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Publication numberUS2950717 A
Publication typeGrant
Publication dateAug 30, 1960
Filing dateMar 19, 1956
Priority dateMar 21, 1955
Publication numberUS 2950717 A, US 2950717A, US-A-2950717, US2950717 A, US2950717A
InventorsEdouard Bonet Bernard Maurice
Original AssigneeR K Price Associates Inc
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
US 2950717 A
Abstract  available in
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Claims  available in
Description  (OCR text may contain errors)

3Q, 1969 BQUET 2,950,717 AMEULES Filed March 19, 1956 INVENTOR B. M. E. BOUET ATTORNEYS it nite tates Patent (3 Patented Aug. 30, 1960 AMPULES Bernard Maurice Edouard Bouet, Paris, France, assignor to R. K. Price Associates, Inc., New York, N.Y.

Filed Mar. 19, 1956, Ser. No. 572,440

Claims priority, application France Mar. 21, 1955 2 Claims. (Cl. 128-218) The present invention relates to containers, and, more particularly, to hermetically closed containers.

This invention relates, still more particularly, to ampules containing liquid medicaments, intended to be used, in combination with hypodermic injectors of the type comprising a holder, on one extremity of which a hollow needle is mounted, said needle comprising a part projecting inside the holder and, in the other extremity, a movable pusher, the ampule being adapted to be placed in said holder, one of its ends being arranged to be pierced by said hollow needle inner part.

The known ampules of this type of hypodermic injectors are constituted by a glass tube closed at one of its ends by a thin wall and receiving in its other end a piston-plug usually made out of rubber, said thin wall being usually made either of rubber or of thin metal.

To make an injection with the known combination, one introduces the ampule in said holder with the thin wall brought against the hollow needle inner part, so as to be pierced by the same, while the piston-plug, closing the other end of the ampule, is brought against said pusher end.

The holder is usually provided with means to permit the operator to hold it with two fingers while the pusher is provided with means permitting to push the piston With the thumb.

The hypodermic injectors of the type specified are particularly useful for injections in the gums or in the bones, such injections requiring a strong push. The existing ampules to be used in combination with such injectors have different drawbacks.

It is very diflicult to keep the liquid sterile due to the difficulty of making the piston-tube assembly completely air-tight. The necessity of a good seal increases naturally the resistance ofi'ered by the piston, while it is slidably displaced along the tube.

It is also to be noted that certain liquids have a chemical action on the rubber.

Furthermore, due to high pressures developed inside the ampule during the injection, particularly when the same is made in a bone, the glass tube can burst which, in turn, can provoke accidents.

One of the objects of the present invention is to provide an ampule which has none of the drawbacks of the existing ampules.

Another object of the invention is to provide an ampule of thermoplastic material for use in connection with a hypodermic injector, the body of said ampule having a generally tubular form, the wall of the tube being pleated so as to form a bellows, the end walls of of said tube being transverse to the axis of said tube and being hermetically sealed under sterile conditions after the liquid medicament has been introduced inside said body.

It will be readily understood that such an ampule will be perfectly sterile due to the hermetical seal link. Furthermore, the resistance of certain thermoplastic materials avoids the possibility of bursting under pressure and, anyhow, the danger of accidents which could be produced by the particles of broken glass tubes.

The ampule according to the invention ofiers furthermore practically no resistance when compressed, due to the bellows shape of its tubular body. Due to this shape, the axial deformation is rendered easier than in any other direction.

In certain cases, it is desirable or necessary to be able to deform the ampule in the direction opposite to the one which determines the injection.

Another object of the invention is to provide a container or ampule of thermoplastic material for use in connection with medical fluid injecting or collecting devices, but in which one of the transverse end walls is constituted by a thick annular disk on the outer face of which a threaded blind hole is formed.

In the existing hypodermic injectors of the type specified, the inside end of the pusher rod is usually threaded, so that it can be threadably engaged in said blind threaded hole to permit the deformation of the bellows-like body of the ampule axially in both directions.

Another object of the invention is to provide a container of the general type specified above, but in which no liquid is enclosed before sealing, said container being intended to be used in combination with a blood sucking or a blood collecting device, said device comprising a hollow needle to pierce one of the transverse wall ends and an actuating member to threadably engage the blind hole in the opposite transverse thick end wall to first collapse the container by axial deformation of its bellowslike body and then to bring it back to its normal shape, while sucking blood inside the container.

Preferred embodiments of the invention will be hereinafter described with reference to the accompanying drawings, given merely by way of example and in which:

Fig. 1 shows a sectional view of an ampule according to the invention.

Fig. 2 is a similar view of a container forming, for instance, a liquid medicament ampule.

Fig. 3 is a sectional view showing a hypodermic injector in combination with the ampule-container of Fig. 2.

In Fig. 1, an ampule body constituted by a bellowslike tubular element 1 is closed hermetically at its extremities by two thin transverse walls 2 and 3, respectively. It must be well understood that to form an ampule one of said walls is sealed to the tubular body after a liquid medicament has been introduced in the tubular body under sterile conditions. The Fig. 1 shows, in fact, a complete ampule, to wit: the tubular body comprising the two transverse walls and a liquid medicament introduced, before scaling, in said body.

It must be also well understood that the thermoplastic material, the ampule body is made of, can be any conventional thermoplastic material such as polyethylene, polyvinyl chloride, etc. The specific nature of the thermoplastic material will be determined according to the liquid medicament in order to avoid every possible chemical reaction between the thermoplastic material and said liquid medicament.

Due to the bellows-like structure, the thermoplastic material is not necessarily very soft so that thermoplastic materials, other than polyethylene, may be used.

It will be clear that an ampule according to the invention is absolutely sterile, no leakage or penetration of air being possible.

In Fig. 2, the ampule or container 1a is of the same general construction as the one shown in Fig. 1, said ampule differing however from the one shown in Fig. 1 by the fact that the thin wall 2 is replaced by a thick disk-shaped wall 4 in which a threaded blind hole 5 is formed. This thick wall can be used for collapsing or extending the ampule axially as desired.

Fig. 3 shows a hypodermic injector comprising a holder body 9, one end of which is externally threaded for engagement with internal threads on a collar 15. At the other end of the holder 9 is mounted a hollow needle 10, one of the extremities 11 of said needle protruding inside the holder so as to pierce the thin walled extremity 3 of an ampule 1a mounted in said holder. The collar 15 at said one end of the holder 9 has an internally threaded, centrally disposed bore therethrough to receive and externally threaded sleeve 17 within which is mounted a push-rod 6, the extremity 8 of which is threaded so as to be engageable in the'internally threaded blind hole 5 in the thick end wall 4 of the ampule 1a. An abutment 7 is provided on the push rod 6 to limit the penetration of the threaded end 8 in the hole 5 and to increase the area of contact between the push-rod 6 and the thick wall 4 to permit said wall 4 to better resist mechanical stresses.

The holder 9 is held by two fingers engageable in the eyelets 12 and 13, while an eyelet 14 is provided on the push-rod 6 to receive the thumb.

To make a hypodermic injection, one has simply to push with the thumb on the push-rod 6, the abutment 7 of which compresses the ampule 1a so that the same collapses axially.

The combination of Fig. 3 offers the further advantage of permitting the use of an ampule 1a as an empty container for blood collection or for any other application in which a liquid is to be collected in a sterile container. For this purpose, after having placed an empty container of the type of Fig. 2 in the injector of Fig. 3, and after having screwed the push-rod 6 in the threaded hole 5, 1a is first flattened as for injection by pushing the rod 6 home to blow out any air it contains, whereupon the needle is introduced e.g. into a vein of the patient. To suck the blood into the empty container, it then suffices to draw slowly on the rod 6. It is to be noted that,

4 in this application, the use of a collapsible container according to the invention, has the essential advantage of avoiding any passage or introduction of external air in the blood or other collected liquid as with the usual blood sucking devices.

Alternatively, an ampule of which the liquid is merely an antiseptic having no chemical action on blood may be used for blood collection. In this case, the said liquid will be merely ejected from the container by fully flattening the same under compression by means of the pushrod before effecting the blood collection as exposed above.

What is claimed is:

1. A fluid container of thermoplastic material for use in connection with medical fluid injecting or collecting devices, said container comprising a tubular, bellows-like, body having an integral thin transverse end wall and an integral thick transverse wall, and a blind threaded hole formed in the outer face of said thick transverse wall.

2. The combination with a fluid-injecting or collecting device for medical use, said device comprising a holder for -a tubular element, a hollow needle protruding inside one end of said holder and an axially movable actuating member in the other end of said holder provided with a threaded end inside said holder; of a hermetically sealed fluid, sterile container of thermoplastic material comprising a tubular, bellows-like, body engaged in said References Cited in the file of this patent UNITED STATES PATENTS 1,604,224 Friedman Oct. 26, 1926 1,880,354 Mueller Oct. 4, 1932 2,667,165 Smith Jan. 26, 1954 2,696,212 Dunmire Dec. 7, 1954 2,717,598 Krasno Sept. 13, 5

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US1604224 *Jul 21, 1925Oct 26, 1926Friedman BenjaminSyringe
US1880354 *Jul 30, 1931Oct 4, 1932Herman C MuellerFluid gun
US2667165 *Mar 19, 1952Jan 26, 1954Smith Arthur EDisposable syringe
US2696212 *Sep 28, 1951Dec 7, 1954Russell P DunmireHypodermic syringe
US2717598 *Nov 21, 1952Sep 13, 1955Louis R KrasnoHypodermic syringe
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3099264 *Jul 11, 1962Jul 30, 1963Hubbard Raymond EDisposable syringe and compression device therefor
US3161194 *Feb 4, 1963Dec 15, 1964Samuel L ChapmanHypodermic syringe
US3166070 *Dec 5, 1961Jan 19, 1965Lapis Engineering Company LtdSyringe for hypodermic injection
US3190619 *May 27, 1963Jun 22, 1965Union Carbide CorpFluid mixing container assembly
US3496937 *May 18, 1967Feb 24, 1970John E BalsonHypodermic syringe
US4392491 *Jul 29, 1981Jul 12, 1983Colpo Company LimitedInjector
US4500308 *Nov 16, 1982Feb 19, 1985Bioresearch Inc.Autotransfusion device with twisted collection bag
US5308322 *Apr 19, 1993May 3, 1994Tennican Patrick OCentral venous catheter access system
US5344397 *Jun 26, 1992Sep 6, 1994Advanced Surgical, Inc.Cholangiogram catheter
US5592948 *Jul 19, 1995Jan 14, 1997Gatten; Ronald A.Self contained vial for drawing, storing, sealing and identifying a fluid sample
US5683369 *Apr 12, 1994Nov 4, 1997Tsukada Medical Research Co., Ltd.Bellows type container charged with liquid medicine
US5836922 *Jun 21, 1996Nov 17, 1998Bernd HansenContainer for delivery of flowable material
US6077252 *Sep 17, 1997Jun 20, 2000Siegel; RobertSingle or multiple dose syringe
US6083204 *Sep 29, 1998Jul 4, 2000Malerba; RichardMethod and apparatus for gravity-fed intravenous infusion
US7011650Jan 6, 2003Mar 14, 2006Paradigm Medical, LlcMultiple-dose syringe with collapsible container
US7077826 *Jan 23, 2003Jul 18, 2006Robin Scott GraySyringe and method of using
US9180252Mar 15, 2013Nov 10, 2015Bayer Medical Care Inc.Bellows syringe fluid delivery system
US9498570Apr 23, 2012Nov 22, 2016Bayer Healthcare LlcBladder syringe fluid delivery system
US20030167041 *Jan 6, 2003Sep 4, 2003Rosoff Jack P.Multiple-dose syringe
US20050038315 *Aug 12, 2003Feb 17, 2005Slo-Flo Ltd.Motorized syringe particularly useful for intra-uterine insemination
DE19545838A1 *Dec 8, 1995Jun 12, 1997Karlheinz Dr Med RothenbergerHypodermic
EP1225937A1 *Sep 7, 2000Jul 31, 2002Tri-Med International, LLCMultiple-dose syringe
WO1984001900A1 *Nov 15, 1983May 24, 1984Bioresearch IncAutotransfusion device with twisted collection bag
U.S. Classification604/214, 604/216
International ClassificationA61J1/06
Cooperative ClassificationA61J1/062
European ClassificationA61J1/06B