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Publication numberUS3066670 A
Publication typeGrant
Publication dateDec 4, 1962
Filing dateMay 27, 1958
Priority dateMay 31, 1957
Also published asDE1174020B
Publication numberUS 3066670 A, US 3066670A, US-A-3066670, US3066670 A, US3066670A
InventorsFerdinand B Stauffer
Original AssigneeStato A G
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Hypodermic injection apparatus
US 3066670 A
Abstract  available in
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Claims  available in
Description  (OCR text may contain errors)

Dec. 4, 1962 F. B. s'rAUr-'FER HYPODERMIC INJECTION APPARATUS Filed May 27, 1958 Arr-7 I:

United States Patent .Olitice 3,066,670 Patented Dec. 4, 1962 3,066,670 HYPODERMTS INJECTHN APPARATUS Ferdinand B. Staulier, Lucerne, Switzerland, assignor to Stato A.G., Zurich, Switzerland, a firm Filed May, 27, 1958, Ser. No. 738,121 Claims priority, application Germany May 31, 1957 6 Claims. (Cl. 12S-218) This invention relates to a hypodermic injection apparatus including a spring loaded operating plunger and a replaceable ampoule dischargeable by operation of the plunger.

Hypodermic injection apparatus is known which has an operating plunger provided with a rod permitting retraction or" the plunger in order to recharge the apparatus. The plunger projects in the direction of its free end out of the casing, in loaded position of the plunger. The plunger projects a distance at least equal to the working stroke of the plunger. Due to its extended length the apparatus is inconvenient to carry and to use. A further disadvantage is that the plunger rod can be moved manually during the working stroke. This is not desirable in an apparatus which may be manipulated by inexperienced persons. Some prior known hypoderrnic injection devices require means separate from the apparatus for retracting an operating plunger into a spring loaded position. The necessity of using retraction means separate from the apparatus is undesirable since such means are subject to being mislaid or lost and may be replaced by unsuitable substitute retraction means.

According to the present invention, the apparatus employs a spring loaded plunger which is engaged by locking means in a spring loaded retracted position. The plunger is adapted when released from said locking means to perform automatically the insertion of the needle into the esh of a person and the injection of uid subcutaneously in optimum location therein. The fluid is carried in an ampoule which is exchangeably carried in the apparatus. A wholly concealed needle is carried by the ampoule. The ampoule is disposed in a cylindrical casing of the apparatus in coaxial alignment with the plunger which abuts one side or end of the ampoule. The other end of the ampoule is closed and concealed by a cap detachably mounted on the casing at the forward end ot the needle.

In an injection apparatus working automatically after release of the plunger it is essential to avoid the disadvantage of certain known apparatus in which liquid injection occurs simultaneously with the piercing of the flesh by the needle and in which the discharge of fluid occurs vproportionally to the advance of the needle into the flesh.

This disadvantage is avoided in the present invention since the relatively small quantity of liquid in the ampoule is mainly injected at the end of the piercing forward movement of the needle. Thus the liquid is deposited at sutlicient and proper depth below the skin.

In the present invention, the operating plunger is completely accommodated within the casing in ready condition for use. The plunger then engages the container of liquid in the ampoule on which the pointed, tubular needle is ixed. The needle is disposed separate from the liquid. The ampoule is disposed inside of a removable cap on the casing. The cap has a calyx-like form with an opening in its bottom or forward end for passage of the needle therethrough. The opening in the cap is closed by a penetrable stopper fitted in the opening and holding the forward end of the needle in partial penetration therein. The cap is so shaped and dimensioned that it can be used in detached condition to retract the plunger for manual resetting of the same in spring loaded position.

It is therefore a principal object of the invention to provide a hypodermic apparatus having a spring loaded plunger and an internally contained exchangeable ampoule, the plunger being positioned to eject a tubular needle from the ampoule and to eject iluid through the needle in predetermined sequence.

It is another object to provide a hypodermic apparatus of the character described with locking means for retaining the spring loaded plunger in retracted position, said locking means being manually operable to release the plunger.

A further object is to provide a hypodermic apparatus in which a locking means for a spring loaded plunger is releasable only by exerting pressure manually against a counteracting spring means.

A. still further object is to provide a hypodermic apparatus in which spring means is provided'to brake outward movement of the spring loaded plunger when released and near the end of its outward movement.

Another object is to provide a removable cap for an ampoule of a hypodermic apparatus, the cap having a tapered form and adapted for retracting a plunger against spring tension for resetting the plunger in operating condition.

Another object is to provide a hypodermic apparatus of the character described wherein the cap has a stopper retaining the pointed end of a needle, the stopper being penetrable by the needle upon release of the spring loaded plunger for ejection of the needle.

Other objects of the invention will become apparent from the following detailed description taken in connection with the accompanying drawings, in which FIG. l shows the injection apparatus in axial section;

FIG. 2 is a fragmentary perspective View with portions broken away, and i FIG. 3 is a top view.

The operating device has a cylindrical casing 1 which is partly covered by a milled tubular grip 2 made of synthetic resin, and is closed at its one end by a calyxlike cap 3 detachably mounted by means of a bayonet catch 4 and provided with an aperture 6 in its bottom 5. In the casing, a tubular body 7 is guided for axial displacement and has coaxially secured thereto -a hollow Iplunger 8 which projects toward the cap side, its projecting portion being radially spaced from the tubular body 7. Three leaf springs 10 are secured to a cylindrical part 9 of the body 7 for axially extending on the side opposite to the plunger through the aperture of a conical ring 11 which is mounted in the casing 1 to form an annular shoulder adapted to engage the free ends 12 of the spring 10, which ends are inwardly inclined for co-operation with the cone of the ring 11 and are bent back on the outer side to form each a catch for engaging the shoulder.

The casing 1 carries on its end opposite to the cap 3 an operating socket 13 which is turnable and axially displaceable and accommodates a locking and releasing device. This device comprises an assembling ring 14 having three axially extending tongues 15 the free ends of which are bent inwardly for connecting a locking ring 16, a cap 17 made of synthetic resin and a sleeve 18 extending axially into the hollow plunger 8 with the socket 13. A coil spring 19 bears with one end against the casing 1 and with the other end against the locking ring 16, Vwhile coil spring 2i) bears against the ring 11 of the casing 1 and the body 7, respectively, for operating the plunger 8. A screw 21 secured in the bottom 8 of the plunger 8 penetrates through the bottom of the sleeve 18 and extends coaxially therein over a length of a little more than the length of the plunger stroke. A comhead 22 of the screw 21 `and said sleeve bottom for 1? damping the plunger stroke shortly before its end. Tue other end of the Sleeve 1S is closed by a cap 24 pressed into the sleeve.

The circumference of the locking ring 16 has three equal recesses 25 equally spaced from each other and each having two portions which are different in axial width. Into each of said recesses 25 projects an inwardly bent lug 26 provided at the end of the casing 1. The breadth of the lug is a little less than that of each of the two recess portions, the axial width of one portion being just sufficient to receive the lug 26, so that practically no axial displacement of the locking ring 16 relative to the casing 1 is allowed, while the axial width of the other recess portion is such that the axial displacement of the ring 16 allows release of the leaf springs 10 from their engagement with the shoulder 11. The releasing of the springs occurs when the socket 13 together with the locking ring 16 and the assembling ring 14 is pushed against the effect of the spring 19 toward the casing 1, whereby the catch ends 12 of the leaf springs 10 approach each other radially of the casing at the inner end of the assembling ring 14 and are thus disengaged, so that the compressed plunger loading spring 20 will expand.

The injection ampoule which is exchangeably accommodated in the above described operating device comprises a cylindrical barrel 27 for medicinal liquid. The barrel is made of transparent unbreakable synthetic resin and has a head 28 wherein an injection needle 29 is coaxially secured. The needle projects on both sides beyond the head. The liquid 30 is confined within the barrel 27 between two movably disposed Vstopples 31 and 32. The stopple 32 is slightly spaced from the head and can be perforated by the inner tapered end 33 of the needle. The outer end or piercing point 34 of the needle sticks in a rubber stopper 35 which closes the muzzle of the needle as well as the aperture in the bottom of a cylindrical protecting sleeve 36 axially guided on the head 28 and enclosing the needle 29. The sleeve 36 has a contracted end behind the head preventing removal of the sleeve. For disposing the described ampoule in the casing 1 the cap 3 must be removed. The free barrel end projecting beyond the stopple 31 is then shifted upon the plunger 8 so that the same bears against said stopple. When again mounting the cap 3 it must be shifted upon the protecting sleeve 36 for being closed, whereby the stopper 35 projects into the aperture 6 in the bottom of the cap 3 and closes the same.

The hypodermic injection aparatus as described is' manipulated in the following manner: Either the apparatus is put with its bottom 5 of the cap 3 directly upon the injection spot on the skin or it is held in the hand tightly thereabove in such a way that the forefinger and the middle-finger bear against the shoulder 37 of the cap 3 for parrying the stroke reaction. Before this, the apparatus will be brought into ready condition by turning the locking ring 16 out of its locking position, whereby the narrow recess portions are turned off the lugs 26 so as to bring the wide recess portions in alignment with said lugs, for which purpose markings may be provided on the outer cylindrical surface of the socket 13 and the adjacent end of the grip 2. The socket 13 'can now be pressed down into the casing 1, whereby the inner end of the assembling ring 14 releases the leaf springs 10, 12 `from engagement with the shoulder of the ring 11. The compressed coil spring 20 is thereby released to expand. It pushes the tubular body 7 together with the plunger 8 toward the cap v3. The sudden thrust of the plunger on the stopple 31 is transmitted by the liquid 30 upon the stopple 32 which will be displaced toward the head 28 and perforated by the tapered end 33 of the needle. The thrust is then transmitted from the stopple 32 over the head upon the needle 29 which perforate's the unperforated outer portion of the stopper 35. Liquid can now issue at the needle point 34. Since the .liquid friction -arising in the narrow bore of the needle is considerable, liquid will lflow rather slowly, while on the other hand the thrust of the plunger 8 causes the Vbarrel 27 to be shifted in the sleeve 36. The wetted needle 29 penetrates very quickly through the aperture 6 into the flesh so that the main quantity of the liquid contained in the barrel 27 will be deposited in the depth of the`\esh to which the needle point 34 has penetrated. The injection of the liquid thereby occurs during the remaining stroke of the plunger 8 as the stopple 31 `approaches the stopple 32. Toward the end of the stroke of the plunger the head 22 of the screw 21 abuts against the damping spring 23 which together with the spring 19 brakes the stroke.

By removing the cap 3 the exhausted ampoule can easily be removed from the apparatus. Before the operating spring 20 will again be restored into loaded position and before a new ampoule will be mounted in the apparatus the socket 13 should be turned into locking position.

For reloading the spring 20 the cap 3 will be disposed with its large open end upon a base thus disposing the bottom 5 uppermost. The bottom is slightly countersunk and covered by a ring 38 consisting of synthetic resin, upon which the plunger 8 is placed with its free end 8 projecting out of the open casing 1. By depressing the casing the plunger 8 will be restored into its loaded position shown in FIG. l, in which the catch ends 12 of the leaf springs 10 pass through the conical opening of the ring 11 and engage its shoulder, thus preventing expansion of the tensioned spring 20. The new ampoule can then be inserted in the apparatus without endangering its internal sterility. After the cap 3 is closed the apparatus is again in locked ready condition land can be stored in such condition.

What I claim is:

1. A hypodermic injection apparatus, comprising a casing, a plunger slidably held and laxially movable in said casing, locking means releasably engaging and holding said plunger in retracted position, a spring mounted within said casing and acting between abutment portions of said casing and said plunger for forcing the latter away from said retracted position thereof, an ampoule axially slidably mounted in the casing and carrying a tubular needle, said ampoule being removably and exchangeably disposed in said casing, a cap detachably connected to said casing for replaeeably holding said ampoule in the casing, a stopper fitted in said cap and closing a leading end of ysaid needle, said stopper being penetratable by said needle, said cap being apertured to permit passage of said needle therethrough and said needle being xedly mounted in the forward end of said ampoule so that movement of the ampoule forwardly -will cause said needle to pierce said stopper, said ampoule containing a body of liquid, a movable stopple disposed in the ampoule at one end of said body of liquid remote from said needle, said plunger having a leading end -abutting said stopple for driving the same during an operating stroke of the plunger, whereby release of said plunger by said locking means moves said body of liquid to drive said needle through said stopper whereupon further movement of said plunger `ejects said liquid through said needle near the end of said operating stroke.

2. A hypodermic injection apparatus, comprising a casing, a plunger slidably held and axially movable in said casing, locking means releasably engaging and holding said plunger in retracted position, a spring mounted within said casing and acting between abutment portions of said casing and said plunger for forcing the latter away from said retracted position thereof, an ampoule axially slidably mounted in the casing and carrying a tubular needle, said ampoule being removably and exchangeably disposed in Isaid casing, a cap detachably connected to said casing for replaceably holding said ampoule in the casing, a stopper fitted in said cap and closing a leading end of said needle, said stopper being penetratable by said needle, said cap being apertured to permit passage of said needle therethrough and said needle being lixedly mounted in the forward end of said ampoule so that movement of the ampoule forwardly will cause said needle to pierce said stopper, said ampoule containing a body of liquid, .a movable stopple disposed in the ampoule at one end of said body of liquid remote from said needle, said plunger having a leading end abutting said stopple for driving the same during an operating stroke of the plunger, whereby release of said plunger by said locking means moves said body of liquid to drive said needle through said stopper whereupon further movement of said plunger ejects said liquid through said needle near the end of said operating stroke, said locking means including a spring catch, said casing having a portion engaged by said spring catch, said spring catch being movable radially inwardly in the casing for releasing said plunger, and a member movably disposed in said casing for disengaging said spring catch from said portion of the casing.

3. A hypodermic injection apparatus, comprising a casing, a plunger slidably held and axially movable in said casing, locking means releasably eng-aging and holding said plunger in retracted position, a spring mounted vwithin said casing and acting between abutment portions of said casing and said plunger for forcing the latter away from said retracted position thereof, an ampoule axially slidably mounted in the casing and carrying a tubular needle, said ampoule being removably and exchangeably disposed in said casing, a cap detachably connected to said casing for replaceably holding said ampoule in the casing. ya stopper fitted in said cap and closing a leading end of said needle, said stopper being penetratable by said needle, said cap being apertured to permit passage of said needle therethrough and said needle being xedly mounted in the forward end of said ampoule so that movement of the ampoule forwardly will cause said needle to pierce said stopper, said ampoule containing a body of liquid, a movable stopple disposed in the ampoule at one end of said body of liquid remote from said needle, said plunger having a leading end abutting said stopple for driving the same during an operating stroke of the plunger, whereby release of said plunger by said locking means moves said body of liquid to drive said needle through said stopper whereupon further movement of said plunger ejects said liquid through said needle near the end of said operating stroke, said locking means including a spring catch, said casing having a portion engaged by said spring catch, said spring catch being movable in the casing for disengaging said spring `catch from said portion of the casing, said plunger and said member each having abutment means thereon, and spring means disposed between said abutment means of said plunger and said member and effective only near the end of said operating stroke for braking movement of the plunger while liquid is ejected through the needle.

4. A hypodermic injection apparatus, comprising a casing, a plunger slidably held and axially movable in said casing, locking means releasably engaging and holdingsaid plunger in retracted position, -a spring mounted within said casing and acting between abutment portions of said casing and said plunger for forcing the latter away from said retracted position thereof, an ampoule axially slid-ably mounted in said casing and carrying a tubular needle, said ampoule being removably and engageably disposed in said casing, a cap detachably connected to said casing for replaceably holding said ampoule in the casing, a stopper iitted in said cap and closing a leading end of said needle, said stopper being penetratable by said needle, said cap being apertured to permit passage of said needle therethrough and said needle being lixedly mounted in the forward end of said ampoule so that movement of the ampoule forwardly will cause said needle to pierce said stopper, said ampoule containing a body of liquid, a movable stopple disposed in the ampoule at one end of said body of liquid remote form said needle, said plunger having a leading end Iabutting said stopple for driving the same during an operating stroke of the plunger, whereby release of said plunger by said locking means moves said body of liquid to drive said needle through said stopper whereupon further movement of said plunger ejects said liquid through said needle near the end of said operating stroke, said locking means including -a spring catch, said casing having a portion engaged by said spring catch, said spring catch being movable in the casing for releasing said plunger, a member axially movably disposed in the casing for disengaging said spring catch from said portion of the casing, said plunger and said member each having abutment means thereon, and spring means disposed between said abutment means of said plunger and said member and effective only near the end of said operating stroke for braking movement of the plunger while said liquid is ejected through said needle, a turnable socket disposed on said casing and operatively connected to said member, further abutment means on each of said member and said casing, a further spring located between Ysaid further abutment means on said member and said casing for supplementing the rst named spring means in braking movement of the plunger at the end of its operating stroke, said further spring opposing movement of said member in disengaging said spring catch from said portion of the casing.

5. A hypodermic injection apparatus, comprising a casing, a plunger slidably held and axially movable in said casing, locking means releasably engaging and holding said plunger in retracted position, a spring mounted within said casing and acting between abutment portions of said casing and said plunger for forcing the latter away from said retracted position thereof, an -ampoule axially slidably mounted in said casing and carrying a tubular needle, said ampoule being removably and exchangeably disposed in said casing, a cap detachably connected to said casing for replaceably holding said ampoule in the casing, a stopper fitted in said cap and closing a leading end of said needle, said stopper being penetratable by said needle, said cap being apertured to permit passage of said needle therethrough and said needle being xedly mounted in the forward end of said ampoule so that movement of the ampoule forwardly will cause said needle to pierce said stopper, said ampoule containing -a body of liquid, a movable stopple disposed in the ampoule at one end of said body of liquid remote from said needle, said plunger having a leading end abutting said stopple for driving the same during an operating stroke of the plunger, whereby release of said plunger by said locking means moves said body of liquid to drive said needle through said stopper whereupon further movement of said plunger ejects said liquid through said needle until the end of said operating stroke, said locking means including a spring catch, said casing having a portion engaged by said spring catch, said spring catch being movable in the casing for releasing said plunger, a member axially movably disposed in the casing for disengaging said spring catch from said portion of the casing, said plunger and said member each having abutment means thereon, and spring means disposed between said abutment means of said plunger and said member and effective only near the end of said operating stroke for braking movement of the plunger while said liquid is ejected through said needle, a turntable socket disposed on said casing and operatively connected to said member, further abutment means on each of said member and said casing, a further spring located between said further abutment means on said member and said casing for supplementing the first n-amed spring means in braking movement of the plunger at the end of its operating stroke, said further spring opposing movement of said member in disengaging said spring catch from said portion of the casing, and another penetratable stopple seated in said ampoule at a forward end of said ibody of liquid adjacent a rear end of said needle, said other stopple being penetratable by the rear end of the needle at the beginning of said operating Vstroke of said plunger for providing access of said liquid into the needle.

6. A hypodermic injection apparatus, comprising a casing, a plunger slidably held and axially movable in said casing, locking means releasably engaging and holding said plunger in retracted position, a spring mounted within said casing and acting between abutment portions of said casing and said plunger for forcing the latter away from said retracted position thereof, an ampoule axially slidably mounted in said casing and carrying a tubular needle, said ampoule being removably and exchangeably disposed in said casing, a cap detachably connected to said casing for replaceably holding said ampoule in the casing, 4a stopper fitted in said cap and closing a leading end of said needle, said stopper being penetratable by said needle, said cap being apertured to permit passage of said needle therethrough and said needle being xedly mounted in the forward endk of said ampoule so that movement of the ampoule forwardly will cause said needle to pierce said stopper, said ampoule containing a body of liquid, a movable stopple disposed in the :ampoule at one end of said body of liquid remote from said needle, said plunger having a leading end abutting said stopple for driving the same during -an operating stroke of the plunger, whereby release of said plunger by said locking means moves said bodyV of liquid to drive said needle through said stopper whereupon further movement of said plunger ejects said liquid through said needle near the end of said operating stroke, said locking means including a spring catch, said casing having a portion engaged by said spring catch, said spring catch being movable in the casing for releasing said plunger, a member axially movably disposed in the casing for disengaging said spring catch `from said portion of the casing, said plunger and said member each having abutment means thereon, and 'spring means disposed between said abutment means of said plunger and said member and effective only near the end of said operating stroke for braking movement of the plunger while said liquid is ejected through said needle, a turnable socket disposed on said casing and operatively connected to said member, further abutment means on each of said member and said casing, a further spring located between said further abutment means on said member -and said casing for supplementing the rst named spring means in braking movement of the plunger at lthe end of its operating stroke, said further spring opposing movement of said member in disengaging said spring catch from said portion of the casing, and another penetratable stopple seated in said ampoule vat a forward end of said body of liquid adjacent a rear end of said needle, said other stopple being penetrable by the rear end of the needle at the beginning of said operating stroke of said plunger for providing access of said liquid into said needle, said socket having recessed portions therein, said casing having at least one lug projecting into one of said recessed portions to prevent axial movement of said mem-ber for releasing said spring catch, said socket being turnable with said member to disposed said lug in another of said recessed portions and movable against tension in said other spring means to release said spring catch to permit forward operating movement of said plunger.

References Cited in the le of this patent UNITED STATES PATENTS 1,179,560 Reed,y Apr. 18, 1916 2,762,369 Venditty Sept. 11, 1956 2,832,339 Sarnoff et al Apr. 29, 1958 2,856,924 Rockwell ,-aa Oct. 21, 1958

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US1179560 *Nov 6, 1914Apr 18, 1916Harry L ReedContainer.
US2762369 *Sep 7, 1954Sep 11, 1956Scherer Corp R PHypodermic injector with adjustable impact plunger
US2832339 *Sep 2, 1953Apr 29, 1958Potter Pharmaceutical CorpHypodermic injector
US2856924 *Nov 9, 1954Oct 21, 1958Daugherty And RockwellAutomatic hypodermic syringe
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3166069 *Feb 14, 1961Jan 19, 1965Astra AbOperating mechanism for automatic hypodermic syringes
US3182660 *Oct 5, 1962May 11, 1965Rudi RonnenbergHypodermic syringe with spring biassed piston
US3217712 *Jan 22, 1963Nov 16, 1965Otto Konigslow Mfg CompanyAmpoule applicator
US3330279 *Oct 18, 1963Jul 11, 1967SarnoffAutomatic hypodermic syringe
US3702609 *Nov 19, 1969Nov 14, 1972Maurice SteinerHypodermic syringes, in particular self-injecting syringes
US3712301 *Jan 11, 1971Jan 23, 1973Survival TechnologyGun type hypodermic injector with rapid cartridge displacement within holder
US3977401 *Mar 25, 1975Aug 31, 1976William Floyd PikeInjection apparatus
US3977402 *Jul 14, 1975Aug 31, 1976William Floyd PikeInjection apparatus and method with automatic aspiration feature
US4031889 *May 19, 1976Jun 28, 1977William Floyd PikePower operated aspirating hypodermic syringe
US4202314 *Nov 20, 1978May 13, 1980Busygin Valery PDevice for injection of medicinal preparations
US4258713 *Jul 23, 1979Mar 31, 1981Wardlaw Stephen CAutomatic disposable hypodermic syringe
US4316463 *Jan 26, 1981Feb 23, 1982Vac-O-Cast, Inc.Corrosive protected hypodermic module
US4767413 *Apr 20, 1987Aug 30, 1988Habley Medical Technology CorporationDental syringe having an automatically retractable needle
US4968302 *Jun 24, 1987Nov 6, 1990Eberhardt SchluterAutomatic injection device, including an ampoule or a cartridge for an injection device
US5114406 *Jan 18, 1990May 19, 1992Wilhelm Haselmeier Gmbh & Co.Injection device for injection, especially self-administered injection, of medicament, including mechanisms for nulling and for selecting dosage, especially for use with multi-dose ampules
US5167632 *Jan 24, 1992Dec 1, 1992New Potency Products, Inc.Syringe
US5354287 *Jan 16, 1991Oct 11, 1994Senetek PlcInjector for delivering fluid to internal target tissue
US5527287 *Dec 7, 1989Jun 18, 1996Miskinyar; Shir A.Preloaded automatic disposable syringe
US5599302 *Jan 9, 1995Feb 4, 1997Medi-Ject CorporationMedical injection system and method, gas spring thereof and launching device using gas spring
US5643211 *Feb 29, 1996Jul 1, 1997Medi-Ject CorporationNozzle assembly having a frangible plunger
US5709668 *Jun 6, 1995Jan 20, 1998Senetek PlcAutomatic medicament injector employing non-coring needle
US5722953 *Feb 29, 1996Mar 3, 1998Medi-Ject CorporationNozzle assembly for injection device
US5800388 *Feb 29, 1996Sep 1, 1998Medi-Ject CorporationPlunger/ram assembly adapted for a fluid injector
US5846233 *Jan 9, 1997Dec 8, 1998Medi-Ject CorporationCoupling device for medical injection system
US5855839 *Apr 29, 1996Jan 5, 1999Sanofi (S.A.)Process for manufacturing an injection device of the pre-filled type containing a dose of liquid for injection and injection device produced
US5865795 *Feb 29, 1996Feb 2, 1999Medi-Ject CorporationSafety mechanism for injection devices
US5875976 *Dec 24, 1996Mar 2, 1999Medi-Ject CorporationLocking mechanism for nozzle assembly
US5891085 *Jan 9, 1997Apr 6, 1999Medi-Ject CorporationNozzle assembly with lost motion connection for medical injector assembly
US5919159 *Jan 9, 1997Jul 6, 1999Medi-Ject CorporationMedical injection system and method, gas spring thereof and launching device using gas spring
US5921967 *Dec 24, 1996Jul 13, 1999Medi-Ject CorporationPlunger for nozzle assembly
US6123684 *Jul 26, 1999Sep 26, 2000Medi-Ject CorporationLoading mechanism for medical injector assembly
US6276567Mar 29, 1999Aug 21, 2001Hydrus, Inc.Pressurized fluid delivery apparatus
US6309371Jul 26, 1999Oct 30, 2001Medi-Jet CorporationInjection-assisting probe for medical injector assembly
US6401975Aug 17, 2001Jun 11, 2002Hydrus, Inc.Pressurized fluid delivery apparatus
US7108675Oct 29, 2001Sep 19, 2006Antares Pharma, Inc.Injection-assisting probe for medical injector assembly
US7637891Sep 12, 2003Dec 29, 2009Children's Hospital Medical CenterMethod and device for painless injection of medication
US7670314Feb 17, 2005Mar 2, 2010Children's Hospital Medical CenterInjection device for administering a vaccine
US7717877 *Jul 28, 2004May 18, 2010Sid Technologies, LlcInjecting apparatus
US7896841Feb 17, 2005Mar 1, 2011Children's Hospital Medical CenterInjection device for administering a vaccine
US8162887Mar 25, 2011Apr 24, 2012Abbott Biotechnology Ltd.Automatic injection devices
US8636704Apr 29, 2010Jan 28, 2014Abbvie Biotechnology LtdAutomatic injection device
US8668670Apr 10, 2012Mar 11, 2014Abbvie Biotechnology LtdAutomatic injection devices
US8679061Mar 5, 2008Mar 25, 2014Abbvie Biotechnology LtdAutomatic injection device
US8708968Jan 24, 2012Apr 29, 2014Abbvie Biotechnology Ltd.Removal of needle shields from syringes and automatic injection devices
US8758301Dec 15, 2010Jun 24, 2014Abbvie Biotechnology LtdFiring button for automatic injection device
EP0633033A2 *Jul 6, 1994Jan 11, 1995Survival Technology, Inc.Rectal administrator
EP0740942A1 *May 2, 1996Nov 6, 1996SanofiProcess of manufacturing a prefilled injection device and injection device produced thereby
WO1986001120A1 *May 29, 1985Feb 27, 1986Survival TechnologyInjection method and apparatus with electrical blood absorbing stimulation
WO1994007553A1 *Sep 30, 1993Apr 14, 1994Senetek PlcMedicament injectors and methods
Classifications
U.S. Classification604/139
International ClassificationA61M5/24, A61M5/28, A61M5/32, A61M5/20
Cooperative ClassificationA61M5/3287, A61M2005/2418, A61M2005/2407, A61M2005/206, A61M2005/2013, A61M5/24, A61M5/2033, A61M5/2459, A61M2005/2488, A61M2005/2086
European ClassificationA61M5/24, A61M5/20C, A61M5/24S2