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Publication numberUS2884150 A
Publication typeGrant
Publication dateApr 28, 1959
Filing dateApr 5, 1956
Priority dateApr 5, 1956
Publication numberUS 2884150 A, US 2884150A, US-A-2884150, US2884150 A, US2884150A
InventorsTheodore E Weichselbaum, Edwin G Weischselbaum
Original AssigneeBiolog Res Inc
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Hematocrit closures
US 2884150 A
Abstract  available in
Previous page
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Claims  available in
Description  (OCR text may contain errors)

1'. EL WEIEHSELBAUM ETAL April 2 s, 1959 HEMATOCRIT CLOSURES Filed April 5, 1956 2 Sheets-Shegt 1 FIG. 3v


FIG. 4


T. E WEICHSELBAUM EI'AL April 28, 1959 HEMATOCRIT CLOSURES 2 Sheets-Sheet 2 Filed April 5, 1956 FIG. 8

FIG. 9

INVENTOR. WEICHSELBAUM THEODORE EDWIN WEICHSELBAUM United States Patent O HEMATOCRIT CLOSURES Theodore E. Weichselbaum and Edwin G. Weichselbaum, Normandy, Mo. assignors to Biological Research, Inc. Normandy, Mo., a corporation of Missouri Application April 5, 1956, Serial N0. 576,400

1 Claim. (Cl. 215-41) This invention relates in general to certain new and useful improvements in a medical laboratory device and, morc particularly, to a closure element for hematocrit tubes.

For purpose of certain type of medical diagnosis, a sample of the patients blood is placed in an elongated glass capillary tube which is usually referred to as an hematocrit tube. This hematocrit tube is of extremely small internal and external diametral size. Consequently, the blood sample is ordinarily sucked up through one open end of the tube either by capillarity or by applying suction to the other open end of the tube. When appropriately filled with the requisite amount of blood, the hematocrit tube is sealed by placing one end in a bot flame and fusing the glass of the tube. The sealed tube is then placed in a centrifuge and whirled to produce a centrifugal separation between the red corpuscles and the Plasma in the sample. The analysis is compieted by measuring the length of the columns thus formed in the hematocrit tube and computing the arithmetical proportion between such lengths. It has long been recognized that this analytical procedure is not as accurate as it should be because it is very difficult to fuse the end of a hernatocrit tube With any satisfactory degree of reproducibility. Very often the globule of glass formed during the fusing procedure is of irregular shape and, as a result, it is very difficult to make a visual measurement, since it is very diflficult to locate the exact bottom margin of the column by visual observation. In addition to this, the globule of glass may be large or small and Will accordingly produce various difficult mem'scus eflects which also introduce difficulty in visually reading the hematocrit determination. The fusing cf the glass may also overheat the blood sample causing decomposition Within sample and thereby producing erratic results.

Finally the hematocrit tube must ordinarily be filled by the technician er intern at the time the sample is taken from the patient and then carried to the laboratory :for sealing and centrifuging. Consequently, the bematocrit tube is open at both ends for an appreciable period of time so that a portion of the sample can, and frequently does, leak out. These circumstances frequently produce additional inaccuracy and error in the analytical results.

It is, therefore, the object of the present invention to provide a closure for hematocrit tubes and the like which is simple, effective, and easy to apply.

It is another object of the present invention to provide a closure for hematocrit tubes and the like which is inexpensive and, therefore, disposable.

lt is also an object of the present invention to prov-ide a closure for hematocrit tubes and the like which can be manufactured in a uniformed size so as to provide a substantially accurate point of reference from which analytical measurements can be accurately made.

With the above and other objects in view, our invention resides in the novel features cf form, construcice tion, arrangement, and combination of parts presently described and pointed out in the claims.

In the accompanying drawings (two sheets) Fig. 1 is a perspective view of a cluster of hematocrit tube closures constructed in accordance with and embodying the present invention;

Fig. 2 is a transverse sectional view taken along line 2-2 of Fig. 1;

Fig. 3 is an end elevational view of the cluster of hematocrit tube closures showing an hematocrit tube in place in one such closure;

Fig. 4 is an end elevational view similar to Fig. 3, diagrammatically illustrating the manner in which an hematocrit tube and its individual closure element is severed from the cluster;

Fig. 5 is an elevational view of an hematocrit tube and its individual closure element severed from the cluster, partly broken away and in section;

Fig. 6 is a perspective view of a modified form of closure-cluster constructed in accordance with the present invention;

Fig. 7 is a sectional view taken along 1ine 7-7 cf Fig. 6;

Fig. 8 is a perspective view of another modified fonn of closure-cluster constructed in accordance with and embodying the present invention; and

Fig. 9 is a sectional view taken along line 99 of Fig. 8.

Referring now in more detail and by reference characters to the drawings, which illustrate a preferred embodirnent of the present invention, A designates a closurecluster molded or otherwise suitably formed from a plastomer such as vinyl polymers, natural rubber or other soft rubber-like material comprising a central runner cf more or less rod-like shape and having a plurality of uniformly spaced laterally projecting gates 2 which are narrowed down at their outer ends to relatively thin forklike necks 3 which integrally connect to small th-imbleshaped closure elements 4 each having substantially cylindrical side Walls 5 and a bottom Wall 6 defining a tubular recess 7 having a circular top opening 8. Formed integrally With and projecting upwardly from the bottom Wall 6 is a concentrically positioned elongated, somewhat tapered, plug member 9 which terminates at its upper end in a round-pointed tip lt), the latter being spaced downwardly a short distance below the rim of the opening 8.

Although in Fig. 1, the hematocrit tube closure-cluster A is shown With ten symmetrically arranged closure elements 4, the present invention is by no means limited to this specific arrangement. If desired, any number of such closure elements 4 can be arranged in a cluster and the arrangernent need not be symmetrical. Because hematocrit tubes are very small and the closure elements 4 are of correspondingly small size it is desirahle t0 anange a plurality of such closure elements 4 in a cluster for ease in handling. The outer cylindrical wall 5 ot" the cup-like element serves to guide the hematocrit tube smoothly and accurately onto the plug member 10. Because of the very small size of the hematocrit tube it thus becomes possible to efiect a secure and accurate closure.

In use, the intern o-r technician will fi1l the hematocrit tube H With the desired amount of blood san1ple and im mediately insert the lower end thereof in one of the closure elements 4 of the hematocrit tube closure-clustcr A substantially in the manner shown in Fig. 3. The hematocrit tube H is inserted only part way into the closure element 4 to the degree which may be comveniently obtained by a light downward pushing action With the fingers. T hereupon the closure element 4, into which the hematocrit tube H has been inserted, is torn oif somewhat in the manner shown in Fig. 4. Finally the hematocrit tube H and closure element 4 are tapped lightly against the table 01' other similar flat surface With a gent1e tapping action and the tapered plug member is driven snug1y up into the bore cf the hematocrit tube H substantially as shown in Fig. 5.

The closed hematocrit tube H can then be placed in a centrifuge and whirled in the conventional manner to effect a separation between the red corpuscles and the plasma. When the separation has been completed, the hematocrit tube H is removed from the centrifuge and measured in the usual manner. Since the c1osure element 4 is an accurately molded part, the distance between the downwardly presented end face of the bottom Wall 6 and the top surface of the round-pointed tip 10 will always be substantially the same, within very close 1irnits of tolerance. Consequently, the columnar measurements of the hematocrit can always be made accurately and precisely.

If desired, it is possible to provide a closure-cluster B as shown in Fig. 6 and formed of the same type cf materials as the previously described closure-cluster A. The closure-c1uster B, however, comprises a plurality of closure-elements 11 each integrally including a cylindrical wa1l 12 and a bottom wall 13 defining a tubular recess 14 having an interior wa1l face 15 which is of somewhat hour-glass shape as shown in Fig. 7. Molded concentrically With and projecting upwardly from the bottom Wall 13 is a rather broad-based conical plug-member 16. It will be noted that the interior Wall face 15 does not quite touch the plug-member 16 but guides the hematocrit tube securely thereon.

It is also possible to provide a further modified form of closure-cluster C as shown in Fig. 8 and formed cf the same type of material as the previously described closure-cluster A. The closure-cluster C, however, comprises a plurality of closure elements 17 each integrally including a cylindrical bottom member 18 having a flat annular face 19 and a concentric upwardly projecting tapered plug-element 20. At its upper end the plugmernber 20 is integrally provided with a short rod-like guide means 21 which is rounded ofi at its extremity and is of uniform circu1ar cross-sectional shape and is smaller in diametral size than the bore of a hematocrit tube. It has been found that this rod-like guide means 21 can be readily threaded into the bore of the hematocrit tube and will guide the plug-member 20 into securely seated pcsition. The plug-mernber 20, as we1l as the previously described plug4nembers 16 and 9, will form a standard bottom reference surface from which measurements can be accurately and reproducibly made.

lt should be understood that changes and modifications in the form, construction, arrangement, and combination of the several parts cf the hematocrit tube c1osure may be made and substituted for those herein shown and described without departing from the natura and principle 0f our invention.

Having thus described our invention, What We claim and desire to secure by Letters Patent is:

A c1osure for hernatocrit tubes and similar small gauge tubing, which closure comprises a unitary cup-like member formed of a resilient rubbery material and provided With an arcuate internal Wall adapted to fit snugly around an open end of the tubing, said cup-like member having a transverse bottom Wall adapted for spaced end-wise disposition across the open end cf the tubing, and a conical plug-forming element projecting upwardly from the bottom wall of the cup for tight-fitting disposition throughout a substantial portion cf its length within the bore of the tubing, said element being deforrnable so as to conform to the contour of the bore.

References Cited in the file of this patent UNITED STATES PATENTS 607,548 Pinkert July 19, 1898 1048,897 Schneider Dec. 31, 1912 1179622 Gavin Apr. 18, 1916 1949058 Leguillon Feb. 27, 1934 2394875 Rommel Feb. 12, 1946 2,680497 Miller June 8, 1954 2722257 Lockhart Nov. 1 1955

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US607548 *Dec 30, 1897Jul 19, 1898 Johann georg pinkert
US1048897 *Apr 12, 1910Dec 31, 1912Rudolf SchneiderClosure for tubes and the like.
US1179622 *Oct 4, 1915Apr 18, 1916Carr Lowrey Glass CompanyBottle.
US1949058 *Sep 29, 1932Feb 27, 1934Goodrich Co B FDispensing bottle stopper
US2394875 *Jun 21, 1943Feb 12, 1946Garrett Corp Aires Mfg CompanyMethod and means for testing tubes
US2680497 *Apr 24, 1950Jun 8, 1954Bernard C MillerGang of grease fitting caps
US2722257 *Feb 12, 1953Nov 1, 1955Compule CorpSampling tube equipment
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US3136416 *Nov 22, 1961Jun 9, 1964Dapol Plastics IncPackage for plastic articles
US3154074 *Oct 23, 1962Oct 27, 1964Lehn & Fink Products CorpInternal medicament applicator
US3180191 *Sep 26, 1961Apr 27, 1965Sweetheart Plasties IncPunch and die assembly for forming a cluster of covers
US3221939 *Jan 8, 1962Dec 7, 1965Barnes Hind International IncDisposable dispensers
US3302854 *Mar 30, 1965Feb 7, 1967Sweetheart PlasticsCluster of covers
US3307552 *Mar 25, 1963Mar 7, 1967Strawn Lillian TCatheter plug and shield device
US3428169 *Oct 12, 1964Feb 18, 1969Fur Montage Technik AnstaltFastener and package therefor
US3548506 *May 20, 1968Dec 22, 1970Francis H HarringtonFinger ring gauges
US4697340 *Oct 21, 1985Oct 6, 1987Molex IncorporatedMethod of manufacturing a carrier assembly
US4735312 *Aug 18, 1987Apr 5, 1988American Safety Razor CompanyRazor packaging
US4785935 *Feb 2, 1988Nov 22, 1988American Safety Razor CompanyRazor packaging
US4875582 *May 25, 1984Oct 24, 1989Molex IncorporatedCarrier assembly and method of manufacturing same
US5109979 *Feb 19, 1991May 5, 1992Innovation Services LimitedContainers and methods of manufacturing them
US5733308 *Mar 5, 1997Mar 31, 1998W. L. Gore & Associates, Inc.Surgical pledget dispensing system
US6558628Mar 5, 1999May 6, 2003Specialty Silicone Products, Inc.Compartment cover, kit and method for forming the same
US6613283Jan 2, 2001Sep 2, 2003Specialty Silicone Products, Inc.Vial pack cover, vial pack kit, and method for forming the vial pack cover
US6972112May 2, 2000Dec 6, 2005Specialty Silicone Products, Inc.Compartment cover, kit and method for forming the same
U.S. Classification215/320, 206/820, 206/446
International ClassificationG01N33/483
Cooperative ClassificationY10S206/82, G01N33/49
European ClassificationG01N33/49