Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.


  1. Advanced Patent Search
Publication numberUS2196323 A
Publication typeGrant
Publication dateApr 9, 1940
Filing dateNov 8, 1937
Priority dateNov 8, 1937
Publication numberUS 2196323 A, US 2196323A, US-A-2196323, US2196323 A, US2196323A
InventorsEnz Walter W F, Norton John F
Original AssigneeUpjohn Co
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Sterile solution dispensing bottle
US 2196323 A
Previous page
Next page
Description  (OCR text may contain errors)

p 1940- J. F. NORTON a-r-m. 2,196,323


John K War-f0 Wfl//6/ 14 f 177 QM -4 1 I H TTORNEYS Patented Apr. 9, 1940 UNITED STATES STERILE SOLUTION msrnnsmc some John F. Norton and Walter W. F. Enz, Kala mazoo, Mich., assignors to The Upjohn Company, Kalamazoo, Mich.

Application November 8, 1937,'Serial No. 173,452

- 1 Claim.

This invention relates to packages or containers for dispensing sterile solutions or the like. Heretofore sterile solutions or the like have been put up in bottles or other containers and have been sterilized. The sterilized container and its contents are then sent to hospitals or the like for use. In withdrawing the sterile solution from the bottle or container 2. tube carries the liquid from the bottle which is inverted to permit the withdrawal and another tube is ordinarily employed to permit air to'pass into the bottle or container to facilitate the flow of the liquid. In carrying out this method of dispensing the sterile solution, bacteria or dirt particles from the air may be carried into the sterile solution. Heretofore attempts have been made to prevent the carrying of bacteria or dirt particles to the sterile solution. Various complicated stoppers or filtering devices have been provided. In certain of these a tube through which air is admitted is applied to an air inlet in the bottle and some cotton is placed in the tube to filter out the bacteria or dirt particles. In using such a device considerable care must be taken to hold the tube with the cotton filter above the level of the liquid in the bottle at all times because if the cotton becomes moistened it is a notoriously inefiicient bacteriological filter. In using the cotton filter, there is a possibility that a small fiber of the cotton will be pulled into the sterile solution. This is extremely dangerous because the cotton may be thus introduced into the patient receiving the sterile solutiifin. If this happens, an embolism is apt to res Certain complicated capsor stoppers have been devised for filtering the air as it is admitted to the bottle or container. These caps are not very satisfactory because they must be removed and sterilized after each use. In using them it is also necessary to uncap the container with the sterile solution and apply the sterilized cap or stopper. This exposes the sterile solution to the,

air for a short time and may result in contamination of the sterile solution.

The objects of this invention are:

First, to produce a new and improved dispensing package or container for sterile solutions or the like.

Second, to provide such a package or container which eliminates the disadvantages above set forth. a

Third, to provide such a package or container in which the sterile solution is kept sterile until it is actually introduced into the patient.

Fourth, to provide such a package or container in which the air admitted to the container. is thoroughly washed to remove contaminants.

Fifth, to provide such a package or container which can be made up easily and inexpensively and which may be destroyed after use.

Sixth, to provide such a package or container in which the chances for contamination of the sterile solution are reduced to a minimum.

Further objects and advantages pertaining todetails and economies of construction and oper- Fig. 2 is a view of the right side of the upper portion of Fig. 1.

Fig. 3 is a detail view partly in section of the anti-siphonic trap employed in our invention.

Fig. 4 is a partial elevational view partly in section of the top of the package or bottle showing the method of capping employed.

Referring to the drawing, I is a suitable bottle or container preferably made of glass. Lugs 2 are formed near the bottom to engage a holder 3 which consists of a pair of arms 4 pivoted together with the rivet 5. Each arm 4 carries at its end a fork 6 adapted to embrace the end of the bottle and engage the lug 2 when the bottle is held in inverted position for the dispensing of the liquid contained in the bottle. One fork 6 has at its ends apertures 'l and the other fork has at its ends lugs 8 adapted to fit within the apertures 1 when the holder is in position. The ends of the forks having the apertures I extend outside of the forks containing the lugs 8 and snap into place as shown in Figs. 1 and 2.

The bottle is provided with a stopper 9 of rubber or other suitable material which is fittedin the mouth ll) of the bottle. A liquid outlet ll having a short section of tube l2 which may be of glass or any other suitable substance is provided. A rubber tube l3 may be fitted over the tube I2 to carry the sterile solution to its point of discharge. An air inlet I4 is provided in the stopper 9 and a tube I5 of glass extends from the air inlet l4 inside the bottle. The free end I6 01' this tube extends to a point adjacent the bottom of the bottle and it will be apparent that when the bottle is in the upright position the free end [6 of the tube 15 will be immersed in the liquid contained in the bottle it the bottle has its full content or if liquid is present in any appreciable amount.

In Fig. 1 the bottle is shown in inverted position for dispensing the liquid. The liquid shown at I! rests against the, stopper 9 of the bottle and the free end I 6 of the tube extends above the liquid level which is indicated at it. .At a point spaced from the free end [6 of the tube l5, we provide an anti-siphonic trap l9. This trap consists of a loop 20 formed in the tube and an enlargement 2! formed in the tube adjacent the loop 20 and between the free end l6 of the tube and the loop 20. We prefer to use this arrangement of anti-siphonic trap because the tube I is preferably of glass and the enlargement 2! is formed by heating and blowing the v glass, whereas the bends forming the loop 2|! are formed by heating the glass. It is possible to form the trap more satisfactorily with this ar rangement and it is also possible to make the enlargement 2| large enough to satisfactorily break up the air bubbles formed during use of the device and at the same time permit the easy insertion of the tube and its trap into the bottle or container during filling.

By locating the trap at a point spaced from the free end 16 of the tube, we eliminate breakage during handling and shipping because the weight of the loop 20 and the enlargement 2| is moved closer to the stopper or point of support of the tube IS.

The bottle is ordinarily kept in an upright position but when it is desired to withdraw the liquid from the bottle it is inverted ,to the position shown in Fig. 1. When the bottle is inverted, a portion of the liquid I! which is contained in the bottle is trapped in the trap l9. When the liquid is withdrawn from the bottle, air passes in through the tube 15 and through the trap to the inside of the bottle. trap I9 is shown in Fig. 3 at 22 and as the air passes through the tube I5 it reaches the trapped liquid 22 and carries the liquid up to the enlargement 2| of the tube. breaks on reaching the enlargement 2| and the liquid flows back to the bottom of the loop to the position indicated by the numeral 22 and as more air passes through the tube l5, this operation is repeated. The air entering the bottle is thus thoroughly washed, eliminating contaminants which might be otherwise carried to the sterile solution in the bottle. There is no danger The liquid which is trapped in the The bubble thus formed.

01' cotton fibers passing into the solution and the washing of the air is assured by trapping oi. the liquid.

The tube I5 and the trap II are both sterilized when the sterile solution is sterilized and need no further sterilization. They are inexpensive and can be inserted in the bottle and can be thrown away when the solution has been used.

When the bottle is stored, the holder 3 is not in position on the bottle. The cork is held in position by a screw cap 23 and the ends of the tubes I2 and ii are closed by rubber caps 24 and an outer screw cap 25 fits over the entire mouth of the bottle as shown in Fig. 4. In order to use the bottle it is necessary only to remove the outer cap 25 and the rubber caps 24. The tubes i2 and I5 are both in sterile condition and all that is necessary is to apply a sterile tube It to the tube I! as shown in Fig. 1. Such sterile tube must of necessity be supplied so that no additional sterilization operations are required and it is not necessary to open the sterile solution bottle before use.

Having thus described our invention, what we claim as new and desire to secure by Letters Paten is:

In a dispensing package for sterile solutions or the like, the combination of a bottle, a stopper for said bottle having an outlet for liquid and an inlet for air, a tube extending inside the bottle and from the air inlet of the stopper with its free end adjacent the bottom of the bottle, whereby said'free end will be immersed in liquid contained in the bottle when the bottle has its full liquid content and is upright but will extend above the liquid level in the bottle when the bottle has its full liquid content and is inverted for the withdrawal of liquid, and a trap formed in the tube at a point spaced from the free end of the tube in order to reduce the strain on the tube during handling of the package, said trap being located between said free end of the tube and said stopper and within the bottle,.said trap comprising a loop formed in the tube, and an enlargement in the tube adjacent the loop and between the loop and the free end of the tube, whereby liquid from the bottle is trapped and retained in the loop when the bottle is inverted for the withdrawal 'of liquid whereby air passing into the bottle as the liquid is withdrawn will pass through the trapped liquid. JOHN F. NORTON.


Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US2500199 *Apr 3, 1946Mar 14, 1950Baxter Laboratories IncDispensing of liquids
US2539559 *May 31, 1947Jan 30, 1951Sherwin Williams CoSpraying device
US2705955 *Dec 18, 1952Apr 12, 1955Baxter Laboratories IncParenteral administration set and air inlet closure structure for use therein
US4440315 *Nov 20, 1981Apr 3, 1984Lev SlobodnikAuto flow system
US4681245 *Mar 25, 1985Jul 21, 1987Harvey Robert DMethod and apparatus for dispensing oil well proppant additive
US4840292 *Mar 24, 1988Jun 20, 1989Harvey Robert DMethod and apparatus for dispensing oil well proppant additive
US4871359 *Jan 30, 1987Oct 3, 1989Presidentia Medical AbAdapter for drop unit
US6296223 *Jun 8, 1999Oct 2, 2001Pharmagraphics (Southeast) L.L.C.Hanger label
US6361010 *Aug 2, 2000Mar 26, 2002Pharmagraphics (Southeast), L.L.C.Hanger label
US6644613Sep 26, 2001Nov 11, 2003Pharmagraphics (Southeast), L.L.C.Hanger label
US7080686Nov 12, 2003Jul 25, 2006David BeckhardtDevices and methods for extraction, transportation and/or release of material
U.S. Classification604/405, 220/758, 222/188, 215/399
International ClassificationA61M5/14, A61J1/00, A61J1/05
Cooperative ClassificationA61M5/1417, A61J1/05
European ClassificationA61M5/14R4, A61J1/05