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Publication numberUS2456001 A
Publication typeGrant
Publication dateDec 14, 1948
Filing dateJan 9, 1946
Priority dateJan 9, 1945
Publication numberUS 2456001 A, US 2456001A, US-A-2456001, US2456001 A, US2456001A
InventorsEmrys Jones George
Original AssigneeEmrys Jones George
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Hypodermic ampoule syringe
US 2456001 A
Abstract  available in
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Claims  available in
Description  (OCR text may contain errors)

Dec. 14, 1948. cs.r E. JONES Y2,456,001'

` y HYPODERMIG AMPOULE SYRINGE FiledJ-an; 9, 194e 'chamber is' formed'which, y lcompletely encloses the part for supporting the "a transverse 'envelope beneath the diaphragm 2 contains the Aliquidfwhich isV to be injected, and immediately above the diaphragm in f element 3 the cylindrical base portion 3a of which -away from' said mount isopen. Figure 1 the needle 5 Tin the upper portion needle inverted and inserted in the borehole 4 of the nozzle element 3 so that the operativeend ofA Patented Dec. 14, 1948 g .sT-Ares PATENT OFFICE vfinalisation In England A January 9, 1946, serial No. 640,027 Greaturitan January 9, 1945 i 7 cieims. (ci. lesa-215) This invention relates to hypodermic ampoule syringe constructions ofthe unitary kind. Such constructions usually comprisera collapsible tube,

"onfwhich the hypodermic needle is mounted.

The object ofthe presentinvention isrto Iensure that during. the storage' stage; theV needle .or the ypart for supporing itis sealed against contamination from outside sources and that oncethe seal is destroyed it cannot be restored. The inven- 1 tion inits broadest as-pect consists in rproviding with an extension so that a the collapsible tube in the storage state,

vneedle with' or without the needle itself.

f 4In order that the invention may be the more clearlyunderstood a syringe in accordance there- `with will now be described, reference being made to the 'accompanying` drawings, wherein:

Figurel` is a sectional elevation of the'syringe f in the storage state.`

"an integral tubular envelope of say sof-t'v metal la. and Ib by means of two portions 'divided into diaphragm 2. The portion laof said the portion Ibis a *nozzle abuts against the diaphragm and'is sealed al] 'f' around the wall of the envelope. The upper portion of said nozzle element forms a nozzle `coaxial An axial bore hole-'4 passes the nozzle element 3-from the with the envelope. completely through *base end to the nozzle end thereof.

The hypodermic needle5 has its base eridsealed j in one closed end of a hollow more-oriless'r cylinsaid needle rests against the diaphragm v2. In

` this positionthe mount 6 will be held clearA of the nozzle portion of the nozzle element asshown.

v-lietween the base portion 3a and the-*nozzle portion of the ,nozzle element 3, said nozzle element is formed with an annular ledge or shoulder 3b (Figure 2) and a tube 1 of say glass, with one end openand the other end closed, is arranged in an inverted state over the nozzle portioni.and theprojectingneedle and mount, with its 7rim resting on the ledge or shoulder 3b. Thefitfof the tube 1 over the upper portion of the nozzle element may be quite loose, and the fit` of ythe needle 5 in the bore hole 4 is also quite loose, but the dimensions are such that the tube 'I isretained more-or-less in place by the upper portion Ib ofthe envelope, and the needle is retained in the bore hole by the tube 1. No amount of shaking will cause the needle to puncture the diaphragm 2, and the glass-tube Tprotects the container portion Ib against collapse.

It will be seen that the needle is completely enclosedl in the sealed upper portion lb and that,

Y. vided between said two portions.

however long the device may be kept before use, the needle must remain sterile. In like manner the liquid to be injected is completelyenclosed in the hermetically sealed lower portion la and must always remain sterile. When the device is to be used,- the upper portion Ib is held between the fingers and squeezed against the tube 1 and is then torn off and removed together with the tube. Subsequently the needle 5 is first pressed down so as to puncture the diaphragm 2 and make a way of communication for the liquid to passup the hole 4, and said needle is then removed from .the hole 4 and the inverted mount 6 is force-fitted on the nozzle portion of the element 3 as shown in Figurei4. Thus, when the envelope portion la is squeezed, the liquid is forced through the borehole 4, through the holderv 6 and up the bore of the needle.

' Turning now to Figure 2, which shows the Way in which the device is constructed, it will rbe seen that the envelope is rst made with its upper endthat is the end of the portion lla-open.' Moreover the portion lb is of slightly larger diameter than the portion la so that a shoulder lc is pro- Moreover the diaphragm 2 is in the form of aninverte'd pill box, having an annular wall 2a which upstands from the perimeter of the diaphragm proper. In construction the diaphragm 2 is rst iittedron to the base portion 3a of the nozzle element `3 and the two parts are together slid into the upper envelope portion |-b so that the diaphragm proper rests on the shoulder Ic, and the wall 2a of said diaphragm fits within the wall of said envelope portion Ib'. i The Vdiaphragm and nozzle are then tightly clamped inplace by means of a clamping element 8. This clamping element consists of a sleeve with one end 8a slightly inturned and it is slid up the container portion I a, with its inturned end lowermost (the aperture within the inturned end being large enough for this) until said inturned end seats against the under side of the shoulder Ic. The dimensions are such that, in this position, the wall oflthe'zenvlope portion "'I b andlth'e wall portion 2a"of the diaphragm are tightly clamped between the sleeve 8 and the base portion 3a of the nozzle element. base portion may be slightlyrconed-fto,` enhance this effect.

The needle and its mount-,l-andralsof'thetube `'I are then placed in position as described, 'and`V finally the upper end of thecenvelopepontion -Ib is closed and sealed by bringing l"xthe'top wedges together, clamping them and hermeticallyseal-` ing, if necessary, by dipping into solder of`low melting point. The Ineedle mount 6 and the --Jntz'alfe element 3 may be of plasticv material. Y A{In-'somecases the usery of the device'fwill him- "'#slflhave asupply of sterile hypodermicneedles andmay thereforey not requirel a hypodermic needletofbefsupplied with the device. To meet the requirements offsuchy cases the needle, togeth 3r Y'=with`-its mount'-an'd also the tube l, maybe --fomitted. 'The-'envelope p-ortion-lbwillbe sealed f-^as`beforeand thus yit will be ensured that the 'wh'ole of fthenozzleelement 3 will be kept sterile. Theuserfwilli-tear'oii the portionv Ib as before andwill then'puncture the diaphragm-'with his l'own sterile nee`dle^ which he will f then V'mount on ff'thenozzle element. "The device without the nee- Ldlecanobviouslybe-'supplied at a reduced cost.

It is to be understood that 'theneedle may be -'=permanently falixedY in place, in which case, after ithe'portion `Ib is ruptured, the diaphragm would "ffbeipuncturled by means-"efr a stiletto passed down 17thefboreof the needle.

' fI olla-im:

LLL-Af hypodermicampoule syringe construction, @comprising anelongated integral one-piece sealed ffenvelope, Isai'denvelope'being of two dilerentfdie aineters'y with.' ani annular shoulder betweenthem, afseiparate `fluid outlet nozzle having an inlet 1 side* 'and an-'outl'et side and a bore through which sflu'idfisfadapted to fpass from-said inlet vside to rfisaid outlet iside.- said no-zzle'tting within the Y argeridiameter portion'of said'envelope with its -ssinl'etnsidelresting against said shoulder, and :.therebyftdividing saidenvelope into' a compartment ofszlargerdiameterand a compartment of f:similiaradiain'eter,v the compartment of smaller ftdiam-eter formingffa'collapsible container for thefluid to be ejected and the compartment 'of the `larger'diameters"forming a hermetically sealed fafenclosure;forthe^outlet side of said nozzle, `and A.1a :separate Yclampingsleeve surrounding said* en- -elopeand clamping the same aroundsaidf nozzle 'z he.venvelope :being adapted to `be-fruptured to expose ther 'outlet' side- .ofy said nozzle.

'2;-rAf hypodermic kampoule syringe construction, ,sco'mprisingan 'elongated integral one-piece'vsealed -nenvelopefsaid:envelopebeing of two diierentl :diameters -with--a'n annular shoulder between them, al separate fluid outlet-Lnozzle having an #inlet sideand an' outletside anda bore through #which iiu-idis adapted to pass from said inlet'side tato said-.outlet sida-said nozzleltting within the largerdiameterportion of said-envelope withits inlet #side resting against Said-sl'wulder,v and thereby dividing said envelope into a compartsiiment for? larger .diameter s .and ia compartment of isniallerzzdiameter, .':the;;compartment. :ofcsmailer If desired the said sleeve and' 4 diameter forming a collapsible container for the fluid to be ejected and the compartment of larger diameter forming a hermetically sealed enclosure for the outlet side of said nozzle, and a separate 5 clamping sleeve with' one end inturned, said clamping sleeve surrounding the larger diameter portion of the envelope, with its inturned edge engagingithe'outsideo the shoulder :and thereby V'clampinglthe envelope around said-nozzle, the l0 envelope being adapted to be ruptured to expose the outlet side of said nozzle.

v-3.fzA.h ypodermic ampoule syringe construction, comprising an elongated integral one-piece sealed -eenvelope,isaidfenvelope being of two different diameters with an annular shoulder between them, afluid ,outletinozzle having an inlet side and an 'Soutien-side; and a bore through' which fluid is adapted to pass from said inlet side to said outlet 'fside,- a diaphragm with an annular wall upstanding from its perimeter, said nozzle fitting within 4esamimm1arzfwallwith'its .inlet .side againstl said f.diaphragm, vfsaid :nozzle :together 'with said r dia- ..:phragmr'fittingwithinzthe larger. diameter portion of `said-#envelope .with the l diaphragm. resting 4fiagainst said.shoulden andra' clamping sleeve surroundingrisaid envelope and clamping the -fsame .aroun'dtsai'df nozzle. withthe annular wallbetween fithefenvelopexbeinge adapted :to: be rupturedfto .exposethe outlet.sideeofnsaid` nozzle. Y .4.5;Ahypodermic ampoulesyringe construction, :comprising 'anrelongated ntegra1 one-piece sealed `zffenvelope,` ay separate 4fluidwout'let nozzle: having an zinletfzside':andaanoutlet side: and-a bore lthrough which fluid is'- adapte'd :tapass ffrorn-:said` -.-in1et 3; vside to saidoutletisidefsaidinozzle being located within rsaidf envelope :intermediate -its-ends so= as ,--to-.divide itrinto -two compartments, one onithe inlet side'fandth'efother .on' thev Outlet -side of Said l.nozzle, an'd-y a'separate clamping :sleeve surround- .m ing said envelope and clampingthe-.vsame around v usaid nozzle,.ftherenvelope.beingadaptedtol beruptured;l to exposelthe outlet-.side ofsaidfnozzle. 5.-.'Afhypodermic-ampoule-syringe: construction comprising-fan -velongatedz tubular one-piece `en- .;5 -velope closed-at both.endsand madeentirely of easily compressible and rupturable sheet-mate- 'Y rial; a-.-sepa1.ate i luid` outlet -.nozzle-.-memberi having :an inlet sideand lan.l outlet side" and` arranged inside .-saidf.- elongated t tubular 4onepiece envelope 5o` intermediate its'Jends-fzso. as toy divide itv into two compartments, namely,.one:.on the` inlet side and fthe-'other ontheoutlet side yof said iluidoutlet f'tnozzlefmember, the :compartment .on/the inlet side .forming a ycollapsiblecontainer for iiuid to ejected andthe-.compartmentuon theoutlet lside Y forminga .-hermetica1ly sealed rupturable lenclosure for the-outlet side'- of: said nozzle ymember; a bore through saidluidfoutlet-.nozzle memberi throughwhichluid .is adapted to` .pass :from Soesaid .collapsible fluid container tosaidoutlet side of said iiuid outletanozzlemember; and-.means selcuring,saidiiuidoutlet nozzlemem-ber. within said elongated. tubular..,one.piece. envelopetzintermediate its endsg5 6.. A. hypodermic-.ampoule syringeconstruction comprising. anelongated. tubular .one-.piece con- ...tainerclosed at.-.botl'1` ends .andlmade entirely of i easily compressiblef and rupturable sheet matev rial; -aseparateiiuidwoutlet Vr1ozzle.memloerlhaving: arl-inlet .siderand `an outlet side -and arranged inside .fsa-idelongated tubular one-piecel compressvible v:and rupturable `container intermediate `its ends vso fas to divide it 'into va .'col1apsible""fluid roomparim-ent fon the"inlet"side :of said-"separate T5:fluidfrzoutletifnozzle -member' 'and fra hermeticlly 5 y sealed rupturable cover compartment on the outlet side of said separate fluid outlet nozzle mem- 1 pass from said'collapsible uid compartment into ber; a bore through said separate fluid outlet nozv zle member th'rough which fluid isk adapted to pass from said collapsible fluidcompartment into said hermetically sealed rupturable coverv compartment Within said elongated tubular` onepiece compressible and rupturable container; and means securing said separate fluid outlet nozzle member inside said elongated tubular ronepiece compressible and rupturable container intermediate its ends.

'7. A hypodermic ampoule syringe construction comprising an elongated tubular one-piece container closed at both ends and made entirely of easily compressible and rupturable sheet material; a separate fluid outlet nozzley member having an inlet side and an outlet side and arranged inside said elongated tubular one-piece compressible and rupturable container intermediate its ends so as to divide it into a collapsible fluid compartment on the inlet side of said separate fluid outlet nozzle member anda herrnetically` sealed rupturable cover compartment on the outlet side of said separate fluid outlet nozzle member; a. bore through said separate fluid outlet nozzle member through which uid is adapted to 0 Number said hermetically sealed' rupturable cover compartment within said elongated tubular one-piece compressible and rupturable container; and a separate clamping member surrounding said elongated tubular one-piece compressible and rupturable container andclamping the same around said separate fluid outlet nozzle member so as to hold said. separate fluid outlet nozzle member within said elongated tubularone-piece compressble and rupturable container non-slidably in axial direction of said container.


REFERENCES CITED The following references are of record in the ile of this patent:

UNITED STATES PATENTS Name Date Marcy Oct. 16, 1928 Contant Sept. 7, 1937 Henderson Nov. 6, 1945 FOREIGN PATENTS Country Date Switzerland Mar. 1, 1916 Number

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US1687502 *Apr 17, 1924Oct 16, 1928Marcy Ernest HCollapsible ampul syringe
US2092501 *Sep 26, 1936Sep 7, 1937Contant Jr IsaacCapsule filling device
US2388323 *Jan 8, 1943Nov 6, 1945Edward HendersonHypodermic syringe unit
CH71853A * Title not available
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US2551902 *Sep 10, 1948May 8, 1951Arthur SchafferDehorning fluid ejector
US2725055 *Jul 7, 1954Nov 29, 1955Baxter Laboratories IncRecipient needle mounting
US3008570 *Mar 30, 1960Nov 14, 1961Brunswick CorpEjector package
US3056404 *Mar 24, 1959Oct 2, 1962Rota App & Maschb Dr HennigAmpule for injections
US3098481 *Jan 17, 1961Jul 23, 1963Astra Apotekarnes Kem FabSterile fluid dispenser
US6206858Dec 16, 1997Mar 27, 2001Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical CollegeBlunt tip cannula with access pin
US6585697Jan 9, 2001Jul 1, 2003Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical CollegeBlunt tip cannula with access pin
DE1064692B *Nov 4, 1955Sep 3, 1959Hoechst AgKanuelenausruestung fuer Spritzampullen u. dgl.
U.S. Classification604/192, 604/201, 604/204
International ClassificationA61M5/28, A61M5/31, A61M5/32
Cooperative ClassificationA61M2005/3118, A61M5/282, A61M5/3202
European ClassificationA61M5/28E1