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Publication numberUS2415871 A
Publication typeGrant
Publication dateFeb 18, 1947
Filing dateSep 18, 1945
Priority dateDec 7, 1944
Publication numberUS 2415871 A, US 2415871A, US-A-2415871, US2415871 A, US2415871A
InventorsDe Woody Charles M
Original AssigneeAce Glass Inc
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Container for aseptic filling and dispensing of sterile liquids
US 2415871 A
Abstract  available in
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Claims  available in
Description  (OCR text may contain errors)

Feb; 18, 19-47. c, D WOODY 2,415,871

CONTAINER FOR ASEPTI C FILLING AND DISPENSING OF STERILE LIQUIDS Original Filed Dec. 7, 1944 wto wmp Patented Feb. 18, 1947 CONTAINER FOR ASEPTIC FILLING AND DISPENSING or STERILE LIQUIDS Charles M. De Woody, Vineland, N. J assignor to Ace Glass Incorporated, Vineland, N. J a corporation of New Jersey Original application December 7, 1944, Serial No. 567,094. Divided and this application September 18, 1945, Serial No. 617,119 v Claims. 1

This invention relates to a container for aseptic filling and dispensing of sterile liquids, and the present application is a division of my parent application, Serial No. 567,094, filed December 7, 1944.

Many types of closures have been used for containers of sterile liquids. However, those fluids which are not adaptable to heat sterilization present special problems. Containers for such materials or fluids must be sterilized before filling and maintained sterile. Strict aseptic manipulation must be observed throughout, particularly with those fluids which are intended for human consumption either by mouth or by injection.

Heretofore, containers for such purposes have been proposed and used to some extent but they have disadvantages. The primary object of the present invention is to provide a container adapted particularly for use with fluids which are not heat sterilizable, that is, fluids which would decompose, congeal, etc., under the influence of sterilizing heat, and one which eliminates the objectionable features of the devices heretofore proposed.

With the foregoing object outlined and with other objects in view which will appear as the description proceeds, the invention consists in the novel features hereinafter described in detail, illustrated in the accompanying drawing and more particularly pointed out in the appended claims.

In the drawing:

Fig. l is a vertical sectional view of a container in accordance with the invention.

Fig. 2 is a top plan view with the cap removed.

Fig. 3 is a top plan view of the cap.

Fig. 4 is a perspective view of a washer or gasket employed in the construction shown in Fig. 1.

Fig. 5 is a vertical sectional view of the top portion of a container and illustrating another modification.

Referring to the embodiment illustrated in Figs. 1 to 4, inclusive, II designates the body of a container made of glass or any other suitable material, provided at its upper end with a top i 2 having a center hole l3 and an off-center hole Hi, the latter being preferably counter-bored. Rising from the top is a neck l5 having at the exterior thereof a coarse pitched screw thread l6.

' to seal oil the air vent 31.

cap flange has an orifice 23 designed to register with the hole 14 when the cap is in a certai position relatively to the container.

24 designates a resilient washer of rubber or the like, having a central hole 25 for the reception of the neck of the bottle. A plug 26 fits in the hole 14 of the container. A tongue and groove joint 21 may be provided between the plug and the wall of the hole M for sealing purposes, and the washer has an indication or indentation 28 immediately above the center of the plug, serving as a guide for the insertion of a hypodermic needle or the like.

The hole I3 is closed substantially by a second plug 29 secured in position by a tongue and groove joint 30, and this plug has an air vent 3!. The plug Z Q is also preferably formed of rubber or the like and has a cavity 32 in the top thereof for the reception of a frustro-conical stopper 33 formed of resilient material, such as rubber, and grasping an annular flange 34 at the lower end of a tubularture 35 which depends from the top 18 of the cap and is provided with a tapered bore 36.

When the parts are in the positions shown in Fig. 1, an annular crown cap 31 may be employed to interlock the flange of the cap with an annular bead 38 at the top of the bottle.

Before filling the bottle, the screw cap I? is loosely engaged on the neck of the bottle so that the stopper 33 does not contact the bottle above the plug 29, leaving the air vent 3i open. Similarly, there is no pressure upon the washer 23 so that slight pressure within the bottle will cause the plug or button 26 to rise to permit the escape of air from the container during filling.

the needle is withdrawn and the screw cap tighened, pressing together stopper 33 and lug 29 Because of the resiliency and wedging action of 33 and 29, the needle perforations are satisfactorily sealed in tightening the screw cap. In the tightening operation, the hole 23 in the flange of the cap moves out of registration with the hole I 4 and therefore the flange will bear upon the resilient washer to effectively seal the hole l4. Afterwards, as a precau tionary measure, a crown cap 31, of conventional design with the center removed, may thenhbe slipped over the cap flange Hi to prevent unscrewing of the cap.

In dispensing the sterile liquid within the container, the crown cap is removed and the screw 1 cap loosened until the hole 23 i the cap flange is centered above the plug 26. A'sterile dispensing needle is then inserted at indentation 28 through the washer and plug 26. The unscrew ing of the cap causes the stopper 33 to be lifted free of plug 29, and the constricted portion of the center neck of the container, thus removing the obstruction from vent 3|, which now acts as an air inlet.

By virtue of the high resiliency of the parts 29 and the holes punctured in them by the filling device remain closed so that the air which is admitted into the bottle must follow the less re sistant path along the loosely fitting screw threads and so into the container.

Tubes d2, d3 are connected to either one or both of the plugs 29 and 26, as illustrated in Fig. 1. These tubes need not be straight as'shown, but may be bent to reach any point in the interior of the bottle, and may be used either as vent or delivery tubes.

In the embodiment illustrated in Fig. 5, the hole 13a is counter-bored so as to provide an annular edge 1327 designed to contact with the conical face I30 of the stopper 22a. With thi construction the plug 29 is eliminated and a single plug or stopper serves the same purpose. Also in this embodiment the plug or button 26a is shown as a part separate from the washer 24a but serving the same purpose as the combined washer and button ensemble. In this construction the washer has 8. depending nipple 24b projecting into-a cavity in the top of the button 26a.

While I have disclosed what I now consider to be some preferred embodiments of the invention in such manner that the same may be readily understood by those skilled in the art, I am aware that changes may be made in the detail without departing from the spirit of the invention as expressed in the appended claims.

What I claim and desire to be secured by Letters Patent is: i

1. A receptacle of the character described having a top provided with a central opening and an off-center opening, a neck extending upwardly from the top and provided with a screw thread, a cap having threaded engagement with said screw thread and provided with a base flange extending over said eff-center opening, said flange .having an opening designed to register with said ofi-center opening when the cap is in a predetermined position, a washer arranged between said flange and the top of the receptacle, a plug normally closing said off-center opening and adapted to be held in closed position by the washer and flange, a tubular member connected to the cap and extending into the bottle neck, a closure for the central opening including a stopper carried by said tubular member, and a vent or delivery tube secured to said closure and extending downwardly into the receptacle.

2. A receptacle of the characterdescribed having a top provided with a central opening and an ofi-center opening; a neck extending upwardly from the top and provided with a screw thread, a cap having threaded engagement with said screw thread and provided with a base flange extending over said offeenter opening, said flange having an opening designed to register with said off-center opening when the cap is in a predetermined position, a washer arranged between said flange and the top of the receptacle, a plug normally closing said oil-center opening and adapted to be held in closed position by the washer and flange, a tubular member connected to the cap and extending into the bottle neck, a closure for the central opening including a topper carried by said tubular member, and a vent or delivery tube projecting downwardly from said plug into the receptacle.

3. A receptacle of the character described having a top provided with a central opening and an oil-center opening, a neck extending upwardly from the top and provided with a screw thread, a cap having threaded engagement with said screw thread and provided with a base flange extending over said off-center opening, said flange having an dpening designed to register with said oil-center opening when the cap is in a predetermined position, a washer arranged between said flange and the top of the receptacle, a plug normally closing said ofi-center opening and adapted to beheld in closed position by the washer and flange, tubular member connected to the cap and extending into the bottle neck, the top of the receptacle having at least one annular edge at the central openings, and a stopper of puncturable material carried by the tubular member and provided with a substantially conical face adapted to cooperate with said edge to close the central opening.

4. A receptacle of the character described having a top provided with a central opening and an oil-center opening, a neck extending upwardly from the top and provided with a screw thread, a cap having threaded engagement with said screw thread and provided with a base flange extending over said off-center opening, said flange having an opening designed to register with said Offt pe ing when the cap is in a predetermined position, a washer arranged between said flange and the top of the receptacle, a plug separate from said washer, normally closing said oncenter opening and adapted to be held in closed position by thewasher and flange, interlocking means between the washer and plug to prevent the washer from turning relatively to the plug, a tubular member connected to the cap and extending into the bottle neck, and a closure for the central opening including a stopper carried by said tubular member.

5. A receptacle of the character described having a top provided with a central opening and an off-center opening, a, neck extending upwardly from the top and provided with a screw thread, a cap having threaded engagement with said screw thread and provided with a base flange extending over said cit-center opening, said flange having an opening designed to register with said off-center opening when the cap is in a predetermined position, a washer member arranged between said flange and the top of the receptacle,

,a plug member separate from the washer member, normallyclosing said off-center opening and adapted tobe held in closed position by the flange, one of said members having a cavity and the other. having a nipple extending into the cavity, a tubular member connected to the cap and extending into the bottle, and a closure for the central opening includin a stopper carried by said tubular member.

CHARLES M. DE WOODY.

, REFERENCES CITED The following references are of record in the file of this patent:

UNITED STATES PATENTS Number Name Date 2,388,634. De.Woody Nov. 6, 1945

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2388634 *Dec 7, 1944Nov 6, 1945Ace Glass IncContainer for aseptic filling and dispensing of sterile liquids
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US2653610 *Oct 28, 1950Sep 29, 1953Arthur E SmithDispensing closure
US2667873 *Aug 24, 1950Feb 2, 1954Hein Jr George NAmpoule
US4505709 *Feb 22, 1983Mar 19, 1985Froning Edward CLiquid transfer device
US4676788 *Nov 27, 1985Jun 30, 1987E. I. Du Pont De Nemours And CompanyGuide member for a vial
US20050078759 *Aug 26, 2004Apr 14, 2005Interdigital Technology CorporationSubcarrier and bit allocation for real time services in multiuser orthogonal frequency division multiplex (OFDM) systems
US20130053815 *Aug 21, 2012Feb 28, 2013Allergan, Inc.High recovery vial adaptor
US20160151241 *Dec 28, 2015Jun 2, 2016Allergan, Inc.High recovery vial adaptor
Classifications
U.S. Classification604/415
International ClassificationB65D51/00
Cooperative ClassificationB65D51/002
European ClassificationB65D51/00B