|Publication number||US3301258 A|
|Publication date||Jan 31, 1967|
|Filing date||Oct 3, 1963|
|Priority date||Oct 3, 1963|
|Publication number||US 3301258 A, US 3301258A, US-A-3301258, US3301258 A, US3301258A|
|Inventors||George Werner, Wingrove Robert C|
|Original Assignee||Medtronic Inc|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (2), Referenced by (86), Classifications (12)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Jan. 31, 1967 A G. WERNER ETAL METHOD AND APPARATUS FOR TREATING VARICOSE VEINS 2 Sheets-Sheet 1 Filed Oct. 5, 1963 g m u M r H H UHIH m M W m y TM h Q |.l| :l WM A a m. A z r1 .iiill W I.]ib|,|i: 1 il M k HQ 9 M W n a W \m or MN w W w J M lWllWH l' fi A Mm l m av l V Q mm W HUN m United States Patent Ofifice 133M258 Patented Jan. 31, 1967 3,301,258 METHOD AND APPARATUS FQR TREATING VARICOSE VEINS George Werner, Minneapolis, and Robert C. Wingrove, New Brighton, Minn, assignors to Medtronic, Inc., Minneapolis, Minn, a corporation of Minnesota Filed Oct. 3, 1963, Ser. No. 313,597 6 Claims. (Cl. 128303.1)
This invention has relation to a method for treating varicose veins and to apparatus for performing that method.
In the method of the invention the veins are destroyed rather than removed. The destroyed veins are then consumed and absorbed by normal body process. This vein destruction is accomplished by application of intense localized heat applied through the instrumentality of a probe forced through the fatty subcutaneous tissue between the fascia and the skin. Two electrodes forming an outer end of the probe are spaced from and insulated from each other and an electric current is passed between them while they are in adjacent relationship to a portion of a vein to be destroyed. The duration of such current flow is brief and the amount of heat energy released by passage of such current is closely controlled.
This precisely located intense localized precisely controlled amount of heat energy destroys the vein but does not do permanent damage to the adjacent muscle or its covering fascia, does not permanently harm adjacent nerves and does not burn through to the skin. Instead the function of the nearby superficial sensory nerves is temporarily impaired and consequently no pain sensations from them are experienced by the patient during the healing process and some numbness is sometimes experienced by the patient during the postoperative healing process. However, as the tissue which has been heated heals, so do these nerves. As these nerves heal, they renew their function, so that full sensation is restored as healing is completed.
Varicose veins are enlarged twisted veins and are most commonly found on the lower leg and thigh. They sometimes occur following pregnancy, in persons whose occupations require standing positions, in the obese, and in persons having cogenitally defective venous valves.
The recognized proper treatment for this condition before the present invention has been to strip the dilated veins from the patient. The greater and short saphenous veins are usually straight tubes and can be easily removed using intraluminal strippers. However, the tortuous veins, the large venous plexuses, the veins in the anterior, lateral, and posterior thigh and calf do not permit the passage of strippers. Under procedures prevailing before the invention, these veins were removed by dissection through multiple incisions. This was and is tedious surgery and is often omitted or done inadequately. If such surgery is done thoroughly, the patient may be left with many incisional scars. If all these varicose veins are not removed, the patient has a persistence of the varicose vein condition.
While this stripping and excision procedure is the most successful operation to the date of this invention, and was the prevailing method of treating varicose veins, both doctors and patients have not been completely satisfied with it. The cosmetic damage occasioned by multiple disfiguring scars, and the persistence and recurrence of varicose veins where the surgery is not done thoroughly, and the intense and lingering pain associated with the operation and particularly with the recovery period have been factors contributing to the dissatisfaction of patients with the operation. For the surgeon, the operation can be long, arduous and tedious, and can sometimes actually tax or exceed the physical stamina of the surgeon.
It is an object of the method of the present invention and of the apparatus for performing that method to largely overcome these difficulties.
In the drawings, FIG. 1 is a side elevational view of a surgical instrument made according to the present invention showing its relationship to a patients leg when used to destroy varicose veins in the lower leg;
FIG. 2 is a side elevational view of said instrument shown in position to destroy varicose veins in the thigh of a patient;
FIG. 3 is an enlarged side elevational view of the instrument;
FIG. 4 is a greatly enlarged transverse sectional view of an outer end of a probe of the instrument of the invention;
FIG. 5 is a block diagram of electrical components of apparatus of the invention; and
FIG. 6 is one useful form of circuit diagram of the components illustrated in FIG. 5.
Referring to the drawings and the numerals of reference thereon, an elongated probe 8 forms part of a surgical instrument referred to herein as probe assembly 9. The probe 8, as shown, includes a hollow cylindrical metallic tube 10 which forms a first electrode of the probe assembly. This first electrode 10 extends outwardly from an insulating handle 11 of the probe assembly, and an outer end of this first electrode fixedly receives a hollow tubular insulator 13 as at 14. This insulator 13 fixedly receives, as at 16, a metallic, hollow tip 15 which forms a second electrode of the probe assembly 9. An outer, generally conical, portion of the second electrode 15 is designated 17.
In addition to the probe assembly 9, the electrical components of the apparatus of the invention includes an oscillator 12, a timer 24 and an electrical power source 26. The power source is connected to the oscillator through the instrumentality of wires 28 and 29. The timer 24 is connected to the oscillator through the in strumentality of wires 19 and 25. The output from the oscillator 12 is fed along a common wire 18 to an electrical contact with the first electrode 10 as at 36. The output from the oscillator is also fed through a wire 20 which extends throughout the length of the electrode 10 in spaced, insulated relationship therefrom and is elec trically connected to the second electrode 15 as at 37 (see FIG. 4).
Common wire 18 also extends to the timer 24 and to one terminal of a switch 22 which is included in a switch case 21 mounted on handle 11 to form part of the probe assembly 9. The second terminal of the switch 22 is con nected through a wire 23 to the timer 24. As best seen in FIG. 3, these wires 18, 2t) and 23 leave the handle 11 of "the probe assembly 9 as part of the cable 30 which terminates in a plug 27. These wires extend outwardly from the plug in the form of banana-type connections. Obviously the oscillator 12 and the timer 24 can be mounted in a single case and the power supply to that case and the power supply to that case can come from any desired location such as a commercial power outlet. It is to be noted that the probe assembly 9, including the switch 22 and the switch case 21 as well as the probe 8 and its insulator 13 and electrodes 10 and 15, is a surgical instrument and as such is constructed so that it can be sterilized in an autoclave or by other known procedures. This, of course, is an imporatnt feature inasmuch as the instrument is used in surgery and, therefore, must be sterile.-
The particular circuitry to be effective in performing the method of the invention can take any one of several forms; but a circuit which is particularly useful in performing the method of the invention is illustrated in FIG. 6.
In order to obtain the intense, highly localized, precisely controlled amount of heat energy at the precisely located point to effectively destroy adjacent varicose veins, it has been found satisfactory to utilize an oscillator which generates alternating current at the rate of 500 kilocycles per second. The circuitry is such that closing of the switch 22 by the surgeon will trigger the timer to introduce the output of the oscillator at about 200 volts between the first electrode and the second electrode for one-half of a second. While these values have been found to be the most satisfactory to date, it is to be understood that certain variations can be made within the spirit of the invention and the scope of the claims which follow. For example, in the anterior tibial area and behind the knee, the extreme thinness of the fatty subcutaneous layer increases the chance of burns through to the skin. In these areas, the frequency of the oscillator can be increased and the amplitude or duration of the impulse can be decreased. This can result in the release of the same amount of heat energy between the electrodes but the penetration of this heat will be restricted to even closer proximity to the surface of the insulator 13, thus reducing the possibility of burning through the skin but still effectively destroying the adjacent veins.
Technique The following technique has been found to be satisfactory for the performance of the method of the invention. Variation in this technique and even changes of technique will be possible within the spirit of the invention and the scope of the claims.
The patient is admitted to the hospital one day prior to surgery. On this day, every varicose vein on the patients legs is carefully mapped out with indelible ink. In order to accomplish this careful marking, the patient stands on a stool in good light, and all varicose veins including small early varicose veins and large venous plexuses are carefully outlined. Perforators are identified and marked.
At surgery, a saphenous ligitation is done in a usual manner. The long saphenous vein, which is indicated as partially outlined on the patients leg 32 at 40 in FIGS. 1 and 2, is picked up on the ankle or foot through a small incision 35 (see FIG. 2), and stripped to an inguinal incision (not shown). This can usually be done with one stripper. In cases where an additional incision is necessary, an incision 31 on the inner leg at the knee is utilized.
Whether or not this incision is necessary to strip the long or greater saphenous vein 40, this incision 31 is utilized throughout the remainder of the operation as the site of the entrance of the probe 8 of the probe assembly 9. This incision is a small stab incision made with a number 11 Bard-Parker blade. The probe 8 of the probe assembly 9 is forced through the subcutaneous layer under the skin to posit-ion under the indelible marking on the skin which represent the positioning of the varicose veins to be destroyed. Using these skin markings, the electrodes 10 and 15 at the outer end of the probe 8 are placed as close as possible to the vein. In doing this, the surgeon takes into consideration the fact that the current flow and hence the heat generated will be along the periphery of the insulator 13 between the electrodes 10 and 15. The current will flow to and from the electrode 10 approximately at the circular line 38 around the probe. The current will flow to and from the electrode 15 approximately at the circular line 39. Thus the area of generated heat will be cylindrical in shape and will extend between the lines 38 and 39. The positioning of the probe may be under, over, alongside or through the vein. However, no effort is made to pass the probe down the lumen of the vein.
When the probe is properly positioned with respect to a portion of a vein to be destroyed, the switch 22 on handle 11 is touched by the surgeon, and a current flow to and from electrodes 10 and 15. This flow causes an intense heat to be generated in the tissue through which it passes. Any vein adjacent the insulator 13 and in the area of this current flow will be effectively destroyed. The probe is then advanced or withdrawn a distance approximately equal to the length of the insulator 13 or to other position where it will be in immediate adjacent relationship to the next length of vein to be destroyed. When so positioned, the switch is again activated to heat the adjacent tissue and vein. The process is continued until all areas of tortuous veins are destroyed. As shown, the probe is approximately fifteen inches long and it can be passed long distances under the skin to destroy the veins.
In FIG. 1, the probe is shown as entering the leg 32 through the incision 31 to extend into the lower leg 34 and to destroy veins therein. Should it be necessary or desirable to destroy varicose veins in the thigh 33, the probe 8 will be inserted through the incision 31 as shown in FIG. 2. The probe can be inserted either up or down the leg as many times as necessary to reach all veins to be destroyed.
Veins which have perforated through the fascia are known as perforat-ors and are destroyed by pointing the probe down near the fascia in adjacent relationship to the afflicted vein. An increase in the length of the electrical impulse will often be advantageous in destroying such veins.
Throughout this fulguration period, the patient is kept in slight Trendelenb-urg position. This tends to empty the varicose veins of blood.
If the patient has incompetent, short, saphenous veins, these are stripped, as was the greater saphenous vein, in the conventional manner.
Upon completion of surgery, the legs are wrapped tightly with elastoplast. The foot of the bed is elevated, and the patients are encouraged to walk the evening of the day of surgery.
Postoperatively the only pain is in the inguinal incisions. As previously pointed out, lack of other pain is due to the anesthesia growing out of temporary impairment of the function of the sensory nerves adjacent the site of the electrodes of the probe. Part of the reason for the lack of pain during healing of the incisions 31 and 35 is the temporary impairment of the function of the nerves normally serving those areas due to application of heat to these nerves at other positions along the leg.
The inguinal incisions are made in the usual manner, and are closed in the usual manner. Thus the usual pain which accompanies healing of any such incision is to be expected. However, the incision 31 through which the probe is inserted is small enough so that no stitches are required. Typically the length of the incision will be about 3 inch. The incision is closed with an adhesive bandage such as a Band-Aid. When this incision has healed, it will be, to all intents and purposes, invisible. The same can be said about the incision 35 and near the foot or ankle.
Because of the virtual invisibility of these lower incisions, the cosmetic aspects of the method of the invention are perfect. Consequently, models and other persons who cannot or will not have scar tissue on their legs are now candidates for this surgery, and such surgery has been performed on such patients with completely successful results from the cosmetic standpoint as well as other standpoints. Not only are there no scars as a result of the operation, but, after the destroyed veins have been absorbed and consumed by the normal processes of the body, the disappearance of the unsightly veins themselves enhances the appearance of the patients legs.
Because the present operation consists only of passing the probe a number of times through the incision 31 to the site of the veins to be destroyed and of then passing current between the electrodes in the probe, the operation takes a much shorter time than formerly. Also, the operation by the method of the present invention is much more thoroughly performed as even the smallest of veins can be quickly destroyed without the necessity of separate incisions at the site of each such small vein.
What is claimed is:
1. The method of treating varicose veins including the steps of: making an incision through the cutaneous layer, inserting a probe into the incision and along the tissue of the subcutaneous layer to the site of a section of vari- COSe vein to be treated, and passing an electric current through said tissue adjacent said section of vein between two electrodes of said probe, said current being such as to generate sufiicient heat in said vein section to destroy said section.
2. The method as specified in claim 1 and the additional steps of: successively moving said probe to other sites of sections of varicose veins to be treated and passing an electric current through tissue adjacent each such site to destroy said vein sections.
3. The method of treating varicose veins in th legs of a patient including the steps of:
(a) causing the patient to stand;
(b) restricting the circulation in the legs of the patient to cause the veins to protrude;
(c) then indelibly tracing the pattern of the varicose veins in the patients legs;
(d) preparing the patient for operative procedures;
(e) stripping varicose saphenous veins from the legs;
(f) placing the patient in a slight Trendelenburg position;
(g) making an incision through the cutaneous layer on the inside of the knee;
(h) inserting a probe into the incision and along the tissue of the subcutaneous layer to the site of a section of varicose vein to be treated;
(i) passing a high frequency electric current through said tissue adjacent said section of vein between two electrodes of said probe, said current being such as to generate sufiicient heat in said vein section to destroy said section; and
(j) successively moving said probe to other sites of sections of varicose veins to be destroyed and passing a high frequency electric current through tissue adjacent each such site to destroy said vein sections.
4. Apparatus for treating varicose veins in an animate body including a slender cylindrical probe of a diameter to pass through an incision in the skin and along the subcutaneous layer of an animate body between the fascia and the skin, said probe having a first hollow cylindrical electrode, a cylindrical insulator concentric with, of the same diameter as, and extending forwardly from said first electrode, a second cylindrical electrode concentric with, of the same diameter as, and extending forwardly from said insulator; a first electrical connection extending the length of said probe through said first electrode in insulated relation thereto, through said insulator and into electrical contact with said second electrode; means for generating high frequency electrical energy; and circuit means for connecting the output of said generating means between said first electrode and said first electrical connection.
5. The combination as specified in claim 4, switch means for activating said generator means, and a timer operative upon actuation of said switch means for deactivating said generator means after a predetermined time interval.
6. The combination as specified in claim 4, switch means operative to activate said generator means, and metering means for effectively interrupting connection between said generating means and said electrodes when a predetermined amount of heat energy has been released between said electrodes.
References Cited by the Examiner M. Politowski et al.: Varices of the lower extremities treated by electrocoagulation. In Surgery, vol. 56, No. 2, August 1964, pages 355-360.
ROBERT E. MORGAN, Acting Primary Examiner.
RICHARD A. GAUDET, Examiner.
G. MCNEILL, Assistant Examiner.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2764928 *||Dec 28, 1954||Oct 2, 1956||Martinson Marvin P||Automobile ventilator|
|US2888928 *||Apr 15, 1957||Jun 2, 1959||Wright Seiger Harry||Coagulating surgical instrument|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3618600 *||Apr 1, 1969||Nov 9, 1971||Douglass Harry E||Ear stopple|
|US3698394 *||Jun 14, 1971||Oct 17, 1972||Polak Teodor||Electrically heated hypodermic needle|
|US3886944 *||Nov 19, 1973||Jun 3, 1975||Jamshidi Khosrow||Microcautery device|
|US4654024 *||Sep 4, 1985||Mar 31, 1987||C.R. Bard, Inc.||Thermorecanalization catheter and method for use|
|US4682596 *||May 22, 1984||Jul 28, 1987||Cordis Corporation||Electrosurgical catheter and method for vascular applications|
|US5507744 *||Apr 30, 1993||Apr 16, 1996||Scimed Life Systems, Inc.||Apparatus and method for sealing vascular punctures|
|US5810810 *||Jun 6, 1995||Sep 22, 1998||Scimed Life Systems, Inc.||Apparatus and method for sealing vascular punctures|
|US5868744 *||Apr 28, 1995||Feb 9, 1999||Willmen; Hans-Rainer||Electrosurgical instrument for therapeutic treatment of varices|
|US6014589 *||Nov 12, 1997||Jan 11, 2000||Vnus Medical Technologies, Inc.||Catheter having expandable electrodes and adjustable stent|
|US6033397 *||Sep 26, 1996||Mar 7, 2000||Vnus Medical Technologies, Inc.||Method and apparatus for treating esophageal varices|
|US6033398 *||Mar 4, 1997||Mar 7, 2000||Vnus Medical Technologies, Inc.||Method and apparatus for treating venous insufficiency using directionally applied energy|
|US6036687 *||Mar 5, 1996||Mar 14, 2000||Vnus Medical Technologies, Inc.||Method and apparatus for treating venous insufficiency|
|US6063085 *||Oct 22, 1993||May 16, 2000||Scimed Life Systems, Inc.||Apparatus and method for sealing vascular punctures|
|US6071277 *||Jul 1, 1997||Jun 6, 2000||Vnus Medical Technologies, Inc.||Method and apparatus for reducing the size of a hollow anatomical structure|
|US6135997 *||Nov 16, 1998||Oct 24, 2000||Vnus Medical Technologies, Inc.||Method for treating hemorrhoids|
|US6139527 *||Sep 26, 1996||Oct 31, 2000||Vnus Medical Technologies, Inc.||Method and apparatus for treating hemorrhoids|
|US6152899 *||Jul 17, 1997||Nov 28, 2000||Vnus Medical Technologies, Inc.||Expandable catheter having improved electrode design, and method for applying energy|
|US6165172 *||Oct 26, 1997||Dec 26, 2000||Vnus Medical Technologies, Inc.||Expandable vein ligator catheter and method of use|
|US6179832||Aug 21, 1998||Jan 30, 2001||Vnus Medical Technologies, Inc.||Expandable catheter having two sets of electrodes|
|US6200312||Sep 11, 1997||Mar 13, 2001||Vnus Medical Technologies, Inc.||Expandable vein ligator catheter having multiple electrode leads|
|US6228082 *||Dec 3, 1998||May 8, 2001||Arthrocare Corporation||Systems and methods for electrosurgical treatment of vascular disorders|
|US6231507||Jun 2, 1997||May 15, 2001||Vnus Medical Technologies, Inc.||Pressure tourniquet with ultrasound window and method of use|
|US6237606||Mar 10, 1999||May 29, 2001||Vnus Medical Technologies, Inc.||Method of applying energy to tissue with expandable ligator catheter having multiple electrode leads|
|US6258084||Mar 10, 1999||Jul 10, 2001||Vnus Medical Technologies, Inc.||Method for applying energy to biological tissue including the use of tumescent tissue compression|
|US6263248||Sep 10, 1999||Jul 17, 2001||Vnus Medical Technologies, Inc.||Catheter having expandable electrodes and adjustable stent|
|US6267758 *||Jan 28, 1997||Jul 31, 2001||Esc Medical Systems Ltd.||Apparatus for in situ saphenous vein bypass and less-invasive varicose vein treatment|
|US6293944 *||Sep 10, 1999||Sep 25, 2001||Alan G. Ellman||Combined syringe and electrosurgical electrode for sclerotherapy|
|US6322559||Jul 6, 1998||Nov 27, 2001||Vnus Medical Technologies, Inc.||Electrode catheter having coil structure|
|US6361496||May 28, 1999||Mar 26, 2002||Vnus Medical Technologies, Inc.||Pressure tourniquet with ultrasound window and method of use|
|US6398780||Feb 3, 2000||Jun 4, 2002||Vnus Medical Technologies, Inc.||Expandable vein ligator catheter and method of use|
|US6398782 *||May 15, 1995||Jun 4, 2002||Edwards Lifesciences Corporation||Bipolar vascular sealing apparatus and methods|
|US6401719||Aug 21, 1998||Jun 11, 2002||Vnus Medical Technologies, Inc.||Method of ligating hollow anatomical structures|
|US6613045||Feb 1, 2000||Sep 2, 2003||Vnus Medical Technologies, Inc.||Method and apparatus for treating venous insufficiency|
|US6638273||Nov 27, 2000||Oct 28, 2003||Vnus Medical Technologies, Inc.||Expandable catheter having improved electrode design, and method for applying energy|
|US6682526||Nov 17, 2000||Jan 27, 2004||Vnus Medical Technologies, Inc.||Expandable catheter having two sets of electrodes, and method of use|
|US6689126||Feb 3, 2000||Feb 10, 2004||Vnus Medical Technologies, Inc.||Expandable vein ligator catheter and method of use|
|US6752803||Jul 6, 2001||Jun 22, 2004||Vnus Medical Technologies, Inc.||Method and apparatus for applying energy to biological tissue including the use of tumescent tissue compression|
|US6769433||May 25, 2001||Aug 3, 2004||Vnus Medical Technologies, Inc.||Expandable vein ligator catheter having multiple electrode leads, and method|
|US6969388||Apr 23, 2001||Nov 29, 2005||Vnus Medical Technologies, Inc.||Apparatus for applying energy to biological tissue including the use of tumescent tissue compression|
|US6981972||Jan 18, 2000||Jan 3, 2006||Vnus Medical Technologies, Inc.||Apparatus for treating venous insufficiency using directionally applied energy|
|US7041098||Jun 3, 2002||May 9, 2006||Vnus Medical Technologies, Inc.||Expandable vein ligator catheter and method of use|
|US7396355||Jun 21, 2004||Jul 8, 2008||Vnus Medical Technologies, Inc.||Method and apparatus for applying energy to biological tissue including the use of tumescent tissue compression|
|US7406970||Jul 28, 2004||Aug 5, 2008||Vnus Medical Technologies, Inc.||Method of using expandable vein ligator catheter having multiple electrode leads|
|US7468059||Feb 9, 2007||Dec 23, 2008||Arthrocare Corporation||System and method for epidermal tissue ablation|
|US7625372||Aug 5, 2005||Dec 1, 2009||Vnus Medical Technologies, Inc.||Methods and apparatus for coagulating and/or constricting hollow anatomical structures|
|US7641633||Mar 25, 2003||Jan 5, 2010||Tyco Healthcare Group, Lp||Apparatus for treating venous insufficiency|
|US7758537||Apr 16, 1999||Jul 20, 2010||Arthrocare Corporation||Systems and methods for electrosurgical removal of the stratum corneum|
|US7824408||Aug 5, 2004||Nov 2, 2010||Tyco Healthcare Group, Lp||Methods and apparatus for coagulating and/or constricting hollow anatomical structures|
|US7828793||Jan 21, 2010||Nov 9, 2010||Tyco Healthcare Group, Lp||Methods for treating a hollow anatomical structure|
|US7837677||Jan 12, 2010||Nov 23, 2010||Tyco Healthcare Group, Lp||Systems for treating a hollow anatomical structure|
|US7837678||Feb 24, 2010||Nov 23, 2010||Tyco Healthcare Group, Lp||Systems for treating a hollow anatomical structure|
|US7901402||May 23, 2008||Mar 8, 2011||Tyco Healthcare Group, Lp||Expandable catheter having two sets of electrodes|
|US7963961||Oct 25, 2010||Jun 21, 2011||Tyco Healthcare Group Lp||Systems for treating a hollow anatomical structure|
|US7963962||Nov 9, 2010||Jun 21, 2011||Tyco Healthcare Group Lp||Methods for treating a hollow anatomical structure|
|US7976536||Nov 16, 2005||Jul 12, 2011||Tyco Healthcare Group Lp||Method and apparatus for treating venous insufficiency|
|US8043285||Nov 19, 2010||Oct 25, 2011||Tyco Healthcare Group Lp||Systems for treating a hollow anatomical structure|
|US8083738||Nov 1, 2010||Dec 27, 2011||Tyco Healthcare Group Lp||Method and apparatus for coagulating and/or constricting hollow anatomical structures|
|US8291915||Apr 27, 2011||Oct 23, 2012||Tyco Healthcare Group Lp||Method and apparatus for treating venous insufficiency using directionally applied energy|
|US8321019||Jul 21, 2006||Nov 27, 2012||Covidien Lp||Apparatus and method for ensuring safe operation of a thermal treatment catheter|
|US8357157||Dec 7, 2011||Jan 22, 2013||Covidien Lp||Methods and apparatus for coagulating and/or constricting hollow anatomical structures|
|US8361061 *||Nov 25, 2009||Jan 29, 2013||Covidien Lp||Methods and apparatus for coagulating and/or constricting hollow anatomical structures|
|US8366706||Aug 15, 2008||Feb 5, 2013||Cardiodex, Ltd.||Systems and methods for puncture closure|
|US8372072||Nov 22, 2011||Feb 12, 2013||Cardiodex Ltd.||Methods and apparatus for hemostasis following arterial catheterization|
|US8435235||Apr 25, 2008||May 7, 2013||Covidien Lp||Systems and methods for treating hollow anatomical structures|
|US8435236 *||Nov 21, 2005||May 7, 2013||Cardiodex, Ltd.||Techniques for heat-treating varicose veins|
|US8636729||Jul 21, 2006||Jan 28, 2014||Covidien Lp||Therapeutic system with energy application device and programmed power delivery|
|US8679110||Jul 28, 2008||Mar 25, 2014||Covidien Lp||Expandable vein ligator catheter having multiple electrode leads, and method|
|US8721634||Jul 21, 2006||May 13, 2014||Covidien Lp||Apparatus and method for ensuring thermal treatment of a hollow anatomical structure|
|US8721639||Dec 21, 2012||May 13, 2014||Covidien Lp||Methods and apparatus for coagulating and/or constricting hollow anatomical structures|
|US8795266 *||Dec 21, 2012||Aug 5, 2014||Covidien Lp||Methods and apparatus for coagulating and/or constricting hollow anatomical structures|
|US8849395||May 30, 2008||Sep 30, 2014||Boston Scientific Scimed, Inc.||Guide catheter having vasomodulating electrodes|
|US8852178||Sep 12, 2011||Oct 7, 2014||Covidien Lp||Systems for treating a hollow anatomical structure|
|US8936631||Aug 20, 2010||Jan 20, 2015||Covidien Lp||Apparatus and methods for treating hollow anatomical structures|
|US20020147445 *||Jun 3, 2002||Oct 10, 2002||Farley Brian E.||Expandable vein ligator catheter and method of use|
|US20020148476 *||Jun 7, 2002||Oct 17, 2002||Farley Brian E..||Method of ligating hollow anatomical structures|
|US20040254621 *||Dec 16, 2003||Dec 16, 2004||Jones Christopher S.||Expandable catheter having two sets of electrodes, and method of use|
|US20040267258 *||Jul 28, 2004||Dec 30, 2004||Vnus Medical Technologies, Inc.||Expandable vein ligator catheter having multiple leads, and method|
|US20060030849 *||Aug 5, 2004||Feb 9, 2006||Vnus Medical Technologies, Inc.||Methods and apparatus for coagulating and/or constricting hollow anatomical structures|
|US20120289947 *||Jan 18, 2011||Nov 15, 2012||Wolfgang Neuberger||Device and method for removing veins|
|USRE33925 *||Dec 8, 1988||May 12, 1992||Cordis Corporation||Electrosurgical catheter aned method for vascular applications|
|USRE40863 *||Oct 22, 1993||Jul 21, 2009||Boston Scientific Scimed, Inc.||Apparatus and method for sealing vascular punctures|
|DE3738429A1 *||Nov 12, 1987||May 24, 1989||Osypka Peter||Vorrichtung zum erweitern und/oder eroeffnen von blutgefaessen|
|EP0292172A2 *||May 9, 1988||Nov 23, 1988||Advanced Interventional Systems, Inc.||Apparatus for thermal treatment of body tissue|
|EP0633003A1 *||Jun 23, 1994||Jan 11, 1995||Jean Parvulesco||Medical instrument for electrocoagulation|
|WO1995029644A1 *||Apr 28, 1995||Nov 9, 1995||Willmen Hans Rainer||Electrosurgical instrument for therapeutic treatment of varices|
|WO2002017805A1 *||Jul 11, 2001||Mar 7, 2002||Ethicon Endo Surgery Europe||System for varicose vein treatment|
|U.S. Classification||606/50, 606/40|
|International Classification||A61B18/14, A61B18/12|
|Cooperative Classification||A61B18/12, A61B18/1402, A61B18/1206, A61B18/14, A61B2018/0066|
|European Classification||A61B18/12G, A61B18/12, A61B18/14|