|Publication number||US2307986 A|
|Publication date||Jan 12, 1943|
|Filing date||Feb 15, 1940|
|Priority date||Feb 15, 1940|
|Publication number||US 2307986 A, US 2307986A, US-A-2307986, US2307986 A, US2307986A|
|Inventors||Brown Bolte, Harry Mcneilly|
|Export Citation||BiBTeX, EndNote, RefMan|
|Referenced by (65), Classifications (17)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Jan. 12, 1943.
B. BQLTE Erm.
' INSUFLATOR Fned Feb. v15, 19404 Patented Jan. 12, 1943 UNITED STATES PATENT OFFICE INSUFFLATOR Brown Bolt, Orange, and Harry McNeilly,
Bloomfield, N. J., assig'nors, by mesne assignments, to said Bolt 3 Claims.
This invention pertains to new and useful improvements in powder applicators, particularly of the type generally classified as insuiflators and employed for applying medicaments to cavities of the human body.
In certain cases, it is necessary to effect dilation of the cavity to be treated prior to the application of the medicament thereto and it is the primary object of this invention to provide a novel device of the aforementioned character by which, both dilation of the cavity to be treated and application of the medicament may be accomplished in succession without removing the device from the cavity to be treated.
A feature of the invention resides in a novel construction and arrangement of parts whereby a sealed powder cartridge may be retained intact within the device during the dilation action, and subsequently ruptured in order to discharge from the device the contents of the cartridge for the purpose of applying same to the area to be treated.
A further feature of the invention resides in a novel construction and arrangement of parts whereby air from a common or single source may be employed for the dual purposes of dilating the cavity to be treated and for discharging the contents of the cartridge from the device.
Other features of the invention relate to certain novel and improved constructions, arrangements and combinations of parts hereinafter described and particularly pointed out in the claims, the advantages of which will be readily understood and appreciated by those skilled in the art.
The invention will be clearly understood from the accompanying drawing illustrating the invention in its preferred form -and the following detailed description of the constructions therein shown.
Figure l is a view in elevation of a device constructed in accordance with the present invention illustrating certain of the parts in one position in full lines and in another position in broken or dash lines,
Figure 2 is a longitudinal sectional View, partly broken away and taken substantially on the line 2--2 of Figure l, the figure illustrating in full lines the position of the parts prior to rupturing of the cartridge and in broken or dash lines, a position of the parts during their movement to perform the rupturing of the cartridge,v one end only of which has been shown as having been ruptured,
Figure 3 is a central longitudinal sectional View partly broken away, the figure illustrating the position of the parts after the cartridge rupturing operation has been completed, and;
Figure 4' is a transverse sectional View taken substantially on the lined- 4 of Figure 3.
A device constructed in accordance with the illustrated embodiment of the invention comprises a main body portion 5 which constitutes a cartridge receiving chamber 6, a nozzle 1 which may or may not carry a conventional shield 8, and a conventional air compressing bulb 9.
The main body portion 5 preferably consists of two sections I0 and Il detachably connected together by a. threaded connection I2, the said sections being so constructed that when they are secured together, they form the cartridge receiving chamber heretofore referred to. The threaded connection l2 permits of separation of the sections l0 and Il in order that a cartridge such as designated I3 in the drawing may be positioned within the chamber 6.
The nozzle 'l is shown as removably attached to the section 5 by a threaded connection I4 but obviously, the nozzle could be detachably connected t0 the section I0 by other means or may be an integral extension thereof, as desired.
Leading through the section It, there is a passage I5 which constitutes the discharge passage of the chamber 6 and which has communication with a passage IS leading through the nozzle l. The inner end of the passage i5 terminates in a conical projection I1 which projects into the chamber E and which is formed upon its inner end with laterally extending ports I 8 which extend entirely through the side walls of the conical projection I'I, but preferably do not extend throughout the length thereof.
Sldably mounted in the section Ii, there is a plunger 20 which is slidably mounted in a bearing 2| preferably in the form of a flange projecting inwardly of the member I E. The plunger 20 has a passage 22 extending therethrough and extending from the inner end of the plunger 20, there is a conical projection 23 through which the passage 22 also extends. rlhe conical projection 23 is provided with a plurality of laterally extending ports 24 similar to the ports I3 heretofore mentioned which ports 2t establish communicaton between the chamber 6 and the passage 22. The section Il is provided in its outer end with an internally threaded recess 25, the purpose of which will be hereinafter more speciiically set forth. i
The plunger 20 has a reduced extension 26 by which it: is slidably mounted in the bearing 2|` heretofore mentioned and the free end of this extension 26 is externally threaded as at 27.
The reference character 28 designates a combined coupling and locking member which serves to couple the compressible bulb 9 to the plunger 20 and also to lock the plunger 20 against movement in the chamber 6 under certain operating conditions which will be hereinafter described.
This member 23 comprises a flange-like body portion 39 from one face of which extends an externally threaded projection 3l for threaded engagement with the internally threaded recess 25 in the end of the section I I. Projecting from the opposite face of the body portion II, there is a nipple extension 32 to which the bulb 9 is attached.
Leading through the nipple extension 32 there is a passage 33, the inner end of which is enlarged as at 34 to provide a valve seat 35. The
enlarged portion 34 of the passage 33 provides a housing for a ball valve 36 which is retained in the housing by the threaded end of the extension 2B when the several parts are assembled.
That end of the reduced extension which retains the ball valve 36 in its housing, is provided with ports 3l which permit of passage of air from the enlarged portion of the passage 33 when the ball valve is in engagement, with the end lof the reduced extension. However, when the ball valve is in engagement with the seat 35, passage of air through the passage 33 in the direction of the bulb 9 is prevented. rThus a check valve which will permit of the free passage of air from the bulb 9 to the cartridge chamber 6, but which will prevent passage of air from the cartridge chamber E to the bulb 9, is provided.
The operation and manner of use of the device will now be described.
The sections le and li are separated and a cartridge I3 is placed within one of the members after which they are connected together with the cartridge in the chamber 6.
The cartridge I3 is of a type which has frangible or rupturable end walls and is preferably of such diameter as to iit snugly against the side walls of the chamber 3 and of such length, that when the parts are adjusted to the full line position shown in Figure 2, the co-nical projections I1 and 23 will engage their respective end walls of the cartridge but without rupture thereof.
To adjust the parts to the full line position shown in Figure 2, the combined coupling and locking member 23 is backed out of threaded engagement with the threaded recess 25 and the plunger is moved in the bearing 2l.
It is understood that the fit o-f the reduced extension 29 of the plunger with the bearing 2l is of the type known as friction nt and will be sufcient to retain the plunger against movement under normal operating conditions.
The several parts are illustrated in the position just described in full lines in Figure 2 of the drawing and in this position of the parts, the device is in condition for the performance of the dilation operation which will now be described.
'I'he nozzle member 'I is inserted into the cavity to be treated after which the bulb 9 is subjected to a series of compressions to force air through the passage 33, the passage 22 of the plunger, from which it is discharged into the chamber 6 through the lateral ports 21! of the conical projection 23.
The air is adapted to be by-passed around the cartridgeV I3 to the-lateral ports I8 of the conical projection l1 through which ports I 8 it passes to the passages I5 and I6 to be discharged from the nozzle member into the cavity to be treated to dilate the same.
It will be remembered that the cartridge I3 was described as being of such a diameter as to fit snugly within the chamber B and to provide for by-passing air around a cartridge of this type, channels 40 extend longitudinally of the inner face of the wall of the chamber 6 which channels extend substantially throughout the length of the said chamber 6.
After the dilation operation has been completed and it is desired to apply the contents of the cartridge I3 to the inner walls or surfaces of the cavity, without removing the nozzle of the instrument from the cavity, the `combined coupling and locking member 28 is moved to the broken line position shown in Figure 2, the plunger 20 sliding in the chamber 6.
The sliding movement of the plunger just described exerts endwise pressure upon the cartridge and moves it longitudinally of the chamber 6. This longitudinal movement of the cartridge 6 results in the rupturing of one end wall thereof. Which of the end walls will be the first to rupture is problematical and while in Figure 2 the end wall of the cartridge adjacent the nozzle end of the instrument has been illustrated as the ruptured end, this showing is merely an arbitrary one and it may in some instances happen that the opposite end of the cartridge would be the rst to rupture.
In either case, however, the combined coupling and locking member moves to the broken line position shown in Figure 2 in which position its threaded extension is in position for threaded engagement with the threaded recess 25. In this last mentioned position, the member 23 is rotated in a clock-wise direction which by reason of its threaded engagement with the thread of the recess 25, moves the plunger 20 still further into the chamber 6 to effect a rupturing of that end of the cartridge which was not ruptured by the first mentioned operation.
When the member 23 has been screwed home, in which position it is illustrated in Figure 3, the rupturing of both ends of the cartridge has been completed as illustrated in said figure.
.'By reference to Figure 3 of the drawing it will be noted that the conical projections I'I and 23 have passed into their respective ends of the cartridge and that the ends of the cartridge seat tightly against their respective conical projections in such a manner that the conical projections completely close the ends of the cartridge. In this position of the parts, the ports I8 and 24 are completely within the catridge and the bypass channels 4l! are completely cut oi. If now the bulb 9 be compressed, air is discharged from the passage 22 directly into the cartridge I3 forcing its contents through the passage I6 of the discharge nozzle from which the contents of the cartridge are discharged into the cavity to be treated.
From the foregoing it will be apparent that the present invention provides a device by means of which a cavity may be dilated, dilation of the cavity maintained and a medicament applied to the surfaces of the cavity to be treated Without necessitating removal of the instrument after it has been once positioned within the cavity.
While the invention has been herein illustrated in its preferred form, it is to be understood that it is not to be limited to the specic construction herein employed and that such modiiications of construction as rightfully fall within the purview of the appended claims may be resorted to without departing from the spirit of the invention.
Having thus described the invention what is claimed as new is:
l. In a device of the character described, a cartridge receiving chamber having an air discharge passage leading from one end thereof, a projection extending inwardly of the discharge end of the chamber, and through which the air discharge passage extends, ports extending laterally of Said -projection for establishing communication between the air discharge passage and the interior of the chamber, a plunger movable longitudinally of the chamber, means for moving the plunger in the chamber, a projection extending from the inner end of the plunger and forming in combination with said aforementioned projection when the plunger is in one position, means for positioning a cartridge within the chamber and in an advanced position of the plunger, means for rupturing the opposite ends of a cartridge within the chamber, an air inlet for the chamber, said air inlet extending through the plunger and projection thereof, and ports extending laterally of the projection of the plunger for establishing communication between the air inlet passage and the interior of the chamber, and means for by-passing -air around a cartridge in the chamber when the plunger is in its cartridge positioning position, said air by-passing means being cut olf when the plunger has been moved to its cartridge rupturing position.
2. In a device of the character described, a cartridge receiving chamber having an air discharge passage leading from one end thereof, a tapered projection extending inwardly of the discharge end of the chamber, and through which the air discharge passage extends, ports extending laterally of the inner end of said projection for establishing communication between the air discharge passage and the interior of the chamber, a plunger movable longitudinally of the chamber, means for moving the plunger in the chamber, a projection extending from the inner end of the plunger and forming in combination with said aforementioned projection when the plunger is in one position, means for positioning a cartridge and holding the same against movement within the chamber and in an advanced position of the plunger, means for rupturing the opposite ends of a cartridge within the chamber, an air inlet .for the chamber, said air inlet extending through the plunger and the projection thereof, and ports extending laterally of the projection of the plunger for establishing communication between the air inlet passage and the interior of the chamber, and means for by-passing air around a cartridge in the chamber when the plunger is in its cartridge positioning position, said air by-passing means being out off when the plunger has been moved to its cartridge rupturing position.
3. In a device of the character described, a cartridge receiving chamber having air channels extending longitudinally of the inner face of the walls thereof, an air discharge passage leading from one end thereof, a projection extending inwardly of the discharge end of the chamber, and through which the air discharge passage extends, ports extending laterally of said projection f-or establishing communication between the air discharge passage and the interior of the chamber, a plunger movable longitudinally of the chamber, a projection extending from the inner end of the plunger and cooperating with said aforementioned projection when the plunger is in one position to provide means for positioning a cartridge within the chamber and When the plunger is in an advanced position to provide means for rupturing the opposite ends of a cartridge within the chamber', an air inlet for the cham-ber, said air inlet extending through the plunger and the -projection thereof, and ports extending laterally of the projection of the plunger for establishing communication between the air inlet passage and the interior of the chamber, the channels of the cartridge receiving chamber forming means for `lay-passing air around a cartridge in the chamber when the plunger is in its cartridge positioning position, said air .by-passing means being cut 01T when the plunger has been moved to its cartridge rupturing position.
BROWN BOLT. HARRY M CNEILLY,
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US2501279 *||Feb 8, 1946||Mar 21, 1950||Lazar Kark Charles||Means for spraying or projecting powder|
|US2519555 *||Aug 31, 1945||Aug 22, 1950||Abbott Lab||Sterile medicament insufflator cartridge and insufflator|
|US2549303 *||Apr 20, 1949||Apr 17, 1951||Bristol Lab Inc||Inhaler for crystalline pencilllin or the like|
|US2672144 *||Nov 19, 1951||Mar 16, 1954||Cohen Milton J||Powder dispenser|
|US2992645 *||Mar 26, 1959||Jul 18, 1961||Benger Lab Ltd||Disperser for powders|
|US3155573 *||Feb 26, 1959||Nov 3, 1964||Benger Lab Ltd||Inhalant composition and method of making same|
|US3400714 *||May 3, 1965||Sep 10, 1968||Brunswick Corp||Nasal cannula|
|US3906950 *||Apr 2, 1974||Sep 23, 1975||Isf Spa||Inhaling device for powdered medicaments|
|US3998226 *||Sep 22, 1975||Dec 21, 1976||Edward G. Gomez||Inhalation device for encapsulated concentrates|
|US4338931 *||Apr 28, 1980||Jul 13, 1982||Claudio Cavazza||Device for the quick inhalation of drugs in powder form by humans suffering from asthma|
|US5273531 *||Sep 21, 1992||Dec 28, 1993||Knoepfler Dennis J||Method of applying thrombic powder in laparoscopic procedures|
|US5562918 *||Sep 1, 1993||Oct 8, 1996||Bespak Plc||Drug dispensing system|
|US5683361 *||Mar 31, 1994||Nov 4, 1997||Novo Nordisk A/S||Disposable dispenser for powder|
|US6168587||Dec 5, 1997||Jan 2, 2001||Powderject Research Limited||Needleless syringe using supersonic gas flow for particle delivery|
|US6866039||Sep 12, 2001||Mar 15, 2005||Bespak Plc||Dispensing apparatus|
|US6881200 *||Feb 10, 1999||Apr 19, 2005||Powderject Research Limited||Needleless syringe using super sonic gas flow for particle delivery|
|US6945953||Jan 21, 2003||Sep 20, 2005||Bespak Plc||Dispensing apparatus for delivering powdered product|
|US7086571||Apr 17, 2002||Aug 8, 2006||Bespak Plc||Valves for pressurized dispensing containers|
|US7270127||Sep 3, 2002||Sep 18, 2007||Becton, Dickinson And Company||Medicament respiratory delivery device|
|US7618394||Nov 17, 2009||Powderject Research Limited||Needleless syringe using supersonic gas flow for particle delivery|
|US7832399 *||Nov 16, 2010||One Dose, Llc||Medication inhaler|
|US7861712||Apr 23, 2004||Jan 4, 2011||Manta Product Development||Sealed capsule including an integrated puncturing mechanism|
|US7913329 *||Jul 25, 2002||Mar 29, 2011||Graham Hubert Smith||Anal cleaning device|
|US7942846||Aug 31, 2007||May 17, 2011||Powderject Research Limited||Needleless syringe using supersonic gas flow for particle delivery|
|US8061006||Jul 25, 2002||Nov 22, 2011||Powderject Research Limited||Particle cassette, method and kit therefor|
|US8118777||May 26, 2010||Feb 21, 2012||Cook Medical Technologies Llc||Systems and methods for delivering therapeutic agents|
|US8342176||Dec 20, 2010||Jan 1, 2013||Manta Devices, Llc||Sealed capsule including an integrated puncturing mechanism|
|US8361054||Dec 8, 2009||Jan 29, 2013||Cook Medical Technologies Llc||Apparatus and methods for containing and delivering therapeutic agents|
|US8540665||Nov 4, 2009||Sep 24, 2013||Powder Pharmaceuticals Inc.||Particle cassettes and processes therefor|
|US8550074||Jan 15, 2010||Oct 8, 2013||Manta Devices, Llc||Delivery device and related methods|
|US8607787||Oct 9, 2012||Dec 17, 2013||Manta Devices, Llc||Dose delivery device for inhalation|
|US8627818||Dec 28, 2012||Jan 14, 2014||Manta Devices, Llc||Sealed capsule including an integrated puncturing mechanism|
|US8728032||Jan 17, 2012||May 20, 2014||Cook Medical Technologies Llc||Systems and methods for delivering therapeutic agents|
|US8763605||Jul 20, 2006||Jul 1, 2014||Manta Devices, Llc||Inhalation device|
|US9004064||Oct 7, 2013||Apr 14, 2015||Manta Devices, Llc||Delivery device and related methods|
|US9044546||Aug 22, 2013||Jun 2, 2015||Powder Pharmaceuticals Incorporated||Particle cassettes and processes therefor|
|US9101744||Dec 21, 2012||Aug 11, 2015||Cook Medical Technologies Llc||Systems and methods for delivering therapeutic agents|
|US9283336||Sep 18, 2012||Mar 15, 2016||Manta Devices, Llc||Delivery device and related methods|
|US9358338||Apr 28, 2015||Jun 7, 2016||Powder Pharmaceuticals Incorporated||Particle cassettes and processes therefor|
|US9375533||Jul 8, 2015||Jun 28, 2016||Cook Medical Technologies Llc||Systems and methods for delivering therapeutic agents|
|US20020144678 *||Jan 17, 2002||Oct 10, 2002||Warby Richard John||Drug delivery devices|
|US20030047184 *||Sep 3, 2002||Mar 13, 2003||Lockhart Artis R.||Medicament respiratory delivery device|
|US20030178440 *||Jan 21, 2003||Sep 25, 2003||Bespak Plc||Dispensing Apparatus for Delivering Powdered Product|
|US20030178448 *||Apr 17, 2002||Sep 25, 2003||Warby Richard John||Valves for pressurized dispensing containers|
|US20030192917 *||Feb 13, 2003||Oct 16, 2003||Bespak Plc||Valves for Dispensers|
|US20040216224 *||Jul 25, 2002||Nov 4, 2004||Smith Graham Hubert||Anal cleaning device|
|US20050143675 *||Jun 2, 2004||Jun 30, 2005||Home Diagnostics, Inc.||Integrated diagnostic test system|
|US20050165348 *||Dec 9, 2002||Jul 28, 2005||Bellhouse Brian J.||Needleless syringe using supersonic gas flow for particle delivery|
|US20050238708 *||Apr 23, 2004||Oct 27, 2005||Andrew Jones||Sealed capsule including an integrated puncturing mechanism|
|US20050279352 *||Aug 29, 2005||Dec 22, 2005||Bespak Plc||Drug delivery devices|
|US20070221216 *||Mar 9, 2007||Sep 27, 2007||Ganem Charles F||Medication inhaler|
|US20080006269 *||Aug 21, 2007||Jan 10, 2008||Lockhart Artis R||Medicament Respiratory Delivery Device|
|US20080300535 *||Feb 20, 2008||Dec 4, 2008||Powderject Research Limited||Particle cassette, method and kit therefor|
|US20100121262 *||Nov 4, 2009||May 13, 2010||Lee's Pharmaceutical (Hk), Ltd.||Particle cassettes and processes therefor|
|US20100160897 *||Dec 8, 2009||Jun 24, 2010||Ducharme Richard W||Apparatus and Methods for Containing and Delivering Therapeutic Agents|
|US20100180894 *||Jul 22, 2010||Andrew Jones||Delivery device and related methods|
|US20110083668 *||Apr 14, 2011||Manta Devices, Llc||Sealed capsule including an integrated puncturing mechanism|
|USRE43824||Jan 11, 2002||Nov 20, 2012||Powder Pharmaceuticals Inc.||Needleless syringe|
|EP1917992A2 *||Sep 15, 1995||May 7, 2008||Nektar Therapeutics||Apparatus and methods for dispersing dry powder medicaments|
|WO1992006727A1 *||Oct 11, 1991||Apr 30, 1992||Novo Nordisk A/S||Disposable dispenser for powder|
|WO1994005358A2 *||Sep 1, 1993||Mar 17, 1994||Medix Limited||Drug dispensing system|
|WO1994005358A3 *||Sep 1, 1993||May 11, 1994||Drug dispensing system|
|WO2002055133A3 *||Jan 9, 2002||Nov 14, 2002||Becton Dickinson Co||Medicament respiratory delivery device, cartridge and method of making same|
|WO2002056950A3 *||Jan 9, 2002||Oct 24, 2002||Becton Dickinson Co||Medicament respiratory delivery device|
|WO2002060517A3 *||Jan 9, 2002||Nov 7, 2002||Becton Dickinson Co||Medicament respiratory delivery device and method|
|U.S. Classification||604/58, 604/217, 604/278, 604/201, 604/218|
|International Classification||A61M15/00, A61M13/00, B05B11/06|
|Cooperative Classification||A61M13/00, A61M2205/075, A61M15/0028, B05B11/062, A61M2202/064, A61M2015/0036|
|European Classification||A61M15/00C, A61M13/00, B05B11/06B|