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Publication numberUS2842127 A
Publication typeGrant
Publication dateJul 8, 1958
Filing dateApr 11, 1955
Priority dateApr 15, 1954
Publication numberUS 2842127 A, US 2842127A, US-A-2842127, US2842127 A, US2842127A
InventorsEverett Samuel James
Original AssigneeS & R J Everett & Company Ltd
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Hypodermic syringes
US 2842127 A
Abstract  available in
Previous page
Next page
Claims  available in
Description  (OCR text may contain errors)


HYPODERMIC SYRINGES Samuel James Everett, Thornton Heath, England, assignor to S. & R. J. Everett & Company Limited, Thornton Heath, England, a British company Application April 11, 1955, Serial No. 500,520 Claims priority, application Great Britain April 15, 1954 10 Claims. (Cl. 128-218) One of the difliculties in manufacturing hypodermic syringes and similar apparatus is in providing joints between the various parts of the apparatus which are leakproofand yet can be easily dismantled and which do not present difliculties in sterilisation. in certain circumstances a'lso joints require a certain amount of lubrication and also must not deteriorate with changes in temperature;

The present invention provides a simple and improved form of joint which can be easily dismantled, which is self-lubricating, which gives very satisfactory sealing, and which withstands sterilisation without deterioration while enabling a hypodermic syringe to be made with all these advantages by a very simple and economical construc- According to the invention, a sealing surface is formed by a sealing layer of halogenated ethylene such as polytetrafluoroethylene known as Fluon or polymonochlortrifluorethylene known as Hostaflon on a rigid supporting member preferably formed of material which has a sim ilar coefiicient of expansion as the material of the member with which the sealing surfaces engages. Thus in a syringe having a glass barrel, the piston and front cap may be of a nickel alloy known as Nilo 36 which contains 36% nickel and 64% iron and which has a similar coeflicient of expansion to that of glass and which is coated with Fluon or Hostaflon. Generally Fluon is preferable to Hostaflon.

Various examples of sealing joints according to the invention are shown in the accompanying drawings in which:

Figure 1 shows in longitudinal part section a hypodermic syringe having a piston and front cap according to the invention;

Figure 2 shows a form of piston particularly for a disposable ampoule;

Figure 3 shows another form of piston for a disposable ampoule;

Figure 4 shows a plunger for a hypodermic syringe;

Figure 5 shows a stop-cock for a hypodermic syringe according to the invention; and

Figure 6 shows another form of hypodermic syringe.

In Figure 1, the syringe comprises a glass barrel 1 open at both ends, and a front cap consisting of a disc 2 of Nilo 36 flanged at 3 and having a tapered central spigot 4 riveted into the disc 2 to form a flange 5. A fluid-tight seal between the barrel 1 and disc 2 is formed by a hat shaped Fluon washer 6 which is applied to the disc 3 and held by the flange 5. The barrel 1 and disc 2 are held together in a tubular syringe body 8, cut away at 9 to enable the piston and the scale on the barrel to be observed, and having an inwardly projecting flange 7 at the front end. A rear cap 10 is screwed on to threads 11 on the rear end of the body 8 so as to engage the rear end of the barrel 1 pressing the front end of the barrel firmly on to the Fluon washer 6 on the disc 2 which is seated against the flange 7.

The piston comprises a Nilo disc 12 coated on its front rates PatentD 2,842,127 Patented July 8 1958 face and periphery with Fluon 13 making linear contact of about A: of an inch with the bore of the barrel 1. The Fluon coating is .010 of an inch thick. The disc is secured to a piston rod 14 which carries a guide disc 15 preferably of Nilo a distance of between one and two diameters of the disc behind the disc. The rear end of the piston rod 14 has a finger piece 16. Linear contact of about A; of an inch gives a satisfactory permanent seal in bores of up to 1% inches diameter.

In Figure 2, a piston for a disposable ampoule of .010 of an inch thick phial is shown, which consists of a Nilo disc 20 and Fluon cup washer 21. The disc 20 maintains the shape and size of the Fluon washer 21 during and after sterilisation. The disc 20 and washer 21 are carried by a nylon piston 22 which passes through the central hole of the disc 20 and washer 21 and also has a threaded projection 23 from the rear face which can be engaged by a plunger. In a disposable ampoule, a linear contact of about .010 of an inch is satisfactory.

In Figure 3, the piston comprises a cup 26 of thin Nilo coated on its outer surfaces by spraying with Fluon 27 and having a pair of inwardly projecting dimples 28 which can be engaged by a bayonet attachment on a plunger. The Fluon coated cup 26 may be formed by drawing a flat disc of coated Nilo.

Figure 4 shows a similar construction of sealing washer to Figure 2 consisting of a Nilo disc 30 and Fluon cup washer 31 mounted in a nylon plunger 32 of a hypodermic syringe.

Figure 5 shows a stop-cock according to the invention, formed in the nozzle of a syringe, The nozzle 35, tapered to take a hypodermic needle, has a central bore 36 and a large central boss 37 through which is a transverse bore 38 of accurate cylindrical form and of a diameter substantially greater than the bore 36. The valve member consists of a plug 39 of a material of a similar coefficient of expansion to that of the body 37 and having a diameter slightly less than the diameter of the transverse hole 38 by an amount of, say, 0.016 of an inch.

The plug is surrounded by a tube 40 of Fluon which fits precisely in the bore 38. Slightly to one side of the centre of the plug, a groove 41 is turned in the outer surface of the Fluon tube so that the tube is reduced in thickness to a few thousandths of an inch. The parallel portion of the tube of full diameter, completely prevents the passage of fluid through the bore 36, but when the plug is pressed sideways so that the groove 41 registers with the bore 36, the fluid can flow. The groove in the tube may have varying shapes so as to give a gradual or abrupt cut-oil. In an alternative form the groove may be formed in the plug itself into which the Fluon is moulded.

'Figure 6 shows a syringe in which the front cap comprises a central nozzle 44 riveted into two Nilo discs 45, 46 forming a spigot of a diameter less than the bore of the barrel 47 by .016 of an inch, and a further stiffening disc 48 which forms a flange between the disc 46 and a thin metal disc 49 of larger diameter than the disc 48. The discs 45, 46 are surrounded by a hat-shaped Fluon disc washer 50 about .010 of an inch thick. The parts are heated to 230 C. and assembled, so that the Fluon washer is squeezed tightly between the barrel and cap. The front cap is then held in place by spinning the flange of the disc 49 over a ridge or heading 51 surrounding the end of the barrel 47. The seal is formed at 52, and it may be desirable in some cases to cut away the front of the disc.

Apart from Nilo, other rigid materials which are particularly suitable as backings or supports for use in conjunction with the Fluon or Hostaflon which forms the self-lubricating sealing member are glass, stainless steel,

and stainless iron. Preferably any such combination of sealing member and backing should withstand sterilising at 160 degrees centigrade.

The Nile alloy referred to is particularly suitable for use in conjunction with a Fluon sealing surface fitting against glass having a low coeificient of expansion or ltnown by the registered trademark Pyrex. Stainless iron is particularly suitable for use with glass having a coefficient of expansion of about 10.5 10

I claim:

1. A hypodermic syringe comprising a barrel, an end cap formed of a material having a coefficient of expansion substantially equal to that of said barrel, said end cap comprising a first portion slightly less in diameter than the internal diameter of said barrel and extending into said barrel, a nozzle secured to said end cap, a sealing member formed by a relatively thin layer of a halogenated ethylene of the class consisting of polytetrafiuorethylene and polymonochlortrifluorethylene interposed between the, adjacent surfaces of said barrel and said end cap, and means for securing said end cap to said barrel.

2. A hypodermic syringe according to claim 1, in which said end cap comprises a second portion having a diameter greater than the internal diameter of said barrel and extending over the end of said barrel between said sealing member and said securing means.

3. A hypodermic syringe according to claim 2, in which said second portion is a flange formed on said portion inserted into the barrel.

4. A hypodermic syringe according to claim 2 in which said second portion is a separate disc.

5. A hypodermic syringe according to claim 2 in which said securing means comprises an outwardly extending bead on said barrel and a third portion in contact with said second portion and having its periphery spun over said head. i

6. A hypodermic syring according to claim 1 in which said holding means comprises a tubular syringe body encompassing said barrel, an inwardly extending flange por- 4 tion at one end of said body in contact with said second portion, and a threaded cap engaging threads on the other end of said body screwed to bear upon the rear end of said barrel and thus to press the front end of said barrel firmly onto said sealing layer.

7. A hypodermic syringe according to claim 1 in which said sealing member is hat-shaped and wherein the crown extends over the inside face of said first portion of said end cap.

8. A hypodermic syringe according to claim 1 wherein said end cap material is a nickel alloy comprising nickel and iron.

9. A hypodermic syringe according to claim 1 wherein said sealing member is secured to said end cap by a rivet.

10. A hypodermic syringe comprising a barrel, an end cap and nozzle combination over one end of said barrel, a piston member slidable within said barrel and of a diameter slightly less than the internal diameter of the barrel, said piston comprising an annular groove, a thin supporting metal washer of a diameter slightly less than the internal diameter of the barrel, located within said groove, and formed of a material having a coefiicient of expansion substantially equal to that of said barrel and a sealing layer of a halogenated ethylene of the class consisting of polytetrafluorethylene and polymonochlortrifluorethylene adjacent to said washer in said groove and extending over the periphery of said washer.

References Cited in the file of this patent UNITED STATES PATENTS 2,648,334 Brown et al. Aug. 11, .1953 2,656,836 Hickey Oct. 27, 1953 2,735,735 Abel Feb. 21, 1956 FOREIGN PATENTS 590,503 Great Britain July 21, 1947 OTHER REFERENCES Modern Plastics, December 1952; article on Fluorocarbons, pages 79-87 and 170-178.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2648334 *Oct 28, 1949Aug 11, 1953TurnbullHypodermic injection assembly
US2656836 *Sep 26, 1950Oct 27, 1953Bishop & Co Platinum Works JHypodermic syringe
US2735735 *Apr 14, 1952Feb 21, 1956 Syringe construction
GB590503A * Title not available
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3380451 *Jun 14, 1965Apr 30, 1968Cloyd J. Sorensen Jr.Two compartment syringe
US3828987 *Jun 2, 1972Aug 13, 1974Drummond Instr CoDispensing micropipette apparatus having disposable parts for delivering a preselected quantity of fluid
US3958570 *Sep 3, 1974May 25, 1976Vogelman Joseph HSyringes and syringe capsules
US4015602 *Dec 8, 1975Apr 5, 1977Mid-States Laboratories, Inc.Ear mold injection dispenser
US4030498 *Jul 22, 1976Jun 21, 1977Baxter Travenol Laboratories, Inc.Syringe
US4397903 *May 1, 1981Aug 9, 1983The West CompanyMolded articles
US4664655 *Mar 20, 1986May 12, 1987Norman OrentreichHigh viscosity fluid delivery system
US4758234 *Mar 17, 1987Jul 19, 1988Norman OrentreichHigh viscosity fluid delivery system
US7547297Nov 12, 2003Jun 16, 2009West Pharmaceutical Services Deutschland Gmbh & Co. KgPharmaceutical syringe piston
US7691308Jan 5, 2007Apr 6, 2010West Pharmceutical Services Deutschland GmbH & Co. KGMethod and device for producing a pharmaceutical syringe piston stopper
US20040099994 *Nov 12, 2003May 27, 2004West Pharmaceutical Services Deutschland Gmbh & Co. KgPharmaceutical syringe piston and method and device therefor
US20070107204 *Jan 5, 2007May 17, 2007West Pharmaceutical Services Deutchland GmbH & Co KGMethod and Device for Producing A Pharmaceutical Syringe Piston Stopper
WO1996000098A1 *Jun 23, 1995Jan 4, 1996Schering AktiengesellschaftMulti-component syringe with a glass barrel
WO2009030974A1 *Sep 3, 2007Mar 12, 2009Becton Dickinson FranceMedical device and lubricant coating therefor
U.S. Classification604/240
International ClassificationA61M5/315, A61M5/31, A61M5/24
Cooperative ClassificationA61M2005/2407, A61M2005/3128, A61M5/31513, A61M5/31, A61M5/24
European ClassificationA61M5/31, A61M5/315C1, A61M5/24