Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberUS3199489 A
Publication typeGrant
Publication dateAug 10, 1965
Filing dateMar 5, 1964
Priority dateNov 12, 1963
Also published asDE1899499U
Publication numberUS 3199489 A, US 3199489A, US-A-3199489, US3199489 A, US3199489A
InventorsEwlad Wetzel, Friedrich Marx, Hans Luescher, Leo Ruoss
Original AssigneeCiba Ltd
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Container for medicaments
US 3199489 A
Abstract  available in
Images(3)
Previous page
Next page
Claims  available in
Description  (OCR text may contain errors)

Aug. 10, 1965 L. Ruoss ETAL 3,199,489

CONTAINER FOR MEDICAMENTS l Filed Maron 5, 1964 s sheets-sheet 1 I NVE NTOR.

- Aug. 10, 1965 L, Ruoss ETAL 3,199,489

CONTAINER FOR MEDI CAMEN TS Filed March 5, 1964 5 Sheets-Sheet 2 FIG.7

INVENTOR.

Aug. 1o, 1965 Filed March 5, 1964 L. RUOSS ETAL CONTAINER FOR MEDIGAMENTS 5 Sheets-Sheet 3 9 7/ 3Q lz [2 INVENTORS 6o /iuoss United States Patent O 3,1%?,489 CNTAINER FR MEDHCAMENTS Leo Ruoss and Ewald Wetzel, Moehlin, Friedrich Marx, Stein, and Hans Luescher, IBasel, Switzerland, assignors to Ciba Limited, Basel, Switzerland, a company of Switzerland Filed Mar. 5, 1964, Ser. No. 349,705 Claims priority, application Switzerland, Nov. 12, 1963, 13,873/63 2 Claims. (Cl. 116-121) The present invention relates to a container for medicaments for use in human and veterinary medicine which medicaments are in a form ready for administration, for example, pills, tablets, dragees, suppositories, pessaries, and the like, and w-hich have to be administered at speciiied intervals during a determined cycle of treatment. In the container `of the invention the contents are disposed on a disc in one or several concentric circles or spirals, and the container is provided with a dial or spiral strip marked with the prescribed times at which the medicament has to be administered within the cycle of treatment. The marked dial or spiral strip may be either immovable or adjustable, and the position of the contents of the container in relation to the markings of the medicament is due during the cycle of treatment.

ln the novel container of the invention the single doses are disposed in individual compartments arranged in circles or spirals in a section which forms a press out pack-age, which package is formed by superposing a flat covering foil made of a material easy to Itear and suitable for press out tablet extraction on a foil forming a lower section and which is made of a non-rigid but relatively tear-resistant material and of which at least a part is transparent, and attaching it thereto. The lower section is provided with deep indentations arranged in circles or spirals, which indentations, together with the at covering foil, form compartments. The aforementioned circular section forming a press out package is rmly attached to the bottom of the lower part of the container which is made of comparatively rigid material. lt is attached in such a manner that the bottom of the lower part of the container is parallel to the circular section, and the covering toil of the circular section is facing the bottom of the lower part of the container. The bottom of the lower part of the container is provided with apertures corresponding in shape and size of the compartments in the circular package section. They are arranged in circles or spirals and are in register with the compartments. rThus, by applying suitable pressure Ato a compartment, its contents can be removed from the container through an aperture.

In a specially advantageous version of the container of the invention the markings indicating the times of administration are on adjustable dial disposed in the section forming the package which dial is positioned concentrically in relation to the compartments. The dial has a radius shorter than the shortest distance from the centre of any one of the compartments, and the said adjustable dial is provided with a device, for example, a catch mechanism, which enables it to be set permanently and irreversibly in a specilic position selected at the commencement of the treatment cycle.

Material suitable for the covering foil that must be capable or" tearing easily is, for example, paper, cellophane and, more especially, thin aluminum foil.

Non-rigid but tear-resistant material suitable for the lower section is, for example, a toil made of cellulose acetate or polyethylene or polypropylene or more especially plasticized polyvinyl chloride.

The lower part of the container may be made from any comparatively rigid material having adequate mechanical lghid Patented Aug. 10, 1965 `ice strength, for example, aluminum, hardened synthetic resins, for example, phenol resin, urea resin, melamine resin cr epoxy resin, or from suitable thermoplasts, for example, cellulose acetate, polystyrene, polyethylene and the like.

lf desired, lthe lower part of the container may be provided with a lid of conventional type which may be made of the same material .as the lower part of the container or of different material. However, a lid is not essential.

The novel container of the invention is specially suitable for packaging temporary contraceptic preparations. Such a preparation is marketed under the trademark Noracyclin The temporary prevention of conception brought about by such a preparation has nature as its pattern and is based on a physiological principle, namely, the occurrence of infertile phases as a protective function. ln order to ensure that conception is prevented, 1 tablet has to be taken daily from the fth day of the cycle to the twenty-fourth day of the cycle. When medication is discontinued the ovulation cycle recommences and normal fertility is restored. If the tablets are not taken regularly conception can 4occur and pregnancy follows its normal course.

The appended drawings illustrate the invention in greater detail.

FIG. l shows a top view of the container of the inven-` tion, intended for a contraceptive, without lid.

FlG. 2 -shows a cross-section of the container through the line 2 2 in FIG. l with the dial in position.

FIG. 3 shows a top view of the package section of the container depicted in FIG. l.

FlG. 4 shows a cross-section of the package section of the container through the line i-fi in FIG. 3.

FlG. 5 shows a top view of the lower part of the container depicted in FIG. 1 with the dial removed.

FIG. 6 shows a cross section of the lower part of the container through the line 6 6 lin FIG. 5.

PlG. 7 shows a perspective view of the container of the invention with lid partly broken-away.

FIG. S shows an exploded perspective view of the container of the invention.

FIG. 9 shows a cross-sectional view of the container of the invention showing the relationship of the various parts.

In the drawings, the package section 1 is made up of a lower section 2 made of plasticized polyvinyl chloride and is provided with a total of 20 ldeep indentations 3 for the contraceptive tablets 4, which indentations are arranged in two concentric circles, and a covering foil 5 made of aluminum. The package section 1 is provided with peripheral notches d, a central aperture 7, and concentrically arranged apertures S.

The package section 1 is rigidly attached to the lower part of the container 9, which is made of polyethylene. The cam 1t) prevents movement in a vertical direction, and `the studs 11 engage the peripheral notches 6 to prevent circular movement. The lower par-t of the container 9 is provided with a total of 2O apertures 12 arranged in two concentric circles, which apertures correspond exactly in number, shape and position to the concentrically arranged compartments 3 of .the package section 1, and which are in exact register with the said compartments 3.

rl`he lower part of the container 9 is furthermore provided with a central boss 13, which has an undercut 13a, and also concentrically arrange-d studs 14. The boss 13 and the studs 14 engage the apertures '7 and ofthe package section. A dial i5 with concentrically arranged holes 16 is disposed on the central boss 13. Before the container is used, the di-al 15 rests on the undercut 13a and can be turned round on the boss 13. The dial is inscribed with the days of the week arranged radially at regular intervals. The inscriptions are spaced in such a adsense manner lthat the 2() tablet compartments 3 of the package section lie on the radial extensions of the inscriptions of 20 successive days when a specific day is set in position at the red mark M. The day then pointing to the first compartment is always the fifth day, inclusive, from the day at the red mark.

The container lis used as follows: On the first day of the cycle, that .is to say, the day that menstrual bleeding commences, for example, a Tuesday, the dial is turned until the word Tuesday is in line with the red mark M. The day on which the treatment is to commence, namely, the following Saturday, is then automatically in position opposite the first tablet compartment (counting clockwise). The dial is then pressed down below lthe undercut 13a and the concentrically arranged studs 14 of the lower part of the container engage the holes 16 in the dial and lock -it in position. It is then possible to see on which days a tablet has to be taken. The tablets are extracted from the container by pressing the compartments 3 through the apertures 12 in the lower part of the container; the aluminium `covering foil 5 tears and the tablet drops out. 1f the person undergoing treatment forgets to take a tablet the over-sight can be detected by the tact that the cornpartment for that particular day is still intact. Reliable control is thus possible.

The lower part of the container may be covered by a removable lid 117 made of opaque material, for example, polyethylene.

The tablets in the transparent package section are thus protected from the action of light.

The invention is not restricted to the version described above. Tn particular, `the adjustable dial may be replaced by an immovable circular plate inscribed with numbers. The igure 1 represents the first day of the cycle and is in the same position as the red mark M in the preceding version. The figure 5, corresponding .to the fifth day of the cycle, is then `opposite the first compartment (counting clockwise), the figure 6, corresponding to the sixth day of the cycle, is opposite the second compartment, and so forth, up to the figure 24 representing the 24th day of the cycle which is opposite the last compartment.

The drawback to this version as compared with the first system described is that 1a calendar check has to be carried out throughout the period of treatment.

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:

l.. A dispenser for a medicament to be administered at specific intervals, which medicament is in the form of pills and the like, comprising a walled container having a rigid base, said base formed with a plurality of concentrically arranged openings, of size suficiently large to permit press out of said medicament, an easily tearable foil, completely covering said base7 extending to the periphery of said baise, a central shaft attached to said base, a removably movable dial of radius less than that of said concentrically arranged openings mounted on said shaft, means on said base cooperating with means on said dial for locking said dial, a scale on said foil concentric with and positioned adjacent to the periphery of said dial, each unit of said medicament being positioned on said easily-tearable foil, a non-rigid tear-resistant foil for encapsulating said medicament positioned in `said container, whereby said medicament is maintained in registry with said concentrically arranged openings to permit press out egress through said openings.

2. A dispenser for a medicament to be administered at specific intervals, which medicament is in the form of pills and the like, comprising a walled container having a rigid base, said base formed with a plurality of spirally arranged openings7 of size suiliciently large to permit press out of said medicament, an easily-tearable foil, completely covering said base, extending to the periphery of said base, a central shaft attached to said base, a removably movable dial of radius .less Ithan that of said spirally arranged openings mounted on said shaft, means on said base cooperating with means on said dial for locking said dial, a scale on said foil concentric with .and positioned adjacent to the periphery of said dial, each unit of said medicament being positioned on said easilyatearable foil, a non-rigid tear resistant foil for encapsulating said medicament positioned within said container, whereby said medicament is maintained in registry with said concentrically arranged openings to permit press out egress through said openings.

Referenees Cited by the Examiner UNITED STATES PATENTS 1,240,026 9/ 17 Chapman 206-42 2,164,719 7 39 Peterson et al 206-42 2,317,860 4/43 Sorensen 206-42 2,328,119 8/43 Allen 206-78 2,3 86,416 10/ 45 Wilhelm 206-42 2,953,242 9/ 60 Shaw 206-42 2,971,638 2/61 Allison et al 206-78 l3,085,679 4/ 63 Burrell 206-42 3,124,241 3/ 64 Holley et al. 206-78 3,143,207 8/64 Wagner 206-42 FOREIGN PATENTS 712,676 7/31 France.

LOUIS CAPOZI, Primary Examiner.

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US1240026 *Oct 10, 1912Sep 11, 1917Everett Brown ChapmanSurgical appliance.
US2164719 *Jan 15, 1938Jul 4, 1939Shoup Owens IncContainer for pills, capsules, and the like
US2317860 *Jun 25, 1940Apr 27, 1943Emil SorensenDisplay tablet container
US2328119 *Sep 26, 1940Aug 31, 1943Paul E AllenDisplay container
US2386416 *Mar 1, 1943Oct 9, 1945Wilhelm Warren FTablet and means for packaging same
US2953242 *Jul 31, 1957Sep 20, 1960Gustave MillerContainer and time indicator
US2971638 *May 24, 1956Feb 14, 1961Sparks CorpDispensing containers
US3085679 *Oct 17, 1960Apr 16, 1963American Hospital Supply CorpDispenser
US3124241 *Mar 21, 1960Mar 10, 1964HOIIEY Plastics CompanyFigure
US3143207 *Jul 27, 1962Aug 4, 1964David P WagnerMedication dispensing means
FR712676A * Title not available
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3270915 *Feb 3, 1965Sep 6, 1966Searle & CoDispensing means for pharmaceutical tablets
US3276573 *Jan 21, 1965Oct 4, 1966Searle & CoDispensing device for solid-form pharmaceutical preparations
US3279651 *Feb 8, 1965Oct 18, 1966Thompson Gordon JArticle dispenser having rupturable cells and means to eject articles therefrom
US3288277 *Sep 22, 1965Nov 29, 1966Richardson Merrell IncDispensing container
US3302775 *Apr 13, 1965Feb 7, 1967Sparks CorpReminder-dispenser device
US3324996 *Jan 19, 1966Jun 13, 1967Searle & CoDispenser for pharmaceutical tablets
US3397671 *Mar 22, 1965Aug 20, 1968Sparks CorpReminder-dispenser device
US3454152 *Dec 19, 1967Jul 8, 1969Lilly Co EliPill dispenser with indicating means
US4053054 *Oct 7, 1975Oct 11, 1977Padeg A.G.Package having individual isolated cells
US4124143 *Feb 11, 1977Nov 7, 1978Ryder International CorporationPill dispenser
US4165709 *Jan 24, 1978Aug 28, 1979Ortho Pharmaceutical CorporationTablet dispenser
US4298125 *May 19, 1980Nov 3, 1981Bristol-Myers CompanyDial type child resistant dispenser
US4646936 *Jun 21, 1985Mar 3, 1987Ortho Pharmaceutical CorporationPill dispenser
US4706815 *Aug 23, 1982Nov 17, 1987American Home Products CorporationDispensing container for triphasic
US5019125 *Jun 26, 1990May 28, 1991Marion Merrell Dow Inc.Dispensing container
US5109984 *Jun 22, 1990May 5, 1992Romick Jerome MUnit-dose medication handling and dispensing system
US5110007 *Sep 5, 1989May 5, 1992Imperial Chemical Industries PlcDispenser
US5348158 *Dec 19, 1991Sep 20, 1994G. D. Searle & Co.Dispenser pack for the successive dispensing of a drug
US5368187 *Jan 19, 1993Nov 29, 1994Poncetta; StanleyMethod and apparatus for dispensing materials from blister packages
US5551597 *Jun 6, 1995Sep 3, 1996Ortho Pharmaceutical CorporationVariable day start tablet dispenser
US5562231 *Jul 29, 1994Oct 8, 1996Ortho Pharmaceutical CorporationVariable day start tablet dispenser
US5570810 *Jun 6, 1995Nov 5, 1996Ortho Pharmaceutical CorporationVariable day start tablet dispenser
US5775536 *May 14, 1996Jul 7, 1998Ortho Pharmaceutical Corp.For dispensing a regimen of pills in a designated sequence
US5799821 *Jun 19, 1996Sep 1, 1998Ortho Pharmaceutical CorporationVariable day start tablet dispenser
US6039208 *Mar 16, 1998Mar 21, 2000Ortho Pharmaceutical CorporationVariable day start tablet dispenser
US7588149 *Apr 21, 2005Sep 15, 2009Meadwestvaco CorporationUnit dose container with locking sleeve
US8579116 *Mar 26, 2012Nov 12, 2013Oneworld Design and Manufacturing Group, Ltd.Tamper evident device
US20110259781 *Sep 10, 2009Oct 27, 2011Boehringer Ingelheim International GmbhPackaging unit
US20120241451 *Mar 26, 2012Sep 27, 2012Fred PetherTamper Device
US20120292225 *May 18, 2012Nov 22, 2012Berry Plastics CorporationTablet package
DE4230509C1 *Sep 11, 1992Apr 14, 1994Fraunhofer Ges ForschungBehälter zur Aufnahme von ringförmigen Trägern für zyklisch anzuwendende Arzneimittel
DE19813350A1 *Mar 26, 1998Sep 30, 1999Bayer AgPressing device for the removal of tablets from a blister pack
WO1994006398A1 *Sep 8, 1993Mar 31, 1994Fraunhofer Ges ForschungContainer for supports for medicaments to be used cyclically
Classifications
U.S. Classification116/308, 206/538, 206/531, 206/534
International ClassificationB65D83/04, A61J1/00, B65D85/16, A61J7/04
Cooperative ClassificationB65D2583/0409, B65D83/0463, A61J7/04, B65D85/16
European ClassificationB65D83/04C2, B65D85/16