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Publication numberUS2471088 A
Publication typeGrant
Publication dateMay 24, 1949
Filing dateOct 1, 1947
Priority dateOct 1, 1947
Publication numberUS 2471088 A, US 2471088A, US-A-2471088, US2471088 A, US2471088A
InventorsErnest Ayre James
Original AssigneeClay Adams Company Inc
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Cervical scraper
US 2471088 A
Abstract  available in
Previous page
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Claims  available in
Description  (OCR text may contain errors)

May 24, 1949. J. E. AYRE I 2,471,088

' CERVICAL SCRAPER Filed Oct. 1, i947 NULL/1 4K006 TYPE 0R ERODED 0F C'ERI/IX (FRI/IX INVENTCJFL JAMES ERNEST AYRE ATTORNEY Patented May 24, 1949 [TED STATES CERVICAL SCRAPER Application October 1, 1947, Serial No. 777,218

1 Claim.

My present invention relates in general to an improved and novel scraper for use in spatula cytology technique, and more specifically to an improved scraper for use in selective cytology employed in the diagnosis of any accessible surface cancer.

The selective cytology technique was developed in a search for a method of studying evidence of cancer growth in the cells which become earliest involved in cervical cancer. The squamous cells encircling the tiny cervical opening at the squamo-columnar junction constitute a key point of origin for cancer more frequently than any other single focus in the female body. The scraper test offers a technique providing surface biopsy information of these cells prior to their actual desquamation. The idea is to detect evidence of the earliest cell change in malignancy and of precancerous cell changes. It must be emphasized that the surgical biopsy is dependent for success upon the lesion being visually demonstrable. Numerous cases have been encountered. where a single biopsy missed the growth while repeat sections revealed a small cancer. By study of cells in selective cytology smears, morphologic changes have been identified believed to constitute a precancer cell-complex. Through early diagnosis of cancer by routine cytology tests, death from cancer of the cervix should become highly preventable.

One of the important objects of my present invention is to provide a novel and improved scraper of particular advantage in the selective method for obtaining surface biopsy from the squamo-columnar junction of the cervix, and of general advantage in the diagnosis of any accessible surface cancer, e. g., tongue, lip, throat, skin and vulva.

Another important object of my invention is to provide a cervical scraper which is generally elongated in configuration and possesses a degree of flexibility, the scraper having one end thereof constructed to take a smear of a nulliparous type of cervix, while the opposite end is constructed to be adapted for a parous or eroded type of cervix.

A more specific object of my invention is to provide a thin elongated scraper, one end thereof having the form of a broad blade of uniform width, while the opposite end generally has a pair of divergent protuberances whereby one of them functions as a pivot for the other as it is rotated during gentle scraping of the entire squamo-columnar junction throughout its circumference.

Still other objects of my invention will appear as this description proceeds, it being emphasized that my present scraper is extremely economical in manufacture thereby to make entirely practical a simple oflice test for uterine cancer diagnosis.

In the drawing:

Fig. l is a full size front view of a scraper constructed in accordance with my invention;

Fig. 2 is a section taken along line 2-2 of Fig. 1 looking in the direction of the arrows;

Fig. 3 is an end view of the spatula viewed from the blade end;

Fig. 4 shows the manner of using the hook end of the scraper; and

Fig. 5 illustrates the use of the broad blade end of the scraper.

Referring now to the accompanying drawing, the scraper is generally of the configuration depicted in Fig. 1. The intermediate section I of the elongated scraper is a narrow thin strip of generally rectangular shape. One end of the strip 1 is formed into a broad blade or paddle 2 whose sides are parallel, and whose leading edge 2-3 is arcuate. The opposite end t of the strip 1 is essentially heart-shaped in that it comprises a pair of divergent protuberances or rounded peaks 5 and 6. The protuberance 6 is larger than its mate, and extends beyond it. The arcuate valley or concavity 1 between the peaks or convex sections 5 and 6 functions as a scraping edge. The concave and convex sections 1 and 6 function as a scraping edge. The entire strip is made of thin wood, but may be pressed from a plastic material, or a pulp material such as cardboard. The scraper may, also be made of metal. The scraper is disposable after use for obtaining a surface biopsy. It will be noted that the edges of the section t are rounded. The width of blade 2 is somewhat less than the width of section 4.

The method of taking a cervical smear for selective cytology requires first the adequate exposure of the cervix with a bivalve speculum. The mucus present at the external as is aspirated using a small glass pipette, or it may be wiped on" with a cotton swab and discarded. In all cases we take both the external os smear by aspiration and the scraper smear for selectivity. In these cases the aspirated mucus is placed on a slide for the usual staining procedure, preceding the taking of the scraper test. Following the removal of excess mucus, the squamo-columnar junction is visualized. The precise method of taking the scraper test will vary according to the type of cervix, e. g., the presence of extensive lacerations or erosions will modify the procedure.

A nulliparous or healthy-appearing cervix showing the squamo-columnar junction just outside the circle of the cervical opening may readily be approached by simply placing the end 4 of the scraper gently against the cervical opening. Reference is made to Fig. 4 which shows the manner of using the section 4 for a nulliparous type of cervix. The, extensive, peak 6 is gently posi-. tioned, as shown, against the cervical opening 8. While held in this position a rotary movement, indicated by the circular arrow, permits light scraping of the entire squamo-columnar junction 9 throughout its circumference. By rotating the scraper the entire circumference of this cancer zone may be surface biopsied. from this key point show the earliest indication of incipient carcinoma before any lesion may be recognized by the naked eye. The hook end 4 is not suitable for cervices with long erosioris,v as the scraping might miss the. squamous tissue, obtainng. a. fsurfa e biopsy of landular tissue only.

Barons. cervices. more commonly exhibit a larger portion oi th dd sh landular cerv a p thelium. with or without an erosion, eversion or laceration. For cervices of this type the scraper test is taken by scraping along. the squamo-columilar marg n at the most suspicious area with the other end 2 of the scraper. This. is shown ii -Fig. which depicts the. manner of using the end 2. The. scraper is rotated in the direction of the. arrow. Whether the secretion is derived as shown in Fig, 4 or Fig. 5 it is spread over a glass slide. and th n process d to. pre erve. in a glyoe media for 7-14 days so as to submit to. any special-.

The c lls. shed ized cytological laboratory for experienced interpretation.

In summary, from a cytological study of over 3000 cases, by the use of cervical cytology tests in general and the scraper technique in particular, death from carcinoma of the cervix could potentially become highly preventable. It would appear that lay routine cervical; cytology tests With a scraper of the present type it, becomes more practical and easier to take advantage of the life-saving possibilities offered by cytology.

What I claim is:

A cervical scraper consisting of an elongated strip, one; end of the. strip being generally triangular and having a pair of unsymmetrical convex end sectionsoonnected by a section of concave configuration, one of said convex sections being substantially longer than the other, and said longersection being adapted to enter the cervical opening and function as a pivot, the shorter section functioningas. a, rotatable wing relative to said. pivot, said concave section being adapted to scrape cells from the. squamowolumnarjunction inresponse to. rotation of the scraper about the Pivo aflorde y said. longer section.


REEERENQES C TED The fol-lowing references are of: record in the file of this patent;

Catalog of George Pilling- 8: Son Co. of Philadelphia, published in 1921, page 122-. (Copy in Division 55.)-

Non-Patent Citations
1 *None
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US2514665 *Jan 11, 1949Jul 11, 1950Ernest MyllerMedical instrument
US2839051 *Feb 24, 1956Jun 17, 1958Chester Martin HCervicotome
US3315661 *Sep 24, 1964Apr 25, 1967Groat Richard ACervical scrapers
US3327702 *Mar 24, 1966Jun 27, 1967De Marco John JBiopsy knife for cutting a conical specimen
US3352299 *Nov 25, 1964Nov 14, 1967Dept Of Cytopathology And CellCyologic pan-scraper
US3485236 *Dec 9, 1965Dec 23, 1969Becton Dickinson CoBiopsy specimen collecting and spreading device
US3554185 *Feb 29, 1968Jan 12, 1971Kohl Gerald CCervical biopsy-sampling instrument
US3592186 *Jan 28, 1969Jul 13, 1971Oster ClaudeCytologic scraper
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EP0050632A4 *Apr 13, 1981Sep 12, 1983Accupap IncPap smear t-zone sampler.
WO1981002974A1 *Apr 13, 1981Oct 29, 1981R HasselbrackPap smear t-zone sampler
WO1999025251A1 *Nov 13, 1998May 27, 1999Harwill Industries (Pty.) Ltd.Medical spatula
WO2002053698A1 *Dec 26, 2001Jul 11, 2002Cole Robert BSpatula for biological sampling
WO2002080776A1Apr 4, 2002Oct 17, 2002Ashwood Timber & Plastics LtdDevice for taking samples of ceels from the cervix uteri
U.S. Classification600/570, D24/149
International ClassificationA61B10/00, A61B10/02
Cooperative ClassificationA61B10/0291
European ClassificationA61B10/02U