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Publication numberUS2812117 A
Publication typeGrant
Publication dateNov 5, 1957
Filing dateMar 29, 1955
Priority dateMar 29, 1955
Publication numberUS 2812117 A, US 2812117A, US-A-2812117, US2812117 A, US2812117A
InventorsAlex M Butkus, George R Ryan
Original AssigneeAbbott Lab
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Venoclysis apparatus
US 2812117 A
Abstract  available in
Previous page
Next page
Claims  available in
Description  (OCR text may contain errors)


. jrzurzfors 4/exMBazkas A Gee e]? Egan flier/264p Filed March 29, 1955 VENOCLYSIS APPARATUS Alex M. Butkus and George R. Ryan, Waukegan, 111., V

assignors to Abbott Laboratories, North Chicago, III., 'a corporation of Illinois The present invention relates to an improved apparatus for the administration of parenteral liquids and more particularly to an improved closure means for a container ofliquids which are administered by means of a hypodermic syringe.

In accordance with modern hospital procedure it has become common practice to prepare stock solutions of medicinals which can be used for a large number of patients. The containers of stock solution of the above type are normally provided with a penetrable resealable closure or rubber stopper through which a hypodermic needle is inserted when it is desired to withdraw an aliquot of the solution into a hypodermic syringe. However, because of the dangers of contamination of the solution and the introduction of particles which might cause embolyson as a result of the coring of the stopper by repeated insertion of a hypodermic needle through the stopper, in addition to the possibility of inadequate resealing of the stopper after withdrawing the hypodermic needle, the use of a penetrable closure on a container for a stock solution of a medicinial has many objectionable features which should be corrected.

It is therefore an object of the present invention to provide an improved closure means for a medicinal container which substantially reduces contamination of the medicinal contents of the container.

Another object of the invention is to provide a simple, safe, and economical means of access to the interior of the said container.

Other objects of the present invention will be apparent from the detailed description and claims to follow.

In the drawing Figure 1 is a side elevation view of the closure cap means operatively mounted on a medicinal container showing the manner in which a hypodermic syringe coacts therewith.

Figure 2 is a planned view of the closure means shown in Figure 1.

Figure 3 is a vertical sectional view of the closure cap shown in Figure 1 with sealing caps mounted thereon.

The improved apparatus of the present invention as illustrated in the drawing is shown operatively associated with a container for intravenous liquids as' represented by a container or glass bottle 1 in an inverted position with the neck 2 thereof projecting downwardly. The neck 2 of the said container is provided with suitable external screw threads. The closure cap means 3 which is preferably formed of a stable plastic material, such as polyethylene plastic, is provided with a preferably cylindrical body section 4 having internal screw threads 5, said threads 5 being operatively engageable with the external threads on the neck 2 of the bottle 1.

The end wall 6 of the cap 3 is provided with a discharge passage 7 extending therethrough. The wall section 8 of the upper end of the said passage 7 extending inwardly above the inner surface of wall 6 so that the upper end of passage 7 is elevated above the end wall 6, thereby providing an area in which sedimentation may collect and 2,812,117 Patented Nov. 5, 1957 thereby reduce the danger of clogging the said passage 7. The enlarged wall section 8 of passage 7 also provides a seat for a filter element (not shown) which extends upwardly into the interior of the container 1 and which can be used when considered necessary.

The inner wall surface of the outwardly extending wall section 9 defining the passage 7 provides thereof an inwardly tapering surface 10 which is suitable for receiving a male Luer taper element, as provided on the hub of a standard hypodermic syringe.

Spaced laterally from passage 7 on the wall 6 of the cap member 3 is a tubular vent section 11 extending outwardly from the lower surface of the end wall 6. Intermediate the ends thereof the tubular section 11 is provided with an inwardly tapering restricted wall section 12 which forms the seat of a ball check valve member 13. Spaced upwardly from said tapered section 12 is a chamber 14 of slightly greater diameter than said taper section 12 into which is inserted the ball check valve member 13 which completes the ball check valve assembly. The ball valve member 13 is retained in the chamber 14 by means of the inwardly extending lugs 15 at the upper end of the chamber 14. The lower end of tubular section 11 is provided on the inner surface thereof with inwardly tapering wall portions 16 which are suitable for receiving a male Luer taper element. Mounted on the outer surface of the lower end of the tubular section 11 is a cap 17 which has a passage 18 extending therethrough'at the outer end thereof through which air passes and which also has a chamber 19 spaced inwardlyfrom the outer end which receives a small wad of cotton or other filtering material so that air passing therethrough is rendered sterile and free of dust. The inner surface of end wall 6 is also preferably provided with a raised sealing ring 20.

In packaging and handling of the said closure cap 3 prior to mounting on a container, it is preferred to provide the body section 4 with a sealing cover 21 which completely encloses the upper end of the body section and prevents dust and bacteria entering the cap member. Also, as an essential element of the present invention, the lower end of the passage 7 is provided with a sealing means 22 secured in sealing engagement with the wall section 9, except when a hypodermic syringe is being used to withdraw medicament from the container 1, which effectively prevents the entry of bacteria or dust and maintains the closure cap 3 in a sterile condition.

In operation, a hypodermic syringe 23 (without needle) having a hub with a Luer taper at the outer end thereof is inserted into the tapered surface 10 of the discharge passage 7 of the closure cap 3 mounted on a medicinal container 1 while the said container is in its normal vertical position.

After the hypodermic syringe hub forms a sealing engagement with the tapered surface 10, the assembly is thereupon inverted to the position shown in Figure 1 of the drawing. The hypodermic syringe plunger is then moved outwardly, drawing liquid medicinal from the container 1 into the hypodermic syringe. When the desired volume of medicinal has been withdrawn, the medicinal container 1 is then moved into its normal vertical position and the hypodermic syringe removed from the closure cap 3. Thereafter, the sealing cover 21 and sealing means 22 are replaced on the cap 3 so that the medicinal content of the container is maintained in a sterile condition. The medicinal can then be injected in the usual manner by providing the hypodermic syringe with a suitable hypodermic needle for injection.

While the closure member is preferably made of a plastic material such as polyethylene, it should be understood that other plastics and other materials can be used, among those which are suitable for the present invention are nylon, polystyrene and polyvinyl plastics, stainless steel, aluminum, rubber and glass. Also, while the specific form of the cap shown in the drawing has the end wall 6, the discharge passage 7, and the tubular vent section 11 integral with the body section 4 of the cap, it should be understood that, if desired, these elements can be formed as a separate insert member which can be detachably mounted in a circular opening in the cap in the manner commonly employed in the art. It should also be understood that the Luer taper surface, such as wall portion 16, can be provided on the exterior of the section so as to fit into a female Luer taper element without departing from the present invention.

Others may readily adapt the invention for use under various conditions of service, by employing one or more of the modifications described, or the equivalent thereof. As at present advised with respect to the scope of our invention, we desire to claim the following subject matter.

1. A fluid dispensing container closure comprising a body section with end wall and upstanding lateral surface provided with means adapted to form a fluid-tight detachable connection with the outlet of a fluid container, a cover member detachably secured to said upstanding lateral surface until such time as the closure is attached to a container outlet and which protects the interior of said body section against contamination, said end Wall having a tubular sectionextending outwardly therefrom with an air filter and valve means associated therewith, a tubular liquid discharge member spaced laterally from the said tubular section which extends outwardly from said end wall, said tubular member having at the outer end thereof an enlarged inner chamber with tapered lateral surfaces adapted to receive in sealing engagement a hypodermic syringe hub, and a sealing cap member mounted on the said tubular member in the absence of a hypodermic syringe hub being in engagement therewith.

2. A fluid dispensing container closure comprising a plastic body section with integral end wall and upstanding lateral surface provided with means of forming a fluidtight detachable connection with the outlet of a fluid container, said lateral surface adapted to removably support a cover member which is detachably secured thereto until such time as the closure is attached to a container outlet and which protects the interior of said body section against contamination, said end wall having a tubular section extending outwardly therefrom which has associated therewith an air valve means, a tubular liquid discharge member integral with said wall extending outwardly therefrom and spaced laterally from said tubular section, said tubular member having the inner end thereof extending inwardly above the plane of said end wall and having at the outer end thereof an enlarged inner chamber with a tapered lateral surface adapted to receive in sealing engagement therewith a hypodermic syringe hub, and a sealing cap member mounted on the said tubular member in the absence of a hypodermic syringe hub being in engagement therewith.

References Cited in the file of this patent UNITED STATES PATENTS 537,111 Henderson Apr. 9, 1895 881,241 Hubbard Mar. 10, 1908 900,103 Kessler Oct. 6, 1908 2,210,676 Krannak Aug. 6, 1940 2,462,575 Walker Feb. 22, 1949 2,636,502 Buechel Apr. 28, 1953 2,736,469 Stone Feb. 28, 1956

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US537111 *Jan 10, 1895Apr 9, 1895 Oiler-tip for bottles or cans
US881241 *Apr 3, 1906Mar 10, 1908Hendley W HubbardOil-can.
US900103 *Sep 22, 1906Oct 6, 1908Charles E HoltzmanPortable receptacle for liquids.
US2210676 *May 25, 1939Aug 6, 1940Min A Max CompanyPouring attachment for cans
US2462575 *Dec 27, 1944Feb 22, 1949Uel T WalkerPipe coupling
US2636502 *Sep 12, 1949Apr 28, 1953Selma Buechel PaulineApparatus for cleaning hypodermic needles
US2736469 *Apr 15, 1952Feb 28, 1956Stone Ashton KSealing and pouring closures
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US2990979 *Jan 27, 1959Jul 4, 1961Signal Mfg CoAttachment for floor treating apparatus
US3102561 *Jun 19, 1961Sep 3, 1963Black Products CoSelf venting spout
US3128917 *Apr 14, 1964 krause
US3146917 *Feb 16, 1961Sep 1, 1964Lever Brothers LtdMethod of and apparatus for dispensing liquids
US3149758 *Nov 1, 1961Sep 22, 1964Millipore Filter CorpCombination filter and flow divider for gas and liquid
US3467270 *Aug 3, 1967Sep 16, 1969Hall Robert MCap
US3622049 *May 5, 1969Nov 23, 1971Schering CorpDispensing system
US3805986 *Feb 17, 1971Apr 23, 1974LabazContainers
US3904060 *Feb 26, 1974Sep 9, 1975American Hospital Supply CorpThree barrier closure system for medical liquid container
US4235344 *Jan 29, 1979Nov 25, 1980Baxter Travenol Laboratories, Inc.Irrigation cap
US4336800 *Aug 1, 1980Jun 29, 1982Oximetrix, Inc.Intravenous metering device
US4567926 *Jan 9, 1984Feb 4, 1986Carb-A-Drink International, Inc.Apparatus for and method of dispensing bulk liquids
US4590974 *Dec 22, 1983May 27, 1986Carb-A-Drink International, Inc.Beverage dispenser
US4722733 *Feb 26, 1986Feb 2, 1988Intelligent Medicine, Inc.Drug handling apparatus and method
US4928853 *Aug 19, 1988May 29, 1990Fountain Fresh, Inc.End aisle fluid mixing and dispensing system
US4951845 *Jan 17, 1989Aug 28, 1990Abbott LaboratoriesClosure with filter
US4967922 *May 3, 1989Nov 6, 1990Imperial Chemical Industries PlcContainers and caps therefor
US4997429 *Dec 28, 1988Mar 5, 1991Sherwood Medical CompanyEnteral bottle cap with vent valve
US5041105 *Oct 29, 1990Aug 20, 1991Sherwood Medical CompanyVented spike connection component
US5074440 *Jul 16, 1990Dec 24, 1991Alcon Laboratories, Inc.Container for dispensing preservative-free preparations
US5174476 *May 6, 1991Dec 29, 1992Steiner Company, Inc.Liquid soap dispensing system
US5209377 *Aug 6, 1992May 11, 1993Steiner Robert LDisposable refill cartridge for a liquid soap dispensing system
US5462209 *Jul 12, 1994Oct 31, 1995Contico International, Inc.Trigger sprayer operable in upright, downturned and inverted positions
US5467901 *Oct 21, 1994Nov 21, 1995Contico International, Inc.Trigger sprayer operable in upright, downturned & inverted positions
US5540360 *May 13, 1994Jul 30, 1996Contico International, Inc.Invertible trigger sprayer assembly
US5664702 *Jun 27, 1996Sep 9, 1997Beauchamp; Christopher E.Foot operated beer keg pressurizer
US5782383 *Sep 4, 1996Jul 21, 1998Rexan Closures Inc.Dispensing closure for sealed enteral fluid containers
US9237986 *Mar 14, 2013Jan 19, 2016Carefusion 303, Inc.Vial access cap and syringe with gravity-assisted valve
US9750662Dec 18, 2015Sep 5, 2017Carefusion 303, Inc.Syringe with gravity-assisted valve
US20050127107 *Sep 17, 2002Jun 16, 2005Pierre MbonyumuhireDosing device with a medium reservoir and a pump device
US20140261876 *Mar 14, 2013Sep 18, 2014George Michel MansourVial access cap and syringe with gravity-assisted valve
US20150047741 *Aug 19, 2013Feb 19, 2015Max Time GmbHRefill system of a liquid container
DE4428484A1 *Aug 11, 1994Feb 16, 1995Fresenius AgDevice for the accommodation of nutrient substrate bottles and associated pump
WO1995031399A1 *Mar 21, 1995Nov 23, 1995Contico International, Inc.Invertible trigger sprayer assembly
WO2007036615A2 *Aug 3, 2006Apr 5, 2007Raymond CastanetMethod and device for preserving and dispensing a product in a closed container
WO2007036615A3 *Aug 3, 2006Jul 26, 2007Raymond CastanetMethod and device for preserving and dispensing a product in a closed container
U.S. Classification222/189.9, 222/481, 604/405, 141/301, 215/DIG.300, 141/311.00R
International ClassificationA61J1/00, A61J1/14
Cooperative ClassificationA61J1/1412, A61J2001/1418, Y10S215/03, A61J2001/1487, A61J1/1475, A61J2001/1468, A61J2001/145
European ClassificationA61J1/14P, A61J1/14C