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Publication numberUS2223611 A
Publication typeGrant
Publication dateDec 3, 1940
Filing dateMay 22, 1939
Priority dateMay 22, 1939
Publication numberUS 2223611 A, US 2223611A, US-A-2223611, US2223611 A, US2223611A
InventorsGross Richard E
Original AssigneeGross Richard E
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
US 2223611 A
Abstract  available in
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Claims  available in
Description  (OCR text may contain errors)

R. E. GROSS Dec. 3, 1940.,

SYRINGE Filed May 22, 1939 Patented Dec. 3, 1940 UNITED STATES PATENT oFFlcs 1 Claim.

This invention relates to devices for injecting fluent materials into cavities and has particular reference to such a device for injecting materials in powdered form.

It is an object of the invention to provide a syringe which may be produced so economically that the major portion of the device which enters the cavity may be discarded after being used but once without incurring material loss to the user.

Another object of the invention is to provide a syringe in which a component part thereof serves as a package in which correct doses of material to be applied may be dispensed.

The invention possesses other objects and fea- I tures of advantage, some of which, together ,with the fo-regoing, will be speciiically set forth in the detailed description of the invention hereunto annexed. It is to be understood that the invention is not to be limited to the particular species thereof herein shown and described as various other embodiments thereof may be employed within the scope of the appended claim.

Referring to the drawing:

Figure 1 is a side elevational view, partly in vertical section, of the syringe tube showing it used as a dispensing package.

Figure 2 is a side elevational view, partly in vertical section and to a reduced scale, of the complete syringe ready for use showing the tube connected with the fluid pressure generator.

Figure 3 is a View similar to Figure 2 showing a modified form of the invention.

In detail, the invention comprises a short length of tubing 3, preferably constructed of superposed strips of paper or other such material, helically wound on a suitable mandrel. Within the tube is placed a measured charge of dry powdered material 4 and caps 6, which are preferably constructed of gelatin or Celluloid, are forced over each end of the tube so as to retain the material 4 therein. `In order to protect the material 4, which may be soluble, from coming in contact with moisture, the tube 3 is preferably impregnated with a waterprooiing compound such as parailin. The above described combination of elements forms a capsule or package in which the powder 4, pre-apportioned in correctly measured doses depending upon what use the powder is to be put to, may be sold. It is convenient to pack a quantity, for example a dozen, of these capsules in a box or other such container and sell them as a unit together with a suitable pressure generator such as the rubber bulb 'I shown in Figure 2.

(Cl. 12S-266) In using the syringe, the caps 6 are removed from both ends of the tube 3 and the slender spout 3 of the pressure generator is inserted into frictional engagement with one end of the tube. The opposite end of the tube is then inserted into the cavity or opening into which the powder 4 is to be injected and the bulb 'I is suddenly and forcibly collapsed by the hand of the user. This will cause a blast of compressed air to flow out of the central bore 9 of the spout 8 and 10 through the tube, carrying with it the powder contained in the tube. It has been found that a single blast of air is suiiicient to substantially completely evacuate of powder a tube having an internal diameter of ,le of an inch and a length of about four inches. It is quite important that the powder 4 be not of such fine mesh that when it packs in the tube under the action of vibration 1 or shocks imposed on the tube in handling, it will be impervious to the passage of air therethrough since this condition will prevent the powder being quickly and easily blown from the tube.

In Figure 3 I have shown a variant form of my invention. In this construction, the tube II, which contains the measured charge of powder I2, is crimped at its discharge end to provide a restricted opening I3 through which the powder is blown and which-causes the discharge blast to assume an outwardly diverglng conical forni. The usual cap 6 is provided engaging and for closing the discharge end of the tube. The opposite end of the tube is provided with a cupshaped piston I4, which may be constructed of pressed paper or similar inexpensive material, having a peripheral flange I6 which is slightly less in diameter than the internal diameter of the tube and a tubular collar I1 is pressed into the end of the tube and engages the piston I4.

It will be seen that the piston, engaging the collar Il, forms a closure for the end of the tube which serves to retain the powder I2 therein. Thus the structure shown in Figure 3, less the rubber bulb l, forms the package in which the powder is sold. When it is desired to inject the powder, the spout 8 of the bulb is forced into the bore of the collar I'I, the cap I3 is removed from the opposite'end of the tube, and the tube is inserted into the cavity. The bulb 'I is then forcibly squeezed which will cause a blast of air 5o to flow along the tube driving the piston I4 before it. Due to the fact that the piston flange IB is smaller in diameter than the tube bore, quantities of air will iiow past the piston and will stir up and carry quantities of the powder 455 pressed into the opposite end of said tubular package, a hollow cylindrical piston in said tubular package, movable longitudinally thereof and having a peripheral ange of lesser diameter than the innerdiameter of said tubular package which engages an end of said collar so as to close the said opposite end of the tubular package, and a hollow rubber bulb having a spout provided with a discharge orifice, said spoutV being insertible, in frictional engagement, into 10 said collar at said opposite end of the tube.


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US5171219 *Jun 8, 1990Dec 15, 1992Sumitomo Pharmaceuticals Co., Ltd.Pharmaceutical preparation administrator
US5273531 *Sep 21, 1992Dec 28, 1993Knoepfler Dennis JMethod of applying thrombic powder in laparoscopic procedures
US5320257 *Sep 26, 1991Jun 14, 1994John SneddenResilient ampule with articulating linkage and elongate spout
US5328099 *Jun 16, 1993Jul 12, 1994Etablissements ValoisCompressed gas device for spraying a single dose of a fluid substance in finely divided form
US5797392 *Jan 22, 1997Aug 25, 1998Direct-Haler A/SInhaler
US8118777May 26, 2010Feb 21, 2012Cook Medical Technologies LlcSystems and methods for delivering therapeutic agents
US8157772May 8, 2008Apr 17, 2012Cyto-Biotics, LlcMedicament dispensing devices and methods
US8327844Mar 30, 2004Dec 11, 2012Optinose AsNasal delivery method
US8361054Dec 8, 2009Jan 29, 2013Cook Medical Technologies LlcApparatus and methods for containing and delivering therapeutic agents
US8465463Mar 23, 2012Jun 18, 2013Cyto-Biotics, LlcMedicament dispensing devices and methods
US8555877Jun 2, 2006Oct 15, 2013Optinose AsNasal delivery device
US8555878Jun 2, 2006Oct 15, 2013Optinose AsNasal delivery device
US8728032Jan 17, 2012May 20, 2014Cook Medical Technologies LlcSystems and methods for delivering therapeutic agents
EP0575239A1 *Jun 15, 1993Dec 22, 1993ETABLISSEMENTS VALOIS Société Anonyme dite:Compressed gas device for spraying a single dose of fluid material in a finely divided form
EP0843565A1 *Nov 13, 1995May 27, 1998Genentech, Inc.Coarse spray delivery of functional biologic materials
U.S. Classification604/58, 604/192, 604/218, 604/275, 604/217
International ClassificationB05B11/06, A61M3/00
Cooperative ClassificationB05B11/062, A61M3/00
European ClassificationB05B11/06B, A61M3/00