|Publication number||US2127903 A|
|Publication date||Aug 23, 1938|
|Filing date||May 5, 1936|
|Priority date||May 5, 1936|
|Publication number||US 2127903 A, US 2127903A, US-A-2127903, US2127903 A, US2127903A|
|Original Assignee||Davis & Geck Inc|
|Export Citation||BiBTeX, EndNote, RefMan|
|Referenced by (336), Classifications (10) |
|External Links: USPTO, USPTO Assignment, Espacenet|
Tube for surgical purposes and method of preparing and using the same
US 2127903 A
Aug. 23, 1938. A. BOWEN 2,127,903
TUBE FOR SURGICAL PURPOSES AND METHOD OF PREPARING AND USING THE SAME Filed May 5', 1936 4 Sheets-Sheet l v YINIVENTOR.
A. BOWEN 2,127,903 TUBE FOR SURGICAL PURPOSES AND METHOD OF PREPARING-AND USING THE SAME Aug. 23, 1938.
Filed May 5, 19356 4 Sheets-Sheet 2 INVENTOR.
2497 40? EOW'F/V,
Aug. 23, 1938. A. BOWEN 2,127,903 T UBE FOR SURGICAL PURPOSES AND METHOD OF PREPARING AND usme THE SAME Filed y 5, 1956 4 Sheets-Sheet 5 COMMON 5/4 E j J/ .FJZ, g f
I flfrbla? goplglfxifl. BY
A. BOWEN Filed May 5, 1956 4 Sheets-Sheet 4 INVENTOR. @7770? EQWf/V,
Patented Aug. 23, I
UNITED STATES PATENT OFFICE TUBE FOB SURGICAL PURPOSES lgl'ETHOD OF PREPARING USING THE Arthur Bowen, Los Angeles, Calif., assignor at Davis & Geek, Inc., Brooklyn, N. Y., a corporation of New York Application May 5, 1936, Serlal No. 17,930
- 10 Claims. (01. 128-334) The present invention relates to a tube of may be put may be readily separated into five absorbable animal material, a method of prepartypes of situations as follows:
ing the same and its use in surgery. 1. End to end, end to side, or side ,to side The principal object of the invention is to proanastomosis;
vide a hollow tube ofabsorbable animal tissue 2. Transplantation of one duct into another:
having requisite rigidity and absorptive properties 3. Structural support for reconstruction or rewlth minimum tendency to cause irritation of pair:
animal. tissue, to devise methods whereby the same 4. Used as an exterior sheath to protect a transmaybe readily prepared and to propose various planted nerve, tendon or the like;
uses and. practical applications thereof for 5. Used for drainage purposes, with or without surgical purposes. wicks.
As long ago as 1774, Leconte advocated wrap- The invention further consistsin the novel conping a section of a goose quill around a wounded structlon, arrangement'and combination of parts, blood vessel holding it in place with a ligature. methods of manufacture and use more fully l tr Later Latteri and Petrinari reported the use of inafter described in the drawings. 15
implanted magnesium tubes and quills of doves In the-drawings: feathers for end to end anastomosisof the severed F 1 s ws 8 completed tube of this n conimon bile duct using-such tubes and quills. t nl Today the use of Murphy buttons for end to and Fig. 2 shows a modified form of tube with de- 2 anastomosis of the severed or strictured intestinal pressions in its end portions; tract is well known. Difiiculties are encountered Fig. 3 shows a collared bobbin; in these situations in that after the parts have Fig. 4 is a modified bobbin or tube with collars, healed, the non-absorbable tubes, or buttons must at'each end; be removed, accomplished usually by dislodgment Fig. 5 shows a spool-shaped tube or bobbin;
and subsequent passage out of the system by the Fig. 6 illustrates a di-conical shaped tube; 25
patient. Fig. 7 shows a completed Y-tube;
The present invention seeks to avoid the Fig. 7a illustrates a completed T-tube; necessity of removal of such tubes by constructing Fig. 8 shows the method of wrapping tapes on them of a material which will be readily absorbed a mandrel in the manufacture of a tube prior to or digested by the body during or subsequent to form pressing where that is desirable:
the repair period. Fig. 9 shows a tube in the process of being To this end, the invention contemplates in -its formed from cords; broadest aspect straight, angular, curved, Y or Fig. 10 shows a tube in the process of being T tubes of absorbable animal tissue such, for inmanufactured from woven strands;
.35 stance, as the submucosa layer of animal in- Fig. 11 is a composite view of a two-part testinal tissue. mandrel for the manuiacture of T-tubes;
The invention further contemplates the manu- Fig. 12 shows the manner of winding a tape on feature of such tubes by forming the animal tissue the T-shaped mandrel of Fig. 11;
into a tube. This may be done by wrapping, Fig. 120. shows the completely wound strip on winding, spinning or forming the tissue over a the T-mandrel; mandrelor core, form pressing the tissue to shape Figs. 13, 14 and 15 progressively illustrate a and subsequently removing the core. For this tube implantation in an end to end anastomosis purpose, the animal tissue may be in the form of using a T-tube. threads, ribbons or a pulp to which a binder such Fig. 16 illustrates a method of imp a as glue has been added so that upon formation straight tube in an end to end anastomosis; 45 of the material into a tube. the material will Fi 1'1 i us es a -tube implantation in a harden in that shape and maintain its form. end to side anastomosis;
\ The invention I further contemplates the use i 18 illustrates t P p r implantaof such tubes as above described in a large numtion oi. the common duct into the duodenum; bar of practical applications and for surgical pur-' Fig. ,19 shows this Operation complete except 50 poses. While-a number oi uses have been set forth for suturing;
herein, it is to be understood that they are men-,- Fig. 20 illustrates a side to side anastomosis;
tioned as illustrative and typical only and are not Fig. 21 illustrates a severed nerve about to have to beconstrued in a limiting sense. its edges approximated; 5 Perhaps the use to which tubes or character ,Figs, 21a, 21b and 210 show the method of is the submucous layer of --animal intestinal recited for that approximating the edges of a severed nerve and its protection by an absorbable tube.
Referring'now with particularity to the drawings, in Fig. 1 there is shown perhaps the most common type of tube or bobbin, to wit: a straight, hollow element of elongated nature, the dimensions of such an article being variable, of course, dependent upon the situation in which it is to be used. The words tube" and bobbin are herein" used interchangeably as their difference relates only to dimensions. A short, stubby tube may be termed a bobbin.
In Fig. 2, a modified form of tube is shown at I having a slightly depressed groove 3 at the end portion thereof. This form is particularly desirable in an end to end anastomosis in that it facilitates ligaturing the incised ends of the duct.
In Fig. 3, a tube is shown at I having a collar 5 at one end which may be desirable in some instances.
In Fig. 4, the tube 4 and 8 at each end.
In Fig. 5, a spool shaped tube! is shown' which involves all of the desirable attributes of the tube of Fig. 2 in that ligaturing is facilitated.
The spool shape of the tube may be further accentuated into the form shown in Fig. 6 where at 8 the tube is diconical in shape, that is, it consists essentially of two frustro-conical configurations with their smaller bases contiguous.
In Figs. 7 and 7a, Y and T shaped tubes are shown respectively.
In manufacturing these shapes, anysuitable absorbable animal material may be utilized which will have or can be made to have desirable rigidity, absorbabiiity and freedom from a tendency to produce tissue irritation. The material must likewise be capable of withstanding heat or chemical sterilization. The best material of which I am aware from which these tubes may be made is provided with collars I tissue.
This material in either the form of threads or wound over a metal or other form to give it the desired shape. For instance in Fig. 8 a ribbon 9 may be spirally wound over a metal form i0, slightly overlapping the convolutions, and the core I! subsequently removed after the ribbon has been permitted to assume a self-sustaining condition.
In Fig. 9, threads ii are spirally wound, woven or spun over the core ill in the same manner as of Fig. 8. It has been foundthat manufacturethe contact of the in this type of threads with each other is suiiicient to cause a coalescence therebetween with the result that an eventually integral construction results.
In Fig. 10, a modified form of weaving is shown over the core III, where these strands may be either in the form of threads or ribbons.
Where T or Y tubes are to be made, it will be desirable to provide a two-part core such, for instance, as is shownin Fig. 11. There one armis shown at i! having a threaded socket II in.
which the leg ll may be screwed. Obviously where a Y tubeis desired instead of a T, the arm I! may assume a V shape. In manufacturing a T tube from the two-part core of Fig. 11, reference is had to. Figs. 12 and 12a using preferably a ribbon material, such for instance, as is shown in Fig. 8. In this instance, the ribbon may be wound on the core beginning at one end of' the arm, spirally around that arm from the end toward the center. At the center, it is crissdown the leg I to the end, back again upon in itself and out to the opposite end of' the arm I2. -Where desired, a second or any number of additional layers may be superimposed in the same manner and beginning at the opposite end of the arm it. when the winding has been completed and the material is self-sustaining, the core may be disconnected by unscrewing the leg I from the arm I! followed by subsequent removal of the latter.
Obviously, absorbable straight, Y or T tubes of anmial tissue may be made also by winding or spinning gut threads or narrow gut ribbons or strips spirally or transversely over a form and held together by a binder of glue or similar substance.
In all cases, it is desirable to form press the material oi the tubes or bobbins to shape, either with or without heat as this materially assists in bringing the tube to 'a self-sustaining condition with smooth surfaces. This action, therefore, eliminates to a great extent the irregularities in the surface oi the articles shown, for instance, in Figs. 8, 9, 10, 12 and 12d.
For the purpose of retarding absorption by animal tissue, the absorbable tubes may. be further treated. The methods which I have devised for the purpose may consists of: (1) immersion of the absorbable tube in a solution of formaldehyde; (2) immersion of the tube in liquid alboline; 3) coating the tube with keratin; (4) coating the tube with paraillne; and (5) coating the tube with resinous material.
Various surgical situations in which the absorbable tubes of animal membrane which I have devisedmay be used will now be recited although it is to be distinctly understood that in the recitation of these practical applications, they are to be taken as typical only and are not to be construed as limiting the invention. The invention, on the contrary, is to be construed broadly as any use to hich the tubes of this invention may be put 1' a surgical standpoint is to be considered, as coming within thepurview of the invention.
1. End to end anastomosis of the severed or strictured common bile duct over an implanted absorbable straight tube of animal membrane or a Y or T-shap'ed tube 01' the same Figs. 13, 14 and 15 progressively illustratesuch an implantation. The two ends of the severed common bile duct are shown at II through which sutures it have been sewn. In Fig. 14, the severed ends I! have been partially approximated and at this point a 1 tube I! of the invention has been inserted in the two ends as shown in Fig. 15. The approximation of the severed ends ll of the duct is then completed further manipulation of the sutures.
2. End to end anastomosis of the hepatic duct to the common Hie duct over an implanted straight tube of absorbable animal tissue or a T-shaped tube of the same. Reference may here be had to Figs. 16 and 17. In Fig. 16, the absorbable straight tube is shown at i inserted into the ends of the common bile duct II and the hepatic duct ll. sutures ll being held by the usual forceps is. The anastomosis is completed in much the 1swan-1e1 lmanner as recited above with reference to Fig. 17 shows an absorbable to the same situation as the hepatic duct II has to the erect T-tube i! applied in Fig. m except that I been anasicmosed direct duodenum II through an lacks-:1 portion curved needles 23 ready ior implantation.
3. Transplantation oi the common bile duct to (a) duodenum, (b) stomach, (c) iejunum, (d) colon, using an implanted straight tube or 1"- shaped tube of absorbable animal tissue for direct implantation or by use of the Coilfey technique.
Fig. 18 illustrates an incision 2| made in theduodenum 20 by means of scalpel 22 and the common duct IS with sutures i6 attached and carrying 19 shows the manner of implantation of the common duct l into the duodenum 2II by means o! a straight absorbable tube I, the suturing being completed subsequently in the usual manner.
4. Tight suture of the common bile duct after exploratory choledochtomy with implantation of an absorbable tube of animalmembrane to (a) facilitate closure, (b) prevent too tight suture and stricture, (c) prevent biliary fistula.
5. The use of-an absorbable tube of animal membrane to bridge a small gap in the ends of the common or hepatic bile duct and as a structural support over which to build and reconstruct the duct with surrounding tissues.
II. Urological surgery 1. Reconstruction of the urethra with anal) j sorbable tube of animal membrane as a support-I ing tunnel. v
- 2. Reconstruction of cut, stenosed, orstrictured vas deferens.
3. Direct end t'o end anastomosis of cut or strictured ureter over the implanted absorbable tube.
The development 01' an'absorbable tube of animal membrane over which to anastomose a cut or.
strictured ureter appears to meet the requirements of (a) simple technique, (b) splintage of" the suture line, .(c) patent lumen with no inter- 1 ference with urinary flow and (d) absorption.
4. Tight suture after ureterotomy, using the implanted absorbable tube to facilitate suturing and to support the lumen of the sutured ureten.
5. Utero-intestinal anastomosis, implanting a sufllcient length of the absorbable tube in the lumen of the transplanted ureter to maintain its pateney during the period of traumatic swelling following "its having been embedded in the wall of the intestine, thereby preventing obstruction of the urinary flow and back pressure in the kidney.
6. Plastic surgery of the urethra, by implanting the absorbable 'tube as a tunnel throughwhich to maintain urinary flow and over which as a structural support to reconstruct the wall of the urethra.
III. Gynecology 1. Plastic reconstruction of a strictured lumen or fimbriated end of the Fallopiantube to. maintain pateney.
2. Reconstruction and maintenance of the inmen of the remaining end of the Fallopian tube after removal of tubal pregnancy, especially in those cases where a previous salp'ingectomy on the lymphatic ducts.
other side has been done or'where there is pathology in the other tube. In this instance, an absorbable tube of suitable diameter is inserted in the uterine endoi the tube and anchored by stay sutures; the absorbable tube being permitted to project beyond the Fallopian tube so as to prevent,
distal tubal mucosa from contracting and narrowing the distal end of the tube.
' IV. Vascular surgery I End to end anastomosis of veins, arteries, and In all previous methods, an attempt was made to splint the suture line and permit the flow of blood; but never has'an absorb- Fig.
able tubular membrane been used within or without the lumen in the suturing of blood vessels.
V. Surgery of salivary ducts Transplantation, drainage, and dilatation of strictured or severed salivary ducts.
v1. Gastro-intestinal surgery 1. Anastomosis of gallbladder to stomach-duodenum or jejunum for the purpose of maintaining patency of the lumen and permitting drainage of bile to the stomach or intestine,
2. To facilitate end to end, end to side, and side to side anastomosis of intestines over an absorbable bobbin. The advantages of the absorbable bobbin of animal tissue for these surgical situations include (a) the bobbin facilitates the placing of sutures, (b) it splints the suture line,
(0) it permits drainage of intestinal contents through a patent lumen, (d) it avoids the necessity of periormingenterostomy for decompression above sutured anastomosis, (e) the bobbin absorbs without the possibility of causing intestinal "obstruction during passage.
8. To maintain the pateney of gastro-enterostomy opening. The technic of gallbladder anastomosis is shown in Fig. 20. In that figure the gallbladder is shown at 24 anastomosed in v a side to side relationship with the stomach 25 by means of a collared absorbable tube 4. Obviously the same type .ofanastomosis may be made between the gallbladder and the duodenum.
VIIfOrtope'dic surgery In tendon suturing,,a sutured tendon may be placed in the lumen of a lubricated absorbable, .tube of animal membrane, which is split longitudinally on one side, to (a) prevent adhesions of the sutured tendon to the surrounding structures,(b) permit the tendon to lie and move in the tunnel of the absorbable tube, and (0) creation of a residual tunnel of surrounding To deposit a sutured nerve within the sheath of the absorbable tube to prevent adhesions.
Reference is here made to Fig. 21. After the ends of the cut or neuromatous nerves 26 are approximated, as in Figs. 21a. and 211), a suitable length and diameter of absorbable tube of animal membrane 21 is cut longitudinally, the edges separated and the sutured nerve placed within the lumen of the absorbable tube and the cut edges of the tube approximated with several interrupted sutures, a; few of these being left long and threaded on a needle and used to anchor the tube in place over the sutured nerve, as shown tube. 1x. Drainage tubes with 'or without wicks The use of the absorbable tubes of animal membrane as drainage tubes, with or without inF'ig. 210. In such cases, a lubricant may be interposed between the implanted organ and the 1 axially located wicks, especially in regions where 15 one would fear the loss of a non-absorbable drain, such, for example, as in brain absesses. Absorbable catgut strands have been used as wicks.
It will be obvious that in all of the above situations an absorbable tube is desirable because not only of its minimum irritating nature to animal tissues but also because it does not need to be subsequently removed from the locus, being gradually digested or absorbed by the body. By
the time the tube has disappeared by reason of the body processes, repair has taken place through growth or healing between the parts as desired. The period of time required for this complete absorption will, of course, be dependent upon previous treatment of the tube to modify its absorptiveness.
While the invention has been shown and described with particular reference to certain speciflc embodiments, it is to be understood that it is not to be limited thereto, but is to be construed broadly, and limited only by the scope of the claims. I claim: v
1. As a complete article of manufacture, a tube of absorbable animal material.
2. As a complete article of manufacture, a Y- tube of absorbable animal material.
3. As a complete article of manufacture, a T- tube of absorbable animal material.
4. A method of manufacturing a tubular article for use in surgical situations which consists in forming animal material over a mandrel to form a tube and when the tube has become selfsustaining, removing the mandrel.
5. The method of claim 4 which includes the step of form pressing the animal material on the mandrel prior to removing the latter.
6. The method of manufacturing a tubular article for use in surgical situations which consists in winding animal material spirally in one direction around a mandrel and then back in a reverse direction spirally to form a tube, and when the tube becomes self-sustaining removing the mandrel.
'7. A method of anastomosis which consists of implanting a tube of absorbable animal material into the parts to be anastomosed and permitting the tube to remain in place until absorbed.
8. A method of lending support to a hollow organ during repair and to maintain the patency of the lumen which consists in implanting therein a tube of absorbable animal material and permitting the tube to remain in place until absorbed.
9. A method of protecting an animal organ during repair which consists of implanting said organ in a tube of absorbable animal material and permitting the tube to remain in place until absorbed.
10. The method of claim 9 in which a lubricant is interposed between the implanted 'organ and the tube.
' ARTHUR BOWEN.
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US2428918 *||Sep 12, 1944||Oct 14, 1947||Grover C Miller||Anastomosis ring|
|US2451703 *||May 2, 1945||Oct 19, 1948||Weiss Paul Alfred||Resilient tantalum tubes and a process for making same|
|US2593980 *||Jul 19, 1950||Apr 22, 1952||David J Calicchio||Surgical drainage tube|
|US2615450 *||Jun 9, 1948||Oct 28, 1952||Bower John O||Suture treatment and product|
|US2900644 *||Nov 1, 1955||Aug 25, 1959||Johnson & Johnson||Heterograft material|
|US3105492 *||Oct 1, 1958||Oct 1, 1963||Us Catheter & Instr Corp||Synthetic blood vessel grafts|
|US3142067 *||Feb 16, 1961||Jul 28, 1964||William J Liebig||Synthetic vascular implants|
|US3155095 *||Feb 7, 1961||Nov 3, 1964||Brown Adolph M||Anastomosis method and means|
|US3176316 *||Jan 7, 1963||Apr 6, 1965||Bruce R Bodell||Plastic prosthetic tendon|
|US3225766 *||Mar 26, 1962||Dec 28, 1965||Grace W R & Co||Method of making absorbable surgical sutures from poly beta hydroxy acids|
|US3254651 *||Sep 12, 1962||Jun 7, 1966||Babies Hospital||Surgical anastomosis methods and devices|
|US3272204 *||Sep 22, 1965||Sep 13, 1966||Ethicon Inc||Absorbable collagen prosthetic implant with non-absorbable reinforcing strands|
|US3304557 *||Sep 28, 1965||Feb 21, 1967||Ethicon Inc||Surgical prosthesis|
|US3317924 *||May 27, 1963||May 9, 1967||Veen Harry H Le||Vascular prostheses|
|US3408659 *||Jul 21, 1965||Nov 5, 1968||Thiele Heinrich||Artificial blood vessels and process of making same|
|US3479670 *||Oct 19, 1966||Nov 25, 1969||Ethicon Inc||Tubular prosthetic implant having helical thermoplastic wrapping therearound|
|US3496939 *||Aug 9, 1967||Feb 24, 1970||Odiaga Carlos E||Surgical anastomotic sleeve coupling|
|US3620218 *||Aug 25, 1969||Nov 16, 1971||American Cyanamid Co||Cylindrical prosthetic devices of polyglycolic acid|
|US3683926 *||Jul 9, 1970||Aug 15, 1972||Dainippon Pharmaceutical Co||Tube for connecting blood vessels|
|US3786817 *||Jun 1, 1972||Jan 22, 1974||Palma J||Method and apparatus for aiding severed nerves to join|
|US3833002 *||Sep 10, 1973||Sep 3, 1974||J Palma||Apparatus for aiding severed nerves to join|
|US3924274 *||Jul 3, 1974||Dec 9, 1975||Friedrichsfeld Gmbh||An adjunct and method for facilitating implantation of joint prostheses|
|US3938528 *||Aug 23, 1973||Feb 17, 1976||Investors In Ventures, Inc.||Implanting and splicing articles and methods for living beings|
|US3948271 *||Jan 27, 1975||Apr 6, 1976||Taichiro Akiyama||Drain for the eardrum and apparatus for introducing the same|
|US3961631 *||Jun 20, 1974||Jun 8, 1976||Investors In Ventures, Inc.||Methods for applying surgical splints|
|US3988782 *||Apr 1, 1975||Nov 2, 1976||Dardik Irving I||Non-antigenic, non-thrombogenic infection-resistant grafts from umbilical cord vessels and process for preparing and using same|
|US4013078 *||Oct 7, 1975||Mar 22, 1977||Feild James Rodney||Intervertebral protector means|
|US4352358 *||Jun 30, 1981||Oct 5, 1982||Angelchik Jean P||Apparatus for effecting anastomotic procedures|
|US4400833 *||Jun 10, 1981||Aug 30, 1983||Kurland Kenneth Z||Means and method of implanting bioprosthetics|
|US4469101 *||Jun 7, 1982||Sep 4, 1984||Battelle Memorial Institute||Suture device|
|US4516584 *||Jan 7, 1983||May 14, 1985||Cordis Corporation||Suture collar|
|US4546499 *||Dec 13, 1982||Oct 15, 1985||Possis Medical, Inc.||Method of supplying blood to blood receiving vessels|
|US4562597 *||Apr 29, 1983||Jan 7, 1986||Possis Medical, Inc.||Method of supplying blood to blood receiving vessels|
|US4601718 *||Jul 13, 1984||Jul 22, 1986||Possis Medical, Inc.||Vascular graft and blood supply method|
|US4662884 *||Apr 25, 1984||May 5, 1987||University Of Utah Research Foundation||Prostheses and methods for promoting nerve regeneration|
|US4778467 *||Jul 10, 1986||Oct 18, 1988||The University Of Utah||Prostheses and methods for promoting nerve regeneration and for inhibiting the formation of neuromas|
|US4863457 *||Apr 22, 1988||Sep 5, 1989||Lee David A||Drug delivery device|
|US4892539 *||Feb 8, 1988||Jan 9, 1990||D-R Medical Systems, Inc.||Vascular graft|
|US4915893 *||Jul 15, 1983||Apr 10, 1990||Medtronic, Inc.||Method of preparing polyester filament material|
|US4960424 *||Jun 30, 1988||Oct 2, 1990||Grooters Ronald K||Method of replacing a defective atrio-ventricular valve with a total atrio-ventricular valve bioprosthesis|
|US5059211 *||Jun 25, 1987||Oct 22, 1991||Duke University||Absorbable vascular stent|
|US5110852 *||Oct 27, 1988||May 5, 1992||Rijksuniversiteit Te Groningen||Filament material polylactide mixtures|
|US5139505 *||Jun 22, 1990||Aug 18, 1992||Euroresearch S.R.L.||Device consisting of a heterologous collagen tube for use in hollow organ sutures|
|US5192289 *||Dec 23, 1991||Mar 9, 1993||Avatar Design And Development, Inc.||Anastomosis stent and stent selection system|
|US5254113 *||Aug 31, 1992||Oct 19, 1993||Wilk Peter J||Anastomosis method|
|US5306286 *||Feb 1, 1991||Apr 26, 1994||Duke University||Absorbable stent|
|US5332403 *||Aug 17, 1992||Jul 26, 1994||Jack Kolff||LVAD with t-shape and unidirectional valve|
|US5334216 *||Dec 10, 1992||Aug 2, 1994||Howmedica Inc.||Hemostatic plug|
|US5458570 *||Jan 12, 1994||Oct 17, 1995||May, Jr.; James W.||Absorbable catheter and method of using the same|
|US5500014 *||May 9, 1994||Mar 19, 1996||Baxter International Inc.||Biological valvular prothesis|
|US5522840 *||Nov 12, 1993||Jun 4, 1996||Krajicek; Milan||Device for the non-surgical seal of the interstice in the wall of a vessel|
|US5527337 *||Feb 22, 1994||Jun 18, 1996||Duke University||Bioabsorbable stent and method of making the same|
|US5551954 *||Oct 12, 1994||Sep 3, 1996||Scimed Life Systems, Inc.||Biodegradable drug delivery vascular stent|
|US5609626 *||Jun 22, 1994||Mar 11, 1997||Baxter International Inc.||Stent devices and support/restrictor assemblies for use in conjunction with prosthetic vascular grafts|
|US5711969 *||Apr 7, 1995||Jan 27, 1998||Purdue Research Foundation||Large area submucosal tissue graft constructs|
|US5755791 *||Apr 5, 1996||May 26, 1998||Purdue Research Foundation||Perforated submucosal tissue graft constructs|
|US5762966 *||Jan 15, 1997||Jun 9, 1998||Purdue Research Foundation||Tissue graft and method for urinary tract urothelium reconstruction and replacement|
|US5788625 *||Apr 5, 1996||Aug 4, 1998||Depuy Orthopaedics, Inc.||Method of making reconstructive SIS structure for cartilaginous elements in situ|
|US5810836 *||Nov 7, 1996||Sep 22, 1998||Myocardial Stents, Inc.||Device and method for trans myocardial revascularization (TMR)|
|US5824061 *||Jun 6, 1995||Oct 20, 1998||Baxter International Inc.||Vascular and venous valve implant prostheses|
|US5885619 *||Sep 16, 1997||Mar 23, 1999||Purdue Research Foundation||Large area submucosal tissue graft constructs and method for making the same|
|US5922022 *||Dec 31, 1997||Jul 13, 1999||Kensey Nash Corporation||Bifurcated connector system for coronary bypass grafts and methods of use|
|US5922028 *||Oct 16, 1997||Jul 13, 1999||Depuy Orthopaedics, Inc.||Multi-layered SIS tissue graft construct for replacement of cartilaginous elements in situ|
|US5944019 *||Jun 25, 1997||Aug 31, 1999||Heartstent Corporation||Closed chest coronary bypass|
|US5955110 *||Apr 5, 1996||Sep 21, 1999||Purdue Research Foundation, Inc.||Multilayered submucosal graft constructs and method for making the same|
|US5957975 *||Dec 15, 1997||Sep 28, 1999||The Cleveland Clinic Foundation||Stent having a programmed pattern of in vivo degradation|
|US5968096 *||Aug 6, 1997||Oct 19, 1999||Purdue Research Foundation||Method of repairing perforated submucosal tissue graft constructs|
|US5989287 *||May 6, 1998||Nov 23, 1999||Av Healing Llc||Vascular graft assemblies and methods for implanting same|
|US5997573 *||Jul 29, 1997||Dec 7, 1999||Baxter International, Inc.||Stent devices and support/restrictor assemblies for use in conjunction with prosthetic vascular grafts|
|US5997575 *||Sep 18, 1997||Dec 7, 1999||Purdue Research Foundation||Perforated submucosal tissue graft constructs|
|US6007576 *||Feb 6, 1998||Dec 28, 1999||Mcclellan; Scott B.||End to side anastomic implant|
|US6017352 *||Jan 16, 1998||Jan 25, 2000||Kensey Nash Corporation||Systems for intravascular procedures and methods of use|
|US6019788 *||Nov 4, 1997||Feb 1, 2000||Gore Enterprise Holdings, Inc.||Vascular shunt graft and junction for same|
|US6030395 *||May 28, 1999||Feb 29, 2000||Kensey Nash Corporation||Anastomosis connection system|
|US6036705 *||Jun 1, 1999||Mar 14, 2000||Kensey Nash Corporation||Anastomosis connection system and method of use|
|US6056762 *||May 22, 1997||May 2, 2000||Kensey Nash Corporation||Anastomosis system and method of use|
|US6063114 *||Sep 4, 1997||May 16, 2000||Kensey Nash Corporation||Connector system for vessels, ducts, lumens or hollow organs and methods of use|
|US6077296 *||Mar 4, 1998||Jun 20, 2000||Endologix, Inc.||Endoluminal vascular prosthesis|
|US6090128 *||Feb 20, 1997||Jul 18, 2000||Endologix, Inc.||Bifurcated vascular graft deployment device|
|US6093166 *||Apr 3, 1998||Jul 25, 2000||Heartstent, Llc||Coronary bypass implant|
|US6110201 *||Feb 18, 1999||Aug 29, 2000||Venpro||Bifurcated biological pulmonary valved conduit|
|US6123682 *||Apr 3, 1998||Sep 26, 2000||Heartstent Corporation||Closed chest coronary bypass|
|US6156063 *||May 28, 1998||Dec 5, 2000||Endologix, Inc.||Method of deploying bifurcated vascular graft|
|US6176880||Apr 4, 1997||Jan 23, 2001||Depuy Orthopaedics, Inc.||Tissue graft construct for replacement of cartilaginous structures|
|US6187033||Sep 4, 1997||Feb 13, 2001||Meadox Medicals, Inc.||Aortic arch prosthetic graft|
|US6187036||Dec 11, 1998||Feb 13, 2001||Endologix, Inc.||Endoluminal vascular prosthesis|
|US6187039||Dec 10, 1997||Feb 13, 2001||Purdue Research Foundation||Tubular submucosal graft constructs|
|US6197049||Feb 17, 1999||Mar 6, 2001||Endologix, Inc.||Articulating bifurcation graft|
|US6210422||Feb 16, 2000||Apr 3, 2001||Endologix, Inc.||Bifurcated vascular graft deployment device|
|US6261316||Mar 11, 1999||Jul 17, 2001||Endologix, Inc.||Single puncture bifurcation graft deployment system|
|US6273912||Feb 28, 1996||Aug 14, 2001||Impra, Inc.||Flanged graft for end-to-side anastomosis|
|US6331190||Jan 14, 2000||Dec 18, 2001||Endologix, Inc.||Endoluminal vascular prosthesis|
|US6350248||Apr 13, 2000||Feb 26, 2002||Heartstent Corporation||Expandable myocardial implant|
|US6350280||Feb 3, 2000||Feb 26, 2002||Kensey Nash Corporation||Surgical connector systems and methods of use|
|US6355050||Jun 26, 1997||Mar 12, 2002||Abbott Laboratories||Device and method for suturing tissue|
|US6358258||Sep 14, 1999||Mar 19, 2002||Abbott Laboratories||Device and method for performing end-to-side anastomosis|
|US6358284 *||Jun 2, 1999||Mar 19, 2002||Med Institute, Inc.||Tubular grafts from purified submucosa|
|US6361519||Apr 13, 2000||Mar 26, 2002||Heartstent Corporation||Mesh tip myocardial implant|
|US6371981||Nov 2, 1999||Apr 16, 2002||Av Healing Llc||Vascular graft assemblies and methods for implanting same|
|US6402767||Mar 6, 2000||Jun 11, 2002||Kensey Nash Corporation||Anastomosis connection system and method of use|
|US6454794||Jun 7, 1999||Sep 24, 2002||Heartstent Corporation||Coronary bypass implant|
|US6500202||Mar 15, 2000||Dec 31, 2002||Endologix, Inc.||Bifurcation graft deployment catheter|
|US6508835||Nov 28, 2000||Jan 21, 2003||Endologix, Inc.||Endoluminal vascular prosthesis|
|US6517553||Jan 24, 2001||Feb 11, 2003||Abbott Laboratories||Device and method for suturing of internal puncture sites|
|US6517558||Feb 1, 2001||Feb 11, 2003||Ventrica, Inc.||Methods and devices for forming vascular anastomoses|
|US6558399||Jun 30, 2000||May 6, 2003||Abbott Laboratories||Devices and method for handling a plurality of suture elements during a suturing procedure|
|US6562066 *||Mar 2, 2001||May 13, 2003||Eric C. Martin||Stent for arterialization of the coronary sinus and retrograde perfusion of the myocardium|
|US6576265||Oct 18, 2000||Jun 10, 2003||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6579538||Oct 18, 2000||Jun 17, 2003||Acell, Inc.||Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof|
|US6585762 *||Nov 1, 2000||Jul 1, 2003||Paul Stanish||Arteriovenous grafts and methods of implanting the same|
|US6589278||May 15, 1998||Jul 8, 2003||Impra, Inc.||Vascular prosthesis|
|US6629951||Jul 18, 2001||Oct 7, 2003||Broncus Technologies, Inc.||Devices for creating collateral in the lungs|
|US6635214||Sep 10, 1999||Oct 21, 2003||Ventrica, Inc.||Manufacturing conduits for use in placing a target vessel in fluid communication with a source of blood|
|US6660030||Dec 22, 2000||Dec 9, 2003||Endologix, Inc.||Bifurcation graft deployment catheter|
|US6663665||Feb 28, 2001||Dec 16, 2003||Endologix, Inc.||Single puncture bifurcation graft deployment system|
|US6666892||May 27, 1999||Dec 23, 2003||Cook Biotech Incorporated||Multi-formed collagenous biomaterial medical device|
|US6692494||Aug 7, 2000||Feb 17, 2004||Broncus Technologies, Inc.||Methods and devices for creating collateral channels in the lungs|
|US6701932||Jan 9, 2002||Mar 9, 2004||Percardia, Inc.||Method and apparatus for revascularizing a coronary vessel with an implant having a tapered myocardial leg|
|US6712812||Sep 4, 2001||Mar 30, 2004||Broncus Technologies, Inc.||Devices for creating collateral channels|
|US6730102||Nov 6, 2000||May 4, 2004||Abbott Laboratories||Systems, devices and methods for deploying needles|
|US6733522||Oct 1, 2002||May 11, 2004||Scimed Life Systems, Inc.||Aortic arch prosthetic graft|
|US6733523||Jun 26, 2001||May 11, 2004||Endologix, Inc.||Implantable vascular graft|
|US6743209||Jul 12, 2002||Jun 1, 2004||John Howell Brown||Catheter with integral anchoring means|
|US6743243||Mar 19, 1999||Jun 1, 2004||Sumit Roy||Support device for endoscopic suturless anastomosis|
|US6749606||Sep 4, 2001||Jun 15, 2004||Thomas Keast||Devices for creating collateral channels|
|US6749615||Jun 13, 2002||Jun 15, 2004||Abbott Laboratories||Apparatus and methods for performing an anastomosis|
|US6783776||Oct 25, 2002||Aug 31, 2004||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6793676||Jan 23, 2001||Sep 21, 2004||Depuy Orthopaedics, Inc.||Method of reconstructing a joint|
|US6808498||Oct 13, 1998||Oct 26, 2004||Ventrica, Inc.||Placing a guide member into a heart chamber through a coronary vessel and delivering devices for placing the coronary vessel in communication with the heart chamber|
|US6849273||Oct 25, 2002||Feb 1, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6852339||Oct 25, 2002||Feb 8, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6861074||Oct 25, 2002||Mar 1, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6869619||Oct 25, 2002||Mar 22, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6887495||Oct 25, 2002||May 3, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6890351||Sep 7, 2001||May 10, 2005||Organogenesis Inc.||Method for treating diseased or damaged organs|
|US6890562||Oct 25, 2002||May 10, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6890563||Oct 25, 2002||May 10, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6890564||Oct 25, 2002||May 10, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6893413||Jan 7, 2002||May 17, 2005||Eric C. Martin||Two-piece stent combination for percutaneous arterialization of the coronary sinus and retrograde perfusion of the myocardium|
|US6893653||Jul 8, 2003||May 17, 2005||Organogenesis Inc.||Chemical cleaning of biological material|
|US6893666||Oct 25, 2002||May 17, 2005||Acell, Inc.||Tissue regenerative composition, method of making, and method of use thereof|
|US6923820||Feb 19, 2002||Aug 2, 2005||Kensey Nash Corporation||Surgical connector systems and methods of use|
|US6926690||Sep 20, 2001||Aug 9, 2005||Percardia, Inc.||Transmyocardial shunt and its attachment mechanism, for left ventricular revascularization|
|US6951572||Aug 12, 2003||Oct 4, 2005||Endologix, Inc.||Bifurcated vascular graft and method and apparatus for deploying same|
|US6953475||Sep 30, 2003||Oct 11, 2005||Endologix, Inc.||Bifurcation graft deployment catheter|
|US6964668||May 20, 2002||Nov 15, 2005||Abbott Laboratories||Articulating suturing device and method|
|US6986735||Mar 3, 2003||Jan 17, 2006||Organogenesis Inc.||Method of making a bioremodelable vascular graft prosthesis|
|US6986751||Oct 31, 2003||Jan 17, 2006||Cabg Medical, Inc.||Grafted network incorporating a multiple channel fluid flow connector|
|US6991615||Aug 2, 2004||Jan 31, 2006||Cabg Medical, Inc.||Grafted network incorporating a multiple channel fluid flow connector|
|US7001400||Aug 29, 2000||Feb 21, 2006||Abbott Laboratories||Articulating suturing device and method|
|US7011643||Aug 5, 2003||Mar 14, 2006||Cabg Medical, Inc.||Grafted network incorporating a multiple channel fluid flow connector|
|US7022088||Feb 21, 2002||Apr 4, 2006||Broncus Technologies, Inc.||Devices for applying energy to tissue|
|US7022134||Jun 28, 2000||Apr 4, 2006||Medtronic, Inc.||Bifurcated biological pulmonary valved conduit|
|US7025773||May 7, 2001||Apr 11, 2006||Medtronic, Inc.||Methods and devices for placing a conduit in fluid communication with a target vessel|
|US7029481||Nov 6, 2000||Apr 18, 2006||Abbott Laboratories||Systems, devices and methods for suturing patient tissue|
|US7037329||Jan 7, 2002||May 2, 2006||Eric C. Martin||Bifurcated stent for percutaneous arterialization of the coronary sinus and retrograde perfusion of the myocardium|
|US7041131||Apr 11, 2003||May 9, 2006||Organogenesis, Inc.||Bioengineered vascular graft support prostheses|
|US7048747||Nov 20, 2001||May 23, 2006||Abbott Laboratories||Device and method for performing end-to-side anastomosis|
|US7060103||Feb 28, 2003||Jun 13, 2006||Organogenesis Inc.||Tissue repair fabric|
|US7087089||Jun 28, 2002||Aug 8, 2006||Cook Biotech Incorporated||Graft prosthesis devices containing renal capsule collagen|
|US7094260 *||Apr 12, 2004||Aug 22, 2006||Changhun Institute of Applied Chemistry Chinese Academy of Science||Biodegradable common bile duct stent and the method for preparing thereof|
|US7121999||Mar 3, 2003||Oct 17, 2006||Organogenesis Inc.||Method of preparing layered graft prostheses|
|US7147647 *||Apr 26, 2002||Dec 12, 2006||Medtronic, Inc.||Sintered titanium tube for the management of spinal cord injury|
|US7160326||Oct 29, 2002||Jan 9, 2007||Depuy Products, Inc.||Method and apparatus for implantation of soft tissue implant|
|US7163557 *||Jan 16, 2002||Jan 16, 2007||D Eredita Riccardo||Biodegradable auricular prosthetic device|
|US7175644||Sep 4, 2001||Feb 13, 2007||Broncus Technologies, Inc.||Devices and methods for maintaining collateral channels in tissue|
|US7189257||May 11, 2004||Mar 13, 2007||Scimed Life Systems, Inc.||Aortic arch prosthetic graft|
|US7214234||Dec 10, 2003||May 8, 2007||Medtronic, Inc.||Delivering a conduit into a heart wall to place a coronary vessel in communication with a heart chamber and removing tissue from the vessel or heart wall to facilitate such communication|
|US7214242||Mar 3, 2003||May 8, 2007||Organogenesis, Inc.||Bioengineered tubular graft prostheses|
|US7235087||Aug 29, 2003||Jun 26, 2007||Abbott Park||Articulating suturing device and method|
|US7244444||Mar 30, 2005||Jul 17, 2007||Cook Incorporated||Graft material, stent graft and method|
|US7264624||Jul 11, 2005||Sep 4, 2007||Kensey Nash Corporation||Surgical connector systems and methods of use|
|US7285235 *||Sep 29, 2003||Oct 23, 2007||Medtronic, Inc.||Manufacturing conduits for use in placing a target vessel in fluid communication with a source of blood|
|US7314489||Aug 20, 2003||Jan 1, 2008||Ethicon Endo-Surgery, Inc.||Method and apparatus to facilitate nutritional malabsorption|
|US7351247||Sep 4, 2002||Apr 1, 2008||Bioconnect Systems, Inc.||Devices and methods for interconnecting body conduits|
|US7377927||Mar 27, 2006||May 27, 2008||Abbott Laboratories||Systems, devices and methods for suturing patient tissue|
|US7390328||Dec 19, 2003||Jun 24, 2008||Abbott Laboratories||Device and method for suturing of internal puncture sites|
|US7398125 *||Apr 5, 2006||Jul 8, 2008||Peter Osypka||Suture collar with a flexible constraining means|
|US7407612 *||Feb 24, 2004||Aug 5, 2008||Saint-Gobain Ceramics & Plastics, Inc.||Method of molding a connector and tubing assembly|
|US7422563||Feb 21, 2002||Sep 9, 2008||Broncus Technologies, Inc.||Multifunctional tip catheter for applying energy to tissue and detecting the presence of blood flow|
|US7445626||Dec 16, 2003||Nov 4, 2008||Abbott Laboratories||Device and method for suturing tissue|
|US7462162||Jul 19, 2004||Dec 9, 2008||Broncus Technologies, Inc.||Antiproliferative devices for maintaining patency of surgically created channels in a body organ|
|US7462188||Sep 22, 2004||Dec 9, 2008||Abbott Laboratories||Device and method for suturing intracardiac defects|
|US7485138||Feb 6, 2002||Feb 3, 2009||Cook Biotech Incorporated||Tubular graft construct|
|US7510560||Apr 16, 2003||Mar 31, 2009||Tyco Healthcare Group Lp||Method and apparatus for anastomosis including an anchoring sleeve|
|US7520883||Apr 16, 2003||Apr 21, 2009||Tyco Healthcare Group Lp||Method and apparatus for anastomosis including an anchoring sleeve|
|US7520895||Apr 8, 2002||Apr 21, 2009||Endologix, Inc.||Self expanding bifurcated endovascular prosthesis|
|US7553316||May 10, 2004||Jun 30, 2009||Bard Peripheral Vascular, Inc.||Flanged graft for end-to-side anastomosis|
|US7578828||May 19, 2003||Aug 25, 2009||Medtronic, Inc.||Methods and devices for placing a conduit in fluid communication with a target vessel|
|US7637919 *||Jan 29, 2003||Dec 29, 2009||Olympus Corporation||Anastomosis system for performing anastomosis in body|
|US7645229||Sep 21, 2004||Jan 12, 2010||Armstrong David N||Instrument and method for endoscopic visualization and treatment of anorectal fistula|
|US7651526 *||Jan 13, 2006||Jan 26, 2010||University Of Limerick||Vascular graft|
|US7654951||Oct 4, 2004||Feb 2, 2010||Olympus Corporation||Anastomosis system for performing anastomosis in body|
|US7695483||Aug 31, 2007||Apr 13, 2010||Kensey Nash Corporation||Surgical connector systems and methods of use|
|US7708712||Jul 19, 2004||May 4, 2010||Broncus Technologies, Inc.||Methods and devices for maintaining patency of surgically created channels in a body organ|
|US7708923 *||Feb 18, 2005||May 4, 2010||Saint-Gobain Performance Plastics Corporation||Process of molding a coupling for interconnecting tubes|
|US7713552||Dec 19, 2001||May 11, 2010||Cook Biotech Incorporated||Radiopaque implantable collagenous biomaterial device|
|US7745217||Jul 11, 2006||Jun 29, 2010||Cook Biotech Incorporated||Graft prosthesis devices containing renal capsule collagen|
|US7758629 *||Mar 8, 2006||Jul 20, 2010||Thoratec Corporation||Flexible stent and method of making the same|
|US7795027||Mar 3, 2006||Sep 14, 2010||Cook Biotech Incorporated||Extracellular matrix composite materials, and manufacture and use thereof|
|US7837696||Dec 5, 2003||Nov 23, 2010||Abbott Laboratories||Articulating suturing device and method|
|US7842047||Feb 27, 2006||Nov 30, 2010||Abbott Laboratories||Articulating suturing device and method|
|US7842048||Aug 18, 2006||Nov 30, 2010||Abbott Laboratories||Articulating suture device and method|
|US7842049||Oct 25, 2006||Nov 30, 2010||Abbott Laboratories||Systems for anchoring a medical device in a body lumen|
|US7846170||Mar 20, 2007||Dec 7, 2010||Abbott Laboratories||Articulating suturing device and method|
|US7850637 *||Nov 12, 2004||Dec 14, 2010||Glaukos Corporation||Shunt device and method for treating glaucoma|
|US7850701||Aug 2, 2004||Dec 14, 2010||Abbott Laboratories||Articulating suturing device and method|
|US7857825||Nov 20, 2003||Dec 28, 2010||Cook Biotech Incorporated||Embolization device|
|US7883517||Aug 8, 2005||Feb 8, 2011||Abbott Laboratories||Vascular suturing device|
|US7887576||May 19, 2009||Feb 15, 2011||Cook Incorporated||Endoluminal device with extracellular matrix material and methods|
|US7892246||Sep 4, 2002||Feb 22, 2011||Bioconnect Systems, Inc.||Devices and methods for interconnecting conduits and closing openings in tissue|
|US7892247||Oct 3, 2002||Feb 22, 2011||Bioconnect Systems, Inc.||Devices and methods for interconnecting vessels|
|US7892277||May 3, 2006||Feb 22, 2011||Endologix, Inc.||Self expanding bifurcated endovascular prosthesis|
|US7897167||Jun 21, 2006||Mar 1, 2011||Cook Incorporated||Implantable graft to close a fistula|
|US7909886||Mar 24, 2006||Mar 22, 2011||Organogenesis, Inc.||Tissue repair fabric|
|US7993356||Sep 29, 2006||Aug 9, 2011||Medtronic, Inc.||Delivering a conduit into a heart wall to place a coronary vessel in communication with a heart chamber and removing tissue from the vessel or heart wall to facilitate such communication|
|US7993357||Apr 15, 2008||Aug 9, 2011||Tyco Healthcare Group||Method and apparatus for anastomosis including an anchoring sleeve|
|US7998154||Apr 16, 2003||Aug 16, 2011||Tyco Healthcare Group Lp||Method and apparatus for radical prostatectomy anastomosis|
|US7998155||Apr 16, 2003||Aug 16, 2011||Tyco Healthcare Group Lp||Method and apparatus for anastomosis including annular joining member|
|US8034100||Nov 25, 2003||Oct 11, 2011||Endologix, Inc.||Graft deployment system|
|US8038688||Nov 14, 2005||Oct 18, 2011||Abbott Laboratories||Articulating suturing device and method|
|US8048092||Dec 6, 2010||Nov 1, 2011||Abbott Laboratories||Articulating suturing device and method|
|US8048108||Feb 4, 2009||Nov 1, 2011||Abbott Vascular Inc.||Vascular closure methods and apparatuses|
|US8049059||Oct 25, 2002||Nov 1, 2011||Cook Biotech Incorporated||Medical graft device with meshed structure|
|US8057491||Dec 13, 2010||Nov 15, 2011||Abbott Laboratories||Articulating suturing device and method|
|US8083754||Aug 8, 2005||Dec 27, 2011||Abbott Laboratories||Vascular suturing device with needle capture|
|US8083804||Apr 16, 2003||Dec 27, 2011||Tyco Healthcare Group Lp||Method and apparatus for anastomosis including annular joining member|
|US8092490||Aug 16, 2005||Jan 10, 2012||The General Hospital Corporation||Photochemical tissue bonding|
|US8109950||Mar 16, 2009||Feb 7, 2012||Tyco Healthcare Group Lp||Method and apparatus for anastomosis including an anchoring sleeve|
|US8118856||Jul 27, 2010||Feb 21, 2012||Endologix, Inc.||Stent graft|
|US8137364||Sep 11, 2003||Mar 20, 2012||Abbott Laboratories||Articulating suturing device and method|
|US8147535||Jul 25, 2005||Apr 3, 2012||Endologix, Inc.||Bifurcation graft deployment catheter|
|US8152752 *||Nov 12, 2004||Apr 10, 2012||Glaukos Corporation||Shunt device and method for treating glaucoma|
|US8167925||Mar 25, 2010||May 1, 2012||Endologix, Inc.||Single puncture bifurcation graft deployment system|
|US8172860||Dec 12, 2008||May 8, 2012||Abbott Laboratories||Articulating suturing device and method|
|US8177799||Dec 2, 2009||May 15, 2012||Tyco Healthcare Lp||Method and apparatus for anastomosis|
|US8187619||Apr 16, 2010||May 29, 2012||Cook Biotech Incorporated||Enhanced compositions containing cells and extracellular matrix materials|
|US8192763||Jul 23, 2008||Jun 5, 2012||Cook Biotech Incorporated||Processed ECM materials with enhanced component profiles|
|US8202281||Nov 29, 2010||Jun 19, 2012||Abbott Laboratories||Systems for anchoring a medical device in a body lumen|
|US8211122||Aug 9, 2007||Jul 3, 2012||Abbott Laboratories||Device for suturing intracardiac defects|
|US8215314 *||Dec 9, 2003||Jul 10, 2012||The General Hospital Corporation||Photochemical tissue bonding|
|US8216295||Jul 1, 2009||Jul 10, 2012||Endologix, Inc.||Catheter system and methods of using same|
|US8236040||Apr 11, 2008||Aug 7, 2012||Endologix, Inc.||Bifurcated graft deployment systems and methods|
|US8252008||Nov 29, 2010||Aug 28, 2012||Abbott Laboratories||Articulating suturing device and method|
|US8257368||Aug 9, 2007||Sep 4, 2012||Abbott Laboratories||Device for suturing intracardiac defects|
|US8267947||Jul 21, 2006||Sep 18, 2012||Abbott Laboratories||Vascular suturing device|
|US8313498||Feb 7, 2011||Nov 20, 2012||Abbott Laboratories||Vascular suturing device|
|US8323298||Nov 19, 2010||Dec 4, 2012||Abbott Laboratories||Articulating suturing device and method|
|US8328837||Dec 7, 2005||Dec 11, 2012||Xlumena, Inc.||Method and apparatus for performing needle guided interventions|
|US8333742||May 7, 2009||Dec 18, 2012||Glaukos Corporation||Method of delivering an implant for treating an ocular disorder|
|US8349019||Dec 6, 2011||Jan 8, 2013||Covidien Lp||Method and apparatus for anastomosis including annular joining member|
|US8357192||Mar 11, 2011||Jan 22, 2013||Endologix, Inc.||Bifurcated graft deployment systems and methods|
|US8357193||May 3, 2010||Jan 22, 2013||Xlumena, Inc.||Apparatus and method for deploying stent across adjacent tissue layers|
|US8361088||Oct 23, 2008||Jan 29, 2013||Abbott Laboratories||Device and method for suturing intracardiac defects|
|US8366651||Aug 4, 2008||Feb 5, 2013||Bioconnect Systems, Inc.||Implantable flow connector|
|US8377080||Apr 13, 2010||Feb 19, 2013||Kensey Nash Corporation||Surgical connector systems and methods of use|
|US8388568 *||May 7, 2009||Mar 5, 2013||Glaukos Corporation||Shunt device and method for treating ocular disorders|
|US8388643||Aug 5, 2005||Mar 5, 2013||The Regents Of The University Of California||Bioabsorbable polymeric implants and a method of using the same to create occlusions|
|US8409167||Oct 5, 2006||Apr 2, 2013||Broncus Medical Inc||Devices for delivering substances through an extra-anatomic opening created in an airway|
|US8409625||Jan 9, 2009||Apr 2, 2013||Acell, Inc.||Conditioned decellularized native tissues for tissue restoration|
|US8419753||Oct 7, 2008||Apr 16, 2013||Abbott Laboratories||Suturing device with split arm and method of suturing tissue|
|US8425539||Oct 4, 2007||Apr 23, 2013||Xlumena, Inc.||Luminal structure anchoring devices and methods|
|US8430893||Aug 23, 2012||Apr 30, 2013||Abbott Laboratories||Articulating suturing device and method|
|US8439942||Dec 3, 2010||May 14, 2013||Cook Bioteck Incorporated||Embolization device|
|US8449607||Jul 26, 2012||May 28, 2013||Cormatrix Cardiovascular, Inc.||Prosthetic tissue valve|
|US8454632 *||Apr 21, 2009||Jun 4, 2013||Xlumena, Inc.||Tissue anchor for securing tissue layers|
|US8455008||Jun 5, 2012||Jun 4, 2013||Cook Biotech Incorporated||Processed ECM materials with enhanced component profiles|
|US8486095||Jul 27, 2011||Jul 16, 2013||Covidien Lp||Method and apparatus for radical prostatectomy anastomosis|
|US8491646||Jul 15, 2010||Jul 23, 2013||Endologix, Inc.||Stent graft|
|US8501217||Feb 1, 2011||Aug 6, 2013||Cook Medical Technologies Llc||Implantable graft to close a fistula|
|US8512360||Feb 13, 2004||Aug 20, 2013||Medtronic, Inc.||Conduits for use in placing a target vessel in fluid communication with source of blood|
|US8523931||Jan 12, 2007||Sep 3, 2013||Endologix, Inc.||Dual concentric guidewire and methods of bifurcated graft deployment|
|US8535349||Jul 1, 2008||Sep 17, 2013||Cook Biotech Incorporated||Fistula grafts having a deflectable graft body portion|
|US8541372||Jan 3, 2011||Sep 24, 2013||Cook Biotech Incorporated||Isolated extracellular matrix material including subserous fascia|
|US8574244||Dec 19, 2007||Nov 5, 2013||Abbott Laboratories||System for closing a puncture in a vessel wall|
|US8591535||Jul 21, 2011||Nov 26, 2013||Covidien Lp||Method and apparatus for anastomosis including an anchoring sleeve|
|US8591930||Apr 28, 2008||Nov 26, 2013||Cook Biotech Incorporated||Growth factor modified extracellular matrix material preparation and methods for preparation and use thereof|
|US8597309||Sep 13, 2012||Dec 3, 2013||Abbott Laboratories||Suturing device with split arm and method of suturing tissue|
|US8608724||Nov 4, 2010||Dec 17, 2013||Broncus Medical Inc.||Devices for delivering substances through an extra-anatomic opening created in an airway|
|US8617196||Dec 10, 2012||Dec 31, 2013||Xlumena, Inc.||Method and apparatus for performing needle guided interventions|
|US8642735||Apr 18, 2012||Feb 4, 2014||Children's Medical Center Corporation||Biologic replacement for fibrin clot|
|US8652191||Nov 20, 2008||Feb 18, 2014||Cook Biotech Incorporated||Tubular graft construct|
|US8663086||Sep 28, 2010||Mar 4, 2014||Cook Biotech Incorporated||Medical reinforcement graft|
|US8663248||Dec 12, 2008||Mar 4, 2014||Abbott Laboratories||Articulating suturing device and method|
|US8663252||Sep 1, 2010||Mar 4, 2014||Abbott Cardiovascular Systems, Inc.||Suturing devices and methods|
|US8679176||Sep 14, 2012||Mar 25, 2014||Cormatrix Cardiovascular, Inc||Prosthetic tissue valve|
|US8690816||Aug 4, 2008||Apr 8, 2014||Bioconnect Systems, Inc.||Implantable flow connector|
|US8696744||May 24, 2012||Apr 15, 2014||Cormatrix Cardiovascular, Inc.||Extracellular matrix material valve conduit and methods of making thereof|
|US8709034||May 13, 2011||Apr 29, 2014||Broncus Medical Inc.||Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall|
|US8709069||Apr 21, 2006||Apr 29, 2014||C. R. Bard, Inc.||Flanged graft with trim lines|
|US8728144||Dec 26, 2006||May 20, 2014||Cook Medical Technologies Llc||Endoluminal device including a mechanism for proximal or distal fixation, and sealing and methods of use thereof|
|US8764791||May 30, 2007||Jul 1, 2014||Cook Medical Technologies Llc||Implantable graft to close a fistula|
|US8764812||Jan 18, 2013||Jul 1, 2014||Endologix, Inc.||Bifurcated graft deployment systems and methods|
|US8771217||Dec 13, 2010||Jul 8, 2014||Glaukos Corporation||Shunt device and method for treating ocular disorders|
|US8777967||Dec 14, 2006||Jul 15, 2014||Xlumena, Inc.||Methods and devices for anchoring to tissue|
|US8784400||May 16, 2012||Jul 22, 2014||Broncus Medical Inc.||Devices for delivering substances through an extra-anatomic opening created in an airway|
|US8784437||Jun 8, 2006||Jul 22, 2014||Xlumena, Inc.||Methods and devices for endosonography-guided fundoplexy|
|US8784889||Jan 30, 2007||Jul 22, 2014||Cook Biotech Incorporated||Graft with increased resistance to enzymatic degradation|
|US8795384||Jan 10, 2008||Aug 5, 2014||Cook Biotech Incorporated||Implantable devices useful for reinforcing a surgically created stoma|
|US8808350||Feb 29, 2012||Aug 19, 2014||Endologix, Inc.||Catheter system and methods of using same|
|US8821564||Feb 16, 2012||Sep 2, 2014||Endologix, Inc.||Stent graft|
|US8840917||Jul 15, 2013||Sep 23, 2014||Cook Medical Technologies Llc||Implantable graft to close a fistula|
|US8845719||May 24, 2012||Sep 30, 2014||Cormatrix Cardiovascular, Inc||Extracellular matrix material conduits and methods of making and using same|
|US8858573||Apr 24, 2012||Oct 14, 2014||Abbott Cardiovascular Systems, Inc.||Apparatus and method for suturing body lumens|
|US8864778||Apr 10, 2012||Oct 21, 2014||Abbott Cardiovascular Systems, Inc.||Apparatus and method for suturing body lumens|
|US8915941||Jun 14, 2012||Dec 23, 2014||Cook Medical Technologies Llc||Fistula closure devices and methods|
|US8920442||Aug 23, 2006||Dec 30, 2014||Abbott Vascular Inc.||Vascular opening edge eversion methods and apparatuses|
|US8920516||Jan 26, 2010||Dec 30, 2014||Cook Biotech Incorporated||Graft prosthesis, material and methods|
|US8932316||Apr 7, 2014||Jan 13, 2015||Broncus Medical Inc.||Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall|
|US8945202||Apr 28, 2010||Feb 3, 2015||Endologix, Inc.||Fenestrated prosthesis|
|US8956378||Feb 27, 2009||Feb 17, 2015||Cook Biotech Incorporated||Coated embolization device|
|US8961446||Dec 16, 2012||Feb 24, 2015||Bioconnect Systems Inc.||Implantable flow connector|
|US8998932||Jun 18, 2012||Apr 7, 2015||Abbott Laboratories||Systems for anchoring a medical device in a body lumen|
|US20040073157 *||Oct 9, 2003||Apr 15, 2004||Heartstent Corporation||Method and apparatus for performing coronary artery bypass surgery|
|US20090254104 *||Mar 27, 2009||Oct 8, 2009||Children's Medical Center Corporation||Methods and collagen products for tissue repair|
|US20090281557 *||Apr 21, 2009||Nov 12, 2009||Xlumena, Inc.||Tissue anchor for securing tissue layers|
|US20100100170 *||Oct 16, 2009||Apr 22, 2010||Boston Scientific Scimed, Inc.||Shape memory tubular stent with grooves|
|US20110040230 *||Mar 16, 2010||Feb 17, 2011||Laufer Michael D||Minimally invasive gastrointestinal bypass|
|CN100579589C||Aug 20, 2004||Jan 13, 2010||伊西康内外科公司||Method and apparatus to facilitate nutritional absorption for nutrient malabsorption people|
|DE3390385C2 *||Dec 8, 1983||Jul 7, 1994||Possis Medical Inc||Gefäßimplantate|
|DE19735141A1 *||Aug 13, 1997||Apr 30, 1998||Heartstent Corp||Vorrichtung und Verfahren zum Durchführen einer Operation eines Koronararterienbypasses|
|EP0144398A1 *||May 21, 1984||Jun 19, 1985||Baxter Travenol Laboratories, Inc.||Barrier layer for implantable tendons and ligaments|
|EP0172279A1 *||Aug 13, 1984||Feb 26, 1986||John Augustin Jurgutis||Human ligament replacement|
|EP1057457A1 *||May 30, 2000||Dec 6, 2000||Bourhane-Eddine Benelouezzane||Biliary shunt prosthesis|
|EP1508312A1 *||Aug 20, 2004||Feb 23, 2005||Ethicon Endo-Surgery, Inc.||Apparatus to facilitate nutritional malabsorption|
|EP1955721A1||Aug 22, 1997||Aug 13, 2008||Cook Biotech, Inc.||Collagen-based graft prosthesis|
|EP1985320A1||May 27, 1999||Oct 29, 2008||Cook Biotech, Inc.||A multi-formed collagenous biomaterial medical device|
|EP2532310A2||Apr 29, 2006||Dec 12, 2012||Cook Biotech Incorporated||Volumetric grafts for treatment of fistulae and related methods and systems|
|WO1982004390A1 *||Jun 8, 1982||Dec 23, 1982||Kenneth Z Kurland||Means and method of implanting bioprosthetics|
|WO1984002266A1 *||Dec 8, 1983||Jun 21, 1984||Possis Medical Inc||Vascular graft and blood supply method|
|WO1993020757A2 *||Apr 14, 1993||Oct 28, 1993||Baxter Int||Vascular implant system|
|WO1999033403A1||Nov 19, 1998||Jul 8, 1999||Kensey Nash Corp||Bifurcated connector system for coronary bypass grafts|
|WO2002013675A2 *||Aug 6, 2001||Feb 21, 2002||Dialysis Access Solutions Inc||Distally narrowed vascular grafts|
|WO2003028546A2 *||Oct 2, 2002||Apr 10, 2003||Univ Loma Linda Med||Method and device for creating microvascular anastomoses|
|WO2006013234A1 *||Jul 2, 2004||Feb 9, 2006||Daniel Roux||Vascular prosthesis for adapting diameter differences between two ends of a replaceable blood vessel segment|
|WO2012080390A1||Dec 15, 2011||Jun 21, 2012||Meteso Ag||Medical device|