Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberUS20100185234 A1
Publication typeApplication
Application numberUS 12/688,065
Publication dateJul 22, 2010
Priority dateJan 16, 2009
Also published asUS20140364900
Publication number12688065, 688065, US 2010/0185234 A1, US 2010/185234 A1, US 20100185234 A1, US 20100185234A1, US 2010185234 A1, US 2010185234A1, US-A1-20100185234, US-A1-2010185234, US2010/0185234A1, US2010/185234A1, US20100185234 A1, US20100185234A1, US2010185234 A1, US2010185234A1
InventorsAaron M. Fortson, Wouter E. Roorda
Original AssigneeAbbott Vascular Inc.
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Closure devices, systems, and methods
US 20100185234 A1
Abstract
The present disclosure includes vessel closure devices, systems, and methods. A closure device configured to close an opening in a body lumen may include an elongate member having a distal end and a proximal end. An anchor member may be disposed on the elongate member proximate the distal end of the elongate member. A cap member may also be disposed on the elongate member a distance from the distal end of the elongate member. The anchor member and the cap member cooperate to close the opening in the body lumen.
Images(14)
Previous page
Next page
Claims(28)
1. A closure device configured to close an opening in a body lumen, the closure device comprising:
an elongate member having a distal end and a proximal end;
an anchor member disposed on the elongate member proximate the distal end of the elongate member; and
a cap member disposed on the elongate member a distance from the distal end of the elongate member, wherein the anchor member and the cap member are positioned to close the opening in the body lumen.
2. The closure device of claim 1, wherein the elongate member comprises a metal or plastic shaft.
3. The closure device of claim 1, wherein the elongate member comprises a suture.
4. The closure device of claim 3, further comprising a second elongate member disposed substantially in parallel with the first elongate member, the second elongate member comprising a suture.
5. The closure device of claim 1, wherein the elongate member comprises a hollow shaft and the closure device further comprises a plug configured to be inserted into the hollow shaft to expand the hollow shaft.
6. The closure device of claim 1, wherein the elongate member comprises one or more projections disposed along the length thereof.
7. The closure device of claim 6, wherein the one or more projections are chosen from a group comprising teeth, barbs, and ridges.
8. The closure device of claim 6, wherein the one or more projections are configured to permit movement by the cap member in a distal direction and resist movement by the cap member in a proximal direction.
9. The closure device of claim 1, wherein the cap member is slidably disposed on the elongate member.
10. The closure device of claim 1, wherein the anchor member or cap member comprises a biodegradable material.
11. The closure device of claim 1, wherein the anchor member or cap member is disc shaped.
12. The closure device of claim 1, wherein the anchor member or cap member has a varying thickness.
13. The closure device of claim 1, wherein the elongate member comprises a bioabsorbable monofilament.
14. The closure device of claim 1, wherein the anchor member is coupled to the elongate member proximate a knot.
15. The closure device of claim 1, further comprising a cleat, collet, or knot disposed on the elongate member proximal of the cap member.
16. A closure system comprising:
a generally tubular outer member having a distal opening and a proximal opening;
a generally tubular intermediate member disposed at least partially within the outer member; and
a closure device disposed at least partially within the outer member, the closure device comprising:
an elongate member having a distal end and a proximal end, the elongate member being disposed at least partially through the intermediate member;
an anchor member disposed on the elongate member proximate the distal end of the elongate member, the anchor member being further disposed within the outer member distal of the intermediate member; and
a cap member disposed on the elongate member a distance from the distal end of the elongate member, the cap member being further disposed within the outer member proximal of the anchor member.
17. The closure system of claim 16, wherein the outer member comprises a non-rigid catheter.
18. The closure system of claim 16, further comprising a generally tubular inner member disposed at least partially within the outer member and/or intermediate member.
19. The closure system of claim 18, wherein the inner member comprises a guidewire lumen, fluid marker port, and/or flow back lumen.
20. The closure system of claim 18, wherein the inner member and the intermediate member are integrated together into a single component.
21. The closure system of claim 16, wherein the intermediate member comprises a pusher tube.
22. The closure system of claim 16, wherein the intermediate member is movable relative to the outer member.
23. The closure system of claim 22, wherein the distal movement of the intermediate member relative to the outer member is limited to the movement necessary deploy the anchor member from the distal opening of the outer member.
24. The closure system of claim 16, further comprising a collagen or polyethylene glycol plug configured to at least partially obstruct a tissue tract proximate a body lumen opening.
25. A method of closing an opening in a lumen wall, the method comprising:
advancing the distal end of a closure system over a guidewire into a body lumen, the closure system comprising:
a generally tubular outer member having a distal opening and a proximal opening;
a generally tubular intermediate member disposed at least partially within the outer member; and
a closure device disposed at least partially within the outer member, the closure device comprising:
an elongate member having a distal end and a proximal end, the elongate member being disposed at least partially through the intermediate member;
an anchor member disposed on the elongate member proximate the distal end of the elongate member, the anchor member being further disposed within the outer member distal of the intermediate member; and
a cap member disposed on the elongate member a distance from the distal end of the elongate member, the cap member being further disposed within the outer member proximal of the anchor member.
deploying the anchor member into the lumen;
tensioning the elongate member to engage the anchor member with a distal surface of the lumen wall; and
deploying the cap member and advancing the cap member in a distal direction along the elongate member to engage a proximal surface of the lumen wall.
26. The method of claim 25, further comprising positioning a knot, collet, or cleat on the elongate member proximal of the cap member.
27. The method of claim 25, further comprising retracting the outer member in a proximal direction to deploy the cap member.
28. The method of claim 25, wherein the closure system further comprises a generally tubular inner member disposed at least partially within the intermediate member.
Description
    CROSS-REFERENCE TO RELATED APPLICATIONS
  • [0001]
    This U.S. patent application claims the benefit of and priority to U.S. Provisional Patent Application having Ser. No. 61/145,468, filed on Jan. 16, 2009, the disclosure of which is incorporated herein by reference in its entirety.
  • BACKGROUND
  • [0002]
    1. Technical Field
  • [0003]
    The present disclosure relates generally to medical devices, systems, and methods. In particular, the present disclosure relates to vessel closure devices, systems, and methods.
  • [0004]
    2. Technology
  • [0005]
    Catheterization and interventional procedures, such as angioplasty or stenting, generally are performed by inserting a hollow needle through a patient's skin and tissue into the patient's vascular system. A guidewire may be advanced through the needle and into the patient's blood vessel accessed by the needle. The needle is then removed, enabling an introducer sheath to be advanced over the guidewire into the vessel, e.g., in conjunction with or subsequent to a dilator.
  • [0006]
    A catheter or other device may then be advanced through a lumen of the introducer sheath and over the guidewire into a position for performing a medical procedure. Thus, the introducer sheath may facilitate introducing various devices into the vessel, while minimizing trauma to the vessel wall and/or minimizing blood loss during a procedure.
  • [0007]
    Upon completing the procedure, the devices and introducer sheath are removed, leaving a puncture site in the vessel wall. Traditionally, external pressure is applied to the puncture site until clotting and wound sealing occur; however, the patient must remain bedridden for a substantial period after clotting to ensure closure of the wound. This procedure, however, may be time consuming and expensive, requiring as much as an hour of a physician's or nurse's time. It is also uncomfortable for the patient and requires that the patient remain immobilized in the operating room, catheter lab, or holding area. In addition, a risk of hematoma exists from bleeding before hemostasis occurs.
  • BRIEF SUMMARY
  • [0008]
    The present disclosure includes vessel closure devices, systems, and methods. In particular, the devices, systems, and methods of the present disclosure may allow a medical service provider to efficiently and quickly close an opening in a body lumen in a cost effective manner. In addition, the devices, systems, and methods of the present disclosure may allow for the closing of smaller body lumen openings using fewer parts than prior devices and systems.
  • [0009]
    According to one embodiment of the present disclosure, a closure device configured to close an opening in a body lumen may include an elongate member having a distal end and a proximal end. In addition, an anchor member may be disposed on the elongate member proximate the distal end of the elongate member. A cap member may also be disposed on the elongate member a distance from the distal end of the elongate member.
  • [0010]
    These and other advantages and features of the present disclosure will become more fully apparent from the following description and appended claims, or may be learned by the practice of the invention as set forth hereinafter.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0011]
    To further clarify the advantages and features of the present disclosure, a more particular description of the disclosure will be rendered by reference to example embodiments thereof which are illustrated in the appended drawings. It is appreciated that these drawings depict only example embodiments of the disclosure and are therefore not to be considered limiting of its scope. The example embodiments will be described and explained with additional specificity and detail through the use of the accompanying drawings in which:
  • [0012]
    FIG. 1 illustrates an example closure device for closing an opening in a body lumen or other tissue;
  • [0013]
    FIG. 2 illustrates an another example closure device for closing an opening in a body lumen or other tissue;
  • [0014]
    FIG. 3A illustrates an example closure system for closing an opening in a body lumen or other tissue;
  • [0015]
    FIG. 3B illustrates an additional example closure system;
  • [0016]
    FIG. 3C illustrates a further example closure system; and
  • [0017]
    FIGS. 4-11 illustrate an example method of closing a lumen opening.
  • DETAILED DESCRIPTION
  • [0018]
    The present disclosure includes devices, systems, and methods for closing an opening in a body lumen or other tissue. In particular, an example closure system may allow for at least one of reduced production costs, ease of use, and more effective hemostasis. In addition, embodiments of the closure system disclosed herein may allow for the closure of smaller openings in body lumens or other tissue.
  • [0019]
    In one embodiment, the closure system may include a closure device. The closure device may include an elongate member, such as a suture or shaft, an anchor member (or foot), and a cap member. The closure device may be disposed within or deployed by the closure system. The closure system may include an outer member, an inner member, an intermediate member, or combinations thereof configured to deploy a closure device from the closure system.
  • [0020]
    Reference is now made to FIG. 1, which illustrates an example closure device 100. The closure device 100 may include a plurality of closure members 110 coupled to an elongate member 120. In particular, the plurality of closure members 110 may include an anchor member 110 a and/or a cap member 110 b. In one embodiment, the anchor member 110 a may be disposed near a distal end of the elongate member 120. In a further embodiment, the cap member 110 b may be proximate the anchor member 110 a and/or spaced a distance away from the distal end of the elongate member 120.
  • [0021]
    The anchor member 110 a may be configured to be deployed through an opening in a body lumen in order to secure the closure device 100 from a point distal to the lumen opening. For example, the anchor member 110 a may be configured to move from a compressed, folded, or compacted first position having a dimension smaller than a lumen opening to a deployed, unfolded, or expanded second position having a dimension larger than the lumen opening. As a result, the anchor member 110 a may pass through the lumen opening while in the first position and thereafter may move to the second position and provide an anchor against the distal side of the lumen wall proximate the lumen opening.
  • [0022]
    The elongate member 120 may extend proximally from the deployed anchor member 110 a and/or may be tensioned to secure the anchor member 110 a proximate the lumen opening and/or against a distal surface of a lumen wall once deployed. In a further embodiment, the elongate member 120 may pass through the cap member 110 b, which may be deployed at a position proximal of the lumen wall. Once deployed, the cap member 110 b may be moved in a distal direction and/or may engage the proximal surface of the lumen wall. As a result, the anchor member 110 a and/or cap member 110 b may at least partially close the lumen opening.
  • [0023]
    The closure device 100 including, but not limited to, the anchor member 110 a and/or cap member 110 b, may include one or more biocompatible, bioabsorbable, bioresorbable, other materials, or combinations thereof. Examples of such materials may include a suitable hydrogel, hydrophilic polymer, biodegradable polymers, bioabsorbable polymers and bioneutral polymers. Examples of such polymers may include poly(alpha-hydroxy esters), polylactic acids, polylactides, poly-L-lactide, poly-DL-lactide, poly-L-lactide-co-DL-lactide, polyglycolic acids, polyglycolide, polylactic-co-glycolic acids, polyglycolide-co-lactide, polyglycolide-co-DL-lactide, polyglycolide-co-L-lactide, polyanhydrides, polyanhydride-co-imides, polyesters, polyorthoesters, polycaprolactones, polyesters, polyanydrides, polyphosphazenes, polyester amides, polyester urethanes, polycarbonates, polytrimethylene carbonates, polyglycolide-co-trimethylene carbonates, poly(PBA-carbonates), polyfumarates, polypropylene fumarate, poly(p-dioxanone), polyhydroxyalkanoates, polyamino acids, poly-L-tyrosines, poly(beta-hydroxybutyrate), polyhydroxybutyrate-hydroxyvaleric acids, combinations thereof, and/or the like.
  • [0024]
    In one embodiment, the closure device 100, including, but not limited to, the anchor member 110 a and/or cap member 110 b, may be coated with an active pharmaceutical ingredient with or without a polymeric carrier. The active pharmaceutical ingredient can be any drug. In one embodiment, the pharmaceutical ingredient may increase tissue growth.
  • [0025]
    The polymeric coating and drug may be configured to cooperate so as to form a diffusion pathway (e.g., lipophilic, hydrophilic, and/or amphipathic) with tissue when at least a portion of the closure device 100 engages tissue. This may facilitate diffusion into the tissue instead of into a body fluid passing over the closure device 100.
  • [0026]
    The closure device 100 or any portion thereof may be loaded with and deliver beneficial agents or drugs, such as therapeutic agents, pharmaceuticals and radiation therapies. Accordingly, the closure device 100 and/or coating material may contain a drug or beneficial agent to improve the use of the closure device 100. Such drugs or beneficial agents may include antithrombotics, anticoagulants, antiplatelet agents, thrombolytics, antiproliferatives, anti-inflammatories, hemostatic agents, agents that inhibit hyperplasia, inhibitors of smooth muscle proliferation, antibiotics, growth factor inhibitors, or cell adhesion inhibitors, as well as antineoplastics, antimitotics, antifibrins, antioxidants, agents that promote endothelial cell recovery, antiallergic substances, radiopaque agents, viral vectors having beneficial genes, genes, siRNA, antisense compounds, oligionucleotides, cell permeation enhancers, and combinations thereof. Another example of a suitable beneficial agent is described in U.S. Pat. No. 6,015,815 and U.S. Pat. No. 6,329,386 entitled “Tetrazole-containing rapamycin analogs with shortened half-lives”, the entireties of which are herein incorporated by reference.
  • [0027]
    The anchor member 110 a and/or cap member 110 b may include any shape configured to facilitate obstruction of a lumen opening. In one embodiment, the anchor member 110 a and/or cap member 110 b may have a disc-like shape. For example, the anchor member 110 a and/or cap member 110 b may include a generally flat piece of material that may be circular or oval in shape. The anchor member 110 a and/or cap member 110 b may incorporate other shapes and/or configurations. For example, the anchor member 110 a and/or cap member 110 b may have an elliptical and/or polygonal shape. In a further embodiment, the closure members 110 may be rectangular in shape along the length thereof with rounded and/or triangular ends or corners.
  • [0028]
    In one implementation, the thickness of the anchor member 110 a and/or cap member 110 b may be continuous throughout the anchor member 110 a and/or cap member 110 b. In further implementations, however, the thickness of the anchor member 110 a and/or cap member 110 b may vary as desired for a particular application. For example, the thickness of the anchor member 110 a and/or cap member 110 b may be greater near the center than along the outer edge of the anchor member 110 a and/or cap member 110 b. In a yet further example, the thickness of the anchor member 110 a and/or cap member 110 b may be greater along a first axis extending through the center of the anchor member 110 a and/or cap member 110 b and progressively thinner extending away from the first axis. As a result, the anchor member 110 a and/or cap member 110 b may allow bending about the first axis but may resist bending about an axis perpendicular to or different from the first axis. In yet further implementations, the thickness of the anchor member 110 a and/or cap member 110 b may vary as desired to achieve a particular strength, rigidity, flexibility, and/or other mechanical property.
  • [0029]
    In one implementation, the anchor member 110 a and cap member 110 b may have the same shape, size, coating, and/or other characteristics, and/or combinations thereof. In a further embodiment, the shape, size, coating, and/or other characteristics of the anchor member 110 a may be different than those of the cap member 110 b.
  • [0030]
    As mentioned, the closure device 100 may include an elongate member 120. In one embodiment, the anchor member 110 a may be coupled to a distal end of the elongate member 120 and/or the cap member 110 b may be disposed on the elongate member 120 at a position along the length of the elongate member 120. The elongate member 120 may include one or more bioabsorbable materials and/or beneficial agents, such as any bioabsorbable material and/or beneficial agents disclosed herein. In a further embodiment, the elongate member 120 may include a bioabsorbable metal, alloy, polymer, plastic, composite, other materials, or combinations thereof. The elongate member 120 may include a single limb, such as disclosed in FIG. 1, or may include a plurality of limbs, such as disclosed in FIG. 2. In one example embodiment, the elongate member 120 may include a suture or a plurality of sutures. In a further embodiment, the elongate member 120 may include an elongate shaft or a plurality of elongate shafts. In a yet further embodiment, at least a portion of the elongate member 120 may be generally tubular or hollow.
  • [0031]
    The closure device 100 may be configured to resist proximal movement of the cap member 110 b and/or distal movement of the anchor member 110 a after deployment. For example, in one embodiment, a knot may be disposed on the elongate member 120 proximal of the cap member 110 b to secure the cap member 110 b and/or anchor member 110 a in place. In a further embodiment, a cleat, such as a bioabsorbable plastic cleat, may be positioned to secure the cap member 110 b and/or anchor member 110 a in place. For example, the cleat may be positioned along the elongate member 120 proximal of and/or abutting the cap member 110 b. The cleat may maintain sufficient tension in the elongate member 120 to maintain the cap member 110 b and anchor member 110 a securely in a deployed position, such as in apposition with the lumen wall and/or lumen opening therebetween. In particular, the anchor member 110 a and cap member 110 b may sandwich the lumen wall surrounding a lumen opening to achieve closure of the lumen opening.
  • [0032]
    In a further embodiment, the closure device 100 may include a mechanism to lock and/or secure the anchor member 110 a and cap member 110 b in place. In one example embodiment, the elongate member 120 may have a uniform thickness along its length and/or pass through an aperture in the cap member 110 b configured to produce sufficient frictional force between the cap member 110 b and elongate member 120 to resist relative movement between the elongate member 120 and cap member 110 b. In particular, this configuration may allow the cap member 110 b to be deployed by sliding the cap member 110 b in a distal direction along the elongate member 120 to secure the cap member 110 b and anchor member 110 a in place. Once deployed, the frictional force between the elongate member 120 and the cap member 110 b may prevent and/or resist further movement by the cap member 110 b and/or anchor member 110 a.
  • [0033]
    In a further embodiment, the closure device 100 may include a barbed and/or ratchet design to secure the cap member 110 b and anchor member 110 a in the deployed configuration. For example, the elongate member 120 may include a plurality of projections 125 disposed along the length thereof. The projections 125 may include barbs, teeth, ridges, and/or other similar projections. The projections 125 may be configured to allow the cap member 110 b to move in a distal direction but may resist/prevent movement by the cap member 110 b in a proximal direction. For example, the projections 125 may be angled and/or extend in a distal direction to allow the cap member 110 b to pass over the projections 125 in a distal direction but to prevent the cap member 110 b from then passing back over the projections 125 in a proximal direction. Accordingly, once the anchor member 110 a is deployed and/or secured against the distal surface of the lumen wall, the cap member 110 b may be advanced along the elongate member 120 over the projections 125. The cap member 110 b may be secured against the proximal surface of the lumen wall and/or held in place by one or more of the projections 125 of the elongate member 120.
  • [0034]
    In yet a further embodiment, the locking mechanism (i.e., knot, cleat, projections, etc.) may be independent of the cap member 110 b. In particular, decoupling the locking mechanism from the cap member 110 b may allow for the independent optimization of the locking mechanism and/or the cap member 110 b. For example, the closure device 100 may further include a sliding collet that may be advanced along the elongate member 120 and/or lock the cap member 110 b in place once deployed. The collet may incorporate one or more locking features that may be otherwise incorporated in the cap member 110 b as explained in more detail herein.
  • [0035]
    In a further embodiment, the cap member 110 b may be secured in place using a hollow elongate member 120 and a plug configured to be inserted into the elongate member 120. Once the anchor is deployed, the cap member 110 b may be moved along the hollow elongate member 120 into apposition with the anchor member 110 a, thereby applying pressure to opposite sides of the lumen wall near the lumen opening. A plug may be driven into the hollow elongate member 120 to expand the elongate member 120 proximal of the cap member 110 b. As a result, the expanded portion of the hollow elongate member 120 may secure the cap member 110 b in place by limiting movement by the cap member 110 b in a proximal direction.
  • [0036]
    Reference is now made to FIG. 2 which illustrates another example closure device. The example closure device 200 of this configuration may be functionally similar to the example closure device 100 previously described above and shown in FIG. 1 in most respects. Certain features will not be described in relation to this configuration where those components may function in the manner as described above and are hereby incorporated into this additional configuration described below. Like structures and/or components may be given like reference numerals.
  • [0037]
    In one embodiment, the closure device 200 may include a plurality of closure members 210 coupled to a plurality of elongate members 220 a, 220 b. The plurality of closure members 210 may include an anchor member 210 a and/or a cap member 210 b. In particular, the anchor member 210 a may be coupled to the distal ends of the elongate members 220 a, 220 b and/or the cap member 210 b may be disposed on the elongate members 220 a, 220 b proximal of the anchor member 210 a.
  • [0038]
    In one embodiment, the elongate members 220 a, 220 b may include plurality of sutures extending together along at least a portion of the length of the closure device 300. In a further example, the elongate members 220 a, 220 b may include shafts and/or sutures. The elongate members 220 a, 220 b may be coupled together and/or to the anchor member 210 a at their distal ends. For example, the elongate members 220 a, 220 b may be coupled together and/or coupled to the anchor member 210 a using a distal knot 230 a. In particular, the distal knot 230 a may be a heat formed knot. In a yet further embodiment, the elongate members 220 a, 220 b may form a proximal knot 230 b at a position proximal of the cap member 210 b. The proximal knot 230 b may be configured to be advanced in a distal direction and/or secure the cap member 210 b in apposition to the anchor member 210 a on opposite sides of a lumen wall. The elongate members 220 a, 220 b may be flexible and include surgical silk or thread, which may be bioabsorbable. Alternatively, the elongate member 120 (in FIG. 1) may be relatively stiff.
  • [0039]
    Reference is now made to FIG. 3A, which illustrates an example closure system 1000 for closing an opening in a body lumen or other tissue. In one embodiment, the closure system 1000 may include a closure device 300, a generally tubular outer member 1010, a generally tubular inner member 1030, and a generally tubular intermediate member 1020. The example closure device 300 included in the closure system 1000 of this configuration may be functionally similar to the example closure devices 100, 200 previously described above and shown in FIGS. 1-2 in most respects, where certain features will not be described in relation to this configuration wherein those components may function in the manner as described above and are hereby incorporated into this additional configuration described below. Like structures and/or components may be given like reference numerals.
  • [0040]
    In one embodiment, the closure device 300 may include an anchor member 310 a, a cap member 310 b, and an elongate member 320. The closure device 300 may be disposed at least partially within the outer member 1010 proximate a distal opening 1015 of the outer member 1010. The intermediate member 1020 may be disposed at least partially within the outer member 1010 proximal of the closure device 300. In particular, the distal end of the intermediate member 1020 may be disposed within the proximal end of the outer member 1010. The proximal end of the intermediate member 1020 may also extend out of the proximal end of the outer member 1010 for operation by a medical practitioner. The inner member 1030 may be disposed at least partially within the outer member 1010 and/or the intermediate member 1020. In a further embodiment, the closure device 300 may be disposed on or along side the inner member 1030. In particular, the anchor member 310 a and/or cap member 310 b may fold or wrap at least partially around the inner member 1030. The elongate member 320 of the closure device 300 may extend through a distal opening in the inner member 1030 and out a proximal opening in the inner member 1030 for operation by a medical practitioner.
  • [0041]
    The outer member 1010 may be configured to advance to a lumen opening while carrying the other components of the closure system 1000. In one embodiment, the outer member 1010 may have a generally tapered distal end to facilitate entry into a body lumen through a lumen opening. The outer member 1010 may have a distal opening 1015 through which the inner member 1030 may pass and through which the closure device 300 may be deployed. In one example embodiment, the outer member 1010 may include a non-rigid catheter.
  • [0042]
    In further implementations, the outer member 1010 may have any dimensions desired. For example, as shown in FIG. 3A, the outer member may have a substantially constant diameter along a majority of its length. However, in further implementations, the outer member 1010 may have a varying diameter. In a yet further implementation, the thickness of the outer member 1010 may vary along its length. For example, the thickness of the outer member may increase near the distal end. As a result, the inner diameter of the outer member may decrease near the distal end, creating a conical or funnel-like interior surface of the outer member 1010. The reduced inner diameter of the outer member 1010 may allow for a reduction of setting of the anchor member 310 a and/or cap member 310 b from age and/or sterilization. In a yet further implementation, the anchor member 310 a and/or cap member 310 b may be disposed with the outer member proximate its proximal end or within a handle portion of the closure system 1000 prior to deployment through the distal opening 1015 of the outer member 1010.
  • [0043]
    The intermediate member 1020 may be configured to deploy the anchor member 310 a and/or cap member 310 b of the closure device 300 through the distal opening 1015 in the outer member 1010. For example, the intermediate member 1020 may be disposed within the outer member 1010 and positioned proximal of and/or abutting the closure device 300. The intermediate member 1020 may be configured to translate in a distal direction relative to the outer member 1010 in order to push at least a portion of the closure device 300 through the distal opening 1015 of the outer member 1010 and/or to deploy the anchor member 310 a and/or cap member 310 b. For example, once a distal end of the outer member 1010 has advanced through a lumen opening into a lumen, the intermediate member 1020 may be advanced in a distal direction relative to the outer member 1010 to deploy the anchor member 310 a from the distal end of the outer member 1010 and/or into the lumen.
  • [0044]
    In one embodiment, the intermediate member 1020 may be configured to limit its range of movement in order to reduce instances of inadvertent deployment of the cap member 310 b within the lumen. For example, the distance that the proximal end of the intermediate member 1020 extends beyond the proximal end of the outer member 1010 may be equal to the distance necessary to deploy the anchor member 310 a. In a further embodiment, the intermediate member 1020 may be configured to limit further distal movement of the intermediate member 1020 relative to the outer member 1010 once the relative movement necessary to deploy only the anchor member 310 a has been achieved. For example, the proximal end of the intermediate member 1020 may include one or more flanges at its proximal end configured to abut the proximal end of the outer member once the relative movement necessary to deploy only the anchor member 310 a has been achieved.
  • [0045]
    The inner member 1030 may pass through the intermediate member 1020 and/or outer member 1010 and extend out the distal and/or proximal ends of the outer member 1010 and/or intermediate member 1020, respectively. In one embodiment, the distal end of the inner member 1030 may be configured to at least partially close the distal opening 1015 in the outer member 1010 in order to reduce instances of premature and/or inadvertent deployment of the closure device 300. In a further embodiment, the inner member 1030 may include an inner lumen. For example, the inner lumen of the inner member 1030 may operate as a guidewire lumen, such that the closure system 1000 may advance over a guidewire into a body lumen through an opening in the body lumen wall. As explained above, the elongate member 320 of the closure device 300 may also be at least partially disposed through the inner member 1030. In addition, the inner member 1030 may be configured to operate as and/or include a marker port and/or a flow back lumen, such as blood mark race and/or bleed back lumen, to indicate when the distal end of the closure system 1000 has entered the body lumen.
  • [0046]
    Reference is now made to FIG. 3B, which illustrates an additional example closure system 1000′ in accordance with an implementation of the present invention. The closure system 1000′ of this configuration may be functionally similar to the example closure system 1000 previously described above and shown in FIG. 3A in most respects, wherein certain features will not be described in relation to this configuration where those components may function in the manner as described above and are hereby incorporated into this additional configuration described below. Like structures and/or components may be given like reference numerals.
  • [0047]
    In particular, the closure system 1000′ may differ from the closure system 1000 of FIG. 3A by integrating the intermediate member 1020 and inner member 1030 into a single component, namely intermediate member 1020′. For example, the intermediate member 1020′ may include a proximal portion 1020 a′ and a distal portion 1020 b′. In one implementation, the proximal portion 1020 a′ may have a larger diameter than the distal portion 1020 b′. The anchor member 310 a′ and/or cap member 310 b′ of the closure device may be disposed on or proximate to the distal portion 1020 b′ of the intermediate member 1020′ within the outer member 1010′ and distal of the proximal portion 1020 a′ of the intermediate member 1020′. When the intermediate member 1020′ is advanced in a distal direction, the proximal portion 1020 a′ may assist in pushing or deploying the anchor member 310 a′ and/or cap member 310 b′ through a distal opening 1015′ in the outer member 1010′. The intermediate member 1020′ may also define a lumen through which the elongate member 320′, a guidewire, or body fluid may pass. As a result, the closure system 1000′ may have less moving parts than the closure system 1000 of FIG. 3A but may, nonetheless, operate similarly to deploy the closure device 300′ to close a body lumen opening.
  • [0048]
    Reference is now made to FIG. 3C, which illustrates an additional example closure system 1000″ in accordance with an implementation of the present invention. The closure system 1000″ of this configuration may be functionally similar to the example closure systems 1000, 1000′ previously described above and shown in FIGS. 3A-3B in most respects, wherein certain features will not be described in relation to this configuration where those components may function in the manner as described above and are hereby incorporated into this additional configuration described below. Like structures and/or components may be given like reference numerals.
  • [0049]
    As shown in FIG. 3C, in addition to or in conjunction with the closure device 300″, the closure system 1000″ may include a plug 400. The plug 400 may be configured to close an opening in a body lumen or a corresponding tissue tract. The plug 400 may be disposed within the closure system 1000″ and configured for deployment proximate the body lumen opening. In particular, the plug 400 may be disposed within the closure system 1000″ on the inner member 1030″ and distal of the intermediate member 1020″. In a further implementation, the plug 400 may be disposed on the elongate member 320″ of the closure device 300″ proximal of the anchor member 310 a″ and/or cap member 310 b″. The plug 400 may comprise any material known or used for closing a body lumen opening or tissue tract, including biodegradable materials, bioerodible materials, bioabsorbable materials, bioresorbable materials, other materials, or combinations thereof. In one implementation, the plug 400 may comprise collagen and/or polyethylene glycol.
  • [0050]
    Reference is now made to FIGS. 4-11 which illustrate an example method of deploying the closure device 300 using the closure system 1000 of FIG. 3. For example, FIG. 4 illustrates that the closure system 1000 may be advanced through a tissue tract and at least partially into a body lumen through a lumen opening to be obstructed or closed. As shown, the closure system 1000 may be advanced into the lumen over a guidewire 1040. In particular, the guidewire may pass through the inner member 1030 of the closure system 1000. The inner member 1030 may include and/or operate as a fluid mark race and/or flow back lumen in order to indicate to a user that the distal end of the closure system 1000 has entered the body lumen. For example, the closure system 1000 may be advanced in an artery, until a pulsatile blood mark is indicated at the proximal end of the inner member 1030.
  • [0051]
    Once the closure system 1000 is in position with the distal end thereof disposed within the lumen, the inner member 1030 and/or guidewire 1040 may be retracted as illustrated in FIG. 5. In particular, the inner member 1030 may be removed by pulling on the inner member 1030 while stabilizing the remaining components of the closure system 1000. In one embodiment, removing the inner member 1030 from the closure system 1000 may facilitate deployment of the closure device 300 through the distal opening 1015 of the outer member 1010.
  • [0052]
    Once the inner member 1030 has been removed, the intermediate member 1020 may be advanced in a distal direction to deploy the anchor member 310 a of the closure device 300 into the lumen as illustrated in FIG. 6. In one embodiment, the anchor member 310 a, which may have been folded and/or otherwise compacted while disposed within the outer member 1010, may expand into a deployed state.
  • [0053]
    After the anchor member 310 a is deployed, the outer member 1010 may be refracted and/or the elongate member 320 of the closure device 300 may be tensioned for the anchor member 310 a to engage the distal surface of the lumen wall proximate the lumen opening as illustrated in FIG. 7. The outer member 1010 may continue to retract, and the resulting tension in the elongate member 320 caused by the secured anchor member 310 a may deploy the cap member 310 b from the distal opening 1015 of the outer member 1010 as illustrated in FIGS. 8-9. In a further embodiment, the intermediate member 1020 may be used to deploy the cap member 310 b.
  • [0054]
    Once the cap member 310 b is deployed within the tissue tract proximal of the lumen wall, it may then be advanced into apposition with the anchor member 310 a, as illustrated in FIG. 10, in order to engage the anchor member 310 a and/or cap member 310 b with opposing surfaces of the lumen wall. During this process, the position of the anchor member 310 a may be retained by maintaining tension in the elongate member 320 as the outer member 1010 is withdrawn and/or as the cap member 310 b is advanced. In a further embodiment, a knot and/or cleat 330 may be advanced along the elongate member 320 of the closure device 300 and/or secure the cap member 310 b against the anchor member 310 a with the lumen wall sandwiched at least partially therebetween, thereby further securing the closure members in place. In a further embodiment, the elongate member 320 may include a plurality of projections (i.e., 125, FIG. 1) extending from a surface thereof and configured to secure the cap member 310 b in place and prevent proximal movement of the cap member 310 b relative to the elongate member 320. Once the cap member 310 b and anchor member 310 a are secured, the elongate member 320 may be trimmed proximal of the cap member 310 b, such as by using a suture trimmer 340, and then retracted, as shown in FIG. 11. In a further embodiment, one or more additional locking mechanisms as disclosed in more detail herein may be used to secure the cap member 310 b and/or anchor member 310 a in place.
  • [0055]
    Once deployed, the cap member 310 b and the anchor member 310 a can close or substantially close an opening in a body lumen. The vessel or tissue adjacent the opening can be disposed at least partially between the cap member 310 b and the anchor member 310 a. As the cap member 310 b is advanced, the cap member 310 b and the anchor member 310 a can apply pressure to the tissue or vessel to hold the tissue in place and close the opening. Further, the cap member 310 b and the anchor member 310 a may be configured to also bond or become connected to the tissue to further close the opening. Also, the cap member 310 b and the anchor member 310 a may slightly deform as tension is applied to accommodate the tissue that is between the cap member 310 b and the anchor member 310 a.
  • [0056]
    The embodiments of the present disclosure may be embodied in other specific forms without departing from its spirit or essential characteristics. The described embodiments are to be considered in all respects only as illustrative and not restrictive. The scope of the disclosure is, therefore, indicated by the appended claims rather than by the foregoing description. All changes which come within the meaning and range of equivalency of the claims are to be embraced within their scope.
Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US1088393 *Sep 20, 1913Feb 24, 1914Oscar E BackusButton.
US1331401 *Sep 12, 1919Feb 17, 1920Clay Summers HenryButton-fastening
US1480935 *Apr 3, 1922Jan 15, 1924Gleason Dora PBarrette
US2583625 *Oct 29, 1946Jan 29, 1952Thomas & Betts CorpMethod of and tool for crimping tubes
US2969867 *Jan 16, 1957Jan 31, 1961Filper CorpFruit transfer apparatus
US3015403 *Apr 8, 1959Jan 2, 1962American Thermos Products CompThreaded stopper expanding pouring lip combination for vacuum bottle
US3120230 *Oct 24, 1960Feb 4, 1964Jack H SandersSurgical clamp
US3494533 *Oct 10, 1966Feb 10, 1970United States Surgical CorpSurgical stapler for stitching body organs
US3939820 *Oct 29, 1974Feb 24, 1976Datascope CorporationSingle-chamber, multi-section balloon for cardiac assistance
US4007743 *Oct 20, 1975Feb 15, 1977American Hospital Supply CorporationOpening mechanism for umbrella-like intravascular shunt defect closure device
US4189808 *Sep 20, 1978Feb 26, 1980Brown Theodore GRetainer and closure for a garbage can liner bag
US4368736 *Nov 17, 1980Jan 18, 1983Kaster Robert LAnastomotic fitting
US4428376 *Jun 14, 1982Jan 31, 1984Ethicon Inc.Plastic surgical staple
US4635634 *Jul 12, 1985Jan 13, 1987Santos Manuel VSurgical clip applicator system
US4719917 *Feb 17, 1987Jan 19, 1988Minnesota Mining And Manufacturing CompanySurgical staple
US4724840 *Feb 3, 1982Feb 16, 1988Ethicon, Inc.Surgical fastener applier with rotatable front housing and laterally extending curved needle for guiding a flexible pusher
US4890612 *May 16, 1988Jan 2, 1990Kensey Nash CorporationDevice for sealing percutaneous puncture in a vessel
US4902508 *Jul 11, 1988Feb 20, 1990Purdue Research FoundationTissue graft composition
US4983176 *Mar 6, 1989Jan 8, 1991University Of New MexicoDeformable plastic surgical clip
US5078731 *Jun 5, 1990Jan 7, 1992Hayhurst John OSuture clip
US5176648 *Dec 13, 1991Jan 5, 1993Unisurge, Inc.Introducer assembly and instrument for use therewith
US5275616 *Dec 18, 1992Jan 4, 1994Quinton Instrument CompanyInsertion assembly and method of inserting a vessel plug into the body of a patient
US5281422 *Sep 24, 1991Jan 25, 1994Purdue Research FoundationGraft for promoting autogenous tissue growth
US5282808 *Feb 4, 1993Feb 1, 1994Origin Medsystems, Inc.Closure prevention apparatus for surgical clip applier
US5282827 *Mar 5, 1992Feb 1, 1994Kensey Nash CorporationHemostatic puncture closure system and method of use
US5383896 *May 25, 1993Jan 24, 1995Gershony; GaryVascular sealing device
US5383897 *Dec 10, 1993Jan 24, 1995Shadyside HospitalMethod and apparatus for closing blood vessel punctures
US5392978 *Oct 15, 1993Feb 28, 1995United States Surgical CorporationSurgical staple and endoscopic stapler
US5486195 *Jul 26, 1993Jan 23, 1996Myers; GeneMethod and apparatus for arteriotomy closure
US5591205 *Jun 6, 1995Jan 7, 1997Quinton Instrument CompanyInsertion assembly and method of inserting a vessel plug into the body of a patient
US5593412 *May 2, 1995Jan 14, 1997Cordis CorporationStent delivery method and apparatus
US5601602 *Nov 16, 1994Feb 11, 1997Quinton Instrument CompanyInsertion assembly and method of inserting a vessel plug into the body of a patient
US5709224 *Jun 7, 1995Jan 20, 1998Radiotherapeutics CorporationMethod and device for permanent vessel occlusion
US5713899 *Apr 26, 1996Feb 3, 1998Societe Jbs SaCervical cage designed for the performance of intersomatic arthrodesis
US5715987 *May 2, 1996Feb 10, 1998Tracor IncorporatedConstant width, adjustable grip, staple apparatus and method
US5716375 *Feb 21, 1996Feb 10, 1998Quinton Instrument CompanyInsertion assembly and method of inserting a vessel plug into the body of a patient
US5720755 *Oct 2, 1995Feb 24, 1998Dakov; PepiTubular suturing device and methods of use
US5855312 *Jul 25, 1996Jan 5, 1999Toledano; HavivFlexible annular stapler for closed surgery of hollow organs
US5858082 *Sep 15, 1997Jan 12, 1999Cruz; Hector GonzaloSelf-interlocking reinforcement fibers
US5860991 *Aug 22, 1997Jan 19, 1999Perclose, Inc.Method for the percutaneous suturing of a vascular puncture site
US5861003 *Oct 23, 1996Jan 19, 1999The Cleveland Clinic FoundationApparatus and method for occluding a defect or aperture within body surface
US5861005 *Feb 11, 1997Jan 19, 1999X-Site, L.L.C.Arterial stapling device
US5868755 *Jan 16, 1997Feb 9, 1999Atrion Medical Products, Inc.Sheath retractor mechanism and method
US5868762 *Sep 25, 1997Feb 9, 1999Sub-Q, Inc.Percutaneous hemostatic suturing device and method
US5868763 *Sep 16, 1996Feb 9, 1999Guidant CorporationMeans and methods for performing an anastomosis
US5871474 *Apr 2, 1997Feb 16, 1999General Surgical Innovations, Inc.Screw-type skin seal with inflatable membrane
US5871501 *Jan 12, 1998Feb 16, 1999Datascope Investment Corp.Guide wire with releasable barb anchor
US5871525 *Oct 23, 1995Feb 16, 1999Ep Technologies, Inc.Steerable ablation catheter system
US5873876 *May 5, 1998Feb 23, 1999Christy; William J.Surgical loop delivery device and method
US5873891 *Oct 7, 1997Feb 23, 1999Influence Medical Technologies, Ltd.Staple and thread assembly particularly for use in power-driven staplers for medical suturing
US6010517 *Apr 8, 1997Jan 4, 2000Baccaro; Jorge AlbertoDevice for occluding abnormal vessel communications
US6013084 *Jun 20, 1997Jan 11, 2000Target Therapeutics, Inc.Stretch resistant vaso-occlusive coils (II)
US6015815 *Sep 24, 1998Jan 18, 2000Abbott LaboratoriesTetrazole-containing rapamycin analogs with shortened half-lives
US6019779 *Oct 9, 1998Feb 1, 2000Intratherapeutics Inc.Multi-filar coil medical stent
US6022372 *Oct 14, 1998Feb 8, 2000X-Site, L.L.C.Arterial stapling device
US6024750 *Aug 14, 1997Feb 15, 2000United States SurgicalUltrasonic curved blade
US6171277 *Aug 7, 1998Jan 9, 2001Cordis Webster, Inc.Bi-directional control handle for steerable catheter
US6171329 *Aug 28, 1998Jan 9, 2001Gore Enterprise Holdings, Inc.Self-expanding defect closure device and method of making and using
US6174322 *Jul 31, 1998Jan 16, 2001Cardia, Inc.Occlusion device for the closure of a physical anomaly such as a vascular aperture or an aperture in a septum
US6179849 *Jun 10, 1999Jan 30, 2001Vascular Innovations, Inc.Sutureless closure for connecting a bypass graft to a target vessel
US6179860 *Aug 18, 1999Jan 30, 2001Artemis Medical, Inc.Target tissue localization device and method
US6334865 *Jul 27, 1999Jan 1, 2002Fusion Medical Technologies, Inc.Percutaneous tissue track closure assembly and method
US6506210 *Sep 11, 2000Jan 14, 2003Angiolink CorporationWound site management and wound closure device
US6508828 *Nov 3, 2000Jan 21, 2003Radi Medical Systems AbSealing device and wound closure device
US6626919 *Jul 21, 1998Sep 30, 2003Lee L. SwanstromMethod and apparatus for attaching or locking an implant to an anatomic vessel or hollow organ wall
US6673083 *Oct 11, 2000Jan 6, 2004General Surgical Innovations, Inc.Method for blood vessel clip application
US6676671 *Mar 2, 2001Jan 13, 2004United States SurgicalStapling apparatus and method for heart valve replacement
US6676685 *Jun 18, 2001Jan 13, 2004Tyco Healthcare Group LpArterial hole closure apparatus
US6679904 *Oct 15, 1997Jan 20, 2004Malachy GleesonDevice for closure of puncture wound
US6685707 *Sep 25, 2002Feb 3, 2004Walter Lorenz Surgical, Inc.Cranial clamp and method for fixating a bone plate
US6837893 *Aug 31, 2001Jan 4, 2005Onux Medical, Inc.Multi-fastener surgical apparatus and method
US6837906 *Jan 2, 2004Jan 4, 2005Ensure Medical, Inc.Lung assist apparatus and methods for use
US6846319 *Dec 14, 2000Jan 25, 2005Core Medical, Inc.Devices for sealing openings through tissue and apparatus and methods for delivering them
US6984238 *Apr 23, 2004Jan 10, 2006Gifford Iii Hanson SDevices and methods for performing avascular anastomosis
US6989003 *Aug 31, 2001Jan 24, 2006Conmed CorporationObturator and cannula for a trocar adapted for ease of insertion and removal
US6989016 *Oct 20, 2003Jan 24, 2006Medtronic Angiolink, Inc.Vascular suction cannula, dilator and surgical stapler
US7163551 *Aug 8, 2002Jan 16, 2007Thomas AnthonySurgical stapling device
US7169158 *Oct 18, 2001Jan 30, 2007Tyco Healthcare Group LpAnastomosis instrument and method for performing same
US7169164 *Sep 21, 2001Jan 30, 2007Atritech, Inc.Apparatus for implanting devices in atrial appendages
US7316704 *Mar 22, 2004Jan 8, 2008Accessclosure, Inc.Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture
US7316706 *Jun 14, 2004Jan 8, 2008Medtronic Vascular, Inc.Tensioning device, system, and method for treating mitral valve regurgitation
US7322995 *Sep 15, 2003Jan 29, 2008Damage Control Surgical Technologies, Inc.Method and apparatus for vascular and visceral clipping
US7645285 *May 26, 2004Jan 12, 2010Idx Medical, LtdApparatus and methods for occluding a hollow anatomical structure
US7867249 *Aug 8, 2003Jan 11, 2011Integrated Vascular Systems, Inc.Clip applier and methods of use
US8103327 *Jan 24, 2012Rhythmia Medical, Inc.Cardiac mapping catheter
US8105352 *Dec 14, 2005Jan 31, 2012Radi Medical Systems AbMedical sealing device
US20020183787 *Jun 1, 2001Dec 5, 2002Velocimed, L.L.C.Closure devices, related delivery methods and tools, and related methods of use
US20020198562 *Apr 18, 2002Dec 26, 2002Radi Medical Systems AbReinforced absorbable medical sealing device
US20030004543 *Oct 15, 1997Jan 2, 2003Malachy GleesonDevice for closure of puncture wound
US20030009180 *Jun 5, 2002Jan 9, 2003Hinchliffe Peter W.J.Vascular hole closure device
US20030018358 *Jul 3, 2002Jan 23, 2003Vahid SaadatApparatus and methods for treating tissue
US20030023248 *Mar 15, 2002Jan 30, 2003Parodi Juan C.Systems and methods for applying a suture within a blood vesel lumen
US20030060846 *Jun 14, 2002Mar 27, 2003Radi Medical Systems AbTamping mechanism
US20030093108 *Nov 15, 2002May 15, 2003Ernesto AvellanetAneurysm neck cover for sealing an aneurysm
US20040009205 *Jul 9, 2003Jan 15, 2004Incept LlcMethods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US20040009289 *Jul 9, 2003Jan 15, 2004Carley Michael T.Closure device and methods for making and using them
US20050203552 *Mar 11, 2004Sep 15, 2005Laufer Michael D.Surgical fastening system
US20070005093 *Jul 1, 2005Jan 4, 2007Cox John ASystem for tissue dissection and retraction
US20070010853 *Sep 15, 2006Jan 11, 2007Integrated Vascular Systems, Inc.Apparatus and methods for positioning a vascular sheath
US20070010854 *Sep 18, 2006Jan 11, 2007Christy CumminsSurgical Staple
US20070021778 *Jun 19, 2006Jan 25, 2007Abbott Laboratories Abbott Vascular DevicesApparatus and method for delivering a closure element
US20070185530 *Sep 1, 2006Aug 9, 2007Chao Chin-ChenPatent foramen ovale closure method
US20080004636 *Jun 28, 2006Jan 3, 2008Abbott LaboratoriesClip applier and methods of use
US20080004640 *Jun 28, 2006Jan 3, 2008Abbott LaboratoriesVessel closure device
US20080009794 *Apr 22, 2005Jan 10, 2008Accessclosure, Inc.Apparatus and method for temporary hemostasis
US20080091235 *Oct 9, 2007Apr 17, 2008Sirota Daniel JClosure device with biomaterial patches
US20080243182 *Jan 22, 2008Oct 2, 2008Datascope Investment Corp.Vascular hemostasis device and deployment apparatus
US20100042144 *Jul 29, 2009Feb 18, 2010Steven BennettMedical Device for Wound Closure and Method of Use
US20130006274 *Jan 3, 2013Abbott LaboratoriesClip applier and methods of use
USRE34866 *Dec 31, 1991Feb 21, 1995Kensey Nash CorporationDevice for sealing percutaneous puncture in a vessel
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US7879071May 9, 2003Feb 1, 2011Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US7887555Jul 9, 2003Feb 15, 2011Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US7901428Mar 8, 2011Integrated Vascular Systems, Inc.Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US7918873Sep 18, 2006Apr 5, 2011Abbott Vascular Inc.Surgical staple
US7931669Apr 26, 2011Integrated Vascular Systems, Inc.Integrated vascular device with puncture site closure component and sealant and methods of use
US8007512Aug 30, 2011Integrated Vascular Systems, Inc.Plunger apparatus and methods for delivering a closure device
US8128644Sep 19, 2003Mar 6, 2012Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US8182497May 22, 2012Integrated Vascular Systems, Inc.Closure device
US8192459Jun 5, 2012Abbott Vascular Inc.Blood vessel closure clip and delivery device
US8202283Jun 19, 2012Integrated Vascular Systems, Inc.Methods for manufacturing a clip and clip
US8202293Jun 20, 2008Jun 19, 2012Integrated Vascular Systems, Inc.Clip applier and methods of use
US8202294Dec 20, 2010Jun 19, 2012Integrated Vascular Systems, Inc.Clip applier and methods of use
US8226681Jul 24, 2012Abbott LaboratoriesMethods, devices, and apparatus for managing access through tissue
US8236026Aug 7, 2012Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US8257390Sep 4, 2012Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US8303624Mar 15, 2010Nov 6, 2012Abbott Cardiovascular Systems, Inc.Bioabsorbable plug
US8313497Nov 20, 2012Abbott LaboratoriesClip applier and methods of use
US8323312Jun 9, 2009Dec 4, 2012Abbott LaboratoriesClosure device
US8398656Mar 2, 2011Mar 19, 2013Integrated Vascular Systems, Inc.Clip applier and methods of use
US8398676Mar 19, 2013Abbott Vascular Inc.Closure device
US8469995Jun 4, 2012Jun 25, 2013Abbott Vascular Inc.Blood vessel closure clip and delivery device
US8486092Mar 11, 2009Jul 16, 2013Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US8486108Feb 1, 2006Jul 16, 2013Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US8518057Sep 13, 2012Aug 27, 2013Abbott LaboratoriesClip applier and methods of use
US8529587Jun 6, 2012Sep 10, 2013Integrated Vascular Systems, Inc.Methods of use of a clip applier
US8556930Jun 28, 2006Oct 15, 2013Abbott LaboratoriesVessel closure device
US8579932Feb 24, 2004Nov 12, 2013Integrated Vascular Systems, Inc.Sheath apparatus and methods for delivering a closure device
US8585836Jun 18, 2012Nov 19, 2013Integrated Vascular Systems, Inc.Methods for manufacturing a clip and clip
US8590760May 24, 2005Nov 26, 2013Abbott Vascular Inc.Surgical stapler
US8597325Nov 29, 2010Dec 3, 2013Integrated Vascular Systems, Inc.Apparatus and methods for providing tactile feedback while delivering a closure device
US8603116Aug 4, 2010Dec 10, 2013Abbott Cardiovascular Systems, Inc.Closure device with long tines
US8603136May 3, 2007Dec 10, 2013Integrated Vascular Systems, Inc.Apparatus and methods for providing tactile feedback while delivering a closure device
US8657852Mar 8, 2013Feb 25, 2014Abbott Vascular Inc.Closure device
US8672953Jun 6, 2011Mar 18, 2014Abbott LaboratoriesTissue closure system and methods of use
US8690910Mar 31, 2006Apr 8, 2014Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US8728119Feb 18, 2011May 20, 2014Abbott Vascular Inc.Surgical staple
US8758396Apr 27, 2006Jun 24, 2014Integrated Vascular Systems, Inc.Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US8758398Sep 7, 2007Jun 24, 2014Integrated Vascular Systems, Inc.Apparatus and method for delivering a closure element
US8758399Aug 2, 2010Jun 24, 2014Abbott Cardiovascular Systems, Inc.Expandable bioabsorbable plug apparatus and method
US8758400Nov 8, 2010Jun 24, 2014Integrated Vascular Systems, Inc.Closure system and methods of use
US8784447Apr 25, 2005Jul 22, 2014Abbott Vascular Inc.Surgical stapler
US8808310Feb 14, 2007Aug 19, 2014Integrated Vascular Systems, Inc.Resettable clip applier and reset tools
US8820602Nov 19, 2010Sep 2, 2014Abbott LaboratoriesModular clip applier
US8821534Dec 6, 2010Sep 2, 2014Integrated Vascular Systems, Inc.Clip applier having improved hemostasis and methods of use
US8858594Dec 18, 2009Oct 14, 2014Abbott LaboratoriesCurved closure device
US8893947Dec 17, 2007Nov 25, 2014Abbott LaboratoriesClip applier and methods of use
US8905937Feb 26, 2009Dec 9, 2014Integrated Vascular Systems, Inc.Methods and apparatus for locating a surface of a body lumen
US8920442Aug 23, 2006Dec 30, 2014Abbott Vascular Inc.Vascular opening edge eversion methods and apparatuses
US8926633Jun 19, 2006Jan 6, 2015Abbott LaboratoriesApparatus and method for delivering a closure element
US8926656Jan 10, 2011Jan 6, 2015Integated Vascular Systems, Inc.Clip applier and methods of use
US8956388Apr 21, 2008Feb 17, 2015Integrated Vascular Systems, Inc.Integrated vascular device with puncture site closure component and sealant
US9050068May 20, 2013Jun 9, 2015Abbott LaboratoriesClip applier and methods of use
US9050087May 14, 2008Jun 9, 2015Integrated Vascular Systems, Inc.Integrated vascular device with puncture site closure component and sealant and methods of use
US9060769May 1, 2008Jun 23, 2015Abbott Vascular Inc.Surgical stapler
US9089311Jan 8, 2010Jul 28, 2015Abbott Vascular Inc.Vessel closure devices and methods
US9089674Sep 15, 2006Jul 28, 2015Integrated Vascular Systems, Inc.Apparatus and methods for positioning a vascular sheath
US9131932 *Feb 1, 2013Sep 15, 2015St. Jude Medical Puerto Rico LlcDual lumen carrier tube with retractable sleeve and methods
US9131941Jun 15, 2012Sep 15, 2015Curaseal Inc.Fistula treatment devices and methods
US9149276Mar 21, 2011Oct 6, 2015Abbott Cardiovascular Systems, Inc.Clip and deployment apparatus for tissue closure
US9173644Jan 8, 2010Nov 3, 2015Abbott Vascular Inc.Closure devices, systems, and methods
US9211116Jun 15, 2012Dec 15, 2015Curaseal Inc.Fistula treatment devices and related methods
US9241696Oct 29, 2009Jan 26, 2016Abbott Vascular Inc.Closure device
US9271707Mar 8, 2013Mar 1, 2016Integrated Vascular Systems, Inc.Clip applier and methods of use
US9282965May 16, 2008Mar 15, 2016Abbott LaboratoriesApparatus and methods for engaging tissue
US9295469Jun 3, 2013Mar 29, 2016Abbott Vascular Inc.Blood vessel closure clip and delivery device
US9314230Aug 22, 2014Apr 19, 2016Abbott Vascular Inc.Closure device with rapidly eroding anchor
US9320522Aug 31, 2011Apr 26, 2016Integrated Vascular Systems, Inc.Closure device and methods for making and using them
US9332976Nov 30, 2011May 10, 2016Abbott Cardiovascular Systems, Inc.Tissue closure device
US9364209Dec 21, 2012Jun 14, 2016Abbott Cardiovascular Systems, Inc.Articulating suturing device
US20130123844 *May 16, 2013St. Jude Medical Puerto Rico LlcLarge bore closure device with inner and outer seals
US20140222064 *Feb 1, 2013Aug 7, 2014St. Jude Medical Puerto Rico LlcDual lumen carrier tube with retractable sleeve and methods
EP2720625A2 *Jun 15, 2012Apr 23, 2014Curaseal Inc.Fistula treatment devices and related methods
EP2720625A4 *Jun 15, 2012Feb 18, 2015Curaseal IncFistula treatment devices and related methods
WO2012047815A2 *Oct 3, 2011Apr 12, 2012The Johns Hopkins UniversityMethod and device for closure of intraluminal perforations
WO2012047815A3 *Oct 3, 2011Jun 14, 2012The Johns Hopkins UniversityMethod and device for closure of intraluminal perforations
WO2012174469A2Jun 15, 2012Dec 20, 2012Curaseal Inc.Fistula treatment devices and related methods
Classifications
U.S. Classification606/213
International ClassificationA61B17/03
Cooperative ClassificationA61B2017/00646, A61B17/0057, A61B2017/00654
European ClassificationA61B17/00P
Legal Events
DateCodeEventDescription
Jul 3, 2014ASAssignment
Owner name: ABBOTT VASCULAR INC, CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:FORTSON, AARON M.;ROORDA, WOUTER E.;REEL/FRAME:033242/0001
Effective date: 20100114