Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberUS20080269774 A1
Publication typeApplication
Application numberUS 11/924,369
Publication dateOct 30, 2008
Filing dateOct 25, 2007
Priority dateOct 26, 2006
Also published asUS8298244, US20100331853
Publication number11924369, 924369, US 2008/0269774 A1, US 2008/269774 A1, US 20080269774 A1, US 20080269774A1, US 2008269774 A1, US 2008269774A1, US-A1-20080269774, US-A1-2008269774, US2008/0269774A1, US2008/269774A1, US20080269774 A1, US20080269774A1, US2008269774 A1, US2008269774A1
InventorsAdrian Garcia, Ting Tina Ye, Quang Q. Tran, Bart Bojanowski, Alec Piplani, Aaron Lee Berez
Original AssigneeChestnut Medical Technologies, Inc.
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Intracorporeal Grasping Device
US 20080269774 A1
Abstract
An intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tube member having a distal end portion. An elongated core member is disposed with the interior cavity of the tubular member for rotational or slidably movement within the tubular member and the elongated core member having a proximal end portion and a distal end portion. The elongated core member comprises a uniform diameter tube having some flexibility at the proximal end portion and greater flexibility while along a longitudinal axis in a direction towards the distal end portion; and a grasping configuration is provided for capturing an object (e.g., clot or debris) therein and the assembly may have a proximal end secured to the distal end of the elongated core member. The configuration has an expanded and contracted configuration, and distal sections configured to grasp an object. The grasping configuration may be formed by at least one movable jaw attached to the distal end portion of the elongated core member and a length portion of the distal end portion of the tube member. The grasping configuration may include unitarily formed plurality of movable jaws attached to the distal end portion of the elongated core member. Further, the grasping configuration may be formed by a plurality of loop members attached to the distal end portion of the elongated core member. Further, the grasping configuration may be formed by at least one spiral member having a distal tip for penetrating an object to be removed from a human body lumen. The device has the spiral member provided at the distal end portion of the elongated core member. The grasping configuration can be formed by at least one web member for retaining an object to be removed from a human body lumen, the web member being provided at the distal end portion of the elongated core member.
Images(18)
Previous page
Next page
Claims(41)
1. An intracorporeal grasping device having a longitudinal axis, comprising:
an elongated core member having a proximal end portion and a distal end portion, the elongated core member comprising a generally uniform diameter tube having variable flexibility along a length from the proximal end portion to the distal end portion; and
a grasping assembly attached to the distal end portion of the elongated core member.
2. The intracorporeal grasping device of claim 1, wherein the distal portion of the core member is at least in part 10%-25% more flexible than the proximal portion of the core member.
3. The intracorporeal grasping device of claim 1, wherein the wherein the distal portion of the core member is at least in part 35%-50% more flexible than the proximal portion of the core member.
4. The intracorporeal grasping device of claim 1, wherein the tube further comprises a series of spaced circumferential slots at the distal end portion to provide variability flexibility of the tube.
5. The intracorporeal grasping device of claim 1, wherein the wherein an intermediate portion of the core member is defined between the distal end portion and the proximal end portion, the intermediate portion having greater flexibility than the proximal end portion of the core member, and the intermediate portion having less flexibility than the distal end portion of the core member.
6. The intracorporeal grasping device of claim 5, wherein the tube comprises a series of circumferential slots providing the distal end portion with greater flexibility than the intermediate portion.
7. The intracorporeal grasping device of claim 5, wherein the tube further comprises a series of circumferential slots, wherein a density of the slots is higher at the distal end portion than a density of slots at the proximal end portion.
8. The intracorporeal grasping device of claim 7, wherein there is a continuous transition along the length of the tube from higher density of slots to lower the density of slots.
9. The intracorporeal grasping device of claim 1, further comprising a uniform diameter core centered within the tube and spanning the length of the tube.
10. The intracorporeal grasping device of claim 9, wherein at least the ends of the core are radially attached to the tube.
11. The intracorporeal grasping device of claim 10, wherein the core is radially attached to the tube by at least one of soldering, welding or brazing.
12. An intracorporeal grasping device having a longitudinal axis, comprising:
a movable elongated core having a proximal end and a distal end, the elongated core comprising a plurality of flexion regions having different flexions along a length from the proximal end to the distal end portion; and
a grasping assembly attached to the distal end of the elongated core.
13. The intracorporeal grasping device of claim 12, wherein at least one flexion region of the core member is 10%-25% more flexible than another flexion region the core member.
14. The intracorporeal grasping device of claim 12, wherein the wherein at least one flexion region of the core member is 35%-50% more flexible than another flexion region. of the core member.
15. The intracorporeal grasping device of claim 12, wherein the flexion regions include plurality circumferential slots of different densities.
16. An intracorporeal grasping device, comprising:
a tubular member for entering a lumen of a human body and the tubular member having a distal end portion;
an elongated core member being disposed with the tubular member and the elongated core member having a proximal end portion and a distal end portion; and
a grasping configuration for capturing an object therein, in which the grasping configuration is formed by at least one spiral member having a distal tip for penetrating an object to be removed from a human body lumen, the spiral member being provided at the distal end portion of the elongated core member.
17. The grasping device according to claim 16, wherein the spiral member is configured to rotate by an axis to penetrate the object to be removed.
18. The grasping device according to claim 16, wherein the grasping configuration includes a moveable jaw type member.
19. The grasping device according to claim 18, wherein the grasping configuration is formed with tubing having at least one perforation for releasing a fluid from within the tubing.
20. The grasping device according to claim 16, wherein the elongated core member has variable flexibility along a length from the proximal end portion to the distal end portion.
21. The grasping device according to claim 16, wherein the tube further comprises a series of spaced circumferential slots at the distal end portion to provide variability flexibility of the tube.
22. The grasping device according to claim 16, wherein the wherein an intermediate portion of the core member is defined between the distal end portion and the proximal end portion, the intermediate portion having greater flexibility than the proximal end portion of the core member, and the intermediate portion having less flexibility than the distal end portion of the core member.
23. An intracorporeal grasping device, comprising:
a tubular member for entering a lumen of a human body and the tubular member having a distal end portion;
an elongated core member being disposed with the tubular member and the elongated core member having a proximal end portion and a distal end portion; and
a grasping configuration for capturing an object therein, in which the grasping configuration is formed by at least one web member retaining an object to be removed from a human body lumen, the web member being provided at the distal end portion of the elongated core member.
24. The grasping device according to claim 23, wherein the grasping configuration includes a moveable jaw type member attached to the web member.
25. The grasping device according to claim 24, wherein the grasping configuration is formed with tubing having a wall with at least one perforation for releasing a fluid from within the tubing.
26. The grasping device according to claim 25, wherein the jaws includes an engaging surface and an opposing surface, the engaging surface including a plurality of engaging elements provided along a longitudinal length thereof.
27. The grasping device according to claim 26, wherein the engaging elements are formed as ribs inwardly extending thereof.
28. The grasping device according to claim 23, wherein the elongated core member has variable flexibility along a length from the proximal end portion to the distal end portion.
29. An intracorporeal grasping device, comprising:
a tubular member for entering a lumen of a human body and the tubular member having a distal end portion;
an elongated core member being disposed with the tubular member and the elongated core member having a proximal end portion and a distal end portion; and
a grasping configuration for capturing an object therein, in which the grasping configuration is formed by at least one spiral member having a distal tip for penetrating an object to be removed from a human body lumen, the spiral member being provided at the distal end portion of the elongated core member.
30. The grasping device according to claim 29, wherein the spiral member is configured to rotate by an axis to penetrate the object to be removed.
31. The grasping device according to claim 29, wherein the grasping configuration includes a moveable jaw type member.
32. The grasping device according to claim 29, wherein the grasping configuration is formed with tubing having at least one perforation for releasing a fluid from within the tubing.
33. The grasping device according to claim 29, wherein the elongated core member has variable flexibility along a length from the proximal end portion to the distal end portion.
34. The grasping device according to claim 29, wherein the tube further comprises a series of spaced circumferential slots at the distal end portion to provide variability flexibility of the tube.
35. The grasping device according to claim 29, wherein the wherein an intermediate portion of the core member is defined between the distal end portion and the proximal end portion, the intermediate portion having greater flexibility than the proximal end portion of the core member, and the intermediate portion having less flexibility than the distal end portion of the core member.
36. An intracorporeal grasping device, comprising:
a tubular member for entering a lumen of a human body and the tubular member having a distal end portion;
an elongated core member being disposed with the tubular member and the elongated core member having a proximal end portion and a distal end portion; and
a grasping configuration for capturing an object therein, in which the grasping configuration is formed by at least one web member retaining an object to be removed from a human body lumen, the web member being provided at the distal end portion of the elongated core member.
37. The grasping device according to claim 36, wherein the grasping configuration includes a moveable jaw type member attached to the web member.
38. The grasping device according to claim 37, wherein the grasping configuration is formed with tubing having a wall with at least one perforation for releasing a fluid from within the tubing.
39. The grasping device according to claim 38, wherein the jaws includes an engaging surface and an opposing surface, the engaging surface including a plurality of engaging elements provided along a longitudinal length thereof.
40. The grasping device according to claim 39, wherein the engaging elements are formed as ribs inwardly extending thereof.
41. The grasping device according to claim 36, wherein the elongated core member has variable flexibility along a length from the proximal end portion to the distal end portion.
Description
    CROSS REFERENCE TO RELATED APPLICATIONS
  • [0001]
    This application claims the benefit of priority to Provisional Application 60/854,439 filed in the U.S. Patent and Trademark Office on Oct. 26, 2006. The content of the noted application is incorporated by reference in its entirety.
  • FIELD OF THE INVENTION
  • [0002]
    The invention pertains to an intracorporeal device and method for grasping objects within a patient's body and withdrawing the grasped objects from the patient's body. More specifically, the intracorporeal device is a grasping device having an internal shaft for removing an object, such as from a patient's vasculature.
  • BACKGROUND OF THE INVENTION
  • [0003]
    Developments in medical technology and associated treatments have been focused on clearing or removing thromboembolisms or “blood clots” from the cervical and cerebral vasculature in order to treat thromboembolic stroke victims. Thromboembolic stroke is a life threatening condition that consists of arrested blood flow to a region of the brain due to a thromboembolism blocking a blood vessel feeding that region. Such thrombi often originate in the left heart chambers, break free into the aorta and flow downstream into the cervical neck arteries e.g. carotid arteries, and then ultimately lodge into a narrowed vessel somewhere down the narrowing vascular tree of the cerebral arteries associated with the brain in the head. Once lodged, the thrombus occludes flow along the vessel downstream of the blockage, thus arresting blood flow to the downstream blood vessel and causing the stroke.
  • [0004]
    Several grasping device assemblies and methods have been disclosed specifically for removing thrombi from the cervical and cerebral vessels in order to treat thromboembolic stroke. However, many of these devices have grasping assemblies that are not well adopted for delivery to distal regions of the cerebral vessels where many thromboembolisms are known to cause a debilitating stroke.
  • [0005]
    U.S. Pat. No. 6,679,893 describes a grasping device for removing thrombi from the cervical and cerebral vessels in order to treat thromboembolic stroke. This patent describes several grasping assemblies that may be utilized in its device. However, it is desired to have more flexibility in the selection of grasping assemblies depending on the type and location of the thrombi.
  • [0006]
    When retrieving a neurovascular clot or foreign body, a device having a distal grasping end with greater flexibility is desired. It is also desired to have a distal grasping end that is easily manufactured based on the desired flexibility.
  • BRIEF SUMMARY OF THE INVENTION
  • [0007]
    The invention pertains to an intracorporeal device and method for grasping objects within lumen of a human body and withdrawing the grasped objects from the human body.
  • [0008]
    In one aspect, an intracorporeal grasping device includes an elongated core having a proximal end portion and a distal end portion. The elongated core includes a tube having a variable flexibility along a length from the proximal end portion to the distal end portion. A grasping configuration is disposed to the distal end portion of the elongated core member for grasping an object from a human body.
  • [0009]
    In another aspect, an intracorporeal grasping device includes a movable elongated core having a proximal end and a distal end. The elongated core includes a plurality of flexion regions having different flexions along a length from the proximal end to the distal end portion. A grasping configuration is provided at the distal end of the elongated core for retaining and capturing objects.
  • [0010]
    In yet another aspect, an intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tube member having a distal end portion. An elongated core member is disposed with the interior cavity of the tubular member for rotational or slidably movement within the tubular member and the elongated core member having a proximal end portion and a distal end portion. A grasping configuration is provided for capturing an object (e.g., clot or debris) therein in which the grasping configuration is formed by at least one movable jaw attached to the distal end portion of the elongated core member and a length portion of the distal end portion of the tube member.
  • [0011]
    In another aspect, an intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tubular member having a distal end portion. An elongated core member is disposed with the tubular member and the elongated core member has a proximal end portion and a distal end portion. A grasping configuration captures an object in which the grasping configuration includes unitarily formed plurality of movable jaws attached to the distal end portion of the elongated core member.
  • [0012]
    In another aspect, an intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tubular member has a distal end portion. An elongated core member being disposed with the tubular member and the elongated core member has a proximal end portion and a distal end portion. The device includes a grasping configuration for capturing an object therein, in which the grasping configuration is formed by a plurality of loop members attached to the distal end portion of the elongated core member.
  • [0013]
    In one aspect, an intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tubular member having a distal end portion. An elongated core member being disposed with the tubular member and the elongated core member having a proximal end portion and a distal end portion. A grasping configuration is provided for capturing an object therein, in which the grasping configuration is formed by at least one spiral member having a distal tip for penetrating an object to be removed from a human body lumen. In the device has the spiral member provided at the distal end portion of the elongated core member.
  • [0014]
    An intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tubular member having a distal end portion. An elongated core member is disposed with the tubular member and the elongated core member has a proximal end portion and a distal end portion. A grasping configuration captures an object therein, in which the grasping configuration is formed by at least one web member for retaining an object to be removed from a human body lumen, the web member being provided at the distal end portion of the elongated core member.
  • [0015]
    In various other aspects, at least one of the jaws may include an engaging surface and an opposing surface, the engaging surface including a plurality of engaging elements provided along a longitudinal length thereof and the engaging elements. In another aspect, wherein the engaging elements are provided as ribs inwardly extending for capturing an object. In another aspect, at least one of the jaws is perforated at the location of the ribs.
  • [0016]
    In another aspect, at least one of the jaws has a distal end with an aperture and the jaw includes a lumen along a length enabling a fluid communications pathway to a distal end of the jaw.
  • [0017]
    The above and other aspects, features and advantages of the present invention will be readily apparent and fully understood from the following detailed description illustrative embodiments in conjunction with the accompanying drawings, which are included by way of example, and not by way of limitation with regard to the claimed invention.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0018]
    FIG. 1 is a perspective view of schematic representation of an intracorporeal grasping system according to the teaching of present invention.
  • [0019]
    FIG. 2 is an elevational view of the grasping device shown in FIG. 1.
  • [0020]
    FIG. 3 is an enlarged section view of an elongated core member taken along the line 3-3 of FIG. 2.
  • [0021]
    FIG. 4 shows a side elevational view, partially in section, of the grasping device shown in FIG. 2 in a closed configuration within the inner lumen of the delivery catheter.
  • [0022]
    FIG. 5 depicts the grasping device disposed within the delivery catheter with the grasping assembly of the device extending out the port in the distal end of a delivery catheter into a body lumen adjacent to a thrombus and being in an expanded configuration therein.
  • [0023]
    FIG. 6 illustrates an elevational view of the grasping device within a delivery catheter having the grasping assembly on the distal end of the device being in a partially contracted configuration about a thromboembolism.
  • [0024]
    FIG. 7 is a schematic illustration of the grasping system shown in FIG. 1 operatively disposed in a left side internal carotid artery location in position to perform an exemplary thrombectomy procedure within the middle cerebral artery.
  • [0025]
    FIGS. 8A-8C illustrate an alternative embodiment of a grasping system according to the teaching of the present invention.
  • [0026]
    FIGS. 9A-9C illustrate an alternative embodiment of a grasping system according to the teaching of the present invention.
  • [0027]
    FIGS. 10A-10F illustrate an alternative embodiments of grasping device components according to the teaching of the present invention.
  • [0028]
    FIG. 11 illustrates an alternative embodiment of a grasping device component according to the teaching of the present invention.
  • [0029]
    FIGS. 12A-12E illustrate alternative embodiments of grasping device components according to the teaching of the present invention.
  • [0030]
    FIGS. 13A-13F illustrate another embodiment of a grasping system according to the teaching of the present invention.
  • [0031]
    FIGS. 14A-14D illustrate an alternative embodiment of a grasping system according to the teaching of the present invention.
  • [0032]
    FIGS. 15A-15B illustrate an alternative embodiment of a grasping system according to the teaching of the present invention.
  • [0033]
    FIGS. 16A-16C illustrate an alternative embodiment of a grasping device according to the teaching of the present invention.
  • [0034]
    FIGS. 17A-17D illustrate an alternative embodiment of a grasping device according to the teaching of the present invention. FIG. 17A is an elevational view of the grasping device; FIG. 17B is a front axial view of the grasping device; and FIG. 17C is a sectional view taken along line 17C-17C in FIG. 17A.
  • DETAILED DESCRIPTION
  • [0035]
    The following embodiments and aspects thereof are described and illustrated in systems and methods which are meant to exemplary and illustrative and non-limiting in scope.
  • [0036]
    FIGS. 1-6 schematically illustrate an intracorporeal grasping system 10. In one embodiment by way of example, the grasping system 10 includes a grasping device 11, a delivery catheter 12 and a guide catheter 13. In some instances only the grasping device 11 and either the delivery catheter 12 or the guide catheter 13 are used, but not both.
  • [0037]
    As shown in FIG. 1 and in greater detail in FIG. 2, the grasping device 11 includes an elongated core member 14 having a proximal end 15 and a distal end 16. The grasping device 11 further includes a grasping configuration 17 attached to the distal end of the core member 14. The core member 14 can have a number of arrangements. In one embodiment by way of example, core member 14 is provided with variable bending flexibility along a predetermined length. Hence, this configuration of the core member 14 allows for improved transluminal manipulation of the grasping device 11 in a human body. In one construction, core member 14 is flexible in nature so as to traverse the potentially tortuous and/or angled geometry of the cervical vascular tree.
  • [0038]
    With reference to FIG. 3, elongated core member 14 includes a cylindrical tube 25 having a generally uniform diameter. A generally solid cylindrical core wire 26 is concentrically disposed within the cylindrical tube 25. A circumferential gap between the tube 25 and wire 26 may be filled with solder, for example. The solid cylindrical core wire prevents uniform cylindrical tube 25 from excessive longitudinal elongating along its length.
  • [0039]
    In one embodiment by way of example, the flexibility of the uniform cylindrical tube 25 can be provided by a plurality of spaced circumferential slots 70 extending through the wall thickness (See FIG. 2). For ease of explanation, the term “density” with reference to cuts or slots of the core member, generally refers to the number of slots or cuts per a unit of length or area. Non limiting examples of a unit of length are a centimeter, an inch or smaller linear units. Likewise, a unit of area may be square inches or square centimeters and the like.
  • [0040]
    In accordance with an embodiment of the grasping device, the amount or magnitude of flexibility is proportional to the number of slots per unit of measure. For example, a high density of slots provides higher flexibility, than a lower density of slots. By changing the density and/or pattern of the circumferential slots, the flexibility of the elongated core member 14 can be changed.
  • [0041]
    Core member 14 may have a multi-flexion configuration that has separate regions of different flexions that each correspond to the flexibility, or lack thereof, for improved transluminal manipulation. This multi-flexion regional configuration provides adaptability for a practitioner to reduce steps for accessing or grasping an object or customize the access in body lumens to increase patient comfort. In one exemplary construction, the core member 14 may have three flex regions to accommodate to transluminal access. A first flexion region 29 may extend from the distal end 16 to a first intermediate position 29 a along the length of the elongated core member 14. The first flexion region 29 is substantially flexible for improved comfort, for example. An adjacent second flexion region 28 may extend to another intermediate position 28 a away from first intermediate position 29 a along the length of the elongated core member 14. The second flexion region 28 may be less flexible than a first flex region 29 so as to allow the elongated core member 14 to traverse the vascular geometry in an improved fashion. A third flex region 27 may be provided adjacent to the second flexion region 28. The third flexion region 27 may be less flexible than the second flexion region and the first flexion region.
  • [0042]
    Referencing FIG. 2, in one construction, the uniform diameter tube 25 has a distal section 29, middle section 28 and proximal section 27 generally corresponding to the multi-flexion configuration in which each section has a different flexibility with respect to each other. For example, the distal section 29 may have a high flexibility, the middle section 28 may have a medium flexibility, and the proximal section 27 has a low or minimal flexibility. Hence, distal section 29 has the greatest flexibility of the sections 28, 27. These sections are all part of the same uniform cylindrical tube 25 having three distinct stiffness or flexion sections. In one embodiment, the distal section 29 of the core member 14 can be at least in part 10%-25% more flexible than the proximal section 27 of the core member 14. The middle section 28 can be at least in part 5%-20% more flexible than the proximal section 27. The distal section 29 can be 5%-20% more flexible than the middle section 28. In alternative embodiment, the distal section 29 of the core member can be at least in part 35%-50% more flexible than the proximal section 27 of the core member. The middle section 28 can be at least in part 30%-45% more flexible than the proximal section 27. The distal section 29 can be 30%-45% more flexible than the middle section 28. Nevertheless, other flexibility relative values are possible.
  • [0043]
    Any suitable number of stiffness/flexible sections could be used on the core member 14. In a specific non-limiting example, the dimensions of the first flexion region maybe 3.0 cm from the distal end; second flexion region may have a length of 5.0 to 15.0 cm; and the third flexion region may have a length of 20.0 to 40.0 cm. Nevertheless, the length of the regions maybe configured as desired by the practitioner. In an alternative embodiment, the density of the slots can be increased uniformly for a continuous transition from proximal low flexibility to distal high flexibility for the core member 14.
  • [0044]
    The solid cylindrical core wire 26 spans the length of the uniform cylindrical tube 25 and is affixed to the tube by any suitable method by soldering e.g. with silver or gold solder. brazing, welding, adhesives, mechanical connections or other suitable techniques. The solid cylindrical core wire 26 is preferably attached to the tube at least at both ends of the core wire.
  • [0045]
    The circumferential slots or cuts can be made by any suitable manufacturing technique, such as, for example, computer numerically controlled (CNC) microsawing, EDM wire cutting, or laser cutting.
  • [0046]
    The uniform cylindrical tube 25 is generally formed of a high strength material such as stainless steel, superelastic nickel-titanium alloy, cobalt-chromium-molybdenum alloys such as MP35N and Elgiloy or other material having suitable strength, stiffness, and other attributes for allowing percutaneous transluminal manipulation of the grasping device 11 as described herein. Suitable materials include but are not limited to 304SS or NITINOL.
  • [0047]
    As used herein, the term “superelastic shape memory material” refers to a class of metal alloys that have a stress-induced phase change from austenite to martensite and upon stress release, the material springs back to this original phase and shape. The material structure of a superelastic shape memory material regarding austenite and martensite is well-known to one of ordinary skill in the metallurgy art. A NiTi material or NiTi alloy may be used as an alloy material for the flex control member 21. As used herein, a NiTi superelastic shape memory material refers to an alloy that is an intermetallic compound of nickel and titanium having nearly equal mixtures as measured by weight. One composition of a NiTi superelastic shape memory material generally has a greater percentage of nickel by weight than titanium, such as 51%-56% of nickel, and preferably 54-55% nickel. The specific percentages of nickel and titanium can be adjusted by one of ordinary skill in the art. It should be recognized that additional metals, such as copper, iron, chromium, and cobalt, can be added to fine tune various properties of a NiTi superelastic shape set material.
  • [0048]
    One embodiment, core member 14 is preferably constructed from a superelastic shape set material commonly called NITINOL® depending upon the alloy composition. NITINOL® is a brand name which refers to Nickel Titanium Naval Ordinance Laboratory, a commercially available family of nickel titanium alloys. Among the suppliers, NITINOL® material can be obtained from NDC of Fremont, Calif. Nevertheless, there are numerous other suppliers of NiTi materials and NiTi superelastic shape set materials.
  • [0049]
    The outer diameter of cylindrical tube 25 should be selected for slidable advancement within the inner lumen 36 of the delivery catheter (See FIGS. 1 and 4). Generally, outer diameter of cylindrical tube 25 is about 0.015 inch to about 0.040 inch, and preferably about 0.010 to about 0.038 inch. An outer lubricous coating (not shown) may be provided on the exterior of the cylindrical tube 25 at least along distal portion 27. Suitable coatings include fluoropolymers such as polytetrafluoroethylene (TEFLON) or hydrophilic materials.
  • [0050]
    The inner diameter of cylindrical tube 25 is provided in suitable diameter to enclose solid cylindrical core wire 26 therein. Generally, inner diameter of cylindrical tube 25 is about 0.005 inch to about 0.036 inch. A typical dimension of uniform cylindrical tube 25 is 0.016″OD×0.009″ID. Nevertheless, other dimensions may be used.
  • [0051]
    The grasping assembly 17 may be any suitable grasping assembly. As depicted in FIGS. 1 and 2, the grasping assembly 17 has a plurality of arms 20 disposed about the longitudinal axis 21 of the device 11 with proximal arm sections 22 secured to the distal end 16 of the core member 14 and distal arm sections 23 which extend essentially parallel to the longitudinal axis 21 e.g. not more than 5° from a line parallel to longitudinal axis when the grasping assembly 17 is in an expanded configuration as shown. The distal arm sections 23 have inwardly extending, object engaging elements 24 at their distal ends. The bluntness of the object engaging element 17 provides a non-traumatic feature to the distal end of the arms 20. The proximal portion 25 of the grasping device 11 is usually of uniform outer diameter and is of sufficient length so that the proximal end 15 extends out of the delivery catheter 12 when the grasping assembly 17 extends out the distal end of the delivery catheter.
  • [0052]
    As shown in FIG. 1 the delivery catheter 12 has a tubular body 30 with an adapter 31 on the proximal end 32, a port 33 in the adapter 31, a distal end 34, a port 35 in the distal end and an inner lumen 36 extending between and in fluid communication with proximal port 33 in the adapter 31 and the distal port 35. A radiopaque marker 37 is provided on the distal end 34 to facilitate fluoroscopic observation of the distal end of the delivery catheter 12 during a procedure within a patient's body, such as a thrombectomy. The inner lumen 36 is configured to slidably receive the grasping device 11 with the grasping assembly 17 in the contracted configuration as shown in FIG. 4. The adapter 31 is preferably provided with a hemostatic valve (not shown).
  • [0053]
    Delivery catheter 12 is generally constructed to track over a conventional guidewire beyond the guide catheter 13 in the cervical anatomy and into the cerebral vessels associated with the brain and may also be chosen according to several standard, “microcatheter” designs that are generally available. Accordingly, delivery catheter 12 has a length that is at least 125 cm long, and more particularly may be between about 125 cm and about 175 cm long. Typically, the delivery catheter 12 is about 155 cm long. The inner lumen 36 of the delivery catheter generally has an inner diameter between about 0.01 inch and about 0.08 inch (0.25-2.03 mm). Commercially available microcatheters are generally suitable for use as delivery catheters.
  • [0054]
    Also shown in FIG. 1 is guide catheter 13 has a tubular body 40, a proximal end 41, a distal end 42, and an inner lumen 43 extending between a proximal port 44 in the proximal end and a distal port 45 in the distal end of the guide catheter. The proximal end 41 of guide catheter 13 may be provided with an adapter (not shown) having a hemostatic valve. Guide catheter 13 is generally constructed to bridge between a femoral artery access site and a cervical region of the carotid or vertebral artery and may be chosen according to several standard designs that are generally available.
  • [0055]
    Accordingly, guide catheter 13 is generally at least 85 cm long, and more particularly may be between about 95 cm and about 105 cm long. Further to conventional and available designs, the inner lumen 43 of guide catheter 13 generally has an inner diameter that is between about 0.038 inch and 0.090 inch (0.88-2.29 mm), and more particularly may be between about 0.052 inch and about 0.065 inch (1.32-1.65 mm).
  • [0056]
    Grasping device 11 is configured to slidably fit within the inner lumen 36 of delivery catheter 12. For procedures involving distal locations of thromboembolic neurovascular occlusions, the grasping device 11 is configured to be delivered through the inner lumen 36 of the delivery catheter 12 with a diameter that is equal to or less than about 0.042 inches (1.07 mm), preferably less than about 0.022 inches (0.559 mm). In the case of use in a more distal, tortuous, and smaller vessel anatomy, configuration for delivery through a delivery catheter inner lumen less than 0.018 inch (0.457 mm) diameter may be used. For most neurovascular occlusions, the grasping device 11 is about 135 cm to about 300 cm long, and more particularly may be about 150 cm to about 200 cm long. Generally, the grasping device 11 is about 175 cm long and is adapted to be used in a delivery catheter 12 that is about 150 cm long. Nevertheless, other values for diameters and lengths are possible.
  • [0057]
    The device as described does not include a tapered core mandrel as disclosed in U.S. Pat. No. 6,679,893. Instead, the grasping elements are attached to the distal end of a generally uniform cylindrical tube in one embodiment.
  • [0058]
    Grasping assembly 17 is adjustable between different configurations, namely, a completely contracted configuration or nearly contracted configuration as generally shown in FIG. 4 to facilitate disposition within the inner lumen 36 of delivery catheter 12. In another arrangement grasping assembly has a completely expanded configuration or nearly expanded configuration as generally shown in FIGS. 1, 2 and to facilitate advancement of the expanded grasping assembly 17 within the body lumen about the object to be captured. In yet another arrangement, assembly 17 has a partially contracted configuration to hold onto or capture the object as generally shown in FIG. 7. Grasping assembly 17 is shown in FIGS. 1, 2 and 5 in the expanded configuration which is generally defined by each of the arms 20 in a completely expanded position and the distal arm sections 23 being generally parallel or nearly parallel to longitudinal axis 21, which in a preferred embodiment is the relaxed memory state for the arms 20.
  • [0059]
    Grasping assembly 17 is adjustable from the expanded configuration as generally shown in FIG. 5 to the contracted or partially contracted configuration by the application of force against the inclined proximal arm sections 22 by advancing the distal end 35 of the delivery catheter 12 as shown by the arrow 38 in FIG. 6 against the inclined proximal arm sections.
  • [0060]
    Arms 20 may be constructed of various materials having suitable strength, elasticity and memory for use in engaging and removing an object such as thrombus from a body lumen, particularly a cerebral vessel. However, arms 20 are generally constructed from a metal which may be for example platinum (or alloys thereof), stainless steel, superelastic shape memory material, or high strength cobalt-chromium-molybdenum alloys. Platinum or alloys thereof are preferred because they provide a particular beneficial combination of a non-traumatic distal tip for the arms 20 and radiopacity for fluoroscopic observation of the arms in an intracorporeal procedure.
  • [0061]
    There are any number of alternative arrangement for practicing techniques and aspects of the grasping device 11. More specific features of the use of the device and system in capturing and removing, for example, thromboembolic occlusions from the distal cerebral vessels are described in the foregoing. Nevertheless, the inventive aspects of the grasping device 11 can be used for any number of alternative arrangements. Hence, the following example is illustrative of a method of using the grasping device 11.
  • [0062]
    First, an access site is prepared as either a puncture wound (i.e. Seldinger technique) or as a surgical cut-down, typically in the femoral artery although in rare circumstances vascular access may be made at other peripheral vessels such as a brachial artery. An introducer (not shown) may be used to provide hemostatic access at the access site via an incorporated hemostatic valve. Guide catheter 13 is than advanced through the introducer until distal end 42 is positioned with distal port 45 at a region of a cervical vessel 50, thereby providing transluminal access to the cervical vascular tree as shown in FIG. 7. Delivery catheter 12 is advanced through the inner lumen 43 of guide catheter 13 and out the distal port 45 thereof until the distal end 34 of the delivery catheter is positioned adjacent to the thromboembolism 50 located in the middle cerebral artery 51.
  • [0063]
    In the case where the distal location of the thromboembolism is beyond a bifurcated vessel or otherwise tortuous cerebral vessels, the delivery catheter 12 may be advanced over a conventional guide wire (not shown). Once the delivery catheter 12 is positioned adjacent to the thromboembolism 50, the guide wire is removed from the patient and is then replaced with grasping device 11. Grasping device 11 is advanced through the inner lumen 36 of the delivery catheter in the contracted configuration as shown in FIG. 5, until it exits through distal port 35 into the blood vessel 51 where the grasping assembly 17 self-adjusts to the expanded configuration with arms 20 in a radially expanded position. Grasping assembly 17 is then advanced, as indicated by the arrow 52, in the expanded configuration distally so that arms 20 advance around the thromboembolism 50 as shown in FIG. 5. Then, delivery catheter 12 is advanced distally to press against proximal arm sections 22 to force distal arm sections 23 to rotate radially inwardly to a partially contracted configuration so that the object engaging members 24 engage the thromboembolism 50 as shown in FIG. 7. Thereafter, the grasping device 11, delivery catheter 12, and thromboembolism 50 may be removed from the location and further from the body, either through guide catheter 13 or together in combination with guide catheter.
  • [0064]
    FIGS. 8A-8C schematically illustrate an alternative intracorporeal grasping system 610. Intracorporeal grasping system 610 includes at least one jaw 70 and a scoop 71 used to extract the object to be captured between the jaw 70 and scoop 71. The scoop may be a rigid member 72 that extends from tube 30 as shown in FIG. 8A, or a catheter scoop 73 formed by cutting away the tip of tube 30 to form a scoop as shown in FIG. 8B and FIG. 8C. A single jaw is depicted in these figures; however, more than one jaw may be used. The cutting operation to form the scoop 73 can be a suitable method such as laser cutting.
  • [0065]
    The jaw 70 is generally disposed along the longitudinal axis 74 and has a proximal arm section 75 secured to the distal end 16 of the elongate core member 14. The proximal arm section 75 is inclined from the distal end 16 of the elongate core member 14. The inclined proximal arm section 75 functions to aid in placing the jaw 70 of the grasping assembly 17 into a contracted or partially contracted configuration about the longitudinal axis 74 by the force applied to the inclined section by advancement of the distal end of the delivery catheter 12 and has a length selected to provide the desired radial spacing between the distal arm section 76 and the scoop 71. An inwardly extending object engaging element 77 is disposed at the distal end of jaw 70. The jaw 70 typically extends beyond the length of the scoop as shown in FIG. 8A.
  • [0066]
    In one operation, the scoop 71 is forced, wedged, or placed under the object to be captured. The jaw 70 extends beyond the length of the scoop and is retracted by moving the elongate core member 14 inward distally. As the jaw 70 is being retracted, it is forced to bite down on the object towards the longitudinal axis 74. When jaw 70 engages the object it then pulls the object along the length of the scoop 71 into tubular body 30 for removal.
  • [0067]
    Jaw 70 may be constructed from a flat ribbon or wire. Jaw 70 may be constructed of various materials having suitable strength, elasticity and memory for use in engaging and removing an object such as thrombus from a body lumen, particularly a cerebral vessel. In one embodiment, jaw 70 may be generally constructed from a metal which may be for example platinum (or alloys thereof), stainless steel, super-elastic nickel-titanium alloy, or high strength cobalt-chromium-molybdenum alloys.
  • [0068]
    Rigid member 72 may be constructed of various materials having suitable strength and is generally constructed from a metal which may be for example platinum (or alloys thereof), stainless steel, super-elastic nickel-titanium alloy, or high strength cobalt-chromium-molybdenum alloys.
  • [0069]
    FIGS. 9A-9C schematically illustrate an alternative intracorporeal grasping system 210. A grasping configuration 217 is provided for capturing an object (e.g., clot or debris) therein, in which the grasping configuration comprises unitarily formed plurality of movable jaws 90 attached to the distal end portion of the elongated core member 214. It is noted that core member 214 can have the construction of core member 14 as well as other constructions.
  • [0070]
    In another embodiment, jaws 90 are formed from thin tubing 96 which is cut, e.g. with a laser, to form narrow jaws 90. (See FIG. 9A). Each jaw 90 has a proximal arm section 91 extending from tubing 96. As shown in FIG. 9B, the proximal arm section 91 is inclined from the tubing 96. The inclined proximal arm section 92 functions to aid in placing the jaws 90 of the grasping configuration 217 into a contracted or partially contracted configuration about the longitudinal axis 94 by the force applied to the inclined section by advancement of the distal end of the delivery catheter 12 (FIGS. 1-2) and has a length selected to provide the desired radial spacing between the distal arm sections 92. Inwardly extending object engaging elements 93 are disposed at the distal end of jaws 90.
  • [0071]
    Tube 96 is disposed onto the distal end of the elongate core member 214, as shown in FIG. 9B and adhered into place or fastened or otherwise attached thereto. In operation, the jaws 90 extend along a length of the object to be removed and are retracted by retracting elongate core member 14. As the jaws are being retracted, they are forced to bite down on the object and then pull the object into tubular body 30.
  • [0072]
    As with various jaws disclosed herein, jaws 90 may be constructed of various materials having suitable strength, elasticity and memory for use in engaging and removing an object such as thrombus from a body lumen, particularly a cerebral vessel. However, jaws 90 are generally constructed from a metal which may be for example platinum (or alloys thereof), stainless steel, super-elastic nickel-titanium alloy, or high strength cobalt-chromium-molybdenum alloys.
  • [0073]
    It is noted that jaw assemblies generally have an inwardly extending object engaging elements disposed at the distal end of jaws. This is shown in the embodiments of FIGS. 8-9 above, for example. In further embodiments, the jaws may contain engaging elements. The jaws may be suitable jaws as any embodiments described herein. FIGS. 10A-10F illustrates alternative arrangement of jaws with various engaging elements for removing a thrombus, for example.
  • [0074]
    Engaging elements allow the jaw to grip the object to be removed. In addition to engaging elements 24 in FIG. 10A, a plurality of engaging elements can be applied to arm segment 22 and/or arm segment 23 (e.g., FIGS. 1-4). The engaging elements 101 extend towards the object to be removed and may be applied as a separate member for the arm segments, such as by soldering as shown in FIG. 10A. Alternatively, the engaging elements may be formed by cutting tabs 102 in the arm segments and bending inward as shown in FIG. 10B, or by pressing grooves or ribs 103 onto the inside surface of the ribbon forming a jaw as shown in FIG. 10C.
  • [0075]
    In one arrangement, the arm segment 23 with engaging elements may include a distal blunt edge 105 as shown in FIG. 10D or arm segment 23′ with a distal sharp edge or distal “bladed” edge 107 as shown in FIGS. 10E-F. A distal blunt edge 105 is useful for grabbing the debris and pulling into the tubular member 30. As shown in FIG. 10D, the distal portion can be angled inward more than 90 degrees from the horizontal as denoted by angle “A”. For example, the angle may be 91-97 degrees or 93-95 degrees. Additionally, the distal sharp edge 107 is useful for grabbing the debris and pulling into the tubular member 13, but also useful for cutting or biting off chunks of the debris (clot), for example, if the debris is too large to remove in as a single unit.
  • [0076]
    As shown in FIG. 1, jaws can be formed of a unitary piece of ribbon or wire, such as platinum ribbon or wire, which is bent into a U or V shape. Nevertheless, other shapes are possible. The two edges of the ribbon or wire form two jaws which include two arm segments 22, 23 and two engaging elements 24. The ribbon or wire is attached to elongate core member 14 such as via coil 19.
  • [0077]
    FIGS. 12A-12E schematically illustrate an alternative embodiment for a grasping assembly component. As shown in FIGS. 12A-12E, the jaws 300 may be formed from tubing having a desired cross-section, such as a circular 301, rectangular 303, triangular 305, oval 310 or other shape to provide benefits of grasping objects in a human body or surgical benefits. The hollow interior of the tube forms a lumen 307 which can be used to inject or deliver fluidic substances or medicament to the object to be removed at the distal end 309. In one embodiment, the distal end 309 of the jaws 300 has an aperture for delivering fluids. In one example, a substance might be injected though the jaws 300 in order to soften the object to be removed. Nevertheless, different type of substances can be provided. Alternatively, a vacuum may be applied to the tube to remove fluids or to provide a negative pressure region at the distal end 309 of the jaws 300 to remove portions of the object designated for removal or other debris.
  • [0078]
    FIGS. 13A-13E illustrate an alternative intracorporeal grasping system 400. At least one jaw member collectively defines a loop configuration 405 to advantageously increase the coverage/grasping area of the objects to be grabbed and removed from the human body. Further, the loops retains the object specifically between the contact other loops. Hence, the grasping element 17 can be formed from a plurality of loops 405 (such as two loops) which engaged each to capture or clamp objects therein.
  • [0079]
    While the loop configuration is preferably a circle, it could be in the form of a myriad of different closed loops including without limitation ovals, squares and irregular shapes. Nevertheless, other shapes can be used. The loop should simply define a substantially closed configuration to retain the object therein. The loops can be of different shapes and forms and various cross-sections as is suitable for the particular type and shape of object to be removed. For example the loops may have a spatula shape as shown in FIG. 13A or a spoon shape as shown in FIG. 13B.
  • [0080]
    The loops are attached to the elongate core member 14 such as a core wire or, as shown in FIG. 13D, coil 19. The outer tubular member 30 moves forward to bring the loops together and apart as shown in FIG. 13C. The grasping assembly can also combine loops with jaws as shown in FIG. 13C. The loop would encircle a larger surface area of the object to be removed whereas the jaws would clamp onto the object to be removed. The arrangement of loops and jaws provides an increase of total surface area than jaws alone, but allows the object to be grabbed into and held. It should be noted that the embodiment of FIGS. 13A-D may be constructed with tubing having a wall with perforations for releasing a fluid within the tubing as disclosed in the embodiments of FIGS. 12A-12E.
  • [0081]
    Loops 405 may be formed from ribbon or wire. Loops 405 may be constructed of various materials having suitable strength, elasticity and memory for use in engaging and removing an object such as thrombus from a body lumen, particularly a cerebral vessel. However, loops are generally constructed from a metal which may be for example platinum (or alloys thereof), stainless steel, super-elastic nickel-titanium alloy, or high strength cobalt-chromium-molybdenum alloys.
  • [0082]
    FIGS. 14A-14D illustrate an alternative intracorporeal grasping system 500. A grasping assembly 501 may be formed in a web configuration such with webbed jaws. Webbed jaws provide stronger and increased coverage or encapsulation of the object to be removed than jaws without webs. The web may be constructed by attaching fiber or welding metallic strands to the individual grasping mechanism.
  • [0083]
    The webs may be formed from ribbon as shown in FIGS. 14A-14C or wire as shown in FIG. 14D. The webs connect between jaws in a concave or convex manner as shown in FIG. 14B or 14C as are flexible to bend or stretch based on the movement of elongate member 14 into and out of tube 30.
  • [0084]
    Webs 110 can be attached during jaw formation, or they can be formed from the same piece of the jaws. The jaws can be made in a manner similar to a laser cut stent, so webs and jaws are one piece (cut tubing). Webs 110 may be constructed of various materials having suitable strength, elasticity and memory for use in engaging and removing an object such as thrombus from a body lumen, particularly a cerebral vessel. However, loops are generally constructed from a metal which may be for example platinum (or alloys thereof), stainless steel, super-elastic nickel-titanium alloy, or high strength cobalt-chromium-molybdenum alloys.
  • [0085]
    FIGS. 15A-15B illustrate an alternative intracorporeal grasping system 100. The proximal arm sections and distal arm sections may have different lengths and can be offset for different specific intended procedures. As shown in FIG. 15A, opposing pairs of jaws 111 comprising proximal arm 115 section and distal arm section 116 having a longer longitudinal length (as measured from the distal end 16 of core member 14) than the longitudinal length opposing pairs of jaws 112 comprising proximal arm 117 section and distal arm section 118. Hence, the jaws 111 and 112 are offset from each other a longitudinal distance denoted as “delta X” or simply “X”. The jaws 111 and 112 are offset from each other such that when tube 30 slidably engages the periphery of the jaws, the longer jaws 111 will contract before the shorter jaws 112. The offsetting feature of the jaws enables the jaws 111, 112 to clamp down at different times during longitudinal movement of the lumen 30 towards to the jaws 111, 112. Each jaw may be offset relative to the other jaws or pairs of jaws may be offset relative to other pairs of jaws. Nevertheless, other configurations are possible for the grasping system 100.
  • [0086]
    FIGS. 16A-16C illustrate an alternative intracorporeal grasping system. Elongate core member 14 comprises an elongate tube 120 positioned within tube 30. Jaws 121 are attached to or formed at the distal end of elongate tube 120 as shown in FIG. 16A such that when core member 14 is withdrawn into tube 30, the jaws clamp down on an object to be removed. Referring to FIG. 16C, the elongated tube 120 may have a multi-flexion configuration that has separate regions of different flexions that each correspond to the flexibility, or lack thereof, for improved transluminal manipulation. This multi-flexion regional configuration provides adaptability for a practitioner to reduce steps for accessing or grasping an object or customize the access in body lumens to increase patient comfort. This feature incorporates the features of grasping system 10 as discussed in the foregoing.
  • [0087]
    Generally concentrically located within elongate tube 120 is elongate cylindrical member 123 having a spiral-shaped member 122 (e.g., corkscrew-like member) attached to a distal end thereof. The elongate cylindrical tube 120 may be tapered in one embodiment. The member 123 may have various dimensional characteristics. In one example, the outer diameter (“OD”) at the distal end of the cylindrical member 123 may be 0.012 inches. The spiral-shaped member 122 may be formed with a wire having an OD about may be 0.008 inches to 0.010 inches. Nevertheless, other configurations and dimensions are possible within the scope of the invention. The spiral shaped member 122 may be formed integrally with the distal end of the cylindrical member 123.
  • [0088]
    The spiral-shaped member 122 engages into an object to be removed (e.g., clot 50) via rotational movement about a longitudinal axis 125. The distal end 127 of the spiral-shaped member 122 includes sharpen tip for penetrating into the interior of the clot during the rotational movement. Once the clot is engaged by member 122, then the elongate tube 120 is withdrawn into tube 30. Elongate tube 120 is preferably flexible. The jaws 121 may be attached to the inside or outside of the tube 120 or may be formed from the tube itself as disclosed in alternative embodiment herein (e.g., FIGS. 8A-8C, and 9A-9C). Nevertheless, other configurations and arrangements are possible.
  • [0089]
    FIGS. 17A-17D illustrate an alternative embodiment of a grasping device according to the teaching of the present invention. Jaws 20 are made of wire having a generally circular cross-section. It was discovered that the circular cross-section of the jaws allows the jaws to be easily inserted and aligned evenly in coil 19 (See FIG. 17A) or other concentric tube or guidewire. The jaws are more flexible than conventional jaws, which allow a better grip on the object to be removed.
  • [0090]
    At least six, preferably eight to twelve, wire jaws 20 are integrally secured to the distal end 16 of the elongate core member 14 and disposed about the longitudinal axis 21. Outer tubular body 30 (see FIG. 1) surrounds the jaws 20 and coil 19.
  • [0091]
    Each jaw 20 has a proximal arm section 22 secured to the distal end 16 of the elongate core member 14. The proximal arm section 22 is inclined from the distal end 16 of the core member 14. The inclined proximal arm section 22 functions to aid in placing the jaws 20 of the grasping assembly 17 into a contracted or partially contracted configuration about the longitudinal axis 21 by the force applied to the inclined section by advancement of the distal end of the delivery catheter 12 and has a length selected to provide the desired radial spacing between the distal arm sections 23.
  • [0092]
    In operation, the jaws 20 extend along a length of the object to be removed and are retracted by retracting elongate core member 14. As the jaws are being retracted, they are forced to bite down on the object and then pull the object into tubular body 30.
  • [0093]
    Jaws 20 may be constructed of various materials having suitable strength, elasticity and memory for use in engaging and removing an object such as thrombus from a body lumen, particularly a cerebral vessel. However, jaws 20 are generally constructed from a metal which may be for example platinum (or alloys thereof), stainless steel, super-elastic nickel-titanium alloy, or high strength cobalt-chromium-molybdenum alloys.
  • [0094]
    While the arrangements and various embodiments described are believed to be well suited for engaging and removing various objects from various body spaces, the primary basis underlying many of the beneficial features herein described are for the purpose of accessing distal, tortuous cerebral vessels for removal of thromboembolism in the treatment of strokes, as previously described above. Nevertheless, other purposes of devices can be advantageously applied to other biological organisms.
  • [0095]
    There are any number of alternative arrangement for practicing techniques and aspects herein. For example, an intracorporeal grasping device may include a tubular member for entering a lumen of a human body and the tube member having a distal end portion. An elongated core member is disposed with the interior cavity of the tubular member for rotational or slidably movement within the tubular member and the elongated core member having a proximal end portion and a distal end portion. A grasping configuration is provided for capturing an object (e.g., clot or debris) therein in which the grasping configuration is formed by at least one movable jaw attached to the distal end portion of the elongated core member and a length portion of the distal end portion of the tube member. The grasping configuration may include unitarily formed plurality of movable jaws attached to the distal end portion of the elongated core member. Further, the grasping configuration may be formed by a plurality of loop members attached to the distal end portion of the elongated core member.
  • [0096]
    In another example, an intracorporeal grasping device includes a tubular member for entering a lumen of a human body and the tubular member having a distal end portion. An elongated core member being disposed with the tubular member and the elongated core member having a proximal end portion and a distal end portion. A grasping configuration is provided for capturing an object therein, in which the grasping configuration is formed by at least one spiral member having a distal tip for penetrating an object to be removed from a human body lumen. The device has the spiral member provided at the distal end portion of the elongated core member. The grasping configuration can be formed by at least one web member for retaining an object to be removed from a human body lumen, the web member being provided at the distal end portion of the elongated core member.
  • [0097]
    There are any number of alternative combinations for defining the invention, which incorporate one or more elements from the specification, including the description, and drawings and claims, in various combinations or sub combinations. It will be apparent to those skilled in the relevant technology, in light of the present specification, that alternate combinations of aspects of the invention, either alone or in combination with one or more elements or steps defined herein, may be utilized as modifications or alterations of the invention or as part of the invention. It may be intended that the written description of the invention contained herein covers all such modifications and alterations.
Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US4198960 *Jan 31, 1978Apr 22, 1980Olympus Optical Co., Ltd.Apparatus for removing a foreign matter having individually operable trapping and flexing wires, a central channel for illumination, suction and injection and a laterally disposed bore for feeding fluids
US4650466 *Nov 1, 1985Mar 17, 1987Angiobrade PartnersAngioplasty device
US4655771 *Apr 11, 1983Apr 7, 1987Shepherd Patents S.A.Prosthesis comprising an expansible or contractile tubular body
US4727873 *Nov 26, 1986Mar 1, 1988Mobin Uddin KaziEmbolus trap
US4733665 *Nov 7, 1985Mar 29, 1988Expandable Grafts PartnershipExpandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4739762 *Nov 3, 1986Apr 26, 1988Expandable Grafts PartnershipExpandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4807626 *Dec 30, 1985Feb 28, 1989Mcgirr Douglas BStone extractor and method
US4890611 *Apr 5, 1988Jan 2, 1990Thomas J. FogartyEndarterectomy apparatus and method
US4909789 *Mar 24, 1987Mar 20, 1990Olympus Optical Co., Ltd.Observation assisting forceps
US5100423 *Aug 21, 1990Mar 31, 1992Medical Engineering & Development Institute, Inc.Ablation catheter
US5102417 *Mar 28, 1988Apr 7, 1992Expandable Grafts PartnershipExpandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US5190058 *May 22, 1991Mar 2, 1993Medtronic, Inc.Method of using a temporary stent catheter
US5192286 *Jul 26, 1991Mar 9, 1993Regents Of The University Of CaliforniaMethod and device for retrieving materials from body lumens
US5195984 *Feb 19, 1991Mar 23, 1993Expandable Grafts PartnershipExpandable intraluminal graft
US5197978 *Apr 26, 1991Mar 30, 1993Advanced Coronary Technology, Inc.Removable heat-recoverable tissue supporting device
US5211636 *Oct 31, 1990May 18, 1993Lake Region Manufacturing Co., Inc.Steerable infusion guide wire
US5297310 *Jan 21, 1993Mar 29, 1994Dennis CoxCleaning brush for endoscopes
US5300086 *Dec 2, 1992Apr 5, 1994Pierre GoryDevice with a locating member for removably implanting a blood filter in a vein of the human body
US5387219 *Dec 30, 1993Feb 7, 1995Target TherapeuticsMedical retrieval snare with coil wrapped loop
US5407807 *Apr 23, 1993Apr 18, 1995Daymark Medical Industries, Inc.Method and apparatus for detecting sepsis causation in a catheter
US5411549 *Jul 13, 1993May 2, 1995Scimed Life Systems, Inc.Selectively expandable, retractable and removable stent
US5490859 *Apr 29, 1993Feb 13, 1996Scimed Life Systems, Inc.Expandable intravascular occlusion material removal devices and methods of use
US5496330 *Jun 10, 1994Mar 5, 1996Boston Scientific CorporationSurgical extractor with closely angularly spaced individual filaments
US5501694 *Mar 3, 1994Mar 26, 1996Scimed Life Systems, Inc.Expandable intravascular occlusion material removal devices and methods of use
US5709704 *Nov 30, 1994Jan 20, 1998Boston Scientific CorporationBlood clot filtering
US5720764 *Jun 10, 1995Feb 24, 1998Naderlinger; EduardVena cava thrombus filter
US5749883 *Aug 26, 1996May 12, 1998Halpern; David MarcosMedical instrument
US5882329 *Feb 12, 1997Mar 16, 1999Prolifix Medical, Inc.Apparatus and method for removing stenotic material from stents
US5895398 *Oct 2, 1996Apr 20, 1999The Regents Of The University Of CaliforniaMethod of using a clot capture coil
US5895400 *Jun 27, 1997Apr 20, 1999Abela; George S.Catheter with bristles
US5897567 *Sep 9, 1997Apr 27, 1999Scimed Life Systems, Inc.Expandable intravascular occlusion material removal devices and methods of use
US5902263 *Dec 24, 1997May 11, 1999Prolifix Medical, Inc.Apparatus and method for removing stenotic material from stents
US5904698 *Jun 10, 1997May 18, 1999Applied Medical Resources CorporationSurgical shaving device for use within body conduits
US6013086 *Jul 31, 1998Jan 11, 2000Asahi Kogaku Kogyo Kabushiki KaishaWire loop type instrument for endoscope
US6013093 *Nov 28, 1995Jan 11, 2000Boston Scientific CorporationBlood clot filtering
US6022363 *Dec 21, 1998Feb 8, 2000Micro Therapeutics, Inc.Rotatable dynamic seal and guide for a medical obstruction treatment device sub-assembly coupled to a drive motor unit
US6027520 *Apr 5, 1999Feb 22, 2000Embol-X, Inc.Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US6030397 *Dec 21, 1998Feb 29, 2000Micro Therapeutics, Inc.Miniaturized medical brush
US6063100 *Feb 22, 1999May 16, 2000Cordis CorporationEmbolic coil deployment system with improved embolic coil
US6168603 *Nov 6, 1997Jan 2, 2001Boston Scientific CorporationSurgical extractor
US6168604 *Sep 21, 1999Jan 2, 2001Metamorphic Surgical Devices, LlcGuide wire device for removing solid objects from body canals
US6171327 *Feb 24, 1999Jan 9, 2001Scimed Life Systems, Inc.Intravascular filter and method
US6174318 *Apr 23, 1998Jan 16, 2001Scimed Life Systems, Inc.Basket with one or more moveable legs
US6179857 *Feb 22, 1999Jan 30, 2001Cordis CorporationStretch resistant embolic coil with variable stiffness
US6179859 *Jul 16, 1999Jan 30, 2001Baff LlcEmboli filtration system and methods of use
US6187017 *Feb 17, 1998Feb 13, 2001Circon CorporationRetrieval basket for a surgical device
US6190394 *Nov 5, 1999Feb 20, 2001Annex Medical, Inc.Medical retrieval basket
US6193745 *Jun 4, 1997Feb 27, 2001Medtronic, Inc.Modular intraluminal prosteheses construction and methods
US6203552 *Mar 19, 1999Mar 20, 2001Cook Urological IncorporatedMinimally invasive medical retrieval device
US6214025 *Oct 27, 1999Apr 10, 2001Boston Scientific CorporationSelf-centering, self-expanding and retrievable vena cava filter
US6221039 *Oct 26, 1998Apr 24, 2001Scimed Life Systems, Inc.Multi-function surgical instrument
US6336934 *Nov 9, 1998Jan 8, 2002Salviac LimitedEmbolic protection device
US6361558 *May 9, 2000Mar 26, 2002Cordis Neurovascular, Inc.Stent aneurysm treatment system and method
US6379329 *Jun 1, 2000Apr 30, 2002Cordis Neurovascular, Inc.Detachable balloon embolization device and method
US6511468 *Aug 31, 1999Jan 28, 2003Micro Therapeutics, Inc.Device and method for controlling injection of liquid embolic composition
US6514191 *Jan 25, 2000Feb 4, 2003Schneider (Europe) A.G.Medical appliances for the treatment of blood vessels by means of ionizing radiation
US6514273 *Mar 22, 2000Feb 4, 2003Endovascular Technologies, Inc.Device for removal of thrombus through physiological adhesion
US6520968 *Aug 3, 2001Feb 18, 2003Scimed Life SystemsReleasable basket
US6530935 *Oct 12, 1998Mar 11, 2003Regents Of The University Of California, TheClot capture coil and method of using the same
US6533811 *May 9, 1997Mar 18, 2003Medtronic, Inc.Internal graft prosthesis and delivery system
US6554849 *Sep 11, 2000Apr 29, 2003Cordis CorporationIntravascular embolization device
US6673106 *Jun 5, 2002Jan 6, 2004Cordis Neurovascular, Inc.Intravascular stent device
US6679893 *Nov 16, 2000Jan 20, 2004Chestnut Medical Technologies, Inc.Grasping device and method of use
US6685722 *Nov 10, 1999Feb 3, 2004Microvention, Inc.Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
US6692508 *Sep 3, 2002Feb 17, 2004The Regents Of The University Of CaliforniaMethod of using a clot capture coil
US6692509 *Sep 3, 2002Feb 17, 2004Regents Of The University Of CaliforniaMethod of using a clot capture coil
US6702830 *Jun 9, 2000Mar 9, 2004Bacchus Vascular, Inc.Mechanical pump for removal of fragmented matter and methods of manufacture and use
US6723108 *Sep 18, 2000Apr 20, 2004Cordis Neurovascular, IncFoam matrix embolization device
US6878151 *Sep 27, 2001Apr 12, 2005Scimed Life Systems, Inc.Medical retrieval device
US6989020 *Sep 23, 2002Jan 24, 2006Cordis Neurovascular, Inc.Embolic coil retrieval system
US7001422 *Feb 12, 2003Feb 21, 2006Cordis Neurovascular, IncExpandable stent and delivery system
US7004954 *Dec 19, 2002Feb 28, 2006Endovascular Technologies, Inc.Device for removal of thrombus through physiological adhesion
US7004956 *Apr 25, 2003Feb 28, 2006Endovascular Technologies, Inc.Embolic basket
US7156871 *Oct 28, 2004Jan 2, 2007Cordis Neurovascular, Inc.Expandable stent having a stabilized portion
US7179269 *May 20, 2002Feb 20, 2007Scimed Life Systems, Inc.Apparatus and system for removing an obstruction from a lumen
US7179273 *Aug 5, 2002Feb 20, 2007Endovascular Technologies, Inc.Filter/emboli extractor for use in variable sized blood vessels
US7182774 *Feb 9, 2004Feb 27, 2007Cordis CorporationHeated vascular occlusion coil deployment system
US7195648 *Apr 29, 2003Mar 27, 2007Cordis Neurovascular, Inc.Intravascular stent device
US7201769 *Sep 20, 2004Apr 10, 2007Cordis Neurovascular, Inc.Expandable stent and delivery system
US7323000 *Oct 30, 2000Jan 29, 2008Dendron GmbhDevice for implanting of occlusion spirals
US7344500 *Jul 27, 2004Mar 18, 2008Medtronic Minimed, Inc.Sensing system with auxiliary display
US7344550 *Oct 21, 2003Mar 18, 2008Boston Scientific Scimed, Inc.Clot removal device
US7344558 *Feb 28, 2006Mar 18, 2008Cordis Development CorporationEmbolic device delivery system
US7357809 *Jun 30, 2005Apr 15, 2008Cordis Neurovascular, Inc.Chemically based vascular occlusion device deployment with gripping feature
US7481821 *Nov 12, 2002Jan 27, 2009Thomas J. FogartyEmbolization device and a method of using the same
US7510565 *Jan 5, 2006Mar 31, 2009Salviac LimitedEmbolic protection device
US7517352 *Mar 27, 2001Apr 14, 2009Bacchus Vascular, Inc.Devices for percutaneous remote endarterectomy
US7524319 *Jun 14, 2004Apr 28, 2009Artemis Medical, Inc.Particle-removing medical device and method
US20040059407 *Feb 12, 2003Mar 25, 2004Angeli EscamillaExpandable stent and delivery system
US20040078050 *Oct 30, 2000Apr 22, 2004Hermann MonstadtDevice for implanting occlusion coils
US20050021125 *Aug 24, 2004Jan 27, 2005Stack Richard S.Stent delivery catheter and method of use
US20050033348 *May 5, 2004Feb 10, 2005Concentric Medical, Inc.Systems, methods and devices for removing obstructions from a blood vessel
US20050049619 *Sep 4, 2004Mar 3, 2005Concentric Medical, Inc.Systems, methods and devices for removing obstructions from a blood vessel
US20050059995 *Oct 25, 2004Mar 17, 2005Concentric Medical, Inc., A Delaware CorporationSystems, methods and devices for removing obstructions from a blood vessel
US20050085849 *Oct 25, 2004Apr 21, 2005Concentric Medical, Inc., A Delaware CorporationSystems, methods and devices for removing obstructions from a blood vessel
US20060064114 *Sep 22, 2005Mar 23, 2006Terumo Kabushiki KaishaWire to remove intravascular foreign body and medical instrument
US20070038226 *Jul 27, 2006Feb 15, 2007Galdonik Jason AEmbolectomy procedures with a device comprising a polymer and devices with polymer matrices and supports
US20080082107 *Jul 21, 2006Apr 3, 2008John MillerDevices and methods for removing obstructions from a cerebral vessel
US20090069828 *Sep 10, 2007Mar 12, 2009Lazarus Effect, Inc.Articulating retrieval devices
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US8066757Dec 28, 2010Nov 29, 2011Mindframe, Inc.Blood flow restoration and thrombus management methods
US8070791Dec 29, 2010Dec 6, 2011Mindframe, Inc.Multiple layer embolus removal
US8088140May 29, 2009Jan 3, 2012Mindframe, Inc.Blood flow restorative and embolus removal methods
US8147534May 25, 2005Apr 3, 2012Tyco Healthcare Group LpSystem and method for delivering and deploying an occluding device within a vessel
US8167903 *Jun 4, 2008May 1, 2012Cook Medical Technologies LlcDevice for retrieving a foreign object located in a body vessel
US8197493Dec 29, 2010Jun 12, 2012Mindframe, Inc.Method for providing progressive therapy for thrombus management
US8236042Apr 8, 2009Aug 7, 2012Tyco Healthcare Group LpSystem and method for delivering and deploying an occluding device within a vessel
US8257421Apr 6, 2009Sep 4, 2012Tyco Healthcare Group LpSystem and method for delivering and deploying an occluding device within a vessel
US8267985May 24, 2006Sep 18, 2012Tyco Healthcare Group LpSystem and method for delivering and deploying an occluding device within a vessel
US8273101Apr 20, 2009Sep 25, 2012Tyco Healthcare Group LpSystem and method for delivering and deploying an occluding device within a vessel
US8382825Mar 10, 2011Feb 26, 2013Covidien LpFlexible vascular occluding device
US8394119Feb 28, 2012Mar 12, 2013Covidien LpStents having radiopaque mesh
US8398701May 25, 2005Mar 19, 2013Covidien LpFlexible vascular occluding device
US8460312Mar 28, 2011Jun 11, 2013Penumbra, Inc.System and method for treating ischemic stroke
US8545514Apr 10, 2009Oct 1, 2013Covidien LpMonorail neuro-microcatheter for delivery of medical devices to treat stroke, processes and products thereby
US8574262Sep 26, 2011Nov 5, 2013Covidien LpRevascularization devices
US8585713Oct 25, 2011Nov 19, 2013Covidien LpExpandable tip assembly for thrombus management
US8617234May 24, 2006Dec 31, 2013Covidien LpFlexible vascular occluding device
US8623067Apr 17, 2009Jan 7, 2014Covidien LpMethods and apparatus for luminal stenting
US8628564Apr 17, 2009Jan 14, 2014Covidien LpMethods and apparatus for luminal stenting
US8632584Nov 5, 2007Jan 21, 2014Dendron GmbhMedical implant having a curlable matrix structure and method of use
US8636760Aug 28, 2012Jan 28, 2014Covidien LpSystem and method for delivering and deploying an occluding device within a vessel
US8679142Nov 15, 2012Mar 25, 2014Covidien LpMethods and apparatus for flow restoration
US8715316Aug 29, 2013May 6, 2014Insera Therapeutics, Inc.Offset vascular treatment devices
US8715317Dec 2, 2013May 6, 2014Insera Therapeutics, Inc.Flow diverting devices
US8721676Aug 28, 2013May 13, 2014Insera Therapeutics, Inc.Slotted vascular treatment devices
US8721677Dec 18, 2013May 13, 2014Insera Therapeutics, Inc.Variably-shaped vascular devices
US8728116Aug 29, 2013May 20, 2014Insera Therapeutics, Inc.Slotted catheters
US8728117Dec 2, 2013May 20, 2014Insera Therapeutics, Inc.Flow disrupting devices
US8733618Aug 28, 2013May 27, 2014Insera Therapeutics, Inc.Methods of coupling parts of vascular treatment systems
US8735777Aug 29, 2013May 27, 2014Insera Therapeutics, Inc.Heat treatment systems
US8753371Nov 25, 2013Jun 17, 2014Insera Therapeutics, Inc.Woven vascular treatment systems
US8783151Aug 28, 2013Jul 22, 2014Insera Therapeutics, Inc.Methods of manufacturing vascular treatment devices
US8784446Mar 25, 2014Jul 22, 2014Insera Therapeutics, Inc.Circumferentially offset variable porosity devices
US8789452Aug 28, 2013Jul 29, 2014Insera Therapeutics, Inc.Methods of manufacturing woven vascular treatment devices
US8790365Mar 25, 2014Jul 29, 2014Insera Therapeutics, Inc.Fistula flow disruptor methods
US8795330Mar 25, 2014Aug 5, 2014Insera Therapeutics, Inc.Fistula flow disruptors
US8803030Mar 25, 2014Aug 12, 2014Insera Therapeutics, Inc.Devices for slag removal
US8813625Jan 29, 2014Aug 26, 2014Insera Therapeutics, Inc.Methods of manufacturing variable porosity flow diverting devices
US8816247Mar 25, 2014Aug 26, 2014Insera Therapeutics, Inc.Methods for modifying hypotubes
US8828045Mar 25, 2014Sep 9, 2014Insera Therapeutics, Inc.Balloon catheters
US8845678Aug 28, 2013Sep 30, 2014Insera Therapeutics Inc.Two-way shape memory vascular treatment methods
US8845679Jan 29, 2014Sep 30, 2014Insera Therapeutics, Inc.Variable porosity flow diverting devices
US8852227Aug 29, 2013Oct 7, 2014Insera Therapeutics, Inc.Woven radiopaque patterns
US8859934Mar 25, 2014Oct 14, 2014Insera Therapeutics, Inc.Methods for slag removal
US8863631Jan 29, 2014Oct 21, 2014Insera Therapeutics, Inc.Methods of manufacturing flow diverting devices
US8866049Mar 25, 2014Oct 21, 2014Insera Therapeutics, Inc.Methods of selectively heat treating tubular devices
US8869670Jan 29, 2014Oct 28, 2014Insera Therapeutics, Inc.Methods of manufacturing variable porosity devices
US8870901Aug 28, 2013Oct 28, 2014Insera Therapeutics, Inc.Two-way shape memory vascular treatment systems
US8870910Dec 2, 2013Oct 28, 2014Insera Therapeutics, Inc.Methods of decoupling joints
US8872068Mar 25, 2014Oct 28, 2014Insera Therapeutics, Inc.Devices for modifying hypotubes
US8882797Apr 22, 2014Nov 11, 2014Insera Therapeutics, Inc.Methods of embolic filtering
US8895891Jan 29, 2014Nov 25, 2014Insera Therapeutics, Inc.Methods of cutting tubular devices
US8904914Apr 22, 2014Dec 9, 2014Insera Therapeutics, Inc.Methods of using non-cylindrical mandrels
US8910555Apr 22, 2014Dec 16, 2014Insera Therapeutics, Inc.Non-cylindrical mandrels
US8926680Jun 10, 2008Jan 6, 2015Covidien LpAneurysm neck bridging processes with revascularization systems methods and products thereby
US8932320Apr 16, 2014Jan 13, 2015Insera Therapeutics, Inc.Methods of aspirating thrombi
US8932321Apr 24, 2014Jan 13, 2015Insera Therapeutics, Inc.Aspiration systems
US8940003Feb 20, 2009Jan 27, 2015Covidien LpMethods and apparatus for flow restoration
US8945143Jun 24, 2013Feb 3, 2015Covidien LpExpandable tip assembly for thrombus management
US8945172Dec 30, 2011Feb 3, 2015Covidien LpDevices for restoring blood flow and clot removal during acute ischemic stroke
US8992441Jun 21, 2014Mar 31, 2015Transmed7, LlcAutomated, selectable, soft tissue excision biopsy devices and methods
US9034007Sep 21, 2007May 19, 2015Insera Therapeutics, Inc.Distal embolic protection devices with a variable thickness microguidewire and methods for their use
US9039633Jul 3, 2013May 26, 2015Transmed7, LlcAutomated, selectable, soft tissue excision biopsy devices and methods
US9039749Oct 1, 2010May 26, 2015Covidien LpMethods and apparatuses for flow restoration and implanting members in the human body
US9050205Jul 20, 2012Jun 9, 2015Covidien LpMethods and apparatus for luminal stenting
US9095343Feb 29, 2012Aug 4, 2015Covidien LpSystem and method for delivering and deploying an occluding device within a vessel
US9114001Mar 14, 2013Aug 25, 2015Covidien LpSystems for attaining a predetermined porosity of a vascular device
US9119625Oct 5, 2012Sep 1, 2015Pulsar Vascular, Inc.Devices, systems and methods for enclosing an anatomical opening
US9119656May 7, 2013Sep 1, 2015Penumbra, Inc.System and method for treating ischemic stroke
US9125659Mar 18, 2013Sep 8, 2015Covidien LpFlexible vascular occluding device
US9155647Jul 18, 2012Oct 13, 2015Covidien LpMethods and apparatus for luminal stenting
US9157174Mar 14, 2013Oct 13, 2015Covidien LpVascular device for aneurysm treatment and providing blood flow into a perforator vessel
US9161766Dec 20, 2013Oct 20, 2015Covidien LpMethods and apparatus for flow restoration
US9179931Aug 28, 2013Nov 10, 2015Insera Therapeutics, Inc.Shape-set textile structure based mechanical thrombectomy systems
US9179995Aug 28, 2013Nov 10, 2015Insera Therapeutics, Inc.Methods of manufacturing slotted vascular treatment devices
US9198666Jul 16, 2012Dec 1, 2015Covidien LpSystem and method for delivering and deploying an occluding device within a vessel
US9198687 *May 19, 2008Dec 1, 2015Covidien LpAcute stroke revascularization/recanalization systems processes and products thereby
US9204983Aug 28, 2012Dec 8, 2015Covidien LpSystem and method for delivering and deploying an occluding device within a vessel
US9220522Jul 30, 2008Dec 29, 2015Covidien LpEmbolus removal systems with baskets
US9259229Mar 14, 2013Feb 16, 2016Pulsar Vascular, Inc.Systems and methods for enclosing an anatomical opening, including coil-tipped aneurysm devices
US9277924Sep 3, 2010Mar 8, 2016Pulsar Vascular, Inc.Systems and methods for enclosing an anatomical opening
US9295568Sep 17, 2013Mar 29, 2016Covidien LpMethods and apparatus for luminal stenting
US9301831Mar 14, 2013Apr 5, 2016Covidien LpMethods for attaining a predetermined porosity of a vascular device
US9314324Sep 8, 2015Apr 19, 2016Insera Therapeutics, Inc.Vascular treatment devices and methods
US9320532Feb 2, 2015Apr 26, 2016Covidien LpExpandable tip assembly for thrombus management
US9320590Mar 11, 2013Apr 26, 2016Covidien LpStents having radiopaque mesh
US9381104Jul 16, 2012Jul 5, 2016Covidien LpSystem and method for delivering and deploying an occluding device within a vessel
US9387098Oct 15, 2013Jul 12, 2016Covidien LpRevascularization devices
US9393021Feb 25, 2013Jul 19, 2016Covidien LpFlexible vascular occluding device
US9408621 *Jun 3, 2014Aug 9, 2016Boston Scientific Scimed, Inc.Medical retrieval devices and related methods of use
US9452070Oct 31, 2012Sep 27, 2016Covidien LpMethods and systems for increasing a density of a region of a vascular device
US9510835Sep 9, 2013Dec 6, 2016Pulsar Vascular, Inc.Methods and systems for endovascularly clipping and repairing lumen and tissue defects
US9561122Oct 6, 2015Feb 7, 2017Covidien LpVascular device for aneurysm treatment and providing blood flow into a perforator vessel
US9592068Nov 24, 2014Mar 14, 2017Insera Therapeutics, Inc.Free end vascular treatment systems
US9610181Apr 25, 2016Apr 4, 2017Covidien LpStents having radiopaque mesh
US9615831Feb 10, 2015Apr 11, 2017Pulsar Vascular, Inc.Systems and methods for supporting or occluding a physiological opening or cavity
US9636117Jul 24, 2015May 2, 2017Pulsar Vascular, Inc.Devices, systems and methods for enclosing an anatomical opening
US9655633Oct 5, 2011May 23, 2017Penumbra, Inc.System and method for treating ischemic stroke
US9675482May 13, 2009Jun 13, 2017Covidien LpBraid implant delivery systems
US9750524Oct 29, 2015Sep 5, 2017Insera Therapeutics, Inc.Shape-set textile structure based mechanical thrombectomy systems
US9801744May 18, 2015Oct 31, 2017Covidien LpMethods and apparatus for luminal stenting
US20090306678 *Jun 4, 2008Dec 10, 2009Cook IncorporatedDevice for retrieving a foreign object located in a body vessel
US20100022951 *May 20, 2009Jan 28, 2010Luce, Forward, Hamilton 7 Scripps, LlpDetachable hub/luer device and processes
US20110172700 *Mar 28, 2011Jul 14, 2011Penumbra, Inc.System and method for treating ischemic stroke
US20110190797 *Apr 12, 2011Aug 4, 2011Mindframe, Inc.Method of restoring blood flow through an obstructed blood vessel of the brain
US20110204790 *Feb 23, 2010Aug 25, 2011General Electric CompanyLighting system with thermal management system
US20120016406 *Sep 26, 2011Jan 19, 2012Mindframe, Inc.Flow restoration methods
US20140100457 *Oct 8, 2013Apr 10, 2014Olympus Medical Systems Corp.Treatment instrument for endoscope
US20140107459 *Oct 11, 2012Apr 17, 2014Alcon Research, Ltd.Devices, systems, and methods for intraocular measurements
US20150066049 *Jun 3, 2014Mar 5, 2015Boston Scientific Scimed, Inc.Medical retrieval devices and related methods of use
US20150148838 *Nov 26, 2013May 28, 2015Novartis AgSystems and Methods for a Surgical Tissue Manipulator
CN103431907A *Sep 25, 2013Dec 11, 2013河南科技大学Percutaneous nephroscope set calculus removing lens with lockable calculus crushing end
CN104053410A *Oct 4, 2012Sep 17, 2014半影公司System and method for treating ischemic stroke
CN104207828A *Sep 21, 2014Dec 17, 2014李峰Pneumatic foreign body forceps
CN105073037A *Nov 7, 2013Nov 18, 2015转化医药7有限责任公司Automated, selectable, soft tissue excision biopsy devices and methods
CN105434012A *Aug 4, 2014Mar 30, 2016李峰Body structure of tracheal foreign body forceps
CN105434012B *Aug 4, 2014Jul 18, 2017陈军一种气管异物钳钳体结构
CN105596063A *Sep 21, 2014May 25, 2016李峰Foreign body forceps head for surgery
CN105615962A *Aug 4, 2014Jun 1, 2016李峰Forceps device for tracheal foreign bodies
CN105615963A *Sep 21, 2014Jun 1, 2016李峰Head of pneumatic foreign body forceps
EP2903538A4 *Oct 2, 2013Sep 14, 2016Univ ToledoMinimally invasive thrombectomy invention
WO2012167137A1 *Jun 1, 2012Dec 6, 2012Pulsar Vascular, Inc.Systems and methods for capturing and removing blood clots
WO2013052625A1 *Oct 4, 2012Apr 11, 2013Penumbra, Inc.System and method for treating ischemic stroke
WO2014105271A1 *Nov 7, 2013Jul 3, 2014Transmed7, LlcAutomated, selectable, soft tissue excision biopsy devices and methods
WO2015165474A1 *Apr 29, 2015Nov 5, 2015Coloplast A/SA snare instrument with a distal snare structure
WO2016089865A1 *Dec 1, 2015Jun 9, 2016Merit Medical Systems, Inc.Medical grasping device
Classifications
U.S. Classification606/127
International ClassificationA61B17/221
Cooperative ClassificationA61B2017/2212, A61B17/221, A61B2017/2215, A61B2017/22034
European ClassificationA61B17/221
Legal Events
DateCodeEventDescription
Dec 19, 2007ASAssignment
Owner name: CHESTNUT MEDICAL TECHNOLOGIES, CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:GARCIA, ADRIAN;YE, TING TINA;TRAN, QUANG Q.;AND OTHERS;REEL/FRAME:020266/0457
Effective date: 20071211