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Publication numberUS3037495 A
Publication typeGrant
Publication dateJun 5, 1962
Filing dateJul 17, 1959
Priority dateJul 17, 1959
Publication numberUS 3037495 A, US 3037495A, US-A-3037495, US3037495 A, US3037495A
InventorsNaz John F
Original AssigneeNaz John F
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Biopsy device
US 3037495 A
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Description  (OCR text may contain errors)

MSW@ NN j \L im. wi NNW N www "Liv NN June 5, 1962 F www fw Naz: E: "A \rrr/ l WML A WN NN NL ice 3,037,495 BIOPSY DEVICE John F. Naz, 2826 Orange Grove, Waterford, Mich. Filed July 17, 1959, Ser. No. 827,912 4 Claims. (Cl. 128-2) This invention relates to an improved biopsy device for removing surface cell material from a recessed portion of a living organism, and more particularly but not necessarily exclusively to an improved device of this character for obtaining biopsy samples from the uterine cervix.

One important object of the present invention is to provide an improved biopsy device for removing loosely held tissue from the surface of a recessed portion of a body cavity.

Other objects are: To provide an improved device for obtaining biopsy samples from the uterine cervix; to provide an improved biopsy device for securing surface cell samples from within a selected portion of a body cavity and protecting them from contamination as they are withdrawn from the cavity; and in generalkto provide an improved biopsy device of this character which is reliable in operation, simple to use and relatively inexpensive to manufacture.

The foregoing and other objects and advantages of the present invention will become apparent in the following detailed description of a preferred embodiment thereof, taken in conjunction with the drawing, wherein:

FIGURE l is a longitudinal sectional view of a biopsy device according to the invention, showing the device in one operative position;

FIGURE 2 is a longitudinal sectional view generally similar to the view of FIGURE l, but showing the device in a second operative position;

FIGURE 3 is a cross-sectional view taken along the line 3 3 of FIGURE l; and

FIGURE 4 is a fragmentary front elevational view showing the construction of the tissue collecting diaphragm, the View being taken in the direction of the arrow 4 of FIGURE 2.

A biopsy device according to a preferred embodiment of the invention and as shown in the drawing comprises three rigid parts, a collar 10, a plunger 12, and a sleeve 14, which may be made of metal, plastic or any other desired relatively rigid material, and which are arranged to hold and manipulate a flexible diaphragm 16 for contacting the surface from which the tissue sample is to be taken.

The collar is in the form of an elongated tube having a relatively small diameter rear portion 18, a relatively large diameter front portion 20, and a tapering intermediate portion 22. The collar 10 is preferably made substantially longer than the length of the body cavity it is desired to investigate in order to permit easy manipulation of the device from outside of the body.

The plunger 12 is slidably fitted within the collar 10 and includes a relatively narrow shaft portion 24 and a piston-like front portion 26. A pair of finger grips 28 are xed at the rear of the collar 10, and the plunger 12 carries a thumb grip, or ring 30 to facilitate manual actuation of the plunger in the collar. A style 32 is xed on and projects from the front end of the plunger 12, and is dimensioned to fit within the cervix. The end of the style 32 is preferably smoothly rounded and may be slightly enlarged to form a knob 34 if desired.

The front end portion 26 of the plunger carries a diametrically arranged bar 36, which is fixed to the plunger, and extends radially outwardly through a pair of slots 38 in the collar 10 for limiting the travel of the plunger relative to the collar. At the forwardmost position of the plunger 12 relative to the collar the style 32 projects, as shown in FIGURE 1, substantially its full length beyond the front end of the collar. When the plunger 12 is fully retracted the style 32 is fully withdrawn and does not project beyond the end of the collar.

The sleeve 14 is slidably fitted over the enlarged front end portion 20 of the collar and is provided with slots 40, which are aligned with the slots 38 of the collar. The bar 36 extends also through the sleeve slots 40. The sleeve 14 also carries an external annular flange 42 at its front end for engaging and retaining the diaphragm 16. The slots 4t) in the sleeve are slightly shorter than the slots 38 in the collar so that when the plunger 12 is fully retracted the bar 36 engages the rear edges of the slots 40 and retracts the sleeve 14 a short distance, say about 1/s" rearwardly on the collar 10 to draw the diaphragm 16 hat and stretch it slightly across the end of the collar it).

The diaphragm 16 may be made of rubber or any other desired relatively soft elastomeric material and has a reinforcing and retaining ring 44 around its outer periphery, which snap-spring engages behind the ange 42 of the sleeve for removably retaining the diaphragm on the device, The outer surface 46 of the diaphragm is of cratered or dimpled configuration, as perhaps best shown in FIG. 4, and includes a plurality of closely spaced cup-like indentations 48, which are drawn partly open as the diaphragm is str-etched, and which return to a position of maximum closure when the diaphragm.

retracts.

In operation, the diaphragm 16 is fitted over the front end of the sieeve 14 with the plunger 12 retracted so that the diaphragm is positioned as shown in FIGURE 2 across the front end of the collar 10 and the sleeve 14. The device is then placed in position and the diaphragm is held against the cervix by manual pressure on the finger grips 28. The plunger is then advanced by means of the thumb grip 30 to drive the style 32 into the cervix. The style 32 carries the diaphragm 16 into engagement with the inner Wall of the cervix with a soft rubbing action during which the cup-like formations 48 on the surface of the diaphragm pick up and retain cell samples from the cervical wall. The plunger 12 is then retracted and the instrument is withdrawn. Due to its natural elasticity the diaphragm 16 retracts itself with the plunger, and as the plunger 12 approaches its fully retracted position, the bar 36 engages the slots 40 and retracts the sleeve 14 slightly to hold the diaphragm in a lightly stretched flat position across the open end of the collar as shown in FIGURE 2. The central portion of the diaphragm 16 and the biopsy material thereon are thus protected from contamination through contact with the walls of the vagina as the diaphragm is withdrawn.

The collected cell material on the surface of the diaphragm may be dabbed on a microscope slide or otherwise prepared as desired for cytological or other studies.

What is claimed is:

l. A biopsy device for obtaining cell samples comprising a tubular housing, a plunger slidable within said housing, a sleeve itted externally on said housing and slidable relative thereto, an elastomeric cell receiving member having a roughened surface, means carried by said sleeve for removably retaining said elastomeric cell receiving member in a position over one end of said housing, means for retracting said sleeve relative to said housing in response to relative movement between said housing and said plunger, and means carried by said plunger for engaging said elastomeric cell receiving member and extending it beyond said one end of said housing when said plunger is advanced relative to said housing to thus move said roughened surface of the elastomeric cell receiving member into contact with the cell samples to be obtained.

2. A biopsy device for obtaining cervical surface cell samples comprising a tubular housing, a plunger longitudinally slidable within said housing, limit means for limiting relative movement between said housing and said plunger, a sleeve fitted externally on said housing and slidable relative thereto, an elastomeric cell receiving diaphragm having a roughened surface, means carried by said sleeve for removably retaining said elastomeric diaphragm across one end of said housing, and a style carried by said plunger for engaging said diaphragm retained by said sleeve and movable beyond said one end of said housing for stretching the diaphragm into the cervix when said one end of said housing is held against the cervix and said plunger is advanced relative to said housing.

3. A biopsy device for obtaining cervical surface cell samples comprising a tubular housing, a plunger longitudinally slidable within said housing, limit means for limiting relative movement between said housing and said plunger, a sleeve fitted externally on said housing and slidable relative thereto, an elastomeric diaphragm having a roughened surface, means carried by said sleeve removably retaining said elastomeric diaphragm across one end of said housing, and a style carried by said plunger for engaging said diaphragm retained by said sleeve and movable beyond said one end of said housing for stretching the diaphragm into the cervix when said one end of said housing is held against the cervix and said plunger is advanced relative to said housing, and means for stretching the diaphragm lightly across said one end of said housing in response to full retraction of said plunger relative to said housing.

4. A biopsy device for obtaining cervical surface cell sa-mples comprising a generally tubular housing having an open forward end and a longitudinally extending aperture adjacent thereto, a plunger longitudinally slidable within said housing, a projection fixed to said plunger and extending through said aperture for limiting movement of said plunger relative to said housing, a style carried by said plunger at the forward end thereof and movable therewith between a retracted position in which said style is fully Within said housing and an advanced position in which said style projects forwardly from said housing, a sleeve slidably mounted exteriorly on said housing adjacent to the forward end thereof, said sleeve having a longitudinal slot therein which is Shorter than said aperture in said housing, said projection on said plunger also extending through said slot, said slot being positioned in said sleeve so that during a terminal portion of the retracting travel of said plunger said projection engages the rear end of said slot and retracts said sleeve to a position in which its front end is spaced rearwardly from the front end of said housing, a cell receiving elastomeric diaphragm having a roughened surface, said sleeve also having a retaining iiange extending around its front end removably receiving said cell receiving elastomeric diaphragm and supporting it across the open front end of said housing.

References Cited in the tile of this patent UNXTED STATES PATENTS 2,591,927 Gladstone Apr. 8, 1952 2,701,559 Cooper Feb. 8, 1955 2,710,000 Cromer et a-l. June 7, 1955 2,831,478 Uddenberg et al. Apr. 22, 1958 2,847,990 Ayre Aug. 19, 1958 FOREIGN PATENTS 215,350 Germany Feb. 13, 1908 894,606 Germany Oct. 26, 1953

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2591927 *Oct 6, 1948Apr 8, 1952Gladstone Sidney AObtaining tumor tissue specimen
US2701559 *Aug 2, 1951Feb 8, 1955Cooper William AApparatus for exfoliating and collecting diagnostic material from inner walls of hollow viscera
US2710000 *Feb 19, 1952Jun 7, 1955Cromer Jeremiah KeithCutting instrument
US2831478 *Oct 31, 1955Apr 22, 1958Thoren Herbert AlfredApparatuses for observing and measuring of pressures within organs of the human body
US2847990 *Mar 20, 1956Aug 19, 1958Ernest Ayre JamesInstrument for obtaining cells for cytodiagnosis
*DE215350C Title not available
DE894606C *Jan 10, 1943Oct 26, 1953Karl KarolVorrichtung zum Einfangen, Zerkleinern und Entfernen von Fremdkoerpern (Steinen, Konkrementen) aus Hohlraeumen des menschlichen Koerpers
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3247841 *May 29, 1961Apr 26, 1966Cook Galen BDiagnostic method
US3394699 *Jul 22, 1965Jul 30, 1968Panto Entpr IncInstrument for obtaining a biopsy specimen
US3664328 *Apr 28, 1971May 23, 1972Moyle Henry Dinwoodey JrCancer test specimen gathering device
US3800781 *May 30, 1972Apr 2, 1974K ZaluckiSpecimen-taking device
US4311140 *Jun 4, 1979Jan 19, 1982Henry BridgmanVacuum curet having an improved curetting opening
US4467816 *Jul 22, 1981Aug 28, 1984Battelle-Institut E.V.Device for collecting cell material
US4763670 *Sep 19, 1986Aug 16, 1988Microvasive, Inc.Microbiological specimen sampling device
US4945921 *Dec 30, 1987Aug 7, 1990Okimoto Paul MBody cavity specimen collecting and testing apparatus
DE1541132B1 *Dec 27, 1966Mar 4, 1971Hollister IncGebaermutterhals-Probenehmer
EP0004318A2 *Mar 8, 1979Oct 3, 1979Battelle-Institut e.V.Device for collecting cellular material from the endometrium
Classifications
U.S. Classification600/572
International ClassificationA61B10/02, A61B10/00
Cooperative ClassificationA61B10/0291
European ClassificationA61B10/02U