|Publication number||US3326216 A|
|Publication date||Jun 20, 1967|
|Filing date||Mar 30, 1964|
|Priority date||Mar 30, 1964|
|Also published as||DE1296299B|
|Publication number||US 3326216 A, US 3326216A, US-A-3326216, US3326216 A, US3326216A|
|Inventors||Wood Ernest C|
|Original Assignee||Peter B Samuels, Rene G Le Vaux|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (4), Referenced by (65), Classifications (16)|
|External Links: USPTO, USPTO Assignment, Espacenet|
June 20, 1967 E. c. WOOD HEMOSTATIC CLIi CONSTRUCTIONS 2 Sheets-Sheet 1 Filed March 30, 1964 IN VENTOQ Ernesz C. Wood LZZKMMQQ June 20, 1967 E. c. WOOD 3,326,216
, HEMOSTATIC CLIP CONSTRUCTIONS I Filed Marc 7h 50, 1964 2 Sheets-Sheet 2 INVENTOR- Ernesi C, Waod United States Patent 3,326,216 HEMOSTATIC CLIP CONSTRUCTIONS Ernest C. Wood, Los Angeles, Calif., assignor of one-third to Peter B. Samuels and one-third to Rene G. Le Vaux Filed Mar. 30, 1964, Ser. No. 355,810
9 Claims. (Cl. 128-325) I This invention relates to mechanisms useful in the strangulation of tubular members. Specifically, it is directed toward devices including hemostatic clips useful in the strangulation of blood vessels and other fluid ducts in the human body.
The particular application of this invention to the strangulation of blood vessels will serve as an illustration of the inventive concepts enclosed herein. It will be appreciated, however, that the mechanisms embodying the concepts of this invention can be adapted for the closing of other tubular structures at intermediate points as well as near their open ends.
In the course of a surgical operation, a surgeon must often sever one or more blood vessels. :It is desirable to provide means for closing the ends of the severed vessels, at least until the end of the operation, to stop bleeding that could interfere with the performance of the operation as well as present unnecessary risks to the patient.
Conventional means for closure consist of ligatures or the like tied about the individual vessels at the desired point of strangulation. The customary technique provides for the separate clamping of each vessel after the incision has been made. After clamping the vessels, a ligature is secured about each vessel providing closure and permitting the rem-oval of the clamps. In some instances a great number of vessels must be severed after requiring one or more hours for proper closure at which point the operation may proceed. It will be apparent that an improved technique for closure -will not only obviate the excessive expenditures of time by the surgeon and his assistants under conventional practice but also the dangers to the patient inherent in any delay.
It is an object of this invention to provide mechanisms for use in the strangulation of blood vessels whereby the time required for closure is materially reduced and Where- -by bleeding can be terminated without the use of the excessive combination of clamping and tying operations.
It is a more particular object of this invention to provide improved mechanisms for the strangulation of blood vessels and the like whereby the blood vessels may be sealed off in a highly efiicient manner to prevent bleeding during an operation and whereby the operation can proceed with a minimum loss of time as well as blood thereby to maintain conditions most favorable to the patient.
It is a specific object of this invention to provide an improved design for a hemostatic clip, which is adapted to meet the foregoing objects.
These and other objects of this invention will hereinafter appear and for purposes of illustration, but not of limitation, specific embodiments of the invention are shown in the accompanying drawings, in which FIG. 1 is a plan view of the hemostatic clip applicator structure;
FIG. 2 is an enlarged sectional elevational view of the jaws of the applicator structure;
FIG. 3 is an enlarged top view of one jaw of the applicator, taken about line 3-3 of FIG. 2;
FIG. 4 is an enlarged cross-sectional view of the jaws taken about line 44 of FIG. 2;
FIG. 5 is a view of the applicator along line 55 of FIG. 1;
FIG. 6 is an elevational view of the applicator;
FIG. 7 is a view of the applicator taken about line 77 of FIG. 1.
FIG. 8 is a front elevational view of a magazine construction adapted to hold a plurality of the clips of this invention;
FIG. 9 is an end elevational view of the holding means suitable for hemostatic clips made in accordance with this invention shown in FIG. 8.
FIG. 10 is a view of the holding means taken about line 10-10 of FIG. 8;
FIG. 11 is a sectional elevational view showing the spatial relation of the clip and magazine;
FIG. 12 comprises an enlarged cross-sectional view illustrating the relative positions of clip, applicator and magazine during loading of the applicator with a clip from the magazine;
FIG. 13 is an enlarged sectional View illustrating the manner in which the jaw portions of the applicator provide for closing the clip;
FIG. 14 is a perspective view of a hemostatic clip construction designed in accordance with the concepts of this invention.
FIG. 15 is an elevational view of the clip shown in FIG. 14;
FIG. 16 is a view of the clip taken about line 1616 of FIG. 15.
FIG. 17 is a cross-sectional view of the clip taken about line 1717 of FIG. 15.
FIG. 18 is a perspective view of a blood vessel with a clip clamped thereon; and
FIG. 19 illustrates the strangulation of a blood vessel effected by having a clip clamped thereon.
The hemostatic clip of this invention is adapted to be formed from a strip of deformable non-toxic material whereby it can be safely used in an operation. The clip to be fully described hereinafter defines a pair of arm portions with interfaces in opposed relationship. These interfaces, when clamped by means to be described, engage the outer surface of a blood vessel to effect the strangulation desired. I
The applicator of this invention includes jaw portions with defining means for receiving the outer faces of the arm portion of the clip. When so received the clip will be firmly held and there will be little tendency for the clip to be dislodged therefrom before being clamped to a blood vessel.
In order to further increase the efiiciency of this invention, a suitable magazine or holding means is provided for mounting a plurality of clips in position to be loaded between the jaws of the applicator for use. The holding means and associated clips can be sterilized and packaged whereby they can be stored indefinitely and will be ready for use at any time. The slots defined in the holding means are dimensioned to receive therein the end portion of the jaws of the applicator means, to permit the jaws to grasp the clip contained therein and extract it from the holding means thereby eliminating the necessity of handling the clip at any time between sterilization and use in the strangulation of a blood vessel.
The accompanying drawings illustrate the structures that embody the concepts of this invention. As illustrated in FIGS. 14 through 17, the hemostatic clip of this invention comprises an elongate strip 25 of deformable material having its end portions arranged in arms 28 in spaced apart parallel relation with the facing inner surfaces of the arms being formed intermediate their lateral edges with a valley or recessed portion 26 extending lengthwise through at least the end portion of the arms and preferably through the entire length thereof.
In the preferred practice, as illustrated, the clip is formed with but a single recessed portion which extends continuously through the central portion of the strip but it will be understood that the inner face of the strip may be formed with more than one such recessed portion in side by side parallel relation. The ridges 24 formed alongside the recessed portion are preferably formed to curvilinear shape and the inner surfaces are preferably, but not necessarily, formed with longitudinally spaced apart, crosswise extending serrations 29 which extend continuously crosswise of the strip from edge to edge.
The strip is formed of non-toxic material, such as stainless steel, plastics and like materials, which are capable of being deformed and which retain the amount of deformation for fixedly clamping the blood vessels therebetween.
In the illustarted modification, the bail portion 30 of the strip intermediate the spaced arms 28 is bent to substantially V-shape but it will be apparent that the portion intermediate the arms may be formed to other contours, such as U-shape, rounded shape, or other polygonal shape.
The depth and width of the recess 26 is not sufficient to noticeably weaken the clip, yet adequate to leave ridges 24 that will impress a circumferential band of compression about the blood vessel whereon the clip is attached.
The crosswise extending serrations are dimensioned to have a depth and width substantially equal to the depth and width of the recess 26, and spaced to permit at least one and preferably more than one such serration to be in contact with the surface of the blood vessel upon which the clip is attached, yet not so close as to permit the distance between the center lines of the serrations to be less than twice the width of recess 26.
FIGS. 1 through 6 illustrate an applicator 10 and details of various portions thereof. The applicator structure comprises two pivotally joined elongate members 11 and 11 each providing a cooperating jaw member 13 on one side of the pivot 12, and cooperating handle portions 11 on the other side of the pivot. Means are provided between the handle portions resiliently to urge the handle portions in the direction away from each other and correspondingly to urge the jaw portions 19 in the direction away from each other but between certain limits, as will hereinafter be defined. For these purposes, there is provided a leaf spring 15 which is formed 15' intermediate its ends to offset the end portions 15 and 15 in normal position, fastened to one handle portion 11 at 16 and slidably connected to the other handle portion.
As best shown in FIG. 5, the movable end 23 of the curvilinear leaf spring 15 defines as lot 22 which is adapted to receive a hook 17 fixed to the handle portion 11. It will be apparent that pressure exerted in the finger holes 18 directed to bring the handles together will cause the movable end portion of the spring 15 to slide relative to its associated handle portion. Similarly, removal of the pressure from the finger holes will permit the spring 15 to urge apart the handle portions and their associated jaw portions, the movable end of the spring sliding relative to its associated handle portion until the end of the slot 22 engages the hook 17 as shown in FIG. 5, thereby limiting the separation of the handle portion 11 and hence the separation of the jaws 13.
Further limiting the separation of the jaws and associated handle portions is the interaction of pin 37, shown in FIG. 1, firmly secured to one of the elongate members 11 or 11 and the edges of hole 38 in the other elongate member through which the pin 37 passes. Both the pin and the hole are preferably located on the handle side of the pivot 12 in a position close to the pivot on portions of the elongate members having mutually sliding interfaces. The hole and pin are dimensioned to permit the pin to move freely in the hole, its motion defining an are about pivot 12, the hole dimensioned as to limit the separation of the handle portion 11 to that separation to which the handles are limited by the hook 17 engaging the end of the slot 22.
FIG. 3 provides an illustration of the preferred construction of the jaws of the applicator. Each jaw defines a body portion 30 and a lip portion 19 with said lip being angularly offset from the body portion. The contact surface of each lip portion is in a coplanar relationship to the surface of the body portion of its associated jaw, the lip and body of each jaw being formed with a blind groove 20 extending continuously throughout the length of the body portion and terminating just short of the end of the jaw thereby to form a ridge 21 on the outer end of the lip portion 19. In the preferred practice, it is desirable to have the recessed portions located centrally along the inner face of the jaw members and to extend continuously about the bend and to terminate in the body portions as illustrated in FIG. 3. The ridge 21 is formed to provide an abrupt abutment at the end of the recessed groove. The straight portion of the blind groove within the lip portion of the jaw is dimensioned to have a length slightly greater than the length of a closed hemostatic clip, a width dimensioned comfortably to receive said clip, and a depth sufiicient to provide a firm hold thereon. As will hereinafter appear, the said ridges and grooves provide for the extracting of the clip 25 from a clip magazine as well as the firm gripping of the clips when held by the jaws.
FIG. 8 illustrates a magazine designed to hold a plurality of clips and FIGS. 9 and 10 the internal features thereof.
As illustrated in the drawings, the clip holder 31 comprises a rigid body in the form of a substantially rectangular block 40 having a recessed portion across the top and down the sides with the recessed portion 32 across the top being formed of V-shape or other shape corresponding to the hail of the clip and dimensioned to have a length corresponding to the length of the clip and a width slightly greater than the width of the clip. The recessed portion 34, which extend downwardly along the sides of the body from the opposite end of the top recess, are dimensioned to have a width slightly greater than the width of the clip and the jaw portions of the applicator with the bail seated firmly on the saddle portion 32 of the recess and with the arms extending downwardly in the recessed portion 34 with the ends of the clip terminating short of the ends of the recessed portions by an amount 7 which corresponds to the spaced relation between the end of the recessed portion 20 and the end of the jaw portion or slightly greater.
In the use of this invention for the strangulation of blood vessels as shown in FIG. 18, the hook 17 on the handle portion 11 of the applicator is normally positioned relative to the extreme end of the slot 22 in leaf spring 15 as to limit the separation of the lip portions 19 of the jaws 13 to slightly less than the spread of the outer faces of the parallel arm portions 28 of clip 25. It will be appreciated that on inserting the applicator lips 19 into the defined slot 32 in the clip holder 31 to engage the clip 25, the ridges 21 on the ends of the lips may not easily pass over outer faces of the parallel arm portions 28. Rather, it is necessary to forcefully push the lips 19 into the holder thereby causing a sufficient separation of the lips to permit the ridges 21 to slide along the parallel arms of the clip. As illustrated in FIG. 12, after sliding the entire length of the arm portions of the clip, the ridges 21, it will be appreciated, snap into the gap 35 resulting from the proper dimensioning of the clip relative to the depth of the recess 32. Moreover, it will be noted that the width of the grooves 20 in the applicator lips are dimensioned approximately equal to the thickness of the clips 25. These two features in combination permit the clip to be received in fitting relation within the recessed portion 20. As the jaws of the applicator are withdrawn upwardly from the holder, the clip will tend to remain in the holder until the abutment 21, formed at the end of the slot, comes into contact with the ends of the clip arms, preferably to position the clip in the jaw members. Continued withdrawal of the applicator jaws will effect displacement of the clip from the holder with the clip properly positioned between the jaw members. The clip will be firmly held thereby, with little tendency for the clip to fall away from the lips and, in this connection, there is no necessity for pressing the jaws together to hold the clips.
The open ends of a clip can be placed on opposite sides of the severed end of a blood vessel and, when pressure is applied through the finger holes 18 and handles 11 of the applicator to urgethe jaw members in the direction towards each other, the clip held by the jaws will be clamped as shown in FIG. 13. The interfaces on the ends of the clip arms being the first portions to come in contact, the remainder of the interfaces encircling the blood vessel and pressing together, strangulating the vessel as shown in FIG. 18.
The clips are designed to tightly seal the blood vessel when clamped thereon and, therefore, the use of ligatures in an operation can be greatly diminished. As illustrated in FIG. 19, the ridges of the opposed interfaces of the clip engage the surface of the blood vessel at multiple locations 24 whereby more than one tight seal is formed. The advantage of several separate sealing rings in a given length of blood vessel over one single seal is that the clamping force exerted by the clip is concentrated in the circumferential compression band impressed by the ridges on the clips interfaces rather than distributed over the enclosed length of the vessel clamped. To adequately seal the vessel less clamping pressure need be applied than is necessary with the clip with small interfaces. Such reduces the danger of crushing the vessel walls. The multiple crosswise serrations on the clip interfaces insure a firm hold on the blood vessel even with the light clamping pressure necessary to effect strangulation thereby preventing bleeding and providing an additional safety feature insuring that if the clamping pressure used to close the clip is excessive, part of the vessel upon which the clamp is fixed will remain uncrushed.
The design of the clip construction 25, which represents the preferred design, is particularly important. Thus, the provisions of the parallel portions 28 serves to insure a firm gripping action by the applicator. These straight sections of the clip are readily seated in the grooves 20 in the lips 19, the ridges 21 preventing the clip from sliding from the groove.
The clip of this invention is preferably formed of surgical metals which are non-toxic and which therefore can be tolerated within the body for indefinite periods of time. Representative of such metals are stainless steel, platinum and tantalum. It is also contemplated that the clips be formed of less expensive non-toxic non-metallic materials such as plastic, or materials which are slowly absorbable in body fluids, such as collagen, gelatin, albumin, dried blood, synthetic materials, and the like.
It will be understood that various changes can be made in the above described hemostatic clip and applicator constructions which provide the characteristics of this invention without departing from the spirit thereof, particularly as defined in the following claims.
1. A hemostatic clip formed of elongate strips of nontoxic material comprising a pair of arms interconnected at one end and open at the other with the arms arranged in laterally spaced apart relation, at least one longitudinal valley and at least one crosswise serration in the interior surfaces of the arms facing one another.
2. A clip construction in accordance with claim 1 wherein said strip defines a V-shaped configuration and comprises a thin, essentially rectangular cross-section, one long side of the rectangle indented to conform to the longitudinal valley on the clips interface, the depth and width of the valley sufiicient to allow the ridges alongside to define multiple circumferential lines of contact upon the tubular member to which it is to be clamped without materially weakening the clip.
3. A clip construction in accordance with claim 1 wherein said strip defines a V-shaped configuration which includes a central fold, the arm portions of said V extending angularly from said fold and bending toward each other into an approximately parallel relationship, said longitudinal valley disposed on the mutually opposed interfaces.
4. A hemostatic clip as described in claim 1 having multiple longitudinal valleys in side by side relation on the interior face of the clip arms.
5. A hemostatic clip as defined in claim 2 having multiple longitudinal valleys.
6. A clip construction in accordance with claim 1 in which said strip is formed of a surgical metal which retains the shape to which it is deformed.
7. A clip construction in accordance with claim 1 in which said strip is formed of a material slowly absorbable in body fluids and selected from the group consisting of collagen, gelatin, albumin, dried blood and synthetic materials.
8. A clip construction in accordance with claim 1 in which said strip is formed from a non-metallic, deformable, sterile material.
9. A clip construction in accordance with claim 1 wherein the depth and the width of the serrations is approximately equal to that of the longitudinal valley.
References Cited UNITED STATES PATENTS 2,498,372 2/ 1950 Kortluche et al 128346 3,013,654 12/1961 Hofi 24-l37 3,056,408 10/1962 Brown 128325 FOREIGN PATENTS 137,393 5/1950 Australia.
RICHARD A. GAUDET, Primary Examiner.
G. E. MCNEILL, Assistant Examiner.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2498372 *||Oct 4, 1946||Feb 21, 1950||Kortlucke Jr Frederick F||Clamping device|
|US3013654 *||Jun 29, 1959||Dec 19, 1961||Robert F Hoff||Clothes line pins|
|US3056408 *||Apr 22, 1959||Oct 2, 1962||Brown Adolph M||Ligature clip|
|AU137393B *||Title not available|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3608554 *||Dec 22, 1969||Sep 28, 1971||Pilling Co||Surgical clamping means|
|US3631707 *||Jun 13, 1969||Jan 4, 1972||Weck & Co Inc Edward||Hemostatic clip applicator|
|US3732719 *||Dec 24, 1970||May 15, 1973||Weck & Co Inc E||Box-lock spanner spring|
|US3954108 *||Aug 27, 1974||May 4, 1976||Davis Hugh J||Occlusion clip and instrument for applying same|
|US4076120 *||Dec 10, 1976||Feb 28, 1978||American Hospital Supply Corporation||Cartridge for holding hemostatic clips|
|US4146130 *||Apr 8, 1977||Mar 27, 1979||Samuels Peter B||Hemostatic clip, clip applicator and cartridge therefor|
|US4166466 *||Oct 8, 1976||Sep 4, 1979||Jarvik Robert K||Repeating hemostatic clip applying instruments and multi-clip cartridges therefor|
|US4187712 *||Dec 4, 1978||Feb 12, 1980||Samuels Peter B||Hemostatic clip applicator|
|US4412539 *||May 11, 1981||Nov 1, 1983||United States Surgical Corporation||Repeating hemostatic clip applying instruments and multi-clip cartridges therefor|
|US4462404 *||Jan 22, 1982||Jul 31, 1984||Vormals Jetter & Scheerer Aesculap-Werke Aktiengesellschaft||Forceps- or tweezers-shaped surgical instrument|
|US4467803 *||Apr 1, 1982||Aug 28, 1984||Ngo Tuyen N||Oral temporary total hemostatic clamps|
|US4485953 *||Apr 5, 1982||Dec 4, 1984||Senco Products, Inc.||Surgical stapling instrument and cartridge therefor|
|US4519392 *||Oct 12, 1982||May 28, 1985||Lingua Robert W||Hemostasing muscle clips for needleless surgery|
|US4696396 *||Mar 9, 1987||Sep 29, 1987||Samuels Peter B||Hemostatic clip cartridge|
|US4844066 *||Apr 6, 1987||Jul 4, 1989||Richard-Allan Medical Industries, Inc.||Surgical clip|
|US4936447 *||Sep 26, 1989||Jun 26, 1990||Horizon Surgical Inc.||Hemostatic clip holder|
|US4961499 *||Jan 4, 1990||Oct 9, 1990||Pilling Co.||Hemostatic clip cartridge|
|US4972949 *||Jun 4, 1990||Nov 27, 1990||Horizon Surgical, Inc.||Hemostatic clip holder for small clips|
|US5104397 *||Apr 14, 1989||Apr 14, 1992||Codman & Shurtleff, Inc.||Multi-position latching mechanism for forceps|
|US5279416 *||Jun 5, 1992||Jan 18, 1994||Edward Weck Incorporated||Ligating device cartridge with separable retainer|
|US5282812 *||Jul 10, 1991||Feb 1, 1994||Suarez Jr Luis||Clamp for use in vascular surgery|
|US5431675 *||Oct 13, 1994||Jul 11, 1995||United States Surgical Corporation||Locking mechanism for endoscopic or laparoscopic surgical instruments|
|US5441509 *||Nov 9, 1994||Aug 15, 1995||Minnesota Mining And Manufacturing Company||Vessel clips|
|US5609598 *||Dec 30, 1994||Mar 11, 1997||Vnus Medical Technologies, Inc.||Method and apparatus for minimally invasive treatment of chronic venous insufficiency|
|US5800452 *||Mar 4, 1997||Sep 1, 1998||Hastings; John A.||Body piercing instrument holder|
|US5810847 *||Mar 6, 1997||Sep 22, 1998||Vnus Medical Technologies, Inc.||Method and apparatus for minimally invasive treatment of chronic venous insufficiency|
|US6013088 *||Nov 17, 1998||Jan 11, 2000||Karavidas; Theocharis||Surgical clamp with removable tips|
|US6044971 *||Jan 27, 1998||Apr 4, 2000||United States Surgical Corporation||Clip cartridge|
|US6217590||Jul 15, 1999||Apr 17, 2001||Scion International, Inc.||Surgical instrument for applying multiple staples and cutting blood vessels and organic structures and method therefor|
|US6228097||Jan 22, 1999||May 8, 2001||Scion International, Inc.||Surgical instrument for clipping and cutting blood vessels and organic structures|
|US6306150||Oct 2, 2000||Oct 23, 2001||Scion International, Inc.||Surgical clips for surgical instrument for stapling and cutting blood vessels and organic structures|
|US6391035||Mar 24, 2000||May 21, 2002||Timothy Appleby||Hemostatic clip removal instrument|
|US6460749||Oct 2, 2000||Oct 8, 2002||Scion International, Inc.||Surgical instrument for stapling and cutting blood vessels and organic structures|
|US6610073||Oct 19, 2000||Aug 26, 2003||Scion International, Inc.||Surgical clip, clip applicator and method therefor|
|US6715383 *||Nov 19, 2002||Apr 6, 2004||Chih-Ching Hsien||Wrench with angled function end|
|US6863675||Sep 20, 2002||Mar 8, 2005||Pilling Weck Incorporated||Ligating clip with integral penetrating hook|
|US6880699||Aug 27, 2002||Apr 19, 2005||Pilling Weck Incorporated||Cartridge for holding asymmetric surgical clips|
|US7052504||Nov 19, 2002||May 30, 2006||Teleflex Incorporated||Automated-feed surgical clip applier and related methods|
|US7131977||Aug 27, 2002||Nov 7, 2006||Pilling Weck Incorporated||Apparatus and method for removing a clip|
|US7211091||Aug 27, 2002||May 1, 2007||Pilling Weck Incorporated||Fingertip-actuated surgical clip applier and related methods|
|US7211092||Nov 19, 2002||May 1, 2007||Pilling Weck Incorporated||Automated-feed surgical clip applier and related methods|
|US7842045 *||Jan 19, 2005||Nov 30, 2010||Applied Medical Resources Corporation||Single fire vascular clip applier with disposable jaw|
|US8042687||Jun 10, 2008||Oct 25, 2011||Vesocclude Medical Llc||Hemostatic clip cartridge|
|US20040040875 *||Aug 27, 2002||Mar 4, 2004||Gallagher Richard J.||Cartridge for holding asymmetric surgical clips and method for loading surgical clips into a clip applier|
|US20040044352 *||Aug 27, 2002||Mar 4, 2004||Fowler David N.||Fingertip-actuated surgical clip applier and related methods|
|US20040044363 *||Aug 27, 2002||Mar 4, 2004||Fowler David N.||Apparatus and method for removing a clip|
|US20040059359 *||Sep 20, 2002||Mar 25, 2004||Wilson Donald F.||Ligating clip with integral penetrating hook|
|US20040097970 *||Nov 19, 2002||May 20, 2004||Hughett J. David||Automated-feed surgical clip applier and related methods|
|US20040097971 *||Nov 19, 2002||May 20, 2004||Hughett J. David||Automated-feed surgical clip applier and related methods|
|US20050277958 *||May 27, 2003||Dec 15, 2005||Levinson Melvin E||Surgical clip, clip applicator and method therefor|
|US20060124485 *||Oct 6, 2005||Jun 15, 2006||Kennedy Daniel L||Enhanced visibility cartridge with improved retainer|
|US20070083218 *||Oct 12, 2005||Apr 12, 2007||A Morris Steven||Coated ligating clip|
|US20090088783 *||Dec 5, 2008||Apr 2, 2009||Kennedy Daniel L||Non-snag polymer ligating clip|
|US20090152147 *||Jun 10, 2008||Jun 18, 2009||Cannady Freddy R||Hemostatic clip cartridge|
|DE3311830A1 *||Mar 31, 1983||Oct 20, 1983||Senco Products||Chirurgisches klammerinstrument und klammerntraeger|
|DE102005045006B3 *||Sep 21, 2005||Jan 4, 2007||Cardiomedical Gmbh||Case for haemostatic clamps for surgical use has bottom part containing pockets and bracket to hold clamp and top part with clamp parts to hold clamp securely in each clamp pocket|
|EP0000756A1||Jul 29, 1978||Feb 21, 1979||Charles H. Klieman||Surgical stapler|
|EP0000875A1||Jul 29, 1978||Mar 7, 1979||Charles H. Klieman||Hemostatic clip applicator|
|EP0494243A1 *||Sep 14, 1990||Jul 15, 1992||Horizon Surgical Inc||Hemostatic clip holder.|
|EP0567965A2 *||Apr 26, 1993||Nov 3, 1993||United States Surgical Corporation||Vessel clips|
|EP0583151A1 *||Aug 10, 1993||Feb 16, 1994||Edward Weck Inc.||Hemostatic clip cartridge with clip retaining means|
|WO1996020655A1 *||Nov 13, 1995||Jul 11, 1996||Vnus Med Tech Inc||Method and apparatus for minimally invasive treatment of chronic venous insufficiency|
|WO2013040306A1||Sep 14, 2012||Mar 21, 2013||Teleflex Medical Incorporated||Narrow profile surgical ligation clip|
|WO2013040378A1||Sep 14, 2012||Mar 21, 2013||Teleflex Medical Incorporated||Automatic surgical ligation clip applier|
|WO2013040467A2||Sep 14, 2012||Mar 21, 2013||Teleflex Medical Incorporated||Manual surgical ligation clip applier|
|U.S. Classification||606/158, 606/208, 606/207, 606/142|
|International Classification||A61B17/122, A61B17/12, A61B17/128, A61B17/28|
|Cooperative Classification||A61B17/2812, A61B17/1222, A61B17/128, A61B17/122|
|European Classification||A61B17/122, A61B17/122C, A61B17/128, A61B17/28D|