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Publication numberUS3310051 A
Publication typeGrant
Publication dateMar 21, 1967
Filing dateDec 10, 1963
Priority dateDec 10, 1963
Publication numberUS 3310051 A, US 3310051A, US-A-3310051, US3310051 A, US3310051A
InventorsSchulte Rudolf R
Original AssigneeSchulte Rudolf R
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Surgical reservoir for implantation beneath the skin
US 3310051 A
Abstract  available in
Previous page
Next page
Claims  available in
Description  (OCR text may contain errors)

arch 21, 1967 R. R. SCHULTE 3,31%051 SURGICAL RESERVOIR FOR IMPLANTATION BENEATH THE SKIN Filed Dec. 10, 1963 SCALP-// rfmaw United States Patent 3,310,051 SURGICAL RESERVGIR FOR Iii PLANTATION BENEATH THE SKIN Rudolf R. Schulte, 3328 Calle Fresno, Santa Barbara, Calif. 93185 Filed Dec. 10, 1963, Ser. No. 329,443 2 Claims. (Cl. 128-216) This invention relates to a surgical implant which provides a reservoir located conveniently to the skin of a person which may be utilized to introduce, withdraw, or mix fluids in regions located farther inside the body.

There are numerous instances Where repetitive samplings of body fluids need to be made, or in which repetitive introductions or medication must be made to interior regions. An example i the repetitive sampling of cerebro-spinal fluid, and vthe introduction of medication thereto, such as in the treatment of cryptococcal meningitis or tubercular meningitis. Medication for these diseases is often only marginally effective if given intravenously, because in order to supply the concentration needed at the situs of the ailment, the total dosage in the body would have to be too high. In fact, these diseases have been unmanageable with intravenous injections principally for this reason. However, if the medications are injected at the situs of the ailment, the local concentration can be made high enough to be effective, and the diseases may be controlled, even though the total dosage in the body is relatively low.

A concurrent problem associated with the foregoing is that concentration levels need to be maintained at the situs over a protracted period of time. To make repeated injections by means of repetitive punctures is obviously undesirable, and in many regions of the body soon becomes impossible. One reason is that fibrosis develops around t-he multiple needle tracks and renders access increasingly diflicult, particularly in the brain. Furthermore, repeated punctures of the brain are inherently undesirable. While the examples given in this specification relate to treatment of regions within the skull, clearly the same criteria apply to ailments in other regions of the body.

It is an object of this invention to provide a device which, once installed, gives continuous access to internal regions of the body without requiring additional needle penetrations into these regions. Instead, a tubular portion of the device remains in the body and extends to the affected area where it serves as a continuously-available conduit placed there but once. Thereafter, a syringe or other device need only be placed in fluid communication with this conduit to inject, Withdraw or mix fluids in the interior region.

Still another object of the invention is to provide a mixing or flushing reservoir into which fluids may readily be injected or from which they may readily be withdrawn. An optional object is to provide such a reservoir which may also serve to provide surge-generatiug means of flush and mix fluids in it and in the region under treatment.

A device according to this invention comprises a tube having a central passage, the tube being adapted to be inserted in to the body so that its passage communicates with a selected region therein. A capsule is adapted to be connected to this tube and to be placed beneath the skin of the body. This capsule comprises an enclosure which has an internal periphery and a first and second wall, these walls facing each other inside the capsule. The wall next to the skin is tolerant to, and self-sealing after, needle puncture. One of the walls has a passage therethrough in fluid communication with the passage through the tube.

According to a preferred but optional feature of the invention, one of the walls is flexible and palpable through the skin by force exerted by the hand. The material of the flexible wall is flexible enough to be moved toward the other wall and thereby reduce the volume of the capsule and also sufficiently springy to return to its normal unstressed condition, thereby providing for pumping means to create bi-directional flow in the passages for mixing purposes.

The above and other features of this invention will be fully understood from the following detailed description and the accompanying drawings in which:

FIG. 1 is a cross-section of a portion of a skull, showing the device of the invention, partly in cutaway crosssection and in its normal, unstressed condition;

FIG. 2 is a top view of the invention, partly in cutaway cross-section;

FIG. 3 is a bottom view of the device taken at line 33 of FIG. 1; and

FIG. 4 is a fragmentary cross-section of a portion of FIG. 1, showing the device in another of its conditions.

FIG. 1 illustrates a skull 10, showing the scalp 11 and the bone 12 of the skull surrounding the brain 13. The drawing of the anotomical portions is simplified because these form no portion of the present invention. It will be noted that the device is installed within a burr hole 14 having an internal wall 15 in the bone of the skull, and is held beneath the skin of the scalp by means of a sutured slit 16.

The reservoir elements 20 comprising the invention includes a tube 21 having a central passage 22 and a closed end 23. Perforations 24 through the wall provide for fluid communication between the passage and the outside of the tube. The tube is connected to a capsule 25 by means of a connector 26, which connector is attached to a passage extension 27 which has a passage 28 that enters the capsule itself through one wall thereof. The capsule has a boss 29 which fits within burr hole 14 and provides for lateral restraint of the device. The capsule outward of the boss rests on the skull so as to give longitudinal restraint.

The capsule is a continuou enclosure and includes a circumferential periphery defined by circumferential edge 30. First and second interior walls 31, 32 are provided on opposite sides of the periphery. The first wall lies closer to the skull, and includes an interior crown 33 which surrounds the opening 34 of passage 28 into the interior of the capsule. The crown has a plurality of notches 35 formed therein.

Second wall 32 is generally domed and has a central section which is thicker than the edges. This wall is flexible and, as best shown in FIG. 4, is adapted to be palpated by finger pressure through the scalp to move it toward the first wall, thereby reducing the volume of the capsule. In order to prevent the first and second walls from adhering to each other and closing the passages, the crown is provided to hold them apart. However, the notches provide for fluid flow past the crown to the passage even when the second wall is pressed against the crown.

The entire structure is, of course, made of material which is compatible with the human tissue with which it comes in contact. A convenient substance is silicone rubber manufactured by Dow Corning Company, of Midland, Mich. The thickness of the second wall is selected such that it is springy enough to restore itself to its normal, unstressed condition shown in FIG. 1, and yet sufliciently flexible that it can be deflected to the configuration shown in FIG. 4. It is also tolerant to repetitive needle punctures (with a resonable number), because, as best shown in FIG. 1, material may be in- 3 jected from a hypodermic syringe 36 by puncturing the scalp and the second wall with the needle. When the needle is withdrawn, the material of the second wall will seal the opening made by the needle.

The use of the device should be evident from the foregoing. If it is desired either to withdraw fluid from region 37 within the brain or to introduce medication thereto, the tube will be forced into this region by means well known in the surgical arts. Once in place, this tube is connected to the capsule, and the capsule is placed in position as shown, and the scalp sutured over the capsule. The capsule is filled with fluid, which, after a time, will be identical with fluid in the region under study, particularly if the device is pumped for a while, either by depressing the second wall or by pumping with a syringe. The fluid may be withdrawn for sampling by a hypodermic syringe. Also, medication may be introduced to the region by a syringe as shown, mixing being attained either by depressing the second wall or by pumping with the syringe.

It will thereby be seen that this device provides a reservoir of fluid which in effect is an extension of a region under treatment or study. Only one puncture of the brain or other region is necessary because the tube remains in place for sensible periods of time to provide a continuously-available conduit to the region, and the dome i available for introduction and withdrawal of material even were the second wall to be too stifl to flex. On the other hand, should the device be made flexible enough for this purpose, then even better results may be attained as a result of the more complete bi-directional flow attainable thereby.

This invention is not to be limited by the embodiment shown in the drawings and described in the description which is given by way of example and not of limitation, but only in accordance with the scope of the appended claims.

I claim:

1. A reservoir element for implantation in a human being comprising: a tube having a central passage and adapted to be inserted into the body so that its passage communicates with a selected region to be treated; and

a capsule of a size to be placed beneath the skin so as to rest between the skin and the bony structure of the body, said capsule comprising an envelope having an in ner cavity bounded by a first and a second wall, the first wall being adapted to lay on surface to surface contact with said bony structure, the second wall being domed and springily flexible so as to be deformable and movable toward the first wall so as to reduce the volume of the cavity as the result of external force thereon, and to return to its dome shape of its own accord when the force is removed, there being a passage through said first wall connected to the passage in the tube, and a crown formed inside the cavity around the entrance of the passage thereinto, said cr-own having notches thereon, whereby the walls are prevented from adhering to each other and also from shutting off flow through the passage when the capsule is compressed, the second wall being made of material which permits puncture by a needle and is self-sealing after the needle is withdrawn.

2. A reservoir element according to claim 1 in which a boss surrounds the capsule passage on the outside surface of the first wall, whereby to fit in a hole in the said bony structure and thereby to provide lateral positioning support for the capsule.

References Cited by the Examiner UNITED STATES PATENTS 513,238 1/1894 Lalonde 128-126 3,021,842 2/1962 Flood 128215 3,111,125 11/1963 Schulte 128350 3,144,866 8/1964 Ellis 128232 3,154,074 10/1964 Harrison l28232 FOREIGN PATENTS 790,220 2/ 1958 Great Britain.

OTHER REFERENCES Lancet, vol 2 (63), No. 7315, Nov. 9, 1963, pp. 983-84.

RICHARD A. GAUDET, Primary Examiner.


Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US513238 *Feb 23, 1893Jan 23, 1894 Joseph lalonde
US3021842 *Nov 5, 1958Feb 20, 1962John F FloodHypodermic needle guide
US3111125 *Nov 6, 1961Nov 19, 1963Schulte Rudolf RDrainage device
US3144866 *Aug 11, 1961Aug 18, 1964Briggs Castling & KellyDisposable douche syringe and bag
US3154074 *Oct 23, 1962Oct 27, 1964Lehn & Fink Products CorpInternal medicament applicator
GB790220A * Title not available
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3530492 *Dec 5, 1967Sep 22, 1970Ferber Jack RMethod and apparatus for administering hypodermic injections
US3613663 *Sep 9, 1968Oct 19, 1971Johnson Roger PApparatus to provide communication with the veins of a patient
US3640269 *Oct 24, 1969Feb 8, 1972Delgado Jose M RFluid-conducting instrument insertable in living organisms
US3731681 *Jan 14, 1972May 8, 1973Univ MinnesotaImplantable indusion pump
US3765414 *Mar 10, 1972Oct 16, 1973Hydro Med Sciences IncDrug release system
US3783868 *May 6, 1971Jan 8, 1974Gulf Oil CorpPercutaneous implant
US3796217 *May 17, 1973Mar 12, 1974Hydr Med Sciences IncDrug release system
US3831583 *Feb 5, 1973Aug 27, 1974Univ CalifImplantable bulb for inflation of surgical implements
US3864874 *Jan 29, 1973Feb 11, 1975Carroll Raymond LMethod and apparatus for introducing a fluid into the vascular system of a tree or similar plant
US3958562 *Dec 2, 1974May 25, 1976Hakim Company LimitedImplantable pressure sensor
US3971376 *Oct 2, 1974Jul 27, 1976Ceskoslovenska Akademie VedMethod and apparatus for introducing fluids into the body
US3998222 *May 15, 1975Dec 21, 1976Shihata Alfred ASubcutaneous arterio-venous shunt with valve
US4013074 *Apr 6, 1976Mar 22, 1977Siposs George GImplantable medication-dispensing device
US4026287 *Dec 10, 1975May 31, 1977Irene HallerSyringe with retractable cannula
US4160454 *Feb 14, 1977Jul 10, 1979University Of UtahImplantable catheter system
US4184497 *Aug 26, 1977Jan 22, 1980University Of UtahPeritoneal dialysis catheter
US4190057 *Dec 27, 1977Feb 26, 1980Thoratec Laboratories CorporationDevice for determining the patentcy of a blood vessel
US4253201 *May 24, 1979Mar 3, 1981Ross David AProsthesis with self-sealing valve
US4317452 *Feb 4, 1980Mar 2, 1982C. R. Bard, Inc.Body fluid drain
US4405305 *Feb 17, 1981Sep 20, 1983University Of Utah Research FoundationSubcutaneous peritoneal injection catheter
US4464178 *Nov 25, 1981Aug 7, 1984Dalton Michael JMethod and apparatus for administration of fluids
US4557724 *Aug 12, 1983Dec 10, 1985University Of Utah Research FoundationApparatus and methods for minimizing cellular adhesion on peritoneal injection catheters
US4559033 *Aug 12, 1983Dec 17, 1985University Of Utah Research FoundationApparatus and methods for minimizing peritoneal injection catheter obstruction
US4569675 *Sep 12, 1983Feb 11, 1986Infusaid CorporationTranscutaneous infusion system
US4585010 *Jul 2, 1984Apr 29, 1986Enrico AscerProcess and apparatus for measurement of outflow resistance
US4634424 *Apr 23, 1984Jan 6, 1987Windsor Medical, Inc.Multiple re-entry implantable septum and method of using same
US4673394 *Jan 17, 1986Jun 16, 1987Strato Medical CorporationImplantable treatment reservoir
US4687001 *Feb 14, 1977Aug 18, 1987The United States Of America As Represented By The Department Of Health And Human ServicesSubcutaneous fluid and culture chamber and implant technique
US4710167 *May 21, 1986Dec 1, 1987Applied Precision LimitedImplantable device for chronically injecting a substance, in particular a therapeutant
US4710174 *Dec 16, 1985Dec 1, 1987Surgical Engineering Associates, Inc.for dispensing medication
US4710177 *May 15, 1986Dec 1, 1987Smith Robert RSubcutaneous ventricular injection apparatus and method
US4767410 *Jun 19, 1987Aug 30, 1988Surgical Engineering Associates, Inc.Implantable infusion port
US4772261 *Jan 29, 1987Sep 20, 1988Board Of Regents, The University Of Texas SystemRepetitive fluid delivery into the vascular system
US4772270 *Jun 18, 1987Sep 20, 1988Catheter Technology Corp.Inseparable port/catheter tube assembly and methods
US4772276 *Jul 27, 1987Sep 20, 1988Catheter Technology Corp.Catheter tube coupling assembly and methods
US4781695 *Jul 11, 1986Nov 1, 1988Dalton Michael JImplantable fluid dispenser
US4857053 *Aug 29, 1988Aug 15, 1989Dalton Michael JMatrix septum
US4904241 *Oct 21, 1988Feb 27, 1990Medical Engineering Corp.Septum with a needle stop at the fluid transfer port
US4915690 *Feb 2, 1988Apr 10, 1990C. R. Bard, Inc.Micro-injection port
US4969870 *Jun 7, 1989Nov 13, 1990The Regents Of The University Of CaliforniaMethod and apparatus for intraosseous infusions
US5041098 *May 19, 1989Aug 20, 1991Strato Medical CorporationVascular access system for extracorporeal treatment of blood
US5092849 *Jan 24, 1990Mar 3, 1992Shiley Infusaid, Inc.Implantable device
US5122114 *Feb 1, 1991Jun 16, 1992Board Of Regents, University Of Texas SystemMethod of using intramedullary catheter
US5312364 *Aug 6, 1993May 17, 1994PyngIntraosseous infusion device
US5332398 *Apr 10, 1992Jul 26, 1994Board Of Regents, The University Of Texas SystemIntramedullary catheter
US5399168 *Jul 29, 1992Mar 21, 1995C. R. Bard, Inc.Implantable plural fluid cavity port
US5702414 *Sep 5, 1996Dec 30, 1997Optonol LtdMethod of implanting an intraocular implant
US5713858 *Apr 28, 1995Feb 3, 1998Medtronic, Inc.Permanently implantable guiding catheter
US5792104 *Dec 10, 1996Aug 11, 1998Medtronic, Inc.Dual-reservoir vascular access port
US5817052 *Dec 26, 1995Oct 6, 1998Pyng Medical Corp.Apparatus for intraosseous infusion or aspiration
US5836935 *Jan 28, 1997Nov 17, 1998Ashton; PaulImplantable refillable controlled release device to deliver drugs directly to an internal portion of the body
US5848989 *Jun 5, 1997Dec 15, 1998Davinci Biomedical Research Products, Inc.Implantable port with low profile housing for delivery/collection of fluids and implantation method
US5968058 *Jul 14, 1997Oct 19, 1999Optonol Ltd.Device for and method of implanting an intraocular implant
US6036721 *May 17, 1999Mar 14, 2000Cap IncorporatedPuncture closure
US6203513Nov 20, 1997Mar 20, 2001Optonol Ltd.Flow regulating implant, method of manufacture, and delivery device
US6228088Sep 20, 1995May 8, 2001Board Of Regents, The University Of Texas SystemCombination drill bit and intrametullary catheter and method of using same
US6468283Aug 26, 1999Oct 22, 2002Optonol, Ltd.Method of regulating pressure with an intraocular implant
US6478783May 26, 2000Nov 12, 2002H. Robert MooreheadAnti-sludge medication ports and related methods
US6510600Dec 4, 2000Jan 28, 2003Optonol, Ltd.Method for manufacturing a flow regulating implant
US6558342Jun 2, 1999May 6, 2003Optonol Ltd.Flow control device, introducer and method of implanting
US6623462Apr 17, 2002Sep 23, 2003Harmac Medical Products, Inc.Needle safety guard
US6726664Aug 6, 2001Apr 27, 2004Optonol Ltd.Flow control device, introducer and method of implanting
US6726678 *Feb 22, 2001Apr 27, 2004Isurgical, LlcImplantable reservoir and system for delivery of a therapeutic agent
US6736797Jun 19, 1998May 18, 2004Unomedical A/SSubcutaneous infusion set
US6824530Apr 18, 2002Nov 30, 2004Harmac Medical Products, Inc.Combination needle assembly and needle safety guard
US7063691Mar 16, 2004Jun 20, 2006Regents Of The University Of MinnesotaImplantable reservoir and system for delivery of a therapeutic agent
US7242982Dec 9, 2003Jul 10, 2007Medtronic, Inc.Overmold for a modular implantable medical device
US7263401Apr 29, 2004Aug 28, 2007Medtronic, Inc.Implantable medical device with a nonhermetic battery
US7317947Apr 29, 2004Jan 8, 2008Medtronic, Inc.Headset recharger for cranially implantable medical devices
US7481816Oct 27, 2003Jan 27, 2009Optonol Ltd.Intraocular implant, delivery device, and method of implantation
US7596399Apr 29, 2004Sep 29, 2009Medtronic, IncImplantation of implantable medical device
US7596408Apr 30, 2004Sep 29, 2009Medtronic, Inc.Implantable medical device with anti-infection agent
US7670310Dec 7, 2007Mar 2, 2010Optonol LtdFlow regulating implants
US7813811Feb 8, 2007Oct 12, 2010Neuropace, Inc.Refillable reservoir lead systems
US7844345Feb 8, 2007Nov 30, 2010Neuropace, Inc.Drug eluting lead systems
US7862531Jun 25, 2004Jan 4, 2011Optonol Ltd.Flow regulating implants
US7881796Jul 31, 2007Feb 1, 2011Medtronic, Inc.Implantable medical device with a nonhermetic battery
US8034016Dec 7, 2007Oct 11, 2011Optonol, Ltd.Flow regulating implants and methods of implanting
US8062270 *Jun 23, 2010Nov 22, 2011Spinal Generations, LlcMethod and device for delivering medicine to bone
US8086313Aug 5, 2009Dec 27, 2011Medtronic, Inc.Implantable medical device with anti-infection agent
US8109896Feb 11, 2008Feb 7, 2012Optonol Ltd.Devices and methods for opening fluid passageways
US8152792 *Sep 8, 2008Apr 10, 2012Kornel Ezriel ESubcutaneous drain for a body cavity
US8160720Sep 13, 2010Apr 17, 2012Neuropace, Inc.Refillable reservoir lead systems
US8190270Jan 10, 2012May 29, 2012Neuropace, Inc.Refillable reservoir lead systems
US8280478Aug 10, 2009Oct 2, 2012Medtronic, Inc.Evaluation of implantation site for implantation of implantable medical device
US8313454Mar 26, 2010Nov 20, 2012Optonol Ltd.Fluid drainage device, delivery device, and associated methods of use and manufacture
US8423156Feb 9, 2012Apr 16, 2013Neuropace, Inc.Drug eluting lead systems
US8486086Nov 7, 2011Jul 16, 2013Optonol, LtdFlow regulating implant, method of manufacture, and delivery device
US8808337Apr 21, 2009Aug 19, 2014Spinal Generations, LlcMethod and device for delivering medicine to bone
DE2124062A1 *May 14, 1971Dec 23, 1971 Title not available
DE2724231A1 *May 25, 1977Nov 30, 1978Affeld KlausImplantierbarer, auf einem nebenhoden oberhalb des durchtrennten samenleitgefaesses zu befestigender sammelbehaelter
EP0134340A1 *Aug 22, 1983Mar 20, 1985The University of Utah Research FoundationPeritoneal injection catheter apparatus
EP0134745A1 *Aug 31, 1984Mar 20, 1985Henri MeriauxInfusion device
EP0309092A1 *Aug 19, 1988Mar 29, 1989Infusaid, Inc.Implantable device
EP0822844A1 *Apr 15, 1996Feb 11, 1998Medtronic, Inc.Securing device for intercranial infusion port with filter and catheter
EP1426074A1 *Apr 15, 1996Jun 9, 2004Medtronic Inc.Securing device for intracranial infusion port with filter and catheter
EP1591140A1Apr 26, 2005Nov 2, 2005Ethicon Endo-Surgery, Inc.A surgically implantable injection port having a centered catheter connection tube
WO1990014857A1 *Jun 7, 1990Dec 8, 1990Univ CaliforniaMethod and apparatus for intraosseous infusions and aspirations
WO1996014834A1 *Nov 9, 1995May 23, 1996Univ Kentucky Res FoundImplantable refillable controlled release device to deliver drugs directly to an internal portion of the body
U.S. Classification604/175, 604/212
International ClassificationA61M39/02
Cooperative ClassificationA61M39/0208, A61M2210/0687
European ClassificationA61M39/02B
Legal Events
Feb 22, 1983ASAssignment
Effective date: 19830121