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Publication numberUS2167251 A
Publication typeGrant
Publication dateJul 25, 1939
Filing dateAug 20, 1938
Priority dateAug 20, 1938
Publication numberUS 2167251 A, US 2167251A, US-A-2167251, US2167251 A, US2167251A
InventorsAllen Rogers
Original AssigneeDavis & Geck Inc
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Surgical tape of submucosa tissue
US 2167251 A
Abstract  available in
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Claims  available in
Description  (OCR text may contain errors)

Patented July .25, 1939 .suacrcu. TAPE or smsnwcosa 'rrssun Allen Rogers, Brooklyn, N. Y., assignor to Davis & Geck, Inc., Brooklyn, N. Y., a corporation of New York No Drawing.

No. 726,328, May 18, 1934.

Continuation of application Serial This application August 20, 1938, Serial No. 225,943

40laims.

. properties adversely aifected by heat sterilization,

and to devise a novel method of preparing the same.

In the application of so-called catgut tothe healing of wounds, the material principally used is composed of a layer of intestinal tissue. In the preparation of such raw catgut strings, the

small intestine, which is tubular, is cut longitudi-' nally at two or three different points so that the intestine is actually divided longitudinally into halves or thirds, making two or three strips. These strips are subsequently cleaned, plumped, and twisted together in the form of a string, which is then thoroughly washed and dried under tension. This string may be of any size desired and has the property, when embedded. in living tissue, of becoming eventually absorbed. Such material is used in surgical operations and is technically known as a surgical suture or ligature, depending upon the manner of use. Its application is very diversified, finding its most common use in operations performed in tissues in which the stitches cannot be removed after the wound has healed. Being of animal origin, this material becomes eventually a part of the scar tissue which is formed, and results in added strength being given to the surfaces thus held in apposition.

In operating on certain internal organs, the tissues of which are extremely soft, the kidney being an excellent example, the surgeon experiences difiiculty in bringing about satisfactory apposition of the incised edges of the wound in the organ, as the ordinary suture has a tendency to cut through or pull out of the tissue. It was this difiiculty that suggested an investigation of some means of producing a surgical suture or ligature which could be applied to an internal organ as one might tie up a bundle with tape. In other words, the problem was to produce a fiat surgical ligature or suture in the form of a ribbon, which would have all the characteristics of so-called catgut as regards strength and absorbability, and the physical properties of which would not be adversely affected by heat-sterilization, and. at the same time would be fiat like a ribbon rather than round like a string. Such a ribbon has many advantages and a wide field of usefulness in those surgical situations where it is desirable to distribute the pressure, incidental to tissue approximation, over a broad surface, and where support is needed.

Cattle intestine, such as that of the sheep or the ox, consists of four distinct layers of tissue. On the outside is the serous membrane, next a muscular layer of circular and longitudinal flbres; next a submucous layer, and finally the mucous membrane. In preparing a ribbon gut according to this invention, the animal intestine is subjected to the same character of stripping, scraping, sliming and cleaning as is used in making the ordinary surgical catgut string, three of the above layers of intestinal tissue being removed, leaving only the submucous layer.

The resulting submucous layer in the form of 'a comparatively wide sheet is then cut into short strips and spread on smooth surfaces ofa material to which the submucous layer or membrane will properly adhere while drying, but from which it can be readily removed or stripped when thoroughly dry. These surfaces may be metal plates, preferably tinned, or they may be wax-coated glass or porcelain surfaces, either fiat, curved, or cylindrical in shape. For very long ribbons, a tubular drying surface may be used and the membrane wound helically around the same. After being applied to the drying surface, moderate pressure is applied to the sheet of submucous layer or membrane and the same permitted to dry at approximately 20 C. When dry, the sheet is removed from the drying surface and cut into the desired width.

In the manufacture of ordinary twisted catgut strings, the strips of intestinal tissue are cut into the desired widths prior to being twisted. This is undesirable for the present purpose in that the drying operation has a tendency to produce rough or uneven edges. This fact is of no moment in twisted strings because in the twisting operation the rough edges merge with each other and any remaining roughness is removed by polishing in subsequent operations. In the present instance, however, it is desirable to dry the sheets first and then cut the same into ribbons of a desired width. This has the efiect of securing perfectly straight smooth edges which are not subsequently disturbed.

If as in some cases, a heavy ribbon is desired, a number of the cleaned, wet intestinal tissue strips are superimposed one on the other in such a manner that the resulting material is laminated to form a plurality of layers or plys. In this case, only the first strip isin contact with the made to adhere to each other and to the first strip after being placed together, by means-of a rubber roller repeatedly applied with moderate pressure, in such manner that the roller always moves in one direction. The rolling under pres sure is continued until all air bubbles are forced out from between the various layers which are thus made to adhere together to form a homogeneous laminated membrane. This laminating and drying process may be carried out at room temperature of approximately 20 C.

For those surgical conditions which require that the ribbon should resist absorption in the tissues for various periods of time. I have employed successfully ribbon gut made in accordance with the above methods; but which has also been subjected to various degrees of tanning by the usual or well-known chrome-tanning process as applied to animal fibers for the purpose of delaying absorption. By varying the strength of the chemicals used, as well as the duration of the chrome-tanning process, the degree of tanning may be regulated.

One outstanding advantage of ribbon gut from aroma v drying surface, the other intestinal strips being a surgical standpoint is that its physical propeties are unimpaired by intense heat. 'Ihis material, therefore, readilylends itself to the heat method of sterilization, which does not aflect its tensile strength nor its absorptive properties.

While the invention has been described with particular .reference to special materials and methods of treatment, yet obviously I do not wish to be limited thereto but the invention is to be construed broadly and restricted only by the scope of the claims.

I claim:

1. As a complete article of manufacture, a surgical tape comprising a ribbon of submucous animal intestinal tissue.

2. As a complete article of manufacture. a surgical tape consisting of a ribbon of submucous animal intestinal tissue.

3. As a complete article of manufacture, a surgical tape comprising a laminated ribbon of submucous animal intestinal tissue.

4. As a complete article of manufacture, a surgical tape comprising a tanned ribbon of submucous animal intestinal tissue.

ALLEN ROGERS.

Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US2487041 *Mar 7, 1944Nov 8, 1949Bower John OWound binding element and method of manufacture
US2570443 *Nov 24, 1945Oct 9, 1951American Viscose CorpMethod of producing products of animal fibers
US2598608 *Jun 11, 1946May 27, 1952Research CorpPreparation of collagenous materials
US2686708 *Aug 26, 1949Aug 17, 1954Armour & CoAcid treatment of sutures
US5922028 *Oct 16, 1997Jul 13, 1999Depuy Orthopaedics, Inc.Multi-layered SIS tissue graft construct for replacement of cartilaginous elements in situ
US8187619Apr 16, 2010May 29, 2012Cook Biotech IncorporatedEnhanced compositions containing cells and extracellular matrix materials
US8192763Jul 23, 2008Jun 5, 2012Cook Biotech IncorporatedProcessed ECM materials with enhanced component profiles
US8455008Jun 5, 2012Jun 4, 2013Cook Biotech IncorporatedProcessed ECM materials with enhanced component profiles
US8541372Jan 3, 2011Sep 24, 2013Cook Biotech IncorporatedIsolated extracellular matrix material including subserous fascia
US8591930Apr 28, 2008Nov 26, 2013Cook Biotech IncorporatedGrowth factor modified extracellular matrix material preparation and methods for preparation and use thereof
US8663086Sep 28, 2010Mar 4, 2014Cook Biotech IncorporatedMedical reinforcement graft
US8795384Jan 10, 2008Aug 5, 2014Cook Biotech IncorporatedImplantable devices useful for reinforcing a surgically created stoma
US8956378Feb 27, 2009Feb 17, 2015Cook Biotech IncorporatedCoated embolization device
US9044455Jul 26, 2013Jun 2, 2015Cook Biotech IncorporatedIsolated extracellular matrix material including subserous fascia
US20080167729 *Jan 10, 2008Jul 10, 2008Nelson Christopher MImplantable devices useful for reinforcing a surgically created stoma
US20080286268 *Jul 23, 2008Nov 20, 2008Johnson Chad EProcessed ecm materials with enhanced component profiles
US20080299171 *Apr 28, 2008Dec 4, 2008Hiles Michael CGrowth factor modified extracellular matrix material and methods for preparation and use thereof
US20090142400 *May 30, 2008Jun 4, 2009Hiles Michael CAnalgesic coated medical product
US20090270978 *Oct 29, 2009Virkler Joel ACoated embolization device
US20100203023 *Apr 16, 2010Aug 12, 2010Johnson Chad EEnhanced compositions containing cells and extracellular matrix materials
US20110077455 *Sep 28, 2010Mar 31, 2011Mark DuncanMedical reinforcement graft
US20110152196 *Jun 23, 2011Bhavin ShahIsolated extracellular matrix material including subserous fascia
WO1995006439A1 *Aug 31, 1994Mar 9, 1995Depuy IncCatgut orthopaedic appliance
Classifications
U.S. Classification606/229
International ClassificationA61L17/00, A61L17/08
Cooperative ClassificationA61L17/08
European ClassificationA61L17/08