacting the surfaces of microbially perishable products and/or their environment for the purpose of spreading, lubricating, emulsifying, separating, cleansing, spraying, nebulizing, gasifying and cutting.
- The flavouring substances which are contained in the novel process adjuvants are exclusively natural or identical-to-nature flavouring substances which are recognized, under FEMA, as being safe (GRAS—generally recognized as safe). The aforementioned list is the FEMA GRAS Flavouring Substances List GRAS 3-16 Nos. 2001-3834 (as of 1993), which lists natural and identical-to-nature flavouring substances which are authorized by the American Public Health Authority FDA for use in foodstuffs (FDA Regulation 21 CFR 172.515 for identical-to-nature flavouring substances (Synthetic Flavouring Substances and Adjuvants) and FDA Regulation 21 CFR 182.20 for natural flavouring substances (Natural Flavouring Substances and Adjuvants). Flavouring substances which meet these FDA standards can be employed in a “quantum satis” manner, i.e. they may be present in the foodstuff up to the highest concentration at which they still do not impair the smell or taste of the foodstuff to which they have been added. The flavouring substances listed under FEMA coincide, to a large extent, with the substances contained in the corresponding European standard COE.
- According to the invention, the flavouring substances classified as “NAT4” according to Article V of European Community Directive Flavourings (22.06.88) may also be used provided that they are regarded as being safe in accordance with the abovementioned FEMA GRAS list. NAT4 substances are substances which can be declared to be identical-to-nature under certain conditions, for example when the substances are employed in combination with, and as a constituent of, a natural or identical-to-nature flavouring substance.
- The particular advantage of the novel process adjuvants is that, owing to their constituents being listed in the FEMA GRAS list and being recognized by the US Public Health Authority FDA, which is probably the most critical health authority of all, as being harmless, they can readily be added to foodstuffs in the “quantum satis” concentration range.
- A further particular advantage is that the process adjuvants do not affect the taste and smell of the treated products.
- The novel process adjuvants are employed, for example, in the form of lubricants, emulsifiers, washing agents, sprays, nebulizing agents, gas-phase-active agents, heat-transferring agents and also cutting agents or separating agents. The process adjuvants may also be employed as additives which are included in the said agents.
- It is important for the invention that the process adjuvants are not added to the foodstuffs or mixed with them. Rather, it is only the surfaces or cut surfaces of the foodstuffs which are impacted with the process adjuvants. This can take place by the foodstuff surfaces or cut surfaces being impacted directly with the process adjuvants. However, it is also possible to treat the surfaces of utensils, production machines, packaging equipment, transport equipment, packaging materials and the environmental air with the process adjuvant.
- It is surprising, according to the invention, that the microbicidal effect of the process adjuvants is seen even when low concentrations are used. Only from 0.01 to 5 g, preferably from 0.05 to 1 g per kg of foodstuff is used when the process adjuvants are impacted. In a preferred embodiment, 0.01 to 1.0 g/kg of process adjuvant per food stuff is used, more preferred 0.01 to 0.5 g/kg, and most preferably 0.05 to 0.5 g/kg. When they are used for the environmental air, only from 0.001 to 10 g are employed, for example, per M3 of air. Indeed, only from 0.000001 g to 0.1 g/cm2 of surface is used for the surfaces of utensils.
- When these concentrations are adhered to, the detectable quantities in the foodstuffs are only about 0.001% by weight. By contrast, from 0.1 to 3% by weight of preservative is regularly present in the foodstuffs in accordance with the state of the art. Despite these extremely low concentrations, it is surprising, according to the invention, that an extension of the durability of up to 50% can be achieved as compared with conventionally preserved foodstuffs.
- It is particularly to be emphasized, and astonishing, that even 0.001% by weight of a process adjuvant applied indirectly to foodstuffs, is sufficient to stabilize and/or improve durability while at the same time increasing product quality.
- This effect is all the more surprising in that the time over which the flavouring substances employed in accordance with the invention exert their microbicidal effect is less than 24 hours, preferably less than 12 hours. It is very particularly preferred to select process adjuvants and concentrations such that the time for the microbicidal effect is less than 1 hour, preferably less than 15 minutes.
- In contrast to this, the aim of the conventional preservatives is to be active in the foodstuff for as long as possible, i.e. over weeks and months. Despite the very short time during which the process adjuvants employed in accordance with the invention exert their effect, the durability is significantly increased as compared with that of foodstuffs which have been treated in accordance with the state of the art with conventional preservatives or preservation processes.
- The novel process adjuvant comprises flavouring substances which are selected from the group of the alcohols, aldehydes, phenols, acetates, acids, esters, terpenes, acetals, and their physiologically tolerated salts, ethereal oils and plant extracts.
- Preferred embodiments of the novel process adjuvants comprise one or more flavouring substances selected from one or more of the following groups:
- I. Alcohols
- Acetoin (acetylmethylcarbinol), ethyl alcohol (ethanol), propyl alcohol (1-propanol), isopropyl alcohol (2-propanol, isopropanol), propylene glycol, glycerol, benzyl alcohol, n-butyl alcohol (n-propylcarbinol), iso-butyl alcohol (2-methyl-1 propanol), hexyl alcohol (hexanol), L-menthol, octyl alcohol (n-octanol), phenyl ethyl alcohol (2-phenylethanol), cinnamyl alcohol (3-phenyl-2-propen-1-ol), a-methylbenzyl alcohol (1-phenylethanol), heptyl alcohol (heptanol), n-amyl alcohol (1-pentanol), iso-amyl alcohol (3-methyl-1-butanol), anise alcohol (4-methoxybenzyl alcohol, p-anise alcohol), citronellol, n-decyl alcohol (n-decanol), geraniol, b-hexenol (3-hexenol), hydrocinnamyl alcohol (3-phenyl-1-propanol), lauryl alcohol (dodecanol), linalool, nerolidol, nonadienol (2,6-nonadien-1-ol), nonyl alcohol (1-nonanol), rhodinol, terpineol, borneol, clineol (eucalyptol), anisole, cuminyl alcohol (cuminol), 1-phenyl-1-propanol, 10-undecen-1-ol and 1-hexadecanol.
- II. Aldehydes
- Acetylaldehyde, anisaldehyde, benzaldehyde, iso-butyl aldehyde (methyl-1-propanal), citral, citronellal, n-caproaldehyde (n-decanal), ethyl vanillin, fufurol, heliotropin (piperonal), heptyl aldehyde, (heptanal), hexyl-aldehyde (hexanal), 2-hexenal (β-propylacrolein), hydrocinnamaldehyde (3-phenyl-1-propanal), lauryl aldehyde (dodecanal), nonyl aldehyde (n-nonanal), octyl aldhehyde (n-octanal), phenylacetaldehyde (1-oxo-2-phenylethane), propionaldehyde (propanal), vanillin, cinnamaldehyde (3-phenylpropenal), perillaldehyde and cuminaldehyde.
- III. Phenols
- Thymol, methyleugenol, acetyleugenol, safrole, eugenol, isocugenol, anethole, phenol, methyl chavicol (estragole; 3-(4-methoxyphenyl)-1-propene), carvacrol, α-bisabolol, fornesol, anisole, (methoxybenzene) and propenylguaethol (5-propenyl-2-ethoxyphenol).
- IV. Acetates
- Isoamyl acetate (3-methyl-1-butyl acetate), benzyl acetate, benzylphenyl acetate, n-butyl acetate, cinnamyl acetate (3-phenylpropenyl acetate), citronellyl acetate, ethyl acetate, eugenol acetate, (acetyleugenol), geranyl acetate, hexyl acetate (hexanyl ethanoate), hydrocinnamyl acetate (3-phenylpropyl acetate), linalyl acetate, octyl acetate, phenylethyl acetate, terpinyl acetate, triacetin (glyceryl triacetate), potassium acetate, sodium acetate, and calcium acetate.
- V. Acids and/or Their Physiologically Tolerated Salts
- Acetic acid, aconitic acid, adipic acid, formic acid, malic acid (1-hydroxysuccinic acid), caproic acid, hydrocinnamic acid, (3-phenyl-1-propionic acid), pelargonic acid (nonanoic acid), lactic acid (2-hydroxypropionic acid), phenoxyacetic acid (glycolic acid phenyl ether), phenylacetic acid (a-toluic acid), valeric acid (pentanoic acid), isovaleric acid (3-methylbutanoic acid), cinnamic acid (3-phenylpropenoic acid), citric acid, mandelic acid (hydroxyphenylacetic acid), tartaric acid (2,3-dihydroxybutanoic diacid; 2,3-dihydroxysuccinic acid), fumaric acid, and tannic acid.
- VI. Esters
- Allicin.
- VII. Terpenes
- Camphor, limonene and)i-caryophyRene.
- VIII. Acetals
- Acetal, acetaldehyde dibutyl acetal, acetaldehyde dipropyl acetal, acetaldehyde phenethylpropl acetal, cinnamaldehyde ethylene glycol acetal, decanal dimethyl acetal, heptanal dimethyl acetal, heptanal glyceryl acetal and benzaldehyde propylene glycol acetal.
- IX. Polyphenol
- X. Ethereal Oils and/or Alcoholic or Glycolic Extracts, or Extracts which are Obtained by CO2 High-Pressure Processes, from the Plants Listed Below:
- a) Oils or extracts containing a high proportion of alcohols: balm, coriander, cardamom, eucalyptus;
- b) Oils or extracts containing a high proportion of aldehydes: Eucalyptus citriodora, cinnamon, lemon, lemongrass, balm, citronella, lime and orange;
- c) Oils or extracts containing a high proportion of phenols: oreganum, thyme, rosemary, orange, carnation, fennel, camphor, tangerine, anise, cascarilla, tarragon and allspice;
- d) Oils or extracts containing a high proportion of acetates: lavender;
- e) Oils or extracts containing a high proportion of esters: mustard, onion and garlic;
- f) Oils or extracts containing a high proportion of terpenes: pepper, Seville orange, caraway, dill, lemon, peppermint and nutmeg.
- Isopropanol and ethanol are not used if the process adjuvant comprises only one of the said flavouring substances. Surprisingly, it has been found that a combination of at least two of the given flavouring substances has a far greater effect than that produced by one single substance.
- Most of the flavouring substances listed in the GRAS FEMA list are not water-soluble, i.e. they are hydrophobic. If they are employed in foodstuffs which primarily contain fat, they can be used directly without solvents owing to their lypophilic character. However, the proportion of lypophilic foodstuffs is relatively small. In order to ensure that they can exert their effect in foodstuffs, animal feeds, cosmetics or pharmaceuticals which are in the main hydrophilic, they are preferably employed in combination with a water-soluble solubilizer. In order to do justice to the claim of this invention—to make available process adjuvants which are harmless from the point of health—use is made exclusively of solubilizer-flavouring substances, e.g. alcohols, which are authorized for food stuffs.
- The process adjuvants are used undiluted and/or in water-soluble dilutions with water and/or solvents (e.g. alcohols) which are authorized for food stuffs and/or in fat-soluble dilutions with vegetable (fatty) oils.
- In the novel process adjuvants, use can be made, for example, of readily water-soluble alcohols, preferably in concentrations of from 0.1 to 99% by weight, based on the process adjuvant, in combination with other flavouring substances. In a preferred embodiment, the process adjuvant comprises a GRAS flavoring compound that is an alcohol, and an additional different GRAS flavoring compound. Preferably, the additional GRAS flavoring compound is at least 0.001% by weight of the processing adjuvant, more preferably at least 0.01% by weight, and most preferably at least 0.05% by weight. The novel process adjuvants preferably comprise less than 50% by weight of ethanol, isopropanol or benzyl alcohol, or of a mixture of these compounds. It is particularly preferred if the proportion of the said alcohols is less than 30% by weight, in particular less than 20% by weight. Provided process adjuvants are employed which comprise benzyl alcohol and at least one further flavouring substance, the proportion of benzyl alcohol can also be more than 50% by weight. Surprisingly, the process adjuvants which comprise, for example, only 20% by weight of ethanol or isopropanol in combination with flavour aldehydes and flavour phenols in concentrations which are in the per 1000 range possess a very powerful fungicidal and bactericidal effect; even process adjuvants which comprise 1% by weight of the said water-soluble alcohols in combination with less than 3% of flavour aldehyde and flavour phenol exhibit a 70 to 100% microbicidal effect.
- From the above, it follows that the novel process adjuvants possess surprising microbicidal effects in the production environment or in the production process environment.
- In this context, preference is given to using the process adjuvants for producing foodstuffs, animal feeds, cosmetics, pharmaceuticals, paints, paper and/or cellulose.
- In particularly preferred embodiments, the process adjuvants are used for improving the durability of, and stabilizing, foodstuffs selected from the following group:
- bread, baked goods, baking agents, baking powders, blancmange powders, beverages, dietetic foodstuffs, essences, delicatessen foodstuffs, fish and fish products, potatoes and products based on potatoes, spices, flour, margarine, fruit and vegetables and products based on fruit and vegetables, pickled foodstuffs, starch products, confectionery, soups, pastas, meat and meat products, milk, dairy and cheese products, poultry and poultry products, oils, fat and oil-containing or fat-containing products.
- The novel process adjuvant exerts its effect in the environment of the product, for example a foodstuff or animal feed, which is susceptible to spoilage, e.g. on machine parts which are in contact with the product to be worked or processed, or in the air. As a result of direct contact with the surface of the product susceptible to spoilage, they also exert their effect there, i.e. they display their effect on the surface or, when penetrating into the product, in the latter itself.
- The particular advantage of the novel process adjuvant is, therefore, that on the one hand it decontaminates in a dependable manner, with its activity against Gram-positive and Gram-negative bacteria, fungi, including yeast, and viruses having been proved, while, on the other hand, it does not constitute any danger for the consumer of the foodstuff since it is completely harmless to this consumer and does not possess any microbicidal, technological after effect in the foodstuff, since the microbicidal activity relates to the production environment, which is freed from contaminating microorganisms by the novel measures.
- The novel process adjuvant can be a lubricant which is used simultaneously for lubrication, for decontamination of the lubricated parts and consequently, indirectly, for stabilizing the durability of the products which are in contact with these parts.
- According to the invention, the process adjuvant can also be an emulsifier, a separating agent or a cleansing agent. Such agents are used for emulsification and/or cleansing and consequently also for decontaminating surfaces, articles, machines, equipment, utensils, cutting surfaces and cutting devices, transport devices and the like. The adjuvant can furthermore be used for decontaminating and cleansing foodstuffs, raw materials, cosmetics, pharmaceuticals, paints, paper, cellulose, livestock, poultry, fish and garbage.
- In addition to this, the novel process adjuvant can be a spray. Such a spray enables the decontaminating active compounds to be finely distributed on all machine parts, transport devices, cutting devices, working surfaces, etc., and can simultaneously result in foodstuffs which are packed immediately after the cutting or separating procedure and/or packaging/portioning procedure being stored in a climate which possesses decontaminating and/or durability-stabilizing properties as the result of enclosed spray. In addition to this, nebulizable or sprayable embodiments are very economical owing to the comparatively small amounts required.
- The spray can also be blown or sprayed/nebulized into and/or onto packaging, for example packets, cartons or the like, in order thereby to preserve the product which is packed therein for a longer period.
- The sprays can also be nebulized in the production environment (surroundings, refrigeration, ventilation, fresh air) at hygienic weak spots (e.g. cooling sections), in order thereby to reduce the number of organisms without the personnel operating in this environment being harmed.
- The process adjuvants may also be employed for spraying onto foodstuff surfaces or cut surfaces in order to eliminate or reduce the spoilage causing agents which are present on the foodstuffs.
- Furthermore, these sprays can be employed in transport equipment, stores and coldrooms, and the like.
- The process adjuvant may also be employed by dipping the foodstuff, packaging materials, all machine parts, transport devices, cutting devices, working surfaces, etc., into the process adjuvant.
- In a further embodiment, the novel process adjuvant is a gas-phase active agent which is used for active decontamination and/or deodorizing in the gas phase in systems, such as packages, waste systems, container systems, transport spaces, storage spaces and the like, which are more or less closed. The packed goods, which are contained, transported or stored in the container, as well as the air and the particular environment, profit from the effect of the gas-phase agent.
- The novel process adjuvant has also proved to be a good heat transferring agent. By heat-transferring agents are meant cooling agents, heating agents and warming agents which can be used as decontaminating additives in circulating circulatory systems of liquid cooling systems, heating systems and warming systems. In this context, they are added to aqueous or oily systems to prevent the growth of microorganisms in the liquids in order, for example, to prevent contamination occurring in association with the leakage of refrigeration systems.
- In a particularly preferred embodiment, the novel process adjuvant is a cutting agent or separating agent for cutting knives and/or cutting devices of every kind and for all perishable products which are to be cut, in order to prevent contamination of the cutting sites.
- In the foodstuffs industry, contaminations with Gram-negative or Gram-positive pathogens, moulds, yeasts and other possible spoilage-causing agents often occur at the cutting sites or separation sites of foodstuffs, which contaminations can impair, sometimes substantially, the durability of the cut or separated products and consequently cause both economic damage and damage to health. The contaminations are introduced by raw materials, product/raw material residues and personnel and also by machine parts or operationally associated processes or by the air.
- Conventionally, therefore, the cut or separated foodstuffs, or the foodstuffs which are to be cut or separated, are still either pasteurized or treated technically in order to decontaminate them, and thereby preserve them, or are treated with preservatives. However, as already mentioned above, a thermal treatment is not possible or admissible in every case and can lead to a diminution in the quality of the product in some circumstances.
- A flanking measure for improving the durability of foodstuffs is the purification or even disinfection of the environment using chemical disinfectants which are subject to the biocide regulation. These substances are more or less poisonous and should not be transferred to foodstuffs. However, chemical disinfection is a discontinuous measure which can, in practice, only be applied to machine parts and to the environment at particular times during production and after whose implementation it is subsequently necessary. to flush with water in order to remove the residual substances. Correspondingly, the direct and permanent elimination of spoilage-causing agents is not ensured.
- For this reason, attempts have been made in the state of the art to optimize machine hygiene by improving cleaning ability or by means of installations for generating or maintaining pure or organism-deficient or organism-free air. However, experience has shown that this has either not brought about an increased durability of cut or separated foodstuffs or is economically no longer justifiable or cannot be put into practice in a reliable manner.
- An example from the sliced bread industry demonstrates that the durability of sliced bread is substantially reduced, in comparison with whole bread, by the cutting or separating of bread varieties such as whole dough bread, wholemeal bread, white bread, mixed bread or toast bread and then packing it. Depending on the bread variety, the durability is between 2 and 5 days. As a result of the subsequent thermal treatment (pasteurization in ovens or microwave appliances at a core temperature of from 60 to 90° C.) which is usually carried out nowadays, the durability of bread is normally extended to from 4 to approx. 20 days when using normal vapour-permeable polyethylene bag wrappings. Owing to their lower vapour permeability, other films, for example made of polypropylene, which, however, are substantially more expensive, can achieve a longer durability. Synthetic polyester wrappings enclosing an introduced nitrogen-containing atmosphere result in even longer durability. However, all these measures are either very costly or can only be employed for expensive special products and special markets and sometimes lead to substantial losses in the quality of the sliced bread, for example as the result of condensate formation in the bread bag, as the result of a bread consistency which is too soft, or as the result of premature drying out. None of these measures solves the real causes of the contamination by the cutting or separating process, which process, by means of the cutting device, for example the cutting blades, introduces both the possible spoilage-causing agents which are present in the environment, and those which are present in a product or on the machine, into the foodstuff and distribute them therein.
- Either mineral compositions, which are no longer permitted in many countries, or vegetable cutting oils, which are often already contaminated themselves, i.e. polluted with bacteria, are customarily employed as cutting agents or separating agents. See, for example, G. Schuster: Investigations on mould contamination of sliced bread, Bäcker & Konditor [Baker and Confectioner] 27(11), pp. 345-347; G. Spicher: Die Quellen der direkten Kontamination des Brotes mit Schimmelpilzen; Das Schneidol als Faktor der Schimmelkontamination; [The sources of direct contamination of bread with moulds; cutting oil as a factor in mould contamination]; Getreide, Mehl und Brot [Cereals, flour and bread] 32(4), pp. 91-94.
- There is, therefore, a pressing need, which is satisified by the novel cutting agent or separating agent, for a cutting agent or separating agent which enables the machine parts which are in contact with the foodstuff to be decontaminated during the cutting process and thereby achieves an improved durability of the cut material.
- The novel cutting agent or separating agent can be employed wherever cutting or separating is taking place on an industrial scale and the material which is being cut can be subject to spoilage by bacteria or fungi or contamination with viruses. While this applies to celluloses and paper, for example, it also applies, in particular to foodstuffs and animal feeds.
- In a preferred embodiment, the novel process adjuvant is suitable for cutting or separating bread, baked goods, fish and fish products, potatoes and products based on potatoes, fruit and vegetable and products based on fruit and vegetable, confectionary, starch products, pastas, meat and meat products, cheese products, poultry and poultry products.
- If the novel process adjuvant is a cutting agent or separating agent (for example for cutting bread), this agent can then be prepared on a customary vegetable oil/fat/wax basis while adding microbicidal process adjuvants which are based on flavouring substances. The cutting agent or separating agent (for example for use in the meat products industry) can preferably, according to the invention, consist exclusively of one or more flavouring substances.
- Natural emulsifiers, for example lecithins at a concentration of from 1 to 25% by weight, can be added to the vegetable oils, vegetable waxes and vegetable fats, in correspondence with the state of the art. Examples of emulsifiers are lecithins, citric acid monoglycerides, diacetyl tartaric acid, N-acetylphosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidic acids and phosphatidylcholine. However, if the novel cutting agent or separating agent is prepared as a water-based emulsion, vegetable oils, vegetable fats and vegetable waxes having unsaturated and saturated C16-C18 fatty acids, which also have a viscosity of from about 10 mPas (20° C.) to about 500 mPas (20° C.), are then used.
- After having been mixed with water in a ratio of from 1:1 to 1:40, the cutting/separating agent, which has been assembled, for example, from the abovementioned fatty acids or oils and emulsifiers, can then be used as a cutting emulsion or separating emulsion (milk).
- In practice, the novel cutting agent or separating agent is applied at least to the machine parts which are in contact with the material which is being cut in order to decontaminate these parts. Based on experience, the agents are employed in doses of 1-20 g/kg of foodstuff with the dose depending on the cutting or separating device used and the material being cut.
- The cutting/separating agents are usually applied to the cutting or separating devices, for example sprayed onto circular dish wheel cutting machines when slicing bread, which are then used to cut sliced bread, for example. According to the invention, parts of the cutting devices, for example circular dish knives, band slicers (rotating band-saws), electrical or mechanical knives or knife devices, electrical or mechanical saws or sawing devices, and electrical or mechanical chain saws or devices, are wetted in this context such that the cutting or separating agent can exert a decontaminating or microbicidal effect on the corresponding machine part and also on the surface which results from the cutting or separating.
- The advantageous effect of the novel cutting/ separating agents is expressed in an extended durability of the material which is being cut, for example sliced bread. It is based, not least, on the fact that the cutting and separating agent penetrates the surface of the material which is being cut and also decontaminates tile deeper layers of the cut foodstuff, specifically using the flavouring substances contained in the cutting oil.
- In addition to this, the flavouring substances described here also exert a microbicidal effect in the vapour phase, since most flavouring substances volatilize readily. They therefore exert their effect in the so-called environment of the foodstuff, for example in packaging the foodstuff, when the latter is packed, for example, in a film wrapping after the cutting process.
- This process of decontaminating the cut material after the actual cutting procedure can be supported by a mild thermal aftertreatment of the foodstuff without the latter losing any quality in its packaging. Thus, after having been sliced, bread, for example, is packed in polyethylene films and then brought, for example by means of microwave treatment, within from 10 seconds to 5 minutes, to a core temperature of between 300 and 50° C., or treated thermally for up to 1 hour at a core temperature of from 30° to 50° C., which reinforces the decontaminating effect of the cutting at separating agent.
- The advantageous effect of the cutting/separating agents can in some cases be substantially increased if the application and cutting or separating techniques are improved, or freshly developed, such that the foodstuff is intensely wetted with cutting or separating agent. For example, in experiments on bread slicing, the circular dish cutting blade was provided with separate slot guides and grooves, thereby rendering possible a more thorough and intense application of cutting or separating agent.
- The following examples explain the invention.
- It is already known in the state of the art that ethanol and isopropanol are microbicidal in high concentrations (75% by weight to more than 90% by weight). However, additives containing such a high concentration of ethanol or isopropanol are more likely to be undesirable owing, on the one hand, to the dangers in handling them, in particular their ready flammability, and, on the other hand, from considerations of principle, for example with regard to children or former alcoholics. However, if the ethanol or isopropanol concentration is reduced to 20% by weight, or less, based on the process adjuvant, there is no longer any detectable bactericidal or fungicidal effect, as is demonstrated in the table below.
TABLE Microbicidal and/or fungicidal effect of ethanol and isopropanol1 Staph. aureus Asp. niger Duration of action, 1 h Duration of action, 1 h Isopropanol, 20% by wt. RF2 0.3 RF. 0.5 Ethanol, 20% by wt. RF 3.4 RF 0 Growth control log CFU3: 7.5 log CFU: 5.4 Isopropanol, 75% by wt. RF 7.0 RF 5.4 Ethanol; 75% by wt. RF 7.0 RF 5.4 Growth control log CFU: 7.0 log CFU: 5.4
1The results were obtained by means of a quantitative suspension experiment (see “Materials and methods”, Chapter 3.2).
2RF (reduction factor): log of original number of organisms minus log of number of surviving organisms.
3CFU: colony-forming units
- The efficacy of process adjuvants was tested in a variety of experiments. These experiments demonstrate that these adjuvants improve durability and stability in a surprising manner when they are employed as cutting agents, as sprays, as cleansing agents or as separating agents. In this way, it was possible greatly to reduce the number of spoilage-causing organisms on cutting surfaces, transport surfaces or slicing surfaces. At the same time, the durability of sausage, for example, was extended by 30% as compared with a conventional preservation.
- Taking the example of bread, durability is significantly improved by spraying bread loaves, and slices of the bread, with cutting agent, by means of spraying the process adjuvant onto the surfaces of the cutting knives.
- Taking the example of baked goods, it was possible to demonstrate that the content of moulds per m2 of air was significantly reduced when a process adjuvant was nebulized. The durability was substantially improved without any further addition of preservatives to the bread or the baked goods.
- Use of a process adjuvant as a cutting agent for cutting knives and as a spray for conveyor belts and bands in butchery.
- Method Description:
- a)-c) investigates the organism number of acid-formers such as lactobacilli. The customary laboratory technique, a dilution series and casting agar, was applied to determine this organism number.
- Nutrient medium used: MRS agar (OXOID)
- d) The spreading method was used to determine the organism-reducing effect on the surface of sausage.
- The number of organisms was determined beforehand, after an exposure time of 10 minutes (after spraying with HIQProSlice, registered trade mark of Schür in Process GmbH), after cooling and prior to packaging.
- Nutrient medium for the total number of organisms: RODAC containing TSA, TW 80 and lecithin.
-
- Surface: 25 cm2
Sample Description:
Grilling sausage was selected as the subject for the investigation.
The product has a durability of 2-3 weeks.
Grilling sausage is produced as follows:
- Surface: 25 cm2
- Lean and fat are cut in the cutter and mixed with ingredients. After the intestine has been filled, the sausage is heated in water at 75° C. After cooling, the products are vacuum-packed with 3 sausages being included in each pack.
Sample no.: Sample description 1 Grilling sausage, zero sample 2 Zero sample + ProSlice on outer skin (1 g/1000 g of sausage) 3 Equipment decontaminated with ProSlice 4 As 3 + ProSlice on outer skin (1 g/1000 g of sausage 5 As 3 + 1% ProSlice as additive 6 As 5 + ProSlice on outer skin (1 g/1000 g of sausage) 7 As 3 + 3% ProSlice as additive 8 As 7 + ProSlice on outer skin (1 g/1000 g of sausage)
Results: - a) The durability of a product, when used as additive.
Number of lactobacilli organisms/g Sample No. Day 1 Day 7 Day 14 1 100 31,000 2,100,000 5 200 26,000 5,000,000 7 100 40,000 5,000,000 - b) The durability of a product, when used as spray on the outer skin of the product
Number of lactobacilli organisms/g Sample No. Day 1 Day 7 Day 14 1 100 31,000 2,100,000 4 <100 2,700 450,000 6 <100 19,000 1,100,000 8 <100 18,000 1,200,000 - c) The durability of a product, when used as spray on surfaces directly in contact with the product.
Sample No. Day 1 Day 7 Day 14 1 100 31,000 2,100,000 3 200 5,500 900,000 - d) The organism number after spraying on the outer side of the product. Beforehand (Sample 1)
Total number of Total number of organisms/ organisms/25 cm2 25 cm2 after 10 minutes Sample No. beforehand exposure time 1 120 95 2 65 No growth 4 110 No growth 6 Lawn growth No growth 8 18 No growth
Comments on:
a) The durability of a product, when used as additive. - The Table demonstrates that the addition of HIQProSlice, even in substantial quantities, has no effect on the extension of durability. The HIQProSlice has no preserving effect when added as an additive.
- b) The durability of a product, when used as a spray on the outside of the product.
- The table demonstrates that an improvement in durability is obtained by spraying the sausage with 1 g per 1000 g of product.
- c) The durability of a product, when used as a spray on surfaces directly in contact with the product.
- The Table demonstrates that an improvement in durability is obtained by spraying the surfaces and utensils.
- d) The number of organisms after spraying the outside of the product.
- A reduction in the number of microorganisms of an RF log of at least two is obtained within 10 minutes by spraying the sausage surface.
- Technological (after)effect of process adjuvants for spraying using the example of a spray/cutting agent for cutting and spraying the transport devices during the production/cutting up of poultry meat.
- Result of testing HIQ Pro Chick (1%) for the abolition of a bactericidal/bacteriostatic effect (syn. microbiological/technological after effect) after contact with poultry protein following method B 4.2.3. BGA according to E. Petermann and G. Cerny.
- Material under investigation: 1 sample of EEIQ Pro Chick concentrate, registered trade mark of Schür in Process GmbH, Möchen-gladbach
- Investigation method: B IV 4.2.3. BGA, microbiological measurement method; Agar diffusion test
- Implementation: A 1% dilution in a lysate of a chicken breast fillet, from Wiesenhof, HKL-A having a protein content of 30 g/l (Biuret method) was first of all prepared from the submitted material. This mixture was incubated at 6° C. for 18 h. On the following day, 10 ml, 50 ml and 100 ml of this mixture were pipetted into a CASO agar which was at pH 7.0 and into which spores of Bacillus subtilis BGA strain (DSM 614) had been poured; 3 wells per mixture.
- After a 2 hour prediffusion at 4° C., the plates containing the Bacillus spores were incubated at 30° C. for 3 days and then checked for inhibition haloes.
- A small antibiotic plate served as positive control for the Bacillus strain, while an agar sample which was only treated with spores was used as the growth control.
- In addition, the HIQ Pro Chick was examined, both in the above quantities and as a concentrated, 10% and 1% solution, without protein contact, for an inhibitory effect against Bacillus subtilis. This batch was implemented on 2 different days.
- Investigation result: Positive control: inhibitory halo of 40 mm around the antibiotic Growth control: good growth of Bacillus subtilis BGA Sample under investigation: 1% of HIQ Pro Chick in protein: No inhibitory haloes with 10, 50 and 100 ml sample quantities.
- HIQ Pro Chick without protein: No inhibitory haloes with 10, 50 and 100 ml sample volumes and 100%, 10% and 1% solution.
- Assessment in accordance with Method B IV 4.2.3. BGA:
- According to the BGA (BgVV) test method employed in this case, it is not possible to demonstrate that the HIQ Pro Chick sample has any bactericidal or bacteriostatic effect, i.e. any microbiological/technological aftereffect with chicken muscle extract either, in any of the experimental mixtures, even at a 10-fold dosage.
- Process adjuvant for spraying cutting knives, as a cutting agent, and for spraying transport devices, using the example of sliced sausage and considering the reduction of spoilage-causing agents (enterobactetia/lactobacilli) on cutting knives, transport devices and cut sausage surfaces, and improvement/extension of durability.
- 2a. Standard Method
Found Sample Sample Total number No.: description of organisms/7 cm2 Comments 1 Belt 67 2 Belt ±100 3 Belt ±100 4 Belt 51 20 moulds 5 Sausage supporter 8 6 Sausage supporter 0 7 Knife (outer side) 39 8 Knife (inner side) 28 9 Knife box Huge numbers (inner side) - 2b. After having Treated Cutting Surfaces and Transport Surfaces
Sample Sample Found No.: description Total number of organisms/7 cm2 18 Belt after smearing with 1 paper (13:12 h) 19 Belt after smearing with 0 paper (13:12 h) 20 Belt after smearing with 0 paper (13:22 h) 21 Belt after smearing with 1 paper (13:20 h) 22 Belt after smearing with 18 paper (13:30 h) 23 Belt after smearing with 4 paper (13:30 h) 24 Belt during continuous 0 spraying 25 Belt during continuous 0 spraying 26 Sliced sausage (above) 1 27 Sliced sausage (below) 0
2c. Checking the Durability of Packed Sausage
Sample designation:
V=Sample prior to treatment
M=Sample after smearing
R=Sample after only spraying the belt - MB=Sample during continuous spraying of the belt and the knife
Total no. Spore Date Sample of orgs. Entero Lacto Staph. Yeast Moulds formation Week 1 V <102 <10 <102 <102 <102 <102 <102 M <102 <10 <102 <102 <102 <102 <102 R <102 <10 <102 <102 <102 <102 <102 MB <102 <10 <102 <102 <102 <102 <102 Week 2 V 7.2 * 103 <10 >3 * 106 <10 <10 <10 <102 M 3.2 * 102 <10 2 * 102 <10 <10 <10 <102 R 1.4 * 103 <10 1.5 * −103 <10 <10 <10 <102 MB 1.8 * 104 <10 1.7 * −104 <10 <10 <10 <102 Week 3 V 4.2 * 105 20 2.9 * −108 <102 <102 <102 <102 M 2.4 * 104 60 6.3 * −104 <102 <102 <102 <102 R 6.3 * 105 1.2 * 104 3.0 * −105 <102 <102 <102 <102 MB 4.0 * 105 90 6.0 * 105 <102 <102 <102 <102 Week 4 V 7.0 * 107 <10 2.9 * 108 <102 <102 <102 <102 M 8.0 * 107 <10 6.3 * 104 <102 200 <102 <102 R 1.8 * 107 <10 3.0 * 105 <102 <102 <102 <102 MB 104 <10 6.0 * 105 <102 <102 <102 <102 Week 5 V 3.5 * 108 <10 6.6 * −108 <102 <102 <102 10 M 5.0 * 105 <10 7.0 * −106 <102 200 <102 250 R 104 <10 105 <102 <102 <102 50 MB 2 * 102 <10 <102 <102 <102 <102 30
Results: - When sliced sausage is being produced, its durability increases indirectly due to the continuous use of the process adjuvants on the cutting knives and the transport device since the number of spoilage-causing agents appearing on the devices is substantially reduced.
- According to the abovementioned experimental results, the durability of sausage is significantly improved by using the cutting agent which is applied to the cutting devices. At the same time, there is surprisingly good cleaning of the cutting surfaces of the cutting devices. Furthermore, the cuttability of the sausage is improved. The durability is substantially improved despite the high dilution of the substances employed. Outstanding results can be obtained with vegetable oils in dilutions of from 1:10 to 1:100.
- Process adjuvant for cutting (cutting oil), by means of spraying on cutting knives (band slicer) and circular dish cutting machine, and spray for spraying the surfaces of the foodstuff, using toast bread as an example and considering the reduction of spoilage-causing agents on the machine parts and bread surfaces and/or cutting surfaces (moulds/Aspergillus niger) while at the same time improving/extending durability.
- Legend: Mould colour: G=Green, Y=Yellow, BL=Black, W=White and C=Chalk
- Site at which mould found
- A=Above, B=Below, S=Side, CS=Cutting surface and V=Various sites
- 3b. Environment Hygiene
Sample No.: Description Time Bact./m3 Moulds 1 Entry 15:15 h 260 50 band slicer 2 Exit slicer 15:25 h 225 25 3 Cooling tower, 15:30 h 13 <13 middle of room 4 Packaging 15:30 h 400 62 machine 5 CO2 injector 15:40 h 750 88 6 Packaging 16:00 h 63 25
Result: - When sliced bread is being produced, its durability is extended indirectly by the continuous use of the process adjuvants for spraying onto bread surfaces and cutting the bread with cutting oil (addition of the process adjuvant, in proportion to the cutting oil, to the cutting oil), since the number of moulds spoilage-causing agents) is substantially reduced. Chemical preservation or pasteurization is no longer necessary.
- Process adjuvant for nebulizing in the air, considering the reduction of the spoilage-causing agents in the air (mould/Aspergillus niger) and prevention of resedimentation onto baked goods, using baked goods as an example, with the result that durability is improved/extended.
- 4a. Measurement of the Number of Organisms in the Air Prior to the Treatment
- Biotest Air sampler, in each case 2 min. (80 ltr. of air)
Sample Sample No.: description Bacteria Moulds 1 Cold room before 38 nebulizing between the cooling towers 2 Stairs region before 1,500 entering the cold room 3 Exit from cold room to 2,500 625 packaging 4 1st cooling tower 75 13 before the cooling plant airstream, prior to nebulizing, 10:00 h 5 1st cooling tower 80 140 before the cooling plant airstream, directly prior to nebulizing, 11:30 h - 4b. Measurement of the Number of Organisms in the Air During/After the Treatment
Sample Sample No.: description Bacteria Moulds 6 1st cooling tower 15 13 before the cooling plant airstream, during nebulizing, 11:45 h 7 1st cooling tower 0 0 before the cooling plant airstream, at the end of nebulizing, 13:00 h 8 1st cooling tower 0 0 before the cooling plant airstream, after nebulizing, 14:00 h
4c. Durability Assessment after using Nebulizing Agent (Termed FOG)
Legend: Mould colour: G=Green, Y=Yellow, BL=Black, W=White and C=Chalk
Site at which mould found - A=Above, B=Below, S=Side, CS=Cutting surface, V=Various sites
- Additive=Preservative
- Fog=Without preservative and using the nebulizing agent in the air
- Result:
- When baked goods are being produced, their durability is extended indirectly by the nuous use of the process adjuvant for nebulizing in the air (cooling tower, cooling/transport section), with number of moulds in the air being substantially reduced. Chemical preservation or pasteurization of the d goods is no longer necessary.
- In the next examples, the following materials and methods were employed:
- Materials and Methods
1. Test E. coli ATCC11229 organisms: Staph. aureus ATCC6538 Ps. aeruginosa ATCC15442 C. albicans ATCC10231 A. niger ATCC16404 Cladosporium herbarum (our own isolate) 2. Nutrient CSA (Tryptone Soya Agar Oxoid CM media: 131) CSB (Tryptone Soya Broth Oxoid CM 129) YGC agar (Merck 16000) Tween 80 (Merck)
3. Implementation of the Tests
3.1. In-Vivo Test for Determining the Shortest Durability - The fungi and bacteria are taken up with a swab (stroke across the grown plate with turning movements) and spread uniformly, e.g. over the cut surface of a sliced bread sample so that a concentration of 103-104 spores or microorganisms is achieved per 100 cm2.
- 0.2-0.3 ml of the test substance is sprayed, using an aerosol spray, onto 100 cm2 of sliced bread surface. The test bread samples are packed in plastic bags (polyethylene or polypropylene) and the plastic bags are closed and stored at room temperature in the light.
- The growth of microorganisms on the contaminated bread samples is compared with that on control bread. The number of days after which a growth of microorganisms can be recognized with the naked eye for the first time is taken as the shortest durability.
- 3.2. In-Vitro Test: Quantitative Suspension Method in Accordance with DGHM I 2.3.1.1
- Overnight cultures (or, in the case of, for example, A. niger and C. albicans, 3-day cultures) are suspended in physiological saline (0.8%) until the desired concentration (106 fungal organisms/ml or 108 bacterial organisms/ml) has been reached. After that, 9 ml of the test substance are inoculated with 1 ml of the suspension.
- An exposure time of from 5 min to 1 hour is chosen for organisms such as Staph. aureus, Pseudomonas and E. coli, while an exposure time of 1.6 and 24 hours is chosen for A. niger and C. albicans. During the exposure time, the suspensions are shaken regularly.
- After expiry of the exposure time, a dilution series of the test suspension is set up in CSB (oxoid) which contains substances which inactivate the flavouring substance(s) which has/have been tested in each case. For example, 0.1% by weight of histidine is added for inactivating aldehydes, 1% by weight of Tween 80® is added for inactivating phenols, 0.2% by weight of Tween® is added for inactivating alcohols, and 0.03% by weight of lecithin is added for inactivating acids, esters, inter alia. In the case of bacteria, CSA (oxoid), in the case of A. niger/C. albicans YGC Agar (Merck), is poured over 1 ml of each dilution.
- After 24-48 hours of incubation, the plates are evaluated and the destruction factor is determined as the reduction factor (RF) in relation to a growth control of 105-107 CFU/ml.
- Deutsche Gesellschaft für Hygiene und Mikrobiologie [German Society for Hygiene and Microbiology]; Richtlinien für die Prüfung und Bewertung chemischer Desinfektionsverfahren [Guidelines for Testing and Evaluating Chemical Disinfection Methods]. Zentralblatt fur Bakteriologie, Mikrobiologic und Hygiene, Reihe B, Vol. 172, No. 6 (1981).
- 3.3 Gas-Phase Test Method
- The gas-phase test method is used to determine the destruction factor when using gas-phase-active process adjuvants.
- The determination is carried out in a so-called double petri dish. 0.5 ml of the gas-phase-active agent is added to, for example, bread or small urea/formaldehyde foam blocks (0.5′1′3 cm) which are located on an absorbing surface. The bread or the small foam blocks are placed in one compartment of a subdivided petri dish.
- A filter paper disc (diameter: 13 mm) which is inoculated with from approx. 108 to 109 organisms is placed in another compartment of the same petri dish. The dish is sealed in an airtight manner and incubated at a temperature of 30° C. for 24 hours.
- Following the incubation, the filter paper disc is suspended in 9 ml of CSB and a dilution series is prepared in CSB. The tubes are incubated at 30° C. and evaluated. The destruction factor is determined in comparison with the control.
- 3.4 Gas-Phase Suspension Method
- The gas-phase suspension method is used to carry out a first investigation for bactericidal and/or fungicidal properties.
- In order to carry out the method, melt molten nutrient media corresponding to the particular test microorganism concerned are inoculated with from 105 to 106 organisms per ml. The nutrient media are poured into petri dishes and cooled.
- 80 ml of the agent to be tested (additive or process adjuvant) are loaded onto a filter paper disc (diameter: 13 mm; Schleicher & Schüll, Article 601/2) and four of the filters prepared in this way are distributed uniformly on the surface of a prepared petri dish. The plates are subsequently incubated at 37° C. for 24 hours.
- After the incubation, the size of any region of inhibition which arises is determined.
- 3.5 Preservation Test
- The preservation test was determined in accordance with USP XXII/NF XVII, US Pharmacopeia, United States Pharmacopeial Convention, Rockville, Md. 20852.
- In this experiment, whose results are presented in the following Table, the individual effects of ethanol and isopropanol at concentrations of 20 and 1% by weight, and also the combined effect of 0.2% by weight of anisaldehyde and 0.04% by weight of oreganum oil, are compared with the synergistic effect of the combination of anisaldehyde, oreganum oil and in each case one of the aforementioned water-soluble alcohols. The experiment was carried out as a quantitative suspension experiment.
Reduction factors Exposure time, 1 h A. niger Staph. aureus Anisaldehyde, 0.2% by weight 0 3.3 Oreganum oil, 0.04% by weight (Active compound combination 5E) 20% by weight of ethanol 0 3.4 20% by weight of isopropanol 0.5 0.3 20% by weight of ethanol + 5E 5.4 7.7 20% by weight of isopropanol + 5E 5.4 7.7 1% by weight of ethanol 0 0 1% by weight of isopropanol 0 0 1% by weight of ethanol + 5E 0.9 7.7 1% by weight of isopropanol + 5E 0.1 5.5 Growth control log CFU: log CFU: 7.7 5.4 - The values indicate that a 1% solution of the alcohols used in this experiment, and also the active compound combination 5E on its own, are completely ineffective in the case of Aspergillus niger; the active compound combination 5E has a moderate effect in the case of Staphylococcus aureus. A 20% solution of alcohol on its own also has virtually no microbicidal effect on Aspergillus niger, whereas it is only the ethanol solution which has a moderate microbicidal effect on Staphylococcus aureus. However, a combination of ethanol or isopropanol with the active compound combination 5E almost always results, when a 20% solution of alcohol is used, in a 100% microbicidal effect; while a combination of 1% alcohol solutions with the active compound combination SE still gives a 70 to 100% microbicidal effect in the case of Staphylococcus aureus at least.
- The decontaminating and/or microbicidal activity of flavouring substances from the groups of the alcohols, aldehydes and phenols, and also different combinations from these groups, was once again determined using the quantitative suspension method.
- The results are presented in the following table.
TABLE Staph. aureus exposure time Asp. niger 1 h exposure time 1 h:6 h Reduction factor Individual % by weight Reduction factor1 (initial substances of flavouring (initial number of number of organisms Flavouring substance in organisms in log in log substances H2O CFU2/ml: 5.5) CFU/ml: 7.9) Group I: alcohol Anise alcohol 1% 0.3 1.0 2.1 Hydrocinnamyl alcohol 1% 0.3 3.2 7.9 Isopropanol 75% 5.5 5.5 7.9 Isopropanol 20% 0.5 1.5 0.3 Isopropanol 1% 0 0 0 Ethanol 75% 5.5 5.5 7.9 Ethanol 20% 0.5 0.3 Ethanol 1% 0 0 Group II: aldehydes Anisaldehyde 0.2% 0 4.2 Citronellal 0.2% 0 2.1 Perillaldehyde 0.2% 0 2.6 Group III: phenols Oreganum oil 0.04% 0 3.1 1.4 Rosemary extract 0.04 0.2 0.2 1.6 - The durability of sliced bread was investigated a) on bread which was sliced using conventional cutting agents and which was not inoculated with microorganisms, and on bread which was sliced using the novel cutting agent and which was artificially contaminated after having been sliced.
Durability of the sliced bread in days % by Control Cladosporium Staph. weight bread, herbarum A. niger aureus based on sliced 5 ′ 105 CFU/ 2 ′ 104 CFU/ 4 ′ 104 CFU/ the ready- bread, 100 cm2 100 cm2 100-cm2 Cutting/separating to-use untreated of of of agent agent 20° C. bread 20° C. bread 20° C. bread 20° C. a) Soya bean oil 99% 3 9 8 12 Anisaldehyde 1% b) soya bean oil 97.4% 3 7 6 10 Caprylcapric acid triglyceride lecithin 1% anisaldehyde 1% hydrocinnamyl 0.15% alcohol 0.45% - The results of this comparative experiment are given in the following Table.
Durability of sliced bread in days Cutting/separating Control agent Control bread sliced using bread sliced using according cutting oil without a novel cutting/separating agents to Table 6 process adjuvant according to Table 6 a 3 11 b 3 8 - The following table shows the durability of sliced bread which, on the one hand, was sliced using conventional cutting oil and, on the other, using cutting/separating agents according to Table 6, and which was not subjected to any thermal aftertreatment, and, subsequently, of such bread which was sliced using novel cutting/separating agents and subsequently subjected to a mild thermal after treatment.
TABLE 8 Durability of sliced bread in days Bread sliced using a cutting/ Control bread Control bread separating agent according to sliced using sliced using a Table 6 and subjected to a cutting oil cutting/separating thermal aftertreatment without a agent Exposure Core Durability Cutting/separating novel process according to time in temp. in agent adjuvant Table 6 s/min in ° C. days a 3 11 10 s 30° C. 12 30 s 36° C. 13 1 min. 41° C. 15 2 min. 45° C. 17 5 min. 50° C. 20 b 3 12 10 s 30° C. 13 30 s 36° C. 14 1 min. 41° C. 16 2 min. 45° C. 17 5 min. 50° C. 19 - The following process adjuvants are introduced below by way of example:
Example: 11 Cutting agent 12 Heat/cold transferring agent 13 Emulsifier, separating agent and cleansing agent 14 Lubricant 15 Gas-phase-active agent 16 Nebulizing agent 17 Spray - The recipe examples consist, by way of example, of individual and/or several flavour function groups combined amongst themselves and/or combined synergistically.
- The process adjuvants are used either undiluted or following dilution with water and/or foodstuff-admissible solvents and/or vegetable (fatty) oils and/or emulsifiers of from 0.01% by weight to 99.99% by weight, preferably in a mixing ratio of from 1:1 to 1:100.
- Some application examples for the use of one or more process adjuvants for durability stabilization and/or improvement and/or environment impaction in the case of, for example:
Process adjuvant Example employed No.: Toast bread Nebulizing agent 16 Cutting agent 11 Spray 17 Fancy cakes and pastries Nebulizing agent 16 Sliced sausage Cutting agent 11 Emulsifier, separating 13 agent, cleansing agent Grilling sausage Spray 17 Boiler water for heating chocolate Heat transferring agent, 12 mass cold transferring agent Conveyor belt Lubricant 14 Waste container Gas-phase-active agent 15 - The following recipe Examples 1-62 are representative examples of the flavour function groups individually or combined severally among each other and/or synergistically.
Example % Function group FDA flavour by weight 1 Alcohol Glycerol 100 2 Alcohol/ Glycerol/ 92 aldehyde hexyl aldehyde 8 3 Alcohol/ Acetoin/ 71 aldehyde/ anisaldehyde/anisole 20 phenol 9 4 Alcohol/ Propyl alcohol/thymol 95 phenol 5 5 Aldehyde- Acetaldehyde/ 84 phenol eugenol 16 6 Alcohol/ Citronellol/ 76 acid tartaric acid 24 7 Alcohol/ Anise 62 aldehyde/ alcohol/hydrocinnamaldehyde/ 28 acid citric acid 10 8 Alcohol/aldehyde/ Glycerol/ 40 phenol/ citral/ 14 acid estragole/ 18 tannic acid 28 9 Aldehyde Perillaldehyde 100 10 Aldehyde/ Perillaldehyde/formic 85 acid acid 15 11 Alcohol/ Benzyl 77 phenol/ alcohol/isoeugenol/ 18 acid fumaric acid 5 12 Acetate Linalyl acetate 100 13 Aldehyde/ Propionaldehyde/carvacrol/ 35 phenol/ phenyl acetic acid 20 acid 45 14 Acetal Acetal 100 15 Alcohol/ Cinnamyl alcohol/ 51 acetate hydrocinnamyl acetate 49 16 Alcohol/ Acetoin/ 55 aldehyde/ acetaldehyde/ 35 acetate eugenol acetate 10 17 Alcohol/ Isopropanol/citronellol 45 alcohol 55 18 Aldehyde/ Anisaldehyde/benzaldehyde 64 aldehyde 36 19 Acetate/ Sodium acetate/ethyl 50 acetate acetate 50 20 Acetal/ Cinnamaldehyde 63 acetal ethylene glycol 37 acetal/ acetaldehyde phenethylpropyl acetal 21 Phenol/ Thymol/ 25 phenol anisole 75 22 Acid/ Valeric acid/mandelic 30 acid acid 70 23 Ester/ Allicin/ 80 ester onion 20 24 Terpene/ Dill/ 24 terpene limonene 76 25 Phenol/ Thymol/ 35 polyphenol gallotannin 65 26 Phenol Carvacrol 100 27 Polyphenol Gallotannin 100 28 Acid Malic acid 100 29 Ester Allicin 100 30 Terpene Camphor 100 31 Alcohol/aldehyde/ Linalool/ 30 phenol/ heptanal/ 21 acetate propenylguaethol/ 18 triacetin 31 32 Alcohol/ Glycerol/ 40 aldehyde/ hydrocinnamaldehyde/ 18 phenol/ fornesol/ 13 acetate/ potassium acetate/ 19 acid phenylacetic acid 10 33 Acetate/ Sodium 44 aldehyde diacetate/acetaldehyde 56 34 Acetate/ Benzyl acetate/ 65 phenol a-bisabolol 35 35 Acetate/ Lavender/ 70 acid tartaric acid 30 36 Acetate/ Ethyl acetate/borneol/ 8 alcohol/ pelargonic acid 42 acid 50 37 Acetate/ Iso-amyl 30 aldehyde/ acetate/dodecanal/ 40 acid 3-methylbutanoic acid 30 38 Acetate/ Cinnamyl 35 phenol/ acetate/anethole/ 41 acid caproic acid 24 39 Acetate/ Calcium 50 alcohol/ acetate/heptanol/ 19 aldehyde/ benzaldehyde/ 10 acid acetic acid 21 40 Acetate/ Geranyl acetate/cineol/ 16 alcohol/ thymol/phenylacetic 35 phenol/ 20 acid 29 41 Acetal/ Heptanal glyceryl acetal/ 10 alcohol/ nerolidol/ 40 aldehyde propanal 50 42 Acetal/ Acetal/ 57 alcohol 1-phenylethanol 43 43 Acetal/ Acetaldehyde 70 acid phenethylpropyl acetal/ 30 nonanoic acid 44 Acetal/ Acetal/ 32 alcohol/ isopropanol/ 48 acid acetic acid 20 45 Acetal/ Acetal/ 88 phenol carvacrol 12 46 Ester/ Allicin/ 40 alcohol/ glycerol/ 40 terpene/ camphor/ 10 acid acetic acid 10 47 Ester/ Allicin/ 20 alcohol/ acetoin/ 60 aldehyde n-octanal 20 48 Ester/ Allicin/ 80 acid aconitic acid 20 49 Ester/ Allicin/ 88 phenol acetyl-eugenol 12 50 Ester/ Allicin/ 37 acetate sodium acetate 63 51 Ester/ Allicin/ 78 aldehyde acetaldehyde 22 52 Ester/ Allicin/ 8 alcohol/ rhodinol/ 62 acid tannic acid 30 53 Terpene/ Limonene/ 18 alcohol/ linalool 82 acid 54 Terpene/ b- 30 alcohol/ caryophyllene/coriander/ 35 aldehyde lemon grass 35 55 Terpene/ Camphor/ 15 ester/ allicin/balm/ 28 alcohol/ citric acid 7 acid 50 56 Terpene/ester/ Limonene/ 42 alcohol/ allicin/ 15 aldehyde benzyl alcohol/vanillin 25 18 57 Polyphenol/ Gallotannin/ 17 alcohol/ 2- 65 acid phenylethanol/pentanoic 18 acid 58 Terpene/ Limonene/ 70 acid fumaric acid 30 59 Terpene/ Camphor/ 20 phenol thymol 80 60 Terpene/ Limonene/ 63 acetate lavender 37 61 Terpene/ Limonene/ 48 aldehyde citral 52 62 Polyphenol/ Gallotannin/cuminol/ 29 alcohol/ cuminaldehyde 42 aldehyde 29 - The effective ness of aqueous systems containing ethanol; benzyl alcohol, ethanol+acid (e.g. lactic acid); or benzyl alcohol+acid (e.g. lactic acid); at a duration of action of 1.0 hours has been summarized in the following table:
Reduction Factors Bacteria Mold ethanol 1.0% by weight 0 0 benzyl alcohol 1.0% by weight 0 0 1.0% by weight ethanol + 0.2% 0 0 by weight lactic acid 1.0% by weight benzyl alcohol + 0.2% 3.6 1.5 by weight lactic acid growth control log CFU 7.7 log CFU 5.4 - At a lower concentration of <75%, ethanol and benzyl alcohol do not possess any microbiocidal capabilities. In contrast to ethanol (and similarly isopropanol), once having formed appropriate synergisms benzyl alcohol is capable of reducing bacterial growth and the growth of molds.
Claims (11)
1-17. (canceled)
18. A method for the improvement of the keeping quality and/or stabilization of microbially perishable products, wherein the surfaces of the products and/or their environment, especially the ambient air and/or the surfaces of the equipment or other materials immediately or intermediately contacting the products, are treated with one or more processing aids prior to, during or after the process for the manufacturing, processing or packaging of the products, wherein said processing aids are microbicidal compositions comprising at least two microbicidally active GRAS (generally recognized as safe) flavoring agents, said at least two GRAS flavoring agents being selected from the following group of combinations of GRAS flavoring agents:
(i) GRAS alcohol and GRAS aldehyde; (ii) GRAS alcohol, GRAS aldehyde and GRAS phenol; (iii) GRAS alcohol and GRAS phenol; (iv) GRAS aldehyde and GRAS phenol; (v) GRAS alcohol and GRAS acid; (vi) GRAS alcohol, GRAS aldehyde and GRAS acid; (vii) GRAS alcohol, GRAS aldehyde, GRAS phenol and GRAS acid; (viii) GRAS aldehyde and GRAS acid; (ix) GRAS alcohol, GRAS phenol and GRAS acid; (x) GRAS aldehyde, GRAS phenol and GRAS acid; (xi) GRAS alcohol and GRAS acetate; (xii) GRAS alcohol, GRAS aldehyde and GRAS acetate; (xiii) GRAS alcohol and GRAS alcohol; (xiv) GRAS aldehyde and GRAS aldehyde; (xv) GRAS acetate and GRAS acetate; (xvi) GRAS acetal and GRAS acetal; (xvii) GRAS phenol and GRAS phenol; (xviii) GRAS acid and GRAS acid; (xix) GRAS ester and GRAS ester; (xx) GRAS terpene and GRAS terpene; (xxi) GRAS phenol and GRAS polyphenol; (xxii) GRAS alcohol, GRAS aldehyde, GRAS phenol, GRAS acid and GRAS acetate; (xxiii) GRAS alcohol, GRAS aldehyde, GRAS phenol and GRAS acetate; (xxiv) GRAS acetate and GRAS phenol; (xxv) GRAS acetate and GRAS acid; (xxvi) GRAS acetate and GRAS aldehyde; (xxvii) GRAS acetate, GRAS alcohol and GRAS acid; (xxviii) GRAS acetate, GRAS aldehyde and GRAS acid; (xxix) GRAS acetate, GRAS phenol and GRAS acid; (xxx) GRAS acetate, GRAS alcohol, GRAS aldehyde and GRAS acid; (xxxi) GRAS acetate, GRAS alcohol, GRAS phenol and GRAS acid; (xxxii) GRAS acetal, GRAS alcohol and GRAS aldehyde; (xxxiii) GRAS acetal and GRAS phenol; (xxxiv) GRAS acetal and GRAS acid; (xxxv) GRAS acetal and GRAS alcohol; (xxxvi) GRAS acetal, GRAS alcohol and GRAS acid; (xxxvii) GRAS ester, GRAS alcohol, GRAS terpene and GRAS acid; (xxxviii) GRAS ester, GRAS alcohol and GRAS aldehyde; (xxxix) GRAS ester and GRAS acid; (xl) GRAS ester and GRAS phenol; (xli) GRAS ester and GRAS acetate; (xlii) GRAS ester and GRAS aldehyde; (xliii) GRAS ester, GRAS alcohol and GRAS acid; (xliv) GRAS terpene, GRAS alcohol and GRAS acid; (xlv) GRAS terpene, GRAS alcohol and GRAS aldehyde; (xlvi) GRAS terpene, GRAS ester, GRAS alcohol and GRAS acid; (xlvii) GRASs terpene, GRAS ester, GRAS alcohol and GRAS aldehyde; (xlviii) GRAS polyphenol, GRAS alcohol and GRAS acid; (xlix) GRAS terpene and GRAS acid; (l) GRAS terpene and GRAS phenol; (li) GRAS terpene and GRAS acetate; (lii) GRAS terpene and GRAS aldehyde; and (liii) GRAS polyphenol, GRAS alcohol and GRAS aldehyde.
19. The method according to claim 18 , wherein
(a) said GRAS alcohols are selected from acetoin, ethanol, 1-propanol, 2-propanol, propylene glycol, glycerol, n-butyl alcohol, iso-butyl alcohol, hexyl alcohol, L-menthol, octyl alcohol, cinnamyl alcohol, heptyl alcohol, 1-pentanol, 3-methyl-1-butanol, anisic alcohol, citronellol, n-decanol, geraniol, 3-hexenol, linalool, nerolidol, 2,6-nonadiene-1-ol, nonyl alcohol, rhodinol, terpineol, borneol, clineol, cuminyl alcohol, 10-undecene-1-ol, and 1-hexadecanol;
(b) said GRAS aldehydes are selected from acetaldehyde, anisic aldehyde, benzaldehyde, methyl-1-propanol, citral, citronellal, n-decanal, ethylvanillin, furfural, heliotropin, heptanal, hexanal, 2-hexenal, 3-phenyl-1-propanal, dodecanal, nonyl aldehyde, octyl aldehyde, phenylacetaldehyde, propanal, vanillin, cinnamic aldehyde, perillaldehyde, and cuminaldehyde;
(c) said GRAS phenols are selected from thymol, methyleugenol, acetyleugenol, safrol, eugenol, isoeugenol, anethole, phenol, methylchavicol, carvacrol, α-bisabolol, fornesol, anisole, and propenylguaethol;
(d) said GRAS acetates are selected from iso-amyl acetate, benzyl acetate, benzylphenyl acetate, n-butyl acetate, cinnamyl acetate, citronellyl acetate, ethyl acetate, eugenol acetate, geranyl acetate, hexyl acetate, hydrocinnamyl acetate, linalyl acetate, octyl acetate, phenylethyl acetate, terpinyl acetate, triacetin, potassium acetate, sodium acetate, and calcium acetate;
(e) said GRAS acids are selected from acetic acid, aconitic acid, adipic acid, formic acid, malic acid, capronic acid, 3-phenyl-1-propionic acid, nonanoic acid, lactic acid, phenoxyacetic acid, phenylacetic acid, valeric acid, iso-valeric acid, cinnamic acid, citric acid, mandelic acid, tartaric acid, fumaric acid, tannic acid, and/or their physiologically acceptable salts;
(f) said GRAS terpenes are selected from camphor, limonene, and β-caryophyllene; and
(g) said GRAS acetals are selected from acetal, acetaldehyde dibutyl acetal, acetaldehyde dipropyl acetal, acetaldehyde phenethyl propyl acetal, cinnamic aldehyde ethylene glycol acetal, decanal dimethyl acetal, heptanal dimethyl acetal, heptanal glyceryl acetal, and benzaldehyde propylene glycol acetal.
20. The method according to claim 18 , wherein said processing aid has a microbicidal activity period of less than 24 hours.
21. The method according to claim 3, wherein the microbicidal activity period of said processing aids is below 1 hour.
22. The method according to claim 18 , comprising the step of treating the products with said processing aid by means of brushing, spreading, emulsifying, spraying, nebulizing and/or volatizing the processing aid and/or during the separating, cleaning and/or cutting of the product.
23. The method according to claim 18 , wherein said processing aid contains less than 50% by weight of isopropanol or of a mixture of ethanol and isopropanol.
24. The method according to claim 18, wherein the proportion of flavoring agents in said processing aid is from 0.05 to 100% by weight.
25. The method according to claim 24 , wherein the proportion of flavoring agents in said processing aid is 100% by weight.
26. A microbicidal composition comprising at least two microbicidally active GRAS (generally recognized as safe) flavoring agents, said at least two GRAS flavoring agents being selected from the following group of combinations of GRAS flavoring agents:
(i) GRAS alcohol and GRAS aldehyde; (ii) GRAS alcohol, GRAS aldehyde and GRAS phenol; (iii) GRAS alcohol and GRAS phenol; (iv) GRAS aldehyde and GRAS phenol; (v) GRAS alcohol and GRAS acid; (vi) GRAS alcohol, GRAS aldehyde and GRAS acid; (vii) GRAS alcohol, GRAS aldehyde, GRAS phenol and GRAS acid; (viii) GRAS aldehyde and GRAS acid; (ix) GRAS alcohol, GRAS phenol and GRAS acid; (x) GRAS aldehyde, GRAS phenol and GRAS acid; (xi) GRAS alcohol and GRAS acetate; (xii) GRAS alcohol, GRAS aldehyde and GRAS acetate; (xiii) GRAS alcohol and GRAS alcohol; (xiv) GRAS aldehyde and GRAS aldehyde; (xv) GRAS acetate and GRAS acetate; (xvi) GRAS acetal and GRAS acetal; (xvii) GRAS phenol and GRAS phenol; (xviii) GRAS acid and GRAS acid; (xix) GRAS ester and GRAS ester; (xx) GRAS terpene and GRAS terpene; (xxi) GRAS phenol and GRAS polyphenol; (xxii) GRAS alcohol, GRAS aldehyde, GRAS phenol, GRAS acid and GRAS acetate; (xxiii) GRAS alcohol, GRAS aldehyde, GRAS phenol and GRAS acetate; (xxiv) GRAS acetate and GRAS phenol; (xxv) GRAS acetate and GRAS acid; (xxvi) GRAS acetate and GRAS aldehyde; (xxvii) GRAS acetate, GRAS alcohol and GRAS acid; (xxviii) GRAS acetate, GRAS aldehyde and GRAS acid; (xxix) GRAS acetate, GRAS phenol and GRAS acid; (xxx) GRAS acetate, GRAS alcohol, GRAS aldehyde and GRAS acid; (xxxi) GRAS acetate, GRAS alcohol, GRAS phenol and GRAS acid; (xxxii) GRAS acetal, GRAS alcohol and GRAS aldehyde; (xxxiii) GRAS acetal and GRAS phenol; (xxxiv) GRAS acetal and GRAS acid; (xxxv) GRAS acetal and GRAS alcohol; (xxxvi) GRAS acetal, GRAS alcohol and GRAS acid; (xxxvii) GRAS ester, GRAS alcohol, GRAS terpene and GRAS acid; (xxxviii) GRAS ester, GRAS alcohol and GRAS aldehyde; (xxxix) GRAS ester and GRAS acid; (xl) GRAS ester and GRAS phenol; (xli) GRAS ester and GRAS acetate; (xlii) GRAS ester and GRAS aldehyde; (xliii) GRAS ester, GRAS alcohol and GRAS acid; (xliv) GRAS terpene, GRAS alcohol and GRAS acid; (xlv) GRAS terpene, GRAS alcohol and GRAS aldehyde; (xlvi) GRAS terpene, GRAS ester, GRAS alcohol and GRAS acid; (xlvii) GRASs terpene, GRAS ester, GRAS alcohol and GRAS aldehyde; (xlviii) GRAS polyphenol, GRAS alcohol and GRAS acid; (xlix) GRAS terpene and GRAS acid; (l) GRAS terpene and GRAS phenol; (li) GRAS terpene and GRAS acetate; (lii) GRAS terpene and GRAS aldehyde; and (liii) GRAS polyphenol, GRAS alcohol and GRAS aldehyde.
27. A processing aid for treating the surface of microbially perishable products by means of brushing, spreading, emulsifying, spraying, nebulizing and/or volatizing and/or during the separating, cleaning and/or cutting of the products, said processing aid comprising a microbicidal composition comprising at least two microbicidally active GRAS (generally recognized as safe) flavoring agents, said at least two GRAS flavoring agents being selected from the following group of combinations of GRAS flavoring agents:
(i) GRAS alcohol and GRAS aldehyde; (ii) GRAS alcohol, GRAS aldehyde and GRAS phenol; (iii) GRAS alcohol and GRAS phenol; (iv) GRAS aldehyde and GRAS phenol; (v) GRAS alcohol and GRAS acid; (vi) GRAS alcohol, GRAS aldehyde and GRAS acid; (vii) GRAS alcohol, GRAS aldehyde, GRAS phenol and GRAS acid; (viii) GRAS aldehyde and GRAS acid; (ix) GRAS alcohol, GRAS phenol and GRAS acid; (x) GRAS aldehyde, GRAS phenol and GRAS acid; (xi) GRAS alcohol and GRAS acetate; (xii) GRAS alcohol, GRAS aldehyde and GRAS acetate; (xiii) GRAS alcohol and GRAS alcohol; (xiv) GRAS aldehyde and GRAS aldehyde; (xv) GRAS acetate and GRAS acetate; (xvi) GRAS acetal and GRAS acetal; (xvii) GRAS phenol and GRAS phenol; (xviii) GRAS acid and GRAS acid; (xix) GRAS ester and GRAS ester; (xx) GRAS terpene and GRAS terpene; (xxi) GRAS phenol and GRAS polyphenol; (xxii) GRAS alcohol, GRAS aldehyde, GRAS phenol, GRAS acid and GRAS acetate; (xxiii) GRAS alcohol, GRAS aldehyde, GRAS phenol and GRAS acetate; (xxiv) GRAS acetate and GRAS phenol; (xxv) GRAS acetate and GRAS acid; (xxvi) GRAS acetate and GRAS aldehyde; (xxvii) GRAS acetate, GRAS alcohol and GRAS acid; (xxviii) GRAS acetate, GRAS aldehyde and GRAS acid; (xxix) GRAS acetate, GRAS phenol and GRAS acid; (xxx) GRAS acetate, GRAS alcohol, GRAS aldehyde and GRAS acid; (xxxi) GRAS acetate, GRAS alcohol, GRAS phenol and GRAS acid; (xxxii) GRAS acetal, GRAS alcohol and GRAS aldehyde; (xxxiii) GRAS acetal and GRAS phenol; (xxxiv) GRAS acetal and GRAS acid; (xxxv) GRAS acetal and GRAS alcohol; (xxxvi) GRAS acetal, GRAS alcohol and GRAS acid; (xxxvii) GRAS ester, GRAS alcohol, GRAS terpene and GRAS acid; (xxxviii) GRAS ester, GRASalcohol and GRAS aldehyde; (xxxix) GRAS esterand GRAS acid; (xl) GRAS ester and GRAS phenol; (xli) GRAS ester and GRAS acetate; (xlii) GRAS ester and GRAS aldehyde; (xliii) GRAS ester, GRAS alcohol and GRAS acid; (xliv) GRAS terpene, GRAS alcohol and GRAS acid; (xlv) GRAS terpene, GRAS alcohol and GRAS aldehyde; (xlvi) GRAS terpene, GRAS ester, GRAS alcohol and GRAS acid; (xlvii) GRASs terpene, GRAS ester, GRAS alcohol and GRAS aldehyde; (xlviii) GRAS polyphenol, GRAS alcohol and GRAS acid; (xlix) GRAS terpene and GRAS acid; (l) GRAS terpene and GRAS phenol; (li) GRAS terpene and GRAS acetate; (lii) GRAS terpene and GRAS aldehyde; and (liii) GRAS polyphenol, GRAS alcohol and GRAS aldehyde.
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US11/522,667 US20070087094A1 (en) | 1995-03-31 | 2006-09-18 | Process for improving the durability of, and/or stabilizing, microbially perishable products |
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DEDE19512147.3 | 1995-03-31 | ||
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WOPCT/EP96/01364 | 1996-03-28 | ||
PCT/EP1996/001364 WO1996029895A1 (en) | 1995-03-31 | 1996-03-28 | Process for improving the shelf life of and/or stabilising products which can spoil under the action of microbes |
US73765597A | 1997-02-18 | 1997-02-18 | |
US09/620,872 US6514551B1 (en) | 1995-03-31 | 2000-07-21 | Process for improving the durability of, and/or stabilizing, microbially perishable products |
US10/357,726 US7108879B2 (en) | 1995-03-31 | 2003-02-04 | Process for improving the durability of, and/or stabilizing, microbially perishable products |
US11/522,667 US20070087094A1 (en) | 1995-03-31 | 2006-09-18 | Process for improving the durability of, and/or stabilizing, microbially perishable products |
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US10/357,726 Expired - Fee Related US7108879B2 (en) | 1995-03-31 | 2003-02-04 | Process for improving the durability of, and/or stabilizing, microbially perishable products |
US11/522,667 Abandoned US20070087094A1 (en) | 1995-03-31 | 2006-09-18 | Process for improving the durability of, and/or stabilizing, microbially perishable products |
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WO2016130990A1 (en) * | 2015-02-13 | 2016-08-18 | Hydromer Inc. | Antimicrobial formulations and methods for sanitizing meat products |
TWI548348B (en) * | 2011-10-20 | 2016-09-11 | 安麗托克斯公司 | Antimicrobial formulations with pelargonic acid |
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DK0762837T3 (en) | 1995-03-31 | 2002-06-10 | Schuer Joerg Peter Prof | Process for improving shelf life and stabilizing products that can be spoiled by microorganisms |
US20020176882A1 (en) * | 1997-06-23 | 2002-11-28 | Schur Jorg Peter | Additive the improvement and/or stabilization of the keeping quality of microbially perishable products |
DE19726429A1 (en) * | 1997-06-23 | 1998-12-24 | Schuer Joerg Peter Prof | Process and additive to improve the shelf life and / or stabilize microbially perishable products |
DE19831309A1 (en) * | 1998-07-13 | 2000-01-27 | Schuer Joerg Peter | Antimicrobial composition containing a mixture of hydrophilic and hydrophobic GRAS flavorings, useful for protecting foodstuffs, pharmaceuticals, cosmetics, dyes, paper and/or celluloses |
DE19831306A1 (en) * | 1998-07-13 | 2000-01-27 | Schuer Joerg Peter | Antimicrobial composition containing a mixture of hydrophilic and hydrophobic GRAS flavorings, useful for protecting foodstuffs, pharmaceuticals, cosmetics, dyes, paper and/or celluloses |
DE19831288A1 (en) * | 1998-07-13 | 2000-01-27 | Schuer Joerg Peter | Antimicrobial composition containing a mixture of hydrophilic and hydrophobic GRAS flavorings, useful for protecting foodstuffs, pharmaceuticals, cosmetics, dyes, paper and/or celluloses |
DK1096865T3 (en) * | 1998-07-13 | 2006-03-20 | Joerg Peter Schuer | Antimicrobial composition |
US6139890A (en) * | 1998-07-21 | 2000-10-31 | Bio-Tek Industries, Inc. | Method of extending the shelf life and/or reducing level of bacterial contamination on fruits and vegetables |
DE19851778C2 (en) * | 1998-11-10 | 2001-02-15 | Weller Frank Uwe | Combination of a liquid-tight meat tray with an inserted suction separation layer |
DE19931185A1 (en) | 1999-07-07 | 2001-01-18 | Joerg Peter Schuer | Air disinfection process |
DE19940283A1 (en) * | 1999-08-25 | 2001-03-01 | Joerg Peter Schuer | plant protection |
DE19940605A1 (en) * | 1999-08-27 | 2001-03-01 | Joerg Peter Schuer | impregnation process |
NL1013448C2 (en) * | 1999-11-01 | 2001-05-09 | Nl I Voor Zuivelonderzoek | Use of nonanoic acid as an anti-fungal agent. |
AU2791302A (en) * | 2000-11-09 | 2002-05-21 | Jorg P Schur | Synergistic medicament containing aromatic agents and having an antagonistic, regenerative and/or protagonist decontamination effect |
FR2817242B1 (en) * | 2000-11-30 | 2003-06-27 | Cebal | FLEXIBLE TUBES CONTAINING BIOCIDAL AGENTS |
CN1406194A (en) * | 2000-11-30 | 2003-03-26 | 塞巴尔股份有限公司 | Containers comprising a wall containing biocidal agents |
JP2002179509A (en) * | 2000-12-12 | 2002-06-26 | Takasago Internatl Corp | Antifugal perfume composition |
DE20100121U1 (en) * | 2001-01-05 | 2002-05-16 | Schuer Joerg Peter | Device for enriching air with air treatment agent |
DE10100595A1 (en) * | 2001-01-09 | 2002-07-18 | Joerg Peter Schuer | Process for non-toxic odor neutralization of air |
DK174676B1 (en) * | 2001-01-18 | 2003-08-25 | Slagteriernes Forskningsinst | Process and plant for the production of sliced food |
US20030031588A1 (en) * | 2001-06-13 | 2003-02-13 | Schur Jorg Peter | Device for enriching air with an air treatment agent, especially for the disinfection of air, and/or perfuming of air and/or for odor masking |
US20030228402A1 (en) * | 2002-02-19 | 2003-12-11 | Franklin Lanny U. | Compositions and methods for preservation of food |
AU2003223183A1 (en) * | 2002-02-19 | 2003-09-09 | Eden Researach Plc | Improvement of indoor air quality and antiseptic composition for use therein |
WO2003086109A1 (en) * | 2002-04-08 | 2003-10-23 | Kalsec, Incorporated | Labiatae herb extract compositions readily dispersible in cold brine |
WO2004073424A1 (en) * | 2003-02-14 | 2004-09-02 | Preservation Sciences, Inc. | Food and beverage preservative |
EP1615502B1 (en) * | 2003-04-08 | 2016-03-23 | Xeda International | Method for processing fruits and vegetables on the base of lecithin |
FR2853495B1 (en) * | 2003-04-08 | 2006-08-11 | Xeda International | PROCESS FOR TREATING FRUIT AND VEGETABLES BASED ON LECITHIN |
US20050196492A1 (en) * | 2004-03-04 | 2005-09-08 | Muller Wayne S. | Food preservative method and system using vanillin and constituent having isothiocynate compound |
FR2867948B1 (en) * | 2004-03-29 | 2008-02-22 | Hightech Bio Activities Holdin | DECONTAMINANT COMPOSITION HAVING BACTERICIDAL, FUNGICIDAL AND VIRUCID PROPERTIES, METHODS OF OBTAINING AND USE OF SUCH A COMPOSITION |
FR2876586B1 (en) * | 2004-10-20 | 2007-10-12 | Persee Medica | COMPOSITION FOR PREVENTING OR TREATING STRESS, INCLUDING CHRONIC AND PERMANENT STRESS BURNS |
JP4354392B2 (en) * | 2004-12-13 | 2009-10-28 | 理研ビタミン株式会社 | Process for producing modified natural intestine |
US20080260876A1 (en) * | 2005-04-01 | 2008-10-23 | Nicole Benhamou | Garlic Extract Compositions, Uses And Preparations Thereof |
DE102006018544A1 (en) * | 2006-04-21 | 2007-10-25 | Mayr-Melnhof Karton Ag | Packaging and use of fragrances in a package |
US8716200B2 (en) | 2006-09-13 | 2014-05-06 | Ecolab Usa Inc. | Conveyor lubricants including emulsion of a lipophilic compound and an emulsifier and/or an anionic surfactant and methods employing them |
AR064778A1 (en) * | 2007-01-12 | 2009-04-22 | Albemarle Corp | BIOCIDES BASED ON SPRAY SUITABLE FOR FOOD PROCESSING |
RU2476083C2 (en) * | 2007-08-29 | 2013-02-27 | Марс, Инкорпорейтед | Single-portion cat fodder and fodder production method |
US8329618B1 (en) | 2009-05-12 | 2012-12-11 | Aceto Agricultural Chemical Corporation | Tuber treatment composition |
US20100291265A1 (en) * | 2009-05-18 | 2010-11-18 | Board Of Trustees Of Michigan State University | Baking composition |
EP2301368A1 (en) | 2009-09-08 | 2011-03-30 | Mars, Incorporated | Composition for prevention against spoilage by microorganisms and uses and products related thereto |
US8293299B2 (en) | 2009-09-11 | 2012-10-23 | Kraft Foods Global Brands Llc | Containers and methods for dispensing multiple doses of a concentrated liquid, and shelf stable Concentrated liquids |
JP5907655B2 (en) * | 2009-12-21 | 2016-04-26 | テーブルマーク株式会社 | Food preservative, method for inhibiting mold and / or yeast growth, method for inhibiting yeast and / or bacterial growth |
ES2357389B1 (en) * | 2011-03-11 | 2011-09-26 | Biofungitek, Sociedad Limitada | FUNGICIDE AND BACTERICIDE COMPOSITION THAT INCLUDES VOLATILE ORGANIC COMPOUNDS OF NATURAL ORIGIN. |
US10044598B2 (en) | 2011-07-11 | 2018-08-07 | Sony Corporation | Network proxying technology |
US11013248B2 (en) | 2012-05-25 | 2021-05-25 | Kraft Foods Group Brands Llc | Shelf stable, concentrated, liquid flavorings and methods of preparing beverages with the concentrated liquid flavorings |
CA2892602C (en) * | 2012-12-05 | 2021-04-13 | Kemin Industries, Inc. | Pet food palatability enhancer with antimicrobial properties based on organic acids |
EP2995201A1 (en) * | 2014-09-04 | 2016-03-16 | Purac Biochem B.V. | Preservation of meat products with a composition comprising a vanilin and a cinnamate component |
TN2018000095A1 (en) * | 2015-09-30 | 2019-07-08 | Instituto Tecnologico Del Embalaje Transp Y Logistica Itene | Antimicrobial composition comprising citral, hexanal and linalool as active ingredients and application in packaging minimally processed fruits or vegetables |
US11793215B1 (en) * | 2018-09-07 | 2023-10-24 | Incuvator Fund I, Llc | Production of finish feed product and feed ingredient from viscera |
EP3747280A1 (en) * | 2019-06-07 | 2020-12-09 | Lucta, S.A. | Antimicrobial combination for use in animal feeds |
Citations (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1331331A (en) * | 1919-01-03 | 1920-02-17 | Erslev Knud | Process for improving tobacco |
US1790596A (en) * | 1927-05-16 | 1931-01-27 | Claude B Schneible | Column |
US2409088A (en) * | 1943-07-09 | 1946-10-08 | Weits John | Device for washing and conditioning air and gases |
US2496281A (en) * | 1944-07-12 | 1950-02-07 | Whiting Corp | Fly ash and dust collector |
US2596106A (en) * | 1947-11-22 | 1952-05-13 | Claude B Schneible | Column apparatus |
US2683074A (en) * | 1949-11-28 | 1954-07-06 | York Corp | Process for deodorizing and sterilizing air |
US2886297A (en) * | 1956-12-26 | 1959-05-12 | Phillips Petroleum Co | Brine creaming of latices |
US3191363A (en) * | 1961-04-07 | 1965-06-29 | Carrier Corp | Apparatus for treating air |
US3363403A (en) * | 1963-12-02 | 1968-01-16 | Pierre Georges Vicard | Electrostatic filtering apparatus |
US3442602A (en) * | 1964-07-09 | 1969-05-06 | Charles C Diehl | Method and mechanism for deodorizing polluted atmospheric air |
US3518096A (en) * | 1965-10-06 | 1970-06-30 | Stella Layton | Food preserving process |
US3557535A (en) * | 1968-11-25 | 1971-01-26 | Poma Inc | Air washer |
US3788045A (en) * | 1971-09-13 | 1974-01-29 | Peabody Engineering Corp | Gas cleaning apparatus |
US3908031A (en) * | 1973-03-12 | 1975-09-23 | Heller And Co B | Ethanol vapor sterilization of natural spices and other foods |
US3989485A (en) * | 1973-09-13 | 1976-11-02 | Intensa, S.A. | Process and apparatus for scrubbing exhaust gas from cyclone collectors |
US4110430A (en) * | 1974-02-02 | 1978-08-29 | Haarmann & Reimer Gmbh | A method of deodorizing |
US4200442A (en) * | 1976-12-03 | 1980-04-29 | Centre De Recherche Fondamentale "Rivieren" S.P.R.L. | Apparatus for neutralizing and purifying air |
US4361554A (en) * | 1981-05-06 | 1982-11-30 | Texas Botanical Research, Company | Organic insecticide |
US4446161A (en) * | 1982-03-29 | 1984-05-01 | General Foods Corporation | Aromatic, monohydric alcohols as preservatives for foods |
US4512935A (en) * | 1983-01-25 | 1985-04-23 | Tetra Pak International Ab | Apparatus for the volatilization of a liquid |
US4544666A (en) * | 1983-04-22 | 1985-10-01 | Phyton/Ag, Inc. | Chemotherapeutic agents for the control of plant diseases |
US4579569A (en) * | 1982-10-14 | 1986-04-01 | Fume-Klean | Apparatus for neutralizing and removing fumes |
US4602011A (en) * | 1975-10-24 | 1986-07-22 | Chapman Chemical Company | Antimicrobial compositions and methods of using same |
US4624688A (en) * | 1983-11-29 | 1986-11-25 | Oy A W Enbom Ab | Device for the purification of gases |
US4647458A (en) * | 1981-09-25 | 1987-03-03 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Liquid bactericide for foods and food processing machines or utensils, employing a synergistic mixture of ethyl alcohol, an organic acid and phosphoric acid |
US4806526A (en) * | 1984-07-11 | 1989-02-21 | University Of Sydney | Antiallergenic agent |
US4808396A (en) * | 1986-08-28 | 1989-02-28 | Ricoh Company, Ltd. | Ozone decomposing agent |
US4810268A (en) * | 1985-11-07 | 1989-03-07 | Ppg Industries, Inc. | Apparatus and method of washing air |
US4927651A (en) * | 1988-10-07 | 1990-05-22 | Kabushiki Kaisha Nasa | Method of preserving food |
US4977142A (en) * | 1984-07-11 | 1990-12-11 | University Of Sydney | Antiallergenic agent |
US5030253A (en) * | 1988-05-31 | 1991-07-09 | Shimizu Construction Co., Ltd. | Fragrant air supplying method and supplying system |
US5089268A (en) * | 1990-05-02 | 1992-02-18 | Katz David P | Egg phosphatide lipid emulsions altered for a specific therapeutic fatty acid composition |
US5091405A (en) * | 1987-01-05 | 1992-02-25 | E. I. Du Pont De Nemours And Company | Insecticidal pyrazolines |
US5143720A (en) * | 1990-11-28 | 1992-09-01 | Microcide, Inc. | Disinfecting and sanitizing compositions |
US5201919A (en) * | 1991-12-17 | 1993-04-13 | Inline Scrubber Corporation | Integral in-line gas scrubber |
US5322689A (en) * | 1992-03-10 | 1994-06-21 | The Procter & Gamble Company | Topical aromatic releasing compositions |
US5348187A (en) * | 1989-04-26 | 1994-09-20 | Alfa Institut Fur Hauswirtschaftliche Produkt- And Verfahrens- Entwicklung Gmbh | Double-walled cooking pot |
US5362520A (en) * | 1993-08-23 | 1994-11-08 | Rodriguez Ricardo M | Bleaching and finishing composition and method |
US5397385A (en) * | 1994-03-28 | 1995-03-14 | Watts; James L. | Anti-fouling coating composition containing capsaicin |
US5416075A (en) * | 1993-11-30 | 1995-05-16 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Biospecific emulsions |
US5439690A (en) * | 1993-05-21 | 1995-08-08 | Ecosmart, Inc. | Non-hazardous pest control |
US5472684A (en) * | 1993-06-02 | 1995-12-05 | Colgate Palmolive Company | Oral compositions for plaque and gingivitis |
US5474774A (en) * | 1994-03-25 | 1995-12-12 | Jlb, Inc. | Adhesion inhibiting composition |
US5480591A (en) * | 1994-03-16 | 1996-01-02 | Prodifa (S.A.R.L.) | Dynamic diffuser of a substance such as a perfume |
US5480519A (en) * | 1995-02-06 | 1996-01-02 | Texas Instruments Incorporated | Electrochemical etch system and method |
US5527552A (en) * | 1993-04-01 | 1996-06-18 | Kalamazoo Holdings, Inc. | Lipid-soluble green tea catechin antioxidant solutions |
US5547540A (en) * | 1993-08-03 | 1996-08-20 | Bdag Balcke-Durr Aktiengesellschaft | Device for cooling gases and optionally drying solid particles added to the gas |
US5569461A (en) * | 1995-02-07 | 1996-10-29 | Minnesota Mining And Manufacturing Company | Topical antimicrobial composition and method |
US5661104A (en) * | 1996-06-11 | 1997-08-26 | Givaudan-Roure (International) Sa | Preservative compositions for use in aqueous systems |
US5665432A (en) * | 1994-03-29 | 1997-09-09 | Takeda Chemical Industries, Ltd. | Process for treating timber |
US5686082A (en) * | 1992-12-24 | 1997-11-11 | L'oreal | Cosmetic or pharmaceutical composition containing a combination of a polyphenol and a ginkgo extract |
US5695801A (en) * | 1993-05-26 | 1997-12-09 | Cpc International Inc. | Method of making shelf stable moist pasta |
US5747416A (en) * | 1993-07-08 | 1998-05-05 | Mcardle; Blaise | Herbicidal and insecticidal protein-polysaccharide delivery compositions and methods for controlling plant and insect populations |
US5750563A (en) * | 1993-10-28 | 1998-05-12 | Sansho Seiyaku Co., Ltd. | Preparation for epidermis |
US5766314A (en) * | 1992-11-13 | 1998-06-16 | France Grignotage | Process and device for treating working atmosphere using a cyclone exchanger |
US5814325A (en) * | 1993-03-24 | 1998-09-29 | The Rod Family Trust | Process for repelling and killing insects and compositions to effect the same comprising a monoterpene |
US5879683A (en) * | 1994-03-04 | 1999-03-09 | Royal Free Hospital School Of Medicine | Antibacterial agent containing tea extract or active fraction thereof and β-lactam antibiotic |
US6004569A (en) * | 1993-05-21 | 1999-12-21 | Ecosmart Technologies, Inc. | Non-hazardous pest control |
US6007055A (en) * | 1997-12-29 | 1999-12-28 | Schifftner; Kenneth C. | Gas and liquid contact apparatus |
US6033705A (en) * | 1998-07-08 | 2000-03-07 | Isaacs; Charles E. | Method for treating foodstuffs to reduce or prevent microbial activity |
US6159523A (en) * | 1995-11-24 | 2000-12-12 | Loders-Croklaan Bv | Composition based on fish oil |
US6207290B1 (en) * | 1998-04-07 | 2001-03-27 | Burlington Bio-Medical & Scientific Corp. | Antifoulant compositions and methods of treating wood |
US6284259B1 (en) * | 1997-11-12 | 2001-09-04 | The Procter & Gamble Company | Antimicrobial wipes which provide improved residual benefit versus Gram positive bacteria |
US20020014707A1 (en) * | 1997-07-11 | 2002-02-07 | Fls Miljo A/S | Method of flue gas conditioning and a flue gas conditioning device |
US20020176882A1 (en) * | 1997-06-23 | 2002-11-28 | Schur Jorg Peter | Additive the improvement and/or stabilization of the keeping quality of microbially perishable products |
US6514551B1 (en) * | 1995-03-31 | 2003-02-04 | Jorg Peter Schur | Process for improving the durability of, and/or stabilizing, microbially perishable products |
US20030031588A1 (en) * | 2001-06-13 | 2003-02-13 | Schur Jorg Peter | Device for enriching air with an air treatment agent, especially for the disinfection of air, and/or perfuming of air and/or for odor masking |
US6608102B1 (en) * | 1997-09-09 | 2003-08-19 | Rutgers, The State University Of New Jersey | Plant proanthocyanidin extract effective at inhibiting adherence of bacteria with P-type fimbriae to surfaces |
US20040101459A1 (en) * | 2001-01-09 | 2004-05-27 | Schur Jorg Peter | Method for neutralising odours in the air in a non-toxic manner |
US20050035472A1 (en) * | 2001-01-05 | 2005-02-17 | Schur Jorg Peter | Device for enriching air with an air treatment agent |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE515423A (en) | ||||
GB172993A (en) * | 1920-06-12 | 1921-12-12 | Robert Lauder Mackenzie Wallis | Improvements in and relating to the employment of antiseptic, disinfectant, or preservative agents |
GB790075A (en) | 1954-10-28 | 1958-02-05 | Irwin Irville Lubowe | Solubilizing of mineral, vegetable and animal oils for cosmetic and industrial purposes |
GB1060447A (en) * | 1963-05-14 | 1967-03-01 | Maple Leaf Trust | Compositions for the preservation of foodstuffs, for the sterilization and hygiene ofair in confined spaces and for cosmetic and pharmaceutical purposes |
FR1400428A (en) | 1964-03-18 | 1965-05-28 | Ajem Lab Inc | Air washer |
FR2228434A1 (en) | 1973-05-08 | 1974-12-06 | Delpech Lucien | Fungicides for treatment of plants or wood - contg. a natural or synthetic phenol |
DK137622B (en) * | 1973-05-15 | 1978-04-10 | Ivar Harry Sanick | Method and means of protection of food or stimulants against attack by microorganisms. |
JPS5332134A (en) | 1976-09-04 | 1978-03-27 | Katsuraya Fine Goods | Aromatic compound and its preparation method |
JPS5758876A (en) * | 1980-09-26 | 1982-04-08 | Ueno Seiyaku Kk | Germicide for food, raw ingredient of food, and device for processing food, and its use |
JPS57194775A (en) * | 1981-05-21 | 1982-11-30 | Asama Kasei Kk | Storing and quality improving agent of food |
EP0101083A1 (en) | 1981-09-22 | 1984-02-22 | Wilhelm O. H. Grunert | Process for neutralising irritants and toxic gases and for preparations suitable for carrying out the process |
DE3138288A1 (en) | 1981-09-25 | 1983-04-07 | Siemens AG, 1000 Berlin und 8000 München | Arrangement and process for generating an electric charge image |
ATE59298T1 (en) | 1982-09-17 | 1991-01-15 | Human Oltoanyagtermelo | PREPARATIONS FOR THE TREATMENT OF SURFACE WOUNDS AND METHOD OF MAKING SUCH PREPARATIONS. |
JPS59172416A (en) | 1983-03-18 | 1984-09-29 | Terumo Corp | Fat transfusion solution |
SU1189454A1 (en) | 1983-05-19 | 1985-11-07 | Ural Vni Pi Khim Promy | Air refreshing agent |
JPS62111675A (en) * | 1985-11-08 | 1987-05-22 | Sanraku Inc | Food preservative |
JPH0724544B2 (en) | 1985-11-26 | 1995-03-22 | 三栄源エフ・エフ・アイ株式会社 | E. coli sterilization and freshness preservation of raw vegetables |
DE3721137A1 (en) | 1987-06-26 | 1989-01-05 | Dietl Hans | Fat emulsion for intravenous use |
DE3734147C2 (en) | 1987-10-09 | 1998-10-29 | Braun Melsungen Ag | Isotonic omega-3 fatty acid-containing fat emulsion and its use |
JPH02142703A (en) * | 1988-11-24 | 1990-05-31 | Kurita Water Ind Ltd | Controller against harmful organism |
CA2012288A1 (en) | 1989-03-16 | 1990-09-16 | Wolfgang Beilfuss | Plant hygiene disinfectant |
JPH0469308A (en) | 1990-07-06 | 1992-03-04 | Doi Kyohei | Centipede repellent |
JP3270559B2 (en) * | 1992-02-26 | 2002-04-02 | 三菱ウェルファーマ株式会社 | Composition containing allyl isothiocyanate and use thereof |
JP2660196B2 (en) * | 1992-04-17 | 1997-10-08 | 株式会社アラミック | Rice quality preservative |
US5574065A (en) | 1994-04-21 | 1996-11-12 | Clintec Nutrition Co. | Method and composition for normalizing injury response |
JPH0820510A (en) * | 1994-07-06 | 1996-01-23 | Kaneka San Supaisu:Kk | Spice having antimicrobial activity and antimicrobial agent prepared by using the same |
US6348187B1 (en) * | 1996-01-24 | 2002-02-19 | Warner-Lambert Company | Peroxide/essential oils containing mouthwash compositions and two-part mouthwash systems |
DE19617278A1 (en) | 1996-04-30 | 1997-11-13 | Hubert Dr Christ | Biodegradable universal cleaning agents for e.g. cleaning equipment used to make paper, board or pulp |
DE19726429A1 (en) | 1997-06-23 | 1998-12-24 | Schuer Joerg Peter Prof | Process and additive to improve the shelf life and / or stabilize microbially perishable products |
DE19831306A1 (en) | 1998-07-13 | 2000-01-27 | Schuer Joerg Peter | Antimicrobial composition containing a mixture of hydrophilic and hydrophobic GRAS flavorings, useful for protecting foodstuffs, pharmaceuticals, cosmetics, dyes, paper and/or celluloses |
DE19831288A1 (en) | 1998-07-13 | 2000-01-27 | Schuer Joerg Peter | Antimicrobial composition containing a mixture of hydrophilic and hydrophobic GRAS flavorings, useful for protecting foodstuffs, pharmaceuticals, cosmetics, dyes, paper and/or celluloses |
DK1096865T3 (en) | 1998-07-13 | 2006-03-20 | Joerg Peter Schuer | Antimicrobial composition |
DE19831309A1 (en) | 1998-07-13 | 2000-01-27 | Schuer Joerg Peter | Antimicrobial composition containing a mixture of hydrophilic and hydrophobic GRAS flavorings, useful for protecting foodstuffs, pharmaceuticals, cosmetics, dyes, paper and/or celluloses |
DE19850994A1 (en) | 1998-11-05 | 2000-05-11 | Menno Chemie Vertriebsges M B | Agent for the defense and inactivation of pathogens of plant roots, stalks, flowers, leaves and seeds |
DE19931185A1 (en) | 1999-07-07 | 2001-01-18 | Joerg Peter Schuer | Air disinfection process |
DE19940283A1 (en) | 1999-08-25 | 2001-03-01 | Joerg Peter Schuer | plant protection |
DE19940605A1 (en) | 1999-08-27 | 2001-03-01 | Joerg Peter Schuer | impregnation process |
EP1228769A1 (en) * | 2001-02-02 | 2002-08-07 | Jörg-Peter Prof. Schür | Symbiotic regenerative composition |
DE10128563A1 (en) | 2001-06-13 | 2003-01-02 | Joerg Peter Schuer | Device for enriching air with treatment agent, used e.g. in refrigerator or computer for disinfection and deodorization, has vessel containing liquid agent, vaporizer with inclined surface and excess liquid return unit |
WO2002101299A1 (en) | 2001-06-13 | 2002-12-19 | Schuer Joerg Peter | Device for enriching air with an air treatment agent, especially for sanitizing and/or scenting air and/or masking odors |
DE10141734A1 (en) | 2001-08-25 | 2003-03-06 | Joerg Peter Schuer | Device for enriching air with treatment agent, used e.g. in refrigerator or computer for disinfection and deodorization, has vessel containing liquid agent, vaporizer with inclined surface and excess liquid return unit |
-
1996
- 1996-03-28 DK DK96909141T patent/DK0762837T3/en active
- 1996-03-28 EP EP01109105A patent/EP1116446B1/en not_active Expired - Lifetime
- 1996-03-28 EP EP96909141A patent/EP0762837B1/en not_active Expired - Lifetime
- 1996-03-28 ES ES96909141T patent/ES2173274T3/en not_active Expired - Lifetime
- 1996-03-28 PT PT96909141T patent/PT762837E/en unknown
- 1996-03-28 AT AT01109105T patent/ATE544359T1/en active
- 1996-03-28 AU AU52750/96A patent/AU5275096A/en not_active Abandoned
- 1996-03-28 DE DE59608782T patent/DE59608782D1/en not_active Expired - Lifetime
- 1996-03-28 WO PCT/EP1996/001364 patent/WO1996029895A1/en active IP Right Grant
- 1996-03-28 DE DE19612340A patent/DE19612340A1/en not_active Ceased
- 1996-03-28 JP JP8528939A patent/JPH10501445A/en not_active Ceased
- 1996-03-28 AT AT96909141T patent/ATE213593T1/en not_active IP Right Cessation
-
2000
- 2000-07-21 US US09/620,872 patent/US6514551B1/en not_active Expired - Fee Related
-
2003
- 2003-02-04 US US10/357,726 patent/US7108879B2/en not_active Expired - Fee Related
-
2006
- 2006-09-18 US US11/522,667 patent/US20070087094A1/en not_active Abandoned
Patent Citations (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1331331A (en) * | 1919-01-03 | 1920-02-17 | Erslev Knud | Process for improving tobacco |
US1790596A (en) * | 1927-05-16 | 1931-01-27 | Claude B Schneible | Column |
US2409088A (en) * | 1943-07-09 | 1946-10-08 | Weits John | Device for washing and conditioning air and gases |
US2496281A (en) * | 1944-07-12 | 1950-02-07 | Whiting Corp | Fly ash and dust collector |
US2596106A (en) * | 1947-11-22 | 1952-05-13 | Claude B Schneible | Column apparatus |
US2683074A (en) * | 1949-11-28 | 1954-07-06 | York Corp | Process for deodorizing and sterilizing air |
US2886297A (en) * | 1956-12-26 | 1959-05-12 | Phillips Petroleum Co | Brine creaming of latices |
US3191363A (en) * | 1961-04-07 | 1965-06-29 | Carrier Corp | Apparatus for treating air |
US3363403A (en) * | 1963-12-02 | 1968-01-16 | Pierre Georges Vicard | Electrostatic filtering apparatus |
US3442602A (en) * | 1964-07-09 | 1969-05-06 | Charles C Diehl | Method and mechanism for deodorizing polluted atmospheric air |
US3518096A (en) * | 1965-10-06 | 1970-06-30 | Stella Layton | Food preserving process |
US3557535A (en) * | 1968-11-25 | 1971-01-26 | Poma Inc | Air washer |
US3788045A (en) * | 1971-09-13 | 1974-01-29 | Peabody Engineering Corp | Gas cleaning apparatus |
US3908031A (en) * | 1973-03-12 | 1975-09-23 | Heller And Co B | Ethanol vapor sterilization of natural spices and other foods |
US3989485A (en) * | 1973-09-13 | 1976-11-02 | Intensa, S.A. | Process and apparatus for scrubbing exhaust gas from cyclone collectors |
US4110430A (en) * | 1974-02-02 | 1978-08-29 | Haarmann & Reimer Gmbh | A method of deodorizing |
US4602011A (en) * | 1975-10-24 | 1986-07-22 | Chapman Chemical Company | Antimicrobial compositions and methods of using same |
US4200442A (en) * | 1976-12-03 | 1980-04-29 | Centre De Recherche Fondamentale "Rivieren" S.P.R.L. | Apparatus for neutralizing and purifying air |
US4361554A (en) * | 1981-05-06 | 1982-11-30 | Texas Botanical Research, Company | Organic insecticide |
US4647458A (en) * | 1981-09-25 | 1987-03-03 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Liquid bactericide for foods and food processing machines or utensils, employing a synergistic mixture of ethyl alcohol, an organic acid and phosphoric acid |
US4446161A (en) * | 1982-03-29 | 1984-05-01 | General Foods Corporation | Aromatic, monohydric alcohols as preservatives for foods |
US4579569A (en) * | 1982-10-14 | 1986-04-01 | Fume-Klean | Apparatus for neutralizing and removing fumes |
US4512935A (en) * | 1983-01-25 | 1985-04-23 | Tetra Pak International Ab | Apparatus for the volatilization of a liquid |
US4544666A (en) * | 1983-04-22 | 1985-10-01 | Phyton/Ag, Inc. | Chemotherapeutic agents for the control of plant diseases |
US4624688A (en) * | 1983-11-29 | 1986-11-25 | Oy A W Enbom Ab | Device for the purification of gases |
US4806526A (en) * | 1984-07-11 | 1989-02-21 | University Of Sydney | Antiallergenic agent |
US4977142A (en) * | 1984-07-11 | 1990-12-11 | University Of Sydney | Antiallergenic agent |
US4810268A (en) * | 1985-11-07 | 1989-03-07 | Ppg Industries, Inc. | Apparatus and method of washing air |
US4808396A (en) * | 1986-08-28 | 1989-02-28 | Ricoh Company, Ltd. | Ozone decomposing agent |
US5091405A (en) * | 1987-01-05 | 1992-02-25 | E. I. Du Pont De Nemours And Company | Insecticidal pyrazolines |
US5030253A (en) * | 1988-05-31 | 1991-07-09 | Shimizu Construction Co., Ltd. | Fragrant air supplying method and supplying system |
US4927651A (en) * | 1988-10-07 | 1990-05-22 | Kabushiki Kaisha Nasa | Method of preserving food |
US5348187A (en) * | 1989-04-26 | 1994-09-20 | Alfa Institut Fur Hauswirtschaftliche Produkt- And Verfahrens- Entwicklung Gmbh | Double-walled cooking pot |
US5089268A (en) * | 1990-05-02 | 1992-02-18 | Katz David P | Egg phosphatide lipid emulsions altered for a specific therapeutic fatty acid composition |
US5143720A (en) * | 1990-11-28 | 1992-09-01 | Microcide, Inc. | Disinfecting and sanitizing compositions |
US5201919A (en) * | 1991-12-17 | 1993-04-13 | Inline Scrubber Corporation | Integral in-line gas scrubber |
US5322689A (en) * | 1992-03-10 | 1994-06-21 | The Procter & Gamble Company | Topical aromatic releasing compositions |
US5766314A (en) * | 1992-11-13 | 1998-06-16 | France Grignotage | Process and device for treating working atmosphere using a cyclone exchanger |
US5686082A (en) * | 1992-12-24 | 1997-11-11 | L'oreal | Cosmetic or pharmaceutical composition containing a combination of a polyphenol and a ginkgo extract |
US5814325A (en) * | 1993-03-24 | 1998-09-29 | The Rod Family Trust | Process for repelling and killing insects and compositions to effect the same comprising a monoterpene |
US5527552A (en) * | 1993-04-01 | 1996-06-18 | Kalamazoo Holdings, Inc. | Lipid-soluble green tea catechin antioxidant solutions |
US5439690A (en) * | 1993-05-21 | 1995-08-08 | Ecosmart, Inc. | Non-hazardous pest control |
US6004569A (en) * | 1993-05-21 | 1999-12-21 | Ecosmart Technologies, Inc. | Non-hazardous pest control |
US5695801A (en) * | 1993-05-26 | 1997-12-09 | Cpc International Inc. | Method of making shelf stable moist pasta |
US5472684A (en) * | 1993-06-02 | 1995-12-05 | Colgate Palmolive Company | Oral compositions for plaque and gingivitis |
US5747416A (en) * | 1993-07-08 | 1998-05-05 | Mcardle; Blaise | Herbicidal and insecticidal protein-polysaccharide delivery compositions and methods for controlling plant and insect populations |
US5547540A (en) * | 1993-08-03 | 1996-08-20 | Bdag Balcke-Durr Aktiengesellschaft | Device for cooling gases and optionally drying solid particles added to the gas |
US5362520A (en) * | 1993-08-23 | 1994-11-08 | Rodriguez Ricardo M | Bleaching and finishing composition and method |
US5750563A (en) * | 1993-10-28 | 1998-05-12 | Sansho Seiyaku Co., Ltd. | Preparation for epidermis |
US5416075A (en) * | 1993-11-30 | 1995-05-16 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Biospecific emulsions |
US5879683A (en) * | 1994-03-04 | 1999-03-09 | Royal Free Hospital School Of Medicine | Antibacterial agent containing tea extract or active fraction thereof and β-lactam antibiotic |
US5480591A (en) * | 1994-03-16 | 1996-01-02 | Prodifa (S.A.R.L.) | Dynamic diffuser of a substance such as a perfume |
US5474774A (en) * | 1994-03-25 | 1995-12-12 | Jlb, Inc. | Adhesion inhibiting composition |
US5397385A (en) * | 1994-03-28 | 1995-03-14 | Watts; James L. | Anti-fouling coating composition containing capsaicin |
US5665432A (en) * | 1994-03-29 | 1997-09-09 | Takeda Chemical Industries, Ltd. | Process for treating timber |
US5480519A (en) * | 1995-02-06 | 1996-01-02 | Texas Instruments Incorporated | Electrochemical etch system and method |
US5569461A (en) * | 1995-02-07 | 1996-10-29 | Minnesota Mining And Manufacturing Company | Topical antimicrobial composition and method |
US6514551B1 (en) * | 1995-03-31 | 2003-02-04 | Jorg Peter Schur | Process for improving the durability of, and/or stabilizing, microbially perishable products |
US6159523A (en) * | 1995-11-24 | 2000-12-12 | Loders-Croklaan Bv | Composition based on fish oil |
US5661104A (en) * | 1996-06-11 | 1997-08-26 | Givaudan-Roure (International) Sa | Preservative compositions for use in aqueous systems |
US20020176882A1 (en) * | 1997-06-23 | 2002-11-28 | Schur Jorg Peter | Additive the improvement and/or stabilization of the keeping quality of microbially perishable products |
US20020014707A1 (en) * | 1997-07-11 | 2002-02-07 | Fls Miljo A/S | Method of flue gas conditioning and a flue gas conditioning device |
US6608102B1 (en) * | 1997-09-09 | 2003-08-19 | Rutgers, The State University Of New Jersey | Plant proanthocyanidin extract effective at inhibiting adherence of bacteria with P-type fimbriae to surfaces |
US6284259B1 (en) * | 1997-11-12 | 2001-09-04 | The Procter & Gamble Company | Antimicrobial wipes which provide improved residual benefit versus Gram positive bacteria |
US6007055A (en) * | 1997-12-29 | 1999-12-28 | Schifftner; Kenneth C. | Gas and liquid contact apparatus |
US6207290B1 (en) * | 1998-04-07 | 2001-03-27 | Burlington Bio-Medical & Scientific Corp. | Antifoulant compositions and methods of treating wood |
US6033705A (en) * | 1998-07-08 | 2000-03-07 | Isaacs; Charles E. | Method for treating foodstuffs to reduce or prevent microbial activity |
US20050035472A1 (en) * | 2001-01-05 | 2005-02-17 | Schur Jorg Peter | Device for enriching air with an air treatment agent |
US20040101459A1 (en) * | 2001-01-09 | 2004-05-27 | Schur Jorg Peter | Method for neutralising odours in the air in a non-toxic manner |
US20030031588A1 (en) * | 2001-06-13 | 2003-02-13 | Schur Jorg Peter | Device for enriching air with an air treatment agent, especially for the disinfection of air, and/or perfuming of air and/or for odor masking |
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Also Published As
Publication number | Publication date |
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EP0762837B1 (en) | 2002-02-27 |
ATE213593T1 (en) | 2002-03-15 |
EP0762837A1 (en) | 1997-03-19 |
WO1996029895A1 (en) | 1996-10-03 |
DE19612340A1 (en) | 1996-11-07 |
ATE544359T1 (en) | 2012-02-15 |
DE59608782D1 (en) | 2002-04-04 |
US7108879B2 (en) | 2006-09-19 |
AU5275096A (en) | 1996-10-16 |
US20030198718A1 (en) | 2003-10-23 |
PT762837E (en) | 2002-07-31 |
EP1116446A3 (en) | 2003-04-02 |
ES2173274T3 (en) | 2002-10-16 |
EP1116446A2 (en) | 2001-07-18 |
US6514551B1 (en) | 2003-02-04 |
EP1116446B1 (en) | 2012-02-08 |
JPH10501445A (en) | 1998-02-10 |
DK0762837T3 (en) | 2002-06-10 |
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